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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA damage response, signal transduction resulting in transcription
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Accession:GO:0042772 term browser browse the term
Definition:A cascade of processes initiated in response to the detection of DNA damage, and resulting in the induction of transcription.


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DNA damage response, signal transduction resulting in transcription term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:17296730) UniProt PMID:17296730 NCBI chrNW_004955486:2,191,903...2,197,193
Ensembl chrNW_004955486:2,191,903...2,198,538
JBrowse link
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2 DNA repair associated acts_upstream_of_or_within ISO (PMID:8738145) MGI PMID:8738145 NCBI chrNW_004955431:13,449,287...13,526,878
Ensembl chrNW_004955431:13,449,543...13,527,432
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A acts_upstream_of_or_within ISO (PMID:10710310) MGI PMID:10710310 NCBI chrNW_004955437:6,254,638...6,261,278
Ensembl chrNW_004955437:6,254,309...6,261,479
JBrowse link
G Chek2 checkpoint kinase 2 acts_upstream_of_or_within ISO (PMID:10710310) MGI PMID:10710310 NCBI chrNW_004955455:2,969,113...3,008,004
Ensembl chrNW_004955455:2,969,270...3,003,173
JBrowse link
G Foxm1 forkhead box M1 involved_in ISO (PMID:17101782) UniProt PMID:17101782 NCBI chrNW_004955429:18,392,545...18,405,254
Ensembl chrNW_004955429:18,393,470...18,405,254
JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in ISO (PMID:14966270) UniProt PMID:14966270 NCBI chrNW_004955422:19,557,498...19,565,044
Ensembl chrNW_004955422:19,557,498...19,565,036
JBrowse link
G Rbm38 RNA binding motif protein 38 involved_in ISO (PMID:17050675) UniProt PMID:17050675 NCBI chrNW_004955445:2,036,314...2,050,882
Ensembl chrNW_004955445:2,036,124...2,052,139
JBrowse link
G Rps27l ribosomal protein S27 like involved_in ISO (PMID:18056458) UniProt PMID:18056458 NCBI chrNW_004955450:12,122,948...12,126,167
Ensembl chrNW_004955450:12,122,921...12,128,101
JBrowse link
G Rps6ka6 ribosomal protein S6 kinase A6 involved_in ISO (PMID:15042092) UniProt PMID:15042092 NCBI chrNW_004955529:3,115,652...3,296,505
Ensembl chrNW_004955529:3,149,407...3,296,105
JBrowse link
G Tfap4 transcription factor AP-4 involved_in ISO (PMID:18818310) UniProt PMID:18818310 NCBI chrNW_004955442:13,160,467...13,174,288
Ensembl chrNW_004955442:13,160,450...13,175,057
JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within
ISO (PMID:16213212)
(PMID:10710310)
(PMID:16479015)
CAFA
MGI
UniProt
PMID:10710310 PMID:16213212 PMID:16479015 NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928
JBrowse link
negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pcbp4 poly(rC) binding protein 4 acts_upstream_of_or_within ISO (PMID:20817677) MGI PMID:20817677 NCBI chrNW_004955532:3,604,720...3,615,112
Ensembl chrNW_004955532:3,603,975...3,614,290
JBrowse link
positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ing4 inhibitor of growth family member 4 involved_in ISO (PMID:15251430) UniProt PMID:15251430 NCBI chrNW_004955413:4,263,647...4,274,476
Ensembl chrNW_004955413:4,263,647...4,274,476
JBrowse link
G Rpl26 ribosomal protein L26 involved_in ISO (PMID:16213212) CAFA PMID:16213212 NCBI chrNW_004955467:8,519,760...8,525,514
Ensembl chrNW_004955467:8,519,760...8,527,182
JBrowse link
G Znf385a zinc finger protein 385A involved_in ISO (PMID:17719541) UniProt PMID:17719541 NCBI chrNW_004955458:1,610,245...1,631,639
Ensembl chrNW_004955458:1,610,245...1,631,639
JBrowse link
G Znhit1 zinc finger HIT-type containing 1 involved_in ISO (PMID:17700068) UniProt PMID:17700068 NCBI chrNW_004955456:16,070,622...16,082,286
Ensembl chrNW_004955456:16,070,622...16,082,286
JBrowse link
regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cops3 COP9 signalosome subunit 3 involved_in ISO (PMID:15861129) UniProt PMID:15861129 NCBI chrNW_004955577:639,616...664,390
Ensembl chrNW_004955577:638,749...664,390
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12572
    cellular process 12010
      signal transduction 4021
        intracellular signal transduction 2383
          signal transduction in response to DNA damage 164
            DNA damage response, signal transduction resulting in transcription 17
              DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator + 16
Path 2
Term Annotations click to browse term
  biological_process 12572
    biological regulation 9067
      regulation of biological process 8766
        signaling 4510
          signal transduction 4021
            intracellular signal transduction 2383
              signal transduction in response to DNA damage 164
                DNA damage response, signal transduction resulting in transcription 17
                  DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator + 16
paths to the root