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Gene: Plaa (phospholipase A2, activating protein) Mus musculus
Symbol: Plaa
Name: phospholipase A2, activating protein
Description: Exhibits phospholipase A2 activator activity. Involved in several processes, including negative regulation of protein K63-linked ubiquitination; positive regulation of neurogenesis; and ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Localizes to the cytoplasm; nucleus; and synapse. Orthologous to human PLAA (phospholipase A2 activating protein); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (S)-nicotine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2410007N06; AI536418; AU018445; AW208417; D4Ertd618e; phospholipase A-2-activating protein; PLA2P; PLAP; Ufd3
Homo sapiens (human) : PLAA (phospholipase A2 activating protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Plaa (phospholipase A2, activating protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plaa (phospholipase A2 activating protein)
Pan paniscus (bonobo/pygmy chimpanzee) : PLAA (phospholipase A2 activating protein)
Canis lupus familiaris (dog) : PLAA (phospholipase A2 activating protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plaa (phospholipase A2 activating protein)
Sus scrofa (pig) : PLAA (phospholipase A2 activating protein)
Chlorocebus sabaeus (green monkey) : PLAA (phospholipase A2 activating protein)
Heterocephalus glaber (naked mole-rat) : Plaa (phospholipase A2 activating protein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl494,567,514 - 94,603,244 (-)Ensembl
GRCm38494,565,139 - 94,603,247 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37494,231,830 - 94,269,938 (-)NCBIGRCm37mm9NCBIm37
MGSCv36494,061,188 - 94,095,196 (-)NCBImm8
Celera492,974,316 - 93,012,476 (-)NCBICelera
Cytogenetic Map4 C5NCBI
cM Map443.34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Plaa
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732623
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.