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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Immediate Hypersensitivity
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Accession:DOID:9002850 term browser browse the term
Definition:Hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability.
Synonyms:exact_synonym: Atopic Hypersensitivities;   Atopic Hypersensitivity;   IgE Mediated Hypersensitivity;   IgE-Mediated Hypersensitivities;   Immediate Hypersensitivities;   Type I Hypersensitivities;   Type I Hypersensitivity
 primary_id: MESH:D006969
 alt_id: RDO:0001896
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
 
Immediate Hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 ISO DNA:SNPs: :multiple (human) RGD PMID:16387594 RGD:5129207 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arg2 arginase 2 ISO DNA:SNP (human) RGD PMID:16387594 RGD:5129207 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 IEP mRNA:increased expression:nasal cavity epithelium RGD PMID:15823807 RGD:2307177 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEP mRNA:increased expression:nasal cavity epithelium RGD PMID:15823807 RGD:2307177 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) IMP RGD PMID:9918599 RGD:2316235 NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654
JBrowse link
G Egfr epidermal growth factor receptor ISO DNA:snps:multiple (human) RGD PMID:20357714 RGD:5131868 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 ISO RGD PMID:19188657 RGD:5131872 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Fcer2 Fc epsilon receptor II ISO CTD Direct Evidence: marker/mechanism CTD PMID:22967010 NCBI chr12:1,742,809...1,754,476
Ensembl chr12:1,742,815...1,754,476
JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il13 interleukin 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 PMID:22967010 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il18 interleukin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22967010 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il33 interleukin 33 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22967010 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Il4 interleukin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12755381 PMID:20485159 PMID:22967010 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il4r interleukin 4 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
JBrowse link
G Ms4a2 membrane spanning 4-domains A2 susceptibility ISO Atopy and bronchial hyperresponsiveness, OMIM:147050
Atopy and bronchial hyperresponsiveness, OMIM:147050 DNA:polymorphism:CDS:amino acid E237G
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:8817330 PMID:20485159 PMID:8817330 RGD:1599903, RGD:1599903 NCBI chr 1:208,440,179...208,448,716
Ensembl chr 1:208,440,361...208,448,310
JBrowse link
G Pla2g7 phospholipase A2 group VII ISO CTD Direct Evidence: marker/mechanism CTD PMID:10733466 NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476
JBrowse link
G Selp selectin P ISO atopy and bronchial hyperresponsiveness, OMIM:147050 RGD PMID:12929084 RGD:1599904 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845
JBrowse link
acquired angioedema term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F12 coagulation factor XII disease_progression ISO RGD PMID:9129025 RGD:11565081 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
JBrowse link
G F2 coagulation factor II disease_progression ISO protein:increased expression:plasma: RGD PMID:9129025 RGD:11565081 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F7 coagulation factor VII disease_progression ISO RGD PMID:9129025 RGD:11565081 NCBI chr16:76,489,779...76,500,636
Ensembl chr16:76,489,717...76,500,610
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase ISO ClinVar Annotator: match by term: Susceptibility to angioedema induced by ACE inhibitors ClinVar PMID:1551674 PMID:1972698 PMID:1978554 PMID:1978555 PMID:2503817 More... NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Kng2 kininogen 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9734886 NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971
JBrowse link
G Serping1 serpin family G member 1 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:9734886 PMID:23406939 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034
JBrowse link
G Xpnpep2 X-prolyl aminopeptidase 2 susceptibility ISO ClinVar Annotator: match by term: Susceptibility to angioedema induced by ACE inhibitors
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:16175507 PMID:20625347 PMID:21898657 NCBI chr  X:127,287,765...127,317,036
Ensembl chr  X:127,287,979...127,317,223
JBrowse link
allergic asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl26 C-C motif chemokine ligand 26 treatment ISO RGD PMID:25530546 RGD:11081163 NCBI chr12:21,109,384...21,114,336
Ensembl chr12:21,109,421...21,114,335
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 treatment ISO RGD PMID:23933317 RGD:40903070 NCBI chr  X:71,661,415...71,690,158
Ensembl chr  X:71,663,821...71,690,121
JBrowse link
G Epx eosinophil peroxidase ISO protein:increased expression:urine: RGD PMID:11846868 RGD:13506893 NCBI chr10:72,666,865...72,677,952
Ensembl chr10:72,666,865...72,677,952
JBrowse link
G Il25 interleukin 25 treatment ISO RGD PMID:17889290 RGD:40902975 NCBI chr15:28,408,842...28,411,676
Ensembl chr15:28,408,842...28,411,893
JBrowse link
G RT1-A1 RT1 class Ia, locus A1 susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr20:4,905,309...4,914,593 JBrowse link
G RT1-B RT1 class II, locus B susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910
G RT1-Db1 RT1 class II, locus Db1 susceptibility ISO RGD PMID:22397267 RGD:13506905 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G RT1-Ha RT1 class II, locus Ha susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr20:4,760,631...4,770,662
Ensembl chr20:4,760,118...4,770,244
JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 exacerbates ISO RGD PMID:21592044 PMID:21592044 RGD:126928124, RGD:126928124 NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203
JBrowse link
allergic bronchopulmonary aspergillosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl17 C-C motif chemokine ligand 17 ISO associated with Cystic Fibrosis RGD PMID:17898016 RGD:4145612 NCBI chr19:10,202,317...10,203,768
Ensembl chr19:10,202,128...10,203,819
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ISO RGD PMID:15951834 RGD:5688155 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO RGD PMID:10946288 RGD:8661731 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Cftr CF transmembrane conductance regulator ISO DNA:mutations: : RGD PMID:11243954 RGD:4140482 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO RGD PMID:7743671 RGD:8547590 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il1a interleukin 1 alpha ISO RGD PMID:8699818 RGD:7794730 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO Chronic Necrotizing Pulmonary Aspergillosis; DNA:missense mutation:exon:p.R52C (human)
DNA:SNP:intron:1011G>A(human)
RGD PMID:11474427 PMID:16487239 RGD:4889577, RGD:8693711 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G RT1-Bb RT1 class II, locus Bb susceptibility ISO associated with cystic fibrosis; DNA:polymorphisms: :DQB1*06:02, DQB1*02:01(human) RGD PMID:23278646 RGD:36049760 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 susceptibility ISO associated with cystic fibrosis; DNA:polymorphisms: : RGD PMID:23278646 RGD:36049760 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G Tlr9 toll-like receptor 9 susceptibility ISO DNA:SNP:promoter:g.-1237T>C rs5743836 (human) RGD PMID:18275280 PMID:18936185 RGD:5130863, RGD:5130858 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
JBrowse link
G Tnf tumor necrosis factor ISO RGD PMID:8699818 RGD:7794730 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A susceptibility ISO DNA:snps:5' utr, exon:g.-609G>T rs4149570, g.36A>G rs767455 (human) RGD PMID:20646338 RGD:5131174 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
allergic conjunctivitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl11 C-C motif chemokine ligand 11 IEP mRNA:increased expression:conjunctiva RGD PMID:12682842 RGD:2307196 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ISO RGD PMID:19553621 RGD:8548840 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEP mRNA:increased expression:conjunctiva RGD PMID:12682842 RGD:2307196 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 ISO protein:increased expression:conjunctiva RGD PMID:11090473 RGD:6483824 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO RGD PMID:18658092 RGD:6893389 NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO RGD PMID:8766745 RGD:8547686 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifng interferon gamma IDA
ISO
RGD PMID:12234900 PMID:16123425 RGD:8142386, RGD:8142391 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il10 interleukin 10 treatment ISO protein:increased expression:tear RGD PMID:22092652 PMID:16914468 PMID:15144463 PMID:19060266 RGD:7364837, RGD:11041889, RGD:7365076, RGD:7365027 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il13 interleukin 13 ISO associated with Allergic Rhinitis;DNA:SNPs, haplotype:promoter, exon:-1112C>T (rs1800925), p.R130Q (rs20541) (human) RGD PMID:9191598 PMID:22023794 RGD:8549533, RGD:8549595 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il1b interleukin 1 beta treatment ISO RGD PMID:9326725 RGD:7401198 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO human protein in a mouse model RGD PMID:10549671 RGD:8549802 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il4r interleukin 4 receptor susceptibility ISO associated with rhinitis; DNA:SNP: : rs2107356 (human) RGD PMID:20002627 RGD:4890389 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
JBrowse link
G Irf1 interferon regulatory factor 1 IEP RGD PMID:14605445 RGD:5128787 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase IDA protein:increased phosphorylation:T cell RGD PMID:14507881 RGD:1600225 NCBI chr 5:141,888,319...141,916,992
Ensembl chr 5:141,888,326...141,903,794
JBrowse link
G Muc1 mucin 1, cell surface associated severity ISO RGD PMID:17177679 RGD:7349351 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming severity ISO RGD PMID:17177679 RGD:7349351 NCBI chr 1:196,796,257...196,831,740
Ensembl chr 1:196,799,517...196,831,756
JBrowse link
G Muc4 mucin 4, cell surface associated severity ISO RGD PMID:17177679 PMID:11581187 RGD:7349351, RGD:7349400 NCBI chr11:68,008,245...68,053,229 JBrowse link
G Pla2g2a phospholipase A2 group IIA ISO protein:increased expression:body fluid or substance RGD PMID:21042565 RGD:6482725 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
JBrowse link
G Tgfb1 transforming growth factor, beta 1 treatment ISO RGD PMID:16914468 RGD:11041889 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tlr2 toll-like receptor 2 ISO associated with Staphylococcal Infections; RGD PMID:19358332 RGD:8552826 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tlr4 toll-like receptor 4 ISO mRNA,protein:increased expression:conjunctiva: RGD PMID:21820713 PMID:16023216 PMID:21391988 RGD:7777131, RGD:7794849, RGD:7794770 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr9 toll-like receptor 9 ISO mRNA,protein:decreased expression:conjunctiva: RGD PMID:16023216 RGD:7794849 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
JBrowse link
G Tnc tenascin C ISO DNA:SNPs: :multiple (human) RGD PMID:18305139 RGD:4889589 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
JBrowse link
allergic rhinitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A severity ISO DNA:snp:exon:c.1236C>T (human) RGD PMID:24040855 RGD:8657076 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Ace angiotensin I converting enzyme no_association ISO DNA:deletion:intron:IVS16+1464-1751del (human) RGD PMID:15112973 RGD:8142345 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Bcl2 BCL2, apoptosis regulator IEP mRNA, protein:increased expression:nasal mucosa (rat) RGD PMID:15362690 RGD:11522724 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:29028686 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 treatment IDA RGD PMID:23089405 RGD:7248414 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccl26 C-C motif chemokine ligand 26 ISO protein:increased expression:oronasal secretion (human) RGD PMID:23883806 RGD:7364793 NCBI chr12:21,109,384...21,114,336
Ensembl chr12:21,109,421...21,114,335
JBrowse link
G Cd40 CD40 molecule ISO protein:increased expression:lymphocyte RGD PMID:19086656 RGD:8547782 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd40lg CD40 ligand ISO protein:increased expression:lymphocyte RGD PMID:19086656 RGD:8547782 NCBI chr  X:135,127,119...135,138,302
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 treatment ISO RGD PMID:10436391 RGD:11344920 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
JBrowse link
G F2 coagulation factor II ISO protein:increased expression:nasal mucus RGD PMID:21711961 RGD:5147783 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G Fcgr3a Fc gamma receptor 3A susceptibility ISO DNA:polymorphism:exon:p.F158V(rs396991)(human) RGD PMID:18199088 RGD:5508449 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921
JBrowse link
G Hrh1 histamine receptor H 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23333628 NCBI chr 4:147,564,781...147,649,353
Ensembl chr 4:147,645,995...147,647,455
JBrowse link
G Ifng interferon gamma treatment ISO
IDA
associated with Asthma RGD PMID:12787306 PMID:18510219 RGD:7829803, RGD:10755770 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il10 interleukin 10 treatment ISO RGD PMID:23883806 PMID:23253209 RGD:7364793, RGD:7364818 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il13 interleukin 13 susceptibility
no_association
ISO DNA:polymorphism:exon:c. 2044G>A (human)
ClinVar Annotator: match by term: Allergic rhinitis
CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds:p.R130Q (rs20541) (human)
DNA:SNPs:promoter, cds:-1112C>T, p.R130Q (rs1800925, rs20541) (human)
DNA:SNP:promoter:-1512A>C (rs1881457) (human)
ClinVar
CTD
OMIM
RGD
PMID:10699178 PMID:12928861 PMID:15356556 PMID:15483090 PMID:15711639 More... RGD:4152796, RGD:8549518, RGD:8549516, RGD:8549501 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 ISO protein:increased expression:serum RGD PMID:21462799 RGD:8549521 NCBI chr  X:111,002,590...111,074,053
Ensembl chr  X:111,002,592...111,072,381
JBrowse link
G Il17a interleukin 17A susceptibility ISO DNA:snp:promoter:c.-444A>G (human)
mRNA:increased expression:peripheral blood mononuclear cell (human)
RGD PMID:22507625 PMID:21535180 RGD:9068429, RGD:5147409 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il18 interleukin 18 severity
no_association
ISO DNA:SNP:promoter:-137G>C (rs187238) (human)
DNA:SNP:promoter:-140C>G (rs360721) (human)
RGD PMID:22840759 PMID:22840759 RGD:8655914, RGD:8655914 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1b interleukin 1 beta ISO protein:increased expression:nasal mucus RGD PMID:7750009 RGD:7401199 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 IEP RGD PMID:12592663 RGD:8662963 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4 interleukin 4 treatment ISO
IEP
RGD PMID:9893928 PMID:24620662 PMID:8908280 PMID:14653048 RGD:7829796, RGD:11522769, RGD:7829827, RGD:7829802 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5 interleukin 5 treatment IEP RGD PMID:23934070 PMID:24620662 RGD:11354976, RGD:11522769 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Itgb2 integrin subunit beta 2 treatment IEP RGD PMID:12046991 RGD:9698435 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
JBrowse link
G Muc1 mucin 1, cell surface associated severity ISO
IMP
IEP
mRNA,protein:decreased expression:nasal mucosa RGD PMID:31425778 PMID:31425778 PMID:31425778 RGD:127345100, RGD:127345100, RGD:127345100 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Muc1em1Cgen mucin 1, cell surface associated; TALEN induced mutant 1, Cgen severity IMP RGD PMID:31425778 RGD:127345100
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming IEP mRNA, protein:increased expression:nasal cavity epithelium RGD PMID:22972875 RGD:7364746 NCBI chr 1:196,864,375...196,896,475
Ensembl chr 1:196,864,336...196,896,475
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO mRNA:increased expression:nasal mucosa (human) RGD PMID:23858718 RGD:8547523 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G Pon1 paraoxonase 1 severity ISO protein:decreased activity:plasma (human) RGD PMID:23406590 RGD:8547583 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IEP protein:increased expression:nasal cavity epithelium RGD PMID:24012634 RGD:7775060 NCBI chr 1:228,409,883...229,638,794
Ensembl chr 1:228,408,947...229,639,080
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16979129 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 ISO RGD PMID:20487636 RGD:5144132 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 ISO mRNA:decreased expression:nasal mucosa, lung RGD PMID:17882576 RGD:5144135 NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610
JBrowse link
G Scgb3a2 secretoglobin, family 3A, member 2 susceptibility ISO DNA:SNP: :rs7726552 (human) RGD PMID:21410962 RGD:5144225 NCBI chr18:35,932,840...35,935,762
Ensembl chr18:35,932,840...35,935,762
JBrowse link
G Serpine1 serpin family E member 1 ISO mRNA:increased expression:nasal mucosa (mouse) RGD PMID:21339035 RGD:8547809 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Tacr1 tachykinin receptor 1 IEP mRNA:increased expression:nasal mucosa RGD PMID:12768696 RGD:5147835 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733
JBrowse link
G Tgfb1 transforming growth factor, beta 1 treatment IEP RGD PMID:31368266 RGD:14995445 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tlr2 toll-like receptor 2 severity ISO DNA:polymorphism:cds:p.R753Q(human)
protein:increased expression:neutrophil:
mRNA:decreased expression:nasal mucosa:
RGD PMID:22402138 PMID:22555057 PMID:18381801 PMID:18219831 RGD:7800732, RGD:8552993, RGD:8552972, RGD:7800742 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tlr4 toll-like receptor 4 severity
treatment
susceptibility
no_association
ISO DNA:polymorphism:cds:p.D299G(human)
protein:increased expression:nasal lavage,leukocyte, bone marrow:
protein:decreased expression:nasal mucosa:
DNA:SNP: :rs1927911(human)
DNA:polymorphism: :4216G>C(human)
RGD PMID:22402138 PMID:22555057 PMID:22577387 PMID:17069098 PMID:23639307 More... RGD:7800732, RGD:8552993, RGD:7800740, RGD:7800738, RGD:7800736, RGD:4145354 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr9 toll-like receptor 9 ISO protein:decreased expression:nasal mucosa: RGD PMID:22577387 RGD:7800740 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
JBrowse link
Allergic Rhinoconjunctivitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 treatment ISO associated with Eosinophilic Esophagitis; DNA:polymorphisms:: RGD PMID:26416193 RGD:11352743 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Il3 interleukin 3 susceptibility ISO DNA:SNP: :rs40401(human) RGD PMID:23953855 RGD:13506915 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
JBrowse link
Anaphylaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 disease_progression IMP RGD PMID:20959119 RGD:6893644 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Agt angiotensinogen ISO RGD PMID:1422942 RGD:8548893 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Aspg asparaginase ISO CTD Direct Evidence: marker/mechanism CTD PMID:65671 NCBI chr 6:131,176,727...131,196,268
Ensembl chr 6:131,176,874...131,196,268
JBrowse link
G Btk Bruton tyrosine kinase treatment IMP RGD PMID:22228807 RGD:11040701 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853
JBrowse link
G Cabs1 calcium binding protein, spermatid associated 1 treatment ISO RGD PMID:25632019 RGD:14400306 NCBI chr14:20,096,962...20,099,024
Ensembl chr14:20,096,899...20,099,181
JBrowse link
G Cma1 chymase 1 ISO protein:increased expression:lung, mast cell (human) RGD PMID:17081716 RGD:5128820 NCBI chr15:29,417,451...29,420,233
Ensembl chr15:29,417,451...29,420,233
JBrowse link
G Fcgr2a Fc gamma receptor 2A susceptibility ISO associated with Agammaglobulinemia;DNA:mutation:splice junction: RGD PMID:23545275 PMID:26396093 RGD:11040993, RGD:11040995 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
JBrowse link
G Grap2 GRB2-related adaptor protein 2 ameliorates ISO RGD PMID:18664516 RGD:126790488 NCBI chr 7:112,117,142...112,190,880
Ensembl chr 7:112,117,142...112,190,877
JBrowse link
G Hdac3 histone deacetylase 3 ISO RGD PMID:24619412 RGD:9590165 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856
JBrowse link
G Hp haptoglobin ISO RGD PMID:12147031 RGD:11041789 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
JBrowse link
G Il4 interleukin 4 ISO mRNA:increased expression:lung, intestine, spleen
associated with cystic echinococcosis; protein:increased expression:blood
RGD PMID:24468678 PMID:28095662 RGD:10402796, RGD:14696684 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Kng2 kininogen 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7623993 NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971
JBrowse link
G Ltb4r leukotriene B4 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:10934231 NCBI chr15:29,263,126...29,265,716 JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19767079 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 IMP RGD PMID:18480553 RGD:2300247 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP
ISO
RGD PMID:18480553 PMID:17822719 RGD:2300247, RGD:1642600 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 IMP RGD PMID:21604443 RGD:7207802 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Wfdc6a WAP four-disulfide core domain 6A ISO CTD Direct Evidence: marker/mechanism CTD PMID:20693069 NCBI chr 3:153,305,336...153,309,144
Ensembl chr 3:153,305,336...153,309,144
JBrowse link
angioedema term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:8458210 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G F12 coagulation factor XII ISO DNA:missense:exon:T309K,T309R
ClinVar Annotator: match by term: Angioedema
ClinVar
RGD
PMID:16638441 PMID:25741868 PMID:16638441 RGD:1601106 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: marker/mechanism CTD PMID:16184341 PMID:18453163 PMID:20547619 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G RT1-Bb RT1 class II, locus Bb ISO CTD Direct Evidence: marker/mechanism CTD PMID:15784113 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15784113 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G Serping1 serpin family G member 1 susceptibility ISO DNA:mutations:exon
ClinVar Annotator: match by term: Angioedema
ClinVar
RGD
PMID:12402344 RGD:1600545 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034
JBrowse link
G Slc34a1 solute carrier family 34 member 1 ISO ClinVar Annotator: match by term: Angioedema ClinVar PMID:16638441 PMID:25741868 NCBI chr17:9,218,876...9,233,852
Ensembl chr17:9,218,876...9,233,852
JBrowse link
G Sytl2 synaptotagmin-like 2 ISO ClinVar Annotator: match by term: Angioedema ClinVar PMID:28327206 NCBI chr 1:144,272,870...144,379,310
Ensembl chr 1:144,273,360...144,379,222
JBrowse link
G Xpnpep2 X-prolyl aminopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16175507 NCBI chr  X:127,287,765...127,317,036
Ensembl chr  X:127,287,979...127,317,223
JBrowse link
aspirin-induced respiratory disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacng6 calcium voltage-gated channel auxiliary subunit gamma 6 susceptibility ISO DNA:SNP,haplotype:rs192808(human) RGD PMID:20860846 RGD:13524562 NCBI chr 1:65,732,910...65,747,377
Ensembl chr 1:65,732,632...65,747,341
JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20485159 PMID:20022477 RGD:4145619 NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 PMID:17641958 PMID:20485159 NCBI chr  X:71,661,415...71,690,158
Ensembl chr  X:71,663,821...71,690,121
JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 ISO DNA:SNPs: :-819T>G, 2078C>T, 2534A>G (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16502481 PMID:20485159 PMID:15970796 RGD:5144000 NCBI chr15:48,190,251...48,229,906
Ensembl chr15:48,189,073...48,304,136
JBrowse link
G Fancc FA complementation group C ISO DNA:haplotype::rs4647416(human) RGD PMID:21670957 RGD:11045795 NCBI chr17:1,680,660...1,822,610
Ensembl chr17:1,681,324...1,829,376
JBrowse link
G Il4 interleukin 4 susceptibility ISO DNA:SNPs:promoter,5'UTR,intron:multiple RGD PMID:20921925 RGD:11528633 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Ltc4s leukotriene C4 synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:9393345 PMID:9466979 PMID:10970818 PMID:20485159 NCBI chr10:34,560,476...34,562,790
Ensembl chr10:34,560,360...34,562,651
JBrowse link
G Ms4a2 membrane spanning 4-domains A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chr 1:208,440,179...208,448,716
Ensembl chr 1:208,440,361...208,448,310
JBrowse link
G Postn periostin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18391768 NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099
JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr 1:207,585,088...207,590,275
Ensembl chr 1:207,587,917...207,589,213
JBrowse link
G Ptger2 prostaglandin E receptor 2 ISO ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:15496426 PMID:16502481 NCBI chr15:18,215,013...18,228,714
Ensembl chr15:18,217,285...18,228,714
JBrowse link
G Ptgir prostaglandin I2 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr 1:77,579,596...77,581,979
Ensembl chr 1:77,579,596...77,581,979
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO protein:increased expression:mast cell
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16502481 PMID:20485159 PMID:9487340 RGD:5143936 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G RT1-Ba RT1 class II, locus Ba susceptibility ISO RGD PMID:25975240 RGD:11074090 NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744
JBrowse link
G RT1-Bb RT1 class II, locus Bb susceptibility ISO RGD PMID:25975240 RGD:11074090 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 susceptibility ISO RGD PMID:25975240 RGD:11074090 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member ISO RGD PMID:21796142 RGD:5147839 NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407
JBrowse link
G Tbx21 T-box transcription factor 21 ISO ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:15806396 PMID:16502481 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831
JBrowse link
G Tbxa2r thromboxane A2 receptor susceptibility ISO DNA:polymorphism: :795T>C (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16502481 PMID:20485159 PMID:15898979 RGD:11059537 NCBI chr 7:8,383,347...8,390,753
Ensembl chr 7:8,383,378...8,388,176
JBrowse link
asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A ISO protein:increased expression:blood, lymphocyte RGD PMID:19484671 RGD:4890020 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 ISO RGD PMID:18931056 RGD:5128825 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase no_association ISO RGD PMID:19771478 PMID:16008680 RGD:5128835, RGD:5128831 NCBI chr 3:10,162,087...10,182,835
Ensembl chr 3:10,162,096...10,191,423
JBrowse link
G Ace angiotensin I converting enzyme susceptibility ISO DNA:polymorphism (human) RGD PMID:19484664 PMID:19383228 RGD:4140913, RGD:4140919 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 ISO DNA:hypermethylation:promoter RGD PMID:19221603 RGD:13831295 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Ada adenosine deaminase susceptibility ISO DNA:polymorphisms (human) RGD PMID:16754522 RGD:5128848 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Adam33 ADAM metallopeptidase domain 33 susceptibility
no_association
disease_progression
ISO mRNA:increased expression:lung
DNA:polymorphism: :p.M764T (human)
DNA:SNPs:introns,exon:7575G>A, 11188A>T, 12433T>C (human)
mRNA:increased expression:bronchus
DNA:SNPs (human)
DNA:SNPs: :multiple (human)
RGD
GAD
PMID:19635592 PMID:17961406 PMID:16893396 PMID:15118671 PMID:17339047 More... RGD:4145360, RGD:4145379, RGD:4145382, RGD:1331525, RGD:4145380, RGD:4145359, RGD:4145378 NCBI chr 3:118,262,395...118,283,461
Ensembl chr 3:118,271,029...118,283,461
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 severity ISO mRNA:increased expression:bronchus
mRNA:increased expression:respiratory tract
RGD PMID:17339047 PMID:20194813 PMID:19373511 RGD:4145380, RGD:5128872, RGD:5128878 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
JBrowse link
G Adcy2 adenylate cyclase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 1:34,375,639...34,822,237
Ensembl chr 1:34,375,895...34,822,236
JBrowse link
G Adcyap1r1 ADCYAP receptor type I ISO CTD Direct Evidence: marker/mechanism CTD PMID:21059121 NCBI chr 4:84,593,558...84,642,700
Ensembl chr 4:84,593,892...84,642,700
JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide susceptibility ISO protein:increased expression:respiratory system fluid/secretion
DNA:SNPs: :rs1154404, rs28730619 (human)
RGD PMID:19395503 PMID:17543375 PMID:19514054 PMID:15919956 RGD:5128891, RGD:5128882, RGD:5128890, RGD:5128892 NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:226,947,466...226,987,591
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO RGD PMID:19168697 RGD:5686821 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adora1 adenosine A1 receptor ISO DNA:SNPs: :1405C>T (human)
protein:increased expression:bronchus
RGD PMID:19019667 PMID:20400685 PMID:17959644 RGD:4890386, RGD:4145444, RGD:5129097 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
JBrowse link
G Adora2a adenosine A2a receptor ISO mRNA:decreased expression:aorta
DNA:SNP (human)
RGD PMID:17293374 PMID:18310516 PMID:19019667 PMID:16339780 RGD:4890380, RGD:4890366, RGD:4890386, RGD:4890385 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Adrb2 adrenoceptor beta 2 susceptibility ISO ClinVar Annotator: match by term: Beta-2-adrenoreceptor agonist, reduced response to
CTD Direct Evidence: marker/mechanism
DNA:SNP: :-1023A>G (human)
DNA:SNPs: :p.R16G, p.Q27E (human)
DNA:SNPs:promoter:multiple (human)
DNA:polymorphism: :p.R16G (human)
DNA:SNP: :p.Q27E (human)
ClinVar
CTD
OMIM
RGD
PMID:8383511 PMID:15284533 PMID:16596417 PMID:1655856 PMID:15118671 More... RGD:5129113, RGD:1331525, RGD:4145081, RGD:4145094, RGD:4145107, RGD:4145108, RGD:4145092, RGD:4145105, RGD:4145061, RGD:4145096 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Ager advanced glycosylation end product-specific receptor treatment
onset
ISO
IDA
IEP
CTD Direct Evidence: marker/mechanism
protein:decreased expression:lung (rat)
CTD
RGD
PMID:33075463 PMID:21920897 PMID:23304218 PMID:23304218 RGD:6767554, RGD:7244279, RGD:7244279 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Agtr1a angiotensin II receptor, type 1a ISO
IMP
RGD PMID:17877756 PMID:19080339 RGD:5147452, RGD:5147457 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Agtr2 angiotensin II receptor, type 2 IEP mRNA, protein:increased expression:lung RGD PMID:19080339 RGD:5147457 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:9600491 PMID:11506308 PMID:15118671 RGD:1331525 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO protein:increased expression:lung RGD PMID:19628725 PMID:18692885 RGD:5509605, RGD:5509784 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
JBrowse link
G Alox5 arachidonate 5-lipoxygenase no_association
susceptibility
treatment
severity
ISO DNA:polymorphism:promoter (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:blood, leukocyte
protein:increased expression:lung
DNA:repeat:promoter (human)
DNA:polymorphism:cds:p.E254K (human)
CTD
OMIM
RGD
PMID:20128419 PMID:9642160 PMID:12911785 PMID:8879219 PMID:11035107 More... RGD:4890407, RGD:5147467, RGD:5147465, RGD:5147462, RGD:4890422, RGD:4890408, RGD:734557, RGD:4890415, RGD:4890413, RGD:4890410 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein susceptibility
no_association
ISO DNA:SNP: :rs10507391 (human)
mRNA:increased expression:blood, leukocyte
DNA:repeat:promoter:-169(A)21 (human)
DNA:substitution, repeat:promoter:-336G>A, -169(A)19-23 (human)
DNA:polymorphisms:intron:IVS2+12C>A, IVS2+105T>C (human)
protein:increased expression:lung
DNA:polymorphism:promoter (human)
DNA:SNPs (human)
RGD PMID:20067482 PMID:9642160 PMID:10527888 PMID:12911785 PMID:15784112 More... RGD:4890405, RGD:5147467, RGD:5147466, RGD:5147465, RGD:5147464, RGD:5147462, RGD:4890422, RGD:4890407, RGD:4890409 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986
JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor ISO protein:increased expression:serum RGD PMID:14621078 RGD:6904149 NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:76,568,094...76,578,331
JBrowse link
G Ang angiogenin severity ISO protein:increased expression:sputum RGD PMID:16478840 RGD:6892719 NCBI chr15:24,317,733...24,323,361 JBrowse link
G Anxa1 annexin A1 ISO RGD PMID:22092555 RGD:7421657 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Areg amphiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15696081 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Arg1 arginase 1 ISO DNA:SNP: :rs2781667 (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (mouse)
mRNA, protein:increased expression:lung, mononuclear cell (human)
CTD
RGD
PMID:19281908 PMID:19800904 PMID:20124949 PMID:12813022 PMID:12813022 RGD:5129205, RGD:4143187, RGD:4143187 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arg2 arginase 2 severity
susceptibility
ISO DNA:SNP: :rs3742879, rs17249437 (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (mouse)
DNA:SNPs (human)
CTD
RGD
PMID:19281908 PMID:20124949 PMID:12813022 PMID:16387594 RGD:5129205, RGD:4143187, RGD:5129207 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Bcl2 BCL2, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:18357729 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bdkrb2 bradykinin receptor B2 onset ISO
IMP
DNA:polymorphism:exon (human)
protein:increased expression:blood, eosinophil
RGD PMID:11517947 PMID:14727005 PMID:8856156 PMID:19038786 RGD:4890456, RGD:4890454, RGD:4891042, RGD:4891028 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
JBrowse link
G Bdnf brain-derived neurotrophic factor susceptibility
severity
ISO protein:decreased expression:blood, eosinophil
DNA:SNP,haplotypes: :rs10767664,rs12273539,rs962369(human)
DNA:polymorphisms: :p.V66M, -270C>T (human)
DNA:polymorphisms: :p.V66M (rs6265) (human)
protein:increased expression:plasma
RGD PMID:12752594 PMID:21723144 PMID:17584309 PMID:19895626 PMID:20874832 More... RGD:4891122, RGD:8655967, RGD:4891067, RGD:4891117, RGD:4891063, RGD:4891123 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bglap bone gamma-carboxyglutamate protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:8429434 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B ISO protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chr 2:230,538,252...230,871,077
Ensembl chr 2:230,541,558...230,871,368
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 ISO protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809
JBrowse link
G C3 complement C3 severity ISO DNA:SNPs: :multiple (human)
protein:increased expression:serum
DNA:SNP: :4896C>T (human)
DNA:SNP:intron:rs11569562 (human)
Interaction with IL4RA
protein:increased expression:respiratory system fluid/secretion
RGD PMID:16355111 PMID:20589464 PMID:15278436 PMID:18566738 PMID:20402389 More... RGD:5129505, RGD:5129519, RGD:5129512, RGD:5129501, RGD:5129537, RGD:5129538, RGD:5129681, RGD:5129517 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G C3ar1 complement C3a receptor 1 severity ISO
IEP
mRNA:increased expression:lung
protein:increased expression:lung, leukocyte
RGD PMID:20045013 PMID:17544263 PMID:20802484 PMID:15940127 PMID:15278436 RGD:5129686, RGD:5129560, RGD:5129681, RGD:5129561, RGD:5129512 NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701
JBrowse link
G C5 complement C5 severity ISO
IDA
mRNA:decreased expression:lung RGD PMID:10973279 PMID:20143644 PMID:20802484 PMID:15278436 PMID:11591795 RGD:5130158, RGD:5129706, RGD:5129681, RGD:5129512, RGD:1600651 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
JBrowse link
G C5ar1 complement C5a receptor 1 severity ISO
IEP
protein:increased expression:lung, leukocyte
protein:increased expression:respiratory tract
RGD PMID:20802484 PMID:17544263 PMID:15940127 PMID:16511606 RGD:5129681, RGD:5129560, RGD:5129561, RGD:5130166 NCBI chr 1:76,948,622...76,959,826 JBrowse link
G Card11 caspase recruitment domain family, member 11 susceptibility ISO RGD PMID:16751370 RGD:11100037 NCBI chr12:13,620,979...13,758,115
Ensembl chr12:13,621,087...13,758,112
JBrowse link
G Carm1 coactivator-associated arginine methyltransferase 1 IEP mRNA:decreased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689
JBrowse link
G Casp1 caspase 1 ISO protein:increased expression:serum RGD PMID:12396474 RGD:5130192 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Cat catalase severity ISO DNA:polymorphism:promoter:-21A>T (human)
CTD Direct Evidence: marker/mechanism
protein:decreased activity:respiratory system fluid/secretion
DNA:polymorphism:promoter:-262C>T (human)
protein:increased expression:erythrocyte
CTD
RGD
PMID:18048809 PMID:19373626 PMID:16622028 PMID:18048809 PMID:19475625 RGD:5130753, RGD:5130867, RGD:5130856, RGD:5130751 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl1 C-C motif chemokine ligand 1 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:20455898 RGD:4891420 NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 susceptibility
treatment
severity
ISO
IDA
IEP
protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
DNA:polymorphism: :p.A23T (human)
mRNA:increased expression:lung
CTD
OMIM
RGD
PMID:16304252 PMID:22932891 PMID:17074272 PMID:9034156 PMID:17845580 More... RGD:5130930, RGD:7248416, RGD:4145461, RGD:4145451, RGD:4145457, RGD:4145392, RGD:4145387, RGD:4891485 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 IEP
ISO
mRNA:increased expression:lung
protein:increased expression:respiratory system fluid/secretion
RGD PMID:15993846 PMID:15947487 PMID:20074456 PMID:20237293 PMID:11160256 RGD:2306304, RGD:4145513, RGD:4145487, RGD:4145486, RGD:4145603 NCBI chr19:10,202,317...10,203,768
Ensembl chr19:10,202,128...10,203,819
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 ISO protein:increased expression:bronchus submucosa, mast cell RGD PMID:16959919 RGD:5130911 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 severity
treatment
ISO
IEP
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (mouse)
DNA:haplotype::-2518A>G (human)
protein:increased expression:lung
CTD
RGD
PMID:19373627 PMID:19373627 PMID:12055264 PMID:25441643 PMID:23454776 More... RGD:4891466, RGD:11528570, RGD:11528569, RGD:8551842, RGD:2307055, RGD:4145509 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 ISO protein:increased expression:respiratory system fluid/secretion
associated with Allergic Rhinitis;protein:increased expression:serum
RGD PMID:18422729 PMID:22469443 RGD:7483597, RGD:7483618 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 ISO
IEP
protein:increased expression:respiratory system fluid/secretion
mRNA, protein:increased expression:respiratory system mucosa, respiratory system fluid/secretion
mRNA:increased expression:lung
RGD PMID:18316417 PMID:10384142 PMID:18684970 PMID:15993846 RGD:4891474, RGD:4891475, RGD:4145489, RGD:2306304 NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400
JBrowse link
G Ccl24 C-C motif chemokine ligand 24 susceptibility ISO DNA:SNPs: :179T>C, 275C>T (human)
protein:increased expression:respiratory system fluid/secretion
DNA:SNP: :1265A>G (human)
DNA:SNPs: :304C>A, 1272A>G (human)
protein:increased expression:plasma
RGD PMID:15207712 PMID:17548626 PMID:12952266 PMID:12761043 PMID:18712274 More... RGD:4891495, RGD:4891484, RGD:4891496, RGD:5130932, RGD:4891483, RGD:4891485, RGD:5130930 NCBI chr12:21,100,835...21,104,832
Ensembl chr12:21,100,835...21,104,893
JBrowse link
G Ccl26 C-C motif chemokine ligand 26 treatment ISO
IDA
protein:increased expression:plasma
DNA:SNPs: :77C>T, 2497T>G (human)
DNA:SNPs: :77C>T, 716A>G, 1579G>A (human)
RGD PMID:16304252 PMID:25399816 PMID:25530546 PMID:15207712 PMID:18712274 RGD:5130930, RGD:11087575, RGD:11081163, RGD:4891495, RGD:4891483 NCBI chr12:21,109,384...21,114,336
Ensembl chr12:21,109,421...21,114,335
JBrowse link
G Ccl27 C-C motif chemokine ligand 27 ISO RGD PMID:19541356 RGD:5130899 NCBI chr 5:56,941,402...56,948,511
Ensembl chr 5:56,941,402...56,948,506
JBrowse link
G Ccl28 C-C motif chemokine ligand 28 ISO mRNA:increased expression:lung (mouse) RGD PMID:16290206 RGD:4892195 NCBI chr 2:51,601,354...51,625,999
Ensembl chr 2:51,601,331...51,625,997
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 ISO RGD PMID:18774390 RGD:5130915 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 susceptibility IEP
ISO
protein:increased expression:smooth muscle cell
CTD Direct Evidence: marker/mechanism
DNA:transition:5' utr:-403G>A (human)
protein:increased expression:lung, secretion (mouse)
CTD
RGD
PMID:8534483 PMID:18208670 PMID:20430255 PMID:20092989 RGD:2307112, RGD:4891381, RGD:4891430 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 ISO RGD PMID:21388664 PMID:19965981 RGD:5130983, RGD:5130979 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 severity ISO mRNA:increased expression:lung
associated with Respiratory Syncytial Virus Infections
RGD PMID:15654816 PMID:15593301 RGD:5688158, RGD:5688159 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Ccr2 C-C motif chemokine receptor 2 susceptibility ISO DNA:SNP:cds:p.V64I (human)
DNA:haplotype:cds:p.V64I(human)
protein:increased expression:lung, dendritic cell (mouse)
RGD PMID:17298432 PMID:23454776 PMID:19917684 RGD:4145110, RGD:8551842, RGD:8549811 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO
IMP
protein:increased expression:respiratory system fluid/secretion, neutrophil
DNA:SNP:exon:51T>C (human)
RGD PMID:18699933 PMID:19017998 PMID:20220260 PMID:16978084 PMID:19657453 More... RGD:4145633, RGD:4145632, RGD:4145638, RGD:4145646, RGD:4145623, RGD:4145618, RGD:1601020 NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 IEP mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chr 8:114,176,256...114,182,155
Ensembl chr 8:114,176,974...114,178,056
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 no_association ISO DNA:frameshift mutation:cds:p.S185_T195del rs333 (human)
DNA:polymorphism, frameshift mutation: :-59029G>A, p.S185_T195del (rs333) (human)
mRNA:increased expression:lung (mouse)
protein:decreased expression:blood, lymphocyte (human)
RGD PMID:20220260 PMID:23454776 PMID:16474097 PMID:18094012 PMID:15256090 RGD:4145638, RGD:8551842, RGD:4892093, RGD:4892088, RGD:4892108 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Ccr6 C-C motif chemokine receptor 6 ISO protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 ISO protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
JBrowse link
G Ccr8 C-C motif chemokine receptor 8 IEP mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chr 8:119,826,332...119,828,292
Ensembl chr 8:119,826,568...119,827,629
JBrowse link
G Ccr9 C-C motif chemokine receptor 9 ISO mRNA, protein:increased expression:blood, mature NK T cell RGD PMID:16210593 RGD:5130925 NCBI chr 8:123,396,157...123,410,199
Ensembl chr 8:123,395,813...123,413,969
JBrowse link
G Cd14 CD14 molecule severity
no_association
susceptibility
ISO DNA:polymorphism:promoter:c. -260C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter:c. -159C>T (human)
DNA:SNPs: :
protein:increased expression:serum|DNA:polymorphism:promoter:c. -159C>T (human)
CTD
RGD
PMID:17607003 PMID:15940135 PMID:15741437 PMID:19096003 PMID:16387800 More... RGD:4144814, RGD:4144815, RGD:4144228, RGD:4144813, RGD:4144208 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd1d1 CD1d1 molecule susceptibility ISO associated with fasciolopsiasis RGD PMID:20304473 RGD:4140417 NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089
JBrowse link
G Cd209c CD209c molecule ISO RGD PMID:21471959 RGD:5131188 NCBI chr12:1,936,233...1,943,841
Ensembl chr12:1,936,396...1,942,040
JBrowse link
G Cd209d CD209d molecule ISO RGD PMID:21471959 RGD:5131188 NCBI chr12:1,891,109...1,897,559
Ensembl chr12:1,891,113...1,901,171
JBrowse link
G Cd274 CD274 molecule treatment ISO associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chr 1:227,116,627...227,137,379
Ensembl chr 1:227,116,649...227,134,450
JBrowse link
G Cd28 Cd28 molecule ISO RGD PMID:21356099 RGD:5131612 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
JBrowse link
G Cd40 CD40 molecule treatment ISO
IDA
IEP
RGD PMID:19220210 PMID:20205594 PMID:20205594 PMID:20941750 PMID:19159017 RGD:5132272, RGD:8547792, RGD:8547792, RGD:4892277, RGD:4144188 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd40lg CD40 ligand severity ISO RGD PMID:9502776 RGD:11352238 NCBI chr  X:135,127,119...135,138,302
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Cd80 Cd80 molecule ISO RGD PMID:21352203 PMID:21051864 PMID:21440530 RGD:5132620, RGD:5132621, RGD:5132619 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
JBrowse link
G Cd86 CD86 molecule treatment ISO
IEP
protein:increased expression:lung, alveolar macrophage (mouse)
protein:increased expression:blood, B cell (human)
protein:increased expression:lung, dendritic cell (rat)
DNA:snp:exon:p.I179V rs2681417 (human)
RGD PMID:20941750 PMID:25344652 PMID:9449507 PMID:20668438 PMID:9551945 More... RGD:4892277, RGD:11354965, RGD:4892555, RGD:4892199, RGD:4892202, RGD:4892280 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdh1 cadherin 1 ISO RGD PMID:21540309 RGD:5132878 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdhr3 cadherin-related family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr 6:49,641,833...49,702,016
Ensembl chr 6:49,641,813...49,702,017
JBrowse link
G Cftr CF transmembrane conductance regulator susceptibility ISO DNA:deletion: :F508del(human) RGD PMID:20298391 RGD:4140387 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Chat choline O-acetyltransferase IEP Protein:decreased expression:lung epithelium RGD PMID:17328924 RGD:5686690 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
JBrowse link
G Chi3l1 chitinase 3 like 1 susceptibility ISO human gene in mouse model
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 7
DNA:snp:5' utr:g.-131C>G rs4950928 (human)
protein:increased secretion:serum (human)
CTD
OMIM
ClinVar
RGD
PMID:18403759 PMID:19414556 PMID:19568425 PMID:18003958 RGD:4892663, RGD:4892630, RGD:4892632 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
JBrowse link
G Chia chitinase, acidic no_association ISO DNA:snps:5' utr, cds:multiple (human)
DNA:snps:multiple (human)
mRNA:increased expression:lung, epithelial cell (human)
mRNA:increased expression:lung (mouse)
RGD PMID:16179638 PMID:20226308 PMID:19548841 PMID:15192232 PMID:14734765 RGD:4996473, RGD:5024922, RGD:5024921, RGD:4985150, RGD:4990463 NCBI chr 2:193,614,374...193,656,532
Ensembl chr 2:193,614,114...193,656,533
JBrowse link
G Chml CHM like Rab escort protein ISO RGD PMID:18343558 RGD:5133238 NCBI chr13:87,613,610...87,615,475
Ensembl chr13:87,589,298...87,619,862
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 ISO RGD PMID:16931638 RGD:5133416 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 ISO DNA:SNP: :rs6962027 (human) RGD PMID:19308904 RGD:5509586 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 severity ISO RGD PMID:20394512 PMID:18348887 RGD:5133437, RGD:5133438 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex ISO RGD PMID:18643924 RGD:5133701 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Clca1 chloride channel accessory 1 susceptibility ISO DNA:SNPs (human) RGD PMID:11296262 PMID:17898169 PMID:15318163 RGD:4145661, RGD:4145653, RGD:4145656 NCBI chr 2:233,938,677...233,964,369
Ensembl chr 2:233,938,677...233,964,369
JBrowse link
G Cldn18 claudin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27215490 NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:100,247,633...100,273,351
JBrowse link
G Cma1 chymase 1 severity
susceptibility
no_association
ISO protein:increased expression:lung epithelium, mast cell (human)
DNA:duplications:3' utr:g.*254-?dupTG, dupGA (human)
DNA:polymorphism:5' utr:g.-1903G>A rs1800875 (human)
RGD PMID:20813890 PMID:15924217 PMID:15248847 RGD:5128804, RGD:1625396, RGD:1625397 NCBI chr15:29,417,451...29,420,233
Ensembl chr15:29,417,451...29,420,233
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO DNA:SNP: :RS242941 (human)
DNA:SNPs: :rs1876828, rs242939, rs242941 (human)
RGD PMID:19663668 PMID:16113459 RGD:5147485, RGD:5147488 NCBI chr10:89,040,203...89,083,481
Ensembl chr10:89,040,203...89,083,481
JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 ISO DNA:SNPs: :multiple (human) RGD PMID:18408560 RGD:5130938 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904
JBrowse link
G Crp C-reactive protein ISO protein:increased expression:serum RGD PMID:21140796 RGD:5131288 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Csf2 colony stimulating factor 2 severity ISO protein:increased expression:lung
protein:increased expression:sputum
RGD PMID:20405019 PMID:9717963 PMID:19213775 RGD:5131473, RGD:10449521, RGD:5131476 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta IMP RGD PMID:17145927 RGD:1601020 NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157
JBrowse link
G Csf3 colony stimulating factor 3 ISO protein:increased expression:lung RGD PMID:21396376 PMID:20405019 RGD:5133731, RGD:5131473 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 severity
treatment
no_association
ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :multiple (human)
DNA:SNP: :rs3087243 (human)
DNA:polymorphism:promoter:-318C>T (human)
DNA:SNPs:promoter, exon:-1147C>T, -318C>T, 49A>G (human)
DNA:polymorphisms:promoter, exon:-318C>T 49A>G (human)
CTD
RGD
PMID:28807506 PMID:15871446 PMID:11726402 PMID:17237396 PMID:15316504 More... RGD:4891529, RGD:11344922, RGD:4891514, RGD:4891519, RGD:4891526, RGD:4891517, RGD:4891522, RGD:4891510, RGD:4891528, RGD:4891516, RGD:4891527, RGD:4891521 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
JBrowse link
G Ctnna3 catenin alpha 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19187332 NCBI chr20:23,614,469...25,200,026
Ensembl chr20:23,623,560...25,199,978
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 ISO protein:increased expression:plasma RGD PMID:14657873 RGD:4891906 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 no_association ISO DNA:SNPs: :p.V249I, rs2669849 (human)
DNA:polymorphisms: :p.V249I, p.T280M (human)
RGD PMID:21037587 PMID:17082760 PMID:17505143 RGD:4891882, RGD:4891895, RGD:4891904 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 severity ISO RGD PMID:20371397 RGD:5134983 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO protein:decreased expression:plasma RGD PMID:17302903 PMID:16602032 PMID:11994485 RGD:5135439, RGD:5135457, RGD:5135452 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21150878 NCBI chr17:8,317,933...8,325,956
Ensembl chr17:8,317,933...8,324,839
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ISO mRNA:increased expression:lung RGD PMID:20045013 RGD:5129686 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 severity ISO RGD PMID:20371397 RGD:5134983 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 ISO mRNA:increased expression:bronchus epithelium RGD PMID:17234659 PMID:9620668 RGD:5135243, RGD:5135265 NCBI chr14:17,310,089...17,312,303
Ensembl chr14:17,310,426...17,313,093
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 ISO RGD PMID:15210824 RGD:5135447 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 susceptibility
severity
ISO DNA:SNP:intron:IVS1+234G>A (human)
protein:decreased expression:respiratory system fluid/secretion, T cell
RGD PMID:18094012 PMID:16043121 PMID:16548899 PMID:17641057 RGD:4892088, RGD:5143934, RGD:5143932, RGD:5135484 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969
JBrowse link
G Cyba cytochrome b-245 alpha chain susceptibility ISO DNA:polymorphism: :-930A>G (human)
DNA:SNPs: :-930A>G, 242C>T, 640A>G (human)
RGD PMID:19459419 PMID:18716406 RGD:4311041, RGD:4772770 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO mRNA, protein:increased expression, decreased activity:lung RGD PMID:12415424 RGD:4892074 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 ISO DNA:polymorphism: :1934G>A (human) RGD PMID:19575027 RGD:5143944 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO mRNA:decreased expression:leukocyte
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:28807506 PMID:20514434 PMID:17081494 RGD:4892076, RGD:4892220 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 no_association
severity
ISO DNA:SNPs:promoter, exon:multiple (human)
DNA:SNPs:promoter:-634C>T, -475A>C, -336A>G (human)
DNA:SNP: :927T>C (human)
mRNA, protein:increased expression:respiratory system mucosa
RGD PMID:16771777 PMID:16630147 PMID:16776674 PMID:8087328 PMID:16387808 More... RGD:4889116, RGD:4784257, RGD:4782072, RGD:4888514, RGD:4843543, RGD:4848936, RGD:4781742, RGD:4781449, RGD:4847129 NCBI chr  X:71,661,415...71,690,158
Ensembl chr  X:71,663,821...71,690,121
JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 ISO DNA:polymorphism: :601A>G (human)
DNA:polymorphism: :-1220A>C (human)
RGD PMID:15475736 PMID:15454733 RGD:5144002, RGD:5144003 NCBI chr15:48,190,251...48,229,906
Ensembl chr15:48,189,073...48,304,136
JBrowse link
G Dcn decorin IEP RGD PMID:16387756 RGD:2311423 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Defb1 defensin beta 1 susceptibility ISO DNA:SNP: :-1816 T>C (human)
DNA:SNPs:5' utr:g.-52G>A, g.-44C>G, g.-20G>A (human)
RGD PMID:15696078 PMID:16435024 RGD:4892263, RGD:4892254 NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604
JBrowse link
G Dnah5 dynein, axonemal, heavy chain 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 2:78,937,788...79,255,551
Ensembl chr 2:78,937,800...79,254,890
JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO DNA,mRNA:hypermethylation,decreased expression:promoter,respiratory tract:
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:23423710 PMID:23196709 RGD:9588646 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dpp10 dipeptidyl peptidase like 10 ISO
IEP
DNA:SNPs (human)
DNA:SNP: :rs10208402 (human)
DNA:SNP:exon (human)
protein:increased expression:bronchus
RGD
GAD
PMID:21103062 PMID:15118671 PMID:19672052 PMID:14566338 PMID:17967935 RGD:4889866, RGD:1331525, RGD:4892275, RGD:4892276, RGD:4892278 NCBI chr13:34,584,420...36,269,619
Ensembl chr13:34,595,868...36,269,292
JBrowse link
G Ebi3 Epstein-Barr virus induced 3 ISO RGD PMID:21255010 RGD:5128488 NCBI chr 9:774,252...787,544
Ensembl chr 9:783,617...787,544
JBrowse link
G Edn1 endothelin 1 ISO Severe Persistent Allergic Asthma; protein:increased secretion:lung (human)
CTD Direct Evidence: marker/mechanism
DNA:transition:intron:g.4124T>C (human)
CTD
RGD
PMID:16981460 PMID:20588001 PMID:11668616 RGD:4144895, RGD:4144869 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A ISO RGD PMID:17448648 PMID:18632188 RGD:4892322, RGD:4892288 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Ednrb endothelin receptor type B IEP
ISO
mRNA:increased expression:bronchus, smooth muscle cell
DNA:polymorphism (human)
RGD PMID:15245576 PMID:17470272 PMID:18632188 RGD:4892324, RGD:4892321, RGD:4892288 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
JBrowse link
G Egfr epidermal growth factor receptor severity IEP
ISO
protein:increased expression:lung epithelium (rat)
protein:increased expression:bronchial epithelium (human)
protein:increased expression:lung epithelium (mouse)
RGD PMID:19954006 PMID:12580917 PMID:21224214 PMID:21072743 RGD:5131870, RGD:5131468, RGD:5131633, RGD:5131642 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 ISO mRNA:increased expression:bronchoalveolar lavage cell (human)
DNA:snp:5' utr:g.-4071A>G rs7729723 (human)
RGD PMID:11254538 PMID:18774390 PMID:18507785 RGD:5131985, RGD:5130915, RGD:5131993 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 no_association ISO RGD PMID:12774215 PMID:11281413 RGD:5129158, RGD:5129157 NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762
JBrowse link
G Ephx1 epoxide hydrolase 1 susceptibility ISO DNA:SNPs:exons:p.Y113H (rs1051740), p.H139R (rs2234922) (human) RGD PMID:17711870 RGD:4889407 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Epx eosinophil peroxidase severity
disease_progression
ISO protein:increased activity:sputum,nasal,pharyngeal mucosa RGD PMID:26645423 PMID:12199967 PMID:20813885 RGD:11574908, RGD:13506892, RGD:13506891 NCBI chr10:72,666,865...72,677,952
Ensembl chr10:72,666,865...72,677,952
JBrowse link
G Esr2 estrogen receptor 2 IEP mRNA:decreased expression:lung (rat) RGD PMID:18375789 RGD:8694127 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G F2 coagulation factor II ISO protein:increased expression:plasma
associated with Rhinosinusitis, associated with Nasal Polyps;protein:increased expression:nasal mucus
RGD PMID:21658190 PMID:21711961 RGD:5147753, RGD:5147783 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F2rl1 F2R like trypsin receptor 1 ISO RGD PMID:19864598 RGD:4892589 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
G F7 coagulation factor VII treatment IDA RGD PMID:24523826 RGD:11040539 NCBI chr16:76,489,779...76,500,636
Ensembl chr16:76,489,717...76,500,610
JBrowse link
G Fas Fas cell surface death receptor IEP mRNA:increased expression:eosinophil RGD PMID:16337971 RGD:1600350 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fcer1a Fc epsilon receptor Ia severity ISO Asthma symptoms persistent despite steroids in humans
Fatal asthma subjects
RGD PMID:20937062 PMID:21388666 RGD:5128717, RGD:5128711 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351
JBrowse link
G Fcgr2a Fc gamma receptor 2A ISO protein:increased expression:alveolar macrophage RGD PMID:9117017 RGD:5147982 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
JBrowse link
G Fcgr2b Fc gamma receptor 2B ISO RGD PMID:20179765 RGD:11344929 NCBI chr13:83,191,253...83,207,776
Ensembl chr13:83,193,163...83,207,778
JBrowse link
G Fcgr3a Fc gamma receptor 3A susceptibility ISO DNA:polymorphism:exon:p.F158V(rs396991)(human) RGD PMID:18199088 RGD:5508449 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921
JBrowse link
G Fga fibrinogen alpha chain treatment IDA RGD PMID:24523826 RGD:11040539 NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 ISO ClinVar Annotator: match by term: Asthma ClinVar NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
JBrowse link
G Foxp3 forkhead box P3 treatment ISO
IEP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:27965764 PMID:29317916 PMID:28944907 PMID:27633092 RGD:38549365, RGD:38548920 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Gata3 GATA binding protein 3 ISO
IEP
RGD PMID:9949310 PMID:18186587 RGD:5128802, RGD:5128803 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Gc GC, vitamin D binding protein ISO protein, mRNA:increased expression:bronchoalveolar lavage fluid: RGD PMID:21169467 PMID:21169467 RGD:5509920, RGD:5509920 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 susceptibility ISO DNA:polymorphism:promoter: -69C>T (human) RGD PMID:20374258 RGD:5490988 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gstm1 glutathione S-transferase mu 1 resistance
susceptibility
ISO DNA:deletion: :
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16870661 PMID:18988661 PMID:17651144 PMID:21051083 PMID:11075422 RGD:4142509, RGD:5490962, RGD:4140921 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm3 glutathione S-transferase mu 3 ISO DNA:polymorphism RGD PMID:17550934 PMID:11470996 RGD:5135038, RGD:5135039 NCBI chr 2:195,590,450...195,612,578
Ensembl chr 2:195,607,289...195,612,475
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 ISO DNA:polymorphism RGD PMID:11470996 PMID:17550934 RGD:5135038 RGD:5135039 NCBI chr 2:195,531,627...195,534,562
Ensembl chr 2:195,531,495...195,534,553
JBrowse link
G Gsto2 glutathione S-transferase omega 2 susceptibility ISO DNA:polymorphism:exon:p. N142D (human) RGD PMID:20374258 RGD:5490988 NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866
JBrowse link
G Gstp1 glutathione S-transferase pi 1 severity
susceptibility
disease_progression
no_association
ISO DNA:polymorphism:exon:p.I105V (rs1695) (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs:exons:p.I105V (rs1695), A114V (rs1138272) (human)
DNA:SNPs:intron,exon:(rs749174), (rs1138272)(human)
DNA:SNPs: :p.I105V, p.A114V (human)
DNA:polymorphism:exon:p.I105V (human)
DNA:SNP: :p.A114V (human)
CTD
RGD
PMID:11994713 PMID:16870661 PMID:18988661 PMID:24117884 PMID:29411558 More... RGD:4142526, RGD:5490999, RGD:5490991, RGD:5490985, RGD:4140951, RGD:4142519, RGD:4140946, RGD:4140947 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility ISO DNA:deletion: : RGD PMID:15300848 PMID:21051083 PMID:11075422 RGD:4142539, RGD:5490962, RGD:4140921 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO RGD PMID:20628202 RGD:5128851 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 ISO RGD PMID:17517968 RGD:5135525 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137
JBrowse link
G Hdac2 histone deacetylase 2 ISO mRNA:decreased expression:macrophage: RGD PMID:20538962 RGD:9590321 NCBI chr20:40,548,250...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Hdc histidine decarboxylase ISO associated with Rhinitis;DNA:SNP: :p.E644D (rs2073440) (human) RGD PMID:20608921 RGD:5128884 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment ISO RGD PMID:18160846 RGD:10402541 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:20084838 RGD:5508450 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmox1 heme oxygenase 1 severity ISO CTD Direct Evidence: marker/mechanism
mRNA;protein:increased expression:Leukocytes, Mononuclear
CTD
RGD
PMID:18048809 PMID:20596599 PMID:16196283 RGD:4145403, RGD:4145408 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnmt histamine N-methyltransferase no_association
susceptibility
ISO ClinVar Annotator: match by term: Asthma, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
OMIM
CTD
RGD
PMID:10752634 PMID:10803682 PMID:16205835 PMID:17651147 PMID:15693910 More... RGD:5128888, RGD:5128883, RGD:5128885, RGD:5128881, RGD:5128887 NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012
JBrowse link
G Hp haptoglobin ISO RGD PMID:21471098 PMID:21169467 RGD:5144151, RGD:5509920 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11932298 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25322896 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO
IEP
mRNA:increased expression:aorta (mouse)
CTD Direct Evidence: marker/mechanism
protein:increased secretion:lung (human)
protein:increased expression:lung, serum (rat)
CTD
RGD
PMID:17014439 PMID:25003170 PMID:20400685 PMID:20205697 PMID:20953388 RGD:4145444, RGD:4145509, RGD:4145331 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifng interferon gamma treatment
resistance
ISO protein:increased expression:sputum RGD
GAD
PMID:20817868 PMID:12396623 PMID:15118671 PMID:19542437 PMID:20953328 RGD:4145651, RGD:10755706, RGD:1331525, RGD:5128479, RGD:4145525 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ifngr1 interferon gamma receptor 1 ISO DNA: SNP: Leu467Pro RGD PMID:21737883 PMID:12851715 RGD:6480255, RGD:6480431 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785
JBrowse link
G Ifnl1 interferon, lambda 1 exacerbates ISO associated with common cold;mRNA:decreased expression:sputum (human)
associated with common cold;protein:increased expression: nasal cavity (human)
RGD PMID:25784275 PMID:22135341 RGD:126848770, RGD:126848775 NCBI chr 1:83,798,651...83,800,297
Ensembl chr 1:83,798,703...83,800,235
JBrowse link
G Ifnl3 interferon, lambda 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22295096 NCBI chr 1:83,814,456...83,816,096
Ensembl chr 1:83,814,564...83,816,096
JBrowse link
G Ikzf3 IKAROS family zinc finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25256354 NCBI chr10:83,460,564...83,553,591
Ensembl chr10:83,465,745...83,553,591
JBrowse link
G Il10 interleukin 10 treatment
susceptibility
ISO
IEP
IGI
CTD Direct Evidence: marker/mechanism
DNA:polymorphism: :-627C>A (human)
protein:decreased expression:plasma
CTD
RGD
PMID:29317916 PMID:20237464 PMID:21998459 PMID:12938145 PMID:20121766 More... RGD:4140471, RGD:11046261, RGD:4143221, RGD:4140451, RGD:4140459, RGD:4140421, RGD:5131623 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il12a interleukin 12A ISO RGD PMID:17056578 PMID:17548618 RGD:4438438, RGD:4373570 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il12b interleukin 12B severity
susceptibility
ISO DNA:polymorphisms:introns:
DNA:polymorphisms:promoter, 3'utr:
DNA:polymorphism:promoter
RGD PMID:15322986 PMID:16210052 PMID:12241719 RGD:1600043, RGD:4145438, RGD:4145428 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il13 interleukin 13 susceptibility
severity
no_association
ISO
IMP
IDA
IEP
ClinVar Annotator: match by term: Asthma, susceptibility to
CTD Direct Evidence: marker/mechanism
associated with Dermatitis, Atopic;DNA, protein:SNP, increased expression:promoter, serum:-1112C>T (human)
DNA:polymorphism: :-1512A>C, -1112C>T, 2044G>A (human)
mRNA, protein:increased expression:esophagus, Bronchoalveolar Lavage Fluid
protein:increased expression:serum
DNA:polymorphism:cds:p.R130Q (human)
DNA:polymorphisms:promoters,exon4: rs1881457, rs1800925, rs20541 (human)
DNA:polymorphism: :p. R110Q (human)
DNA:SNP: :c. -646A>G (human)
DNA:polymorphism: :c. 1923C>T (human)
protein:increased expression:sputum
DNA:polymorphism:promoter:c. -1055C>T (human)
DNA:polymorphisms: :rs20541, rs1295685(human)
DNA:polymorphism:3'utr:c.4738G>A (human)
DNA:polymorphism: :c.-1055C>T (human)
DNA:polymorphism: :c. 2044G>A (human)
ClinVar
OMIM
CTD
RGD
PMID:10699178 PMID:11588017 PMID:11709756 PMID:12847555 PMID:12928861 More... RGD:4206706, RGD:8549509, RGD:4892639, RGD:2301686, RGD:4145453, RGD:2307110, RGD:4145508, RGD:4763153, RGD:4145639, RGD:4763761, RGD:4145601, RGD:4145664, RGD:4321828, RGD:4146241, RGD:4145775, RGD:4145777, RGD:4220633, RGD:4145534, RGD:4765128, RGD:4145593, RGD:4145776 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 no_association ISO mRNA:increased expression:bronchus
DNA:polymorphisms:promoter, 3' utr:-281T>G, 1365A>G (human)
DNA:polymorphism: :1398A>G (human)
DNA:polymorphism: :1050C>T (human)
RGD PMID:20383033 PMID:17392323 PMID:18480254 PMID:17006604 PMID:10686479 More... RGD:4892646, RGD:4892650, RGD:4892647, RGD:4892639, RGD:4892655, RGD:4892654 NCBI chr  X:115,348,860...115,408,682
Ensembl chr  X:115,348,860...115,408,681
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 ISO mRNA:increased expression:bronchus
protein:increased expression:serum
RGD PMID:20383033 PMID:21462799 PMID:17885690 RGD:4892646, RGD:8549521, RGD:4892649 NCBI chr  X:111,002,590...111,074,053
Ensembl chr  X:111,002,592...111,072,381
JBrowse link
G Il15 interleukin 15 no_association ISO DNA:SNPs: :multiple (human) RGD PMID:19133918 PMID:16629787 PMID:11160248 PMID:15843549 PMID:15131572 RGD:5000760, RGD:4984421, RGD:4990462, RGD:5000757, RGD:5000758 NCBI chr19:25,640,013...25,706,818
Ensembl chr19:25,640,251...25,706,820
JBrowse link
G Il16 interleukin 16 no_association
severity
ISO DNA:SNP:promoter:-295T>C (human)
associated with Rhinitis;protein:increased expression:respiratory system fluid/secretion
protein:increased expression:serum
RGD PMID:10585533 PMID:16387589 PMID:15784111 PMID:16734115 PMID:12872394 RGD:5024937, RGD:5024934, RGD:5024935, RGD:5024928, RGD:5024930 NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130
JBrowse link
G Il17a interleukin 17A susceptibility IEP
ISO
mRNA,protein:increased expression:Leukocytes, Mononuclear, lung, serum
protein:increased expression:sputum
protein:increased expression:alveolar macrophage
DNA:SNP:promoter:rs2275913 (human)
RGD PMID:18060619 PMID:20351038 PMID:15730730 PMID:18941201 PMID:20437253 RGD:4839043, RGD:4888527, RGD:4889114, RGD:4889152, RGD:4889139 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il17rb interleukin 17 receptor B ISO associated with Picornaviridae Infections RGD PMID:25273095 RGD:39128256 NCBI chr16:5,180,431...5,194,125
Ensembl chr16:5,180,432...5,194,125
JBrowse link
G Il18 interleukin 18 severity
susceptibility
disease_progression
ISO DNA:SNPs:Promoter:c. -607C>A (rs1946518), -137G/C (rs187238) (human)
DNA:SNP:promoter:c.and -137G>C (rs187238)(human)
protein:increased expression:serum
DNA:SNP:promoter: c.-380C>G (rs5744247)(human)
DNA:polymorphism: :c. -105A>C (human)
RGD PMID:17767553 PMID:16433859 PMID:18826499 PMID:11174201 PMID:20497957 More... RGD:4889585, RGD:4889923, RGD:4889908, RGD:4889863, RGD:4889898, RGD:4889900, RGD:4889910 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il18r1 interleukin 18 receptor 1 ISO DNA:SNP: :rs3771166 (human)
DNA:SNPs: :multiple (human)
RGD PMID:19910030 PMID:20860503 PMID:18382474 PMID:11972614 PMID:18774397 RGD:5024945, RGD:5024942, RGD:5024947, RGD:5024948, RGD:5024946 NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715
JBrowse link
G Il19 interleukin 19 ISO protein:increased expression:serum RGD PMID:15557163 RGD:5037236 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473
JBrowse link
G Il1a interleukin 1 alpha ISO DNA:polymorphisms: : RGD PMID:18763028 RGD:4142802 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta susceptibility ISO DNA:polymorphism: :-511C>T (human)
CTD Direct Evidence: marker/mechanism
protein:decreased expression:neutrophil
CTD
RGD
PMID:9176529 PMID:18926055 PMID:19842845 PMID:19684087 RGD:4142864, RGD:4142830, RGD:4142836 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 susceptibility
severity
ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs1420101 (human)
DNA:SNPs:intron:rs1420089, rs1861245,rs1946131 (human)
DNA:SNP: :rs10197862 (human)
DNA:SNP: :rs1041973 (human)
CTD
RGD
PMID:19198610 PMID:21150878 PMID:21804549 PMID:24241537 PMID:27472835 More... RGD:5144235, RGD:5144245, RGD:5144244, RGD:5144243, RGD:5144242, RGD:5144240, RGD:5144239, RGD:5144237 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256
JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility
severity
ISO DNA:SNP: :rs2234678 (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :multiple (human)
DNA:SNPs: :rs447713, rs3087271 (human)
protein:increased expression:plasma
DNA, protein:repeat, decreased expression (human)
DNA:polymorphism:intron (human)
CTD
RGD
PMID:9176529 PMID:17107994 PMID:15020290 PMID:16409203 PMID:16724092 More... RGD:4143208, RGD:4143216, RGD:4143163, RGD:4143209, RGD:4143225, RGD:4143224, RGD:4142864, RGD:4142802 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il2 interleukin 2 susceptibility ISO DNA:SNP:promoter:rs2069762(human) RGD PMID:20926789 PMID:16333313 RGD:4889118, RGD:8663473 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il21 interleukin 21 ISO DNA:SNP:exon:5250C>T (human) RGD PMID:18802358 RGD:5147396 NCBI chr 2:120,119,598...120,126,941
Ensembl chr 2:120,119,444...120,126,996
JBrowse link
G Il22 interleukin 22 treatment
severity
ISO
IMP
mRNA:increased expression:blood, mononuclear cell
protein:increased expression:serum
RGD PMID:21789181 PMID:21998459 PMID:21535180 PMID:21297073 RGD:5147401, RGD:11046261, RGD:5147409, RGD:5147403 NCBI chr 7:53,801,206...53,805,673
Ensembl chr 7:53,801,206...53,806,186
JBrowse link
G Il23r interleukin 23 receptor ISO RGD PMID:19935773 RGD:5037240 NCBI chr 4:96,580,568...96,672,540
Ensembl chr 4:96,580,714...96,674,021
JBrowse link
G Il25 interleukin 25 ISO mRNA, protein:increased expression:lung RGD PMID:25273095 RGD:39128256 NCBI chr15:28,408,842...28,411,676
Ensembl chr15:28,408,842...28,411,893
JBrowse link
G Il27 interleukin 27 susceptibility
treatment
ISO DNA:SNP: :g.-964A>G (human)
protein:increased expression:sputum
RGD PMID:17318299 PMID:26595888 PMID:17878337 PMID:19542437 PMID:20817868 RGD:5128485, RGD:11076728, RGD:5128491, RGD:5128479, RGD:4145651 NCBI chr 1:181,173,108...181,178,720
Ensembl chr 1:181,173,372...181,178,582
JBrowse link
G Il27ra interleukin 27 receptor subunit alpha ISO RGD PMID:16081811 RGD:5128496 NCBI chr19:24,109,698...24,121,977
Ensembl chr19:24,109,972...24,121,938
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha IDA
ISO
RGD PMID:17351063 PMID:20525707 PMID:21377197 RGD:2325990, RGD:5147445, RGD:5147437 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
JBrowse link
G Il2rb interleukin 2 receptor subunit beta ISO DNA:SNP: :rs2284033 (human) RGD PMID:20860503 PMID:18641329 RGD:5024942, RGD:5147447 NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054
JBrowse link
G Il3 interleukin 3 susceptibility ISO DNA:SNP: :rs40401(human)
DNA:polymorphism:cds:+79T>C(S27P)(human)
RGD PMID:24684517 PMID:15372320 RGD:13506914, RGD:13506916 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
JBrowse link
G Il33 interleukin 33 treatment
severity
ISO CTD Direct Evidence: marker/mechanism
associated with viral pneumonia;
associated with fungal infectious disease
CTD
RGD
PMID:19198610 PMID:21804549 PMID:24241537 PMID:27472835 PMID:29067999 More... RGD:39939002, RGD:39938968 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Il4 interleukin 4 treatment
no_association
ISO
IEP
DNA:polymorphism (human)
CTD Direct Evidence: marker/mechanism
mRNA, protein:increase expression:leukocyte, serum
protein:increased expression:lung
DNA:SNP: :589C>T (human)
protein:increased expression:respiratory system fluid/secretion
mRNA:increased expression:lung, spleen
CTD
RGD
PMID:18357729 PMID:21103062 PMID:24946644 PMID:24450480 PMID:18211752 More... RGD:4889866, RGD:10402799, RGD:10402791, RGD:2317290, RGD:5128560, RGD:5128502, RGD:5128500, RGD:5128557 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il4r interleukin 4 receptor susceptibility
severity
disease_progression
ISO
ISS
DNA:mutation:cds:p.Q576R (mouse)
OMIM:600807
DNA:SNPs: :multiple
DNA:polymorphism:cds:p.I50V (human)
DNA:SNPs:cds:p. I75V, Q576R (human)
DNA:polymorphism::-1902G/A (human)
protein:increased secretion:plasma|DNA:polymorphism:promoter:c.-3223C>T (human)
DNA:polymorphism:cds:p.Q576R (human)
DNA:SNPs:cds:p.E375A, Q551R (human)
DNA:polymorphism:cds:p. S478P (human)
DNA:polymorphism:cds:p.Q551R (human)
MouseDO
RGD
PMID:19770271 PMID:17823973 PMID:18425216 PMID:12133990 PMID:20868478 More... RGD:4890003, RGD:4890347, RGD:4890346, RGD:4890404, RGD:4890387, RGD:4890406, RGD:4890351, RGD:4890402, RGD:4890349, RGD:4890024, RGD:5128553, RGD:5128514, RGD:4890352, RGD:4890348 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
JBrowse link
G Il5 interleukin 5 treatment
disease_progression
IDA
ISO
IEP
IMP
CTD Direct Evidence: marker/mechanism
protein:increased expression:lungs, respiratory system fluid/secretion
protein: increased levels: sputum
protein:increased expression:respiratory system fluid/secretion
DNA:polymorphism:promoter:-703C>T (human)
CTD
RGD
PMID:7540862 PMID:23266719 PMID:17074272 PMID:25008888 PMID:11159041 More... RGD:4145461, RGD:11354973, RGD:5687189, RGD:5687144, RGD:5687140, RGD:4890947, RGD:4890948, RGD:4890963, RGD:4890940, RGD:4890962, RGD:4890938 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il5ra interleukin 5 receptor subunit alpha ISO DNA:SNP: :c.25091G>A (human)
DNA:SNPs (human)
RGD PMID:20513521 PMID:20592918 PMID:17276963 PMID:10848907 PMID:10224351 More... RGD:5128625, RGD:5128614, RGD:5128617, RGD:5128627, RGD:5128623, RGD:5128626 NCBI chr 4:139,630,652...139,664,593
Ensembl chr 4:139,632,066...139,668,544
JBrowse link
G Il6 interleukin 6 ISO
IEP
CTD Direct Evidence: marker/mechanism
associated with Hypersensitivity;protein:increased expression:sputum
protein:increased expression:lung
CTD
RGD
PMID:29902480 PMID:21115736 PMID:20840469 PMID:20816188 PMID:20658762 RGD:5128630, RGD:4143265, RGD:4143266, RGD:4143271 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6r interleukin 6 receptor ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:29902480 PMID:17496315 PMID:21115736 RGD:5128662, RGD:5128630 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Il9 interleukin 9 ISO protein:increased expression:respiratory system fluid/secretion
protein:increased expression:sputum, macrophage, cytoplasm
RGD PMID:12153980 PMID:17446528 PMID:15531759 PMID:15303135 PMID:21356110 RGD:5128700, RGD:5128686, RGD:5128690, RGD:5128691, RGD:5128707 NCBI chr17:8,111,772...8,114,895
Ensembl chr17:8,111,772...8,114,895
JBrowse link
G Il9r interleukin 9 receptor ISO RGD PMID:10629460 RGD:5128704 NCBI chr10:15,431,706...15,444,144
Ensembl chr10:15,431,706...15,441,990
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 susceptibility ISO ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 5
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:17503328 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121
JBrowse link
G Irf1 interferon regulatory factor 1 no_association
susceptibility
ISO DNA:polymorphisms:promoter, cds:-300G>T, 4396A>G, 6355G>A (human)
protein:increased expression:respiratory tract epithelium
DNA:repeat:intron (human)
RGD PMID:11069564 PMID:10225979 PMID:16961714 RGD:5128726, RGD:5128723, RGD:5128724 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Irf3 interferon regulatory factor 3 ISO RGD PMID:20673978 RGD:5128793 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
JBrowse link
G Itgb3 integrin subunit beta 3 ISO DNA:SNPs: : RGD PMID:17556058 RGD:5037230 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Itgb6 integrin subunit beta 6 ISS OMIM:600807 MouseDO NCBI chr 3:45,046,295...45,170,532
Ensembl chr 3:45,048,044...45,121,671
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 IDA RGD PMID:21777465 RGD:5147661 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
JBrowse link
G Kdr kinase insert domain receptor ISO associated with Rhinitis,Allergic,Seasonal;protein:increased expression:nasal cavity of mucosa: RGD PMID:20921519 PMID:17651148 RGD:5684385, RGD:8551771 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Kif3a kinesin family member 3a ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr10:37,725,930...37,761,183
Ensembl chr10:37,725,970...37,759,191
JBrowse link
G Krt19 keratin 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15478392 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Lep leptin ISO protein:increased expression:plasma RGD PMID:19705789 RGD:5128781 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lgals3 galectin 3 treatment ISO RGD PMID:16424226 RGD:9685213 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Lta lymphotoxin alpha susceptibility
no_association
ISO DNA:polymorphisms:promoter
DNA:polymorphism:intron
RGD PMID:15969671 PMID:18947013 PMID:12530118 PMID:17536219 RGD:4143373, RGD:4143370, RGD:4143254, RGD:4143371 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859
JBrowse link
G Lta4h leukotriene A4 hydrolase IEP mRNA:increased expression:lung, cerebral cortex (rat) RGD PMID:15715933 RGD:2316607 NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600
JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO associated with Bronchiolitis;DNA:polymorphism:exon:
DNA:SNP:cds:p.G54D(human)
RGD PMID:22512728 PMID:22674410 RGD:8693709, RGD:12910828 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mefv MEFV innate immuity regulator, pyrin susceptibility ISO DNA:mutations:exons RGD PMID:18219832 RGD:5129186 NCBI chr10:11,786,948...11,796,977
Ensembl chr10:11,787,422...11,796,973
JBrowse link
G Mif macrophage migration inhibitory factor severity ISO
IDA
protein:increased expression:bronchoalveolar lavage fluid
DNA:SNP:promoter:rs755622(human)
DNA:repeats:promoter
RGD PMID:9637721 PMID:17373669 PMID:19317738 PMID:16186482 PMID:16455830 RGD:4891043, RGD:4891035, RGD:4891059, RGD:4891052, RGD:1641985 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24469321 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp10 matrix metallopeptidase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16926187 NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO
IEP
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
protein:increased expression:lung
DNA:SNP: : rs2664538(human)
mRNA, protein:increased expression:lung
CTD
RGD
PMID:11742282 PMID:15131573 PMID:21439806 PMID:19361849 PMID:20181264 More... RGD:5129204, RGD:5129687, RGD:5130859, RGD:2325953, RGD:5129522 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpo myeloperoxidase susceptibility ISO DNA:polymorphism: :−463G > A (human)
protein:increased expression:serum
RGD PMID:19544176 PMID:10731862 RGD:5130989, RGD:5130994 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Ms4a2 membrane spanning 4-domains A2 susceptibility ISO DNA:SNPs:multiple:, rs573790, rs2583476, rs569108
DNA:SNPs: : rs556917, rs502581, rs502419 (human)
DNA:SNP: : -109C>T (human)
Atopy and bronchial hyperresponsiveness, OMIM:147050
RGD PMID:19218813 PMID:21320344 PMID:19862939 PMID:8817330 RGD:5131151, RGD:5131149, RGD:5131092, RGD:1599903 NCBI chr 1:208,440,179...208,448,716
Ensembl chr 1:208,440,361...208,448,310
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO DNA:transition:cds:g.677C>T (human) RGD PMID:20456312 RGD:4891145 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Muc1 mucin 1, cell surface associated ISO protein:increased expression:serum RGD PMID:11802251 RGD:5131281 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming ISO associated with hypersensitivity RGD PMID:11062147 PMID:14594655 RGD:5131178, RGD:7349354 NCBI chr 1:196,796,257...196,831,740
Ensembl chr 1:196,799,517...196,831,756
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming treatment IEP
ISO
mRNA,protein:increased expression:lung
mRNA, protein:increased expression:lung
RGD PMID:17590487 PMID:21549818 PMID:21780541 PMID:14594655 PMID:17698377 RGD:2324962, RGD:7364729, RGD:7349407, RGD:7349354, RGD:5131204 NCBI chr 1:196,864,375...196,896,475
Ensembl chr 1:196,864,336...196,896,475
JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming ISO protein:altered expression:sputum RGD PMID:11802783 PMID:11587997 RGD:5131252, RGD:7364763 NCBI chr 1:196,916,861...196,948,830
Ensembl chr 1:196,916,825...196,949,250
JBrowse link
G Myb MYB proto-oncogene, transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor ameliorates ISO RGD PMID:26882889 RGD:11531666 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Mylk myosin light chain kinase ISO RGD PMID:17472811 RGD:4891492 NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
JBrowse link
G Nat2 N-acetyltransferase 2 susceptibility ISO DNA:polymorphisms: :
Asthma, Aspirin-Induced; DNA:polymorphism: :
RGD PMID:16924569 PMID:20602614 RGD:5131606, RGD:5131600 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 severity ISO mRNA:increased expression:bronchoalveolar lavage cell, peripheral blood mononuclear cell (human) RGD PMID:21514635 RGD:6893376 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Ngf nerve growth factor severity ISO protein:increased expression:blood, eosinophil
protein:increased expression:lung, serum
RGD PMID:12752594 PMID:17164945 PMID:17497413 PMID:11737043 RGD:4891122, RGD:4891108, RGD:4891068, RGD:4891123 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Ngfr nerve growth factor receptor ISO RGD PMID:16603479 PMID:12540484 RGD:5144070, RGD:5144072 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 susceptibility ISO DNA:SNP: :rs2075817 (human)
DNA:insertion:cds:
RGD PMID:16918516 PMID:15718249 RGD:5131519, RGD:5131518 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 susceptibility ISO DNA:polymorphisms:intron, exon/3'UTR (rs1077861, rs3135500) (human) RGD PMID:16008671 PMID:21051079 RGD:5131477, RGD:5508757 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G Nos1 nitric oxide synthase 1 susceptibility ISO DNA:repeats:exon
DNA:repeats:intron
DNA:repeats: :
RGD PMID:10833424 PMID:14767694 PMID:10673365 PMID:20609134 RGD:5132860, RGD:5132615, RGD:5132869, RGD:5132863 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos2 nitric oxide synthase 2 disease_progression
severity
no_association
ISO
IEP
IMP
protein:increased expression:lung, bronchoalveolar lavage fluid
CTD Direct Evidence: marker/mechanism
protein:increased expression, increased activity:lung (rat)
DNA:repeats:promoter
associated with Rhinitis, Allergic, Seasonal; protein:increased expression:nasal mucosa
DNA:SNP:exon:p.S608L (human)
DNA:repeats:promoter, introns (human)
mRNA:increased expression:monocyte
DNA:repeat:promoter
CTD
RGD
PMID:19800904 PMID:17161822 PMID:21847581 PMID:18714530 PMID:18254476 More... RGD:4891927, RGD:5509073, RGD:4891508, RGD:4891910, RGD:4891925, RGD:4891924, RGD:4891419, RGD:4891953, RGD:4891957, RGD:4891480 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility ISO DNA:snps, repeat, haplotype:promoter, introns, exons:multiple (human)
DNA:polymorphisms:promoter:c. -786C>T, -691C>T (human)
DNA:repeats:intron
RGD PMID:18486767 PMID:16837812 PMID:16081038 RGD:4892053, RGD:4892058, RGD:4892062 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Npsr1 neuropeptide S receptor 1 susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 2
CTD
OMIM
ClinVar
RGD
PMID:15073379 PMID:15710598 PMID:15764725 PMID:16926187 PMID:17702965 More... RGD:4891923, RGD:4891922, RGD:4891921 NCBI chr 8:22,606,946...22,831,558
Ensembl chr 8:22,606,946...22,831,558
JBrowse link
G Npy neuropeptide Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:9731035 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 susceptibility ISO DNA:SNP:exon:c. 609C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:c.609C>T (human)
CTD
RGD
PMID:20049212 PMID:19027876 PMID:19591959 RGD:5135006, RGD:5135005 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 treatment
susceptibility
severity
ISO
IDA
DNA:polymorphism:intron
protein:increased expression, decreased activity:leukocyte, mononuclear
RGD PMID:18396779 PMID:20727335 PMID:21113676 PMID:18799869 PMID:15295049 RGD:4892328, RGD:7174728, RGD:4892568, RGD:4892594, RGD:4892609 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Ntf3 neurotrophin 3 ISO protein:increased expression:lung, serum RGD PMID:11737043 PMID:17497413 RGD:4891123, RGD:4891068 NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596
JBrowse link
G Ntf4 neurotrophin 4 ISO protein:increased expression:lung, serum RGD PMID:17497413 RGD:4891068 NCBI chr 1:95,893,560...95,896,391
Ensembl chr 1:95,893,457...95,897,243
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 ISO
IEP
mRNA:increased expression:lung: RGD PMID:20934630 PMID:16708804 RGD:5684766, RGD:5684772 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21150878 PMID:25256354 NCBI chr10:83,590,052...83,598,620
Ensembl chr10:83,590,071...83,598,620
JBrowse link
G P2ry12 purinergic receptor P2Y12 ISO RGD PMID:22010907 PMID:19822647 RGD:6480532, RGD:6480533 NCBI chr 2:143,481,468...143,523,340
Ensembl chr 2:143,481,430...143,523,361
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased activation:lung, blood, mononuclear cell
CTD
RGD
PMID:18261157 PMID:12594058 PMID:26205779 PMID:26205779 RGD:5683910, RGD:11073727, RGD:11073727 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pdcd1 programmed cell death 1 treatment ISO associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937
JBrowse link
G Pde4b phosphodiesterase 4B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 5:116,799,827...117,367,707
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Pde4d phosphodiesterase 4D ISO CTD Direct Evidence: marker/mechanism CTD PMID:19426955 PMID:21611147 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884
JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO
IMP
protein: increased expression RGD PMID:21216974 PMID:21216974 RGD:6483071, RGD:6483071 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pgf placental growth factor ISO RGD PMID:22268141 RGD:6483605 NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma ISO RGD PMID:18754810 RGD:6482695 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043
JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 IMP RGD PMID:18188456 RGD:8693422 NCBI chr 8:19,189,408...19,200,785
Ensembl chr 8:19,189,373...19,200,785
JBrowse link
G Pla2g4a phospholipase A2 group IVA IEP RGD PMID:15557087 RGD:1642462 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Pla2g7 phospholipase A2 group VII susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Asthma and atopy, susceptibility to
OMIM
CTD
ClinVar
RGD
PMID:10733466 PMID:15115767 PMID:10733466 RGD:1581025 NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476
JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:21912604 PMID:18519237 RGD:4892037 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:22205926 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
JBrowse link
G Prf1 perforin 1 ISO
IDA
RGD PMID:22250087 PMID:21426642 RGD:6482815, RGD:6482818 NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701
JBrowse link
G Prg2 proteoglycan 2 severity
disease_progression
no_association
ISO mRNA:increased expression:eosinophil:
associated with cough;protein:increased expression:sputum:
associated with viral infection;mRNA:increased expression:sputum:
RGD PMID:16982448 PMID:22022864 PMID:24450586 PMID:11067904 RGD:13506941, RGD:13506944, RGD:13506943, RGD:13506942 NCBI chr 3:70,062,535...70,066,102
Ensembl chr 3:70,062,535...70,066,101
JBrowse link
G Prmt1 protein arginine methyltransferase 1 IEP mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345
JBrowse link
G Prmt2 protein arginine methyltransferase 2 IEP mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chr20:12,394,748...12,420,643
Ensembl chr20:12,394,798...12,420,643
JBrowse link
G Prmt3 protein arginine methyltransferase 3 IEP mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr 1:99,492,712...99,581,774
Ensembl chr 1:99,492,724...99,579,435
JBrowse link
G Prmt5 protein arginine methyltransferase 5 IEP mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chr15:27,968,893...27,978,291
Ensembl chr15:27,968,910...27,978,296
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:26381519 RGD:11099992 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133
JBrowse link
G Pten phosphatase and tensin homolog ISO CTD Direct Evidence: therapeutic CTD PMID:17982072 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptgdr prostaglandin D2 receptor susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr15:17,360,304...17,367,679
Ensembl chr15:17,360,304...17,367,679
JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 ISO Aspirin exacerbated asthma
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:27103662 PMID:19796209 PMID:19392992 PMID:18757520 RGD:5135020, RGD:5135019, RGD:5135018 NCBI chr 1:207,585,088...207,590,275
Ensembl chr 1:207,587,917...207,589,213
JBrowse link
G Ptger3 prostaglandin E receptor 3 treatment IMP RGD PMID:23221044 RGD:10043366 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 susceptibility
severity
ISO
IEP
mRNA:increased expression:lung
DNA:SNP: :8473T>C (human)
mRNA, protein:increased expression:lung:
DNA:SNP: :rs689465 (human)
RGD PMID:19878559 PMID:15316498 PMID:17573729 PMID:18097056 PMID:18489027 More... RGD:5135514, RGD:5143931, RGD:5143923, RGD:5135534, RGD:5135526, RGD:5135522, RGD:5135515 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rad50 RAD50 double strand break repair protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396
JBrowse link
G Rhoa ras homolog family member A IEP RGD PMID:18391481 RGD:2298885 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rnase3 ribonuclease A family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8874658 PMID:12153692 PMID:12587966 NCBI chr15:24,511,894...24,512,764
Ensembl chr15:24,511,891...24,512,790
JBrowse link
G RT1-A1 RT1 class Ia, locus A1 susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr20:4,905,309...4,914,593 JBrowse link
G RT1-B RT1 class II, locus B susceptibility ISO DNA:polymorphisms: : RGD PMID:21814517 RGD:13506911
G RT1-Ba RT1 class II, locus Ba ISO DNA:polymorphisms (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism (human)
CTD
RGD
PMID:10792356 PMID:12890388 PMID:10051703 PMID:11802952 PMID:19052351 RGD:5147799, RGD:1331670, RGD:5147831, RGD:5147617 NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744
JBrowse link
G RT1-Bb RT1 class II, locus Bb susceptibility
disease_progression
no_association
ISO Alternaria sensitive asthma
DNA:polymorphisms: :
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms (human)
CTD
RGD
PMID:10792356 PMID:20298583 PMID:20159242 PMID:20214848 PMID:23331206 More... RGD:4144113, RGD:13506913, RGD:4144181, RGD:13506906, RGD:5147831, RGD:5147799, RGD:5147617 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
JBrowse link
G RT1-Da RT1 class II, locus Da susceptibility ISO DNA:polymorphisms: : RGD PMID:20159242 RGD:13506913 NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 susceptibility
no_association
severity
ISO DNA:polymorphisms: :
CTD Direct Evidence: marker/mechanism
DNA:polymorphism (human)
CTD
RGD
PMID:16792590 PMID:19528258 PMID:20159242 PMID:23331206 PMID:10051703 More... RGD:4144196, RGD:13506913, RGD:13506906, RGD:1331670, RGD:5147663, RGD:5147607, RGD:4144181 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G RT1-Ha RT1 class II, locus Ha susceptibility ISO DNA:polymorphism: : RGD PMID:21814517 RGD:13506911 NCBI chr20:4,760,631...4,770,662
Ensembl chr20:4,760,118...4,770,244
JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 susceptibility ISO CTD Direct Evidence: marker/mechanism CTD
OMIM
RGD
PMID:15611928 RGD:5144118 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
G Runx1 RUNX family transcription factor 1 ISO DNA:SNPs: :multiple RGD PMID:21803869 RGD:6482835 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542
JBrowse link
G Runx3 RUNX family transcription factor 3 ISS OMIM:600807 MouseDO NCBI chr 5:147,393,926...147,419,161
Ensembl chr 5:147,360,994...147,419,156
JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 susceptibility IEP
ISO
mRNA,protein:decreased expression:bronchial alveolar lavage fluid, lung:
ClinVar Annotator: match by term: Asthma, susceptibility to
associated with allergic rhinitis; DNA:SNP:exon:38G>A (human)
protein:decreased expression:serum
ClinVar
RGD
PMID:9550363 PMID:12921604 PMID:21255142 PMID:15467329 RGD:5144052, RGD:5144226, RGD:5144148 NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610
JBrowse link
G Scgb3a2 secretoglobin, family 3A, member 2 susceptibility
severity
no_association
ISO DNA:SNP:promoter:-112G>A (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Asthma, susceptibility to
mRNA,protein:decreased expression:;lung
protein:increased expression:sputum
CTD
OMIM
ClinVar
RGD
PMID:11813133 PMID:11813133 PMID:15531759 PMID:16456148 PMID:17218572 More... RGD:5144229, RGD:5128690, RGD:5144233, RGD:5144232, RGD:5144231, RGD:5144230 NCBI chr18:35,932,840...35,935,762
Ensembl chr18:35,932,840...35,935,762
JBrowse link
G Sell selectin L ISO RGD PMID:21437035 PMID:21515793 RGD:5685685, RGD:5685696 NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456
JBrowse link
G Serpina1 serpin family A member 1 IEP Fisher rats, shown to exhibit hyperactive airway responses at 14 days of age, had higher transcript and protein levels of Serpina1 than same age Brown Norway rats. RGD PMID:20118217 RGD:5131869 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
JBrowse link
G Serpine1 serpin family E member 1 susceptibility
no_association
severity
IEP
ISO
protein:increased activity, increased expression:plasma, lung
DNA:polymorphism:promoter:rs1799768 (human)
protein:increased expression:plasma
RGD PMID:18594148 PMID:19063817 PMID:19604112 PMID:19703828 RGD:4144836, RGD:4144832, RGD:4144833, RGD:4144831 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sftpa1 surfactant protein A1 IEP
ISO
protein:decreased expression:lung, Clara cell, pneumocyte
mRNA, protein:increased expression:lung
RGD PMID:15816355 PMID:16629790 PMID:18802356 PMID:18926058 RGD:4143398, RGD:4143462, RGD:4143516, RGD:4143289 NCBI chr16:17,008,180...17,011,686
Ensembl chr16:17,008,180...17,011,685
JBrowse link
G Sftpb surfactant protein B ISO
IEP
protein:increased expression:lung
mRNA, protein:decreased expression:lung
protein:decreased expression:lung, Clara cell
RGD PMID:16629790 PMID:11472974 PMID:18926058 PMID:15816355 RGD:4143462, RGD:4143465, RGD:4143289, RGD:4143398 NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436
JBrowse link
G Sftpc surfactant protein C susceptibility ISO mRNA, protein:decreased expression:lung
protein:increased expression:lung
DNA:polymorphism: :p.A53T (human)
RGD PMID:11472974 PMID:16629790 PMID:19910179 RGD:4143465, RGD:4143462, RGD:4144063 NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777
JBrowse link
G Sftpd surfactant protein D ISO
IEP
protein:increased expression:lung
associated with Bronchitis;protein:increased expression:lung
mRNA, protein:increased expression:lung
RGD PMID:16629790 PMID:11472974 PMID:18266831 PMID:16839409 PMID:18802356 RGD:4143462, RGD:4143465, RGD:4143517, RGD:4143508, RGD:4143516 NCBI chr16:17,046,491...17,058,968
Ensembl chr16:17,046,483...17,059,927
JBrowse link
G Slc11a1 solute carrier family 11 member 1 ISO RGD PMID:12847242 RGD:5684966 NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101
JBrowse link
G Slc18a3 solute carrier family 18 member A3 IEP RGD PMID:17328924 RGD:5686690 NCBI chr16:7,713,630...7,716,491 JBrowse link
G Slc22a1 solute carrier family 22 member 1 IEP RGD PMID:17328924 RGD:5686690 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc5a7 solute carrier family 5 member 7 IEP mRNA:decreased expression:lung RGD PMID:17328924 RGD:5686690 NCBI chr 9:7,595,440...7,626,258
Ensembl chr 9:7,595,444...7,626,258
JBrowse link
G Slc6a4 solute carrier family 6 member 4 susceptibility ISO DNA:repeat:intron (human) RGD PMID:19806585 RGD:4889460 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22867017 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 ISO RGD PMID:15743779 RGD:1581231 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sprr2b small proline rich protein 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 2:177,852,824...177,853,096
Ensembl chr 2:177,852,824...177,853,096
JBrowse link
G Stat4 signal transducer and activator of transcription 4 treatment IEP RGD PMID:18211752 RGD:2317290 NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Stat6 signal transducer and activator of transcription 6 treatment IEP
IDA
RGD PMID:19087723 PMID:16083555 RGD:7244151, RGD:7244153 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
JBrowse link
G Tac1 tachykinin, precursor 1 ISO protein:increased expression:lung RGD PMID:11031342 RGD:5147836 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Tacr1 tachykinin receptor 1 IEP
ISO
protein:increased expression:lung
mRNA:increased expression:lung
mRNA,protein:increased expression:lung
RGD PMID:17392578 PMID:8240667 PMID:16409782 RGD:2304339, RGD:5147645, RGD:5147475 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733
JBrowse link
G Tacr2 tachykinin receptor 2 ISO DNA:SNP:cds:p.G231E (human) RGD PMID:20175803 PMID:19880429 RGD:5147640, RGD:5147641 NCBI chr20:30,208,907...30,223,446
Ensembl chr20:30,208,907...30,223,446
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member susceptibility ISO DNA:polymorphism: : RGD PMID:12640628 RGD:5147845 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901
JBrowse link
G Tbx21 T-box transcription factor 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15806396 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831
JBrowse link
G Tbxa2r thromboxane A2 receptor susceptibility
severity
ISO DNA:polymorphism:cds:924T>C(human) GAD
RGD
PMID:15118671 PMID:12000493 PMID:15805995 RGD:1331525, RGD:11059535, RGD:11059534 NCBI chr 7:8,383,347...8,390,753
Ensembl chr 7:8,383,378...8,388,176
JBrowse link
G Tgfb1 transforming growth factor, beta 1 onset
no_association
ISO
IEP
DNA:SNP: :-509C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs:promoter, exon:multiple (human)
DNA:SNP:cds:915G>C (human)
mRNA:increased expression:lung
protein:increased expression:serum
DNA:polymorphisms: :multiple (human)
DNA:polymorphism: :-509C>T (human)
CTD
RGD
PMID:16365456 PMID:19138248 PMID:17673695 PMID:18366906 PMID:19096005 More... RGD:4145295, RGD:4145280, RGD:4145143, RGD:4145132, RGD:4145142, RGD:4145113, RGD:4145139, RGD:4145144, RGD:4143443, RGD:4145299, RGD:4145297 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Thbd thrombomodulin ISO RGD PMID:20709825 RGD:5684984 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16926187 NCBI chr 7:17,520,827...17,571,871
Ensembl chr 7:17,521,919...17,571,839
JBrowse link
G Tlr1 toll-like receptor 1 susceptibility ISO DNA:SNP (human) RGD PMID:18547625 RGD:4889528 NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125
JBrowse link
G Tlr10 toll-like receptor 10 susceptibility ISO DNA:SNP (human) RGD PMID:18547625 RGD:4889528 NCBI chr14:43,400,843...43,414,056
Ensembl chr14:43,406,217...43,413,917
JBrowse link
G Tlr2 toll-like receptor 2 susceptibility
severity
ISO DNA:SNP: :596T>C (human)
DNA:polymorphism:cds:p.R753Q(human)
DNA:SNP: :rs3804100 (human)
DNA:SNP: :rs7656411 (human)
DNA:SNP: :rs4696480 (human)
RGD PMID:19096003 PMID:22402138 PMID:19148143 PMID:18202345 PMID:20815312 More... RGD:4144228, RGD:7800732, RGD:2312679, RGD:4145343, RGD:4145352, RGD:4144171, RGD:4145334 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tlr3 toll-like receptor 3 no_association ISO
IMP
Asthma, Virus-Induced; mRNA:increased expression:sputum (human)
DNA:snp:cds:p.L412F (human)
RGD PMID:21129050 PMID:17434873 PMID:14987294 PMID:17610940 PMID:21364926 RGD:5129226, RGD:5129478, RGD:5129493, RGD:5129475, RGD:5128500 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
JBrowse link
G Tlr4 toll-like receptor 4 susceptibility
no_association
severity
ISO DNA:Polymorphism:cds:p.D299G (human)
DNA:SNPs::
protein:decreased expression:leukocytes, mononuclear
DNA:SNPs: :rs10983755, rs1927914 (human)
DNA:polymorphisms:cds:c.896A>G, 1196C>T (human)
RGD PMID:15356557 PMID:20628601 PMID:20685742 PMID:19067129 PMID:19330007 More... RGD:4144817, RGD:4144176, RGD:4144171, RGD:4144190, RGD:4144141, RGD:4144188, RGD:4144198 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr6 toll-like receptor 6 susceptibility ISO DNA:SNP (human)
DNA:SNP: :p.S249P (human)
RGD PMID:18547625 PMID:15266299 RGD:4889528, RGD:4889538 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685
JBrowse link
G Tlr9 toll-like receptor 9 no_association
susceptibility
severity
ISO DNA:SNP:promoter:g.-1237T>C rs5743836 (human)
DNA:snp:promoter:g.-1237T>C rs5743836 (human)
protein:increased expression:peripheral blood mononuclear cell (human)
RGD PMID:21324137 PMID:18312481 PMID:20016192 PMID:20072849 RGD:5130712, RGD:4144208, RGD:5129104, RGD:4889523 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
JBrowse link
G Tnc tenascin C ISO CTD Direct Evidence: marker/mechanism
DNA:SNPs: :multiple (human)
protein:increased expression:bronchus basement membrane
DNA:SNP:exon:p.L1677I (human)
CTD
RGD
PMID:16115819 PMID:17125141 PMID:18305139 PMID:9310019 PMID:16115819 RGD:4889565, RGD:4889589, RGD:4889572, RGD:4889569 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
JBrowse link
G Tnf tumor necrosis factor susceptibility
no_association
ISO DNA:polymorphism:promoter: c. -308A>G (human)
ClinVar Annotator: match by term: ASTHMA, BRONCHIAL
CTD Direct Evidence: marker/mechanism
associated with obesity; DNA:polymorphism:promoter
DNA:polymorphisms:: rs1799964, rs1799724 (human)
DNA:polymorphisms: :
associated with nasal polys; protein:increased expression:nose
DNA:polymorphism:promoter:c.-863C > A (human)
ClinVar
OMIM
CTD
RGD
PMID:8056188 PMID:9818939 PMID:10450718 PMID:11261930 PMID:11506397 More... RGD:4143443, RGD:4143238, RGD:4145508, RGD:4143254, RGD:4143240, RGD:4142802, RGD:4143369, RGD:4143372 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO protein:increased expression:lung (mouse) RGD PMID:20484920 RGD:5131201 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24453940 NCBI chr10:39,037,048...39,084,328
Ensembl chr10:39,037,058...39,077,625
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 severity ISO
IMP
CTD Direct Evidence: marker/mechanism
ovalbumin sensitization
CTD
RGD
PMID:19458046 PMID:31969645 RGD:127285811 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570
JBrowse link
G Trpa1em1Gne transient receptor potential cation channel, subfamily A, member 1;CRISPR/Cas9 induced mutant 1, Gne severity IMP ovalbumin sensitization RGD PMID:31969645 RGD:127285811
G Tslp thymic stromal lymphopoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21804549 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548
JBrowse link
G Ucn urocortin IEP associated with Hypersensitivity;mRNA, protein:increased expression:lung RGD PMID:16427607 RGD:1642781 NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950
JBrowse link
G Uts2 urotensin 2 IEP RGD PMID:17045018 RGD:2306832 NCBI chr 5:161,450,846...161,456,235
Ensembl chr 5:161,450,846...161,456,237
JBrowse link
G Vdr vitamin D receptor no_association ISO DNA:SNP: :rs7975232 (human)
DNA:SNP (human)
DNA:SNPs: :multiple (human)
DNA:SNPs (human)
RGD PMID:19622139 PMID:21103062 PMID:15282200 PMID:20124605 RGD:4889868, RGD:4889866, RGD:4889854, RGD:4889867 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
G Vegfa vascular endothelial growth factor A ISO protein:increased expression:sputum
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:11907124 PMID:15201500 PMID:19263519 PMID:19178538 RGD:6892723 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vip vasoactive intestinal peptide IDA
ISO
RGD PMID:21419198 PMID:16782752 RGD:5685381, RGD:5685620 NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216
JBrowse link
G Wdr36 WD repeat domain 36 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chr18:24,473,645...24,501,773
Ensembl chr18:24,473,663...24,508,092
JBrowse link
Asthma and Nasal Polyps term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-Da RT1 class II, locus Da susceptibility ISO DNA:SNPs,haplotype:introns: RGD PMID:22391069 RGD:13506908 NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
JBrowse link
G Tbx21 T-box transcription factor 21 ISO ClinVar Annotator: match by term: Asthma and nasal polyps ClinVar PMID:15806396 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831
JBrowse link
asthma, nasal polyps, and aspirin intolerance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox15 arachidonate 15-lipoxygenase ISO ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance ClinVar PMID:17959182 PMID:21558275 PMID:30643255 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
JBrowse link
G Ptger2 prostaglandin E receptor 2 ISO OMIM NCBI chr15:18,215,013...18,228,714
Ensembl chr15:18,217,285...18,228,714
JBrowse link
G Tbx21 T-box transcription factor 21 ISO ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance OMIM
ClinVar
PMID:25741868 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831
JBrowse link
atopic dermatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actl9 actin-like 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23042114 NCBI chr 7:14,234,504...14,235,881
Ensembl chr 7:14,234,504...14,235,881
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 ISS OMIM:603165 MouseDO NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27869817 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Apoe apolipoprotein E ISO protein:decreased expression:plasma RGD PMID:19116453 RGD:11040546 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Artn artemin ISO CTD Direct Evidence: marker/mechanism CTD PMID:27869817 NCBI chr 5:131,458,596...131,470,193
Ensembl chr 5:131,464,756...131,468,025
JBrowse link
G Bdnf brain-derived neurotrophic factor susceptibility
no_association
ISO DNA:polymorphism::C270T(human)
protein:increased expression:serum:
DNA:polymorphism:cds:p.V66M(human)
mRNA:decreased expression:mast cell
RGD PMID:19522715 PMID:17073871 PMID:19038326 PMID:17845420 RGD:8657028, RGD:8657069, RGD:8657067, RGD:8657065 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G C3 complement C3 ISO protein:increased expression:plasma RGD PMID:3923750 RGD:7401273 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Card11 caspase recruitment domain family, member 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23042114 PMID:28628108 NCBI chr12:13,620,979...13,758,115
Ensembl chr12:13,621,087...13,758,112
JBrowse link
G Casp8 caspase 8 ISS OMIM:603165 MouseDO NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Ccdc80 coiled-coil domain containing 80 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23042114 NCBI chr11:55,685,165...55,718,827
Ensembl chr11:55,685,872...55,719,137
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr19:10,202,317...10,203,768
Ensembl chr19:10,202,128...10,203,819
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 severity
treatment
ISO protein:increased expression:plasma RGD PMID:11133838 PMID:19162238 RGD:7483580, RGD:7483583 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 PMID:22125604 NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400
JBrowse link
G Ccl24 C-C motif chemokine ligand 24 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr12:21,100,835...21,104,832
Ensembl chr12:21,100,835...21,104,893
JBrowse link
G Ccl26 C-C motif chemokine ligand 26 ISO protein:increased expression:serum (human) RGD PMID:14616792 RGD:11087554 NCBI chr12:21,109,384...21,114,336
Ensembl chr12:21,109,421...21,114,335
JBrowse link
G Ccl27 C-C motif chemokine ligand 27 ISO RGD PMID:12642842 RGD:1626250 NCBI chr 5:56,941,402...56,948,511
Ensembl chr 5:56,941,402...56,948,506
JBrowse link
G Ccl28 C-C motif chemokine ligand 28 severity ISO associated with Asthma; protein: increased secretion:serum (human) RGD PMID:20161852 RGD:4892193 NCBI chr 2:51,601,354...51,625,999
Ensembl chr 2:51,601,331...51,625,997
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO protein:increased expression:skin,monocyte: RGD PMID:15370700 RGD:8661734 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO protein:increased expression:skin
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:18249437 PMID:16449815 RGD:6893391 NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18249437 PMID:16449815 RGD:6893391 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Cd40 CD40 molecule ISO RGD PMID:18693155 RGD:5132274 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cdsn corneodesmosin ISO protein:decreased expression:skin of body (human) RGD PMID:21211653 RGD:42721970 NCBI chr20:3,179,432...3,185,854
Ensembl chr20:3,179,438...3,184,250
JBrowse link
G Cldn1 claudin 1 ISO mRNA,protein:decreased expression:epidermis; DNA:SNPs:intron,promoter :rs17501010,rs9290927,rs893051,rs9290929,rs16865373(human) RGD PMID:21163515 RGD:11344875 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
JBrowse link
G Cldn23 claudin 23 ISO mRNA:decreased expression:epidermis: RGD PMID:21163515 RGD:11344875 NCBI chr16:56,413,677...56,415,401
Ensembl chr16:56,413,381...56,415,523
JBrowse link
G Cma1 chymase 1 ISO DNA:polymorphism:5' utr:g.-1903G>A rs1800875 (human) RGD PMID:16134991 RGD:1625394 NCBI chr15:29,417,451...29,420,233
Ensembl chr15:29,417,451...29,420,233
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 susceptibility ISO DNA:SNP,haplotype:exon,3'UTR:rs3087243,rs231775 (human)
mRNA:increased expression:blood:
RGD PMID:16445777 PMID:22357516 RGD:7411698, RGD:7411700 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
JBrowse link
G Ctse cathepsin E ISS OMIM:603165 MouseDO NCBI chr13:43,091,954...43,114,509
Ensembl chr13:43,092,128...43,114,502
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 ISO protein:increased expression:serum RGD PMID:15131578 RGD:9491761 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO protein:decreased expression:blood, leukocyte RGD PMID:24821910 PMID:15131578 RGD:9491393, RGD:9491761 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27869817 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp4f39 cytochrome P450, family 4, subfamily f, polypeptide 39 ISO ClinVar Annotator: match by term: Atopic eczema ClinVar PMID:25741868 NCBI chr 7:11,426,806...11,505,553
Ensembl chr 7:11,433,371...11,536,181
JBrowse link
G Dock8 dedicator of cytokinesis 8 ISO DNA:mutations:cds: RGD PMID:22476911 RGD:40903056 NCBI chr 1:222,649,309...222,842,474
Ensembl chr 1:222,649,309...222,842,474
JBrowse link
G Emsy EMSY transcriptional repressor, BRCA2 interacting ISO CTD Direct Evidence: marker/mechanism CTD PMID:23042114 NCBI chr 1:152,881,485...152,960,420
Ensembl chr 1:152,883,992...152,953,528
JBrowse link
G F2 coagulation factor II ISO protein:increased expression:plasma RGD PMID:21488867 RGD:5147756 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G Fcgr2a Fc gamma receptor 2A severity ISO protein:increased expression:eosinophil RGD PMID:7564170 PMID:19414806 RGD:5147985, RGD:5508430 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
JBrowse link
G Flg filaggrin ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Atopic eczema
CTD
ClinVar
PMID:16444271 PMID:16550169 PMID:16815158 PMID:17030239 PMID:17417636 More... NCBI chr 2:178,888,688...178,912,731 JBrowse link
G Glb1 galactosidase, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23042114 NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127
JBrowse link
G Gstm1 glutathione S-transferase mu 1 susceptibility ISO DNA:deletion: : RGD PMID:21176116 PMID:20674822 RGD:5490539, RGD:5490981 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstp1 glutathione S-transferase pi 1 susceptibility ISO DNA:polymorphism:exon:p.I105V (rs1695) (human) RGD PMID:19842992 PMID:20674822 RGD:5490540, RGD:5490981 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gstt1 glutathione S-transferase theta 1 ISO DNA:deletion, haplotype: : RGD PMID:19842992 RGD:5490540 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO RGD PMID:16159638 RGD:5128852 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Hnmt histamine N-methyltransferase ISO RGD PMID:19025430 RGD:5128889 NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012
JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18249437 PMID:22101570 RGD:8157618 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ifnl3 interferon, lambda 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22295096 NCBI chr 1:83,814,456...83,816,096
Ensembl chr 1:83,814,564...83,816,096
JBrowse link
G Il10 interleukin 10 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18249437 PMID:23843958 RGD:7364805 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il13 interleukin 13 severity
treatment
ISO DNA:SNPs: :rs3091307, rs20541 (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:4257G>A (human)
DNA, protein:SNP, increased expression:promoter, serum:-1112C>T (human)
CTD
RGD
PMID:18249437 PMID:22355542 PMID:21913997 PMID:16672002 PMID:17313488 More... RGD:5684364, RGD:8549583, RGD:8549539, RGD:8549531, RGD:8549529, RGD:8549509 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 ISO mRNA:increased expression:skin RGD PMID:14527737 RGD:8549525 NCBI chr  X:115,348,860...115,408,682
Ensembl chr  X:115,348,860...115,408,681
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 ISO protein:increased expression:serum RGD PMID:21462799 PMID:20971924 RGD:8549521, RGD:8549556 NCBI chr  X:111,002,590...111,074,053
Ensembl chr  X:111,002,592...111,072,381
JBrowse link
G Il17a interleukin 17A treatment
severity
ISO protein:increased expression:dermis, lymphocyte (human)
protein:increased expression:epidermis (mouse)
RGD PMID:24337738 PMID:18432274 PMID:22848348 RGD:8698670, RGD:9068436, RGD:9068417 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il18 interleukin 18 severity
no_association
ISO
ISS
protein:increased expression:serum
OMIM:603165
DNA:SNP:promoter:-140C>G (rs360721) (human)
DNA:SNP:promoter:-137G>C (rs187238) (human)
DNA:SNPs, haplotype: :rs795467, rs4937113, rs5744247 (human)
MouseDO
RGD
PMID:15317323 PMID:22840759 PMID:22840759 PMID:11490156 PMID:17517100 RGD:8655872, RGD:8655914, RGD:8655914, RGD:8655908, RGD:8655876 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 susceptibility ISO associated with food hypersensitivity;
protein:increased expression:CD8+ T cell:
DNA:SNP:promoter:rs2069762(human)
RGD PMID:7547077 PMID:1673687 PMID:16672002 PMID:16333313 PMID:21982597 RGD:8662961, RGD:8693325, RGD:8549583, RGD:8663473, RGD:8663444 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il21r interleukin 21 receptor ISO protein:increased expression:skin RGD PMID:19075398 PMID:19075398 RGD:6892938, RGD:6892938 NCBI chr 1:180,168,028...180,195,690
Ensembl chr 1:180,168,097...180,195,522
JBrowse link
G Il25 interleukin 25 ISO protein:increased expression:arm skin RGD PMID:23657503 RGD:39128244 NCBI chr15:28,408,842...28,411,676
Ensembl chr15:28,408,842...28,411,893
JBrowse link
G Il31 interleukin 31 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr12:33,095,108...33,105,026
Ensembl chr12:33,092,097...33,105,037
JBrowse link
G Il33 interleukin 33 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Il4 interleukin 4 ISO DNA:SNP:promoter:-590C>T (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum
CTD
RGD
PMID:11886533 PMID:12230500 PMID:18249437 PMID:9643293 PMID:8363440 RGD:7829786, RGD:7829795 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il4r interleukin 4 receptor susceptibility ISO DNA:mutation:cds:p.Q576R(human) RGD PMID:9392697 RGD:11530001 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
JBrowse link
G Il5 interleukin 5 ISO mRNA: increased expression: skin
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:11886533 PMID:18249437 PMID:22299064 RGD:5687175 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 ISO ClinVar Annotator: match by term: Atopic eczema ClinVar NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24046278 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO DNA:polymorphisms:promoter, exon: RGD PMID:20642202 RGD:8693720 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mc1r melanocortin 1 receptor ISO protein: increased expression: skin RGD PMID:19889022 RGD:5687321 NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192
JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment ISO RGD PMID:27776525 RGD:13204759 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Ms4a2 membrane spanning 4-domains A2 susceptibility ISO Atopy and bronchial hyperresponsiveness, OMIM:147050
Atopy and bronchial hyperresponsiveness, OMIM:147050 DNA:polymorphism:CDS:amino acid E237G
RGD PMID:8817330 PMID:8817330 RGD:1599903, RGD:1599903 NCBI chr 1:208,440,179...208,448,716
Ensembl chr 1:208,440,361...208,448,310
JBrowse link
G Nat2 N-acetyltransferase 2 susceptibility
no_association
ISO DNA:polymorphisms: :481C>T, 590G>A(human)
DNA:polymorphisms: :481C>T,590G>A,857G>A(human)
RGD PMID:16224574 PMID:14528063 RGD:8552664, RGD:8552668 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Nfkbia NFKB inhibitor alpha ISS OMIM:603165 MouseDO NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbiz NFKB inhibitor zeta ISS OMIM:603165 MouseDO NCBI chr11:44,782,676...44,810,723
Ensembl chr11:44,782,676...44,810,723
JBrowse link
G Ngf nerve growth factor ISO protein:increased expression:serum: RGD PMID:17073871 RGD:8657069 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Ngfr nerve growth factor receptor ISO protein:increased expression:nerve fibers of the papillary dermis (human) RGD PMID:16586073 RGD:5508452 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 ISO protein:increased expression:eosinophil RGD PMID:18647313 PMID:17223862 RGD:5144116, RGD:5684771 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
JBrowse link
G Ovol1 ovo like transcriptional repressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23042114 NCBI chr 1:202,855,261...202,868,858
Ensembl chr 1:202,855,265...202,866,831
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO potential therapeutic target with or without glucocorticoid therapy (mouse)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:18249437 PMID:21633371 RGD:5509940 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppia peptidylprolyl isomerase A ISO mRNA:increased expression:zone of skin (human) RGD PMID:32496587 RGD:150383342 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit ISO
ISS
OMIM:603165 MouseDO
RGD
PMID:10940923 RGD:7777149 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
JBrowse link
G S100a8 S100 calcium binding protein A8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18336422 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
JBrowse link
G Sele selectin E ISO CTD Direct Evidence: marker/mechanism CTD PMID:12410700 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Selp selectin P ISO atopy and bronchial hyperresponsiveness, OMIM:147050 RGD PMID:12929084 RGD:1599904 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845
JBrowse link
G Sharpin SHANK-associated RH domain interactor ISS OMIM:603165 MouseDO NCBI chr 7:108,070,681...108,075,012
Ensembl chr 7:108,070,687...108,074,955
JBrowse link
G Slc11a1 solute carrier family 11 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16597321 NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101
JBrowse link
G Stat6 signal transducer and activator of transcription 6 ISO CTD Direct Evidence: therapeutic CTD PMID:15306842 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO GAD
RGD
PMID:15118671 PMID:11496247 RGD:1331525, RGD:7394812 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tlr2 toll-like receptor 2 severity ISO DNA:polymorphism: :-16934A>T(human)
DNA:polymorphism:cds:p.R753Q(human)
RGD PMID:19627277 PMID:22032785 PMID:17531301 RGD:8552997, RGD:8553048, RGD:8552999 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tlr4 toll-like receptor 4 ISO DNA:polymorphism: :896G>A(human)
mRNA:increased expression:blood cell:
RGD PMID:23821954 PMID:19764566 RGD:7794689, RGD:7794745 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tmem79 transmembrane protein 79 ISS OMIM:603165 MouseDO NCBI chr 2:173,798,267...173,803,151
Ensembl chr 2:173,798,267...173,803,046
JBrowse link
G Tnf tumor necrosis factor susceptibility ISO DNA:haplotype:promoter:−308G>A,-238G>A(human) RGD PMID:22533231 RGD:7401246 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 ISO mRNA:altered expression:fibroblast RGD PMID:16650051 RGD:7777183 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
JBrowse link
G Traf3ip2 Traf3 interacting protein 2 ISS OMIM:603165 MouseDO NCBI chr20:43,011,405...43,054,654
Ensembl chr20:43,011,450...43,054,667
JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 ISS OMIM:603165 MouseDO NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296
JBrowse link
G Tslp thymic stromal lymphopoietin treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16880407 PMID:22355542 PMID:23688403 PMID:27869817 PMID:29310423 RGD:38549374 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548
JBrowse link
G Vdr vitamin D receptor severity
no_association
ISO DNA:SNPs, haplotype: :rs731236, rs1544410, rs7975232 (human)
DNA:SNP: :rs2228570 (human)
RGD PMID:23034014 PMID:23034014 RGD:8157625, RGD:8157625 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
G Vnn1 vanin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19322213 NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
JBrowse link
G Wasl WASP like actin nucleation promoting factor ISS OMIM:603165 MouseDO NCBI chr 4:53,083,536...53,132,061
Ensembl chr 4:53,083,536...53,132,022
JBrowse link
atopic dermatitis 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flg filaggrin susceptibility ISO ClinVar Annotator: match by term: Atopic dermatitis 2 | ClinVar Annotator: match by term: Dermatitis, atopic, 2, susceptibility to
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:16444271 PMID:16550169 PMID:16815158 PMID:17030239 PMID:17291859 More... NCBI chr 2:178,888,688...178,912,731 JBrowse link
atopic dermatitis 4 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Socs3 suppressor of cytokine signaling 3 susceptibility ISO OMIM NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
berylliosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:10194187 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Btnl2 butyrophilin-like 2 susceptibility ISO DNA:SNP: :rs3117099(human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:17927685 PMID:17927685 RGD:9685029 NCBI chr20:4,490,904...4,502,557
Ensembl chr20:4,489,517...4,503,341
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 disease_progression ISO DNA:polymorphisms:5' utr:multiple (human) RGD PMID:20075058 RGD:4892065 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Cd28 Cd28 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:12952926 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:16766924 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Hmox1 heme oxygenase 1 ISO protein:increased activity:sputum RGD PMID:19453654 RGD:4145349 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:8977230 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8428540 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16272364 PMID:17927685 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G Tgfb1 transforming growth factor, beta 1 severity ISO DNA:polymorphisms: :-509C>T (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:15750822 PMID:17785866 PMID:17785866 RGD:4145294 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:8428540 PMID:12449171 PMID:15127972 PMID:16980557 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
bird fancier's lung term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Muc1 mucin 1, cell surface associated ISO protein:increased expression:serum RGD PMID:15881280 RGD:5131172 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
childhood-onset asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfkbia NFKB inhibitor alpha exacerbates ISO associated with respiratory syncytial virus infectious disease;DNA:SNPs:protomer: (rs2233409) (human) RGD PMID:23487427 RGD:40902982 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
egg allergy term browser