Mtr (5-methyltetrahydrofolate-homocysteine methyltransferase) - Rat Genome Database

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Gene: Mtr (5-methyltetrahydrofolate-homocysteine methyltransferase) Chinchilla lanigera
Analyze
Symbol: Mtr
Name: 5-methyltetrahydrofolate-homocysteine methyltransferase
RGD ID: 8961365
Description: ENCODES a protein that exhibits amino acid binding (ortholog); folic acid binding (ortholog); methionine synthase activity (ortholog); INVOLVED IN axon regeneration (ortholog); cellular response to methionine (ortholog); cellular response to nitric oxide (ortholog); PARTICIPATES IN altered folate cycle metabolic pathway; altered folate mediated one-carbon metabolic pathway; choline metabolic pathway; ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); autistic disorder (ortholog); Breast Neoplasms (ortholog); FOUND IN cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: methionine synthase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554923,376,512 - 3,474,180 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554923,372,915 - 3,474,173 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (ISO)

Molecular Function

References


Genomics

Comparative Map Data
Mtr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554923,376,512 - 3,474,180 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554923,372,915 - 3,474,173 (-)NCBIChiLan1.0ChiLan1.0
MTR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381236,795,281 - 236,903,981 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1236,795,260 - 236,921,278 (+)EnsemblGRCh38hg38GRCh38
GRCh371236,958,581 - 237,067,281 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361235,025,341 - 235,130,585 (+)NCBINCBI36hg18NCBI36
Build 341233,284,758 - 233,390,001NCBI
Celera1210,207,757 - 210,316,611 (+)NCBI
Cytogenetic Map1q43NCBI
HuRef1207,414,687 - 207,523,271 (+)NCBIHuRef
CHM1_11238,230,032 - 238,338,720 (+)NCBICHM1_1
Mtr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391312,196,217 - 12,273,090 (-)NCBIGRCm39mm39
GRCm39 Ensembl1312,197,598 - 12,272,999 (-)Ensembl
GRCm381312,181,331 - 12,258,199 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1312,182,712 - 12,258,113 (-)EnsemblGRCm38mm10GRCm38
MGSCv371312,279,086 - 12,350,267 (-)NCBIGRCm37mm9NCBIm37
MGSCv361312,240,869 - 12,312,428 (-)NCBImm8
Celera1312,106,428 - 12,177,671 (-)NCBICelera
Cytogenetic Map13A1NCBI
cM Map134.52NCBI
Mtr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21758,219,998 - 58,308,560 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1758,220,071 - 58,304,822 (+)Ensembl
Rnor_6.01766,210,444 - 66,295,014 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1766,210,461 - 66,295,014 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01767,954,893 - 68,041,488 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41768,782,708 - 68,867,101 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11768,793,540 - 68,877,930 (+)NCBI
Celera1762,230,512 - 62,313,601 (-)NCBICelera
Cytogenetic Map17q12.1NCBI
MTR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11217,352,707 - 217,461,313 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1217,358,050 - 217,460,946 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01212,353,195 - 212,463,304 (+)NCBIMhudiblu_PPA_v0panPan3
MTR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.143,219,851 - 3,328,000 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl43,215,090 - 3,328,115 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha43,267,770 - 3,375,365 (-)NCBI
ROS_Cfam_1.043,240,178 - 3,347,933 (-)NCBI
ROS_Cfam_1.0 Ensembl43,243,029 - 3,347,943 (-)Ensembl
UMICH_Zoey_3.143,239,421 - 3,346,967 (-)NCBI
UNSW_CanFamBas_1.043,370,826 - 3,478,490 (-)NCBI
UU_Cfam_GSD_1.043,591,890 - 3,699,525 (-)NCBI
Mtr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934439,925,911 - 40,014,880 (-)NCBI
SpeTri2.0NW_00493648416,087,924 - 16,180,089 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MTR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1454,546,981 - 54,652,759 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11454,546,978 - 54,652,780 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21458,497,706 - 58,627,105 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MTR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12573,935,666 - 74,039,872 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2573,935,225 - 74,038,741 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605576,034,340 - 76,141,359 (+)NCBIVero_WHO_p1.0
Mtr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477513,791,690 - 13,903,888 (-)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000024456   ⟹   ENSCLAP00000024222
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554923,376,512 - 3,474,180 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000024457   ⟹   ENSCLAP00000024223
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554923,376,512 - 3,474,180 (-)Ensembl
RefSeq Acc Id: XM_005404926   ⟹   XP_005404983
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554923,372,915 - 3,474,173 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005404927   ⟹   XP_005404984
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554923,372,915 - 3,474,173 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005404983 (Get FASTA)   NCBI Sequence Viewer  
  XP_005404984 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005404983   ⟸   XM_005404926
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005404984   ⟸   XM_005404927
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCLAP00000024223   ⟸   ENSCLAT00000024457
RefSeq Acc Id: ENSCLAP00000024222   ⟸   ENSCLAT00000024456


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000016630 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCLAP00000024222 ENTREZGENE, UniProtKB/TrEMBL
  ENSCLAP00000024223 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000024456 ENTREZGENE, UniProtKB/TrEMBL
  ENSCLAT00000024457 ENTREZGENE, UniProtKB/TrEMBL
NCBI Gene Mtr ENTREZGENE
UniProt A0A8C2W357_CHILA UniProtKB/TrEMBL
  A0A8C2YUH6_CHILA UniProtKB/TrEMBL