all-trans-retinol dehydrogenase (NADP+) activity - Ontology Browser

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all-trans-retinol dehydrogenase (NADP+) activity (GO:0052650)
Annotations: Rat: (10) Mouse: (14) Human: (13) Chinchilla: (4) Bonobo: (9) Dog: (7) Squirrel: (6) Pig: (11) Naked Mole-rat: (6) Green Monkey: (7)

Parent Terms

Term With Siblings

Child Terms

2-methylbutanal reductase (NADPH) activity

3-methylbutanal reductase (NADPH) activity

aldose reductase (NADPH) activity +

all-trans-retinol dehydrogenase (NADP+) activity

Catalysis of the reaction: all-trans-retinol + NADP+ = all-trans-retinal + NADPH + H+.

Synonyms
Broad Synonyms:	all-trans retinal reductase activity ; all-trans-retinol dehydrogenase activity ; retinol dehydrogenase activity
Related Synonyms:	NADP(H)-dependent retinol dehydrogenase/reductase activity ; retinol dehydrogenase [NADP+] activity ; retinol:NADP+ oxidoreductase activity
Xrefs:	EC:1.1.1.300 ; KEGG_REACTION:R08379 ; MetaCyc:RXN-10841 ; RHEA:25033 ; Reactome:R-HSA-2466861 "Defective RDH12 does not reduce atRAL to atROL and causes LCA13" ; Reactome:R-HSA-2471670 "Defective RDH12 does not reduce atRAL to atROL" ; reactome:R-HSA-2464803 "RDH8 reduces atRAL to atROL" ; reactome:R-HSA-2464822 "RDH12 reduces atRAL to atROL" ; reactome:R-HSA-2465921 "11cRDH oxidises 11cROL to 11cRAL" ; reactome:R-HSA-2465940 "atRAL is reduced to atROL" ; reactome:R-HSA-5419165 "RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL" ; reactome:R-HSA-5615668 "AKR1C3 reduces atRAL to atROL" ; reactome:R-HSA-5623643 "RDH13 reduces atRAL to atROL" ; reactome:R-HSA-74872 "RDH10,11 oxidise 11cROL to 11cRAL"
Definition Sources:	RHEA:25033

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