Plaa (phospholipase A2 activating protein) - Rat Genome Database

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Gene: Plaa (phospholipase A2 activating protein) Heterocephalus glaber
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Symbol: Plaa
Name: phospholipase A2 activating protein
RGD ID: 18910779
Description: ENCODES a protein that exhibits phospholipase A2 activator activity (ortholog); INVOLVED IN cellular response to lipopolysaccharide (ortholog); inflammatory response (ortholog); macroautophagy (ortholog); ASSOCIATED WITH genetic disease (ortholog); Inflammation (ortholog); Neurodevelopmental Disorder with Progressive Microcephaly, Spasticity, and Brain Anomalies (ortholog); FOUND IN extracellular exosome (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Phospholipase A-2-activating protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473631,127,955 - 31,169,739 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473631,127,955 - 31,169,680 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Plaa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473631,127,955 - 31,169,739 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473631,127,955 - 31,169,680 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PLAA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38926,903,372 - 26,947,242 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl926,903,372 - 26,947,242 (-)EnsemblGRCh38hg38GRCh38
GRCh37926,903,370 - 26,947,240 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36926,894,518 - 26,937,138 (-)NCBINCBI36Build 36hg18NCBI36
Build 34926,894,517 - 26,925,207NCBI
Celera926,831,534 - 26,875,621 (-)NCBICelera
Cytogenetic Map9p21.2NCBI
HuRef926,856,258 - 26,900,343 (-)NCBIHuRef
CHM1_1926,903,156 - 26,947,247 (-)NCBICHM1_1
T2T-CHM13v2.0926,913,987 - 26,957,845 (-)NCBIT2T-CHM13v2.0
Plaa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39494,453,371 - 94,491,410 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl494,455,751 - 94,491,481 (-)EnsemblGRCm39 Ensembl
GRCm38494,565,139 - 94,603,247 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl494,567,514 - 94,603,244 (-)EnsemblGRCm38mm10GRCm38
MGSCv37494,231,830 - 94,269,938 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36494,061,188 - 94,095,196 (-)NCBIMGSCv36mm8
Celera492,974,316 - 93,012,476 (-)NCBICelera
Cytogenetic Map4C5NCBI
cM Map443.34NCBI
Plaa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85114,544,327 - 114,576,023 (-)NCBIGRCr8
mRatBN7.25109,428,600 - 109,460,373 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5109,428,265 - 109,460,282 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5112,008,911 - 112,038,934 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05113,734,700 - 113,764,723 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05113,796,931 - 113,826,954 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05113,548,913 - 113,578,928 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5113,548,913 - 113,578,928 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05117,491,921 - 117,523,644 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45114,869,341 - 114,899,356 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15114,874,675 - 114,904,441 (-)NCBI
Celera5108,057,280 - 108,087,304 (-)NCBICelera
Cytogenetic Map5q33NCBI
Plaa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554727,879,196 - 7,919,834 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554727,879,196 - 7,915,040 (+)NCBIChiLan1.0ChiLan1.0
PLAA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21197,594,820 - 97,639,872 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1997,603,602 - 97,645,817 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0926,749,607 - 26,793,580 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1927,357,357 - 27,401,080 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl927,357,437 - 27,401,103 (-)Ensemblpanpan1.1panPan2
PLAA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11145,121,423 - 45,159,093 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1145,121,588 - 45,159,098 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1143,796,828 - 43,834,515 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01146,066,215 - 46,103,907 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1146,066,215 - 46,103,981 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11144,723,113 - 44,761,001 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01144,613,092 - 44,650,799 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01145,359,820 - 45,397,506 (-)NCBIUU_Cfam_GSD_1.0
Plaa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947159,970,040 - 160,003,099 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366112,665,370 - 2,700,538 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366112,665,294 - 2,698,372 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLAA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1196,176,456 - 196,219,834 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11196,176,004 - 196,219,614 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21218,624,039 - 218,668,148 (+)NCBISscrofa10.2Sscrofa10.2susScr3


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000015519   ⟹   ENSHGLP00000015360
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473631,127,955 - 31,169,739 (-)Ensembl
RefSeq Acc Id: XM_004838364   ⟹   XP_004838421
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473631,127,955 - 31,169,508 (-)NCBI
RefSeq Acc Id: XM_004838365   ⟹   XP_004838422
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473631,127,955 - 31,169,680 (-)NCBI
RefSeq Acc Id: XM_021252933   ⟹   XP_021108592
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473631,128,123 - 31,169,481 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004838421 (Get FASTA)   NCBI Sequence Viewer  
  XP_004838422 (Get FASTA)   NCBI Sequence Viewer  
  XP_021108592 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB11328 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000015360
GenBank Protein JAO02097 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004838422   ⟸   XM_004838365
- Peptide Label: isoform X2
- UniProtKB: A0AAX6NWE2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004838421   ⟸   XM_004838364
- Peptide Label: isoform X1
- UniProtKB: G5BPW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021108592   ⟸   XM_021252933
- Peptide Label: isoform X3
- UniProtKB: A0AAX6SKN0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000015360   ⟸   ENSHGLT00000015519


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000010977 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000015519 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/TrEMBL
  3.10.20.870 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  PFU UniProtKB/TrEMBL
  PFU_sf UniProtKB/TrEMBL
  PUL_dom UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report hgl:101708135 UniProtKB/TrEMBL
NCBI Gene Plaa ENTREZGENE
PANTHER PHOSPHOLIPASE A-2-ACTIVATING PROTEIN UniProtKB/TrEMBL
  PHOSPHOLIPASE A-2-ACTIVATING PROTEIN UniProtKB/TrEMBL
Pfam PFU UniProtKB/TrEMBL
  PUL UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PROSITE PFU UniProtKB/TrEMBL
  PUL UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0AAX6NWE2 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SKN0 ENTREZGENE, UniProtKB/TrEMBL
  G5BPW7 ENTREZGENE, UniProtKB/TrEMBL