Slc6a4 (solute carrier family 6 member 4)

Gene: Slc6a4 (solute carrier family 6 member 4) Ictidomys tridecemlineatus

Analyze

Symbol:

Slc6a4

Name:

solute carrier family 6 member 4

RGD ID:

12681524

Description:

ENCODES a protein that exhibits actin filament binding (ortholog); cocaine binding (ortholog); identical protein binding (ortholog); INVOLVED IN behavioral response to cocaine (ortholog); cellular response to cGMP (ortholog); cellular response to organic substance (ortholog); PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH AIDS Dementia Complex (ortholog); alcohol dependence (ortholog); alcohol use disorder (ortholog); FOUND IN postsynaptic membrane (ortholog); presynaptic membrane (ortholog); serotonergic synapse (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

sodium-dependent serotonin transporter

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	43,327,307 - 43,361,581 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936538	6,205,251 - 6,239,083 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936538	6,205,268 - 6,239,062 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

AIDS Dementia Complex (ISO)

alcohol dependence (ISO)

alcohol use disorder (ISO)

alexithymia (ISO)

amphetamine abuse (ISO)

anxiety disorder (ISO)

Asperger syndrome (ISO)

asthma (ISO)

attention deficit hyperactivity disorder (ISO)

autism spectrum disorder (ISO)

autistic disorder (ISO)

bipolar disorder (ISO)

borna disease (ISO)

brain disease (ISO)

Burns (ISO)

chronic fatigue syndrome (ISO)

Chronic Hepatitis C (ISO)

chronic obstructive pulmonary disease (ISO)

Cocaine-Related Disorders (ISO)

cognitive disorder (ISO)

conduct disorder (ISO)

congenital diaphragmatic hernia (ISO)

congestive heart failure (ISO)

dengue hemorrhagic fever (ISO)

depressive disorder (ISO)

diverticulitis (ISO)

Dyspepsia (ISO)

Escherichia Coli Infections (ISO)

fetal alcohol spectrum disorder (ISO)

generalized anxiety disorder (ISO)

genetic disease (ISO)

Gram-Negative Bacterial Infections (ISO)

heart disease (ISO)

Helicobacter Infections (ISO)

Hypoxia (ISO)

leishmaniasis (ISO)

liver cirrhosis (ISO)

major depressive disorder (ISO)

Memory Disorders (ISO)

mood disorder (ISO)

neurofibromatosis 1 (ISO)

obsessive-compulsive disorder (ISO)

obstructive sleep apnea (ISO)

Parkinsonism (ISO)

personality disorder (ISO)

Prenatal Exposure Delayed Effects (ISO)

pulmonary hypertension (ISO)

schizophrenia (ISO)

scrapie (ISO)

substance abuse (ISO)

substance-related disorder (ISO)

sudden infant death syndrome (ISO)

trichinosis (ISO)

withdrawal disorder (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

behavioral response to cocaine (ISO)

brain morphogenesis (IEA)

cellular response to cGMP (ISO)

cellular response to organic substance (IEA,ISO)

cellular response to retinoic acid (ISO)

circadian rhythm (ISO)

conditioned place preference (ISO)

enteric nervous system development (IEA)

membrane depolarization (ISO)

memory (ISO)

monoamine transport (IEA,ISO)

negative regulation of cerebellar granule cell precursor proliferation (ISO)

negative regulation of neuron differentiation (ISO)

negative regulation of organ growth (IEA)

negative regulation of synaptic transmission, dopaminergic (ISO)

neurotransmitter reuptake (IEA)

neurotransmitter transport (IEA)

platelet aggregation (IEA)

positive regulation of cell cycle (IEA)

positive regulation of gene expression (IEA)

positive regulation of serotonin secretion (ISO)

regulation of thalamus size (IEA,ISS)

response to estradiol (ISO)

response to hypoxia (ISO)

response to nutrient (ISO)

response to organic substance (ISO)

response to toxic substance (IEA)

response to xenobiotic stimulus (ISO)

serotonin transport (IEA,ISO)

serotonin uptake (IEA,ISO)

social behavior (IEA)

sperm ejaculation (ISO)

transmembrane transport (IEA)

vasoconstriction (ISO)

Cellular Component

anchoring junction (IEA)

cell projection (IEA)

endomembrane system (IEA)

endosome (IEA)

endosome membrane (IEA)

focal adhesion (IEA)

membrane (IEA)

membrane raft (IEA)

neuron projection (IEA)

plasma membrane (IEA)

postsynaptic membrane (ISO)

presynapse (IEA)

presynaptic membrane (ISO)

serotonergic synapse (ISO)

synapse (IEA)

Molecular Function

actin filament binding (ISO)

antiporter activity (IEA)

cocaine binding (ISO)

identical protein binding (ISO)

integrin binding (IEA)

metal ion binding (IEA)

monoamine transmembrane transporter activity (IEA)

monoatomic cation channel activity (ISO)

neurotransmitter transmembrane transporter activity (IEA)

nitric-oxide synthase binding (IEA)

protein binding (ISO)

serotonin binding (IEA)

serotonin:sodium:chloride symporter activity (IEA,ISO)

sodium ion binding (IEA)

syntaxin-1 binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

alfentanil pharmacodynamics pathway (ISO)

bupivacaine pharmacodynamics pathway (ISO)

buprenorphine pharmacodynamics pathway (ISO)

chloroprocaine pharmacodynamics pathway (ISO)

citalopram pharmacodynamics pathway (ISO)

citalopram pharmacokinetics pathway (ISO)

cocaine pharmacodynamics pathway (ISO)

codeine and morphine pharmacodynamics pathway (ISO)

desipramine pharmacodynamics pathway (ISO)

desipramine pharmacokinetics pathway (ISO)

diphenoxylate pharmacodynamics pathway (ISO)

escitalopram pharmacodynamics pathway (ISO)

ethylmorphine pharmacodynamics pathway (ISO)

fentanyl pharmacodynamics pathway (ISO)

fluoxetine pharmacodynamics pathway (ISO)

fluoxetine pharmacokinetics pathway (ISO)

heroin pharmacodynamics pathway (ISO)

hydrocodone pharmacodynamics pathway (ISO)

hydromorphone pharmacodynamics pathway (ISO)

imipramine pharmacodynamics pathway (ISO)

imipramine pharmacokinetics pathway (ISO)

levacetylmethadol pharmacodynamics pathway (ISO)

levobupivacaine phgarmacodynamics pathway (ISO)

levorphanol pharmacodynamics pathway (ISO)

lidocaine pharmacodynamics pathway (ISO)

mepivacaine pharmacodynamics pathway (ISO)

methadone pharmacodynamics pathway (ISO)

nalbuphine pharmacodynamics pathway (ISO)

naloxone pharmacodynamics pathway (ISO)

naltrexone pharmacodynamics pathway (ISO)

nicotine pharmacodynamics pathway (ISO)

oxybuprocaine pharmacodynamics pathway (ISO)

oxycodone pharmacodynamics pathway (ISO)

oxymorphone pharmacodynamics pathway (ISO)

pathogenic Escherichia coli infection pathway (ISO)

pentazocine pharmacodynamics pathway (ISO)

prilocaine pharmacodynamics pathway (ISO)

procaine pharmacodynamics pathway (ISO)

remifentanil pharmacodynamics pathway (ISO)

ropivacaine pharmacodynamics pathway (ISO)

tramadol pharmacodynamics pathway (ISO)

venlafaxine pharmacokinetics pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Slc6a4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	43,327,307 - 43,361,581 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936538	6,205,251 - 6,239,083 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936538	6,205,268 - 6,239,062 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC6A4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	30,194,319 - 30,235,697 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	30,194,319 - 30,236,002 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	28,521,337 - 28,562,715 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	25,549,032 - 25,586,841 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	25,549,031 - 25,586,831	NCBI
Celera	17	25,385,103 - 25,424,627 (-)	NCBI		Celera
Cytogenetic Map	17	q11.2	NCBI
HuRef	17	24,731,684 - 24,773,327 (-)	NCBI		HuRef
CHM1_1	17	28,583,810 - 28,625,471 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	31,138,872 - 31,180,231 (-)	NCBI		T2T-CHM13v2.0

Slc6a4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	76,889,423 - 76,923,169 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	76,889,429 - 76,923,166 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	76,998,597 - 77,032,343 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	76,998,603 - 77,032,340 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	76,812,099 - 76,845,845 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	76,814,792 - 76,848,536 (+)	NCBI		MGSCv36	mm8
Celera	11	84,497,023 - 84,530,633 (+)	NCBI		Celera
Cytogenetic Map	11	B5	NCBI
cM Map	11	46.18	NCBI

Slc6a4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	62,322,688 - 62,357,060 (+)	NCBI		GRCr8
mRatBN7.2	10	61,824,208 - 61,858,924 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	61,826,123 - 61,858,384 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	66,483,857 - 66,505,046 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	65,989,335 - 66,010,524 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	61,459,175 - 61,480,332 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	63,153,656 - 63,188,377 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	63,153,651 - 63,176,463 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	62,851,326 - 62,872,481 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	67,134,790 - 67,155,891 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	67,148,412 - 67,197,988 (-)	NCBI
Celera	10	60,845,942 - 60,866,725 (+)	NCBI		Celera
Cytogenetic Map	10	q24	NCBI

Slc6a4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955481	3,088,416 - 3,125,711 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955481	3,088,440 - 3,122,421 (+)	NCBI	ChiLan1.0	ChiLan1.0

SLC6A4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	34,227,536 - 34,255,470 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	36,108,094 - 36,136,018 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	26,546,177 - 26,572,301 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	27,050,900 - 27,089,444 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	27,050,900 - 27,092,882 (+)	Ensembl	panpan1.1		panPan2

SLC6A4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	44,224,026 - 44,259,655 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	44,224,229 - 44,259,736 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	43,375,681 - 43,398,433 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	45,040,878 - 45,077,650 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	45,042,211 - 45,077,764 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	43,823,112 - 43,845,857 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	44,109,908 - 44,132,663 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	44,194,421 - 44,217,174 (-)	NCBI		UU_Cfam_GSD_1.0

SLC6A4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	46,285,997 - 46,314,378 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	46,285,995 - 46,328,377 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	48,106,444 - 48,135,338 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC6A4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	23,929,196 - 23,969,665 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	23,927,311 - 23,955,616 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666075	6,110,560 - 6,136,546 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc6a4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624786	2,672,552 - 2,710,914 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624786	2,673,285 - 2,711,432 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021728140	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040269252	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040269253	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000662	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000004179 ⟹ ENSSTOP00000003753

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936538	6,205,251 - 6,239,083 (-)	Ensembl

RefSeq Acc Id:

XM_021728140 ⟹ XP_021583815

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	43,327,307 - 43,361,581 (-)	NCBI
SpeTri2.0	NW_004936538	6,205,268 - 6,239,062 (-)	NCBI

Sequence:

show sequence

GCTGCTCACAGGCGCAGCTGCTGCCCCGGTGCCTCGAGGGCGCGAGGGTCGCACCGCCTCCCCA
GCGCTGTACCAGCCTCCCCACGCCCAGCCGGCAGAAGAACTCTCAAACCTGCCACCATAAAGCT
CTGAGGAGATCCACAAACCCAAACAGCAAGACTCCTTCCGGTCCTTGGCAGATGGGCAGCAGCA
TTATTTACTAACCTGAAGAATGGAGACCACGCCCTTGAATTCTCAGAAGGTGCTGTCAGCCTGT
AAGGATGGAGAGGATTGTCAGAAAAATGGAGTGTTGCAGAAGGGTGTCCCCACCACAGAGGAAA
GACCCGAGTCTGGCCAAAGGTCCAATGGGTACTCTGCAGTTCCGAGCCCTAGCGCAGGAGATGA
CACTCCTAACTCTATGCCAGCTGCCACCACCACCCTAATGGCAGAGGTTCATCAGGGGGAACGG
GAGACCTGGGGCAAGAAGATGGATTTCCTCCTCTCAGTCATTGGTTATGCTGTGGACCTGGGCA
ACGTCTGGCGCTTTCCCTACATATGCTACCAGAATGGAGGAGGGGCGTTCCTTCTCCCCTACAC
CATCATGGCCATTTTCGGGGGAATTCCACTATTTTACATGGAGCTTGCACTGGGCCAGTACCAC
CGAAATGGATGCATTTCTATATGGAGGAAAATCTGCCCAATTTTCAAAGGGATCGGCTATGCCA
TCTGCATCATTGCCTTTTACATTGCCTCCTACTACAACACGATCATGGCCTGGGCACTCTACTA
CCTCATCTCCTCCTTCACGGATCAGCTGCCCTGGACCAGCTGCAAGAATTCCTGGAACACTGGC
AACTGCACCAACTATTTCTCAGAGGACAATATCACCTGGACACTCCATTCCACATCTCCTGCTG
AAGAATTTTACACGCGCCATGTCCTGCAGATCCACCGGTCTAAGGGACTCCAGGACCTGGGGGG
CATCAGCTGGCAGCTTGCCCTCTGCATCATGCTCATCTTCACCATTATCTACTTCAGCATCTGG
AAAGGTGTCAAAACTTCTGGCAAGGTGGTATGGGTGACAGCTACCTTTCCTTACATCATCCTTT
CTATCCTGCTGGTGAGGGGGGCCACCCTCCCTGGAGCCTGGAGGGGTGTCCTCTTCTACTTGAA
ACCCAACTGGCAGAAACTCCTGGAAACAGGGGTGTGGATCGATGCTGCTGCTCAGATCTTTTTC
TCTCTTGGTCCAGGCTTCGGAGTCCTCCTGGCTTTTGCTAGCTACAACAAGTTCAACAACAACT
GTTACCAAGATGCCCTGGTGACCAGTTTGGTCAACTGCATGACCAGCTTTGTTTCGGGATTTGT
CATCTTCACTGTGCTCGGGTACATGGCTGAGATGAGGAATGAAGATGTATCAGAGGTGGCCAAA
GATGCAGGACCCAGCCTCCTCTTCATCACATATGCAGAAGCCATAGCCAACATGCCTGCATCCA
CATTTTTTGCCATCATCTTCTTCCTCATGCTGATCACACTGGGCCTGGACAGCACATTTGCAGG
CTTGGAGGGTGTGATCACGGCTGTGCTAGATGAGTTTCCACACATCTGGGCCAAGCGCCGGGAG
TGGTTTGTGCTTGCTGTGGTGGTTACTTGCTTCATTGGATCCCTGGTCACCCTGACTTTTGGAG
GGGCCTATGTGGTGAAGCTGCTGGAAGAATATGCCACAGGTCCCGCGGTGCTCACCGTCGTGCT
TATAGAAGCAGTGGCTGTGTCTTGGTTCTATGGTATCACTCAGTTTTGCAGTGATGTGAAGGAA
ATGCTTGGCTTCAGCCCTGGATGGTTTTGGAGGATCTGCTGGGTAGCCATCAGCCCTATGTTTC
TCCTGTTCATCATTTGCAGTTTTTTGATGAGCCCACCCCAGCTACGACTTTTTCAATATAATTA
TCCTCACTGGAGTGTCATCCTGGGTTACTGCATAGGAACTTCATCTTTCATCTGCATCCCGACG
TATATAACTTATCGGCTGATCATCACTCCAGGGACTTTTAAGGAGCGAATTATTAAAAGTATTA
CTCCAGAAACACCAACAGAAATTCCCTGCGGGGACATCCGCTTGAATGCTGTGTAATCACTCCA
CAGAGGAAAACACTTCCCAGTTGCTGCCACCTCTAGCTCTGATGAGTCCCACCTTGCCTCTCCC
CTCCTGGTGAATTGGTTTCCAGCTGAGCCTGACAACAGAAGGGCCTTCTTCAAGGAGACACAGT
CCCAAGAGACTAAGGTGCCCAGACTCTTATGGCCTCCAGCCATTTCTTTCCATGAATCTCTGGG
ACATATTACCACGTTAGACTGTGACACAGCTGAAGTAGCCTGTTTTGGACATGTGAGGGTGTGT
ATGGAGGTGATGAGACCACCCTATCATCAGTTAGGATTAGGTTTAGCATCAAGTCTGTGAAAGT
CTACTGTATTTTTTGGGTATTATCATTGTTAGCTGATATCTGCTTCTAAGGACTCCACTGTTCA
TGAAGTCCTAACCATCTAGGAGAAAACAAAGATTGTCTTGCTAGCCGCATATTTTCTGAGTAGT
ATAGAACTCTATACCTGGAACCTTCTAGAACCCTCTAACCTATGTGCTGCTGTGGAGTCAGGAA
AAGCAGCAGCAGCTAAACTGAAAAATAATGTGTACATTTAAGTATTTGTGTGTGTGTATATTTT
TGTGTCTGTGTATTATCTCTATTCCAATACTTTGGGTCCACTACAAGCTATGAATTACCTCTAA
TTTTCTTACATTAACA

hide sequence

RefSeq Acc Id:

XM_040269252 ⟹ XP_040125186

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	43,327,307 - 43,360,974 (-)	NCBI

RefSeq Acc Id:

XM_040269253 ⟹ XP_040125187

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	43,327,307 - 43,353,529 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_021583815	(Get FASTA)	NCBI Sequence Viewer
	XP_040125186	(Get FASTA)	NCBI Sequence Viewer
	XP_040125187	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000003753.2
GenBank Protein	KAG3269683	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_021583815 ⟸ XM_021728140

- UniProtKB:

I3M3R5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

METTPLNSQKVLSACKDGEDCQKNGVLQKGVPTTEERPESGQRSNGYSAVPSPSAGDDTPNSMP
AATTTLMAEVHQGERETWGKKMDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYTIMAIFG
GIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIMAWALYYLISSFT
DQLPWTSCKNSWNTGNCTNYFSEDNITWTLHSTSPAEEFYTRHVLQIHRSKGLQDLGGISWQLA
LCIMLIFTIIYFSIWKGVKTSGKVVWVTATFPYIILSILLVRGATLPGAWRGVLFYLKPNWQKL
LETGVWIDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSLVNCMTSFVSGFVIFTVLG
YMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVIT
AVLDEFPHIWAKRREWFVLAVVVTCFIGSLVTLTFGGAYVVKLLEEYATGPAVLTVVLIEAVAV
SWFYGITQFCSDVKEMLGFSPGWFWRICWVAISPMFLLFIICSFLMSPPQLRLFQYNYPHWSVI
LGYCIGTSSFICIPTYITYRLIITPGTFKERIIKSITPETPTEIPCGDIRLNAV

hide sequence

RefSeq Acc Id:	XP_040125186 ⟸ XM_040269252
- UniProtKB:	I3M3R5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040125187 ⟸ XM_040269253
- UniProtKB:	I3M3R5 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSSTOP00000003753 ⟸ ENSSTOT00000004179

Protein Domains

Sodium:neurotransmitter symporter serotonin N-

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000004183	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000004179.3	UniProtKB/TrEMBL
InterPro	Na/ntran_symport	UniProtKB/TrEMBL
	Na/ntran_symport_serotonin_N	UniProtKB/TrEMBL
	SNS_sf	UniProtKB/TrEMBL
NCBI Gene	Slc6a4	ENTREZGENE
PANTHER	PTHR11616	UniProtKB/TrEMBL
	SODIUM-DEPENDENT SEROTONIN TRANSPORTER	UniProtKB/TrEMBL
Pfam	5HT_transport_N	UniProtKB/TrEMBL
	SNF	UniProtKB/TrEMBL
PRINTS	5HTTRANSPORT	UniProtKB/TrEMBL
	NANEUSMPORT	UniProtKB/TrEMBL
PROSITE	NA_NEUROTRAN_SYMP_1	UniProtKB/TrEMBL
	NA_NEUROTRAN_SYMP_2	UniProtKB/TrEMBL
	NA_NEUROTRAN_SYMP_3	UniProtKB/TrEMBL
Superfamily-SCOP	SSF161070	UniProtKB/TrEMBL
UniProt	I3M3R5	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB