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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:follicular lymphoma
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Accession:DOID:0050873 term browser browse the term
Definition:A B-cell lymphoma that is characterized as an indolent non-Hodgkin's lymphoma and has_material_basis_in follicle center B-cells (centrocytes and centroblasts). (DO)
Synonyms:exact_synonym: Brill Symmers Disease;   FL1;   Follicular Large Cell Lymphoma;   Follicular Lymphoma, Grade 1;   Follicular Lymphoma, Grade 2;   Follicular Lymphoma, Grade 3;   Follicular Lymphoma, Somatic;   Follicular Lymphomas;   Follicular Mixed Cell Lymphoma;   Follicular Mixed-Cell Lymphomas;   Giant Follicular Lymphoma;   Giant Follicular Lymphomas;   Large Lymphoid Lymphoma, Nodular;   Lymphocytic Lymphoma, Nodular, Poorly Differentiated;   Lymphoma, Follicular, Mixed Lymphocytic-Histiocytic;   Lymphoma, Follicular, Mixed Small and Large Lymphoid;   Lymphoma, Follicular, Small and Large Cleaved Cell;   Lymphoma, Nodular, Mixed Lymphocytic Histiocytic;   Lymphoma, Nodular, Mixed Small and Large Cell;   Lymphoma, Small Lymphoid, Follicular;   Nodular Histiocytic Lymphoma;   Nodular Histiocytic Lymphomas;   Nodular Large Follicular Center Cell Lymphoma;   Nodular Lymphoma;   Nodular Lymphomas;   follicular large-cell lymphomas;   follicular small cleaved cell lymphoma;   small follicular center cell lymphoma
 narrow_synonym: Cutaneous Follicular Lymphoma
 related_synonym: FOLLICULAR LYMPHOMA, SUSCEPTIBILITY TO, 1
 primary_id: MESH:D008224
 alt_id: OMIM:613024
 xref: EFO:1000211;   GARD:2356;   ICDO:9690/3;   MONDO:0018906;   NCI:C3209;   NCI:C3465

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follicular lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap1 ATPase H+ transporting accessory protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26691987 NCBI chrNW_004955580:927,546...934,633
Ensembl chrNW_004955580:927,114...934,734 		JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26691987 NCBI chrNW_004955403:43,860,811...43,886,398
Ensembl chrNW_004955403:43,860,728...43,886,732 		JBrowse link
G Bcl10 BCL10 immune signaling adaptor ISO ClinVar Annotator: match by term: Follicular lymphoma ClinVar PMID:9989495 NCBI chrNW_004955423:8,710,231...8,720,530
Ensembl chrNW_004955423:8,709,890...8,722,050 		JBrowse link
G Bcl2 BCL2 apoptosis regulator susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:translocation: ;t(14;18)(q32;q21)		 RGD
CTD		 PMID:3287162 PMID:12855623 PMID:16671111 RGD:1599473 RGD:734639 NCBI chrNW_004955402:46,911,125...47,084,214
Ensembl chrNW_004955402:46,916,266...47,084,485 		JBrowse link
G Cd40 CD40 molecule susceptibility ISO DNA:SNP:5' utr:c.-1C>T (rs1883832) (human) RGD PMID:20473910 RGD:5490541 NCBI chrNW_004955445:11,191,817...11,202,156
Ensembl chrNW_004955445:11,190,603...11,202,093 		JBrowse link
G Cd40lg CD40 ligand ISO human gene in a mouse model RGD PMID:25582824 RGD:11344981 NCBI chrNW_004955489:8,465,571...8,477,714
Ensembl chrNW_004955489:8,465,164...8,477,746 		JBrowse link
G Cd79b CD79b molecule treatment ISO human cells in mouse model RGD PMID:17374736 RGD:151665154 NCBI chrNW_004955478:7,909,353...7,912,814
Ensembl chrNW_004955478:7,909,153...7,913,166 		JBrowse link
G Crebbp CREB binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:24362818 NCBI chrNW_004955442:13,559,496...13,691,913
Ensembl chrNW_004955442:13,559,496...13,692,004 		JBrowse link
G Ebf1 EBF transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24362818 NCBI chrNW_004955408:12,735,893...13,121,700
Ensembl chrNW_004955408:12,739,083...13,121,699 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:24362818 NCBI chrNW_004955491:4,215,353...4,292,229
Ensembl chrNW_004955491:4,215,298...4,292,235 		JBrowse link
G Irf4 interferon regulatory factor 4 severity ISO RGD PMID:17296585 RGD:11530032 NCBI chrNW_004955465:12,497,534...12,512,529
Ensembl chrNW_004955465:12,497,462...12,513,106 		JBrowse link
G Kdsr 3-ketodihydrosphingosine reductase ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:8417785 PMID:25526675 RGD:1598985 NCBI chrNW_004955402:47,092,779...47,130,131
Ensembl chrNW_004955402:47,092,779...47,130,132 		JBrowse link
G Kmt2d lysine methyltransferase 2D ISO CTD Direct Evidence: marker/mechanism CTD PMID:24362818 NCBI chrNW_004955500:7,850,782...7,891,703
Ensembl chrNW_004955500:7,853,292...7,886,067 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16410450 NCBI chrNW_004955486:2,096,379...2,112,240
Ensembl chrNW_004955486:2,096,379...2,112,240 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16410450 NCBI chrNW_004955492:3,372,915...3,474,173
Ensembl chrNW_004955492:3,376,512...3,474,180 		JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:24362818 NCBI chrNW_004955427:25,553,589...25,557,654
Ensembl chrNW_004955427:25,553,589...25,559,138 		JBrowse link
G Rarres1 retinoic acid receptor responder 1 ISO OMIM:151430 MouseDO NCBI chrNW_004955448:9,437,365...9,466,565
Ensembl chrNW_004955448:9,437,859...9,450,380 		JBrowse link
G Rragc Ras related GTP binding C ISO CTD Direct Evidence: marker/mechanism CTD PMID:26691987 NCBI chrNW_004955452:16,469,426...16,486,336
Ensembl chrNW_004955452:16,466,453...16,486,336 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24362818 NCBI chrNW_004955436:21,566,591...21,581,551
Ensembl chrNW_004955436:21,566,423...21,578,469 		JBrowse link
G Tyms thymidylate synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16410450 NCBI chrNW_004955402:9,295,862...9,304,952
Ensembl chrNW_004955402:9,296,321...9,306,631 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16063
    disease of cellular proliferation 6683
      Neoplasms by Histologic Type 4641
        lymphoma 500
          non-Hodgkin lymphoma 423
            follicular lymphoma 20
Path 2
Term Annotations click to browse term
  disease 16063
    disease of cellular proliferation 6683
      cancer 4847
        organ system cancer 4630
          immune system cancer 587
            lymphatic system cancer 587
              lymphoma 500
                non-Hodgkin lymphoma 423
                  B-cell lymphoma 310
                    follicular lymphoma 20
paths to the root