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ONTOLOGY REPORT - ANNOTATIONS

Term:alcohol dehydrogenase (NADP+) activity
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Accession:GO:0008106 term browser browse the term
Definition:Catalysis of the reaction: an alcohol + NADP+ = an aldehyde or ketone + NADPH + H+.
Synonyms:exact_synonym: NADP-aldehyde reductase activity
 related_synonym: aldehyde reductase (NADPH) activity
 xref: EC:1.1.1.2

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alcohol dehydrogenase (NADP+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 NCBI chrNW_004624906:1,463,201...1,474,001
Ensembl chrNW_004624906:1,462,693...1,474,214 		JBrowse link
G Rdh14 retinol dehydrogenase 14 enables ISO (PMID:25533474) MGI PMID:25533474 NCBI chrNW_004624738:1,393,157...1,397,587 JBrowse link
aldose reductase (NADPH) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 enables ISO (PMID:14667815), (PMID:15769935) MGI PMID:14667815 PMID:15769935 NCBI chrNW_004624906:1,463,201...1,474,001
Ensembl chrNW_004624906:1,462,693...1,474,214 		JBrowse link
G LOC101720124 aldose reductase enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004624783:1,945,173...1,958,073
Ensembl chrNW_004624783:1,945,073...1,958,155 		JBrowse link
all-trans-retinol dehydrogenase (NADP+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhrs3 dehydrogenase/reductase 3 enables ISO (PMID:24005908) MGI PMID:24005908 NCBI chrNW_004624818:557,399...590,872
Ensembl chrNW_004624818:557,409...590,872 		JBrowse link
G Dhrs7 dehydrogenase/reductase 7 enables ISO (PMID:26466768) UniProt PMID:26466768 NCBI chrNW_004624734:40,994,786...41,006,001
Ensembl chrNW_004624734:40,993,587...41,006,074 		JBrowse link
G Rdh10 retinol dehydrogenase 10 enables IEA UniProt GO_REF:0000003 NCBI chrNW_004624744:17,838,047...17,868,423
Ensembl chrNW_004624744:17,837,609...17,868,431 		JBrowse link
G Rdh11 retinol dehydrogenase 11 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004624734:33,283,336...33,295,797
Ensembl chrNW_004624734:33,283,497...33,295,091 		JBrowse link
G Rdh12 retinol dehydrogenase 12 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004624734:33,256,469...33,266,085
Ensembl chrNW_004624734:33,254,432...33,266,140 		JBrowse link
G Rdh13 retinol dehydrogenase 13 enables ISO (PMID:18039331) UniProt PMID:18039331 NCBI chrNW_004624832:2,141,906...2,159,009
Ensembl chrNW_004624832:2,141,902...2,159,009 		JBrowse link
G Rdh14 retinol dehydrogenase 14 enables ISO (PMID:12435598)
(PMID:12226107)		 UniProt PMID:12226107 PMID:12435598 NCBI chrNW_004624738:1,393,157...1,397,587 JBrowse link
carbonyl reductase (NADPH) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbr3 carbonyl reductase 3 enables ISO
IEA		 RGD
UniProt
TreeGrafter		 PMID:18983987 GO_REF:0000104 GO_REF:0000118 RGD:2316293 NCBI chrNW_004624745:27,298,714...27,305,606
Ensembl chrNW_004624745:27,294,222...27,305,109 		JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624801:10,866,264...10,868,064
Ensembl chrNW_004624801:10,865,219...10,868,060 		JBrowse link
G Dhrs1 dehydrogenase/reductase 1 enables ISO (PMID:30031147) UniProt PMID:30031147 NCBI chrNW_004624820:8,204,627...8,213,512 JBrowse link
G Dhrs7 dehydrogenase/reductase 7 enables ISO (PMID:24246760), (PMID:26466768), (PMID:28457967), (PMID:28687384) UniProt PMID:24246760 PMID:26466768 PMID:28457967 PMID:28687384 NCBI chrNW_004624734:40,994,786...41,006,001
Ensembl chrNW_004624734:40,993,587...41,006,074 		JBrowse link
G LOC101705747 dehydrogenase/reductase SDR family member 2, mitochondrial enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624820:8,570,571...8,579,181
Ensembl chrNW_004624820:8,570,571...8,579,127 		JBrowse link
G LOC101706828 dehydrogenase/reductase SDR family member 2, mitochondrial enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624820:8,962,242...8,969,677 JBrowse link
G LOC101707305 carbonyl reductase [NADPH] 1-like enables IEA TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000118 NCBI chrNW_004624745:24,148,788...24,151,713 JBrowse link
G LOC101707667 carbonyl reductase [NADPH] 1-like enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624745:24,142,431...24,143,466 JBrowse link
G LOC101708169 dehydrogenase/reductase SDR family member 4 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624820:8,478,036...8,490,227
Ensembl chrNW_004624820:8,477,878...8,490,533 		JBrowse link
G LOC101709698 carbonyl reductase [NADPH] 1 enables IEA UniProt
TreeGrafter		 GO_REF:0000104 GO_REF:0000118 NCBI chrNW_004624745:24,222,736...24,247,542 JBrowse link
G LOC101726221 carbonyl reductase [NADPH] 2-like enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624801:10,870,138...10,872,337 JBrowse link
G LOC110348651 carbonyl reductase [NADPH] 3-like enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624745:24,137,464...24,138,377 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18442
    catalytic activity 5600
      oxidoreductase activity 698
        oxidoreductase activity, acting on CH-OH group of donors 116
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 107
            alcohol dehydrogenase [NAD(P)+] activity 35
              aldo-keto reductase (NADPH) activity 23
                alcohol dehydrogenase (NADP+) activity 20
                  2-methylbutanal reductase (NADPH) activity 0
                  3-methylbutanal reductase (NADPH) activity 0
                  aldose reductase (NADPH) activity + 2
                  all-trans-retinol dehydrogenase (NADP+) activity 7
                  carbonyl reductase (NADPH) activity 12
paths to the root