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ONTOLOGY REPORT - ANNOTATIONS


Term:macrophage fusion
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Accession:GO:0034238 term browser browse the term
Definition:The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell.



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macrophage fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd44 CD44 molecule IMP RGD PMID:16195325 RGD:2289375 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd81 Cd81 molecule involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:12796480)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:12796480 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660
JBrowse link
negative regulation of macrophage fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stat1 signal transducer and activator of transcription 1 acts_upstream_of_or_within ISO MGI:1861949 (PMID:22865856) RGD PMID:22865856 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
positive regulation of macrophage fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam9 ADAM metallopeptidase domain 9 involved_in ISO (PMID:11831872) RGD PMID:11831872 NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917
JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein acts_upstream_of_or_within
involved_in
ISO MGI:1921864 (PMID:22865856)
(PMID:16061724), (PMID:16937266)
RGD PMID:16061724 PMID:16937266 PMID:22865856 NCBI chr 7:70,807,455...70,822,067
Ensembl chr 7:70,807,581...70,822,078
JBrowse link
G Ocstamp osteoclast stimulatory transmembrane protein acts_upstream_of_or_within ISO MGI:1923016 (PMID:22865856) RGD PMID:22865856 NCBI chr 3:154,131,113...154,141,611
Ensembl chr 3:154,132,328...154,136,991
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:18957693) RGD PMID:18957693 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISO
IBA
(PMID:18957693)
GO_REF:0000033
RGD
GO_Central
PMID:18957693 GO_REF:0000033 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20535
    cellular process 19524
      syncytium formation 68
        syncytium formation by plasma membrane fusion 66
          macrophage fusion 8
            negative regulation of macrophage fusion 1
            positive regulation of macrophage fusion 5
            regulation of macrophage fusion + 6
Path 2
Term Annotations click to browse term
  biological_process 20535
    developmental process 7103
      anatomical structure development 6605
        anatomical structure morphogenesis 3003
          anatomical structure formation involved in morphogenesis 1379
            syncytium formation 68
              syncytium formation by plasma membrane fusion 66
                macrophage fusion 8
                  negative regulation of macrophage fusion 1
                  positive regulation of macrophage fusion 5
                  regulation of macrophage fusion + 6
paths to the root