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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of toll-like receptor 4 signaling pathway
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Accession:GO:0034145 term browser browse the term
Definition:Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
Synonyms:exact_synonym: positive regulation of TLR4 signaling pathway;   positive regulation of toll-like receptor 4 signalling pathway


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positive regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in ISO (MGI:5645195|PMID:24380872) UniProt PMID:24380872 MGI:5645195 NCBI chrNW_004624743:33,372,023...33,374,438
Ensembl chrNW_004624743:33,367,898...33,373,922
JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:18622013) UniProt PMID:18622013 NCBI chrNW_004624869:1,326,605...1,337,195 JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (MGI:5788395|PMID:16267105) UniProt PMID:16267105 MGI:5788395 NCBI chrNW_004624776:7,858,400...7,862,716
Ensembl chrNW_004624776:7,793,259...7,863,184
JBrowse link
G Ifi35 interferon induced protein 35 involved_in ISO (PMID:29038465) UniProt PMID:29038465 NCBI chrNW_004624795:1,260,476...1,268,015
Ensembl chrNW_004624795:1,260,476...1,262,080
JBrowse link
G Lbp lipopolysaccharide binding protein involved_in ISO (PMID:11528597) BHF-UCL PMID:11528597 NCBI chrNW_004624842:1,306,299...1,332,269
Ensembl chrNW_004624842:1,301,831...1,332,346
JBrowse link
G LOC101722352 TIR domain-containing adapter molecule 2 involved_in ISO (PMID:22685567)
(PMID:19412184)
UniProt PMID:19412184 PMID:22685567 NCBI chrNW_004624733:6,304,454...6,341,827 JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:20345905) UniProt PMID:20345905 NCBI chrNW_004624730:74,636,554...74,656,817
Ensembl chrNW_004624730:74,636,522...74,656,886
JBrowse link
G Ninj1 ninjurin 1 involved_in ISO (MGI:6694429|PMID:25860173) UniProt PMID:25860173 MGI:6694429 NCBI chrNW_004624868:3,430,539...3,442,205
Ensembl chrNW_004624868:3,430,209...3,445,542
JBrowse link
G Nr1h3 nuclear receptor subfamily 1 group H member 3 involved_in ISO (PMID:18511497) BHF-UCL PMID:18511497 NCBI chrNW_004624767:1,459,601...1,473,224
Ensembl chrNW_004624767:1,459,601...1,467,795
JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO (PMID:19734906) MGI PMID:19734906 NCBI chrNW_004624762:9,328,275...9,382,996
Ensembl chrNW_004624762:9,328,109...9,386,067
JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA TreeGrafter
Ensembl
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624772:9,472,869...9,552,751
Ensembl chrNW_004624772:9,472,913...9,550,990
JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:19509286) BHF-UCL PMID:19509286 NCBI chrNW_004624812:433,540...445,517
Ensembl chrNW_004624812:439,319...446,646
JBrowse link
G Wdfy1 WD repeat and FYVE domain containing 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624823:1,353,601...1,405,762
Ensembl chrNW_004624823:1,353,621...1,401,160
JBrowse link
G Znrf1 zinc and ring finger 1 involved_in ISO (PMID:28593998) UniProt PMID:28593998 NCBI chrNW_004624746:11,847,627...11,954,637
Ensembl chrNW_004624746:11,848,425...11,954,784
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15093
    cellular process 14237
      signal transduction 5415
        positive regulation of signal transduction 1549
          positive regulation of pattern recognition receptor signaling pathway 65
            positive regulation of toll-like receptor 4 signaling pathway 14
Path 2
Term Annotations click to browse term
  biological_process 15093
    response to stimulus 8161
      response to external stimulus 2128
        response to external biotic stimulus 1317
          response to other organism 1314
            defense response to other organism 906
              defense response to symbiont 802
                innate immune response 664
                  regulation of innate immune response 371
                    positive regulation of innate immune response 309
                      activation of innate immune response 253
                        innate immune response-activating signaling pathway 237
                          innate immune response activating cell surface receptor signaling pathway 73
                            cell surface pattern recognition receptor signaling pathway 70
                              cell surface toll-like receptor signaling pathway 66
                                toll-like receptor 4 signaling pathway 58
                                  regulation of toll-like receptor 4 signaling pathway 29
                                    positive regulation of toll-like receptor 4 signaling pathway 14
paths to the root