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ONTOLOGY REPORT - ANNOTATIONS

Term:solute:inorganic anion antiporter activity
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Accession:GO:0005452 term browser browse the term
Definition:Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: inorganic anion(out) + solute(in) = inorganic anion (in) + solute(out).
Synonyms:exact_synonym: inorganic anion exchanger activity
 xref: Reactome:R-HSA-1247665 "SLC4A1 exchanges cytosolic Cl- for extracellular HCO3-";   Reactome:R-HSA-5627737 "SLC26A3 does not exchange Cl- for HCO3-";   Reactome:R-HSA-5656248 "Defective SLC4A1 does not exchange Cl- for HCO3- (in erythrocytes)";   reactome:R-HSA-1237038 "SLC4A1 exchanges cytosolic HCO3- for extracellular Cl-";   reactome:R-HSA-425482 "SLC4A1,2,3 exchanges HCO3- for Cl-";   reactome:R-HSA-425577 "Na+-driven Cl-/HCO3- exchanger transport";   reactome:R-HSA-427666 "SLC26A3,6 exchange Cl- for HCO3-"


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solute:inorganic anion antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC22A11 solute carrier family 22 member 11 enables IDA (PMID:15037815) UniProt PMID:15037815 NCBI chr11:64,555,941...64,572,875
Ensembl chr11:64,555,690...64,572,875 		JBrowse link
G SLC22A6 solute carrier family 22 member 6 enables IDA (PMID:15037815) UniProt PMID:15037815 NCBI chr11:62,976,597...62,984,967
Ensembl chr11:62,936,385...62,984,967 		JBrowse link
G SLC22A8 solute carrier family 22 member 8 enables IDA (PMID:15037815) UniProt PMID:15037815 NCBI chr11:62,992,824...63,015,841
Ensembl chr11:62,989,154...63,015,841 		JBrowse link
G SLC25A14 solute carrier family 25 member 14 enables IDA (PMID:31356773) UniProt PMID:31356773 NCBI chr  X:130,339,919...130,373,357
Ensembl chr  X:130,339,888...130,373,361 		JBrowse link
G SLC25A30 solute carrier family 25 member 30 enables IDA (PMID:31356773) UniProt PMID:31356773 NCBI chr13:45,393,316...45,434,016
Ensembl chr13:45,393,316...45,418,455 		JBrowse link
G SLC26A1 solute carrier family 26 member 1 enables IDA (PMID:12713736), (PMID:27125215) UniProt PMID:12713736 PMID:27125215 NCBI chr 4:978,991...993,404
Ensembl chr 4:979,073...993,440 		JBrowse link
G SLC26A2 solute carrier family 26 member 2 enables IEA
IDA		 (PMID:20219950) Ensembl
UniProt		 PMID:20219950 GO_REF:0000107 NCBI chr 5:149,960,758...149,987,400
Ensembl chr 5:149,960,758...149,993,455 		JBrowse link
G SLC26A3 solute carrier family 26 member 3 enables TAS Reactome Reactome:R-HSA-427666 Reactome:R-HSA-5627737 NCBI chr 7:107,765,469...107,803,223
Ensembl chr 7:107,765,467...107,803,225 		JBrowse link
G SLC26A6 solute carrier family 26 member 6 enables TAS
IDA
IEA
IMP
ISS		 (PMID:15548529), (PMID:27681177)
(PMID:20501439)		 Reactome
GO_Central
Ensembl
UniProt		 PMID:15548529 PMID:20501439 PMID:27681177 GO_REF:0000024 GO_REF:0000107 Reactome:R-HSA-427666 NCBI chr 3:48,625,723...48,635,461
Ensembl chr 3:48,625,723...48,635,493 		JBrowse link
G SLC26A9 solute carrier family 26 member 9 enables IDA (PMID:15800055), (PMID:22544634) UniProt PMID:15800055 PMID:22544634 NCBI chr 1:205,913,052...205,943,456
Ensembl chr 1:205,913,048...205,943,460 		JBrowse link
G SLC4A1 solute carrier family 4 member 1 (Diego blood group) enables IEA
IDA
TAS		 (PMID:14734552), (PMID:24121512) InterPro
UniProt
Reactome		 PMID:14734552 PMID:24121512 GO_REF:0000002 Reactome:R-HSA-425482 Reactome:R-HSA-5656248 NCBI chr17:44,248,390...44,268,135
Ensembl chr17:44,248,390...44,268,141 		JBrowse link
G SLC4A10 solute carrier family 4 member 10 enables TAS
IEA		 Reactome
InterPro		 GO_REF:0000002 Reactome:R-HSA-425577 NCBI chr 2:161,624,416...161,985,270
Ensembl chr 2:161,424,332...161,985,282 		JBrowse link
G SLC4A11 solute carrier family 4 member 11 enables IEA InterPro GO_REF:0000002 NCBI chr20:3,227,417...3,239,559
Ensembl chr20:3,227,417...3,239,559 		JBrowse link
G SLC4A2 solute carrier family 4 member 2 enables IEA
TAS		 InterPro
Reactome		 GO_REF:0000002 Reactome:R-HSA-425482 NCBI chr 7:151,058,200...151,076,527
Ensembl chr 7:151,057,210...151,076,526 		JBrowse link
G SLC4A3 solute carrier family 4 member 3 enables IEA
TAS		 (PMID:7923606) InterPro
PINC		 PMID:7923606 GO_REF:0000002 Reactome:R-HSA-425482 NCBI chr 2:219,627,630...219,641,971
Ensembl chr 2:219,627,394...219,641,980 		JBrowse link
G SLC4A4 solute carrier family 4 member 4 enables IEA InterPro GO_REF:0000002 NCBI chr 4:71,062,660...71,572,083
Ensembl chr 4:71,062,667...71,572,087 		JBrowse link
G SLC4A5 solute carrier family 4 member 5 enables IEA InterPro GO_REF:0000002 NCBI chr 2:74,216,242...74,343,416
Ensembl chr 2:74,216,242...74,343,416 		JBrowse link
G SLC4A7 solute carrier family 4 member 7 enables IEA InterPro GO_REF:0000002 NCBI chr 3:27,372,723...27,484,384
Ensembl chr 3:27,372,723...27,484,420 		JBrowse link
G SLC4A8 solute carrier family 4 member 8 enables IEA
TAS		 InterPro
Reactome		 GO_REF:0000002 Reactome:R-HSA-425577 NCBI chr12:51,391,446...51,515,763
Ensembl chr12:51,391,317...51,515,763 		JBrowse link
G SLC4A9 solute carrier family 4 member 9 enables IEA InterPro GO_REF:0000002 NCBI chr 5:140,360,194...140,375,141
Ensembl chr 5:140,360,194...140,375,141 		JBrowse link
ADP:phosphate antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC25A23 solute carrier family 25 member 23 enables IDA (PMID:15123600) UniProt PMID:15123600 NCBI chr19:6,436,081...6,459,792
Ensembl chr19:6,436,079...6,465,203 		JBrowse link
G SLC25A24 solute carrier family 25 member 24 enables IDA (PMID:15123600) UniProt PMID:15123600 NCBI chr 1:108,134,043...108,200,343
Ensembl chr 1:108,134,043...108,200,849 		JBrowse link
ATP:phosphate antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC25A23 solute carrier family 25 member 23 enables IDA (PMID:15123600) UniProt PMID:15123600 NCBI chr19:6,436,081...6,459,792
Ensembl chr19:6,436,079...6,465,203 		JBrowse link
G SLC25A24 solute carrier family 25 member 24 enables IDA (PMID:15123600) UniProt PMID:15123600 NCBI chr 1:108,134,043...108,200,343
Ensembl chr 1:108,134,043...108,200,849 		JBrowse link
G SLC25A25 solute carrier family 25 member 25 enables IDA (PMID:34346195) UniProt PMID:34346195 NCBI chr 9:128,068,232...128,109,245
Ensembl chr 9:128,068,201...128,109,245 		JBrowse link
chloride:bicarbonate antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC26A11 solute carrier family 26 member 11 enables ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:80,220,427...80,253,500
Ensembl chr17:80,219,699...80,253,509 		JBrowse link
G SLC26A3 solute carrier family 26 member 3 enables IDA
IEA		 (PMID:16606687), (PMID:19321737), (PMID:22159084), (PMID:22627094) UniProt
Ensembl		 PMID:16606687 PMID:19321737 PMID:22159084 PMID:22627094 GO_REF:0000107 NCBI chr 7:107,765,469...107,803,223
Ensembl chr 7:107,765,467...107,803,225 		JBrowse link
G SLC26A4 solute carrier family 26 member 4 enables IDA
IMP
IEA		 (PMID:35601831)
(PMID:24051746)		 UniProt
Ensembl		 PMID:24051746 PMID:35601831 GO_REF:0000107 NCBI chr 7:107,660,828...107,717,809
Ensembl chr 7:107,660,828...107,717,809 		JBrowse link
G SLC26A5 solute carrier family 26 member 5 enables ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:103,352,730...103,446,207
Ensembl chr 7:103,352,730...103,446,207 		JBrowse link
G SLC26A6 solute carrier family 26 member 6 enables IEA
IDA		 (PMID:12444019), (PMID:15990874), (PMID:20501439) Ensembl
UniProt		 PMID:12444019 PMID:15990874 PMID:20501439 GO_REF:0000107 NCBI chr 3:48,625,723...48,635,461
Ensembl chr 3:48,625,723...48,635,493 		JBrowse link
G SLC26A7 solute carrier family 26 member 7 enables IDA
IEA		 (PMID:12736153), (PMID:32119864) UniProt
Ensembl		 PMID:12736153 PMID:32119864 GO_REF:0000107 NCBI chr 8:91,209,496...91,398,155
Ensembl chr 8:91,209,494...91,398,155 		JBrowse link
G SLC26A9 solute carrier family 26 member 9 enables ISO (PMID:15800055) MGI PMID:15800055 NCBI chr 1:205,913,052...205,943,456
Ensembl chr 1:205,913,048...205,943,460 		JBrowse link
G SLC4A1 solute carrier family 4 member 1 (Diego blood group) enables IDA
IEA		 (PMID:28387307) UniProt
Ensembl		 PMID:28387307 GO_REF:0000107 NCBI chr17:44,248,390...44,268,135
Ensembl chr17:44,248,390...44,268,141 		JBrowse link
G SLC4A2 solute carrier family 4 member 2 enables IDA
IMP
IEA		 (PMID:15184086)
(PMID:34668226)		 UniProt
Ensembl		 PMID:15184086 PMID:34668226 GO_REF:0000107 NCBI chr 7:151,058,200...151,076,527
Ensembl chr 7:151,057,210...151,076,526 		JBrowse link
G SLC4A3 solute carrier family 4 member 3 enables IEA
IDA		 (PMID:7923606) Ensembl
UniProt		 PMID:7923606 GO_REF:0000107 NCBI chr 2:219,627,630...219,641,971
Ensembl chr 2:219,627,394...219,641,980 		JBrowse link
G SLC4A9 solute carrier family 4 member 9 enables IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:140,360,194...140,375,141
Ensembl chr 5:140,360,194...140,375,141 		JBrowse link
glucose 6-phosphate:phosphate antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC37A1 solute carrier family 37 member 1 enables IEA
IBA
IDA
EXP		 (PMID:21949678) InterPro
GO_Central
UniProt
Reactome		 PMID:21949678 GO_REF:0000002 GO_REF:0000033 NCBI chr21:42,499,622...42,581,426
Ensembl chr21:42,496,008...42,581,440 		JBrowse link
G SLC37A2 solute carrier family 37 member 2 enables IDA
IBA
EXP
IEA		 (PMID:21949678) UniProt
GO_Central
Reactome
InterPro		 PMID:21949678 GO_REF:0000002 GO_REF:0000033 NCBI chr11:125,063,305...125,090,516
Ensembl chr11:125,063,302...125,090,516 		JBrowse link
G SLC37A3 solute carrier family 37 member 3 NOT|enables IDA (PMID:21949678) UniProt PMID:21949678 NCBI chr 7:140,333,752...140,398,530
Ensembl chr 7:140,293,693...140,404,433 		JBrowse link
G SLC37A4 solute carrier family 37 member 4 enables EXP
IBA
TAS
IDA
IEA		 (PMID:18337460)
(PMID:18337460), (PMID:21949678)		 Reactome
GO_Central
MGI
Ensembl		 PMID:18337460 PMID:21949678 GO_REF:0000033 GO_REF:0000107 Reactome:R-HSA-3229118 NCBI chr11:119,024,112...119,030,877
Ensembl chr11:119,023,751...119,030,906 		JBrowse link
sodium,bicarbonate:chloride antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC4A10 solute carrier family 4 member 10 enables IEA Ensembl GO_REF:0000107 NCBI chr 2:161,624,416...161,985,270
Ensembl chr 2:161,424,332...161,985,282 		JBrowse link
G SLC4A8 solute carrier family 4 member 8 enables IDA
IEA		 (PMID:11133997), (PMID:18577713) UniProt
Ensembl		 PMID:11133997 PMID:18577713 GO_REF:0000107 NCBI chr12:51,391,446...51,515,763
Ensembl chr12:51,391,317...51,515,763 		JBrowse link
G SLC4A9 solute carrier family 4 member 9 enables IEA Ensembl GO_REF:0000107 NCBI chr 5:140,360,194...140,375,141
Ensembl chr 5:140,360,194...140,375,141 		JBrowse link
sulfate:bicarbonate antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC26A1 solute carrier family 26 member 1 enables ISS UniProt GO_REF:0000024 NCBI chr 4:978,991...993,404
Ensembl chr 4:979,073...993,440 		JBrowse link
G SLC26A6 solute carrier family 26 member 6 enables IDA (PMID:12444019) UniProt PMID:12444019 NCBI chr 3:48,625,723...48,635,461
Ensembl chr 3:48,625,723...48,635,493 		JBrowse link
sulfate:chloride antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC26A8 solute carrier family 26 member 8 enables IDA (PMID:11278976) UniProt PMID:11278976 NCBI chr 6:35,943,516...36,024,641
Ensembl chr 6:35,943,516...36,024,868 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19548
    transporter activity 1302
      transmembrane transporter activity 1183
        inorganic molecular entity transmembrane transporter activity 763
          inorganic anion transmembrane transporter activity 170
            solute:inorganic anion antiporter activity 32
              chloride:bicarbonate antiporter activity + 13
              chloride:proton antiporter activity 0
              dicarboxylate:phosphate antiporter activity 0
              organophosphate:phosphate antiporter activity + 7
              oxalate:chloride antiporter activity 0
              sulfate:bicarbonate antiporter activity 2
              sulfate:chloride antiporter activity 1
Path 2
Term Annotations click to browse term
  molecular_function 19548
    transporter activity 1302
      transmembrane transporter activity 1183
        active transmembrane transporter activity 466
          secondary active transmembrane transporter activity 291
            antiporter activity 137
              solute:inorganic anion antiporter activity 32
                chloride:bicarbonate antiporter activity + 13
                chloride:proton antiporter activity 0
                dicarboxylate:phosphate antiporter activity 0
                organophosphate:phosphate antiporter activity + 7
                oxalate:chloride antiporter activity 0
                sulfate:bicarbonate antiporter activity 2
                sulfate:chloride antiporter activity 1
paths to the root