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ONTOLOGY REPORT - ANNOTATIONS

Term:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
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Accession:GO:0043162 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation.
Synonyms:exact_synonym: ubiquitin-dependent protein breakdown via the multivesicular body pathway;   ubiquitin-dependent protein catabolic process via the MVB pathway;   ubiquitin-dependent protein catabolism via the MVB pathway;   ubiquitin-dependent protein degradation via the multivesicular body pathway

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ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chmp1a charged multivesicular body protein 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624746:302,344...309,117
Ensembl chrNW_004624746:302,404...309,644 		JBrowse link
G Chmp1b charged multivesicular body protein 1B involved_in ISO (PMID:17984323) ComplexPortal PMID:17984323 NCBI chrNW_004624770:19,487,040...19,489,740 JBrowse link
G Chmp2a charged multivesicular body protein 2A involved_in ISO (PMID:17984323) ComplexPortal PMID:17984323 NCBI chrNW_004624832:45,293...48,314 JBrowse link
G Chmp2b charged multivesicular body protein 2B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624789:3,557,811...3,587,814
Ensembl chrNW_004624789:3,557,797...3,587,703 		JBrowse link
G Chmp3 charged multivesicular body protein 3 involved_in ISO (PMID:17984323) ComplexPortal PMID:17984323 NCBI chrNW_004624749:16,738,538...16,772,553
Ensembl chrNW_004624749:16,738,416...16,772,391 		JBrowse link
G Chmp4a charged multivesicular body protein 4A involved_in ISO (PMID:17984323) ComplexPortal PMID:17984323 NCBI chrNW_004624820:8,281,081...8,284,969 JBrowse link
G Chmp4b charged multivesicular body protein 4B involved_in ISO (PMID:17984323) ComplexPortal PMID:17984323 NCBI chrNW_004624842:5,454,616...5,505,454
Ensembl chrNW_004624842:5,450,900...5,505,418 		JBrowse link
G Chmp4c charged multivesicular body protein 4C involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624744:9,735,585...9,769,635
Ensembl chrNW_004624744:9,739,651...9,769,615 		JBrowse link
G Chmp5 charged multivesicular body protein 5 involved_in ISO (PMID:17984323) ComplexPortal PMID:17984323 NCBI chrNW_004624736:38,025,247...38,044,808 JBrowse link
G Chmp6 charged multivesicular body protein 6 involved_in ISO (PMID:17984323) ComplexPortal PMID:17984323 NCBI chrNW_004624801:10,063,284...10,070,322
Ensembl chrNW_004624801:10,063,614...10,070,320 		JBrowse link
G Chmp7 charged multivesicular body protein 7 involved_in ISO (PMID:17984323) ComplexPortal PMID:17984323 NCBI chrNW_004624758:18,524,338...18,538,909
Ensembl chrNW_004624758:18,524,290...18,538,083 		JBrowse link
G Hdac6 histone deacetylase 6 acts_upstream_of_or_within ISO (PMID:17785525) MGI PMID:17785525 NCBI chrNW_004624893:608,744...627,600
Ensembl chrNW_004624893:608,540...628,580 		JBrowse link
G LOC101715183 vacuolar protein sorting-associated protein 37B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624747:22,899,130...22,904,080 JBrowse link
G LOC101715774 vacuolar protein sorting-associated protein 37B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624747:22,906,077...22,933,690
Ensembl chrNW_004624747:22,900,640...22,933,594 		JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase involved_in ISO (PMID:20086093) BHF-UCL PMID:20086093 NCBI chrNW_004624731:5,855,678...5,954,119
Ensembl chrNW_004624731:5,862,626...5,951,421 		JBrowse link
G Plaa phospholipase A2 activating protein involved_in ISO (MGI:5883825|PMID:28413018) UniProt PMID:28413018 MGI:5883825 NCBI chrNW_004624736:31,127,955...31,169,680
Ensembl chrNW_004624736:31,127,955...31,169,739 		JBrowse link
G Ptpn23 protein tyrosine phosphatase non-receptor type 23 involved_in ISO (PMID:21757351) UniProt PMID:21757351 NCBI chrNW_004624730:73,975,490...74,004,454
Ensembl chrNW_004624730:73,975,655...74,004,572 		JBrowse link
G Rnf115 ring finger protein 115 involved_in ISO (PMID:23418353) UniProt PMID:23418353 NCBI chrNW_004624772:17,099,593...17,196,258
Ensembl chrNW_004624772:17,104,189...17,196,326 		JBrowse link
G Rnf126 ring finger protein 126 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624828:7,856,822...7,865,644
Ensembl chrNW_004624828:7,856,470...7,869,926 		JBrowse link
G Tsg101 tumor susceptibility 101 involved_in ISO (PMID:15611048)
(PMID:21757351)		 HGNC-UCL
UniProt		 PMID:15611048 PMID:21757351 NCBI chrNW_004624766:9,932,190...9,977,725
Ensembl chrNW_004624766:9,934,228...9,977,697 		JBrowse link
G Ubap1 ubiquitin associated protein 1 involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624736:38,573,139...38,633,193 JBrowse link
G Vps28 VPS28 subunit of ESCRT-I involved_in ISO (PMID:21757351) UniProt PMID:21757351 NCBI chrNW_004624735:12,426,687...12,430,698
Ensembl chrNW_004624735:12,426,543...12,430,698 		JBrowse link
G Vps37a VPS37A subunit of ESCRT-I involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624769:22,022,808...22,047,068
Ensembl chrNW_004624769:22,021,638...22,046,794 		JBrowse link
G Vps4a vacuolar protein sorting 4 homolog A involved_in ISO (PMID:22547407) UniProt PMID:22547407 NCBI chrNW_004624746:17,044,173...17,059,295
Ensembl chrNW_004624746:17,047,519...17,054,738 		JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B involved_in ISO (PMID:22547407) UniProt PMID:22547407 NCBI chrNW_004624792:9,098,291...9,128,931 JBrowse link
protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn23 protein tyrosine phosphatase non-receptor type 23 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624730:73,975,490...74,004,454
Ensembl chrNW_004624730:73,975,655...74,004,572 		JBrowse link
G Sh3d19 SH3 domain containing 19 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624858:2,558,035...2,750,502
Ensembl chrNW_004624858:2,560,049...2,750,467 		JBrowse link
G Snf8 SNF8 subunit of ESCRT-II involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624795:5,318,803...5,328,542
Ensembl chrNW_004624795:5,318,802...5,328,768 		JBrowse link
G Stam signal transducing adaptor molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624796:10,195,897...10,269,311
Ensembl chrNW_004624796:10,201,518...10,269,311 		JBrowse link
G Vps25 vacuolar protein sorting 25 homolog involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624795:1,428,448...1,432,583
Ensembl chrNW_004624795:1,428,448...1,432,574 		JBrowse link
G Vps28 VPS28 subunit of ESCRT-I involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624735:12,426,687...12,430,698
Ensembl chrNW_004624735:12,426,543...12,430,698 		JBrowse link
G Vps36 vacuolar protein sorting 36 homolog involved_in IEA TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000118 NCBI chrNW_004624748:1,880,542...1,908,541
Ensembl chrNW_004624748:1,881,411...1,908,505 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15225
    metabolic process 9678
      catabolic process 2291
        macromolecule catabolic process 1285
          modification-dependent macromolecule catabolic process 549
            modification-dependent protein catabolic process 545
              ubiquitin-dependent protein catabolic process 535
                ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 30
                  protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 7
Path 2
Term Annotations click to browse term
  biological_process 15225
    metabolic process 9678
      primary metabolic process 8614
        protein metabolic process 4537
          proteolysis 1455
            proteolysis involved in protein catabolic process 689
              modification-dependent protein catabolic process 545
                ubiquitin-dependent protein catabolic process 535
                  ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 30
                    protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 7
paths to the root