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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:allergic asthma
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Accession:DOID:9415 term browser browse the term
Definition:An extrinsic asthma that is characterized by symptoms that are triggered by an allergic reaction caused by inhaled allergens such as dust mite allergen, pet dander, pollen and mold. The disease has_symptom coughing, has_symptom wheezing, has_symptom shortness of breath or has_symptom rapid breathing, and has_symptom chest tightness. (DO)
Synonyms:exact_synonym: allergic atopic asthma;   extrinsic asthma with acute exacerbation;   extrinsic asthma with status asthmaticus
 related_synonym: atopic asthma
 xref: EFO:0010638;   ICD10CM:J45;   ICD9CM:493.0



show annotations for term's descendants           Sort by:
allergic asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL26 C-C motif chemokine ligand 26 treatment ISO RGD PMID:25530546 RGD:11081163 NCBI chr 6:7,151,352...7,154,509
Ensembl chr 6:7,151,212...7,154,726
JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 treatment ISO RGD PMID:23933317 RGD:40903070 NCBI chr  X:60,462,290...60,513,155
Ensembl chr  X:60,463,526...60,464,548
JBrowse link
G DLA-DRB1 MHC class II DLA DRB1 beta chain susceptibility ISO RGD PMID:22397267 RGD:13506905 NCBI chr12:2,151,409...2,164,564 JBrowse link
G DLA88 MHC class I DLA-88 susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr12:892,442...895,691
Ensembl chr12:892,388...1,021,690
JBrowse link
G EPX eosinophil peroxidase ISO protein:increased expression:urine: RGD PMID:11846868 RGD:13506893 NCBI chr 9:32,855,568...32,865,445
Ensembl chr 9:32,855,507...32,865,022
JBrowse link
G IL25 interleukin 25 treatment ISO RGD PMID:17889290 RGD:40902975 NCBI chr 8:3,621,268...3,624,689
Ensembl chr 8:3,618,161...3,624,043
JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 exacerbates ISO RGD PMID:21592044 RGD:126928124 NCBI chr12:9,990,678...10,000,195
Ensembl chr12:9,990,679...10,000,236
JBrowse link
Experimental Allergic Asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL3 acyl-CoA synthetase long chain family member 3 ISO RGD PMID:23526225 RGD:13831300 NCBI chr37:28,882,264...28,929,451
Ensembl chr37:28,864,147...28,938,866
JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658
JBrowse link
G CD86 CD86 molecule treatment ISO RGD PMID:25344652 RGD:11354965 NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087
JBrowse link
G FAS Fas cell surface death receptor treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321
JBrowse link
G FASLG Fas ligand treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chr 7:26,335,837...26,344,224
Ensembl chr 7:26,335,846...26,344,224
JBrowse link
G IL23A interleukin 23 subunit alpha ISO RGD PMID:19935773 PMID:26344076 RGD:11251537 RGD:5037240 NCBI chr10:635,384...640,715
Ensembl chr10:638,719...640,359
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15728
    disease of anatomical entity 15372
      respiratory system disease 4968
        respiratory allergy 369
          allergic asthma 13
            Experimental Allergic Asthma 6
            cobalt allergic asthma 0
            hexahydrophthalic anhydride allergic asthma 0
            isocyanates allergic asthma + 0
            maleic anhydride allergic asthma 0
            meropenem allergy 0
            nickel allergic asthma 0
            phthalic anhydride allergic asthma 0
            tetrachlorophthalic anhydride allergic asthma 0
            thunderstorm triggered asthma 0
            trimellitic anhydride allergic asthma 0
Path 2
Term Annotations click to browse term
  disease 15728
    disease of anatomical entity 15372
      Immune & Inflammatory Diseases 5204
        immune system disease 4611
          allergic disease 583
            Immediate Hypersensitivity 445
              respiratory allergy 369
                asthma 333
                  chronic asthma 47
                    extrinsic asthma 13
                      allergic asthma 13
                        Experimental Allergic Asthma 6
                        cobalt allergic asthma 0
                        hexahydrophthalic anhydride allergic asthma 0
                        isocyanates allergic asthma + 0
                        maleic anhydride allergic asthma 0
                        meropenem allergy 0
                        nickel allergic asthma 0
                        phthalic anhydride allergic asthma 0
                        tetrachlorophthalic anhydride allergic asthma 0
                        thunderstorm triggered asthma 0
                        trimellitic anhydride allergic asthma 0
paths to the root