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ONTOLOGY REPORT - ANNOTATIONS


Term:alditol:NADP+ 1-oxidoreductase activity
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Accession:GO:0004032 term browser browse the term
Definition:Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+.
Synonyms:exact_synonym: aldehyde reductase activity;   aldose reductase activity
 related_synonym: polyol dehydrogenase (NADP(+)) activity
 xref: EC:1.1.1.21;   KEGG_REACTION:R02820;   MetaCyc:ALDEHYDE-REDUCTASE-RXN;   RHEA:12789;   reactome:R-HSA-196060 "Reduction of isocaproaldehyde to 4-methylpentan-1-ol";   reactome:R-HSA-5652172 "AKR1B1 reduces Glc to D-sorbitol"


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alditol:NADP+ 1-oxidoreductase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide JBrowse link 2 243,702,035 243,720,063 RGD:1624291
G Akr1a1 aldo-keto reductase family 1 member A1 JBrowse link 5 135,482,068 135,498,693 RGD:1624291
RGD:13792537
G Akr1b1 aldo-keto reductase family 1 member B JBrowse link 4 61,706,866 61,720,959 RGD:1626085
RGD:13792537
RGD:1624291
G Akr1b10 aldo-keto reductase family 1 member B10 JBrowse link 4 61,813,265 61,830,371 RGD:6903952
RGD:13792537
G Akr1b7 aldo-keto reductase family 1, member B7 JBrowse link 4 61,850,256 61,879,733 RGD:628357
RGD:13792537
G Akr1b8 aldo-keto reductase family 1, member B8 JBrowse link 4 61,772,064 61,784,637 RGD:13792537
G Akr1c1 aldo-keto reductase family 1, member C1 JBrowse link 17 69,441,253 69,460,334 RGD:13792537
G Akr1c12 aldo-keto reductase family 1, member C12 JBrowse link 17 69,695,532 69,711,654 RGD:13792537
G Akr1c12l1 aldo-keto reductase family 1, member C12-like 1 JBrowse link 17 69,588,119 69,599,168 RGD:13792537
G Akr1c13 aldo-keto reductase family 1, member C13 JBrowse link 17 69,614,323 69,647,772 RGD:13792537
G Akr1c14 aldo-keto reductase family 1, member C14 JBrowse link 17 69,806,095 69,827,125 RGD:13792537
G Akr1c15 aldo-keto reductase family 1, member C15 JBrowse link 17 69,835,338 69,862,093 RGD:13792537
G Akr1c19 aldo-keto reductase family 1, member C19 JBrowse link 17 69,653,003 69,675,204 RGD:13792537
G Akr1c2 aldo-keto reductase family 1, member C2 JBrowse link 17 69,388,337 69,435,160 RGD:1624291
RGD:13792537
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:10053609
RGD:13792537
RGD:1624291
G Akr1d1 aldo-keto reductase family 1, member D1 JBrowse link 4 65,110,706 65,143,930 RGD:13792537
G Akr1e2 aldo-keto reductase family 1, member E2 JBrowse link 17 69,365,437 69,379,944 RGD:13792537
G Akr7a2 aldo-keto reductase family 7, member A2 JBrowse link 5 157,759,448 157,768,473 RGD:625492
G LOC100910708 aldose reductase-related protein 1-like JBrowse link 4 62,015,923 62,031,795 RGD:13792537
G RGD1564865 similar to 20-alpha-hydroxysteroid dehydrogenase JBrowse link 17 69,468,427 69,497,132 RGD:13792537

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Term Annotations click to browse term
  molecular_function 20377
    catalytic activity 6066
      oxidoreductase activity 867
        oxidoreductase activity, acting on CH-OH group of donors 149
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 138
            aldo-keto reductase (NADP) activity 33
              alcohol dehydrogenase (NADP+) activity 28
                alditol:NADP+ 1-oxidoreductase activity 20
                  D-xylose:NADP reductase activity 0
                  L-arabinose:NADP reductase activity 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.