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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:dengue hemorrhagic fever
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Accession:DOID:12206 term browser browse the term
Definition:A dengue disease that occurs when a person experiences a second infection with a heterologous Dengue virus serotype, which is transmitted_by Aedes mosquito bite. The infection has_symptom hemorrhagic lesions of the skin, has_symptom thrombocytopenia, has_symptom reduction in the fluid part of the blood, and has_symptom high fever. (DO)
Synonyms:exact_synonym: DHF;   Hemorrhagic Dengues;   Philippine Hemorrhagic Fever;   Severe Dengue;   Severe Dengues;   Singapore hemorrhagic fever;   Thai hemorrhagic fever;   dengue haemorrhagic fever;   hemorrhagic dengue
 primary_id: MESH:D019595
 xref: EFO:0004227;   ICD10CM:A91;   NCI:C34683
For additional species annotation, visit the Alliance of Genome Resources.

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dengue hemorrhagic fever term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec5a C-type lectin domain containing 5A ISO CTD Direct Evidence: therapeutic CTD PMID:18496526 NCBI chrNW_004936592:5,733,592...5,741,573
Ensembl chrNW_004936592:5,733,332...5,741,047 		JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa susceptibility ISO DNA:polymorphism:cds:p.H131R(human) RGD PMID:22817980 RGD:11040906 NCBI chrNW_004937131:15,542...22,099 JBrowse link
G Il21 interleukin 21 severity ISO protein:increased expression:blood serum (human) RGD PMID:24858204 RGD:127285368 NCBI chrNW_004936662:1,689,879...1,696,883
Ensembl chrNW_004936662:1,689,879...1,696,883 		JBrowse link
G Osbp oxysterol binding protein ISO mRNA:increased expression:peripheral blood mononuclear cell RGD PMID:28241052 RGD:41404654 NCBI chrNW_004936581:3,118,198...3,148,882
Ensembl chrNW_004936581:3,118,192...3,149,005 		JBrowse link
G Plce1 phospholipase C epsilon 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22001756 NCBI chrNW_004936601:817,151...1,105,824
Ensembl chrNW_004936601:816,190...1,105,830 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 severity ISO DNA;polymorphism:5'utr: (rs25531) (human) RGD PMID:30452889 RGD:38676265 NCBI chrNW_004936538:6,205,268...6,239,062
Ensembl chrNW_004936538:6,205,251...6,239,083 		JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member susceptibility ISO DNA:SNPs: : RGD PMID:18071882 RGD:6482261 NCBI chrNW_004936476:25,913,699...25,923,419
Ensembl chrNW_004936476:25,913,663...25,923,427 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16465
    disease by infectious agent 1968
      viral infectious disease 1499
        Arbovirus Infections 46
          dengue disease 14
            dengue hemorrhagic fever 7
              dengue shock syndrome 0
Path 2
Term Annotations click to browse term
  disease 16465
    disease by infectious agent 1968
      viral infectious disease 1499
        RNA Virus Infections 1265
          Flaviviridae Infections 128
            Flavivirus Infections 36
              dengue disease 14
                dengue hemorrhagic fever 7
                  dengue shock syndrome 0
paths to the root