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Gene: Plaa (phospholipase A2, activating protein) Mus musculus
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Symbol: Plaa
Name: phospholipase A2, activating protein
Description: Exhibits phospholipase A2 activator activity. Involved in several processes, including negative regulation of protein K63-linked ubiquitination; positive regulation of neurogenesis; and ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Localizes to the cytoplasm; nucleus; and synapse. Orthologous to human PLAA (phospholipase A2 activating protein); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (S)-nicotine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2410007N06; AI536418; AU018445; AW208417; D4Ertd618e; phospholipase A-2-activating protein; PLA2P; PLAP; Ufd3
Orthologs:
Homo sapiens (human) : PLAA (phospholipase A2 activating protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Plaa (phospholipase A2, activating protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plaa (phospholipase A2 activating protein)
Pan paniscus (bonobo/pygmy chimpanzee) : PLAA (phospholipase A2 activating protein)
Canis lupus familiaris (dog) : PLAA (phospholipase A2 activating protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plaa (phospholipase A2 activating protein)
Sus scrofa (pig) : PLAA (phospholipase A2 activating protein)
Chlorocebus sabaeus (green monkey) : PLAA (phospholipase A2 activating protein)
Heterocephalus glaber (naked mole-rat) : Plaa (phospholipase A2 activating protein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl494,567,514 - 94,603,244 (-)Ensembl
GRCm38494,565,139 - 94,603,247 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37494,231,830 - 94,269,938 (-)NCBIGRCm37mm9NCBIm37
MGSCv36494,061,188 - 94,095,196 (-)NCBImm8
Celera492,974,316 - 93,012,476 (-)NCBICelera
Cytogenetic Map4 C5NCBI
cM Map443.34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Plaa
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732623
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.