ONTOLOGY REPORT - ANNOTATIONS
Term: sialyltransferase activity
Accession: GO:0008373
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Definition: Catalysis of the transfer of sialic acid to an acceptor molecule, typically the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins.
Synonyms: xref: EC:2.4.3.-; Reactome:R-HSA-9683769 "O-glycosylation of 3a is terminated"; Reactome:R-HSA-9694718 "O-glycosylation of 3a is terminated"; Reactome:R-HSA-9697018 "Addition of sialic acids on some Spike glycosyl sidechains"; Reactome:R-HSA-981814 "ST6GALNAC2 transfers sialic acid to Core 1 mucins"; Wikipedia:Sialyltransferase
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C3h20orf173
similar to human chromosome 20 open reading frame 173
enables
IEA
GO_REF:0000117
UniProt
GO_REF:0000117
NCBI chr 3:144,514,060...144,524,979
Ensembl chr 3:144,519,930...144,524,920
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Dcps
decapping enzyme, scavenger
enables
IEA
GO_REF:0000117
UniProt
GO_REF:0000117
NCBI chr 8:33,468,669...33,524,407
Ensembl chr 8:33,415,671...33,524,389
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St3gal2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
IDA
RGD
PMID:8144500
RGD:68307
NCBI chr19:38,888,851...38,939,874
Ensembl chr19:38,923,999...38,939,869
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St3gal3
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
enables
IEA IBA
GO_REF:0000117 GO_REF:0000033
UniProt GO_Central
GO_REF:0000033 GO_REF:0000117
NCBI chr 5:131,470,348...131,670,794
Ensembl chr 5:131,470,348...131,670,810
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St3gal4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
enables
IEA
GO_REF:0000117
UniProt
GO_REF:0000117
NCBI chr 8:33,415,666...33,465,319
Ensembl chr 8:33,415,671...33,524,389
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St3gal5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
enables
IEA
GO_REF:0000117
UniProt
GO_REF:0000117
NCBI chr 4:104,134,613...104,192,558
Ensembl chr 4:104,134,613...104,192,558
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St3gal6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr11:42,061,282...42,121,801
Ensembl chr11:42,077,621...42,121,776
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St6gal1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
enables
IDA ISO IEA
(PMID:21081508) (PMID:12966079) GO_REF:0000117
RGD UniProt
PMID:12966079 PMID:21081508 PMID:12626411
GO_REF:0000117, RGD:10043130
NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310
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St6gal2
ST6 beta-galactoside alpha-2,6-sialyltransferase 2
enables
ISO
(PMID:12966079)
RGD
PMID:12966079
NCBI chr 9:9,181,744...9,274,161
Ensembl chr 9:9,182,399...9,269,697
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St6galnac3
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
enables
IDA IEA ISO
GO_REF:0000117 (PMID:17123352)
UniProt RGD
PMID:17123352 PMID:8631773
GO_REF:0000117, RGD:69997
NCBI chr 2:242,129,755...242,645,120
Ensembl chr 2:242,129,763...242,645,133
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St6galnac5
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
enables
ISO
(PMID:12668675)
RGD
PMID:12668675
NCBI chr 2:241,741,933...241,911,214
Ensembl chr 2:241,742,688...241,911,208
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St6galnac6
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
enables
ISO
(PMID:17123352) (PMID:12668675)
RGD
PMID:12668675 PMID:17123352
NCBI chr 3:15,894,275...15,907,502
Ensembl chr 3:15,885,968...15,907,496
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St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
IDA
RGD
PMID:8806633
RGD:633965
NCBI chr 4:175,782,989...175,921,338
Ensembl chr 4:175,789,947...175,920,708
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St8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
TAS IMP
RGD
PMID:7685014 PMID:16887122
RGD:729711 , RGD:27372880
NCBI chr 1:127,762,573...127,838,017
Ensembl chr 1:127,762,573...127,838,091
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St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
enables
ISO
(PMID:31455764)
RGD
PMID:31455764
NCBI chr18:57,754,349...57,760,839
Ensembl chr18:57,754,347...57,760,839
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St8sia4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
enables
TAS ISO
(PMID:28810663)
RGD
PMID:28810663 PMID:9352097
RGD:634043
NCBI chr 9:95,990,131...96,084,661
Ensembl chr 9:95,993,503...96,084,653
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St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
enables
IDA
PMID:1606358
UniProt
PMID:1606358
RGD:21201272
NCBI chr18:70,736,395...70,802,537
Ensembl chr18:70,736,602...70,797,789
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St8sia6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
enables
ISO
(PMID:11980897)
RGD
PMID:11980897
NCBI chr17:76,740,755...76,884,178
Ensembl chr17:76,745,224...76,884,299
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St6galnac1
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
enables
ISO IBA
(PMID:16319059), (PMID:35303419) (PMID:10788794) GO_REF:0000033
RGD GO_Central
PMID:10788794 PMID:16319059 PMID:35303419
GO_REF:0000033
NCBI chr10:101,972,656...101,983,053
Ensembl chr10:101,972,668...101,983,053
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St6galnac2
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
enables
ISO IBA
(PMID:10742600), (PMID:29251719) GO_REF:0000033
RGD GO_Central
PMID:10742600 PMID:29251719
GO_REF:0000033
NCBI chr10:101,910,220...101,928,412
Ensembl chr10:101,909,971...101,915,008 Ensembl chr10:101,909,971...101,915,008
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St6galnac3
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 2:242,129,755...242,645,120
Ensembl chr 2:242,129,763...242,645,133
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St6galnac4
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 3:15,872,230...15,885,250
Ensembl chr 3:15,872,532...15,885,243
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St6galnac5
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
enables
IBA ISO
GO_REF:0000033 (PMID:10521438)
GO_Central RGD
PMID:10521438
GO_REF:0000033
NCBI chr 2:241,741,933...241,911,214
Ensembl chr 2:241,742,688...241,911,208
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St6galnac6
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
enables
IBA ISO
GO_REF:0000033 (PMID:10702226)
GO_Central RGD
PMID:10702226
GO_REF:0000033
NCBI chr 3:15,894,275...15,907,502
Ensembl chr 3:15,885,968...15,907,496
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St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
enables
ISO IBA
(PMID:18348864), (PMID:22885356), (PMID:8706663) GO_REF:0000033
RGD GO_Central
PMID:8706663 PMID:18348864 PMID:22885356
GO_REF:0000033
NCBI chr 4:175,782,989...175,921,338
Ensembl chr 4:175,789,947...175,920,708
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St8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
enables
ISS ISO IBA
GO_REF:0000024 (PMID:7782326), (PMID:7875291) GO_REF:0000033 (PMID:10766765), (PMID:9774483)
UniProt RGD GO_Central
PMID:7782326 PMID:7875291 PMID:9774483 PMID:10766765
GO_REF:0000024 GO_REF:0000033
NCBI chr 1:127,762,573...127,838,017
Ensembl chr 1:127,762,573...127,838,091
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St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
enables
ISO IBA
(PMID:10766765), (PMID:26192331), (PMID:9826427) (PMID:7782326) GO_REF:0000033
RGD GO_Central
PMID:7782326 PMID:9826427 PMID:10766765 PMID:26192331
GO_REF:0000033
NCBI chr18:57,754,349...57,760,839
Ensembl chr18:57,754,347...57,760,839
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St8sia4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
enables
ISO IBA
(PMID:10766765), (PMID:9774483) (PMID:8690732) GO_REF:0000033
RGD GO_Central
PMID:8690732 PMID:9774483 PMID:10766765
GO_REF:0000033
NCBI chr 9:95,990,131...96,084,661
Ensembl chr 9:95,993,503...96,084,653
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St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
enables
IBA ISO
GO_REF:0000033 (PMID:8910600)
GO_Central RGD
PMID:8910600
GO_REF:0000033
NCBI chr18:70,736,395...70,802,537
Ensembl chr18:70,736,602...70,797,789
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St8sia6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr17:76,740,755...76,884,178
Ensembl chr17:76,745,224...76,884,299
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St6galnac3
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
enables
IEA
GO_REF:0000116
RHEA
GO_REF:0000116
NCBI chr 2:242,129,755...242,645,120
Ensembl chr 2:242,129,763...242,645,133
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St3gal2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
enables
ISO IEA
(PMID:9266697) GO_REF:0000107
RGD Ensembl
PMID:9266697
GO_REF:0000107
NCBI chr19:38,888,851...38,939,874
Ensembl chr19:38,923,999...38,939,869
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St3gal4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
enables
IDA IBA ISO
GO_REF:0000033 (PMID:8288606)
GO_Central RGD
PMID:8288606 PMID:2262006
GO_REF:0000033, RGD:4140423
NCBI chr 8:33,415,666...33,465,319
Ensembl chr 8:33,415,671...33,524,389
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St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
enables
ISO IBA
(PMID:14722111), (PMID:8027041) MGI:2387752 (PMID:12068010), (PMID:8144500), (PMID:8375377), (PMID:9184827) GO_REF:0000033 (PMID:19820709)
RGD GO_Central
PMID:8027041 PMID:8144500 PMID:8375377 PMID:9184827 PMID:12068010 PMID:14722111 PMID:19820709 More...
GO_REF:0000033
NCBI chr 7:98,845,270...98,913,409
Ensembl chr 7:98,845,270...98,913,236
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St3gal2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
enables
ISO IBA IEA IDA
(PMID:12716912), (PMID:25916169), (PMID:8920913), (PMID:9266697) (PMID:8144500), (PMID:9184827) GO_REF:0000033 GO_REF:0000117
RGD GO_Central UniProt
PMID:8144500 PMID:8920913 PMID:9184827 PMID:9266697 PMID:12716912 PMID:25916169 PMID:8144500 More...
GO_REF:0000033 GO_REF:0000117, RGD:68307
NCBI chr19:38,888,851...38,939,874
Ensembl chr19:38,923,999...38,939,869
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St3gal3
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
enables
IEA ISO
GO_REF:0000107 (PMID:9184827)
Ensembl RGD
PMID:9184827
GO_REF:0000107
NCBI chr 5:131,470,348...131,670,794
Ensembl chr 5:131,470,348...131,670,810
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St3gal4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
enables
ISO IBA
(PMID:8288606) (PMID:9184827) GO_REF:0000033
RGD GO_Central
PMID:8288606 PMID:9184827
GO_REF:0000033
NCBI chr 8:33,415,666...33,465,319
Ensembl chr 8:33,415,671...33,524,389
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St6gal1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
enables
ISO IBA ISS
(PMID:23999306) MGI:2387745 (PMID:12068010), (PMID:22039275) GO_REF:0000033 GO_REF:0000024
RGD GO_Central UniProt
PMID:12068010 PMID:22039275 PMID:23999306
GO_REF:0000024 GO_REF:0000033
NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310
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St6gal2
ST6 beta-galactoside alpha-2,6-sialyltransferase 2
enables
ISO IBA ISS
(PMID:12235148) GO_REF:0000033 GO_REF:0000024
RGD GO_Central UniProt
PMID:12235148
GO_REF:0000024 GO_REF:0000033
NCBI chr 9:9,181,744...9,274,161
Ensembl chr 9:9,182,399...9,269,697
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St3gal5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
enables
ISO ISS IEA IBA
(PMID:9822625) GO_REF:0000024 GO_REF:0000107 GO_REF:0000033
RGD UniProt Ensembl GO_Central
PMID:9822625
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107
NCBI chr 4:104,134,613...104,192,558
Ensembl chr 4:104,134,613...104,192,558
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St3gal3
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
TAS
RGD
PMID:1400416
RGD:68308
NCBI chr 5:131,470,348...131,670,794
Ensembl chr 5:131,470,348...131,670,810
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St3gal4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
enables
ISS ISO
GO_REF:0000024 (PMID:12097641) (PMID:25498912), (PMID:8611500)
UniProt RGD
PMID:8611500 PMID:12097641 PMID:25498912
GO_REF:0000024
NCBI chr 8:33,415,666...33,465,319
Ensembl chr 8:33,415,671...33,524,389
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St3gal6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
enables
IEA ISO ISS
GO_REF:0000107 (PMID:10206952) GO_REF:0000024
Ensembl RGD UniProt
PMID:10206952
GO_REF:0000024 GO_REF:0000107
NCBI chr11:42,061,282...42,121,801
Ensembl chr11:42,077,621...42,121,776
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
molecular_function
20626
catalytic activity
6028
transferase activity
2396
glycosyltransferase activity
284
sialyltransferase activity
22
N-acetyllactosaminide alpha-2,3-sialyltransferase activity
3
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity
6
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity
6
alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity
1
beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase
2
beta-galactoside (CMP) alpha-2,3-sialyltransferase activity
4
beta-galactoside alpha-2,3-sialyltransferase activity
0
beta-galactoside alpha-2,6-sialyltransferase activity
2
galactosyldiacylglycerol alpha-2,3-sialyltransferase activity
0
lactosylceramide alpha-2,3-sialyltransferase activity
1