modification-dependent macromolecule catabolic process - Ontology Report

PMID:21873635

GO_Central

NCBI chr 3:115,850,117...115,930,259
Ensembl chr 3:115,850,185...115,930,273

Anapc10

anaphase promoting complex subunit 10

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr19:28,152,299...28,205,552
Ensembl chr19:28,152,299...28,205,467

Anapc11

anaphase promoting complex subunit 11

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr10:105,875,209...105,886,307

Anapc4

anaphase promoting complex subunit 4

involved_in

PMID:21873635

GO_Central

NCBI chr14:58,125,995...58,159,253
Ensembl chr14:58,125,995...58,157,770

Anapc5

anaphase-promoting complex subunit 5

involved_in

PMID:21873635

GO_Central

NCBI chr12:33,748,714...33,781,709
Ensembl chr12:33,748,735...33,781,781

Cdc20

cell division cycle 20

involved_in

(PMID:17443180)
PMID:21873635
(PMID:18753608)

PMID:17443180 PMID:18753608 PMID:21873635

NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512

Cdc23

cell division cycle 23

involved_in

PMID:21873635

GO_Central

NCBI chr18:26,236,891...26,260,611
Ensembl chr18:26,236,890...26,291,163

Cdc26

cell division cycle 26

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr 5:75,844,852...75,859,837

Cul3

cullin 3

acts_upstream_of_or_within

(PMID:10500095)

PMID:10500095

NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462

Ecrg4

ECRG4 augurin precursor

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:4454240|PMID:20404145)

PMID:20404145 PMID:21873635

MGI:4454240, RGD:13792537

NCBI chr 9:45,992,954...46,012,605
Ensembl chr 9:45,992,954...46,012,595

Fbxo31

F-box protein 31

involved_in

GO_REF:0000024
(PMID:19412162)

PMID:19412162

GO_REF:0000024

NCBI chr19:49,624,818...49,656,083
Ensembl chr19:49,627,686...49,656,010

Fzr1

fizzy and cell division cycle 20 related 1

involved_in

(PMID:18753608)
(PMID:14701726), (PMID:18662541), (PMID:21596315)
PMID:21873635

PMID:14701726 PMID:18662541 PMID:18753608 PMID:21596315 PMID:21873635

NCBI chr 7:8,332,029...8,343,953
Ensembl chr 7:8,332,029...8,343,952

LOC103692897

anaphase-promoting complex subunit CDC26 pseudogene

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr 7:73,462,396...73,462,806
Ensembl chr 7:73,462,368...73,462,806

Ube2c

ubiquitin-conjugating enzyme E2C

involved_in

PMID:21873635
(PMID:19822757), (PMID:9122200)

PMID:9122200 PMID:19822757 PMID:21873635

NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339

Ube2s

ubiquitin-conjugating enzyme E2S

involved_in

GO_REF:0000024
(PMID:19820702), (PMID:19822757)

PMID:19820702 PMID:19822757

GO_REF:0000024

NCBI chr 1:69,028,853...69,032,914
Ensembl chr 1:69,028,750...69,032,914

CAT tailing

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Nemf

nuclear export mediator factor

involved_in

(PMID:33406423), (PMID:33909987)
(MGI:6718911|PMID:33909987)

PMID:33406423 PMID:33909987

MGI:6718911

NCBI chr 6:87,791,650...87,835,826
Ensembl chr 6:87,791,656...87,835,841

cytoplasm protein quality control by the ubiquitin-proteasome system

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Rnf126

ring finger protein 126

involved_in

(PMID:24981174)

PMID:24981174

NCBI chr 7:9,939,359...9,946,963
Ensembl chr 7:9,938,229...9,946,738

mannose trimming involved in glycoprotein ERAD pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Edem1

ER degradation enhancing alpha-mannosidase like protein 1

involved_in

(PMID:25092655)

PMID:25092655

NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717

Edem2

ER degradation enhancing alpha-mannosidase like protein 2

involved_in

(PMID:25092655)

PMID:25092655

NCBI chr 3:144,201,604...144,227,423
Ensembl chr 3:144,201,605...144,227,485

Edem3

ER degradation enhancing alpha-mannosidase like protein 3

involved_in

(PMID:25092655)
(MGI:3654428|PMID:16431915)

PMID:16431915 PMID:25092655

MGI:3654428

NCBI chr13:63,858,282...63,920,538
Ensembl chr13:63,858,716...63,920,523

Man1a1

mannosidase, alpha, class 1A, member 1

involved_in

(PMID:27108681)

PMID:27108681

NCBI chr20:33,202,509...33,385,747
Ensembl chr20:33,202,517...33,385,824

Man1b1

mannosidase, alpha, class 1B, member 1

involved_in

(PMID:18003979), (PMID:21062743)

PMID:18003979 PMID:21062743

NCBI chr 3:8,143,877...8,165,007
Ensembl chr 3:8,143,381...8,165,006

modification-dependent protein catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Chfr

checkpoint with forkhead and ring finger domains

involved_in

(PMID:19182791)

PMID:19182791

NCBI chr12:46,504,497...46,538,104
Ensembl chr12:46,504,497...46,538,014

Fau

FAU ubiquitin like and ribosomal protein S30 fusion

involved_in

PMID:21873635

GO_Central

NCBI chr 1:203,350,226...203,351,741
Ensembl chr 1:203,350,189...203,351,742

Isg15

ISG15 ubiquitin-like modifier

acts_upstream_of_or_within
involved_in

(MGI:3511369|PMID:15485925)
PMID:21873635

PMID:15485925 PMID:21873635

MGI:3511369, RGD:13792537

NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435

Nedd8

NEDD8 ubiquitin like modifier

involved_in

PMID:21873635

GO_Central

NCBI chr15:29,153,556...29,165,575
Ensembl chr15:29,153,556...29,166,160

Rps27a

ribosomal protein S27a

involved_in

PMID:21873635

GO_Central

NCBI chr14:103,285,734...103,288,011
Ensembl chr14:103,285,734...103,288,011

Rps27a-ps12

ribosomal protein S27a, pseudogene 12

involved_in

PMID:21873635

GO_Central

NCBI chr18:24,242,836...24,243,530

Rps27a-ps28

ribosomal protein S27a, pseudogene 28

involved_in

PMID:21873635

GO_Central

NCBI chr 1:234,661,778...234,662,393
Ensembl chr18:24,242,880...24,243,492

Rps27a-ps5

ribosomal protein S27a, pseudogene 5

involved_in

PMID:21873635

GO_Central

NCBI chr X:34,393,983...34,394,450
Ensembl chr X:34,393,954...34,394,418

Rps27a-ps6

ribosomal protein S27a, pseudogene 6

involved_in

PMID:21873635

GO_Central

NCBI chr19:30,916,279...30,916,833
Ensembl chr19:30,916,304...30,916,801

Uba52

ubiquitin A-52 residue ribosomal protein fusion product 1

involved_in

PMID:21873635

GO_Central

NCBI chr16:18,918,614...18,920,807
Ensembl chr16:18,900,616...18,920,807

Uba7

ubiquitin-like modifier activating enzyme 7

acts_upstream_of_or_within

(MGI:3511369|PMID:15485925)

PMID:15485925

MGI:3511369

NCBI chr 8:108,665,289...108,674,099
Ensembl chr 8:108,665,292...108,674,099

Ubb

ubiquitin B

involved_in

PMID:21873635

GO_Central

NCBI chr10:47,247,629...47,249,335
Ensembl chr10:47,245,637...47,249,333

Ubc

ubiquitin C

involved_in

PMID:21873635

GO_Central

NCBI chr12:31,238,889...31,243,924
Ensembl chr12:31,239,152...31,243,925

Ube2l6

ubiquitin-conjugating enzyme E2L 6

acts_upstream_of_or_within

(MGI:3511369|PMID:15485925)

PMID:15485925

MGI:3511369

NCBI chr 3:69,873,025...69,888,042
Ensembl chr 3:69,873,424...69,888,048

ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Tent4b

terminal nucleotidyltransferase 4B

involved_in

(PMID:26950371)

PMID:26950371

NCBI chr19:18,807,616...18,868,969
Ensembl chr19:18,807,525...18,869,537

negative regulation of ER-associated ubiquitin-dependent protein catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

small glutamine rich tetratricopeptide repeat co-chaperone alpha

involved_in

(PMID:23129660)
GO_REF:0000024

PMID:23129660

GO_REF:0000024

NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458

Svip

small VCP interacting protein

involved_in

IBA
ISO
IC

PMID:21873635
(PMID:17872946)
PMID:17000876

PMID:17872946 PMID:21873635 PMID:17000876

RGD:13792537, RGD:10047192

NCBI chr 1:101,587,128...101,592,818
Ensembl chr 1:101,587,128...101,593,116

Usp14

ubiquitin specific peptidase 14

involved_in

(PMID:19135427)

PMID:19135427

NCBI chr18:1,018,111...1,057,727
Ensembl chr18:1,019,400...1,057,519

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bag5

BAG cochaperone 5

involved_in

(PMID:24475098)

PMID:24475098

NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970

BAG cochaperone 6

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(MGI:3808636|PMID:18678708)

UniProt
Ensembl
RGD

PMID:18678708

GO_REF:0000024 GO_REF:0000107 MGI:3808636

NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657

Camlg

calcium modulating ligand

involved_in

UniProtKB:Q9H9V4 (PMID:20553626)

PMID:20553626

NCBI chr17:8,992,697...9,003,576
Ensembl chr17:8,992,696...9,003,552

Ccar2

cell cycle and apoptosis regulator 2

involved_in

(PMID:23398316)

PMID:23398316

NCBI chr15:45,212,797...45,228,001
Ensembl chr15:45,212,803...45,227,636

Clec16a

C-type lectin domain containing 16A

acts_upstream_of_or_within

MGI:5648633 (MGI:5603233|PMID:24949970)

PMID:24949970

MGI:5603233

NCBI chr10:4,927,804...5,123,749
Ensembl chr10:4,928,030...5,123,578

Ddrgk1

DDRGK domain containing 1

involved_in

(PMID:28263186)

PMID:28263186

NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680

Eif3h

eukaryotic translation initiation factor 3, subunit H

involved_in

(PMID:32269044)

PMID:32269044

NCBI chr 7:83,091,045...83,174,436
Ensembl chr 7:83,091,039...83,174,451

Fhit

fragile histidine triad diadenosine triphosphatase

involved_in

ISO
ISS
IBA

(PMID:15313915)
GO_REF:0000024
PMID:21873635

PMID:15313915 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340

Gipc1

GIPC PDZ domain containing family, member 1

involved_in

(MGI:3807767|PMID:11546783)

PMID:11546783

MGI:3807767

NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997

Hsp90ab1

heat shock protein 90 alpha family class B member 1

involved_in
acts_upstream_of_or_within

PMID:16280321 PMID:24613385

GO_REF:0000024
(PMID:16280321)
(PMID:24613385)

UniProt
MGI
RGD

GO_REF:0000024

NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488

Klhl40

kelch-like family member 40

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:5586592|PMID:24960163)

PMID:24960163 PMID:21873635

MGI:5586592, RGD:13792537

NCBI chr 8:121,441,275...121,446,806
Ensembl chr 8:121,441,287...121,446,800

Map1a

microtubule-associated protein 1A

involved_in

(MGI:5703671|PMID:26609151)

PMID:26609151

MGI:5703671

NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899

Mtm1

myotubularin 1

acts_upstream_of_or_within

MGI:2450997 (MGI:5510937|PMID:23695157)

PMID:23695157

MGI:5510937

NCBI chr 6:488,691...506,964
Ensembl chr 6:488,969...506,860

N4bp1

Nedd4 binding protein 1

involved_in

PMID:21873635
(MGI:3829128|PMID:17592138)

PMID:17592138 PMID:21873635

MGI:3829128, RGD:13792537

NCBI chr19:20,222,811...20,273,570
Ensembl chr19:20,222,776...20,273,570

Nop53

NOP53 ribosome biogenesis factor

involved_in

(PMID:22522597)

PMID:22522597

NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902

Ogt

O-linked N-acetylglucosamine (GlcNAc) transferase

involved_in

GO_REF:0000107
(PMID:26678539)

PMID:26678539

GO_REF:0000107

NCBI chr X:66,771,278...66,816,148
Ensembl chr X:66,771,349...66,816,146

Park7

Parkinsonism associated deglycase

involved_in

(PMID:17015834)

PMID:17015834

NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970

Pbk

PDZ binding kinase

acts_upstream_of_or_within

MGI:5293435 (MGI:5293269|PMID:21715333)

PMID:21715333

MGI:5293269

NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014

Phf20l1

PHD finger protein 20-like 1

involved_in

GO_REF:0000024
(PMID:24492612)

PMID:24492612

GO_REF:0000024

NCBI chr 7:98,330,580...98,396,526
Ensembl chr 7:98,330,580...98,396,526

Rpl11

ribosomal protein L11

involved_in

GO_REF:0000024
(MGI:5897550|PMID:21804542)

PMID:21804542

GO_REF:0000024 MGI:5897550

NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599

Rybp

RING1 and YY1 binding protein

involved_in

(PMID:27060496)

PMID:27060496

NCBI chr 4:132,876,361...132,927,580
NCBI chr 4:132,876,260...132,929,075
Ensembl chr 4:132,876,361...132,928,316

Sdcbp

syndecan binding protein

involved_in

(PMID:25893292)
GO_REF:0000024

PMID:25893292

GO_REF:0000024

NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572

Senp1

SUMO specific peptidase 1

acts_upstream_of_or_within

MGI:3818522 (MGI:3818351|PMID:17981124)

PMID:17981124

MGI:3818351

NCBI chr 7:129,163,173...129,226,766
Ensembl chr 7:129,165,774...129,221,598

Shh

sonic hedgehog signaling molecule

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:3624046|PMID:16611981)

PMID:16611981

GO_REF:0000107 MGI:3624046

NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170

Smarcc1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1

acts_upstream_of_or_within

(MGI:5310666|PMID:22285184)

PMID:22285184

MGI:5310666

NCBI chr 8:110,111,097...110,214,727
Ensembl chr 8:110,111,122...110,214,720

Taf9

TATA-box binding protein associated factor 9

involved_in

(PMID:11278372)
GO_REF:0000107

PMID:11278372

GO_REF:0000107

NCBI chr 2:31,794,316...31,798,324
Ensembl chr 2:31,794,142...31,798,769

Tlk2

tousled-like kinase 2

involved_in

(PMID:20016786)

PMID:20016786

NCBI chr10:90,154,449...90,248,562
Ensembl chr10:90,156,813...90,248,561

Trim39

tripartite motif-containing 39

involved_in

IBA
IEA
ISS
ISO

PMID:21873635
GO_REF:0000107
GO_REF:0000024
(PMID:23213251)

PMID:23213251 PMID:21873635

GO_REF:0000024 GO_REF:0000107, RGD:13792537

NCBI chr20:2,003,320...2,017,175
Ensembl chr20:1,983,533...2,020,117

Ttc36

tetratricopeptide repeat domain 36

acts_upstream_of_or_within

MGI:5588394 (MGI:6362140|PMID:31537781)

PMID:31537781

MGI:6362140

NCBI chr 8:45,112,737...45,116,345

Ubxn1

UBX domain protein 1

involved_in

GO_REF:0000024
PMID:21873635
(PMID:20351172)

PMID:20351172 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr 1:205,765,212...205,769,236
Ensembl chr 1:205,745,120...205,816,520

Uchl5

ubiquitin C-terminal hydrolase L5

involved_in

(PMID:23770237)

PMID:23770237

NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502

Usp7

ubiquitin specific peptidase 7

involved_in

(PMID:26678539)

PMID:26678539

NCBI chr10:6,880,684...6,925,033
Ensembl chr10:6,828,795...6,925,355

Usp9x

ubiquitin specific peptidase 9, X-linked

involved_in

(PMID:33378666)

PMID:33378666

NCBI chr X:9,588,825...9,726,993
Ensembl chr X:9,588,825...9,696,711

Wac

WW domain containing adaptor with coiled-coil

involved_in

(PMID:22354037)

PMID:22354037

NCBI chr17:55,922,686...55,984,286
Ensembl chr17:55,923,123...55,982,301

negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Pabpn1l

PABPN1 like

acts_upstream_of_or_within

(MGI:6509513|PMID:32558204)

PMID:32558204

MGI:6509513

NCBI chr19:50,669,965...50,673,409
Ensembl chr19:50,669,967...50,673,366

Styx

serine/threonine/tyrosine interacting protein

involved_in

PMID:21873635
(PMID:28007894)

PMID:28007894 PMID:21873635

NCBI chr15:18,565,214...18,595,797
Ensembl chr15:18,564,633...18,593,524

negative regulation of ubiquitin-dependent protein catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Anks1a

ankyrin repeat and sterile alpha motif domain containing 1A

acts_upstream_of_or_within

(MGI:4461099|PMID:20100865)

PMID:20100865

MGI:4461099

NCBI chr20:5,963,658...6,117,139
Ensembl chr20:5,963,678...6,117,148

Cdkn2a

cyclin-dependent kinase inhibitor 2A

involved_in
acts_upstream_of_or_within

(PMID:16173922)
(PMID:18560357)
(MGI:5468878|PMID:23277542)

PMID:16173922 PMID:18560357 PMID:23277542

MGI:5468878

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

Csnk2a1

casein kinase 2 alpha 1

involved_in

UniProtKB:P19784|UniProtKB:P25686|UniProtKB:P67870 (PMID:28031292)

PMID:28031292

NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696

Csnk2a2

casein kinase 2 alpha 2

involved_in

UniProtKB:P25686|UniProtKB:P67870|UniProtKB:P68400 (PMID:28031292)

PMID:28031292

NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080

Hfe

homeostatic iron regulator

involved_in

(PMID:24904118)

PMID:24904118

NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502

Hipk2

homeodomain interacting protein kinase 2

involved_in

(PMID:21628596)

PMID:21628596

NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223

Pdcl3

phosducin-like 3

acts_upstream_of_or_within

(PMID:23792958)

PMID:23792958

NCBI chr 9:41,234,322...41,243,769
Ensembl chr 9:41,234,234...41,243,735

Pml

PML nuclear body scaffold

involved_in

(PMID:15195100)

PMID:15195100

NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971

Prmt6

protein arginine methyltransferase 6

involved_in

(MGI:5688415|PMID:26070566)

PMID:26070566

MGI:5688415

NCBI chr 2:197,927,750...197,932,980
Ensembl chr 2:197,927,220...197,933,648

Psen1

presenilin 1

involved_in

(MGI:4887523|PMID:20208556)

NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650

Psen2

presenilin 2

involved_in

(MGI:4887523|PMID:20208556)

NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174

Qrich2

glutamine rich 2

involved_in

(PMID:30683861)
(MGI:6277293|PMID:30683861)

PMID:30683861

MGI:6277293

NCBI chr10:101,669,235...101,685,281
NCBI chr10:101,685,289...101,686,370
NCBI chr10:101,686,862...101,688,070
NCBI chr10:101,688,451...101,697,637
Ensembl chr10:101,669,224...101,697,656

Rpl11

ribosomal protein L11

involved_in

(PMID:18560357)

PMID:18560357

NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599

Rpl23

ribosomal protein L23

involved_in

(PMID:15314173)

PMID:15314173

NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870

Rpl5

ribosomal protein L5

involved_in

(PMID:18560357)

PMID:18560357

NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290

Rps7

ribosomal protein S7

involved_in

(PMID:17310983)

PMID:17310983

NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145

small glutamine rich tetratricopeptide repeat co-chaperone alpha

involved_in

GO_REF:0000024
(PMID:23129660)

PMID:23129660

GO_REF:0000024

NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458

Sufu

SUFU negative regulator of hedgehog signaling

acts_upstream_of_or_within

MGI:1343085 (MGI:4355593|PMID:19684112)

PMID:19684112

MGI:4355593

NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577

Taf1

TATA-box binding protein associated factor 1

involved_in

(PMID:17237821)

PMID:17237821

NCBI chr X:66,640,915...66,716,543
Ensembl chr X:66,640,982...66,716,543

Trim39

tripartite motif-containing 39

involved_in

(PMID:19100260)

PMID:19100260

NCBI chr20:2,003,320...2,017,175
Ensembl chr20:1,983,533...2,020,117

Wnt1

Wnt family member 1

acts_upstream_of_or_within

(MGI:3628833|PMID:16601693)

PMID:16601693

MGI:3628833

NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651

nuclear polyadenylation-dependent antisense transcript catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

exosome component 10

involved_in

PMID:21873635

GO_Central

NCBI chr 5:158,995,318...159,018,946
Ensembl chr 5:158,995,313...159,018,940

nuclear polyadenylation-dependent CUT catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

exosome component 10

involved_in

PMID:21873635

GO_Central

NCBI chr 5:158,995,318...159,018,946
Ensembl chr 5:158,995,313...159,018,940

zinc finger CCHC-type containing 7

involved_in

PMID:21873635

GO_Central

NCBI chr 5:58,992,558...59,173,308
Ensembl chr 5:58,993,290...59,173,300

nuclear polyadenylation-dependent mRNA catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Exosc7

exosome component 7

involved_in

PMID:21873635

GO_Central

NCBI chr 8:122,773,607...122,798,943
Ensembl chr 8:122,773,591...122,799,270

Exosc8

exosome component 8

involved_in

PMID:21873635

GO_Central

NCBI chr 2:138,930,405...138,937,009
Ensembl chr 2:138,930,405...138,936,928

Exosc9

exosome component 9

involved_in

PMID:21873635

GO_Central

NCBI chr 2:119,416,028...119,426,981
Ensembl chr 2:119,388,715...119,427,051

Pnpt1

polyribonucleotide nucleotidyltransferase 1

involved_in

(PMID:16934922)

PMID:16934922

NCBI chr14:102,877,553...102,908,696
Ensembl chr14:102,877,553...102,908,696

nuclear polyadenylation-dependent rRNA catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

exosome component 10

involved_in

(PMID:16455498)
PMID:21873635

PMID:16455498 PMID:21873635

NCBI chr 5:158,995,318...159,018,946
Ensembl chr 5:158,995,313...159,018,940

Exosc2

exosome component 2

involved_in

PMID:21873635

GO_Central

NCBI chr 3:14,962,930...14,973,645
Ensembl chr 3:14,962,917...14,973,575

Exosc3

exosome component 3

involved_in

PMID:21873635

GO_Central

NCBI chr 5:59,573,849...59,579,065
Ensembl chr 5:59,573,886...59,579,060

Exosc7

exosome component 7

involved_in

PMID:21873635

GO_Central

NCBI chr 8:122,773,607...122,798,943
Ensembl chr 8:122,773,591...122,799,270

Exosc8

exosome component 8

involved_in

PMID:21873635

GO_Central

NCBI chr 2:138,930,405...138,937,009
Ensembl chr 2:138,930,405...138,936,928

Exosc9

exosome component 9

involved_in

(PMID:16455498)
PMID:21873635

PMID:16455498 PMID:21873635

NCBI chr 2:119,416,028...119,426,981
Ensembl chr 2:119,388,715...119,427,051

zinc finger CCHC-type containing 7

involved_in

PMID:21873635

GO_Central

NCBI chr 5:58,992,558...59,173,308
Ensembl chr 5:58,993,290...59,173,300

nuclear polyadenylation-dependent snoRNA catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

exosome component 10

involved_in

PMID:21873635

GO_Central

NCBI chr 5:158,995,318...159,018,946
Ensembl chr 5:158,995,313...159,018,940

zinc finger CCHC-type containing 7

involved_in

PMID:21873635

GO_Central

NCBI chr 5:58,992,558...59,173,308
Ensembl chr 5:58,993,290...59,173,300

nuclear polyadenylation-dependent snRNA catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

exosome component 10

involved_in

PMID:21873635

GO_Central

NCBI chr 5:158,995,318...159,018,946
Ensembl chr 5:158,995,313...159,018,940

zinc finger CCHC-type containing 7

involved_in

PMID:21873635

GO_Central

NCBI chr 5:58,992,558...59,173,308
Ensembl chr 5:58,993,290...59,173,300

nuclear polyadenylation-dependent tRNA catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

exosome component 10

involved_in

PMID:21873635

GO_Central

NCBI chr 5:158,995,318...159,018,946
Ensembl chr 5:158,995,313...159,018,940

Exosc2

exosome component 2

involved_in

PMID:21873635

GO_Central

NCBI chr 3:14,962,930...14,973,645
Ensembl chr 3:14,962,917...14,973,575

Exosc3

exosome component 3

involved_in

PMID:21873635

GO_Central

NCBI chr 5:59,573,849...59,579,065
Ensembl chr 5:59,573,886...59,579,060

Exosc7

exosome component 7

involved_in

PMID:21873635

GO_Central

NCBI chr 8:122,773,607...122,798,943
Ensembl chr 8:122,773,591...122,799,270

Exosc8

exosome component 8

involved_in

PMID:21873635

GO_Central

NCBI chr 2:138,930,405...138,937,009
Ensembl chr 2:138,930,405...138,936,928

Exosc9

exosome component 9

involved_in

PMID:21873635

GO_Central

NCBI chr 2:119,416,028...119,426,981
Ensembl chr 2:119,388,715...119,427,051

zinc finger CCHC-type containing 7

involved_in

PMID:21873635

GO_Central

NCBI chr 5:58,992,558...59,173,308
Ensembl chr 5:58,993,290...59,173,300

nuclear protein quality control by the ubiquitin-proteasome system

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Akirin2

akirin 2

acts_upstream_of_positive_effect

GO_REF:0000024
(PMID:34711951)

PMID:34711951

GO_REF:0000024

NCBI chr 5:49,108,231...49,122,566
Ensembl chr 5:49,108,220...49,122,568

Cul3

cullin 3

involved_in

GO_REF:0000024
(PMID:27561354)

PMID:27561354

GO_REF:0000024

NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462

Klhl15

kelch-like family member 15

involved_in

(PMID:27561354)
PMID:21873635
GO_REF:0000024

PMID:27561354 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr X:58,994,726...59,050,207
Ensembl chr X:58,995,461...59,046,069

oxidation-dependent protein catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Lonp1

lon peptidase 1, mitochondrial

involved_in

(PMID:12198491)
GO_REF:0000104

PMID:12198491

GO_REF:0000104

NCBI chr 9:1,447,444...1,459,771
Ensembl chr 9:1,447,447...1,459,771

polyuridylation-dependent mRNA catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Dis3l2

DIS3-like 3'-5' exoribonuclease 2

involved_in

GO_REF:0000104

GO_REF:0000104

NCBI chr 9:87,355,409...87,736,616
Ensembl chr 9:87,356,457...87,736,616

Tut4

terminal uridylyl transferase 4

involved_in

(MGI:6162305|PMID:28792939)

PMID:28792939

MGI:6162305

NCBI chr 5:123,201,723...123,306,582
Ensembl chr 5:123,203,003...123,306,465

Tut7

terminal uridylyl transferase 7

involved_in

(MGI:6162305|PMID:28792939)

PMID:28792939

MGI:6162305

NCBI chr17:4,849,287...4,903,542
Ensembl chr17:4,849,283...4,903,169

positive regulation of anaphase-promoting complex-dependent catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cdc20

cell division cycle 20

involved_in

PMID:21873635

GO_Central

NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512

Fzr1

fizzy and cell division cycle 20 related 1

involved_in

PMID:21873635

GO_Central

NCBI chr 7:8,332,029...8,343,953
Ensembl chr 7:8,332,029...8,343,952

positive regulation of ER-associated ubiquitin-dependent protein catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bcap31

B-cell receptor-associated protein 31

involved_in

UniProtKB:Q9BUN8 (PMID:18555783)

PMID:18555783

NCBI chr X:151,397,567...151,429,666
Ensembl chr X:151,397,576...151,428,506

Cav1

caveolin 1

involved_in

(PMID:24089527)

PMID:24089527

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

Herpud1

homocysteine inducible ER protein with ubiquitin like domain 1

involved_in

(PMID:18307982), (PMID:22045699)

PMID:18307982 PMID:22045699

NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424

small glutamine rich tetratricopeptide repeat co-chaperone alpha

involved_in

(PMID:23246001)

PMID:23246001

NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458

Ubqln1

ubiquilin 1

involved_in

IEA
ISS
ISO

GO_REF:0000107
GO_REF:0000024
(PMID:18307982)

PMID:18307982

GO_REF:0000024 GO_REF:0000107

NCBI chr17:6,439,002...6,477,096
Ensembl chr17:6,439,002...6,477,090

Ubqln2

ubiquilin 2

involved_in

(PMID:18307982)

PMID:18307982

NCBI chr X:17,853,086...17,856,505
Ensembl chr X:17,853,114...17,856,505

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Akt1

AKT serine/threonine kinase 1

acts_upstream_of_or_within
involved_in

(MGI:3589701|PMID:15937334)
(PMID:23512198)

PMID:15937334 PMID:23512198

MGI:3589701

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

Ankib1

ankyrin repeat and IBR domain containing 1

involved_in

PMID:21873635

GO_Central

NCBI chr 4:30,333,678...30,457,781
Ensembl chr 4:30,333,677...30,457,781

Arih1

ariadne RBR E3 ubiquitin protein ligase 1

involved_in

PMID:21873635

GO_Central

NCBI chr 8:59,777,378...59,879,762
Ensembl chr 8:59,777,379...59,880,245

Arih2

ariadne RBR E3 ubiquitin protein ligase 2

involved_in

PMID:21873635

GO_Central

NCBI chr 8:109,296,738...109,355,909
Ensembl chr 8:109,296,738...109,355,852

Atg7

autophagy related 7

acts_upstream_of_or_within

MGI:2446434|MGI:3587769|MGI:3691571 (MGI:5465208|PMID:23152632)

PMID:23152632

MGI:5465208

NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593

Aurka

aurora kinase A

acts_upstream_of_or_within

(MGI:3697244|PMID:17060449)

PMID:17060449

MGI:3697244

NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390

Axin1

axin 1

acts_upstream_of_or_within
involved_in

(MGI:3628833|PMID:16601693)
PMID:21873635

PMID:16601693 PMID:21873635

MGI:3628833, RGD:13792537

NCBI chr10:15,163,684...15,215,615
Ensembl chr10:15,163,684...15,215,615

Axin2

axin 2

involved_in

PMID:21873635

GO_Central

NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231

Bag2

BAG cochaperone 2

NOT|involved_in

UniProtKB:P10636 (MGI:6148635|PMID:19228967)

PMID:19228967

MGI:6148635

NCBI chr 9:35,970,033...35,980,677
Ensembl chr 9:35,970,033...35,980,721

Bbs7

Bardet-Biedl syndrome 7

acts_upstream_of_or_within

UniProtKB:Q99496 (PMID:22302990)

PMID:22302990

NCBI chr 2:119,434,760...119,474,665
Ensembl chr 2:119,434,760...119,474,396

Cbfa2t3

CBFA2/RUNX1 partner transcriptional co-repressor 3

involved_in

(PMID:25974097)

PMID:25974097

NCBI chr19:50,679,897...50,750,028
Ensembl chr19:50,680,729...50,749,610

Chfr

checkpoint with forkhead and ring finger domains

acts_upstream_of_or_within

(MGI:5310666|PMID:22285184)

PMID:20068069 PMID:21873635

PMID:22285184

MGI:5310666

NCBI chr12:46,504,497...46,538,104
Ensembl chr12:46,504,497...46,538,014

Clu

clusterin

involved_in

ISO
IBA
IEA
ISS

(PMID:20068069)
PMID:21873635
GO_REF:0000107
GO_REF:0000024

RGD
Ensembl
UniProt

GO_REF:0000024 GO_REF:0000107, RGD:13792537

NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315

Cop1

COP1, E3 ubiquitin ligase

involved_in

(PMID:19805145)

PMID:19805145

NCBI chr13:71,467,164...71,561,826
Ensembl chr13:71,429,961...71,538,890

Csnk1a1

casein kinase 1, alpha 1

involved_in

(PMID:11955436), (PMID:19364825)

PMID:11955436 PMID:19364825

NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271

Csnk1d

casein kinase 1, delta

involved_in

GO_REF:0000024
PMID:21873635
(MGI:3849793|PMID:19414593)

PMID:19414593 PMID:21873635

GO_REF:0000024 MGI:3849793, RGD:13792537

NCBI chr10:106,221,992...106,256,620
Ensembl chr10:106,221,992...106,256,614

Csnk1e

casein kinase 1, epsilon

involved_in

(MGI:3849793|PMID:19414593)
PMID:21873635

PMID:19414593 PMID:21873635

MGI:3849793, RGD:13792537

NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794

Dab2

DAB adaptor protein 2

involved_in

GO_REF:0000107
(PMID:12805222)

PMID:12805222

GO_REF:0000107

NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476

Dda1

DET1 and DDB1 associated 1

involved_in

PMID:21873635

GO_Central

NCBI chr16:18,156,310...18,163,938
Ensembl chr16:18,156,386...18,163,937

Ddrgk1

DDRGK domain containing 1

involved_in

(PMID:23675531)

PMID:23675531

NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680

Det1

DET1 partner of COP1 E3 ubiquitin ligase

involved_in

PMID:21873635
UniProtKB:Q8NHY2 (PMID:14739464)

PMID:14739464 PMID:21873635

NCBI chr 1:132,749,736...132,765,963
Ensembl chr 1:132,749,756...132,765,923

Dnajb2

DnaJ heat shock protein family (Hsp40) member B2

involved_in

PMID:21873635
(PMID:15936278)

PMID:15936278 PMID:21873635

NCBI chr 9:76,731,060...76,739,278
Ensembl chr 9:76,731,065...76,739,277

Dvl1

dishevelled segment polarity protein 1

involved_in

(PMID:20177058)

PMID:20177058

NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664

Fbxo22

F-box protein 22

acts_upstream_of_or_within
involved_in

(MGI:3840749|PMID:19319192)
PMID:21873635

PMID:19319192 PMID:21873635

MGI:3840749, RGD:13792537

NCBI chr 8:55,579,906...55,595,981
Ensembl chr 8:55,579,891...55,596,148

Gabarap

GABA type A receptor-associated protein

involved_in

GO_REF:0000024
(PMID:25684205)

PMID:25684205

GO_REF:0000024

NCBI chr10:54,714,834...54,717,769
Ensembl chr10:54,714,198...54,717,765

Gba

glucosylceramidase beta

involved_in

(MGI:5501380|PMID:23707074)

PMID:23707074

MGI:5501380

NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263

Gclc

glutamate-cysteine ligase, catalytic subunit

acts_upstream_of_or_within

MGI:2387010 (MGI:3695876|PMID:17189825)

PMID:17189825

MGI:3695876

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

Gsk3a

glycogen synthase kinase 3 alpha

involved_in

(PMID:25897075)

PMID:25897075

NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802

Gsk3b

glycogen synthase kinase 3 beta

acts_upstream_of_or_within
involved_in

MGI:1924375|MGI:3039600 (MGI:5437589|PMID:22660580)
(PMID:19364825), (PMID:22660580), (PMID:25897075)
GO_REF:0000107

PMID:19364825 PMID:22660580 PMID:25897075

GO_REF:0000107 MGI:5437589

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

Hspa1a

heat shock protein family A (Hsp70) member 1A

involved_in

PMID:21873635
(PMID:24613385)

PMID:24613385 PMID:21873635

NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240

Hspa1b

heat shock protein family A (Hsp70) member 1B

involved_in

PMID:21873635
(PMID:24613385)

PMID:24613385 PMID:21873635

NCBI chr20:3,870,765...3,873,221

Hspbp1

HSPA (Hsp70) binding protein 1

involved_in

(PMID:16831871)

PMID:16831871

NCBI chr 1:69,165,394...69,189,062
Ensembl chr 1:69,165,572...69,244,593

Il33

interleukin 33

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1861437|MGI:3039600 (MGI:5437589|PMID:22660580)

PMID:22660580

GO_REF:0000107 MGI:5437589

NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373

Klhl40

kelch-like family member 40

involved_in

(MGI:5700633|PMID:25940086)

PMID:25940086

MGI:5700633

NCBI chr 8:121,441,275...121,446,806
Ensembl chr 8:121,441,287...121,446,800

Lrrk2

leucine-rich repeat kinase 2

involved_in

(MGI:4454597|PMID:20457918)

PMID:20457918

MGI:4454597

NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703

Mdm2

MDM2 proto-oncogene

involved_in

(PMID:11278372)

PMID:11278372

NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915

Nkd2

NKD inhibitor of WNT signaling pathway 2

involved_in

(PMID:20177058)

PMID:20177058

NCBI chr 1:29,442,898...29,470,839
Ensembl chr 1:29,441,328...29,470,821

Nop53

NOP53 ribosome biogenesis factor

involved_in

(PMID:25818168), (PMID:27323397)
(MGI:5897550|PMID:21804542)

PMID:21804542 PMID:25818168 PMID:27323397

MGI:5897550

NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902

Nub1

negative regulator of ubiquitin-like proteins 1

involved_in

(PMID:16707496)

PMID:16707496

NCBI chr 4:10,442,917...10,473,689
Ensembl chr 4:10,442,917...10,473,694

Pabir1

PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1

involved_in

(PMID:27588481)
GO_REF:0000024

PMID:27588481

GO_REF:0000024

NCBI chr 1:222,114,988...222,116,294
Ensembl chr 1:222,112,591...222,116,396

Pias1

protein inhibitor of activated STAT, 1

involved_in

(MGI:5487503|PMID:22406621)

PMID:22406621

MGI:5487503

NCBI chr 8:63,338,150...63,451,670
Ensembl chr 8:63,338,150...63,438,905

Plk1

polo-like kinase 1

involved_in

ISO
ISS
IEA

(PMID:19473992)
GO_REF:0000024
GO_REF:0000107

RGD
UniProt
Ensembl

PMID:19473992

GO_REF:0000024 GO_REF:0000107

NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400

polo-like kinase 2

RGD

NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947

Prickle1

prickle planar cell polarity protein 1

involved_in

(PMID:17030191)
GO_REF:0000107

PMID:17030191

GO_REF:0000107

NCBI chr 7:124,639,142...124,735,027
Ensembl chr 7:124,639,142...124,658,113

Prkn

parkin RBR E3 ubiquitin protein ligase

involved_in

PMID:21873635
(MGI:5543313|PMID:23858059)

PMID:23858059 PMID:21873635

MGI:5543313, RGD:13792537

NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555

Psen1

presenilin 1

involved_in

(MGI:4887523|PMID:20208556)

NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650

Psen2

presenilin 2

involved_in

(MGI:4887523|PMID:20208556)

NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174

Psmd10

proteasome 26S subunit, non-ATPase 10

involved_in

(PMID:16023600)
GO_REF:0000024

PMID:16023600

GO_REF:0000024

NCBI chr X:104,656,809...104,665,126
Ensembl chr X:104,656,812...104,665,097

Rack1

receptor for activated C kinase 1

involved_in

GO_REF:0000024
(PMID:19785988)

PMID:19785988

GO_REF:0000024

NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975

Rad23a

RAD23 homolog A, nucleotide excision repair protein

involved_in

(PMID:26296656)

PMID:26296656

NCBI chr19:23,313,563...23,320,702
Ensembl chr19:23,314,797...23,320,695

Rbx1

ring-box 1

involved_in

UniProtKB:Q7L5Y6 (PMID:14739464)

PMID:14739464

NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051

Rchy1

ring finger and CHY zinc finger domain containing 1

involved_in

(PMID:19483087)

PMID:19483087

NCBI chr14:16,113,263...16,129,017
Ensembl chr14:16,113,224...16,129,167

Rnf14

ring finger protein 14

involved_in

PMID:21873635

GO_Central

NCBI chr18:30,131,627...30,155,686
Ensembl chr18:30,131,691...30,155,685

Rnf144a

ring finger protein 144A

involved_in

PMID:21873635

GO_Central

NCBI chr 6:42,899,767...43,019,769
Ensembl chr 6:42,903,174...43,020,012

Rnf144b

ring finger protein 144B

involved_in

PMID:21873635

GO_Central

NCBI chr17:17,431,271...17,580,687
Ensembl chr17:17,432,786...17,562,760

Rnf180

ring finger protein 180

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:3819024|PMID:18363970), (MGI:5505713|PMID:23926250)

PMID:18363970 PMID:23926250 PMID:21873635

MGI:3819024 MGI:5505713, RGD:13792537

NCBI chr 2:36,330,285...36,511,168
Ensembl chr 2:36,330,292...36,512,614

Rnf19a

ring finger protein 19A, RBR E3 ubiquitin protein ligase

involved_in

PMID:21873635

GO_Central

NCBI chr 7:67,425,833...67,465,214
Ensembl chr 7:67,425,837...67,465,222

Rnf19b

ring finger protein 19B

involved_in

PMID:21873635

GO_Central

NCBI chr 5:141,406,085...141,431,380
Ensembl chr 5:141,406,118...141,431,380

Rnf217

ring finger protein 217

involved_in

PMID:21873635

GO_Central

NCBI chr 1:26,016,668...26,108,736
Ensembl chr 1:26,015,728...26,108,736

Sh3rf1

SH3 domain containing ring finger 1

involved_in

PMID:21873635

GO_Central

NCBI chr16:28,735,522...28,901,690
Ensembl chr16:28,735,440...28,901,644

Sh3rf2

SH3 domain containing ring finger 2

involved_in

IMP
IBA
ISO

PMID:22128169
PMID:21873635
(PMID:22128169)

PMID:22128169 PMID:22128169 PMID:21873635

RGD:13673844, RGD:13792537

NCBI chr18:34,045,715...34,148,342
Ensembl chr18:34,046,879...34,146,856

Sh3rf3

SH3 domain containing ring finger 3

involved_in

PMID:21873635

GO_Central

NCBI chr20:26,765,278...27,099,261
Ensembl chr20:26,765,015...27,099,257

Sirt2

sirtuin 2

involved_in

GO_REF:0000024
(MGI:5574427|PMID:24681946)

PMID:24681946

GO_REF:0000024 MGI:5574427

NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975

Smad7

SMAD family member 7

involved_in

(PMID:11278251)
GO_REF:0000107

PMID:11278251

GO_REF:0000107

NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765

Socs5

suppressor of cytokine signaling 5

involved_in

(PMID:15590694)

PMID:15590694

NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834

Stub1

STIP1 homology and U-box containing protein 1

involved_in

(PMID:11146632)

PMID:11146632

NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046

Sumo1

small ubiquitin-like modifier 1

involved_in

(PMID:18408734)

PMID:18408734

NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761

Sumo2

small ubiquitin-like modifier 2

involved_in

(PMID:18408734)

PMID:18408734

NCBI chr10:100,771,941...100,784,503
Ensembl chr10:100,686,797...100,784,513

Taf1

TATA-box binding protein associated factor 1

involved_in

(PMID:15053879)

PMID:15053879

NCBI chr X:66,640,915...66,716,543
Ensembl chr X:66,640,982...66,716,543

Trib1

tribbles pseudokinase 1

involved_in

PMID:21873635
(MGI:4457446|PMID:20410507)

PMID:20410507 PMID:21873635

MGI:4457446, RGD:13792537

NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731

Trib2

tribbles pseudokinase 2

involved_in

(MGI:4457446|PMID:20410507)

PMID:20410507

MGI:4457446

NCBI chr 6:38,545,971...38,570,349
Ensembl chr 6:38,545,975...38,569,370

Trib3

tribbles pseudokinase 3

involved_in

PMID:21873635

GO_Central

NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497

Ube2v2

ubiquitin conjugating enzyme E2 V2

IMP

RGD

PMID:12750002

RGD:1299567

NCBI chr11:85,304,528...85,338,430
Ensembl chr11:85,304,526...85,336,369

Usp5

ubiquitin specific peptidase 5

involved_in

(PMID:19098288)

PMID:19098288

NCBI chr 4:157,619,643...157,634,711
Ensembl chr 4:157,619,643...157,634,711

valosin-containing protein

involved_in

(PMID:9452483)

PMID:9452483

NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571

Zer1

zyg-11 related, cell cycle regulator

involved_in

(PMID:31273098)

PMID:31273098

NCBI chr 3:13,369,688...13,397,524
Ensembl chr 3:13,369,688...13,397,420

Zfand2a

zinc finger AN1-type containing 2A

acts_upstream_of_or_within

MGI:3664591 (MGI:3663213|PMID:16973439)

PMID:16973439

MGI:3663213

NCBI chr12:15,161,601...15,172,679
Ensembl chr12:15,161,639...15,172,677

Zyg11b

zyg-11 family member B, cell cycle regulator

involved_in

(PMID:31273098)

PMID:31273098

NCBI chr 5:122,985,548...123,042,735
Ensembl chr 5:122,992,147...123,042,736

positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Plk3

polo-like kinase 3

involved_in

GO_REF:0000024
(PMID:20889502)

PMID:20889502

GO_REF:0000024

NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317

Sirt2

sirtuin 2

involved_in

(PMID:24681946)
GO_REF:0000024

PMID:24681946

GO_REF:0000024

NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975

positive regulation of transcription factor catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fbxw8

F-box and WD repeat domain containing 8

involved_in

(MGI:6148490|PMID:29153991)

PMID:29153991

MGI:6148490

NCBI chr12:38,426,443...38,518,712
Ensembl chr12:38,426,444...38,516,424

Mapk8

mitogen-activated protein kinase 8

involved_in

(MGI:6148490|PMID:29153991)

PMID:29153991

MGI:6148490

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

Mapk9

mitogen-activated protein kinase 9

involved_in

(MGI:6148490|PMID:29153991)

PMID:29153991

MGI:6148490

NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178

Sirt6

sirtuin 6

involved_in

(PMID:27457971)

PMID:27457971

NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914

positive regulation of ubiquitin-dependent protein catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Agbl4

AGBL carboxypeptidase 4

acts_upstream_of_or_within

MGI:5788002 (MGI:6149282|PMID:29593216)

PMID:29593216

MGI:6149282

NCBI chr 5:125,254,963...126,534,367
Ensembl chr 5:125,254,956...126,534,367

Agtpbp1

ATP/GTP binding carboxypeptidase 1

acts_upstream_of_or_within

MGI:1857523 (MGI:6149282|PMID:29593216)

PMID:29593216

MGI:6149282

NCBI chr17:5,120,540...5,238,874
Ensembl chr17:5,120,609...5,238,869

Axin1

axin 1

involved_in
acts_upstream_of_or_within

IDA
ISO

PMID:10228155
(MGI:3628833|PMID:16601693)

PMID:16601693 PMID:10228155

MGI:3628833, RGD:8553327

NCBI chr10:15,163,684...15,215,615
Ensembl chr10:15,163,684...15,215,615

Ccdc22

coiled-coil domain containing 22

involved_in

PMID:21873635
(PMID:23563313)

PMID:23563313 PMID:21873635

NCBI chr X:14,898,296...14,910,244
Ensembl chr X:14,898,296...14,910,244

Cdk5rap3

CDK5 regulatory subunit associated protein 3

NOT|involved_in

GO_REF:0000024
(PMID:16173922)

PMID:16173922

GO_REF:0000024

NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590

Clu

clusterin

involved_in

GO_REF:0000024
(PMID:20068069)

PMID:20068069

GO_REF:0000024

NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315

Disc1

DISC1 scaffold protein

acts_upstream_of_or_within

(MGI:4837265|PMID:20880836)

PMID:20880836

MGI:4837265

NCBI chr19:53,014,201...53,223,617
Ensembl chr19:53,014,616...53,219,778

Egf

epidermal growth factor

involved_in

(MGI:4887523|PMID:20208556)

NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064

Fbxo22

F-box protein 22

acts_upstream_of_or_within

(MGI:3840749|PMID:19319192)

PMID:19319192

MGI:3840749

NCBI chr 8:55,579,906...55,595,981
Ensembl chr 8:55,579,891...55,596,148

Fbxw7

F-box and WD repeat domain containing 7

involved_in

(PMID:20208556), (PMID:27238018)
(MGI:6282935|PMID:27238018)
GO_REF:0000024

PMID:20208556 PMID:27238018

GO_REF:0000024 MGI:6282935

NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941

L3mbtl3

L3MBTL histone methyl-lysine binding protein 3

involved_in

(PMID:29691401)

PMID:29691401

NCBI chr 1:18,988,763...19,089,247
Ensembl chr 1:18,990,618...19,089,263

Laptm5

lysosomal protein transmembrane 5

involved_in

(MGI:3803048|PMID:18619870), (MGI:6478861|PMID:24638062)

PMID:18619870 PMID:24638062

MGI:3803048 MGI:6478861

NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807

Pten

phosphatase and tensin homolog

involved_in

(PMID:21241890)

PMID:21241890

NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838

Ptk2

protein tyrosine kinase 2

involved_in

GO_REF:0000024
(MGI:5306293|PMID:18206965)

PMID:18206965

GO_REF:0000024 MGI:5306293

NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783

Ptk2b

protein tyrosine kinase 2 beta

involved_in

GO_REF:0000024
(MGI:4453113|PMID:19880522)

PMID:19880522

GO_REF:0000024 MGI:4453113

NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282

Rnf139

ring finger protein 139

involved_in

(PMID:25239945)

PMID:25239945

NCBI chr 7:90,439,726...90,450,911
Ensembl chr 7:90,436,621...90,488,009

Smurf1

SMAD specific E3 ubiquitin protein ligase 1

involved_in

(PMID:21454619)

PMID:21454619

NCBI chr12:9,635,009...9,726,520
Ensembl chr12:9,635,025...9,726,519

Sumo3

small ubiquitin-like modifier 3

acts_upstream_of_or_within

(MGI:3813414|PMID:18644859)

PMID:18644859

MGI:3813414

NCBI chr20:11,010,140...11,020,850
Ensembl chr20:11,007,148...11,020,877
Ensembl chr20:11,007,148...11,020,877

Trim67

tripartite motif-containing 67

acts_upstream_of_or_within

(MGI:5427306|PMID:22337885)

PMID:22337885

MGI:5427306

NCBI chr19:52,763,991...52,805,906
Ensembl chr19:52,764,387...52,800,422

valosin-containing protein

IMP

RGD

PMID:16103111

RGD:1599730

NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571

prenylated protein catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Pcyox1

prenylcysteine oxidase 1

involved_in

(PMID:10585463)
PMID:21873635

PMID:10585463 PMID:21873635

NCBI chr 4:118,832,114...118,842,951
Ensembl chr 4:118,830,638...118,842,951

Pcyox1l

prenylcysteine oxidase 1 like

involved_in

PMID:21873635

GO_Central

NCBI chr18:55,150,637...55,161,334
Ensembl chr18:55,150,650...55,161,327

Zmpste24

zinc metallopeptidase STE24

acts_upstream_of_or_within

(MGI:2137968|PMID:11399759)

PMID:11399759

MGI:2137968

NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110

proteasome-mediated ubiquitin-dependent protein catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AABR07012426.1

involved_in

PMID:21873635

GO_Central

Ensembl chr 2:180,190,557...180,217,844

AABR07034438.1

involved_in

PMID:21873635

GO_Central

Ensembl chr11:68,398,182...68,460,080

AABR07041109.1

involved_in

PMID:21873635

GO_Central

Ensembl chr X:111,788,220...111,788,672

Agap3

ArfGAP with GTPase domain, ankyrin repeat and PH domain 3

acts_upstream_of_or_within

(MGI:3616374|PMID:16461359)

PMID:16461359

MGI:3616374

NCBI chr 4:10,674,064...10,724,848
Ensembl chr 4:10,674,064...10,725,244

Akt1

AKT serine/threonine kinase 1

acts_upstream_of

(MGI:3589701|PMID:15937334)

PMID:15937334

MGI:3589701

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

Ambra1

autophagy and beclin 1 regulator 1

involved_in

(PMID:33854232), (PMID:33854235), (PMID:33854239)

PMID:33854232 PMID:33854235 PMID:33854239

NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221

Ankrd9

ankyrin repeat domain 9

involved_in

(PMID:30293565)

PMID:30293565

NCBI chr 6:130,001,914...130,008,792
Ensembl chr 6:129,998,486...130,008,923

Appbp2

amyloid beta precursor protein binding protein 2

involved_in

GO_REF:0000024
PMID:21873635
(PMID:26138980)

PMID:26138980 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr10:70,057,774...70,099,877
Ensembl chr10:70,057,774...70,099,835

Armc8

armadillo repeat containing 8

involved_in

PMID:21873635

GO_Central

NCBI chr 8:100,036,946...100,131,544
Ensembl chr 8:100,036,946...100,131,520

Arrb1

arrestin, beta 1

involved_in

(PMID:15878855)

PMID:15878855

NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061

Arrb2

arrestin, beta 2

involved_in

(PMID:15878855)

PMID:15878855

NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850

Asb2

ankyrin repeat and SOCS box-containing 2

involved_in

(PMID:21119685)
(MGI:5510317|PMID:23632887), (MGI:6718235|PMID:29374072)
GO_REF:0000024

PMID:21119685 PMID:23632887 PMID:29374072

GO_REF:0000024 MGI:5510317 MGI:6718235

NCBI chr 6:122,474,754...122,511,014
Ensembl chr 6:122,474,756...122,510,854

Atxn3

ataxin 3

involved_in

GO_REF:0000024
(MGI:5318000|PMID:21855799)

PMID:21855799

GO_REF:0000024 MGI:5318000

NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902

Aurka

aurora kinase A

acts_upstream_of

(MGI:3697244|PMID:17060449)

PMID:17060449

MGI:3697244

NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390

BAG cochaperone 6

involved_in

(MGI:5780912|PMID:26692333)

NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657

Bfar

bifunctional apoptosis regulator

involved_in

PMID:21873635
(PMID:21068390)

PMID:21068390 PMID:21873635

NCBI chr10:1,552,019...1,585,040
Ensembl chr10:1,552,072...1,585,038

Birc2

baculoviral IAP repeat-containing 2

involved_in

(PMID:11907583)

PMID:11907583

NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732

Bmal1

basic helix-loop-helix ARNT like 1

involved_in

GO_REF:0000024
(MGI:5495336|PMID:23395176)

PMID:23395176

GO_REF:0000024 MGI:5495336

NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231

Btrc

beta-transducin repeat containing E3 ubiquitin protein ligase

involved_in

(PMID:15917222)

PMID:15917222

NCBI chr 1:244,210,299...244,380,126
Ensembl chr 1:244,210,314...244,376,721

Cd2ap

CD2-associated protein

IDA

RGD

PMID:15001553

RGD:1302417

NCBI chr 9:18,086,744...18,182,744
Ensembl chr 9:18,086,984...18,182,199

Cdc34

cell division cycle 34, ubiqiutin conjugating enzyme

involved_in

(PMID:10373550), (PMID:20347421)

PMID:10373550 PMID:20347421

NCBI chr 7:10,017,588...10,023,586
Ensembl chr 7:10,017,588...10,023,186

Clec16a

C-type lectin domain containing 16A

acts_upstream_of

MGI:5648633 (MGI:5603233|PMID:24949970)

PMID:24949970

MGI:5603233

NCBI chr10:4,927,804...5,123,749
Ensembl chr10:4,928,030...5,123,578

Clock

clock circadian regulator

involved_in

IEA
ISO
ISS

GO_REF:0000107
(MGI:5495336|PMID:23395176)
GO_REF:0000024

Ensembl
RGD
UniProt

PMID:23395176

GO_REF:0000024 GO_REF:0000107 MGI:5495336

NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400

Cop1

COP1, E3 ubiquitin ligase

involved_in

(PMID:14739464)
PMID:21873635

PMID:14739464 PMID:21873635

NCBI chr13:71,467,164...71,561,826
Ensembl chr13:71,429,961...71,538,890

Crbn

cereblon

involved_in

GO_REF:0000024
(PMID:20223979)

PMID:20223979

GO_REF:0000024

NCBI chr 4:139,701,154...139,719,949
Ensembl chr 4:139,701,094...139,719,938

Ctnnb1

catenin beta 1

involved_in

(PMID:29374064)
GO_REF:0000107

PMID:29374064

GO_REF:0000107

NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111

Cul1

cullin 1

involved_in

(PMID:15145941), (PMID:34480022)

PMID:15145941 PMID:34480022

NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980

Cul3

cullin 3

involved_in
acts_upstream_of_or_within

GO_REF:0000024
(PMID:19261606), (PMID:19782033), (PMID:20389280), (PMID:25684205)
MGI:1343085 (MGI:4836774|PMID:20811152)

PMID:19261606 PMID:19782033 PMID:20389280 PMID:20811152 PMID:25684205

GO_REF:0000024 MGI:4836774

NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462

Cul4a

cullin 4A

involved_in
acts_upstream_of_or_within

(PMID:14739464)
(MGI:3777067|PMID:16467204)

PMID:14739464 PMID:16467204

MGI:3777067

NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330

Dcaf11

DDB1 and CUL4 associated factor 11

involved_in

PMID:21873635

GO_Central

NCBI chr15:29,046,744...29,057,450
Ensembl chr15:29,046,826...29,057,669

Ddb1

damage-specific DNA binding protein 1

involved_in

ISO
IEA
ISS
IBA

(PMID:14739464), (PMID:20223979)
GO_REF:0000104
GO_REF:0000024
PMID:21873635

PMID:14739464 PMID:20223979 PMID:21873635

GO_REF:0000024 GO_REF:0000104, RGD:13792537

NCBI chr 1:207,252,890...207,278,685
Ensembl chr 1:207,252,890...207,278,676

Ddit3

DNA-damage inducible transcript 3

involved_in

(PMID:17872950)
GO_REF:0000024

PMID:17872950

GO_REF:0000024

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

Derl1

derlin 1

involved_in

(MGI:5780912|PMID:26692333)

NCBI chr 7:89,404,413...89,427,095
Ensembl chr 7:89,404,417...89,427,145

Dnajb2

DnaJ heat shock protein family (Hsp40) member B2

involved_in

(PMID:21625540)

PMID:21625540

NCBI chr 9:76,731,060...76,739,278
Ensembl chr 9:76,731,065...76,739,277

Dtl

denticleless E3 ubiquitin protein ligase homolog

involved_in

PMID:21873635

GO_Central

NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890

Edem3

ER degradation enhancing alpha-mannosidase like protein 3

acts_upstream_of_or_within

(MGI:3654428|PMID:16431915)

PMID:16431915

MGI:3654428

NCBI chr13:63,858,282...63,920,538
Ensembl chr13:63,858,716...63,920,523

Epm2a

EPM2A glucan phosphatase, laforin

acts_upstream_of_or_within

MGI:2182627 (MGI:5607479|PMID:24914213)

PMID:24914213

MGI:5607479

NCBI chr 1:5,727,111...5,845,338
Ensembl chr 1:5,727,066...5,920,555

Ercc8

ERCC excision repair 8, CSA ubiquitin ligase complex subunit

involved_in

PMID:21873635
(PMID:16751180)

PMID:16751180 PMID:21873635

NCBI chr 2:39,647,393...39,686,229
Ensembl chr 2:39,647,452...39,684,859

Faf2

Fas associated factor family member 2

involved_in

(MGI:5780912|PMID:26692333)

NCBI chr17:9,947,216...9,989,474
Ensembl chr17:9,947,220...9,989,485

Fbxl17

F-box and leucine-rich repeat protein 17

involved_in

(PMID:30190310)

PMID:30190310

NCBI chr 9:102,780,573...103,206,755
Ensembl chr 9:102,782,440...103,208,950

Fbxl19

F-box and leucine-rich repeat protein 19

acts_upstream_of_or_within
involved_in

MGI:1861437|MGI:1924375 (MGI:5437589|PMID:22660580)
(PMID:23512198)
(PMID:22660580)

PMID:22660580 PMID:23512198

MGI:5437589

NCBI chr 1:182,356,899...182,380,839
Ensembl chr 1:182,360,830...182,380,083

Fbxl22

F-box and leucine-rich repeat protein 22

acts_upstream_of_or_within

(PMID:22972877)

PMID:22972877

NCBI chr 8:67,069,998...67,076,685
Ensembl chr 8:67,069,998...67,076,685

Fbxl3

F-box and leucine-rich repeat protein 3

involved_in

(MGI:3715674|PMID:17462724)

PMID:17462724

MGI:3715674

NCBI chr15:79,906,795...79,926,678
Ensembl chr15:79,906,795...79,927,867

Fbxo22

F-box protein 22

acts_upstream_of

(MGI:3840749|PMID:19319192)

PMID:19319192

MGI:3840749

NCBI chr 8:55,579,906...55,595,981
Ensembl chr 8:55,579,891...55,596,148

Fbxo45

F-box protein 45

involved_in

PMID:21873635
(MGI:4452423|PMID:19996097)

PMID:19996097 PMID:21873635

MGI:4452423, RGD:13792537

NCBI chr11:68,551,430...68,567,053
Ensembl chr11:68,551,122...68,566,800

Fbxo7

F-box protein 7

involved_in

(PMID:36646384)

PMID:36646384

NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530

Fbxo9

f-box protein 9

involved_in

(PMID:34480022)

PMID:34480022

NCBI chr 8:78,958,482...78,984,015
Ensembl chr 8:78,958,483...78,983,949

Fbxw11

F-box and WD repeat domain containing 11

involved_in

(PMID:20347421)

PMID:20347421

NCBI chr10:17,232,735...17,330,584
Ensembl chr10:17,227,181...17,330,571

Fbxw5

F-box and WD repeat domain containing 5

involved_in

(PMID:18381890)
GO_REF:0000024

PMID:18381890

GO_REF:0000024

NCBI chr 3:8,322,543...8,327,092
Ensembl chr 3:8,322,543...8,327,092

Fbxw7

F-box and WD repeat domain containing 7

involved_in

IBA
ISO
ISS

PMID:21873635
(PMID:35395208)
GO_REF:0000024
(PMID:25897075)

PMID:25897075 PMID:35395208 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941

Fem1b

fem-1 homolog B

involved_in

GO_REF:0000024
(PMID:24076122)

PMID:24076122

GO_REF:0000024

NCBI chr 8:63,265,301...63,278,577
Ensembl chr 8:63,265,301...63,278,577

Fem1c

fem-1 homolog C

involved_in

(PMID:26138980)

NCBI chr18:39,232,900...39,258,692
Ensembl chr18:39,232,900...39,258,692

Gba

glucosylceramidase beta

acts_upstream_of_or_within

(MGI:5501380|PMID:23707074)

PMID:23707074

MGI:5501380

NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263

Gid4

GID complex subunit 4

involved_in

PMID:21873635

GO_Central

NCBI chr10:45,221,210...45,247,627
Ensembl chr10:45,245,754...45,247,621
Ensembl chr10:45,245,754...45,247,621

Gid8

GID complex subunit 8 homolog

involved_in

PMID:21873635

GO_Central

NCBI chr 3:167,826,006...167,836,759
Ensembl chr 3:167,826,060...167,834,814

Gsk3a

glycogen synthase kinase 3 alpha

involved_in

GO_REF:0000024
(MGI:5514334|PMID:16543145)

PMID:16543145

GO_REF:0000024 MGI:5514334

NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802

Hectd1

HECT domain E3 ubiquitin protein ligase 1

involved_in

PMID:21873635

GO_Central

NCBI chr 6:69,181,429...69,267,803
Ensembl chr 6:69,181,436...69,268,053

Hectd3

HECT domain E3 ubiquitin protein ligase 3

involved_in

(PMID:18194665)
PMID:21873635

PMID:18194665 PMID:21873635

NCBI chr 5:130,469,841...130,479,802
Ensembl chr 5:130,469,840...130,478,561

Herc2

HECT and RLD domain containing E3 ubiquitin protein ligase 2

involved_in

(MGI:5780912|PMID:26692333)

NCBI chr 1:106,904,789...107,110,997
Ensembl chr 1:106,880,084...107,108,134

Ifi27

interferon, alpha-inducible protein 27

involved_in

(PMID:27194766)

PMID:27194766

NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294

Itch

itchy E3 ubiquitin protein ligase

involved_in

(PMID:22009753)
PMID:21873635

PMID:22009753 PMID:21873635

NCBI chr 3:143,642,348...143,733,745
Ensembl chr 3:143,645,637...143,733,543

Kat5

lysine acetyltransferase 5

involved_in

(PMID:18397884)

PMID:18397884

NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458

Kat7

lysine acetyltransferase 7

involved_in

GO_REF:0000041

GO_REF:0000041

NCBI chr10:80,221,519...80,255,590
Ensembl chr10:80,221,524...80,255,567

Kbtbd6

kelch repeat and BTB domain containing 6

involved_in

(PMID:25684205)

PMID:25684205

NCBI chr15:54,848,285...54,850,042
Ensembl chr15:54,848,446...54,850,453

Kbtbd7

kelch repeat and BTB domain containing 7

involved_in

(PMID:25684205)

PMID:25684205

NCBI chr15:54,806,878...54,811,457
Ensembl chr15:54,806,873...54,811,687

Kctd10

potassium channel tetramerization domain containing 10

involved_in

IBA
ISS

PMID:21873635
GO_REF:0000024

GO_REF:0000024, RGD:13792537

NCBI chr12:42,230,159...42,248,792
Ensembl chr12:42,230,269...42,248,783

Kctd13

potassium channel tetramerization domain containing 13

involved_in

(PMID:19782033)

PMID:19782033

NCBI chr 1:181,534,534...181,552,843
Ensembl chr 1:181,534,515...181,552,881

Kctd17

potassium channel tetramerization domain containing 17

involved_in

(PMID:25270598)
PMID:21873635

PMID:25270598 PMID:21873635

NCBI chr 7:109,979,060...110,009,091
Ensembl chr 7:109,979,060...110,008,927

Kctd2

potassium channel tetramerization domain containing 2

involved_in

PMID:21873635

GO_Central

NCBI chr10:100,663,013...100,674,756
Ensembl chr10:100,662,884...100,674,336

Kctd5

potassium channel tetramerization domain containing 5

involved_in

PMID:21873635

GO_Central

NCBI chr10:13,079,216...13,105,197
Ensembl chr10:13,079,214...13,105,209

Kif14

kinesin family member 14

involved_in

(PMID:24854087)

PMID:24854087

NCBI chr13:47,926,975...47,990,598
Ensembl chr13:47,927,044...47,989,164

Klhdc2

kelch domain containing 2

involved_in

(PMID:26138980)
GO_REF:0000024

GO_REF:0000024

NCBI chr 6:87,777,183...87,791,609
Ensembl chr 6:87,777,183...87,804,187

Klhdc3

kelch domain containing 3

involved_in

(PMID:26138980)
GO_REF:0000024

GO_REF:0000024

NCBI chr 9:14,302,345...14,308,736
Ensembl chr 9:14,302,354...14,308,736

Klhl20

kelch-like family member 20

involved_in

(PMID:20389280)
PMID:21873635
GO_REF:0000024

PMID:20389280 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr13:73,363,451...73,408,346
Ensembl chr13:73,363,455...73,408,337

Klhl22

kelch-like family member 22

involved_in

GO_REF:0000024
PMID:21873635
(PMID:29769719)

PMID:29769719 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr11:83,190,891...83,231,746
Ensembl chr11:83,190,891...83,231,770

Klhl40

kelch-like family member 40

acts_upstream_of

(MGI:5586592|PMID:24960163)

PMID:24960163

MGI:5586592

NCBI chr 8:121,441,275...121,446,806
Ensembl chr 8:121,441,287...121,446,800

Klhl42

kelch-like family, member 42

involved_in

(PMID:19261606)

PMID:19261606

NCBI chr 4:179,999,655...180,027,283
Ensembl chr 4:180,004,580...180,027,283

Maea

macrophage erythroblast attacher, E3 ubiquitin ligase

involved_in

PMID:21873635
GO_REF:0000002

GO_REF:0000002, RGD:13792537

NCBI chr14:77,357,261...77,390,683
Ensembl chr14:77,357,264...77,390,671

Marchf6

membrane associated ring-CH-type finger 6

involved_in

(PMID:24449766)

PMID:24449766

NCBI chr 2:82,455,686...82,532,917
Ensembl chr 2:82,455,689...82,532,910

Mta1

metastasis associated 1

involved_in

(PMID:19805145)
GO_REF:0000024

PMID:19805145

GO_REF:0000024

NCBI chr 6:132,178,608...132,217,641
Ensembl chr 6:132,178,853...132,217,641

Mtm1

myotubularin 1

acts_upstream_of

MGI:2450997 (MGI:5510937|PMID:23695157)

PMID:23695157

MGI:5510937

NCBI chr 6:488,691...506,964
Ensembl chr 6:488,969...506,860

Naglu

N-acetyl-alpha-glucosaminidase

acts_upstream_of_or_within

MGI:1934018 (MGI:4367540|PMID:19386237)

PMID:19386237

MGI:4367540

NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972

Nedd4l

NEDD4 like E3 ubiquitin protein ligase

involved_in

(PMID:21463633)

PMID:21463633

NCBI chr18:58,393,759...58,726,709
Ensembl chr18:58,393,509...58,723,137

Nfe2l2

NFE2 like bZIP transcription factor 2

involved_in

(PMID:15983046)
GO_REF:0000024

PMID:15983046

GO_REF:0000024

NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737

Nhlrc1

NHL repeat containing E3 ubiquitin protein ligase 1

involved_in
acts_upstream_of_or_within

IBA
ISO
ISS

PMID:21873635
MGI:3808349 (MGI:5607479|PMID:24914213)
GO_REF:0000024
(PMID:15930137)

PMID:15930137 PMID:24914213 PMID:21873635

GO_REF:0000024 MGI:5607479, RGD:13792537

NCBI chr17:17,674,375...17,675,565
Ensembl chr17:17,674,319...17,677,148

Nhlrc3

NHL repeat containing 3

involved_in

PMID:21873635

GO_Central

NCBI chr 2:137,527,843...137,542,258
Ensembl chr 2:137,530,012...137,534,879
Ensembl chr 2:137,530,012...137,534,879

Nsfl1c

NSFL1 cofactor

involved_in

PMID:21873635

GO_Central

NCBI chr 3:139,978,306...140,002,876
Ensembl chr 3:139,978,301...140,002,870

Otud5

OTU deubiquitinase 5

acts_upstream_of_or_within

MGI:2386448|MGI:5752247 (MGI:5621075|PMID:25470037)

PMID:25470037

MGI:5621075

NCBI chr X:14,626,173...14,659,331
Ensembl chr X:14,626,164...14,659,573

Pbk

PDZ binding kinase

acts_upstream_of

MGI:5293435 (MGI:5293269|PMID:21715333)

PMID:21715333

MGI:5293269

NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014

Pcbp2

poly(rC) binding protein 2

involved_in

(PMID:19881509)

PMID:14741369 PMID:21873635

PMID:19881509

NCBI chr 7:133,605,480...133,631,312
Ensembl chr 7:133,605,573...133,629,863

Pcnp

PEST proteolytic signal containing nuclear protein

involved_in

ISS
IEA
ISO
IBA

GO_REF:0000024
GO_REF:0000107
(PMID:14741369)
PMID:21873635

HGNC-UCL
Ensembl
RGD

GO_REF:0000024 GO_REF:0000107, RGD:13792537

NCBI chr11:44,592,766...44,607,372
Ensembl chr11:44,592,742...44,607,348

Peli1

pellino E3 ubiquitin protein ligase 1

involved_in

(PMID:29883609)

PMID:29883609

NCBI chr14:95,254,274...95,309,168
Ensembl chr14:95,254,589...95,308,285

Pja2

praja ring finger ubiquitin ligase 2

involved_in

(PMID:33934390)

PMID:33934390

NCBI chr 9:103,956,678...104,006,763
Ensembl chr 9:103,956,678...104,006,783

Plaa

phospholipase A2, activating protein

involved_in

PMID:21873635

GO_Central

NCBI chr 5:109,428,600...109,460,373
Ensembl chr 5:109,428,265...109,460,282

Pml

PML nuclear body scaffold

involved_in

(PMID:22406621)

PMID:22406621

NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971

Pmp22

peripheral myelin protein 22

acts_upstream_of_or_within

MGI:1856217 (MGI:3574149|PMID:15748170)

PMID:15748170

MGI:3574149

NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714

Ppp2cb

protein phosphatase 2 catalytic subunit beta

acts_upstream_of_or_within

(MGI:3694309|PMID:16717086)

PMID:16717086

MGI:3694309

NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576

Ppp2r5c

protein phosphatase 2, regulatory subunit B', gamma

acts_upstream_of_or_within

(PMID:16717086)

PMID:16717086

NCBI chr 6:129,461,689...129,598,344
Ensembl chr 6:129,461,648...129,598,346

Prame

PRAME nuclear receptor transcriptional regulator

involved_in

(PMID:26138980)

NCBI chr X:98,567,994...98,574,654
Ensembl chr X:98,569,415...98,572,096

Pramef27

PRAME family member 27

involved_in

(PMID:26138980)

NCBI chr 5:155,752,765...155,759,663
Ensembl chr 5:155,756,015...155,759,663

Prkn

parkin RBR E3 ubiquitin protein ligase

involved_in

PMID:11439185 PMID:21376232

(PMID:11439185), (PMID:21376232)
GO_REF:0000024

RGD
ParkinsonsUK-UCL

GO_REF:0000024

NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555

Psma5

proteasome 20S subunit alpha 5

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:195,896,365...195,919,731

Psmb3

proteasome 20S subunit beta 3

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521

Psmb5

proteasome 20S subunit beta 5

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:3047032|PMID:15198663)

PMID:15198663

GO_REF:0000107 MGI:3047032

NCBI chr15:28,072,772...28,077,367
Ensembl chr15:28,072,781...28,077,440

Psmc1

proteasome 26S subunit, ATPase 1

involved_in

PMID:21873635

GO_Central

NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123

Psmc2

proteasome 26S subunit, ATPase 2

involved_in

PMID:21873635

GO_Central

NCBI chr 4:13,255,851...13,270,102
Ensembl chr 4:13,255,856...13,270,185

Psmc3

proteasome 26S subunit, ATPase 3

involved_in

PMID:21873635

GO_Central

NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358

Psmc4

proteasome 26S subunit, ATPase 4

involved_in

PMID:21873635

GO_Central

NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494

Psmc5

proteasome 26S subunit, ATPase 5

involved_in

(PMID:12110588)
PMID:21873635
GO_REF:0000024

PMID:12110588 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135

Psmd1

proteasome 26S subunit, non-ATPase 1

involved_in

PMID:21873635

GO_Central

NCBI chr 9:86,709,714...86,785,213
Ensembl chr 9:86,709,947...86,785,211

Psmd12

proteasome 26S subunit, non-ATPase 12

RGD

PMID:9426256

RGD:8693626

NCBI chr10:92,438,223...92,457,323
Ensembl chr10:92,438,298...92,457,287

Psmd14

proteasome 26S subunit, non-ATPase 14

involved_in

PMID:21873635

GO_Central

NCBI chr 3:46,254,338...46,347,076
Ensembl chr 3:46,254,330...46,347,076

Psmd2

proteasome 26S subunit ubiquitin receptor, non-ATPase 2

involved_in

PMID:21873635

GO_Central

NCBI chr11:80,248,364...80,258,991
Ensembl chr11:80,248,364...80,259,043

Psmd4

proteasome 26S subunit ubiquitin receptor, non-ATPase 4

involved_in

PMID:21873635

GO_Central

NCBI chr 2:182,598,934...182,608,250
Ensembl chr 2:182,598,934...182,608,194

Psmd6

proteasome 26S subunit, non-ATPase 6

involved_in

PMID:21873635

GO_Central

NCBI chr15:11,102,208...11,112,180
Ensembl chr15:11,102,180...11,205,620

Psmd7

proteasome 26S subunit, non-ATPase 7

involved_in

PMID:21873635

GO_Central

NCBI chr19:35,494,317...35,501,605
Ensembl chr19:35,494,316...35,501,588

Psmd8

proteasome 26S subunit, non-ATPase 8

involved_in

PMID:21873635

GO_Central

NCBI chr 1:84,474,377...84,481,209
Ensembl chr 1:84,474,378...84,481,209

Psmf1

proteasome inhibitor subunit 1

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr 3:140,235,371...140,260,546
Ensembl chr 3:140,235,373...140,260,546

Rad23a

RAD23 homolog A, nucleotide excision repair protein

involved_in

PMID:21873635

GO_Central

NCBI chr19:23,313,563...23,320,702
Ensembl chr19:23,314,797...23,320,695

Rad23b

RAD23 homolog B, nucleotide excision repair protein

involved_in

PMID:21873635
GO_REF:0000104

GO_REF:0000104, RGD:13792537

NCBI chr 5:70,090,232...70,128,340
Ensembl chr 5:70,090,232...70,128,319

Rbck1

RANBP2-type and C3HC4-type zinc finger containing 1

involved_in

IEA
IBA
ISO

GO_REF:0000107
PMID:21873635
(PMID:17449468)

PMID:17449468 PMID:21873635

GO_REF:0000107, RGD:13792537

NCBI chr 3:140,789,079...140,806,017
Ensembl chr 3:140,789,080...140,806,005

Rbx1

ring-box 1

involved_in

(PMID:20389280), (PMID:34480022)

PMID:20389280 PMID:34480022

NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051

Rffl

ring finger and FYVE-like domain containing E3 ubiquitin protein ligase

involved_in

GO_REF:0000024
PMID:21873635
(PMID:18382127), (PMID:22609986)

PMID:18382127 PMID:22609986 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr10:67,740,711...67,803,694
Ensembl chr10:67,740,712...67,824,434

RGD1563667

similar to TDPOZ3

involved_in

PMID:21873635

GO_Central

NCBI chr 2:181,879,563...181,953,471
Ensembl chr 2:181,879,555...182,004,263

RGD1564313

similar to TDPOZ3

involved_in

PMID:21873635

GO_Central

NCBI chr 2:179,520,448...179,521,542
Ensembl chr 2:179,520,409...179,521,542

RGD1564425

similar to Proteasome subunit beta type 3 (Proteasome theta chain)

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr 3:118,672,316...118,672,933
Ensembl chr 3:118,672,233...118,672,933

RGD1566337

similar to TDPOZ2

involved_in

PMID:21873635

GO_Central

NCBI chr 2:179,417,655...179,418,749
Ensembl chr 2:179,417,655...179,418,749

Rhobtb3

Rho-related BTB domain containing 3

involved_in

PMID:21873635

GO_Central

NCBI chr 2:5,363,388...5,419,164
Ensembl chr 2:5,363,388...5,419,041

Rmnd5a

required for meiotic nuclear division 5 homolog A

involved_in

PMID:21873635

GO_Central

NCBI chr 4:103,375,846...103,432,890
Ensembl chr 4:103,379,908...103,433,051

Rmnd5b

required for meiotic nuclear division 5 homolog B

involved_in

PMID:21873635

GO_Central

NCBI chr10:35,881,250...35,892,322
Ensembl chr10:35,881,268...35,892,265

Rnf122

ring finger protein 122

involved_in

(PMID:20553626)

PMID:20553626

NCBI chr16:61,009,879...61,027,520
Ensembl chr16:61,009,879...61,027,448

Rnf126

ring finger protein 126

involved_in

(PMID:24981174)

PMID:24981174

NCBI chr 7:9,939,359...9,946,963
Ensembl chr 7:9,938,229...9,946,738

Rnf186

ring finger protein 186

involved_in

(PMID:23896122)
PMID:21873635

PMID:23896122 PMID:21873635

NCBI chr 5:151,210,492...151,211,716
Ensembl chr 5:151,210,492...151,211,716

Rnf187

ring finger protein 187

involved_in

(PMID:20852630)
GO_REF:0000024

PMID:20852630

GO_REF:0000024

NCBI chr10:43,709,493...43,715,392
Ensembl chr10:43,702,357...43,716,157

Rnf216

ring finger protein 216

involved_in

(PMID:19893624)

PMID:19893624

NCBI chr12:11,454,752...11,576,305
Ensembl chr12:11,454,797...11,576,304

Rnf34

ring finger protein 34

involved_in

(PMID:15069192), (PMID:22064484), (PMID:25012219)
PMID:21873635
(MGI:5582154|PMID:22064484)
GO_REF:0000024

PMID:15069192 PMID:22064484 PMID:25012219 PMID:21873635

GO_REF:0000024 MGI:5582154, RGD:13792537

NCBI chr12:33,703,655...33,724,606
Ensembl chr12:33,703,673...33,724,586

Rnf4

ring finger protein 4

involved_in

ISO
IEA
ISS

(PMID:18408734), (PMID:20212317), (PMID:20943951)
GO_REF:0000107
GO_REF:0000024

RGD
Ensembl
UniProt

PMID:18408734 PMID:20212317 PMID:20943951

GO_REF:0000024 GO_REF:0000107

NCBI chr14:76,401,292...76,423,270
Ensembl chr14:76,401,299...76,422,566

Senp1

SUMO specific peptidase 1

acts_upstream_of

MGI:3818522 (MGI:3818351|PMID:17981124)

PMID:17981124

MGI:3818351

NCBI chr 7:129,163,173...129,226,766
Ensembl chr 7:129,165,774...129,221,598

Sh3bgrl1

SH3 domain binding glutamate rich protein like 1

involved_in

(PMID:34331014)

PMID:34331014

NCBI chr X:74,167,029...74,263,783
Ensembl chr X:74,166,871...74,263,783

Sharpin

SHANK-associated RH domain interactor

involved_in

PMID:21873635

GO_Central

NCBI chr 7:108,070,681...108,075,012
Ensembl chr 7:108,070,687...108,074,955

Siah1

siah E3 ubiquitin protein ligase 1

involved_in

ISS
ISO
IBA

GO_REF:0000024
(PMID:28546513), (PMID:33591310)
PMID:21873635
(MGI:4441266|PMID:16615911), (MGI:6867117|PMID:28546513)

PMID:16615911 PMID:28546513 PMID:33591310 PMID:21873635

GO_REF:0000024 MGI:4441266 MGI:6867117, RGD:13792537

NCBI chr19:20,378,908...20,402,512
Ensembl chr19:20,378,439...20,403,808

Siah2

siah E3 ubiquitin protein ligase 2

involved_in

PMID:21873635

GO_Central

NCBI chr 2:142,913,924...142,931,752
Ensembl chr 2:142,914,003...142,931,950

Siah3

siah E3 ubiquitin protein ligase family member 3

involved_in

PMID:21873635

GO_Central

NCBI chr15:50,770,963...50,834,278
Ensembl chr15:50,770,871...50,834,487

Sirt1

sirtuin 1

involved_in

(PMID:21841822)

PMID:21841822

NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260

Sirt2

sirtuin 2

involved_in

(PMID:21841822)
GO_REF:0000024

PMID:21841822

GO_REF:0000024

NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975

Skp1

S-phase kinase-associated protein 1

involved_in

(PMID:15145941), (PMID:34480022)

PMID:15145941 PMID:34480022

NCBI chr10:36,401,987...36,417,066
Ensembl chr10:36,402,153...36,417,388

Skp2

S-phase kinase associated protein 2

involved_in

(PMID:27194766)

PMID:27194766

NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338

Smurf1

SMAD specific E3 ubiquitin protein ligase 1

involved_in

(PMID:11278251)
PMID:21873635

PMID:11278251 PMID:21873635

NCBI chr12:9,635,009...9,726,520
Ensembl chr12:9,635,025...9,726,519

Smurf2

SMAD specific E3 ubiquitin protein ligase 2

involved_in

PMID:21873635

GO_Central

NCBI chr10:91,761,798...91,862,485
Ensembl chr10:91,761,807...91,862,488

Spop

speckle type BTB/POZ protein

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:1347360 (MGI:4836774|PMID:20811152)
(PMID:22085717), (PMID:32109420)

PMID:20811152 PMID:22085717 PMID:32109420 PMID:21873635

MGI:4836774, RGD:13792537

NCBI chr10:80,358,121...80,438,983
Ensembl chr10:80,358,124...80,483,955

Spopfm2l1

speckle-type BTB/POZ protein family member 2 like 1

involved_in

PMID:21873635

GO_Central

NCBI chr 2:181,837,103...181,844,470
Ensembl chr 2:181,837,105...181,953,508

Spopl

speckle type BTB/POZ protein like

involved_in

PMID:21873635
(PMID:22632832)

PMID:22632832 PMID:21873635

NCBI chr 3:6,074,681...6,148,508
Ensembl chr 3:6,078,310...6,108,794

Spsb1

splA/ryanodine receptor domain and SOCS box containing 1

involved_in

PMID:21873635

GO_Central

NCBI chr 5:160,358,292...160,418,541
Ensembl chr 5:160,358,308...160,418,468

Spsb2

splA/ryanodine receptor domain and SOCS box containing 2

involved_in

PMID:21873635

GO_Central

NCBI chr 4:157,612,921...157,615,293
Ensembl chr 4:157,613,401...157,615,284

Spsb3

splA/ryanodine receptor domain and SOCS box containing 3

involved_in

PMID:21873635

GO_Central

NCBI chr10:13,907,175...13,912,841
Ensembl chr10:13,907,253...13,912,841

Spsb4

splA/ryanodine receptor domain and SOCS box containing 4

involved_in

PMID:21873635

GO_Central

NCBI chr 8:97,536,519...97,609,757
Ensembl chr 8:97,536,520...97,609,787

Stub1

STIP1 homology and U-box containing protein 1

involved_in

(PMID:15781469), (PMID:24613385), (PMID:29883609)
(MGI:5318000|PMID:21855799)
PMID:21873635

PMID:15781469 PMID:21855799 PMID:24613385 PMID:29883609 PMID:21873635

MGI:5318000, RGD:13792537

NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046

Tbl1x

transducin (beta)-like 1 X-linked

acts_upstream_of_or_within

(MGI:3032799|PMID:14980219)

PMID:14980219

MGI:3032799

NCBI chr X:41,574,558...41,731,117
Ensembl chr X:41,576,047...41,731,101

Tbl1xr1

TBL1X/Y related 1

acts_upstream_of_or_within

(MGI:3032799|PMID:14980219)

PMID:14980219

MGI:3032799

NCBI chr 2:104,788,950...104,929,055
Ensembl chr 2:104,801,721...104,929,055

Tbx21

T-box transcription factor 21

involved_in

(MGI:5543347|PMID:23616576)

PMID:23616576

MGI:5543347

NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831

Tdpoz1-ps5

TD and POZ domain containing 1, pseudogene 5

involved_in

PMID:21873635

GO_Central

NCBI chr 2:181,807,922...181,810,233
Ensembl chr 2:181,808,333...181,809,463

Tnfaip1

TNF alpha induced protein 1

involved_in

ISO
ISS
IBA

(PMID:19782033)
GO_REF:0000024
PMID:21873635

PMID:19782033 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr10:63,417,774...63,432,466
Ensembl chr10:63,417,775...63,432,466

Topors

TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase

involved_in

(PMID:18077445)

PMID:18077445

NCBI chr 5:55,388,033...55,399,937
Ensembl chr 5:55,387,632...55,399,937

Trim13

tripartite motif-containing 13

involved_in

(PMID:17314412), (PMID:21333377)

PMID:17314412 PMID:21333377

NCBI chr15:35,733,548...35,772,676
Ensembl chr15:35,734,107...35,772,677

Trim2

tripartite motif-containing 2

involved_in

PMID:21873635

GO_Central

NCBI chr 2:169,500,628...169,652,855
Ensembl chr 2:169,500,634...169,652,927

Trim3

tripartite motif-containing 3

involved_in

PMID:21873635

GO_Central

NCBI chr 1:159,950,921...159,973,600
Ensembl chr 1:159,944,908...159,973,600

Trim38

tripartite motif containing 38

acts_upstream_of_or_within

(MGI:5441682|PMID:22539786)

PMID:22539786

MGI:5441682

NCBI chr17:41,351,857...41,365,021

Trim63

tripartite motif containing 63

acts_upstream_of_or_within

(MGI:3525851|PMID:15601779)

PMID:15601779

MGI:3525851

NCBI chr 5:146,533,492...146,547,332
Ensembl chr 5:146,533,507...146,547,322

Trim71

tripartite motif containing 71

involved_in

PMID:21873635

GO_Central

NCBI chr 8:114,193,439...114,250,807
Ensembl chr 8:114,199,187...114,250,807

Trim72

tripartite motif containing 72

acts_upstream_of_or_within
involved_in

(MGI:5602876|PMID:23965929)
PMID:21873635

PMID:23965929 PMID:21873635

MGI:5602876, RGD:13792537

NCBI chr 1:182,613,753...182,621,613
Ensembl chr 1:182,613,712...182,621,606

Trim9

tripartite motif-containing 9

involved_in

GO_REF:0000024
(PMID:20085810)

PMID:20085810

GO_REF:0000024

NCBI chr 6:88,756,824...88,856,588
Ensembl chr 6:88,757,303...88,856,542

Trip12

thyroid hormone receptor interactor 12

involved_in

PMID:21873635

GO_Central

NCBI chr 9:85,916,691...86,043,312
Ensembl chr 9:85,916,691...86,051,403

Ube2a

ubiquitin-conjugating enzyme E2A

involved_in

PMID:21873635

GO_Central

NCBI chr X:116,114,339...116,125,076
Ensembl chr X:116,113,875...116,125,070

Ube2b

ubiquitin-conjugating enzyme E2B

involved_in

(PMID:10373550)
PMID:21873635

PMID:10373550 PMID:21873635

NCBI chr10:36,248,434...36,263,379
Ensembl chr10:36,248,438...36,264,665

Ube2d3

ubiquitin-conjugating enzyme E2D 3

involved_in
acts_upstream_of_or_within

GO_REF:0000024
(MGI:3525851|PMID:15601779)
(PMID:20347421)

PMID:15601779 PMID:20347421

GO_REF:0000024 MGI:3525851

NCBI chr 2:223,868,397...223,899,606
Ensembl chr 2:223,868,730...223,898,081

Ube2g1

ubiquitin-conjugating enzyme E2G 1

involved_in

PMID:21873635

GO_Central

NCBI chr10:57,225,963...57,306,748
Ensembl chr10:57,225,952...57,308,568

Ube2h

ubiquitin-conjugating enzyme E2H

acts_upstream_of_or_within

MGI:3612190 (MGI:5602876|PMID:23965929)

PMID:23965929

MGI:5602876

NCBI chr 4:58,834,674...58,930,156
Ensembl chr 4:58,834,674...58,930,156

Ube2i

ubiquitin-conjugating enzyme E2I

IMP

RGD

PMID:9013644

RGD:730030

NCBI chr10:14,277,749...14,294,681
Ensembl chr10:69,701,618...69,702,443
Ensembl chr10:69,701,618...69,702,443

Ube2k

ubiquitin-conjugating enzyme E2K

involved_in

PMID:21873635

GO_Central

NCBI chr14:42,658,016...42,718,899
Ensembl chr14:42,658,016...42,718,630

Ube2w

ubiquitin-conjugating enzyme E2W

involved_in

GO_REF:0000024
(MGI:5318000|PMID:21855799)

PMID:21855799

GO_REF:0000024 MGI:5318000

NCBI chr 5:2,690,742...2,754,491
Ensembl chr 5:2,690,763...2,814,965

Ube3d

ubiquitin protein ligase E3D

involved_in

PMID:21873635

GO_Central

NCBI chr 8:87,245,503...87,413,104
Ensembl chr 8:87,245,589...87,413,057

Ube4b

ubiquitination factor E4B

acts_upstream_of_or_within

(PMID:23509263)

PMID:23509263

NCBI chr 5:159,766,829...159,870,509
Ensembl chr 5:159,766,829...159,870,509

Ubxn11

UBX domain protein 11

involved_in

PMID:21873635

GO_Central

NCBI chr 5:146,329,666...146,353,529
Ensembl chr 5:146,329,842...146,353,526

Ubxn2a

UBX domain protein 2A

involved_in

PMID:21873635

GO_Central

NCBI chr 6:27,884,253...27,912,709
Ensembl chr 6:27,884,680...27,912,649

Ubxn2b

UBX domain protein 2B

involved_in

PMID:21873635

GO_Central

NCBI chr 5:19,303,634...19,333,181
Ensembl chr 5:19,303,682...19,326,849

Usp14

ubiquitin specific peptidase 14

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr18:1,018,111...1,057,727
Ensembl chr18:1,019,400...1,057,519

Usp44

ubiquitin specific peptidase 44

involved_in

(MGI:5448515|PMID:21853124)

PMID:21853124

MGI:5448515

NCBI chr 7:28,364,169...28,412,039
Ensembl chr 7:28,364,033...28,410,053

valosin-containing protein

involved_in

GO_REF:0000024
(MGI:5780912|PMID:26692333)
(PMID:20104022)

PMID:20104022 PMID:26692333

GO_REF:0000024 MGI:5780912

NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571

Wdr26

WD repeat domain 26

involved_in

PMID:21873635

GO_Central

NCBI chr13:92,930,282...92,972,061
Ensembl chr13:92,930,285...92,977,295

Wwp1

WW domain containing E3 ubiquitin protein ligase 1

involved_in

(MGI:4820705|PMID:19561640), (MGI:4820708|PMID:19047365)
PMID:21873635

PMID:19047365 PMID:19561640 PMID:21873635

MGI:4820705 MGI:4820708, RGD:13792537

NCBI chr 5:33,092,379...33,185,887
Ensembl chr 5:33,098,494...33,186,046

Wwp2

WW domain containing E3 ubiquitin protein ligase 2

involved_in

(PMID:19274063)
PMID:21873635
(MGI:4821930|PMID:19997087)

PMID:19274063 PMID:19997087 PMID:21873635

MGI:4821930, RGD:13792537

NCBI chr19:35,346,826...35,471,251
Ensembl chr19:35,346,814...35,472,699

Zfand2a

zinc finger AN1-type containing 2A

involved_in

PMID:21873635

GO_Central

NCBI chr12:15,161,601...15,172,679
Ensembl chr12:15,161,639...15,172,677

Zfand2b

zinc finger AN1-type containing 2B

involved_in

(PMID:26692333)
PMID:21873635
(MGI:5780912|PMID:26692333)

PMID:26692333 PMID:21873635

MGI:5780912, RGD:13792537

NCBI chr 9:76,665,466...76,668,447
Ensembl chr 9:76,665,546...76,668,445

Znrf1

zinc and ring finger 1

involved_in

(MGI:5306704|PMID:22057101)
PMID:21873635

PMID:22057101 PMID:21873635

MGI:5306704, RGD:13792537

NCBI chr19:39,496,886...39,581,600
Ensembl chr19:39,496,527...39,580,969

Znrf2

zinc and ring finger 2

involved_in

PMID:21873635

GO_Central

NCBI chr 4:83,950,406...84,032,676
Ensembl chr 4:83,949,309...84,027,818

Zswim8

zinc finger, SWIM-type containing 8

involved_in

(PMID:33184234)

PMID:33184234

NCBI chr15:3,573,780...3,589,501
Ensembl chr15:3,573,780...3,589,487

protein arginylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ate1

arginyltransferase 1

acts_upstream_of_or_within
involved_in

(MGI:3587444|PMID:16002466)
PMID:21873635

PMID:16002466 PMID:21873635

MGI:3587444, RGD:13792537

NCBI chr 1:184,961,548...185,081,112
Ensembl chr 1:184,963,562...185,080,908

C10h17orf97

similar to human chromosome 17 open reading frame 97

involved_in

PMID:21873635
(MGI:5608602|PMID:25369936)

PMID:25369936 PMID:21873635

MGI:5608602, RGD:13792537

NCBI chr10:60,872,529...60,876,191
Ensembl chr10:60,872,511...60,876,204

protein deubiquitination involved in ubiquitin-dependent protein catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Otud7a

OTU deubiquitinase 7A

involved_in

PMID:21873635

GO_Central

NCBI chr 1:117,064,428...117,388,217
Ensembl chr 1:117,064,496...117,386,480

Otud7b

OTU deubiquitinase 7B

involved_in

PMID:21873635

GO_Central

NCBI chr 2:183,661,955...183,722,584
Ensembl chr 2:183,662,163...183,718,674

Tnfaip3

TNF alpha induced protein 3

involved_in

PMID:21873635

GO_Central

NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282

Usp28

ubiquitin specific peptidase 28

involved_in

(PMID:24623306)

PMID:24623306

NCBI chr 8:49,325,766...49,386,229
Ensembl chr 8:49,325,867...49,386,229

Usp9x

ubiquitin specific peptidase 9, X-linked

involved_in

(PMID:29626158)
(MGI:6157201|PMID:29626158)

PMID:29626158

MGI:6157201

NCBI chr X:9,588,825...9,726,993
Ensembl chr X:9,588,825...9,696,711

Zranb1

zinc finger RANBP2-type containing 1

involved_in

(PMID:18281465)
PMID:21873635

PMID:18281465 PMID:21873635

NCBI chr 1:187,725,354...187,780,129
Ensembl chr 1:187,724,320...187,779,655

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ptpn23

protein tyrosine phosphatase, non-receptor type 23

involved_in

PMID:21873635

GO_Central

NCBI chr 8:110,360,804...110,383,271
Ensembl chr 8:110,360,804...110,383,271

Snf8

SNF8 subunit of ESCRT-II

involved_in

PMID:21873635

GO_Central

NCBI chr10:80,984,337...80,996,724
Ensembl chr10:80,984,363...80,996,734

Stam

signal transducing adaptor molecule

involved_in

PMID:21873635

GO_Central

NCBI chr17:77,120,235...77,166,173
Ensembl chr17:77,120,158...77,166,467

Vps25

vacuolar protein sorting 25 homolog

involved_in

PMID:21873635

GO_Central

NCBI chr10:86,196,062...86,201,606
Ensembl chr10:86,188,812...86,231,829

Vps28

VPS28 subunit of ESCRT-I

involved_in

PMID:21873635
GO_REF:0000104

GO_REF:0000104, RGD:13792537

NCBI chr 7:108,341,989...108,345,837
Ensembl chr 7:108,341,989...108,345,837

Vps36

vacuolar protein sorting 36 homolog

involved_in

IEA
IBA

GO_REF:0000104
PMID:21873635

GO_REF:0000104, RGD:13792537

NCBI chr16:69,810,404...69,834,789
Ensembl chr16:69,808,193...69,834,810

regulation of ER-associated ubiquitin-dependent protein catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Herpud1

homocysteine inducible ER protein with ubiquitin like domain 1

involved_in

(MGI:5613477|PMID:15147274)
PMID:21873635

PMID:15147274 PMID:21873635

MGI:5613477, RGD:13792537

NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424

regulation of proteasomal ubiquitin-dependent protein catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Araf

A-Raf proto-oncogene, serine/threonine kinase

involved_in

(PMID:22609986)
GO_REF:0000024

PMID:22609986

GO_REF:0000024

NCBI chr X:1,227,392...1,292,356
Ensembl chr X:1,227,392...1,239,073

Commd1

copper metabolism domain containing 1

involved_in

(PMID:17183367)
PMID:21873635

PMID:17183367 PMID:21873635

NCBI chr14:96,880,463...96,984,494
Ensembl chr14:96,880,463...96,984,501

Desi1

desumoylating isopeptidase 1

involved_in

(PMID:29666234)

PMID:29666234

NCBI chr 7:113,519,974...113,542,834
Ensembl chr 7:113,519,980...113,542,845

Foxf2

forkhead box F2

involved_in

(PMID:29374064)

PMID:29374064

NCBI chr17:32,835,730...32,842,555
Ensembl chr17:32,836,777...32,842,176

Glmn

glomulin, FKBP associated protein

acts_upstream_of_or_within

(PMID:22405651)

PMID:22405651

NCBI chr14:2,187,144...2,231,295
Ensembl chr14:2,187,642...2,230,420

Gna12

G protein subunit alpha 12

involved_in

(PMID:22609986)
(MGI:5448916|PMID:22609986)
GO_REF:0000024

PMID:22609986

GO_REF:0000024 MGI:5448916

NCBI chr12:13,805,580...13,886,255
Ensembl chr12:13,805,698...13,886,255

Rad23a

RAD23 homolog A, nucleotide excision repair protein

involved_in

(PMID:12643283)

PMID:12643283

NCBI chr19:23,313,563...23,320,702
Ensembl chr19:23,314,797...23,320,695

Rad23b

RAD23 homolog B, nucleotide excision repair protein

involved_in

(PMID:19435460)

PMID:19435460

NCBI chr 5:70,090,232...70,128,340
Ensembl chr 5:70,090,232...70,128,319

Ube2k

ubiquitin-conjugating enzyme E2K

acts_upstream_of_or_within

(MGI:3806928|PMID:18710920)

PMID:18710920

MGI:3806928

NCBI chr14:42,658,016...42,718,899
Ensembl chr14:42,658,016...42,718,630

Ubqln4

ubiquilin 4

involved_in

(PMID:15280365), (PMID:27113755)

PMID:15280365 PMID:27113755

NCBI chr 2:174,012,726...174,028,062
Ensembl chr 2:174,012,777...174,028,059

Ufl1

Ufm1-specific ligase 1

involved_in
acts_upstream_of_or_within

PMID:21873635
(PMID:20228063)

PMID:20228063 PMID:21873635

NCBI chr 5:38,962,721...38,995,134
Ensembl chr 5:38,962,171...38,995,199

Wnt10b

Wnt family member 10B

acts_upstream_of_or_within

MGI:3582610 (MGI:3820325|PMID:19056892)

PMID:19056892

MGI:3820325

NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892

Xpo1

exportin 1

involved_in

(PMID:29666234)

PMID:29666234

NCBI chr14:97,233,263...97,275,536
Ensembl chr14:97,233,270...97,275,498

regulation of ubiquitin-dependent protein catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

L3mbtl3

L3MBTL histone methyl-lysine binding protein 3

involved_in

(MGI:7387162|PMID:30442713)

PMID:30442713

MGI:7387162

NCBI chr 1:18,988,763...19,089,247
Ensembl chr 1:18,990,618...19,089,263

Lats1

large tumor suppressor kinase 1

involved_in

(PMID:28068668)

PMID:28068668

NCBI chr 1:2,160,411...2,193,640
Ensembl chr 1:2,160,411...2,193,640

Nub1

negative regulator of ubiquitin-like proteins 1

involved_in

PMID:21873635

GO_Central

NCBI chr 4:10,442,917...10,473,689
Ensembl chr 4:10,442,917...10,473,694

Ptk2b

protein tyrosine kinase 2 beta

involved_in

(PMID:19880522)

PMID:19880522

NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282

Tmem168

transmembrane protein 168

acts_upstream_of_or_within
involved_in

(MGI:6511555|PMID:32175648)
GO_REF:0000107

PMID:32175648

GO_REF:0000107 MGI:6511555

NCBI chr 4:41,830,623...41,858,763
Ensembl chr 4:41,830,624...41,858,776

Ube3a

ubiquitin protein ligase E3A

involved_in

(PMID:24728990)
PMID:21873635

PMID:24728990 PMID:21873635

NCBI chr 1:110,070,260...110,161,675
Ensembl chr 1:110,070,480...110,157,250

ribosome-associated ubiquitin-dependent protein catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AABR07064719.2

involved_in

PMID:21873635

GO_Central

Ascc2

activating signal cointegrator 1 complex subunit 2

involved_in

(PMID:32099016)

NCBI chr14:79,503,449...79,547,801
Ensembl chr14:79,503,517...79,545,494

Ascc3

activating signal cointegrator 1 complex subunit 3

involved_in

(PMID:32099016)
GO_REF:0000024

GO_REF:0000024

NCBI chr20:53,510,137...53,795,446
Ensembl chr20:53,510,184...53,790,165

Ltn1

listerin E3 ubiquitin protein ligase 1

involved_in

(PMID:25578875)
PMID:21873635

PMID:25578875 PMID:21873635

NCBI chr11:26,603,903...26,660,871
Ensembl chr11:26,603,903...26,660,886

Nemf

nuclear export mediator factor

involved_in

PMID:21873635
(MGI:6719942|PMID:33406423)
(PMID:25578875), (PMID:33406423), (PMID:33909987)

PMID:25578875 PMID:33406423 PMID:33909987 PMID:21873635

MGI:6719942, RGD:13792537

NCBI chr 6:87,791,650...87,835,826
Ensembl chr 6:87,791,656...87,835,841

Rnf10

ring finger protein 10

involved_in

ISO
ISS
IEA

(PMID:34348161), (PMID:34469731)
GO_REF:0000024
GO_REF:0000107

RGD
UniProt
Ensembl

PMID:34348161 PMID:34469731

GO_REF:0000024 GO_REF:0000107

NCBI chr12:41,341,717...41,375,505
Ensembl chr12:41,341,717...41,375,504

Trip4

thyroid hormone receptor interactor 4

involved_in

(PMID:32099016)

NCBI chr 8:66,351,861...66,439,679
Ensembl chr 8:66,353,248...66,439,774

Zfp598

zinc finger protein 598

involved_in

(PMID:32099016)

NCBI chr10:13,694,224...13,706,235
Ensembl chr10:13,694,286...13,706,233

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Amn1

antagonist of mitotic exit network 1 homolog

involved_in

PMID:21873635

GO_Central

NCBI chr 4:182,155,140...182,182,085
Ensembl chr 4:182,155,142...182,182,016

Btrc

beta-transducin repeat containing E3 ubiquitin protein ligase

involved_in
acts_upstream_of_or_within

(MGI:5299399|PMID:21911472)
(MGI:6509513|PMID:32558204)

PMID:21911472 PMID:32558204

MGI:5299399 MGI:6509513

NCBI chr 1:244,210,299...244,380,126
Ensembl chr 1:244,210,314...244,376,721

Ccnf

cyclin F

involved_in

GO_REF:0000024
(PMID:20596027), (PMID:25557911)

PMID:20596027 PMID:25557911

GO_REF:0000024

NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101

Cul1

cullin 1

involved_in

(MGI:4821082|PMID:12140560)
(PMID:11961546), (PMID:15103331)
PMID:21873635

PMID:11961546 PMID:12140560 PMID:15103331 PMID:21873635

MGI:4821082, RGD:13792537

NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980

Cul2

cullin 2

involved_in

PMID:21873635

GO_Central

NCBI chr17:54,169,086...54,210,197
Ensembl chr17:54,169,086...54,209,968

Cul5

cullin 5

involved_in

PMID:21873635

GO_Central

NCBI chr 8:54,012,963...54,066,751
Ensembl chr 8:54,016,006...54,066,666

Dmac2

distal membrane arm assembly component 2

involved_in

PMID:21873635

GO_Central

NCBI chr 1:81,128,760...81,134,810
Ensembl chr 1:81,128,857...81,134,812

Fbxl12

F-box and leucine-rich repeat protein 12

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr 8:19,175,864...19,183,373
Ensembl chr 8:19,160,352...19,183,607

Fbxl15

F-box and leucine-rich repeat protein 15

involved_in

(PMID:21572392)
PMID:21873635
GO_REF:0000024

PMID:21572392 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr 1:245,189,732...245,191,973
Ensembl chr 1:245,189,736...245,192,007

Fbxl16

F-box and leucine-rich repeat protein 16

involved_in

PMID:21873635

GO_Central

NCBI chr10:14,829,453...14,841,739
Ensembl chr10:14,829,449...14,840,986

Fbxl17

F-box and leucine-rich repeat protein 17

involved_in

(PMID:24035498), (PMID:27234298)

PMID:24035498 PMID:27234298

NCBI chr 9:102,780,573...103,206,755
Ensembl chr 9:102,782,440...103,208,950

Fbxl18

F-box and leucine-rich repeat protein 18

involved_in

PMID:21873635

GO_Central

NCBI chr12:11,674,538...11,701,317
Ensembl chr12:11,676,115...11,699,181

Fbxl2

F-box and leucine-rich repeat protein 2

involved_in

(PMID:23604317), (PMID:26037928)
PMID:21873635
(MGI:5488521|PMID:23542741)

PMID:23542741 PMID:23604317 PMID:26037928 PMID:21873635

MGI:5488521, RGD:13792537

NCBI chr 8:113,916,660...113,965,137
Ensembl chr 8:113,913,373...113,965,066

Fbxl21

F-box and leucine-rich repeat protein 21

involved_in

PMID:21873635

GO_Central

NCBI chr17:8,060,412...8,077,415
Ensembl chr17:8,060,414...8,073,359

Fbxl22

F-box and leucine-rich repeat protein 22

involved_in

PMID:21873635

GO_Central

NCBI chr 8:67,069,998...67,076,685
Ensembl chr 8:67,069,998...67,076,685

Fbxl3

F-box and leucine-rich repeat protein 3

involved_in

PMID:21873635
(MGI:5470183|PMID:23452855), (MGI:5487698|PMID:23452856)
(PMID:17463251)

PMID:17463251 PMID:23452855 PMID:23452856 PMID:21873635

MGI:5470183 MGI:5487698, RGD:13792537

NCBI chr15:79,906,795...79,926,678
Ensembl chr15:79,906,795...79,927,867

Fbxl4

F-box and leucine-rich repeat protein 4

involved_in

PMID:21873635

GO_Central

NCBI chr 5:35,955,801...36,029,446
Ensembl chr 5:35,955,812...36,029,443

Fbxl5

F-box and leucine-rich repeat protein 5

involved_in

(PMID:17532294), (PMID:19762596), (PMID:19762597)
PMID:21873635

PMID:17532294 PMID:19762596 PMID:19762597 PMID:21873635

NCBI chr14:67,305,109...67,347,383
Ensembl chr14:67,267,801...67,347,383

Fbxl6

F-box and leucine-rich repeat protein 6

involved_in

PMID:21873635

GO_Central

NCBI chr 7:108,259,097...108,262,528
Ensembl chr 7:108,257,160...108,262,513

Fbxl7

F-box and leucine-rich repeat protein 7

involved_in

(PMID:25778398), (PMID:28218735)
PMID:21873635
(MGI:5426128|PMID:22306998), (MGI:6368091|PMID:25778398)

PMID:22306998 PMID:25778398 PMID:28218735 PMID:21873635

MGI:5426128 MGI:6368091, RGD:13792537

NCBI chr 2:77,139,775...77,509,223
Ensembl chr 2:77,140,826...77,509,223

Fbxl8

F-box and leucine-rich repeat protein 8

involved_in

PMID:21873635

GO_Central

NCBI chr19:33,142,653...33,147,268
Ensembl chr19:33,142,715...33,147,262

Fbxo17

F-box protein 17

involved_in

PMID:21873635

GO_Central

NCBI chr 1:84,002,276...84,024,455
Ensembl chr 1:84,002,267...84,024,453

Fbxo2

F-box protein 2

involved_in

PMID:21873635
(MGI:4821082|PMID:12140560)

PMID:12140560 PMID:21873635

MGI:4821082, RGD:13792537

NCBI chr 5:158,592,926...158,598,355
Ensembl chr 5:158,592,925...158,598,355

Fbxo27

F-box protein 27

involved_in

PMID:21873635

GO_Central

NCBI chr 1:83,965,426...83,987,781
Ensembl chr 1:83,965,986...83,987,778

Fbxo3

F-box protein 3

involved_in

GO_REF:0000024
(MGI:5488521|PMID:23542741)
(PMID:26037928)

PMID:23542741 PMID:26037928

GO_REF:0000024 MGI:5488521

NCBI chr 3:90,417,262...90,449,557
Ensembl chr 3:90,417,297...90,449,557

Fbxo31

F-box protein 31

involved_in

GO_REF:0000024
PMID:21873635
(PMID:19412162)

PMID:19412162 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr19:49,624,818...49,656,083
Ensembl chr19:49,627,686...49,656,010

Fbxo33

F-box protein 33

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr 6:76,900,619...76,934,232
Ensembl chr 6:76,900,631...76,932,669

Fbxo38

F-box protein 38

involved_in

(PMID:30487606)
PMID:21873635

PMID:30487606 PMID:21873635

NCBI chr18:55,956,950...56,004,013
Ensembl chr18:55,956,959...56,003,961

Fbxo39

F-box protein 39

involved_in

PMID:21873635

GO_Central

NCBI chr10:56,929,699...56,934,911
Ensembl chr10:56,932,297...56,934,906

Fbxo4

F-box protein 4

involved_in

PMID:21873635
(PMID:20159592), (PMID:29142209)

PMID:20159592 PMID:29142209 PMID:21873635

NCBI chr 2:53,174,798...53,187,792
Ensembl chr 2:53,174,798...53,187,792

Fbxo44

F-box protein 44

involved_in

PMID:21873635

GO_Central

NCBI chr 5:158,583,363...158,592,510
Ensembl chr 5:158,583,366...158,592,363

Fbxo48

F-box protein 48

involved_in

GO_REF:0000104

GO_REF:0000104

NCBI chr14:91,380,857...91,382,314
Ensembl chr14:91,380,857...91,382,314

Fbxo6

F-box protein 6

involved_in

IBA
ISO
ISS

PMID:21873635
(MGI:2679753|PMID:12939278)
GO_REF:0000024
(PMID:19716789)

PMID:12939278 PMID:19716789 PMID:21873635

GO_REF:0000024 MGI:2679753, RGD:13792537

NCBI chr 5:158,576,729...158,582,520
Ensembl chr 5:158,576,759...158,582,525

Fbxo9

f-box protein 9

involved_in

ISO
IBA
IEA
ISS

(PMID:23263282)
PMID:21873635
GO_REF:0000104
GO_REF:0000024

PMID:23263282 PMID:21873635

GO_REF:0000024 GO_REF:0000104, RGD:13792537

NCBI chr 8:78,958,482...78,984,015
Ensembl chr 8:78,958,483...78,983,949

Fbxw11

F-box and WD repeat domain containing 11

involved_in

(PMID:20347421)
(MGI:2176150|PMID:11896578)

PMID:11896578 PMID:20347421

MGI:2176150

NCBI chr10:17,232,735...17,330,584
Ensembl chr10:17,227,181...17,330,571

Fbxw4

F-box and WD repeat domain containing 4

involved_in

PMID:21873635

GO_Central

NCBI chr 1:244,426,892...244,514,188
Ensembl chr 1:244,426,896...244,514,163

Fbxw5

F-box and WD repeat domain containing 5

involved_in

GO_REF:0000024
(MGI:5476881|PMID:23314863)
(PMID:21725316)

PMID:21725316 PMID:23314863

GO_REF:0000024 MGI:5476881

NCBI chr 3:8,322,543...8,327,092
Ensembl chr 3:8,322,543...8,327,092

Fbxw7

F-box and WD repeat domain containing 7

involved_in

PMID:21953459
(MGI:6107392|PMID:21953459)
(PMID:28007894)
(PMID:15103331), (PMID:17434132)

PMID:15103331 PMID:17434132 PMID:21953459 PMID:28007894 PMID:21953459

MGI:6107392, RGD:13464262

NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941

Kif14

kinesin family member 14

involved_in

(PMID:24854087)

PMID:24854087

NCBI chr13:47,926,975...47,990,598
Ensembl chr13:47,927,044...47,989,164

Lrrc29

leucine rich repeat containing 29

involved_in

PMID:21873635

GO_Central

NCBI chr19:33,181,713...33,203,583
Ensembl chr19:33,188,352...33,203,545

Nccrp1

NCCRP1, F-box associated domain containing

involved_in

PMID:21873635

GO_Central

NCBI chr 1:83,835,083...83,838,620
Ensembl chr 1:83,835,083...83,838,676

Rbx1

ring-box 1

involved_in

(PMID:15103331)
(MGI:4821082|PMID:12140560)

PMID:12140560 PMID:15103331

MGI:4821082

NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051

RGD1565987

similar to F-box and leucine-rich repeat protein 18

involved_in

GO_REF:0000002

PMID:12140560 PMID:15103331 PMID:20347421 PMID:21873635

GO_REF:0000002

NCBI chr 5:95,460,480...95,464,873
Ensembl chr 5:95,462,188...95,465,129

Skp1

S-phase kinase-associated protein 1

involved_in

ISS
ISO
IEA
IBA

GO_REF:0000024
(MGI:4821082|PMID:12140560)
GO_REF:0000107
PMID:21873635
(PMID:15103331), (PMID:20347421)

UniProt
RGD
Ensembl

GO_REF:0000024 GO_REF:0000107 MGI:4821082, RGD:13792537

NCBI chr10:36,401,987...36,417,066
Ensembl chr10:36,402,153...36,417,388

Skp2

S-phase kinase associated protein 2

involved_in

PMID:21873635

GO_Central

NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338

Tmem249

transmembrane protein 249

involved_in

PMID:21873635

GO_Central

NCBI chr 7:108,256,535...108,259,429
Ensembl chr 7:108,257,160...108,262,513

Wwtr1

WW domain containing transcription regulator 1

acts_upstream_of_or_within

MGI:3759999 (MGI:3758168|PMID:17636028)

PMID:17636028

MGI:3758168

NCBI chr 2:141,651,159...141,766,919
Ensembl chr 2:141,648,108...141,766,968

transcription factor catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Taf1

TATA-box binding protein associated factor 1

involved_in

(PMID:20181722)

PMID:20181722

NCBI chr X:66,640,915...66,716,543
Ensembl chr X:66,640,982...66,716,543

ubiquitin-dependent ERAD pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Amfr

autocrine motility factor receptor

involved_in

(PMID:11724934), (PMID:16168377), (PMID:17872946)

PMID:11724934 PMID:16168377 PMID:17872946

NCBI chr19:10,996,705...11,032,260
Ensembl chr19:10,996,099...11,032,247

Ankzf1

ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1

involved_in

PMID:21873635

GO_Central

NCBI chr 9:76,688,223...76,695,141
Ensembl chr 9:76,688,194...76,696,469

Aup1

AUP1, lipid droplet regulating VLDL assembly factor

involved_in

(PMID:23223569)
PMID:21873635
GO_REF:0000024

PMID:23223569 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr 4:115,560,274...115,563,346
Ensembl chr 4:115,560,261...115,563,346

BAG cochaperone 6

involved_in

IBA
IEA
ISS
ISO

PMID:21873635
GO_REF:0000107
GO_REF:0000024
(PMID:23129660), (PMID:24981174), (PMID:26565908)

PMID:23129660 PMID:24981174 PMID:26565908 PMID:21873635

GO_REF:0000024 GO_REF:0000107, RGD:13792537

NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657

Calr

calreticulin

involved_in

PMID:21873635

GO_Central

NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414

Calr3

calreticulin 3

involved_in

PMID:21873635

GO_Central

NCBI chr16:17,396,064...17,423,166
Ensembl chr16:17,396,247...17,423,015

Calr4

calreticulin 4

involved_in

PMID:21873635

GO_Central

NCBI chr 5:123,986,870...124,022,436
Ensembl chr 5:123,987,474...124,022,417

Canx

calnexin

involved_in

PMID:21873635

GO_Central

NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821

Ccdc47

coiled-coil domain containing 47

acts_upstream_of_or_within

MGI:3722141 (MGI:5605216|PMID:25009997)

PMID:25009997

MGI:5605216

NCBI chr10:91,130,303...91,148,829
Ensembl chr10:91,130,303...91,148,881

Clgn

calmegin

involved_in

PMID:21873635

GO_Central

NCBI chr19:24,695,140...24,728,542
Ensembl chr19:24,696,875...24,728,758

Derl1

derlin 1

involved_in

(PMID:15215856), (PMID:17872946), (PMID:18555783)
PMID:21873635

PMID:15215856 PMID:17872946 PMID:18555783 PMID:21873635

NCBI chr 7:89,404,413...89,427,095
Ensembl chr 7:89,404,417...89,427,145

Derl2

derlin 2

involved_in

(PMID:16449189)
PMID:21873635

PMID:16449189 PMID:21873635

NCBI chr10:55,727,764...55,739,462
Ensembl chr10:55,727,643...55,739,518

Derl3

derlin 3

involved_in

(PMID:22607976)
PMID:21873635

PMID:22607976 PMID:21873635

NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027

Dnajb2

DnaJ heat shock protein family (Hsp40) member B2

involved_in

(PMID:15936278)
PMID:21873635

PMID:15936278 PMID:21873635

NCBI chr 9:76,731,060...76,739,278
Ensembl chr 9:76,731,065...76,739,277

Dnajb9

DnaJ heat shock protein family (Hsp40) member B9

involved_in

GO_REF:0000024
PMID:21873635
(MGI:5499714|PMID:22267725)
(PMID:18400946)

PMID:18400946 PMID:22267725 PMID:21873635

GO_REF:0000024 MGI:5499714, RGD:13792537

NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063

Dnajc10

DnaJ heat shock protein family (Hsp40) member C10

involved_in

ISO
IEA
ISS

(PMID:18400946)
GO_REF:0000104
(MGI:4943381|PMID:18653895), (MGI:4947480|PMID:21329881)
GO_REF:0000024

PMID:18400946 PMID:18653895 PMID:21329881

GO_REF:0000024 GO_REF:0000104 MGI:4943381 MGI:4947480

NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719

Ecpas

Ecm29 proteasome adaptor and scaffold

involved_in

(PMID:15496406)
PMID:21873635

PMID:15496406 PMID:21873635

NCBI chr 5:73,601,745...73,714,026
Ensembl chr 5:73,604,533...73,713,860

Edem1

ER degradation enhancing alpha-mannosidase like protein 1

acts_upstream_of_or_within

(MGI:2178766|PMID:11375934)

PMID:11375934

MGI:2178766

NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717

Eif2ak3

eukaryotic translation initiation factor 2 alpha kinase 3

involved_in

(MGI:6467680|PMID:17707796)

PMID:17707796

MGI:6467680

NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911

Erlec1

endoplasmic reticulum lectin 1

involved_in

(PMID:18502753)
PMID:21873635

PMID:18502753 PMID:21873635

NCBI chr14:104,655,745...104,693,508
Ensembl chr14:104,655,673...104,693,480

Erlin1

ER lipid raft associated 1

involved_in

(PMID:19240031)

PMID:19240031

NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394

Erlin2

ER lipid raft associated 2

involved_in

(PMID:19240031)

PMID:19240031

NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671

Faf1

Fas associated factor 1

involved_in

PMID:21873635

GO_Central

PMID:24215460 PMID:21873635

NCBI chr 5:124,426,032...124,790,014
Ensembl chr 5:124,426,062...124,789,977

Faf2

Fas associated factor family member 2

involved_in

ISO
IBA
ISS
IEA

(PMID:24215460)
PMID:21873635
GO_REF:0000024
GO_REF:0000107

RGD
UniProt
Ensembl

GO_REF:0000024 GO_REF:0000107, RGD:13792537

NCBI chr17:9,947,216...9,989,474
Ensembl chr17:9,947,220...9,989,485

Fbxo17

F-box protein 17

involved_in

PMID:21873635

GO_Central

NCBI chr 1:84,002,276...84,024,455
Ensembl chr 1:84,002,267...84,024,453

Fbxo2

F-box protein 2

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:3573989|PMID:15723043)

PMID:15723043 PMID:21873635

MGI:3573989, RGD:13792537

NCBI chr 5:158,592,926...158,598,355
Ensembl chr 5:158,592,925...158,598,355

Fbxo27

F-box protein 27

involved_in

PMID:21873635

GO_Central

NCBI chr 1:83,965,426...83,987,781
Ensembl chr 1:83,965,986...83,987,778

Fbxo44

F-box protein 44

involved_in

PMID:21873635

GO_Central

NCBI chr 5:158,583,363...158,592,510
Ensembl chr 5:158,583,366...158,592,363

Fbxo6

F-box protein 6

involved_in

ISS
ISO
IBA

GO_REF:0000024
(MGI:2679753|PMID:12939278)
PMID:21873635

PMID:12939278 PMID:21873635

GO_REF:0000024 MGI:2679753, RGD:13792537

NCBI chr 5:158,576,729...158,582,520
Ensembl chr 5:158,576,759...158,582,525

Foxred2

FAD-dependent oxidoreductase domain containing 2

involved_in

(PMID:19706418)
PMID:21873635

PMID:19706418 PMID:21873635

NCBI chr 7:109,521,761...109,538,300
Ensembl chr 7:109,521,761...109,540,874

Herpud1

homocysteine inducible ER protein with ubiquitin like domain 1

involved_in

(PMID:28827405)

PMID:18264092 PMID:21873635

PMID:28827405

NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424

Hsp90b1

heat shock protein 90 beta family member 1

involved_in

ISS
IEA
IBA
ISO

GO_REF:0000024
GO_REF:0000107
PMID:21873635
(PMID:18264092)

UniProt
Ensembl
RGD

GO_REF:0000024 GO_REF:0000107, RGD:13792537

NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788

Hspa5

heat shock protein family A (Hsp70) member 5

involved_in

PMID:21873635

GO_Central

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

Jkamp

JNK1/MAPK8-associated membrane protein

involved_in

(PMID:19269966)
PMID:21873635

PMID:19269966 PMID:21873635

NCBI chr 6:90,648,043...90,661,985
Ensembl chr 6:90,648,160...90,662,501

Jkampl

JNK1/MAPK8 associated membrane protein like

involved_in

PMID:21873635

GO_Central

NCBI chr 4:105,520,442...105,521,542
Ensembl chr 4:105,520,442...105,521,542

Man1a1

mannosidase, alpha, class 1A, member 1

involved_in

(PMID:27108681)

PMID:27108681

NCBI chr20:33,202,509...33,385,747
Ensembl chr20:33,202,517...33,385,824

Man1b1

mannosidase, alpha, class 1B, member 1

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:3054306|PMID:15294975)
(PMID:18003979)

PMID:15294975 PMID:18003979 PMID:21873635

MGI:3054306, RGD:13792537

NCBI chr 3:8,143,877...8,165,007
Ensembl chr 3:8,143,381...8,165,006

Marchf6

membrane associated ring-CH-type finger 6

involved_in

PMID:21873635

GO_Central

NCBI chr 2:82,455,686...82,532,917
Ensembl chr 2:82,455,689...82,532,910

Nccrp1

NCCRP1, F-box associated domain containing

involved_in

PMID:21873635

GO_Central

NCBI chr 1:83,835,083...83,838,620
Ensembl chr 1:83,835,083...83,838,676

Nploc4

NPL4 homolog, ubiquitin recognition factor

involved_in

EXP
ISO

PMID:12847084
(MGI:5634892|PMID:12847084)

PMID:12847084 PMID:12847084

MGI:5634892, RGD:10047330

NCBI chr10:105,654,395...105,709,958
Ensembl chr10:105,654,812...105,709,913

Os9

OS9, endoplasmic reticulum lectin

involved_in

ISS
IEA
IBA
ISO

GO_REF:0000024
GO_REF:0000104
PMID:21873635
(PMID:18264092), (PMID:18417469), (PMID:19346256)

PMID:18264092 PMID:18417469 PMID:19346256 PMID:21873635

GO_REF:0000024 GO_REF:0000104, RGD:13792537

NCBI chr 7:62,915,498...62,957,591
Ensembl chr 7:62,915,515...62,943,745

Psmc6

proteasome 26S subunit, ATPase 6

involved_in

PMID:21873635

GO_Central

NCBI chr15:18,542,585...18,564,057
Ensembl chr15:18,542,563...18,564,055

Rnf103

ring finger protein 103

involved_in

IEA
IBA
ISO

GO_REF:0000107
PMID:21873635
(PMID:18675248)

PMID:18675248 PMID:21873635

GO_REF:0000107, RGD:13792537

NCBI chr 4:103,526,456...103,542,529
Ensembl chr 4:103,526,502...103,555,919

Rnf121

ring finger protein 121

involved_in

PMID:21873635

GO_Central

NCBI chr 1:156,377,583...156,439,923
Ensembl chr 1:156,377,364...156,446,826

Rnf185

ring finger protein 185

involved_in

(PMID:24019521)

PMID:24019521

NCBI chr14:78,292,517...78,329,832
Ensembl chr14:78,292,516...78,329,864

Rnf5

ring finger protein 5

involved_in

UniProtKB:Q96GF1 (PMID:24019521)

PMID:24019521

NCBI chr20:4,145,539...4,147,985
Ensembl chr20:4,145,507...4,147,985

Sec61b

SEC61 translocon subunit beta

involved_in

(PMID:8945469)

PMID:8945469

NCBI chr 5:61,773,594...61,781,804
Ensembl chr 5:61,773,594...61,781,804

Selenos

selenoprotein S

involved_in

IBA
IEA
ISO

PMID:21873635
GO_REF:0000107
(PMID:15215856)

PMID:15215856 PMID:21873635

GO_REF:0000107, RGD:13792537

NCBI chr 1:119,659,779...119,669,546
Ensembl chr 1:119,659,751...119,669,833

small glutamine rich tetratricopeptide repeat co-chaperone alpha

involved_in

(PMID:23129660)
GO_REF:0000024

PMID:23129660

GO_REF:0000024

NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458

Stt3b

STT3 oligosaccharyltransferase complex catalytic subunit B

involved_in

(PMID:22607976)

PMID:22607976

NCBI chr 8:114,928,678...114,994,027
Ensembl chr 8:114,917,824...114,994,028

Stub1

STIP1 homology and U-box containing protein 1

involved_in

(PMID:23990462)

PMID:23990462

NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046

Syvn1

synoviolin 1

involved_in
acts_upstream_of_or_within

(PMID:12459480), (PMID:14593114), (PMID:17059562), (PMID:22607976), (PMID:28827405)
(PMID:21245296)

PMID:12459480 PMID:14593114 PMID:17059562 PMID:21245296 PMID:22607976 More...

NCBI chr 1:203,339,235...203,346,137
Ensembl chr 1:203,339,619...203,346,152

Tmem129

transmembrane protein 129, E3 ubiquitin ligase

involved_in

(PMID:24807418)

PMID:24807418

NCBI chr14:77,065,391...77,070,871
Ensembl chr14:77,065,841...77,070,865

Tmem67

transmembrane protein 67

involved_in

(PMID:19815549)
GO_REF:0000107

PMID:21343306 PMID:21873635

PMID:19815549

GO_REF:0000107

NCBI chr 5:25,536,458...25,589,378
Ensembl chr 5:25,536,458...25,589,334

Tmub1

transmembrane and ubiquitin-like domain containing 1

involved_in

ISO
IEA
IBA

(PMID:21343306)
GO_REF:0000002
PMID:21873635

RGD
InterPro

GO_REF:0000002, RGD:13792537

NCBI chr 4:10,729,494...10,732,060
Ensembl chr 4:10,729,250...10,732,060

Tmub2

transmembrane and ubiquitin-like domain containing 2

involved_in

PMID:21873635
GO_REF:0000002

GO_REF:0000002, RGD:13792537

NCBI chr10:87,238,543...87,242,968
Ensembl chr10:87,238,548...87,242,779

Trim13

tripartite motif-containing 13

involved_in

PMID:21873635
(PMID:17314412)

PMID:17314412 PMID:21873635

NCBI chr15:35,733,548...35,772,676
Ensembl chr15:35,734,107...35,772,677

Trim25

tripartite motif-containing 25

involved_in

(PMID:24810856)

PMID:24810856

NCBI chr10:73,812,818...73,831,271
Ensembl chr10:73,812,818...73,831,257

Ube2g2

ubiquitin-conjugating enzyme E2G 2

involved_in
acts_upstream_of_or_within

(PMID:22607976)
(MGI:2154298|PMID:11278356)
PMID:21873635

PMID:11278356 PMID:22607976 PMID:21873635

MGI:2154298, RGD:13792537

NCBI chr20:10,983,734...11,005,468
Ensembl chr20:10,983,742...11,005,447

Ube2j1

ubiquitin-conjugating enzyme E2, J1

involved_in
acts_upstream_of_or_within

PMID:21873635
(PMID:21245296)
(PMID:22607976)
(MGI:5532755|PMID:24020373)

PMID:21245296 PMID:22607976 PMID:24020373 PMID:21873635

MGI:5532755, RGD:13792537

NCBI chr 5:47,422,513...47,441,476
Ensembl chr 5:47,422,587...47,441,461

Ube2j2

ubiquitin-conjugating enzyme E2, J2

involved_in

PMID:21873635
(PMID:24807418)

PMID:24807418 PMID:21873635

NCBI chr 5:166,533,374...166,547,811
Ensembl chr 5:166,533,418...166,547,804

Ube4a

ubiquitination factor E4A

involved_in

PMID:21873635
GO_REF:0000002

GO_REF:0000002, RGD:13792537

NCBI chr 8:45,236,022...45,278,129
Ensembl chr 8:45,236,026...45,278,038

Ube4b

ubiquitination factor E4B

involved_in

PMID:21873635

GO_Central

NCBI chr 5:159,766,829...159,870,509
Ensembl chr 5:159,766,829...159,870,509

Ubqln1

ubiquilin 1

involved_in

IEA
IBA
ISS
ISO

GO_REF:0000107
PMID:21873635
GO_REF:0000024
(PMID:19822669)

PMID:19822669 PMID:21873635

GO_REF:0000024 GO_REF:0000107, RGD:13792537

NCBI chr17:6,439,002...6,477,096
Ensembl chr17:6,439,002...6,477,090

Ubqln2

ubiquilin 2

involved_in

PMID:21873635
(PMID:24215460)

PMID:24215460 PMID:21873635

NCBI chr X:17,853,086...17,856,505
Ensembl chr X:17,853,114...17,856,505

Ubxn10

UBX domain protein 10

involved_in

PMID:21873635

GO_Central

NCBI chr 5:150,953,772...150,959,608
Ensembl chr 5:150,950,731...150,959,744

Ubxn4

UBX domain protein 4

involved_in

(PMID:19822669)
PMID:21873635
GO_REF:0000024

PMID:19822669 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr13:39,740,077...39,772,347
Ensembl chr13:39,740,107...39,772,491

Ubxn8

UBX domain protein 8

involved_in

(PMID:21949850)
PMID:21873635

PMID:21949850 PMID:21873635

NCBI chr16:58,536,086...58,557,684
Ensembl chr16:58,536,086...58,557,684

Ufd1

ubiquitin recognition factor in ER associated degradation 1

involved_in

EXP
IBA
ISO

PMID:12847084
PMID:21873635
(MGI:5634892|PMID:12847084)

PMID:12847084 PMID:12847084 PMID:21873635

MGI:5634892, RGD:10047330, RGD:13792537

NCBI chr11:82,161,618...82,185,107
Ensembl chr11:82,161,619...82,185,087

Umod

uromodulin

acts_upstream_of_or_within

(MGI:5916257|PMID:28437467)

PMID:19465887 PMID:21873635

PMID:28437467

MGI:5916257

NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302

Usp19

ubiquitin specific peptidase 19

involved_in

ISS
IBA
IEA
ISO

GO_REF:0000024
PMID:21873635
GO_REF:0000107
(PMID:19465887)

UniProt
Ensembl
RGD

GO_REF:0000024 GO_REF:0000107, RGD:13792537

NCBI chr 8:109,190,727...109,201,761
Ensembl chr 8:109,190,724...109,201,741

valosin-containing protein

involved_in

ISO
IBA
EXP
ISS

(PMID:17872946), (PMID:22607976)
PMID:21873635
(MGI:5634892|PMID:12847084)
GO_REF:0000024

PMID:12847084 PMID:17872946 PMID:22607976 PMID:21873635 PMID:12847084

GO_REF:0000024 MGI:5634892, RGD:13792537, RGD:10047330

NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571

Wfs1

wolframin ER transmembrane glycoprotein

involved_in

(PMID:20160352)
(MGI:5009360|PMID:20160352)

PMID:20160352

MGI:5009360

NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602

Yod1

YOD1 deubiquitinase

involved_in

ISO
ISS
IBA

(PMID:19818707)
GO_REF:0000024
PMID:21873635

PMID:19818707 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr13:42,175,313...42,177,030
Ensembl chr13:42,174,820...42,177,205

ubiquitin-dependent glycoprotein ERAD pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Edem1

ER degradation enhancing alpha-mannosidase like protein 1

involved_in

(PMID:21062743), (PMID:25092655)

PMID:21062743 PMID:25092655

NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717

Edem2

ER degradation enhancing alpha-mannosidase like protein 2

involved_in

(PMID:15537790)

PMID:15537790

NCBI chr 3:144,201,604...144,227,423
Ensembl chr 3:144,201,605...144,227,485

ubiquitin-dependent protein catabolic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AABR07044940.1

involved_in

PMID:21873635

GO_Central

Amfr

autocrine motility factor receptor

involved_in

(PMID:16168377), (PMID:17043353)
PMID:21873635

PMID:16168377 PMID:17043353 PMID:21873635

NCBI chr19:10,996,705...11,032,260
Ensembl chr19:10,996,099...11,032,247

Anapc11

anaphase promoting complex subunit 11

involved_in

PMID:21873635

GO_Central

NCBI chr10:105,875,209...105,886,307

Anapc2

anaphase promoting complex subunit 2

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr 3:8,086,434...8,098,182
Ensembl chr 3:8,086,462...8,098,178

Ankib1

ankyrin repeat and IBR domain containing 1

involved_in

PMID:21873635

GO_Central

NCBI chr 4:30,333,678...30,457,781
Ensembl chr 4:30,333,677...30,457,781

Arel1

apoptosis resistant E3 ubiquitin protein ligase 1

involved_in

(PMID:23479728)
(MGI:5498443|PMID:23479728)

PMID:23479728

MGI:5498443

NCBI chr 6:104,560,556...104,617,712
Ensembl chr 6:104,564,986...104,617,628

Arih1

ariadne RBR E3 ubiquitin protein ligase 1

acts_upstream_of_or_within
involved_in

UniProtKB:P68037 (MGI:1340728|PMID:10431818)
PMID:21873635

PMID:10431818 PMID:21873635

MGI:1340728, RGD:13792537

NCBI chr 8:59,777,378...59,879,762
Ensembl chr 8:59,777,379...59,880,245

Arih2

ariadne RBR E3 ubiquitin protein ligase 2

involved_in
acts_upstream_of_or_within

(PMID:16118314)
PMID:21873635
UniProtKB:P68037 (MGI:1340728|PMID:10431818)

PMID:10431818 PMID:16118314 PMID:21873635

MGI:1340728, RGD:13792537

NCBI chr 8:109,296,738...109,355,909
Ensembl chr 8:109,296,738...109,355,852

Arrb1

arrestin, beta 1

involved_in

(PMID:23886940)
(MGI:5916812|PMID:23886940)
GO_REF:0000024

PMID:23886940

GO_REF:0000024 MGI:5916812

NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061

Arrdc1

arrestin domain containing 1

involved_in
NOT|involved_in

(PMID:23886940)
GO_REF:0000024
(PMID:27462458)

PMID:23886940 PMID:27462458

GO_REF:0000024

NCBI chr 3:7,735,002...7,742,195
Ensembl chr 3:7,735,011...7,742,197

Arrdc4

arrestin domain containing 4

NOT|involved_in

(MGI:5804712|PMID:27462458)

PMID:27462458

MGI:5804712

NCBI chr 1:122,369,355...122,383,351
Ensembl chr 1:122,369,360...122,383,290

Asb2

ankyrin repeat and SOCS box-containing 2

acts_upstream_of_or_within
involved_in

(MGI:4830849|PMID:19300455)
PMID:21873635
(MGI:6102779|PMID:26343497)
(PMID:24044920)

PMID:19300455 PMID:24044920 PMID:26343497 PMID:21873635

MGI:4830849 MGI:6102779, RGD:13792537

NCBI chr 6:122,474,754...122,511,014
Ensembl chr 6:122,474,756...122,510,854

Atxn3

ataxin 3

acts_upstream_of_or_within

MGI:3833681 (MGI:3833207|PMID:17764659)

PMID:17764659

MGI:3833207

NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902

BAG cochaperone 6

involved_in

GO_REF:0000024
(PMID:20676083)
(MGI:4887294|PMID:20713601)