Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:allergic disease
go back to main search page
Accession:DOID:1205 term browser browse the term
Definition:An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods. (DO)
Synonyms:exact_synonym: Allergic Reaction;   Allergies;   Allergy;   Hypersensitivities;   allergic hypersensitivity disease;   allergic reactions;   hypersensitivity;   hypersensitivity reaction type I disease
 primary_id: MESH:D006967
 xref: ICD10CM:T78.40;   NCI:C3114
For additional species annotation, visit the Alliance of Genome Resources.

show annotations for term's descendants           Sort by:
 
allergic disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcf1 ATP binding cassette subfamily F member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr20:3,309,914...3,322,828
Ensembl chr20:3,309,899...3,322,825 		JBrowse link
G Ace angiotensin I converting enzyme susceptibility ISO DNA:deletion:intron:IVS16+1464-1751del (human) RGD PMID:10200023 RGD:8142344 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822 		JBrowse link
G Agt angiotensinogen susceptibility ISO DNA:polymorphism: :p.M235T (human) RGD PMID:10200023 RGD:8142344 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B IDA associated with Diabetes Mellitus, Experimental RGD PMID:16979157 RGD:1626088 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956 		JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:8431628 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863 		JBrowse link
G Bcl2a1 BCL2-related protein A1 ISO RGD PMID:11733571 RGD:734640 NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483 		JBrowse link
G Casp1 caspase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575 		JBrowse link
G Ccl12 chemokine (C-C motif) ligand 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr10:69,476,866...69,478,416
Ensembl chr10:69,476,775...69,478,462 		JBrowse link
G Ccl17 C-C motif chemokine ligand 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr19:10,619,220...10,620,671
Ensembl chr19:10,619,220...10,620,671 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 5:58,181,025...58,182,969
Ensembl chr 5:58,181,026...58,183,017 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15585374 PMID:21625544 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001 		JBrowse link
G Ccl24 C-C motif chemokine ligand 24 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr12:24,131,529...24,152,626
Ensembl chr12:24,148,567...24,152,625 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15585374 PMID:23624239 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15585374 PMID:21625544 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544
G Ccr6 C-C motif chemokine receptor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 1:53,063,380...53,087,519
Ensembl chr 1:53,065,025...53,087,474 		JBrowse link
G Ccr9 C-C motif chemokine receptor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 8:132,827,325...132,842,130
Ensembl chr 8:132,828,091...132,842,130 		JBrowse link
G Cd14 CD14 molecule resistance ISO DNA:polymorphism:promoter:c. -159C>T (human) RGD PMID:19222419 RGD:4144798 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153 		JBrowse link
G Cd274 CD274 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:20488241 PMID:23624239 NCBI chr 1:247,519,890...247,539,659
Ensembl chr 1:247,519,939...247,537,943 		JBrowse link
G Cd40lg CD40 ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562 		JBrowse link
G Clec4a3 C-type lectin domain family 4, member A3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23624239 NCBI chr 4:155,913,366...155,923,079
Ensembl chr 4:155,913,366...155,923,079 		JBrowse link
G Commd1 copper metabolism domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22216203 NCBI chr14:107,664,321...107,759,974
Ensembl chr14:107,664,255...107,760,191 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr  X:71,614,346...71,616,997
Ensembl chr  X:71,614,346...71,616,997 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19022366 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147 		JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 severity ISO DNA:SNP: :927T>C (human) RGD PMID:16776674 RGD:4782072 NCBI chr  X:77,671,028...77,700,491
Ensembl chr  X:77,674,150...77,700,269 		JBrowse link
G Dsg1 desmoglein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23974871 NCBI chr18:12,008,301...12,040,337
Ensembl chr18:12,008,759...12,038,053 		JBrowse link
G Fcgr3a Fc fragment of IgG receptor IIIa treatment ISO associated with Purpura, Thrombocytopenic, Idiopathic RGD PMID:22025730 RGD:11352264 NCBI chr13:89,385,775...89,396,047
Ensembl chr13:89,385,859...89,396,051 		JBrowse link
G Foxp3 forkhead box P3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27965764 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 susceptibility ISO DNA:deletion: : RGD PMID:16580705 RGD:5490996 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 susceptibility ISO DNA:polymorphism:exon:p.I105V (rs1695) (human) RGD PMID:20526719 RGD:5133266 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147 		JBrowse link
G Hp haptoglobin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16597321 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO associated with Giardiasis;protein:increased expression:serum RGD PMID:7524984, PMID:15587302 RGD:8158114, RGD:8547689 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:10886234 PMID:21625544 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Il13 interleukin 13 ISO DNA:SNP:promoter, 3' utr:-1055C>T, 4738G>A (human)
CTD Direct Evidence: marker/mechanism		 CTD PMID:21625544, PMID:11588017 RGD:4765128 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466 		JBrowse link
G Il16 interleukin 16 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23624239 NCBI chr 1:145,781,923...145,881,538
Ensembl chr 1:145,781,928...145,870,912 		JBrowse link
G Il17a interleukin 17A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786 		JBrowse link
G Il18 interleukin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299 		JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 9:46,840,646...46,881,241
Ensembl chr 9:46,840,992...46,881,264 		JBrowse link
G Il2 interleukin 2 ISO RGD PMID:21509781 RGD:5147912 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854 		JBrowse link
G Il2rb interleukin 2 receptor subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 7:119,701,338...119,716,238
Ensembl chr 7:119,701,251...119,716,238 		JBrowse link
G Il4 interleukin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16095146 PMID:21625544 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531 		JBrowse link
G Il5ra interleukin 5 receptor subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 4:138,796,165...138,834,164
Ensembl chr 4:138,795,327...138,830,117 		JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944 		JBrowse link
G Itgb2 integrin subunit beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647 		JBrowse link
G Kng2 kininogen 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11160071 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Lta lymphotoxin alpha ISO DNA:polymorphism, haplotype
associated with Nasal Polyps		 RGD PMID:11591192, PMID:22545387 RGD:8548785, RGD:8548802 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 ISO CTD Direct Evidence: therapeutic CTD PMID:21544193 NCBI chr10:98,707,160...98,823,054
Ensembl chr10:98,706,960...98,823,287 		JBrowse link
G Mif macrophage migration inhibitory factor ISO DNA:polymorphisms:promoter: RGD PMID:14962818 RGD:4891046 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16766537 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910 		JBrowse link
G Mylk myosin light chain kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15621374 NCBI chr11:69,013,060...69,260,039
Ensembl chr11:69,013,050...69,223,158 		JBrowse link
G Pf4 platelet factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr14:18,848,549...18,849,258
Ensembl chr14:18,848,549...18,849,258 		JBrowse link
G Ppbp pro-platelet basic protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:23624239 NCBI chr14:18,852,433...18,853,237
Ensembl chr14:18,851,954...18,853,315 		JBrowse link
G RT1-Ba RT1 class II, locus Ba susceptibility ISO DNA:polymorphism (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms (human)		 CTD PMID:8725357, PMID:15853900, PMID:10202362, PMID:16112029 RGD:5147651, RGD:5147866, RGD:5147826 NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721 		JBrowse link
G RT1-Bb RT1 class II, locus Bb susceptibility ISO DNA:polymorphism (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms (human)		 CTD PMID:8725357, PMID:20684489, PMID:10202362, PMID:16112029, PMID:10689122, PMID:15853900 RGD:5147606, RGD:5147866, RGD:5147826, RGD:5147814, RGD:5147651 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711 		JBrowse link
G RT1-Da RT1 class II, locus Da ISO RGD PMID:9104792 RGD:5490205 NCBI chr20:4,127,644...4,132,616
Ensembl chr20:4,127,644...4,132,616 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 susceptibility ISO DNA:polymorphism (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms (human)		 CTD PMID:8725357, PMID:15853900, PMID:16112029, PMID:10689122 RGD:5147651, RGD:5147826, RGD:5147814 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190 		JBrowse link
G Selp selectin P ISO CTD Direct Evidence: marker/mechanism CTD PMID:12929084 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901 		JBrowse link
G Tac1 tachykinin, precursor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11160071 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819 		JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member ISO DNA:polymorphism, haplotype: :p.V333I (human) RGD PMID:11591192 RGD:8548785 NCBI chr20:3,979,302...3,989,669
Ensembl chr20:3,979,035...3,989,669 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19138248 PMID:21625544 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16095146 PMID:21625544 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299 		JBrowse link
Acquired Angioedema term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F12 coagulation factor XII disease_progression ISO RGD PMID:9129025 RGD:11565081 NCBI chr17:9,736,577...9,744,420
Ensembl chr17:9,736,577...9,744,420 		JBrowse link
G F2 coagulation factor II disease_progression ISO protein:increased expression:plasma: RGD PMID:9129025 RGD:11565081 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031 		JBrowse link
G F7 coagulation factor VII disease_progression ISO RGD PMID:9129025 RGD:11565081 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945 		JBrowse link
G Kng2 kininogen 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9734886 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Serping1 serpin family G member 1 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:9734886 PMID:23406939 NCBI chr 3:72,161,230...72,171,109
Ensembl chr 3:72,161,189...72,171,078 		JBrowse link
allergic asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl26 C-C motif chemokine ligand 26 treatment ISO RGD PMID:25530546 RGD:11081163 NCBI chr12:24,157,182...24,161,870
Ensembl chr12:24,158,766...24,161,869 		JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 treatment ISO RGD PMID:23933317 RGD:40903070 NCBI chr  X:77,671,028...77,700,491
Ensembl chr  X:77,674,150...77,700,269 		JBrowse link
G Epx eosinophil peroxidase ISO protein:increased expression:urine: RGD PMID:11846868 RGD:13506893 NCBI chr10:75,160,690...75,171,774
Ensembl chr10:75,160,690...75,171,774 		JBrowse link
G Il25 interleukin 25 treatment ISO RGD PMID:17889290 RGD:40902975 NCBI chr15:33,594,852...33,599,692
Ensembl chr15:33,596,301...33,599,685 		JBrowse link
G RT1-B RT1 class II, locus B susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910
G RT1-Db1 RT1 class II, locus Db1 susceptibility ISO RGD PMID:22397267 RGD:13506905 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190 		JBrowse link
G RT1-Ha RT1 class II, locus Ha susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr20:3,875,478...3,885,140
Ensembl chr20:3,875,706...3,881,461 		JBrowse link
allergic bronchopulmonary aspergillosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl17 C-C motif chemokine ligand 17 ISO associated with Cystic Fibrosis RGD PMID:17898016 RGD:4145612 NCBI chr19:10,619,220...10,620,671
Ensembl chr19:10,619,220...10,620,671 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ISO RGD PMID:15951834 RGD:5688155 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO RGD PMID:10946288 RGD:8661731
G Cftr CF transmembrane conductance regulator ISO DNA:mutations: : RGD PMID:11243954 RGD:4140482 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO RGD PMID:7743671 RGD:8547590 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Il1a interleukin 1 alpha ISO RGD PMID:8699818 RGD:7794730 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086 		JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO Chronic Necrotizing Pulmonary Aspergillosis; DNA:missense mutation:exon:p.R52C (human)
DNA:SNP:intron:1011G>A(human)		 RGD PMID:11474427, PMID:16487239 RGD:4889577, RGD:8693711 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962 		JBrowse link
G RT1-Bb RT1 class II, locus Bb susceptibility ISO associated with cystic fibrosis; DNA:polymorphisms: :DQB1*06:02, DQB1*02:01(human) RGD PMID:23278646 RGD:36049760 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 susceptibility ISO associated with cystic fibrosis; DNA:polymorphisms: : RGD PMID:23278646 RGD:36049760 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190 		JBrowse link
G Tlr9 toll-like receptor 9 susceptibility ISO DNA:SNP:promoter:g.-1237T>C rs5743836 (human) RGD PMID:18275280, PMID:18936185 RGD:5130863, RGD:5130858 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171 		JBrowse link
G Tnf tumor necrosis factor ISO RGD PMID:8699818 RGD:7794730 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A susceptibility ISO DNA:snps:5' utr, exon:g.-609G>T rs4149570, g.36A>G rs767455 (human) RGD PMID:20646338 RGD:5131174 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633 		JBrowse link
allergic conjunctivitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl11 C-C motif chemokine ligand 11 IEP mRNA:increased expression:conjunctiva RGD PMID:12682842 RGD:2307196 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ISO RGD PMID:19553621 RGD:8548840 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEP mRNA:increased expression:conjunctiva RGD PMID:12682842 RGD:2307196 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 ISO protein:increased expression:conjunctiva RGD PMID:11090473 RGD:6483824 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979 		JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO RGD PMID:18658092 RGD:6893389 NCBI chr 8:133,026,539...133,040,999
Ensembl chr 8:133,029,625...133,040,997 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO RGD PMID:8766745 RGD:8547686 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Ifng interferon gamma IDA
ISO		 RGD PMID:12234900, PMID:16123425 RGD:8142386, RGD:8142391 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Il10 interleukin 10 treatment ISO protein:increased expression:tear RGD PMID:22092652, PMID:16914468, PMID:15144463, PMID:19060266 RGD:7364837, RGD:11041889, RGD:7365076, RGD:7365027 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392 		JBrowse link
G Il13 interleukin 13 ISO associated with Allergic Rhinitis;DNA:SNPs, haplotype:promoter, exon:-1112C>T (rs1800925), p.R130Q (rs20541) (human) RGD PMID:9191598, PMID:22023794 RGD:8549533, RGD:8549595 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466 		JBrowse link
G Il1b interleukin 1 beta treatment ISO RGD PMID:9326725 RGD:7401198 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO human protein in a mouse model RGD PMID:10549671 RGD:8549802 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614 		JBrowse link
G Il4r interleukin 4 receptor susceptibility ISO associated with rhinitis; DNA:SNP: : rs2107356 (human) RGD PMID:20002627 RGD:4890389 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220 		JBrowse link
G Irf1 interferon regulatory factor 1 IEP RGD PMID:14605445 RGD:5128787 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase IDA protein:increased phosphorylation:T cell RGD PMID:14507881 RGD:1600225 NCBI chr 5:147,750,976...147,779,627
Ensembl chr 5:147,750,973...147,761,983 		JBrowse link
G Muc1 mucin 1, cell surface associated severity ISO RGD PMID:17177679 RGD:7349351 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874 		JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming severity ISO RGD PMID:17177679 RGD:7349351 NCBI chr 1:214,663,929...214,693,197 JBrowse link
G Muc4 mucin 4, cell surface associated severity ISO RGD PMID:17177679, PMID:11581187 RGD:7349351, RGD:7349400 NCBI chr11:71,242,973...71,285,217
Ensembl chr11:71,243,334...71,284,939 		JBrowse link
G Pla2g2a phospholipase A2 group IIA ISO protein:increased expression:body fluid or substance RGD PMID:21042565 RGD:6482725 NCBI chr 5:157,282,650...157,285,295
Ensembl chr 5:157,282,669...157,285,328 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 treatment ISO RGD PMID:16914468 RGD:11041889 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Tlr2 toll-like receptor 2 ISO associated with Staphylococcal Infections; RGD PMID:19358332 RGD:8552826 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061 		JBrowse link
G Tlr4 toll-like receptor 4 ISO mRNA,protein:increased expression:conjunctiva: RGD PMID:21820713, PMID:16023216, PMID:21391988 RGD:7777131, RGD:7794849, RGD:7794770 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052 		JBrowse link
G Tlr9 toll-like receptor 9 ISO mRNA,protein:decreased expression:conjunctiva: RGD PMID:16023216 RGD:7794849 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171 		JBrowse link
G Tnc tenascin C ISO DNA:SNPs: :multiple (human) RGD PMID:18305139 RGD:4889589 NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671 		JBrowse link
allergic contact dermatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca6 ATP binding cassette subfamily A member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr10:98,477,716...98,546,699
Ensembl chr10:98,478,067...98,544,447 		JBrowse link
G Asrgl1 asparaginase and isoaspartyl peptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr 1:225,309,737...225,329,743
Ensembl chr 1:225,309,246...225,329,770 		JBrowse link
G Bcl2 BCL2, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bmp6 bone morphogenetic protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820 		JBrowse link
G Calcrl calcitonin receptor like receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr 3:71,747,938...71,845,487
Ensembl chr 3:71,747,956...71,845,232 		JBrowse link
G Casp8 caspase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106 		JBrowse link
G Ccl17 C-C motif chemokine ligand 17 ISO RGD PMID:15491423 RGD:1626251 NCBI chr19:10,619,220...10,620,671
Ensembl chr19:10,619,220...10,620,671 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17597826 NCBI chr 5:58,181,025...58,182,969
Ensembl chr 5:58,181,026...58,183,017 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO protein:increased expression:ear (mouse) RGD PMID:15491423 RGD:1626251 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ISO RGD PMID:18844696 RGD:5688176 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397, PMID:10899907 RGD:8661227
G Ccr3 C-C motif chemokine receptor 3 ISO RGD PMID:22075493 RGD:6892916 NCBI chr 8:133,026,539...133,040,999
Ensembl chr 8:133,029,625...133,040,997 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 IEP mRNA:increased expression:skin, lymph node (rat) RGD PMID:16977379 RGD:2325935 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614 		JBrowse link
G Cd36 CD36 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749 		JBrowse link
G Cd3d CD3d molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:17597826 NCBI chr 8:49,282,502...49,287,095
Ensembl chr 8:49,282,460...49,287,110 		JBrowse link
G Cidec cell death-inducing DFFA-like effector c ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr 4:145,377,482...145,390,497
Ensembl chr 4:145,377,431...145,390,497 		JBrowse link
G Cish cytokine inducible SH2-containing protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr 8:116,054,547...116,059,494
Ensembl chr 8:116,054,465...116,060,723 		JBrowse link
G Cntn3 contactin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17597826 NCBI chr 4:134,783,671...135,159,309
Ensembl chr 4:134,784,668...135,069,970 		JBrowse link
G Crem cAMP responsive element modulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888 		JBrowse link
G Ctsc cathepsin C ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23178550 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11312644 PMID:19022366 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147 		JBrowse link
G Emb embigin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr 2:49,682,763...49,733,475
Ensembl chr 2:49,682,754...49,732,253 		JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr11:36,075,709...36,092,495
Ensembl chr11:36,075,709...36,092,495 		JBrowse link
G F13a1 coagulation factor XIII A1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr17:28,504,650...28,680,015
Ensembl chr17:28,504,623...28,680,362 		JBrowse link
G Fgl2 fibrinogen-like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr 4:10,323,598...10,329,241
Ensembl chr 4:10,323,607...10,329,241 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 ISO mRNA:protein:skin: RGD PMID:7876550 RGD:7421586 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905 		JBrowse link
G Fyb1 FYN binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr 2:55,834,904...55,983,805
Ensembl chr 2:55,835,151...55,983,804 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603 		JBrowse link
G Ifi30 IFI30, lysosomal thiol reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17597826 NCBI chr16:20,426,566...20,430,772
Ensembl chr16:20,426,566...20,430,752 		JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:11312644 PMID:12484431 PMID:15347381 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Igsf6 immunoglobulin superfamily, member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr 1:190,997,029...191,007,503
Ensembl chr 1:190,997,029...191,007,503 		JBrowse link
G Il10 interleukin 10 treatment ISO CTD Direct Evidence: marker/mechanism CTD PMID:15347381, PMID:23760007 RGD:7364806 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392 		JBrowse link
G Il18 interleukin 18 treatment ISO mRNA:increased expression:skin
CTD Direct Evidence: marker/mechanism		 CTD PMID:27585668, PMID:9781803, PMID:12874202 RGD:8655902, RGD:8655940 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299 		JBrowse link
G Il18bp interleukin 18 binding protein treatment ISO RGD PMID:12874202 RGD:8655940 NCBI chr 1:167,091,521...167,095,727
Ensembl chr 1:167,091,522...167,093,560 		JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:23178550 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086 		JBrowse link
G Il2 interleukin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11312644 PMID:22245253 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr17:70,500,672...70,547,929
Ensembl chr17:70,499,083...70,548,071 		JBrowse link
G Il4 interleukin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12484431 PMID:21804303 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531 		JBrowse link
G Il5 interleukin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15347381 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587 		JBrowse link
G Ipcef1 interaction protein for cytohesin exchange factors 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr 1:43,563,457...43,743,424
Ensembl chr 1:43,567,842...43,638,161 		JBrowse link
G Itgam integrin subunit alpha M ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960 		JBrowse link
G Jam2 junctional adhesion molecule 2 ISO RGD PMID:16297198 RGD:7488919 NCBI chr11:24,235,310...24,285,279
Ensembl chr11:24,266,345...24,285,275 		JBrowse link
G Jam3 junctional adhesion molecule 3 ISO RGD PMID:16297198 RGD:7488919 NCBI chr 8:28,147,110...28,208,466
Ensembl chr 8:28,147,111...28,208,466 		JBrowse link
G Kdr kinase insert domain receptor ISO mRNA:protein:skin: RGD PMID:7876550 RGD:7421586 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183 		JBrowse link
G Kmo kynurenine 3-monooxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227 		JBrowse link
G Mc1r melanocortin 1 receptor ISO RGD PMID:20126537 RGD:5687319 NCBI chr19:56,215,420...56,219,987 JBrowse link
G Meox1 mesenchyme homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr10:89,797,011...89,817,009
Ensembl chr10:89,797,038...89,816,491 		JBrowse link
G Mir155 microRNA 155 treatment IEP RGD PMID:29404871 RGD:21079472 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667 		JBrowse link
G Mir21 microRNA 21 treatment IEP RGD PMID:29282578 RGD:41404666 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301 		JBrowse link
G Mki67 marker of proliferation Ki-67 ISO RGD PMID:21294775 RGD:6483538 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454 		JBrowse link
G Mmp3 matrix metallopeptidase 3 IEP
ISO		 mRNA:increased expression:skin, lymph node RGD PMID:16977379, PMID:10359808 RGD:2325935, RGD:8693317 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579 		JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP
ISO		 mRNA:increased expression:skin, lymph node RGD PMID:16977379, PMID:10359808, PMID:10415717 RGD:2325935, RGD:8693317, RGD:8547869 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520 		JBrowse link
G Mrc1 mannose receptor, C type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr17:81,352,700...81,433,743
Ensembl chr17:81,352,700...81,433,743 		JBrowse link
G Mxd1 max dimerization protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr 4:118,451,752...118,472,150
Ensembl chr 4:118,449,882...118,472,179 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472 		JBrowse link
G Nat1 N-acetyltransferase 1 susceptibility ISO DNA:polymorphism: : RGD PMID:19663877 RGD:8552666 NCBI chr16:23,970,742...23,991,573
Ensembl chr16:23,970,743...23,991,573 		JBrowse link
G Nat2 N-acetyltransferase 2 susceptibility ISO DNA:polymorphisms: : RGD PMID:16533241 RGD:8552663 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23564646 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Ninj1 ninjurin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr17:15,866,235...15,881,284
Ensembl chr17:15,866,237...15,881,327 		JBrowse link
G Numa1 nuclear mitotic apparatus protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr 1:167,044,544...167,091,453
Ensembl chr 1:167,051,209...167,091,453 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase ISO RGD PMID:15677345 RGD:8657146 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326 		JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr 7:54,247,460...54,249,664
Ensembl chr 7:54,247,460...54,249,664 		JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr20:8,165,423...8,169,557
Ensembl chr20:8,165,307...8,169,555 		JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889 		JBrowse link
G Prdx4 peroxiredoxin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr  X:43,495,453...43,512,994
Ensembl chr  X:43,497,763...43,512,991 		JBrowse link
G Qpct glutaminyl-peptide cyclotransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr 6:1,657,110...1,689,575
Ensembl chr 6:1,657,331...1,689,559 		JBrowse link
G Rab32 RAB32, member RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr 1:4,638,663...4,653,220
Ensembl chr 1:4,637,491...4,653,210 		JBrowse link
G Rgs1 regulator of G-protein signaling 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr13:61,066,196...61,070,772
Ensembl chr13:61,066,153...61,070,599 		JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765 		JBrowse link
G Sele selectin E ISO CTD Direct Evidence: marker/mechanism CTD PMID:17597826 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374397 NCBI chr19:54,693,959...54,722,563
Ensembl chr19:54,693,959...54,722,563 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461 		JBrowse link
G Socs2 suppressor of cytokine signaling 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr 7:36,495,496...36,500,878
Ensembl chr 7:36,495,480...36,499,784 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14555839 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901 		JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr11:80,927,601...80,981,424
Ensembl chr11:80,927,601...80,981,422 		JBrowse link
G Stac SH3 and cysteine rich domain ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr 8:119,820,664...119,941,867
Ensembl chr 8:119,821,901...119,889,661 		JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member susceptibility ISO RGD PMID:9303338 RGD:6482276 NCBI chr20:3,995,544...4,009,587
Ensembl chr20:3,995,544...4,009,587 		JBrowse link
G Tlr4 toll-like receptor 4 ISO RGD PMID:20711192, PMID:18725520 RGD:7777133, RGD:7794737 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052 		JBrowse link
G Tlr7 toll-like receptor 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr  X:28,486,836...28,513,004
Ensembl chr  X:28,486,869...28,512,957 		JBrowse link
G Tmsb10 thymosin, beta 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17597826 NCBI chr 4:100,882,216...100,883,303
Ensembl chr 4:100,882,216...100,883,275 		JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15849067 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tnfaip6 TNF alpha induced protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 PMID:17374397 NCBI chr 3:37,545,238...37,564,704
Ensembl chr 3:37,545,238...37,564,699 		JBrowse link
G Tslp thymic stromal lymphopoietin treatment ISO RGD PMID:30187507 RGD:38596345 NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361 		JBrowse link
G Upp1 uridine phosphorylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16033404 NCBI chr14:89,314,234...89,334,060
Ensembl chr14:89,314,176...89,334,276 		JBrowse link
G Vegfa vascular endothelial growth factor A IEP
ISO		 mRNA:protein:skin: RGD PMID:7876550, PMID:7876550 RGD:7421586, RGD:7421586 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
allergic cutaneous vasculitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf3 colony stimulating factor 3 treatment ISO associated with Severe Congenital Neutropenia; RGD PMID:20100783 RGD:11039037 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157 		JBrowse link
allergic rhinitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A severity ISO DNA:snp:exon:c.1236C>T (human) RGD PMID:24040855 RGD:8657076 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515 		JBrowse link
G Ace angiotensin I converting enzyme no_association ISO DNA:deletion:intron:IVS16+1464-1751del (human) RGD PMID:15112973 RGD:8142345 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822 		JBrowse link
G Bcl2 BCL2, apoptosis regulator IEP mRNA, protein:increased expression:nasal mucosa (rat) RGD PMID:15362690 RGD:11522724 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:29028686 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 treatment IDA RGD PMID:23089405 RGD:7248414 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575 		JBrowse link
G Ccl26 C-C motif chemokine ligand 26 ISO protein:increased expression:oronasal secretion (human) RGD PMID:23883806 RGD:7364793 NCBI chr12:24,157,182...24,161,870
Ensembl chr12:24,158,766...24,161,869 		JBrowse link
G Cd40 CD40 molecule ISO protein:increased expression:lymphocyte RGD PMID:19086656 RGD:8547782 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704 		JBrowse link
G Cd40lg CD40 ligand ISO protein:increased expression:lymphocyte RGD PMID:19086656 RGD:8547782 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 treatment ISO RGD PMID:10436391 RGD:11344920 NCBI chr 9:67,699,397...67,706,068
Ensembl chr 9:67,699,379...67,706,065 		JBrowse link
G F2 coagulation factor II ISO protein:increased expression:nasal mucus RGD PMID:21711961 RGD:5147783 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031 		JBrowse link
G Fcgr3a Fc fragment of IgG receptor IIIa susceptibility ISO DNA:polymorphism:exon:p.F158V(rs396991)(human) RGD PMID:18199088 RGD:5508449 NCBI chr13:89,385,775...89,396,047
Ensembl chr13:89,385,859...89,396,051 		JBrowse link
G Hrh1 histamine receptor H 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23333628 NCBI chr 4:146,374,596...146,458,148
Ensembl chr 4:146,455,332...146,457,074 		JBrowse link
G Ifng interferon gamma treatment ISO
IDA		 associated with Asthma RGD PMID:12787306, PMID:18510219 RGD:7829803, RGD:10755770 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Il10 interleukin 10 treatment ISO RGD PMID:23883806, PMID:23253209 RGD:7364793, RGD:7364818 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392 		JBrowse link
G Il13 interleukin 13 susceptibility
no_association		 ISO DNA:polymorphism:exon:c. 2044G>A (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds:p.R130Q (rs20541) (human)
DNA:SNPs:promoter, cds:-1112C>T, p.R130Q (rs1800925, rs20541) (human)
DNA:SNP:promoter:-1512A>C (rs1881457) (human)		 CTD
OMIM		 PMID:17091279, PMID:22852128, PMID:12928861, PMID:23996716 RGD:4152796, RGD:8549518, RGD:8549516, RGD:8549501 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466 		JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 ISO protein:increased expression:serum RGD PMID:21462799 RGD:8549521 NCBI chr  X:118,443,955...118,514,716
Ensembl chr  X:118,443,823...118,513,061 		JBrowse link
G Il17a interleukin 17A susceptibility ISO DNA:snp:promoter:c.-444A>G (human)
mRNA:increased expression:peripheral blood mononuclear cell (human)		 RGD PMID:22507625, PMID:21535180 RGD:9068429, RGD:5147409 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786 		JBrowse link
G Il18 interleukin 18 severity
no_association		 ISO DNA:SNP:promoter:-137G>C (rs187238) (human)
DNA:SNP:promoter:-140C>G (rs360721) (human)		 RGD PMID:22840759, PMID:22840759 RGD:8655914, RGD:8655914 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299 		JBrowse link
G Il1b interleukin 1 beta ISO protein:increased expression:nasal mucus RGD PMID:7750009 RGD:7401199 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il2 interleukin 2 IEP RGD PMID:12592663 RGD:8662963 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854 		JBrowse link
G Il4 interleukin 4 treatment ISO
IEP		 RGD PMID:9893928, PMID:24620662, PMID:8908280, PMID:14653048 RGD:7829796, RGD:11522769, RGD:7829827, RGD:7829802 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531 		JBrowse link
G Il5 interleukin 5 treatment IEP RGD PMID:23934070, PMID:24620662 RGD:11354976, RGD:11522769 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587 		JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming IEP mRNA, protein:increased expression:nasal cavity epithelium RGD PMID:22972875 RGD:7364746 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO mRNA:increased expression:nasal mucosa (human) RGD PMID:23858718 RGD:8547523 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492 		JBrowse link
G Pon1 paraoxonase 1 severity ISO protein:decreased activity:plasma (human) RGD PMID:23406590 RGD:8547583 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IEP protein:increased expression:nasal cavity epithelium RGD PMID:24012634 RGD:7775060 NCBI chr 1:248,982,039...250,300,952 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16979129 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 ISO RGD PMID:20487636 RGD:5144132 NCBI chr20:1,814,661...1,833,033
Ensembl chr20:1,814,661...1,818,800 		JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 ISO mRNA:decreased expression:nasal mucosa, lung RGD PMID:17882576 RGD:5144135 NCBI chr 1:225,279,698...225,283,246
Ensembl chr 1:225,279,676...225,283,326 		JBrowse link
G Scgb3a2 secretoglobin, family 3A, member 2 susceptibility ISO DNA:SNP: :rs7726552 (human) RGD PMID:21410962 RGD:5144225 NCBI chr18:38,292,822...38,295,744
Ensembl chr18:38,292,701...38,295,831 		JBrowse link
G Serpine1 serpin family E member 1 ISO mRNA:increased expression:nasal mucosa (mouse) RGD PMID:21339035 RGD:8547809 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482 		JBrowse link
G Tacr1 tachykinin receptor 1 IEP mRNA:increased expression:nasal mucosa RGD PMID:12768696 RGD:5147835 NCBI chr 4:113,247,236...113,416,139
Ensembl chr 4:113,247,795...113,414,504 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 treatment IEP RGD PMID:31368266 RGD:14995445 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Tlr2 toll-like receptor 2 severity ISO DNA:polymorphism:cds:p.R753Q(human)
protein:increased expression:neutrophil:
mRNA:decreased expression:nasal mucosa:		 RGD PMID:22402138, PMID:22555057, PMID:18381801, PMID:18219831 RGD:7800732, RGD:8552993, RGD:8552972, RGD:7800742 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061 		JBrowse link
G Tlr4 toll-like receptor 4 severity
treatment
susceptibility
no_association		 ISO DNA:polymorphism:cds:p.D299G(human)
protein:increased expression:nasal lavage,leukocyte, bone marrow:
protein:decreased expression:nasal mucosa:
DNA:SNP: :rs1927911(human)
DNA:polymorphism: :4216G>C(human)		 RGD PMID:22402138, PMID:22555057, PMID:22577387, PMID:17069098, PMID:23639307, PMID:19763595 RGD:7800732, RGD:8552993, RGD:7800740, RGD:7800738, RGD:7800736, RGD:4145354 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052 		JBrowse link
G Tlr9 toll-like receptor 9 ISO protein:decreased expression:nasal mucosa: RGD PMID:22577387 RGD:7800740 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171 		JBrowse link
Allergic Rhinoconjunctivitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 treatment ISO associated with Eosinophilic Esophagitis; DNA:polymorphisms:: RGD PMID:26416193 RGD:11352743 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007 		JBrowse link
G Il3 interleukin 3 susceptibility ISO DNA:SNP: :rs40401(human) RGD PMID:23953855 RGD:13506915 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973 		JBrowse link
Anaphylaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 disease_progression IMP RGD PMID:20959119 RGD:6893644 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985 		JBrowse link
G Agt angiotensinogen ISO RGD PMID:1422942 RGD:8548893 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Aspg asparaginase ISO CTD Direct Evidence: marker/mechanism CTD PMID:65671 NCBI chr 6:136,682,279...136,701,673
Ensembl chr 6:136,682,126...136,701,628 		JBrowse link
G Btk Bruton tyrosine kinase treatment IMP RGD PMID:22228807 RGD:11040701 NCBI chr  X:105,360,922...105,390,580
Ensembl chr  X:105,360,922...105,390,580 		JBrowse link
G Cabs1 calcium binding protein, spermatid associated 1 treatment ISO RGD PMID:25632019 RGD:14400306 NCBI chr14:21,746,294...21,748,356
Ensembl chr14:21,746,295...21,748,356 		JBrowse link
G Cma1 chymase 1 ISO protein:increased expression:lung, mast cell (human) RGD PMID:17081716 RGD:5128820 NCBI chr15:34,601,037...34,603,819
Ensembl chr15:34,601,037...34,603,819 		JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa susceptibility ISO associated with Agammaglobulinemia;DNA:mutation:splice junction: RGD PMID:23545275, PMID:26396093 RGD:11040993, RGD:11040995 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036 		JBrowse link
G Hdac3 histone deacetylase 3 ISO RGD PMID:24619412 RGD:9590165 NCBI chr18:31,073,057...31,094,347
Ensembl chr18:31,073,058...31,094,303 		JBrowse link
G Hp haptoglobin ISO RGD PMID:12147031 RGD:11041789 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804 		JBrowse link
G Il4 interleukin 4 ISO mRNA:increased expression:lung, intestine, spleen
associated with cystic echinococcosis; protein:increased expression:blood		 RGD PMID:24468678, PMID:28095662 RGD:10402796, RGD:14696684 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531 		JBrowse link
G Kng2 kininogen 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7623993 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Ltb4r leukotriene B4 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:10934231 NCBI chr15:34,449,299...34,453,352
Ensembl chr15:34,452,116...34,453,171 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19767079 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 IMP RGD PMID:18480553 RGD:2300247 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP
ISO		 RGD PMID:18480553, PMID:17822719 RGD:2300247, RGD:1642600 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 IMP RGD PMID:21604443 RGD:7207802 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619 		JBrowse link
G Wfdc6a WAP four-disulfide core domain 6A ISO CTD Direct Evidence: marker/mechanism CTD PMID:20693069 NCBI chr 3:161,036,703...161,040,511
Ensembl chr 3:161,036,703...161,040,511 		JBrowse link
angioedema term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:8458210 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863 		JBrowse link
G F12 coagulation factor XII ISO DNA:missense:exon:T309K,T309R
ClinVar Annotator: match by term: Quincke edema		 ClinVar PMID:16638441 PMID:25741868, PMID:16638441 RGD:1601106 NCBI chr17:9,736,577...9,744,420
Ensembl chr17:9,736,577...9,744,420 		JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: marker/mechanism CTD PMID:16184341 PMID:18453163 PMID:20547619 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889 		JBrowse link
G RT1-Bb RT1 class II, locus Bb ISO CTD Direct Evidence: marker/mechanism CTD PMID:15784113 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15784113 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190 		JBrowse link
G Serping1 serpin family G member 1 susceptibility ISO DNA:mutations:exon
ClinVar Annotator: match by term: Angioedema		 ClinVar PMID:12402344 RGD:1600545 NCBI chr 3:72,161,230...72,171,109
Ensembl chr 3:72,161,189...72,171,078 		JBrowse link
G Slc34a1 solute carrier family 34 member 1 ISO ClinVar Annotator: match by term: Quincke edema ClinVar PMID:16638441 PMID:25741868 NCBI chr17:9,747,766...9,762,739
Ensembl chr17:9,747,752...9,762,813 		JBrowse link
G Sytl2 synaptotagmin-like 2 ISO ClinVar Annotator: match by term: Angioedema ClinVar PMID:28327206 NCBI chr 1:154,536,592...154,599,515
NCBI chr 1:156,334,298...156,440,327
Ensembl chr 1:154,579,949...154,599,430
Ensembl chr 1:154,579,949...154,599,430 		JBrowse link
G Xpnpep2 X-prolyl aminopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16175507 NCBI chr  X:134,940,656...134,969,874
Ensembl chr  X:134,940,615...134,969,996 		JBrowse link
Angioedema Induced by ACE Inhibitors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase ISO ClinVar Annotator: match by term: Angioedema induced by ACE inhibitors, susceptibility to ClinVar PMID:1551674 PMID:1972698 PMID:1978554 PMID:1978555 PMID:2503817 PMID:2912069 PMID:3393536 PMID:4974311 PMID:5305539 PMID:5369703 PMID:6698555 PMID:7203486 PMID:8611726 PMID:8860013 PMID:9342374 PMID:11445808 PMID:12768444 PMID:14278484 PMID:15315792 PMID:15502081 PMID:16119988 PMID:19594365 PMID:22018328 PMID:22906047 PMID:23479361 PMID:24460025 PMID:24586352 PMID:25326637 PMID:25741868 PMID:28492532 PMID:32860008 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926 		JBrowse link
G Xpnpep2 X-prolyl aminopeptidase 2 susceptibility ISO ClinVar Annotator: match by term: Angioedema induced by ACE inhibitors, susceptibility to
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:16175507 PMID:20625347 PMID:21898657 NCBI chr  X:134,940,656...134,969,874
Ensembl chr  X:134,940,615...134,969,996 		JBrowse link
arthus reaction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase treatment IMP RGD PMID:22228807 RGD:11040701 NCBI chr  X:105,360,922...105,390,580
Ensembl chr  X:105,360,922...105,390,580 		JBrowse link
G Cfd complement factor D IDA RGD PMID:10605043 RGD:1624328 NCBI chr 7:12,634,216...12,635,939
Ensembl chr 7:12,634,216...12,635,943 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO RGD PMID:23470165 RGD:9068463 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514 		JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa treatment ISO RGD PMID:10762218 RGD:9588604 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036 		JBrowse link
aspergillosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor ISO DNA:SNP:promoter:-374T>A (human) RGD PMID:22114731 RGD:8695981 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 ISO associated with Neutropenia;mRNA:increased expression:lung RGD PMID:19783686 RGD:5130908 NCBI chr 5:58,181,025...58,182,969
Ensembl chr 5:58,181,026...58,183,017 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 ISO associated with Neutropenia RGD PMID:19783686 RGD:5130908 NCBI chr10:87,057,335...87,067,444
Ensembl chr10:87,057,136...87,067,456 		JBrowse link
G Cd209 CD209 molecule ISO RGD PMID:21381282 RGD:5131183 NCBI chr12:2,406,879...2,413,324
Ensembl chr12:2,406,879...2,413,324 		JBrowse link
G Cftr CF transmembrane conductance regulator severity ISO RGD PMID:22135344 RGD:35673332 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676 		JBrowse link
G Clec1a C-type lectin domain family 1, member A susceptibility ISO ClinVar Annotator: match by term: Aspergillosis, susceptibility to
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:29489751 NCBI chr 4:163,191,503...163,214,678
Ensembl chr 4:163,191,503...163,214,678 		JBrowse link
G Clec7a C-type lectin domain containing 7A susceptibility ISO ClinVar Annotator: match by term: Aspergillosis, susceptibility to
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:19864674 PMID:20807886 PMID:24033266 NCBI chr 4:163,216,152...163,227,367
Ensembl chr 4:163,216,163...163,227,334 		JBrowse link
G Crp C-reactive protein treatment ISO RGD PMID:20879853 RGD:9495929 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713 		JBrowse link
G Il15 interleukin 15 ISO DNA:polymorphism (human) RGD PMID:16893395 RGD:4981337 NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594 		JBrowse link
G Mbl1 mannose binding lectin 1 susceptibility ISO RGD PMID:20064561 RGD:8694071 NCBI chr16:18,736,154...18,742,193
Ensembl chr16:18,736,154...18,742,193 		JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO RGD PMID:20064561 RGD:8694071 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962 		JBrowse link
G S100b S100 calcium binding protein B ISO DNA:SNP: :427C>T (human) RGD PMID:22114731 RGD:8695981 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856 		JBrowse link
G Tlr1 toll-like receptor 1 susceptibility ISO DNA:SNPs: :p.R80T, p.N248S (human) RGD PMID:16461792 RGD:4889535 NCBI chr14:45,062,662...45,065,014
Ensembl chr14:45,062,662...45,081,991 		JBrowse link
G Tlr2 toll-like receptor 2 ISO mRNA:increased expression:lung RGD PMID:19781388 RGD:4145322 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061 		JBrowse link
G Tlr6 toll-like receptor 6 susceptibility ISO DNA:SNP: :p.S249P (human) RGD PMID:16461792 RGD:4889535 NCBI chr14:45,024,351...45,041,188
Ensembl chr14:45,024,351...45,046,446 		JBrowse link
aspirin-induced respiratory disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacng6 calcium voltage-gated channel auxiliary subunit gamma 6 susceptibility ISO DNA:SNP,haplotype:rs192808(human) RGD PMID:20860846 RGD:13524562 NCBI chr 1:64,307,684...64,322,124
Ensembl chr 1:64,305,438...64,321,241 		JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159, PMID:20022477 RGD:4145619 NCBI chr 8:133,026,539...133,040,999
Ensembl chr 8:133,029,625...133,040,997 		JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 PMID:17641958 PMID:20485159 NCBI chr  X:77,671,028...77,700,491
Ensembl chr  X:77,674,150...77,700,269 		JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 ISO DNA:SNPs: :-819T>G, 2078C>T, 2534A>G (human)
CTD Direct Evidence: marker/mechanism		 CTD PMID:16502481 PMID:20485159, PMID:15970796 RGD:5144000 NCBI chr15:54,903,290...54,941,742
Ensembl chr15:54,905,274...54,906,203 		JBrowse link
G Fancc FA complementation group C ISO DNA:haplotype::rs4647416(human) RGD PMID:21670957 RGD:11045795 NCBI chr17:826,512...955,703
Ensembl chr17:833,509...955,615 		JBrowse link
G Il4 interleukin 4 susceptibility ISO DNA:SNPs:promoter,5'UTR,intron:multiple RGD PMID:20921925 RGD:11528633 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531 		JBrowse link
G Ltc4s leukotriene C4 synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:9393345 PMID:9466979 PMID:10970818 PMID:20485159 NCBI chr10:35,736,486...35,743,088
Ensembl chr10:35,737,664...35,739,625 		JBrowse link
G Ms4a2 membrane spanning 4-domains A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chr 1:227,957,363...227,965,312
Ensembl chr 1:227,957,302...227,965,386 		JBrowse link
G Postn periostin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18391768 NCBI chr 2:143,656,820...143,688,087
Ensembl chr 2:143,656,793...143,688,087 		JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr 1:226,976,455...226,995,641
Ensembl chr 1:226,993,250...226,994,849 		JBrowse link
G Ptger2 prostaglandin E receptor 2 ISO ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD		 PMID:15496426 PMID:16502481 NCBI chr15:19,336,029...19,349,759
Ensembl chr15:19,338,175...19,350,210 		JBrowse link
G Ptgir prostaglandin I2 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr 1:78,833,449...78,835,832
Ensembl chr 1:78,833,157...78,837,623 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO protein:increased expression:mast cell
CTD Direct Evidence: marker/mechanism		 CTD PMID:16502481 PMID:20485159, PMID:9487340 RGD:5143936 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G RT1-Ba RT1 class II, locus Ba susceptibility ISO RGD PMID:25975240 RGD:11074090 NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721 		JBrowse link
G RT1-Bb RT1 class II, locus Bb susceptibility ISO RGD PMID:25975240 RGD:11074090 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 susceptibility ISO RGD PMID:25975240 RGD:11074090 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190 		JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member ISO RGD PMID:21796142 RGD:5147839 NCBI chr20:3,995,544...4,009,587
Ensembl chr20:3,995,544...4,009,587 		JBrowse link
G Tbx21 T-box transcription factor 21 ISO ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD		 PMID:15806396 PMID:16502481 NCBI chr10:85,032,799...85,049,331
Ensembl chr10:85,032,799...85,049,331 		JBrowse link
G Tbxa2r thromboxane A2 receptor susceptibility ISO DNA:polymorphism: :795T>C (human)
CTD Direct Evidence: marker/mechanism		 CTD PMID:16502481 PMID:20485159, PMID:15898979 RGD:11059537 NCBI chr 7:11,253,153...11,259,233
Ensembl chr 7:11,253,180...11,257,977 		JBrowse link
asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A ISO protein:increased expression:blood, lymphocyte RGD PMID:19484671 RGD:4890020 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 ISO RGD PMID:18931056 RGD:5128825 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196 		JBrowse link
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase no_association ISO RGD PMID:19771478, PMID:16008680 RGD:5128835, RGD:5128831 NCBI chr 3:4,374,679...4,394,374
Ensembl chr 3:4,374,602...4,394,428 		JBrowse link
G Ace angiotensin I converting enzyme susceptibility ISO DNA:polymorphism (human) RGD PMID:19484664, PMID:19383228 RGD:4140913, RGD:4140919 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822 		JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 ISO DNA:hypermethylation:promoter RGD PMID:19221603 RGD:13831295 NCBI chr 9:84,569,601...84,593,565
Ensembl chr 9:84,569,597...84,593,565 		JBrowse link
G Ada adenosine deaminase susceptibility ISO DNA:polymorphisms (human) RGD PMID:16754522 RGD:5128848 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947 		JBrowse link
G Adam33 ADAM metallopeptidase domain 33 susceptibility
no_association
disease_progression		 ISO mRNA:increased expression:lung
DNA:polymorphism: :p.M764T (human)
DNA:SNPs:introns,exon:7575G>A, 11188A>T, 12433T>C (human)
mRNA:increased expression:bronchus
DNA:SNPs (human)
DNA:SNPs: :multiple (human)		 RGD
GAD		 PMID:19635592, PMID:17961406, PMID:16893396, PMID:15118671, PMID:17339047, PMID:19940503, PMID:18778489 RGD:4145360, RGD:4145379, RGD:4145382, RGD:1331525, RGD:4145380, RGD:4145359, RGD:4145378 NCBI chr 3:123,595,018...123,607,549
Ensembl chr 3:123,595,560...123,607,352 		JBrowse link
G Adam8 ADAM metallopeptidase domain 8 severity ISO mRNA:increased expression:bronchus
mRNA:increased expression:respiratory tract		 RGD PMID:17339047, PMID:20194813, PMID:19373511 RGD:4145380, RGD:5128872, RGD:5128878 NCBI chr 1:212,317,510...212,332,895
Ensembl chr 1:212,317,848...212,330,349 		JBrowse link
G Adcy2 adenylate cyclase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 1:37,043,071...37,698,390
Ensembl chr 1:37,507,276...37,698,390 		JBrowse link
G Adcyap1r1 ADCYAP receptor type I ISO CTD Direct Evidence: marker/mechanism CTD PMID:21059121 NCBI chr 4:85,662,809...85,711,696
Ensembl chr 4:85,662,892...85,711,696 		JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide susceptibility ISO protein:increased expression:respiratory system fluid/secretion
DNA:SNPs: :rs1154404, rs28730619 (human)		 RGD PMID:19395503, PMID:17543375, PMID:19514054, PMID:15919956 RGD:5128891, RGD:5128882, RGD:5128890, RGD:5128892 NCBI chr 2:243,728,500...243,740,907
Ensembl chr 2:243,700,784...243,740,899 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO RGD PMID:19168697 RGD:5686821 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488 		JBrowse link
G Adora1 adenosine A1 receptor ISO DNA:SNPs: :1405C>T (human)
protein:increased expression:bronchus		 RGD PMID:19019667, PMID:20400685, PMID:17959644 RGD:4890386, RGD:4145444, RGD:5129097 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852 		JBrowse link
G Adora2a adenosine A2a receptor ISO mRNA:decreased expression:aorta
DNA:SNP (human)		 RGD PMID:17293374, PMID:18310516, PMID:19019667, PMID:16339780 RGD:4890380, RGD:4890366, RGD:4890386, RGD:4890385 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873 		JBrowse link
G Adrb2 adrenoceptor beta 2 susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Beta-2-adrenoreceptor agonist, reduced response to
DNA:SNP: :-1023A>G (human)
DNA:SNPs: :p.R16G, p.Q27E (human)
DNA:SNPs:promoter:multiple (human)
DNA:polymorphism: :p.R16G (human)
DNA:SNP: :p.Q27E (human)		 CTD
OMIM
ClinVar		 PMID:8383511 PMID:15284533 PMID:16596417, PMID:1655856, PMID:15118671, PMID:19638684, PMID:18785519, PMID:19423772, PMID:20443840, PMID:19029431, PMID:20004781, PMID:19800676, PMID:18569231 RGD:5129113, RGD:1331525, RGD:4145081, RGD:4145094, RGD:4145107, RGD:4145108, RGD:4145092, RGD:4145105, RGD:4145061, RGD:4145096 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834 		JBrowse link
G Ager advanced glycosylation end product-specific receptor treatment
onset		 ISO
IDA
IEP		 protein:decreased expression:lung (rat) RGD PMID:21920897, PMID:23304218, PMID:23304218 RGD:6767554, RGD:7244279, RGD:7244279 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a ISO
IMP		 RGD PMID:17877756, PMID:19080339 RGD:5147452, RGD:5147457 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 IEP mRNA, protein:increased expression:lung RGD PMID:19080339 RGD:5147457 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:9600491 PMID:11506308, PMID:15118671 RGD:1331525 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO protein:increased expression:lung RGD PMID:19628725, PMID:18692885 RGD:5509605, RGD:5509784 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase no_association
susceptibility
treatment
severity		 ISO DNA:polymorphism:promoter (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:blood, leukocyte
protein:increased expression:lung
DNA:repeat:promoter (human)
DNA:polymorphism:cds:p.E254K (human)		 CTD
OMIM		 PMID:20128419, PMID:9642160, PMID:12911785, PMID:8879219, PMID:11035107, PMID:19033731, PMID:10369259, PMID:16364163, PMID:17394438, PMID:18204779 RGD:4890407, RGD:5147467, RGD:5147465, RGD:5147462, RGD:4890422, RGD:4890408, RGD:734557, RGD:4890415, RGD:4890413, RGD:4890410 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein susceptibility
no_association		 ISO DNA:SNP: :rs10507391 (human)
mRNA:increased expression:blood, leukocyte
DNA:repeat:promoter:-169(A)21 (human)
DNA:substitution, repeat:promoter:-336G>A, -169(A)19-23 (human)
DNA:polymorphisms:intron:IVS2+12C>A, IVS2+105T>C (human)
protein:increased expression:lung
DNA:polymorphism:promoter (human)
DNA:SNPs (human)		 RGD PMID:20067482, PMID:9642160, PMID:10527888, PMID:12911785, PMID:15784112, PMID:8879219, PMID:11035107, PMID:20128419, PMID:18547289 RGD:4890405, RGD:5147467, RGD:5147466, RGD:5147465, RGD:5147464, RGD:5147462, RGD:4890422, RGD:4890407, RGD:4890409 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154 		JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor ISO protein:increased expression:serum RGD PMID:14621078 RGD:6904149 NCBI chr 5:78,975,690...78,986,021
Ensembl chr 5:78,975,678...78,985,990 		JBrowse link
G Ang angiogenin severity ISO protein:increased expression:sputum RGD PMID:16478840 RGD:6892719 NCBI chr15:28,022,926...28,028,636 JBrowse link
G Anxa1 annexin A1 ISO RGD PMID:22092555 RGD:7421657 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012 		JBrowse link
G Areg amphiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15696081 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179 		JBrowse link
G Arg1 arginase 1 ISO DNA:SNP: :rs2781667 (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (mouse)
mRNA, protein:increased expression:lung, mononuclear cell (human)		 CTD PMID:19281908 PMID:19800904, PMID:20124949, PMID:12813022, PMID:12813022 RGD:5129205, RGD:4143187, RGD:4143187 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863 		JBrowse link
G Arg2 arginase 2 severity
susceptibility		 ISO DNA:SNP: :rs3742879, rs17249437 (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (mouse)
DNA:SNPs (human)		 CTD PMID:19281908, PMID:20124949, PMID:12813022, PMID:16387594 RGD:5129205, RGD:4143187, RGD:5129207 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520 		JBrowse link
G Bcl2 BCL2, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:18357729 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bdkrb2 bradykinin receptor B2 onset ISO
IMP		 DNA:polymorphism:exon (human)
protein:increased expression:blood, eosinophil		 RGD PMID:11517947, PMID:14727005, PMID:8856156, PMID:19038786 RGD:4890456, RGD:4890454, RGD:4891042, RGD:4891028 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676 		JBrowse link
G Bdnf brain-derived neurotrophic factor susceptibility
severity		 ISO protein:decreased expression:blood, eosinophil
DNA:SNP,haplotypes: :rs10767664,rs12273539,rs962369(human)
DNA:polymorphisms: :p.V66M, -270C>T (human)
DNA:polymorphisms: :p.V66M (rs6265) (human)
protein:increased expression:plasma		 RGD PMID:12752594, PMID:21723144, PMID:17584309, PMID:19895626, PMID:20874832, PMID:11737043 RGD:4891122, RGD:8655967, RGD:4891067, RGD:4891117, RGD:4891063, RGD:4891123 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:8429434 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747 		JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B ISO protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chr 2:247,392,195...247,662,026
Ensembl chr 2:247,403,920...247,446,882 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 ISO protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494 		JBrowse link
G C3 complement C3 severity ISO DNA:SNPs: :multiple (human)
protein:increased expression:serum
DNA:SNP: :4896C>T (human)
DNA:SNP:intron:rs11569562 (human)
Interaction with IL4RA
protein:increased expression:respiratory system fluid/secretion		 RGD PMID:16355111, PMID:20589464, PMID:15278436, PMID:18566738, PMID:20402389, PMID:20395963, PMID:20802484, PMID:11591733 RGD:5129505, RGD:5129519, RGD:5129512, RGD:5129501, RGD:5129537, RGD:5129538, RGD:5129681, RGD:5129517 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167 		JBrowse link
G C3ar1 complement C3a receptor 1 severity ISO
IEP		 mRNA:increased expression:lung
protein:increased expression:lung, leukocyte		 RGD PMID:20045013, PMID:17544263, PMID:20802484, PMID:15940127, PMID:15278436 RGD:5129686, RGD:5129560, RGD:5129681, RGD:5129561, RGD:5129512 NCBI chr 4:155,681,767...155,691,240
Ensembl chr 4:155,684,029...155,690,869 		JBrowse link
G C5 complement C5 severity ISO
IDA		 mRNA:decreased expression:lung RGD PMID:10973279, PMID:20143644, PMID:20802484, PMID:15278436, PMID:11591795 RGD:5130158, RGD:5129706, RGD:5129681, RGD:5129512, RGD:1600651 NCBI chr 3:14,049,993...14,113,931
NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080 		JBrowse link
G C5ar1 complement C5a receptor 1 severity ISO
IEP		 protein:increased expression:lung, leukocyte
protein:increased expression:respiratory tract		 RGD PMID:20802484, PMID:17544263, PMID:15940127, PMID:16511606 RGD:5129681, RGD:5129560, RGD:5129561, RGD:5130166 NCBI chr 1:78,186,777...78,195,132
Ensembl chr 1:78,186,776...78,195,328 		JBrowse link
G Card11 caspase recruitment domain family, member 11 susceptibility ISO RGD PMID:16751370 RGD:11100037 NCBI chr12:15,700,600...15,844,512
Ensembl chr12:15,700,825...15,844,512 		JBrowse link
G Carm1 coactivator-associated arginine methyltransferase 1 IEP mRNA:decreased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr 8:22,577,723...22,622,555
Ensembl chr 8:22,577,715...22,622,560 		JBrowse link
G Casp1 caspase 1 ISO protein:increased expression:serum RGD PMID:12396474 RGD:5130192 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631 		JBrowse link
G Cat catalase severity ISO DNA:polymorphism:promoter:-21A>T (human)
CTD Direct Evidence: marker/mechanism
protein:decreased activity:respiratory system fluid/secretion
DNA:polymorphism:promoter:-262C>T (human)
protein:increased expression:erythrocyte		 CTD PMID:18048809, PMID:19373626, PMID:16622028, PMID:18048809, PMID:19475625 RGD:5130753, RGD:5130867, RGD:5130856, RGD:5130751 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Ccl1 C-C motif chemokine ligand 1 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:20455898 RGD:4891420 NCBI chr10:69,534,976...69,537,836
Ensembl chr10:69,534,933...69,537,882 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 susceptibility
treatment
severity		 ISO
IDA
IEP		 protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
DNA:polymorphism: :p.A23T (human)
mRNA:increased expression:lung		 CTD
OMIM		 PMID:16304252, PMID:22932891, PMID:17074272, PMID:9034156, PMID:17845580, PMID:18250471, PMID:20704746, PMID:17060636 RGD:5130930, RGD:7248416, RGD:4145461, RGD:4145451, RGD:4145457, RGD:4145392, RGD:4145387, RGD:4891485 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575 		JBrowse link
G Ccl17 C-C motif chemokine ligand 17 IEP
ISO		 mRNA:increased expression:lung
protein:increased expression:respiratory system fluid/secretion		 RGD PMID:15993846, PMID:15947487, PMID:20074456, PMID:20237293, PMID:11160256 RGD:2306304, RGD:4145513, RGD:4145487, RGD:4145486, RGD:4145603 NCBI chr19:10,619,220...10,620,671
Ensembl chr19:10,619,220...10,620,671 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 ISO protein:increased expression:bronchus submucosa, mast cell RGD PMID:16959919 RGD:5130911 NCBI chr 5:58,181,025...58,182,969
Ensembl chr 5:58,181,026...58,183,017 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 severity
treatment		 ISO
IEP		 protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (mouse)
DNA:haplotype::-2518A>G (human)
protein:increased expression:lung		 CTD PMID:19373627, PMID:19373627, PMID:12055264, PMID:25441643, PMID:23454776, PMID:17964702, PMID:20205697 RGD:4891466, RGD:11528570, RGD:11528569, RGD:8551842, RGD:2307055, RGD:4145509 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 ISO protein:increased expression:respiratory system fluid/secretion
associated with Allergic Rhinitis;protein:increased expression:serum		 RGD PMID:18422729, PMID:22469443 RGD:7483597, RGD:7483618 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001 		JBrowse link
G Ccl22 C-C motif chemokine ligand 22 ISO
IEP		 protein:increased expression:respiratory system fluid/secretion
mRNA, protein:increased expression:respiratory system mucosa, respiratory system fluid/secretion
mRNA:increased expression:lung		 RGD PMID:18316417, PMID:10384142, PMID:18684970, PMID:15993846 RGD:4891474, RGD:4891475, RGD:4145489, RGD:2306304 NCBI chr19:10,674,189...10,681,145
Ensembl chr19:10,674,189...10,681,145 		JBrowse link
G Ccl24 C-C motif chemokine ligand 24 susceptibility ISO DNA:SNPs: :179T>C, 275C>T (human)
protein:increased expression:respiratory system fluid/secretion
DNA:SNP: :1265A>G (human)
DNA:SNPs: :304C>A, 1272A>G (human)
protein:increased expression:plasma		 RGD PMID:15207712, PMID:17548626, PMID:12952266, PMID:12761043, PMID:18712274, PMID:17060636, PMID:16304252 RGD:4891495, RGD:4891484, RGD:4891496, RGD:5130932, RGD:4891483, RGD:4891485, RGD:5130930 NCBI chr12:24,131,529...24,152,626
Ensembl chr12:24,148,567...24,152,625 		JBrowse link
G Ccl26 C-C motif chemokine ligand 26 treatment ISO
IDA		 protein:increased expression:plasma
DNA:SNPs: :77C>T, 2497T>G (human)
DNA:SNPs: :77C>T, 716A>G, 1579G>A (human)		 RGD PMID:16304252, PMID:25399816, PMID:25530546, PMID:15207712, PMID:18712274 RGD:5130930, RGD:11087575, RGD:11081163, RGD:4891495, RGD:4891483 NCBI chr12:24,157,182...24,161,870
Ensembl chr12:24,158,766...24,161,869 		JBrowse link
G Ccl27 C-C motif chemokine ligand 27 ISO RGD PMID:19541356 RGD:5130899 NCBI chr 5:58,159,066...58,166,182
Ensembl chr 5:58,159,066...58,163,584 		JBrowse link
G Ccl28 C-C motif chemokine ligand 28 ISO mRNA:increased expression:lung (mouse) RGD PMID:16290206 RGD:4892195 NCBI chr 2:52,379,341...52,403,979
Ensembl chr 2:52,379,341...52,404,246 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 ISO RGD PMID:18774390 RGD:5130915 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 susceptibility IEP
ISO		 protein:increased expression:smooth muscle cell
CTD Direct Evidence: marker/mechanism
DNA:transition:5' utr:-403G>A (human)
protein:increased expression:lung, secretion (mouse)		 CTD PMID:8534483, PMID:18208670, PMID:20430255, PMID:20092989 RGD:2307112, RGD:4891381, RGD:4891430 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 ISO RGD PMID:21388664, PMID:19965981 RGD:5130983, RGD:5130979 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 severity ISO mRNA:increased expression:lung
associated with Respiratory Syncytial Virus Infections		 RGD PMID:15654816, PMID:15593301 RGD:5688158, RGD:5688159 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 susceptibility ISO DNA:SNP:cds:p.V64I (human)
DNA:haplotype:cds:p.V64I(human)
protein:increased expression:lung, dendritic cell (mouse)		 RGD PMID:17298432, PMID:23454776, PMID:19917684 RGD:4145110, RGD:8551842, RGD:8549811
G Ccr3 C-C motif chemokine receptor 3 ISO
IMP		 protein:increased expression:respiratory system fluid/secretion, neutrophil
DNA:SNP:exon:51T>C (human)		 RGD PMID:18699933, PMID:19017998, PMID:20220260, PMID:16978084, PMID:19657453, PMID:20134116, PMID:17145927 RGD:4145633, RGD:4145632, RGD:4145638, RGD:4145646, RGD:4145623, RGD:4145618, RGD:1601020 NCBI chr 8:133,026,539...133,040,999
Ensembl chr 8:133,029,625...133,040,997 		JBrowse link
G Ccr4 C-C motif chemokine receptor 4 IEP mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chr 8:122,530,152...122,535,959
Ensembl chr 8:122,530,624...122,532,070 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 no_association ISO DNA:frameshift mutation:cds:p.S185_T195del rs333 (human)
DNA:polymorphism, frameshift mutation: :-59029G>A, p.S185_T195del (rs333) (human)
mRNA:increased expression:lung (mouse)
protein:decreased expression:blood, lymphocyte (human)		 RGD PMID:20220260, PMID:23454776, PMID:16474097, PMID:18094012, PMID:15256090 RGD:4145638, RGD:8551842, RGD:4892093, RGD:4892088, RGD:4892108 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614 		JBrowse link
G Ccr6 C-C motif chemokine receptor 6 ISO protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chr 1:53,063,380...53,087,519
Ensembl chr 1:53,065,025...53,087,474 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 ISO protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chr10:87,057,335...87,067,444
Ensembl chr10:87,057,136...87,067,456 		JBrowse link
G Ccr8 C-C motif chemokine receptor 8 IEP mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chr 8:128,779,552...128,782,531
Ensembl chr 8:128,781,395...128,782,456 		JBrowse link
G Ccr9 C-C motif chemokine receptor 9 ISO mRNA, protein:increased expression:blood, mature NK T cell RGD PMID:16210593 RGD:5130925 NCBI chr 8:132,827,325...132,842,130
Ensembl chr 8:132,828,091...132,842,130 		JBrowse link
G Cd14 CD14 molecule severity
no_association
susceptibility		 ISO DNA:polymorphism:promoter:c. -260C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter:c. -159C>T (human)
DNA:SNPs: :
protein:increased expression:serum|DNA:polymorphism:promoter:c. -159C>T (human)		 CTD PMID:17607003, PMID:15940135, PMID:15741437, PMID:19096003, PMID:16387800, PMID:18312481 RGD:4144814, RGD:4144815, RGD:4144228, RGD:4144813, RGD:4144208 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153 		JBrowse link
G Cd209 CD209 molecule ISO RGD PMID:21471959 RGD:5131188 NCBI chr12:2,406,879...2,413,324
Ensembl chr12:2,406,879...2,413,324 		JBrowse link
G Cd209c CD209c molecule ISO RGD PMID:21471959 RGD:5131188 NCBI chr12:2,837,991...2,846,709
Ensembl chr12:2,838,128...2,843,772 		JBrowse link
G Cd274 CD274 molecule treatment ISO associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chr 1:247,519,890...247,539,659
Ensembl chr 1:247,519,939...247,537,943 		JBrowse link
G Cd28 Cd28 molecule ISO RGD PMID:21356099 RGD:5131612 NCBI chr 9:67,546,408...67,573,858
Ensembl chr 9:67,546,408...67,571,871 		JBrowse link
G Cd40 CD40 molecule treatment ISO
IDA
IEP		 RGD PMID:19220210, PMID:20205594, PMID:20205594, PMID:20941750, PMID:19159017 RGD:5132272, RGD:8547792, RGD:8547792, RGD:4892277, RGD:4144188 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704 		JBrowse link
G Cd40lg CD40 ligand severity ISO RGD PMID:9502776 RGD:11352238 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562 		JBrowse link
G Cd80 Cd80 molecule ISO RGD PMID:21352203, PMID:21051864, PMID:21440530 RGD:5132620, RGD:5132621, RGD:5132619 NCBI chr11:64,815,201...64,855,293
Ensembl chr11:64,827,635...64,855,353 		JBrowse link
G Cd86 CD86 molecule treatment ISO
IEP		 protein:increased expression:lung, alveolar macrophage (mouse)
protein:increased expression:blood, B cell (human)
protein:increased expression:lung, dendritic cell (rat)
DNA:snp:exon:p.I179V rs2681417 (human)		 RGD PMID:20941750, PMID:25344652, PMID:9449507, PMID:20668438, PMID:9551945, PMID:17513529 RGD:4892277, RGD:11354965, RGD:4892555, RGD:4892199, RGD:4892202, RGD:4892280 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795 		JBrowse link
G Cdh1 cadherin 1 ISO RGD PMID:21540309 RGD:5132878 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395 		JBrowse link
G Cdhr3 cadherin-related family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr 6:52,344,635...52,402,144
Ensembl chr 6:52,345,240...52,401,853 		JBrowse link
G Cftr CF transmembrane conductance regulator susceptibility ISO DNA:deletion: :F508del(human) RGD PMID:20298391 RGD:4140387 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676 		JBrowse link
G Chat choline O-acetyltransferase IEP Protein:decreased expression:lung epithelium RGD PMID:17328924 RGD:5686690 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131 		JBrowse link
G Chi3l1 chitinase 3 like 1 susceptibility ISO human gene in mouse model
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by null
DNA:snp:5' utr:g.-131C>G rs4950928 (human)
protein:increased secretion:serum (human)		 CTD
OMIM
ClinVar		 PMID:18403759, PMID:19414556, PMID:19568425, PMID:18003958 RGD:4892663, RGD:4892630, RGD:4892632 NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802 		JBrowse link
G Chia chitinase, acidic no_association ISO DNA:snps:5' utr, cds:multiple (human)
DNA:snps:multiple (human)
mRNA:increased expression:lung, epithelial cell (human)
mRNA:increased expression:lung (mouse)		 RGD PMID:16179638, PMID:20226308, PMID:19548841, PMID:15192232, PMID:14734765 RGD:4996473, RGD:5024922, RGD:5024921, RGD:4985150, RGD:4990463 NCBI chr 2:208,750,348...208,797,388
Ensembl chr 2:208,749,996...208,797,402 		JBrowse link
G Chml CHM like Rab escort protein ISO RGD PMID:18343558 RGD:5133238 NCBI chr13:93,740,759...93,742,624 JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 ISO RGD PMID:16931638 RGD:5133416 NCBI chr 1:224,869,087...224,885,101
Ensembl chr 1:224,882,439...224,884,205 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 ISO DNA:SNP: :rs6962027 (human) RGD PMID:19308904 RGD:5509586 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 severity ISO RGD PMID:20394512, PMID:18348887 RGD:5133437, RGD:5133438 NCBI chr17:63,990,599...64,463,222
Ensembl chr17:63,990,599...63,994,169 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex ISO RGD PMID:18643924 RGD:5133701 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169 		JBrowse link
G Clca1 chloride channel accessory 1 susceptibility ISO DNA:SNPs (human) RGD PMID:11296262, PMID:17898169, PMID:15318163 RGD:4145661, RGD:4145653, RGD:4145656 NCBI chr 2:250,897,980...250,923,711
Ensembl chr 2:250,897,969...250,923,744 		JBrowse link
G Cma1 chymase 1 severity
susceptibility
no_association		 ISO protein:increased expression:lung epithelium, mast cell (human)
DNA:duplications:3' utr:g.*254-?dupTG, dupGA (human)
DNA:polymorphism:5' utr:g.-1903G>A rs1800875 (human)		 RGD PMID:20813890, PMID:15924217, PMID:15248847 RGD:5128804, RGD:1625396, RGD:1625397 NCBI chr15:34,601,037...34,603,819
Ensembl chr15:34,601,037...34,603,819 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO DNA:SNP: :RS242941 (human)
DNA:SNPs: :rs1876828, rs242939, rs242941 (human)		 RGD PMID:19663668, PMID:16113459 RGD:5147485, RGD:5147488 NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 ISO DNA:SNPs: :multiple (human) RGD PMID:18408560 RGD:5130938 NCBI chr 4:85,286,371...85,329,374
Ensembl chr 4:85,286,372...85,329,362 		JBrowse link
G Crp C-reactive protein ISO protein:increased expression:serum RGD PMID:21140796 RGD:5131288 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713 		JBrowse link
G Csf2 colony stimulating factor 2 severity ISO protein:increased expression:lung
protein:increased expression:sputum		 RGD PMID:20405019, PMID:9717963, PMID:19213775 RGD:5131473, RGD:10449521, RGD:5131476 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070 		JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta IMP RGD PMID:17145927 RGD:1601020 NCBI chr 7:119,554,383...119,568,248
Ensembl chr 7:119,554,354...119,568,776 		JBrowse link
G Csf3 colony stimulating factor 3 ISO protein:increased expression:lung RGD PMID:21396376, PMID:20405019 RGD:5133731, RGD:5131473 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 severity
treatment
no_association		 ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :multiple (human)
DNA:SNP: :rs3087243 (human)
DNA:polymorphism:promoter:-318C>T (human)
DNA:SNPs:promoter, exon:-1147C>T, -318C>T, 49A>G (human)
DNA:polymorphisms:promoter, exon:-318C>T 49A>G (human)		 CTD PMID:28807506, PMID:15871446, PMID:11726402, PMID:17237396, PMID:15316504, PMID:19895365, PMID:16677453, PMID:12114354, PMID:18699801, PMID:16926542, PMID:16708626, PMID:17469155, PMID:12956753 RGD:4891529, RGD:11344922, RGD:4891514, RGD:4891519, RGD:4891526, RGD:4891517, RGD:4891522, RGD:4891510, RGD:4891528, RGD:4891516, RGD:4891527, RGD:4891521 NCBI chr 9:67,699,397...67,706,068
Ensembl chr 9:67,699,379...67,706,065 		JBrowse link
G Ctnna3 catenin alpha 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19187332 NCBI chr20:25,063,124...26,640,428
Ensembl chr20:26,516,836...26,589,209 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 ISO protein:increased expression:plasma RGD PMID:14657873 RGD:4891906 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 no_association ISO DNA:SNPs: :p.V249I, rs2669849 (human)
DNA:polymorphisms: :p.V249I, p.T280M (human)		 RGD PMID:21037587, PMID:17082760, PMID:17505143 RGD:4891882, RGD:4891895, RGD:4891904 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 severity ISO RGD PMID:20371397 RGD:5134983 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO protein:decreased expression:plasma RGD PMID:17302903, PMID:16602032, PMID:11994485 RGD:5135439, RGD:5135457, RGD:5135452 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930 		JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21150878 NCBI chr17:9,109,731...9,117,754
Ensembl chr17:9,109,731...9,117,750 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ISO mRNA:increased expression:lung RGD PMID:20045013 RGD:5129686 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 severity ISO RGD PMID:20371397 RGD:5134983 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595 		JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 ISO mRNA:increased expression:bronchus epithelium RGD PMID:17234659, PMID:9620668 RGD:5135243, RGD:5135265 NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 ISO RGD PMID:15210824 RGD:5135447 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 susceptibility
severity		 ISO DNA:SNP:intron:IVS1+234G>A (human)
protein:decreased expression:respiratory system fluid/secretion, T cell		 RGD PMID:18094012, PMID:16043121, PMID:16548899, PMID:17641057 RGD:4892088, RGD:5143934, RGD:5143932, RGD:5135484 NCBI chr  X:71,614,346...71,616,997
Ensembl chr  X:71,614,346...71,616,997 		JBrowse link
G Cyba cytochrome b-245 alpha chain susceptibility ISO DNA:polymorphism: :-930A>G (human)
DNA:SNPs: :-930A>G, 242C>T, 640A>G (human)		 RGD PMID:19459419, PMID:18716406 RGD:4311041, RGD:4772770 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO mRNA, protein:increased expression, decreased activity:lung RGD PMID:12415424 RGD:4892074 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 ISO DNA:polymorphism: :1934G>A (human) RGD PMID:19575027 RGD:5143944 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO mRNA:decreased expression:leukocyte
CTD Direct Evidence: marker/mechanism		 CTD PMID:28807506, PMID:20514434, PMID:17081494 RGD:4892076, RGD:4892220 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542 		JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 no_association
severity		 ISO DNA:SNPs:promoter, exon:multiple (human)
DNA:SNPs:promoter:-634C>T, -475A>C, -336A>G (human)
DNA:SNP: :927T>C (human)
mRNA, protein:increased expression:respiratory system mucosa 		RGD PMID:16771777, PMID:16630147, PMID:16776674, PMID:8087328, PMID:16387808, PMID:11591188, PMID:17153879, PMID:17689528, PMID:16123393 RGD:4889116, RGD:4784257, RGD:4782072, RGD:4888514, RGD:4843543, RGD:4848936, RGD:4781742, RGD:4781449, RGD:4847129 NCBI chr  X:77,671,028...77,700,491
Ensembl chr  X:77,674,150...77,700,269 		JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 ISO DNA:polymorphism: :601A>G (human)
DNA:polymorphism: :-1220A>C (human)		 RGD PMID:15475736, PMID:15454733 RGD:5144002, RGD:5144003 NCBI chr15:54,903,290...54,941,742
Ensembl chr15:54,905,274...54,906,203 		JBrowse link
G Dcn decorin IEP RGD PMID:16387756 RGD:2311423 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323 		JBrowse link
G Defb1 defensin beta 1 susceptibility ISO DNA:SNP: :-1816 T>C (human)
DNA:SNPs:5' utr:g.-52G>A, g.-44C>G, g.-20G>A (human)		 RGD PMID:15696078, PMID:16435024 RGD:4892263, RGD:4892254 NCBI chr16:75,294,385...75,309,127
Ensembl chr16:75,294,376...75,309,176 		JBrowse link
G Dnah5 dynein, axonemal, heavy chain 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 2:80,947,730...81,143,997
NCBI chr 2:81,159,060...81,337,560
Ensembl chr 2:80,948,658...81,143,447 		JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO DNA,mRNA:hypermethylation,decreased expression:promoter,respiratory tract:
CTD Direct Evidence: marker/mechanism		 CTD PMID:23423710, PMID:23196709 RGD:9588646 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495 		JBrowse link
G Dpp10 dipeptidyl peptidase like 10 ISO
IEP		 DNA:SNPs (human)
DNA:SNP: :rs10208402 (human)
DNA:SNP:exon (human)
protein:increased expression:bronchus		 RGD
GAD		 PMID:21103062, PMID:15118671, PMID:19672052, PMID:14566338, PMID:17967935 RGD:4889866, RGD:1331525, RGD:4892275, RGD:4892276, RGD:4892278 NCBI chr13:39,430,590...41,173,706
Ensembl chr13:39,434,217...39,643,361 		JBrowse link
G Ebi3 Epstein-Barr virus induced 3 ISO RGD PMID:21255010 RGD:5128488 NCBI chr 9:11,110,874...11,114,843
Ensembl chr 9:11,110,874...11,114,843 		JBrowse link
G Edn1 endothelin 1 ISO Severe Persistent Allergic Asthma; protein:increased secretion:lung (human)
CTD Direct Evidence: marker/mechanism
DNA:transition:intron:g.4124T>C (human)		 CTD PMID:16981460, PMID:20588001, PMID:11668616 RGD:4144895, RGD:4144869 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324 		JBrowse link
G Ednra endothelin receptor type A ISO RGD PMID:17448648, PMID:18632188 RGD:4892322, RGD:4892288 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703 		JBrowse link
G Ednrb endothelin receptor type B IEP
ISO		 mRNA:increased expression:bronchus, smooth muscle cell
DNA:polymorphism (human)		 RGD PMID:15245576, PMID:17470272, PMID:18632188 RGD:4892324, RGD:4892321, RGD:4892288 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354 		JBrowse link
G Egfr epidermal growth factor receptor severity IEP
ISO		 protein:increased expression:lung epithelium (rat)
protein:increased expression:bronchial epithelium (human)
protein:increased expression:lung epithelium (mouse)		 RGD PMID:19954006, PMID:12580917, PMID:21224214, PMID:21072743 RGD:5131870, RGD:5131468, RGD:5131633, RGD:5131642 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796 		JBrowse link
G Egr1 early growth response 1 ISO mRNA:increased expression:bronchoalveolar lavage cell (human)
DNA:snp:5' utr:g.-4071A>G rs7729723 (human)		 RGD PMID:11254538, PMID:18774390, PMID:18507785 RGD:5131985, RGD:5130915, RGD:5131993 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429 		JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 no_association ISO RGD PMID:12774215, PMID:11281413 RGD:5129158, RGD:5129157 NCBI chr 5:73,503,406...73,552,798
Ensembl chr 5:73,503,407...73,552,798 		JBrowse link
G Ephx1 epoxide hydrolase 1 susceptibility ISO DNA:SNPs:exons:p.Y113H (rs1051740), p.H139R (rs2234922) (human) RGD PMID:17711870 RGD:4889407 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579 		JBrowse link
G Epx eosinophil peroxidase severity
disease_progression		 ISO protein:increased activity:sputum,nasal,pharyngeal mucosa RGD PMID:26645423, PMID:12199967, PMID:20813885 RGD:11574908, RGD:13506892, RGD:13506891 NCBI chr10:75,160,690...75,171,774
Ensembl chr10:75,160,690...75,171,774 		JBrowse link
G Esr2 estrogen receptor 2 IEP mRNA:decreased expression:lung (rat) RGD PMID:18375789 RGD:8694127 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251 		JBrowse link
G F2 coagulation factor II ISO protein:increased expression:plasma
associated with Rhinosinusitis, associated with Nasal Polyps;protein:increased expression:nasal mucus		 RGD PMID:21658190, PMID:21711961 RGD:5147753, RGD:5147783 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 ISO RGD PMID:19864598 RGD:4892589 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275 		JBrowse link
G F7 coagulation factor VII treatment IDA RGD PMID:24523826 RGD:11040539 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945 		JBrowse link
G Fas Fas cell surface death receptor IEP mRNA:increased expression:eosinophil RGD PMID:16337971 RGD:1600350 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790 		JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia severity ISO Asthma symptoms persistent despite steroids in humans
Fatal asthma subjects		 RGD PMID:20937062, PMID:21388666 RGD:5128717, RGD:5128711 NCBI chr13:91,727,253...91,737,106
Ensembl chr13:91,730,925...91,737,053 		JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa ISO protein:increased expression:alveolar macrophage RGD PMID:9117017 RGD:5147982 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036 		JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb ISO RGD PMID:20179765 RGD:11344929 NCBI chr13:89,329,298...89,343,916
Ensembl chr13:89,327,794...89,433,815 		JBrowse link
G Fcgr3a Fc fragment of IgG receptor IIIa susceptibility ISO DNA:polymorphism:exon:p.F158V(rs396991)(human) RGD PMID:18199088 RGD:5508449 NCBI chr13:89,385,775...89,396,047
Ensembl chr13:89,385,859...89,396,051 		JBrowse link
G Fga fibrinogen alpha chain treatment IDA RGD PMID:24523826 RGD:11040539 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 ISO ClinVar Annotator: match by term: Asthma ClinVar NCBI chr20:7,976,704...8,097,290
Ensembl chr20:7,976,713...8,019,020 		JBrowse link
G Foxp3 forkhead box P3 treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD PMID:27965764 PMID:29317916, PMID:28944907, PMID:27633092 RGD:38549365, RGD:38548920 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522 		JBrowse link
G Gata3 GATA binding protein 3 ISO
IEP		 RGD PMID:9949310, PMID:18186587 RGD:5128802, RGD:5128803 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681 		JBrowse link
G Gc GC, vitamin D binding protein ISO protein, mRNA:increased expression:bronchoalveolar lavage fluid: RGD PMID:21169467, PMID:21169467 RGD:5509920, RGD:5509920 NCBI chr14:20,267,023...20,302,577
Ensembl chr14:20,266,891...20,302,581 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 susceptibility ISO DNA:polymorphism:promoter: -69C>T (human) RGD PMID:20374258 RGD:5490988 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 resistance
susceptibility		 ISO DNA:deletion: :
CTD Direct Evidence: marker/mechanism		 CTD PMID:16870661 PMID:18988661, PMID:17651144, PMID:21051083, PMID:11075422 RGD:4142509, RGD:5490962, RGD:4140921 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306 		JBrowse link
G Gstm3 glutathione S-transferase mu 3 ISO DNA:polymorphism RGD PMID:17550934, PMID:11470996 RGD:5135038, RGD:5135039 NCBI chr 2:210,685,204...210,688,273
Ensembl chr 2:210,685,197...210,688,272 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 ISO DNA:polymorphism RGD PMID:11470996 PMID:17550934 RGD:5135038 RGD:5135039 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272 		JBrowse link
G Gsto2 glutathione S-transferase omega 2 susceptibility ISO DNA:polymorphism:exon:p. N142D (human) RGD PMID:20374258 RGD:5490988 NCBI chr 1:267,617,517...267,640,455
Ensembl chr 1:271,229,036...271,243,517
Ensembl chr 1:271,229,036...271,243,517 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 severity
susceptibility
disease_progression
no_association		 ISO DNA:polymorphism:exon:p.I105V (rs1695) (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs:exons:p.I105V (rs1695), A114V (rs1138272) (human)
DNA:SNPs:intron,exon:(rs749174), (rs1138272)(human)
DNA:SNPs: :p.I105V, p.A114V (human)
DNA:polymorphism:exon:p.I105V (human)
DNA:SNP: :p.A114V (human)		 CTD PMID:11994713 PMID:16870661 PMID:18988661 PMID:29411558, PMID:10806136, PMID:15693909, PMID:20210814, PMID:20858151, PMID:18057098, PMID:16176403, PMID:18787219, PMID:18709160 RGD:4142526, RGD:5490999, RGD:5490991, RGD:5490985, RGD:4140951, RGD:4142519, RGD:4140946, RGD:4140947 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility ISO DNA:deletion: : RGD PMID:15300848, PMID:21051083, PMID:11075422 RGD:4142539, RGD:5490962, RGD:4140921 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO RGD PMID:20628202 RGD:5128851 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 ISO RGD PMID:17517968 RGD:5135525 NCBI chr10:31,561,838...31,590,624
Ensembl chr10:31,561,895...31,588,943 		JBrowse link
G Hdac2 histone deacetylase 2 ISO mRNA:decreased expression:macrophage: RGD PMID:20538962 RGD:9590321 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198 		JBrowse link
G Hdc histidine decarboxylase ISO associated with Rhinitis;DNA:SNP: :p.E644D (rs2073440) (human) RGD PMID:20608921 RGD:5128884 NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment ISO RGD PMID:18160846 RGD:10402541 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:20084838 RGD:5508450 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654 		JBrowse link
G Hmox1 heme oxygenase 1 severity ISO CTD Direct Evidence: marker/mechanism
mRNA;protein:increased expression:Leukocytes, Mononuclear		 CTD PMID:18048809, PMID:20596599, PMID:16196283 RGD:4145403, RGD:4145408 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456 		JBrowse link
G Hnmt histamine N-methyltransferase no_association
susceptibility		 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by OMIM:600807		 OMIM
CTD
ClinVar		 PMID:9547362 PMID:10752634 PMID:10803682 PMID:15693910 PMID:16205835 PMID:17651147, PMID:15693910, PMID:21040557, PMID:17651147, PMID:10803682, PMID:16205835 RGD:5128888, RGD:5128883, RGD:5128885, RGD:5128881, RGD:5128887 NCBI chr 3:905,111...937,038
Ensembl chr 3:904,765...937,102 		JBrowse link
G Hp haptoglobin ISO RGD PMID:21471098, PMID:21169467 RGD:5144151, RGD:5509920 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11932298 NCBI chr19:37,476,083...37,481,326
Ensembl chr19:37,476,095...37,481,307 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO
IEP		 mRNA:increased expression:aorta (mouse)
CTD Direct Evidence: marker/mechanism
protein:increased secretion:lung (human)
protein:increased expression:lung, serum (rat)		 CTD PMID:17014439 PMID:25003170, PMID:20400685, PMID:20205697, PMID:20953388 RGD:4145444, RGD:4145509, RGD:4145331 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Ifng interferon gamma treatment
resistance		 ISO protein:increased expression:sputum RGD
GAD		 PMID:20817868, PMID:12396623, PMID:15118671, PMID:19542437, PMID:20953328 RGD:4145651, RGD:10755706, RGD:1331525, RGD:5128479, RGD:4145525 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Ifngr1 interferon gamma receptor 1 ISO DNA: SNP: Leu467Pro RGD PMID:21737883, PMID:12851715 RGD:6480255, RGD:6480431 NCBI chr 1:15,062,380...15,080,815
Ensembl chr 1:15,062,432...15,080,907 		JBrowse link
G Ifnl3 interferon, lambda 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22295096 NCBI chr 1:85,236,243...85,237,775
Ensembl chr 1:85,236,243...85,237,775 		JBrowse link
G Ikzf3 IKAROS family zinc finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25256354 NCBI chr10:86,420,757...86,509,454
Ensembl chr10:86,421,582...86,509,454 		JBrowse link
G Il10 interleukin 10 treatment
susceptibility		 ISO
IEP
IGI		 CTD Direct Evidence: marker/mechanism
DNA:polymorphism: :-627C>A (human)
protein:decreased expression:plasma		 CTD PMID:29317916, PMID:20237464, PMID:21998459, PMID:12938145, PMID:20121766, PMID:20644177, PMID:20230687, PMID:20560982 RGD:4140471, RGD:11046261, RGD:4143221, RGD:4140451, RGD:4140459, RGD:4140421, RGD:5131623 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392 		JBrowse link
G Il12a interleukin 12A ISO RGD PMID:17056578, PMID:17548618 RGD:4438438, RGD:4373570 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318 		JBrowse link
G Il12b interleukin 12B severity
susceptibility		 ISO DNA:polymorphisms:introns:
DNA:polymorphisms:promoter, 3'utr:
DNA:polymorphism:promoter		 RGD PMID:15322986, PMID:16210052, PMID:12241719 RGD:1600043, RGD:4145438, RGD:4145428 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085 		JBrowse link
G Il13 interleukin 13 susceptibility
severity
no_association		 ISO
IMP
IDA
IEP		 ClinVar Annotator: match by term: Asthma, susceptibility to
CTD Direct Evidence: marker/mechanism
associated with Dermatitis, Atopic;DNA, protein:SNP, increased expression:promoter, serum:-1112C>T (human)
DNA:polymorphism: :-1512A>C, -1112C>T, 2044G>A (human)
mRNA, protein:increased expression:esophagus, Bronchoalveolar Lavage Fluid
protein:increased expression:serum
DNA:polymorphism:cds:p.R130Q (human)
DNA:polymorphisms:promoters,exon4: rs1881457, rs1800925, rs20541 (human)
DNA:polymorphism: :p. R110Q (human)
DNA:SNP: :c. -646A>G (human)
DNA:polymorphism: :c. 1923C>T (human)
protein:increased expression:sputum
DNA:polymorphism:promoter:c. -1055C>T (human)
DNA:polymorphisms: :rs20541, rs1295685(human)
DNA:polymorphism:3'utr:c.4738G>A (human)
DNA:polymorphism: :c.-1055C>T (human)
DNA:polymorphism: :c. 2044G>A (human)		 ClinVar
OMIM
CTD		 PMID:10699178 PMID:11588017 PMID:11709756 PMID:12847555 PMID:12928861 PMID:15356556 PMID:15483090 PMID:15711639 PMID:15879126 PMID:22867017, PMID:16120094, PMID:23317483, PMID:17006604, PMID:12604708, PMID:20819635, PMID:18222984, PMID:16393274, PMID:11758895, PMID:18258919, PMID:11678850, PMID:19796199, PMID:12091879, PMID:15315330, PMID:17303794, PMID:19575932, PMID:18328894, PMID:16024972, PMID:20484924, PMID:11588017, PMID:20198887, PMID:18341619 RGD:4206706, RGD:8549509, RGD:4892639, RGD:2301686, RGD:4145453, RGD:2307110, RGD:4145508, RGD:4763153, RGD:4145639, RGD:4763761, RGD:4145601, RGD:4145664, RGD:4321828, RGD:4146241, RGD:4145775, RGD:4145777, RGD:4220633, RGD:4145534, RGD:4765128, RGD:4145593, RGD:4145776 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466 		JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 no_association ISO mRNA:increased expression:bronchus
DNA:polymorphisms:promoter, 3' utr:-281T>G, 1365A>G (human)
DNA:polymorphism: :1398A>G (human)
DNA:polymorphism: :1050C>T (human)		 RGD PMID:20383033, PMID:17392323, PMID:18480254, PMID:17006604, PMID:10686479, PMID:11714828 RGD:4892646, RGD:4892650, RGD:4892647, RGD:4892639, RGD:4892655, RGD:4892654 NCBI chr  X:122,724,081...122,783,801
Ensembl chr  X:122,724,129...122,781,479 		JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 ISO mRNA:increased expression:bronchus
protein:increased expression:serum		 RGD PMID:20383033, PMID:21462799, PMID:17885690 RGD:4892646, RGD:8549521, RGD:4892649 NCBI chr  X:118,443,955...118,514,716
Ensembl chr  X:118,443,823...118,513,061 		JBrowse link
G Il15 interleukin 15 no_association ISO DNA:SNPs: :multiple (human) RGD PMID:19133918, PMID:16629787, PMID:11160248, PMID:15843549, PMID:15131572 RGD:5000760, RGD:4984421, RGD:4990462, RGD:5000757, RGD:5000758 NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594 		JBrowse link
G Il16 interleukin 16 no_association
severity		 ISO DNA:SNP:promoter:-295T>C (human)
associated with Rhinitis;protein:increased expression:respiratory system fluid/secretion
protein:increased expression:serum		 RGD PMID:10585533, PMID:16387589, PMID:15784111, PMID:16734115, PMID:12872394 RGD:5024937, RGD:5024934, RGD:5024935, RGD:5024928, RGD:5024930 NCBI chr 1:145,781,923...145,881,538
Ensembl chr 1:145,781,928...145,870,912 		JBrowse link
G Il17a interleukin 17A susceptibility IEP
ISO		 mRNA,protein:increased expression:Leukocytes, Mononuclear, lung, serum
protein:increased expression:sputum
protein:increased expression:alveolar macrophage
DNA:SNP:promoter:rs2275913 (human)		 RGD PMID:18060619, PMID:20351038, PMID:15730730, PMID:18941201, PMID:20437253 RGD:4839043, RGD:4888527, RGD:4889114, RGD:4889152, RGD:4889139 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786 		JBrowse link
G Il17rb interleukin 17 receptor B ISO associated with Picornaviridae Infections RGD PMID:25273095 RGD:39128256 NCBI chr16:6,064,287...6,077,978
Ensembl chr16:6,064,288...6,077,978 		JBrowse link
G Il18 interleukin 18 severity
susceptibility
disease_progression		 ISO DNA:SNPs:Promoter:c. -607C>A (rs1946518), -137G/C (rs187238) (human)
DNA:SNP:promoter:c.and -137G>C (rs187238)(human)
protein:increased expression:serum
DNA:SNP:promoter: c.-380C>G (rs5744247)(human)
DNA:polymorphism: :c. -105A>C (human)		 RGD PMID:17767553, PMID:16433859, PMID:18826499, PMID:11174201, PMID:20497957, PMID:19745201, PMID:18200581 RGD:4889585, RGD:4889923, RGD:4889908, RGD:4889863, RGD:4889898, RGD:4889900, RGD:4889910 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299 		JBrowse link
G Il18r1 interleukin 18 receptor 1 ISO DNA:SNP: :rs3771166 (human)
DNA:SNPs: :multiple (human)		 RGD PMID:19910030, PMID:20860503, PMID:18382474, PMID:11972614, PMID:18774397 RGD:5024945, RGD:5024942, RGD:5024947, RGD:5024948, RGD:5024946 NCBI chr 9:47,184,404...47,217,403
Ensembl chr 9:47,185,443...47,219,175 		JBrowse link
G Il19 interleukin 19 ISO protein:increased expression:serum RGD PMID:15557163 RGD:5037236 NCBI chr13:47,663,592...47,677,869
Ensembl chr13:47,664,080...47,670,407 		JBrowse link
G Il1a interleukin 1 alpha ISO DNA:polymorphisms: : RGD PMID:18763028 RGD:4142802 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086 		JBrowse link
G Il1b interleukin 1 beta susceptibility ISO DNA:polymorphism: :-511C>T (human)
CTD Direct Evidence: marker/mechanism
protein:decreased expression:neutrophil		 CTD PMID:9176529, PMID:18926055, PMID:19842845, PMID:19684087 RGD:4142864, RGD:4142830, RGD:4142836 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 susceptibility
severity		 ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs1420101 (human)
DNA:SNPs:intron:rs1420089, rs1861245,rs1946131 (human)
DNA:SNP: :rs10197862 (human)
DNA:SNP: :rs1041973 (human)		 CTD PMID:19198610 PMID:21150878 PMID:21804549 PMID:24241537 PMID:27472835, PMID:17623648, PMID:17407196, PMID:19179489, PMID:19198610, PMID:19852851, PMID:21150878, PMID:21281963, PMID:11463601 RGD:5144235, RGD:5144245, RGD:5144244, RGD:5144243, RGD:5144242, RGD:5144240, RGD:5144239, RGD:5144237 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170 		JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility
severity		 ISO DNA:SNP: :rs2234678 (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :multiple (human)
DNA:SNPs: :rs447713, rs3087271 (human)
protein:increased expression:plasma
DNA, protein:repeat, decreased expression (human)
DNA:polymorphism:intron (human)		 CTD PMID:9176529, PMID:17107994, PMID:15020290, PMID:16409203, PMID:16724092, PMID:10843772, PMID:11027520, PMID:18926055, PMID:18763028 RGD:4143208, RGD:4143216, RGD:4143163, RGD:4143209, RGD:4143225, RGD:4143224, RGD:4142864, RGD:4142802 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614 		JBrowse link
G Il2 interleukin 2 susceptibility ISO DNA:SNP:promoter:rs2069762(human) RGD PMID:20926789, PMID:16333313 RGD:4889118, RGD:8663473 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854 		JBrowse link
G Il21 interleukin 21 ISO DNA:SNP:exon:5250C>T (human) RGD PMID:18802358 RGD:5147396 NCBI chr 2:123,965,021...123,972,356
Ensembl chr 2:123,965,021...123,972,356 		JBrowse link
G Il22 interleukin 22 treatment
severity		 ISO
IMP		 mRNA:increased expression:blood, mononuclear cell
protein:increased expression:serum		 RGD PMID:21789181, PMID:21998459, PMID:21535180, PMID:21297073 RGD:5147401, RGD:11046261, RGD:5147409, RGD:5147403 NCBI chr 7:61,236,037...61,240,502
Ensembl chr 7:61,236,037...61,240,502 		JBrowse link
G Il23r interleukin 23 receptor ISO RGD PMID:19935773 RGD:5037240 NCBI chr 4:98,203,788...98,306,729
Ensembl chr 4:98,203,958...98,305,173 		JBrowse link
G Il25 interleukin 25 ISO mRNA, protein:increased expression:lung RGD PMID:25273095 RGD:39128256 NCBI chr15:33,594,852...33,599,692
Ensembl chr15:33,596,301...33,599,685 		JBrowse link
G Il27 interleukin 27 susceptibility ISO DNA:SNP: :g.-964A>G (human)
protein:increased expression:sputum		 RGD PMID:17318299, PMID:17878337, PMID:19542437, PMID:20817868 RGD:5128485, RGD:5128491, RGD:5128479, RGD:4145651 NCBI chr 1:198,003,615...198,010,112
Ensembl chr 1:198,003,683...198,008,893 		JBrowse link
G Il27ra interleukin 27 receptor subunit alpha ISO RGD PMID:16081811 RGD:5128496 NCBI chr19:25,151,835...25,163,995
Ensembl chr19:25,149,897...25,164,086 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha IDA
ISO		 RGD PMID:17351063, PMID:20525707, PMID:21377197 RGD:2325990, RGD:5147445, RGD:5147437 NCBI chr17:70,500,672...70,547,929
Ensembl chr17:70,499,083...70,548,071 		JBrowse link
G Il2rb interleukin 2 receptor subunit beta ISO DNA:SNP: :rs2284033 (human) RGD PMID:20860503, PMID:18641329 RGD:5024942, RGD:5147447 NCBI chr 7:119,701,338...119,716,238
Ensembl chr 7:119,701,251...119,716,238 		JBrowse link
G Il3 interleukin 3 susceptibility ISO DNA:SNP: :rs40401(human)
DNA:polymorphism:cds:+79T>C(S27P)(human)		 RGD PMID:24684517, PMID:15372320 RGD:13506914, RGD:13506916 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973 		JBrowse link
G Il33 interleukin 33 treatment
severity		 ISO CTD Direct Evidence: marker/mechanism
associated with viral pneumonia;
associated with fungal infectious disease		 CTD PMID:19198610 PMID:21804549 PMID:24241537 PMID:27472835 PMID:29067999, PMID:28947081, PMID:25746970 RGD:39939002, RGD:39938968 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029 		JBrowse link
G Il4 interleukin 4 treatment
no_association		 ISO
IEP		 DNA:polymorphism (human)
CTD Direct Evidence: marker/mechanism
mRNA, protein:increase expression:leukocyte, serum
protein:increased expression:lung
DNA:SNP: :589C>T (human)
protein:increased expression:respiratory system fluid/secretion
mRNA:increased expression:lung, spleen		 CTD PMID:18357729, PMID:21103062, PMID:24946644, PMID:24450480, PMID:18211752, PMID:20524005, PMID:21354484, PMID:21364926, PMID:21375458 RGD:4889866, RGD:10402799, RGD:10402791, RGD:2317290, RGD:5128560, RGD:5128502, RGD:5128500, RGD:5128557 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531 		JBrowse link
G Il4r interleukin 4 receptor susceptibility
severity
disease_progression		 ISO
ISS		 DNA:mutation:cds:p.Q576R (mouse)
OMIM:600807
DNA:SNPs: :multiple
DNA:polymorphism:cds:p.I50V (human)
DNA:SNPs:cds:p. I75V, Q576R (human)
DNA:polymorphism::-1902G/A (human)
protein:increased secretion:plasma|DNA:polymorphism:promoter:c.-3223C>T (human)
DNA:polymorphism:cds:p.Q576R (human)
DNA:SNPs:cds:p.E375A, Q551R (human)
DNA:polymorphism:cds:p. S478P (human)
DNA:polymorphism:cds:p.Q551R (human)		 MouseDO PMID:19770271, PMID:17823973, PMID:18425216, PMID:12133990, PMID:20868478, PMID:11398072, PMID:15479272, PMID:12940513, PMID:17170387, PMID:11709756, PMID:20605987, PMID:20953944, PMID:16917945, PMID:17586032 RGD:4890003, RGD:4890347, RGD:4890346, RGD:4890404, RGD:4890387, RGD:4890406, RGD:4890351, RGD:4890402, RGD:4890349, RGD:4890024, RGD:5128553, RGD:5128514, RGD:4890352, RGD:4890348 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220 		JBrowse link
G Il5 interleukin 5 treatment
disease_progression		 IDA
ISO
IEP
IMP		 CTD Direct Evidence: marker/mechanism
protein:increased expression:lungs, respiratory system fluid/secretion
protein: increased levels: sputum
protein:increased expression:respiratory system fluid/secretion
DNA:polymorphism:promoter:-703C>T (human)		 CTD PMID:7540862 PMID:23266719, PMID:17074272, PMID:25008888, PMID:11159041, PMID:22085848, PMID:22186238, PMID:15626484, PMID:15502111, PMID:9182686, PMID:18629290, PMID:9493449, PMID:19947994 RGD:4145461, RGD:11354973, RGD:5687189, RGD:5687144, RGD:5687140, RGD:4890947, RGD:4890948, RGD:4890963, RGD:4890940, RGD:4890962, RGD:4890938 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587 		JBrowse link
G Il5ra interleukin 5 receptor subunit alpha ISO DNA:SNP: :c.25091G>A (human)
DNA:SNPs (human)		 RGD PMID:20513521, PMID:20592918, PMID:17276963, PMID:10848907, PMID:10224351, PMID:16217591 RGD:5128625, RGD:5128614, RGD:5128617, RGD:5128627, RGD:5128623, RGD:5128626 NCBI chr 4:138,796,165...138,834,164
Ensembl chr 4:138,795,327...138,830,117 		JBrowse link
G Il6 interleukin 6 ISO
IEP		 CTD Direct Evidence: marker/mechanism
associated with Hypersensitivity;protein:increased expression:sputum
protein:increased expression:lung		 CTD PMID:29902480, PMID:21115736, PMID:20840469, PMID:20816188, PMID:20685386 RGD:5128630, RGD:4143265, RGD:4143266, RGD:4143271 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Il6r interleukin 6 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:29902480, PMID:17496315, PMID:21115736 RGD:5128662, RGD:5128630 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628 		JBrowse link
G Il9 interleukin 9 ISO protein:increased expression:respiratory system fluid/secretion
protein:increased expression:sputum, macrophage, cytoplasm		 RGD PMID:12153980, PMID:17446528, PMID:15531759, PMID:15303135, PMID:21356110 RGD:5128700, RGD:5128686, RGD:5128690, RGD:5128691, RGD:5128707 NCBI chr17:8,558,827...8,561,950
Ensembl chr17:8,558,827...8,561,950 		JBrowse link
G Il9r interleukin 9 receptor ISO RGD PMID:10629460 RGD:5128704 NCBI chr10:15,697,216...15,708,684
Ensembl chr10:15,696,824...15,710,423 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 susceptibility ISO ClinVar Annotator: match by OMIM:611064
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:17503328 NCBI chr 7:64,922,830...64,982,224
Ensembl chr 7:64,923,615...64,982,281 		JBrowse link
G Irf1 interferon regulatory factor 1 no_association
susceptibility		 ISO DNA:polymorphisms:promoter, cds:-300G>T, 4396A>G, 6355G>A (human)
protein:increased expression:respiratory tract epithelium
DNA:repeat:intron (human)		 RGD PMID:11069564, PMID:10225979, PMID:16961714 RGD:5128726, RGD:5128723, RGD:5128724 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531 		JBrowse link
G Irf3 interferon regulatory factor 3 ISO RGD PMID:20673978 RGD:5128793 NCBI chr 1:100,992,244...100,997,202
Ensembl chr 1:100,992,405...100,997,198 		JBrowse link
G Itgb3 integrin subunit beta 3 ISO DNA:SNPs: : RGD PMID:17556058 RGD:5037230 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410 		JBrowse link
G Itgb6 integrin subunit beta 6 ISS OMIM:600807 MouseDO NCBI chr 3:46,652,624...46,775,362
Ensembl chr 3:46,652,623...46,726,958 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 IDA RGD PMID:21777465 RGD:5147661 NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748 		JBrowse link
G Kdr kinase insert domain receptor ISO associated with Rhinitis,Allergic,Seasonal;protein:increased expression:nasal cavity of mucosa: RGD PMID:20921519, PMID:17651148 RGD:5684385, RGD:8551771 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183 		JBrowse link
G Kif3a kinesin family member 3a ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr10:38,918,705...38,953,958
Ensembl chr10:38,918,748...38,952,785 		JBrowse link
G Krt19 keratin 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15478392 NCBI chr10:88,055,843...88,060,560
Ensembl chr10:88,055,841...88,060,561 		JBrowse link
G Lep leptin ISO protein:increased expression:plasma RGD PMID:19705789 RGD:5128781 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818 		JBrowse link
G Lgals3 galectin 3 treatment ISO RGD PMID:16424226 RGD:9685213 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537 		JBrowse link
G Lta lymphotoxin alpha susceptibility
no_association		 ISO DNA:polymorphisms:promoter
DNA:polymorphism:intron		 RGD PMID:15969671, PMID:18947013, PMID:12530118, PMID:17536219 RGD:4143373, RGD:4143370, RGD:4143254, RGD:4143371 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677 		JBrowse link
G Lta4h leukotriene A4 hydrolase IEP mRNA:increased expression:lung, cerebral cortex (rat) RGD PMID:15715933 RGD:2316607 NCBI chr 7:34,288,333...34,320,243
Ensembl chr 7:34,288,365...34,320,235 		JBrowse link
G Ltc4s leukotriene C4 synthase ISO OMIM NCBI chr10:35,736,486...35,743,088
Ensembl chr10:35,737,664...35,739,625 		JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO associated with Bronchiolitis;DNA:polymorphism:exon:
DNA:SNP:cds:p.G54D(human)		 RGD PMID:22512728, PMID:22674410 RGD:8693709, RGD:12910828 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962 		JBrowse link
G Mefv MEFV innate immuity regulator, pyrin susceptibility ISO DNA:mutations:exons RGD PMID:18219832 RGD:5129186 NCBI chr10:12,045,813...12,056,229
Ensembl chr10:12,046,541...12,056,311 		JBrowse link
G Mif macrophage migration inhibitory factor severity ISO
IDA		 protein:increased expression:bronchoalveolar lavage fluid
DNA:SNP:promoter:rs755622(human)
DNA:repeats:promoter		 RGD PMID:9637721, PMID:17373669, PMID:19317738, PMID:16186482, PMID:16455830 RGD:4891043, RGD:4891035, RGD:4891059, RGD:4891052, RGD:1641985 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859 		JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24469321 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591 		JBrowse link
G Mmp10 matrix metallopeptidase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16926187 NCBI chr 8:5,734,348...5,742,243
Ensembl chr 8:5,734,348...5,742,243 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO
IEP		 protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
protein:increased expression:lung
DNA:SNP: : rs2664538(human)
mRNA, protein:increased expression:lung		 CTD PMID:11742282 PMID:15131573, PMID:21439806, PMID:19361849, PMID:20181264, PMID:16191269, PMID:19940022 RGD:5129204, RGD:5129687, RGD:5130859, RGD:2325953, RGD:5129522 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520 		JBrowse link
G Mpo myeloperoxidase susceptibility ISO DNA:polymorphism: :−463G > A (human)
protein:increased expression:serum		 RGD PMID:19544176, PMID:10731862 RGD:5130989, RGD:5130994 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260 		JBrowse link
G Ms4a2 membrane spanning 4-domains A2 susceptibility ISO DNA:SNPs:multiple:, rs573790, rs2583476, rs569108
DNA:SNPs: : rs556917, rs502581, rs502419 (human)
DNA:SNP: : -109C>T (human)
Atopy and bronchial hyperresponsiveness, OMIM:147050		 RGD PMID:19218813, PMID:21320344, PMID:19862939, PMID:8817330 RGD:5131151, RGD:5131149, RGD:5131092, RGD:1599903 NCBI chr 1:227,957,363...227,965,312
Ensembl chr 1:227,957,302...227,965,386 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO DNA:transition:cds:g.677C>T (human) RGD PMID:20456312 RGD:4891145 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910 		JBrowse link
G Muc1 mucin 1, cell surface associated ISO protein:increased expression:serum RGD PMID:11802251 RGD:5131281 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874 		JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming ISO associated with hypersensitivity RGD PMID:11062147, PMID:14594655 RGD:5131178, RGD:7349354 NCBI chr 1:214,663,929...214,693,197 JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming treatment IEP
ISO		 mRNA,protein:increased expression:lung
mRNA, protein:increased expression:lung		 RGD PMID:17590487, PMID:21549818, PMID:21780541, PMID:14594655, PMID:17698377 RGD:2324962, RGD:7364729, RGD:7349407, RGD:7349354, RGD:5131204 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming ISO protein:altered expression:sputum RGD PMID:11802783, PMID:11587997 RGD:5131252, RGD:7364763 NCBI chr 1:214,778,459...214,811,237
Ensembl chr 1:214,778,496...214,810,720 		JBrowse link
G Myb MYB proto-oncogene, transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chr 1:16,658,178...16,690,135
Ensembl chr 1:16,659,442...16,687,817 		JBrowse link
G Mylk myosin light chain kinase ISO RGD PMID:17472811 RGD:4891492 NCBI chr11:69,013,060...69,260,039
Ensembl chr11:69,013,050...69,223,158 		JBrowse link
G Nat2 N-acetyltransferase 2 susceptibility ISO DNA:polymorphisms: :
Asthma, Aspirin-Induced; DNA:polymorphism: :		 RGD PMID:16924569, PMID:20602614 RGD:5131606, RGD:5131600 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 severity ISO mRNA:increased expression:bronchoalveolar lavage cell, peripheral blood mononuclear cell (human) RGD PMID:21514635 RGD:6893376 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Ngf nerve growth factor severity ISO protein:increased expression:blood, eosinophil
protein:increased expression:lung, serum		 RGD PMID:12752594, PMID:17164945, PMID:17497413, PMID:11737043 RGD:4891122, RGD:4891108, RGD:4891068, RGD:4891123 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453 		JBrowse link
G Ngfr nerve growth factor receptor ISO RGD PMID:16603479, PMID:12540484 RGD:5144070, RGD:5144072 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 susceptibility ISO DNA:SNP: :rs2075817 (human)
DNA:insertion:cds:		 RGD PMID:16918516, PMID:15718249 RGD:5131519, RGD:5131518 NCBI chr 4:85,123,965...85,175,206
Ensembl chr 4:85,123,960...85,174,951 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 susceptibility ISO DNA:polymorphisms:intron, exon/3'UTR (rs1077861, rs3135500) (human) RGD PMID:16008671, PMID:21051079 RGD:5131477, RGD:5508757 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492 		JBrowse link
G Nos1 nitric oxide synthase 1 susceptibility ISO DNA:repeats:exon
DNA:repeats:intron
DNA:repeats: :		 RGD PMID:10833424, PMID:14767694, PMID:10673365, PMID:20609134 RGD:5132860, RGD:5132615, RGD:5132869, RGD:5132863 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341 		JBrowse link
G Nos2 nitric oxide synthase 2 disease_progression
severity
no_association		 ISO
IEP
IMP		 protein:increased expression:lung, bronchoalveolar lavage fluid
CTD Direct Evidence: marker/mechanism
protein:increased expression, increased activity:lung (rat)
DNA:repeats:promoter
associated with Rhinitis, Allergic, Seasonal; protein:increased expression:nasal mucosa
DNA:SNP:exon:p.S608L (human)
DNA:repeats:promoter, introns (human)
mRNA:increased expression:monocyte
DNA:repeat:promoter		 CTD PMID:19800904, PMID:17161822, PMID:21847581, PMID:18714530, PMID:18254476, PMID:17177683, PMID:17189532, PMID:20842520, PMID:16703578, PMID:16540403, PMID:20841959 RGD:4891927, RGD:5509073, RGD:4891508, RGD:4891910, RGD:4891925, RGD:4891924, RGD:4891419, RGD:4891953, RGD:4891957, RGD:4891480 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility ISO DNA:snps, repeat, haplotype:promoter, introns, exons:multiple (human)
DNA:polymorphisms:promoter:c. -786C>T, -691C>T (human)
DNA:repeats:intron		 RGD PMID:18486767, PMID:16837812, PMID:16081038 RGD:4892053, RGD:4892058, RGD:4892062 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410 		JBrowse link
G Npsr1 neuropeptide S receptor 1 susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by OMIM:608584		 CTD
OMIM
ClinVar		 PMID:15073379 PMID:15710598 PMID:15764725 PMID:16926187, PMID:17702965, PMID:18285428, PMID:15073379 RGD:4891923, RGD:4891922, RGD:4891921 NCBI chr 8:25,246,174...25,483,582
Ensembl chr 8:25,246,292...25,482,647 		JBrowse link
G Npy neuropeptide Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:9731035 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 susceptibility ISO DNA:SNP:exon:c. 609C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:c.609C>T (human)		 CTD PMID:20049212, PMID:19027876, PMID:19591959 RGD:5135006, RGD:5135005 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 treatment
susceptibility
severity		 ISO
IDA		 DNA:polymorphism:intron
protein:increased expression, decreased activity:leukocyte, mononuclear		 RGD PMID:18396779, PMID:20727335, PMID:21113676, PMID:18799869, PMID:15295049 RGD:4892328, RGD:7174728, RGD:4892568, RGD:4892594, RGD:4892609 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647 		JBrowse link
G Ntf3 neurotrophin 3 ISO protein:increased expression:lung, serum RGD PMID:11737043, PMID:17497413 RGD:4891123, RGD:4891068 NCBI chr 4:158,636,883...158,705,886
Ensembl chr 4:158,636,884...158,705,886 		JBrowse link
G Ntf4 neurotrophin 4 ISO protein:increased expression:lung, serum RGD PMID:17497413 RGD:4891068 NCBI chr 1:101,405,314...101,408,145
Ensembl chr 1:101,405,314...101,408,145 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 ISO
IEP		 mRNA:increased expression:lung: RGD PMID:20934630, PMID:16708804 RGD:5684766, RGD:5684772 NCBI chr 2:187,143,568...187,160,373
Ensembl chr 2:187,143,568...187,160,373 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21150878 PMID:25256354 NCBI chr10:86,545,910...86,554,478
Ensembl chr10:86,547,339...86,554,478 		JBrowse link
G P2ry12 purinergic receptor P2Y12 ISO RGD PMID:22010907, PMID:19822647 RGD:6480532, RGD:6480533 NCBI chr 2:149,440,807...149,482,592
Ensembl chr 2:149,441,598...149,444,548 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased activation:lung, blood, mononuclear cell		 CTD PMID:18261157, PMID:12594058, PMID:26205779, PMID:26205779 RGD:5683910, RGD:11073727, RGD:11073727 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716 		JBrowse link
G Pdcd1 programmed cell death 1 treatment ISO associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chr 9:101,305,742...101,319,937
Ensembl chr 9:101,307,764...101,319,845 		JBrowse link
G Pde4b phosphodiesterase 4B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 5:121,759,236...122,136,814
Ensembl chr 5:121,952,977...122,136,814 		JBrowse link
G Pde4d phosphodiesterase 4D ISO CTD Direct Evidence: marker/mechanism CTD PMID:19426955 PMID:21611147 NCBI chr 2:40,219,999...41,468,551
Ensembl chr 2:40,554,146...41,464,264 		JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO
IMP		 protein: increased expression RGD PMID:21216974, PMID:21216974 RGD:6483071, RGD:6483071 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741 		JBrowse link
G Pgf placental growth factor ISO RGD PMID:22268141 RGD:6483605 NCBI chr 6:108,994,016...109,004,598
Ensembl chr 6:108,994,018...109,004,598 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma ISO RGD PMID:18754810 RGD:6482695 NCBI chr 6:51,465,696...51,501,234
Ensembl chr 6:51,465,908...51,498,337 		JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 IMP RGD PMID:18188456 RGD:8693422 NCBI chr 8:21,669,236...21,680,615
Ensembl chr 8:21,669,236...21,680,615 		JBrowse link
G Pla2g4a phospholipase A2 group IVA IEP RGD PMID:15557087 RGD:1642462 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693 		JBrowse link
G Pla2g7 phospholipase A2 group VII susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Asthma and atopy, susceptibility to		 OMIM
CTD
ClinVar		 PMID:10733466 PMID:15115767, PMID:10733466 RGD:1581025 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013 		JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604, PMID:18519237 RGD:4892037 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:22205926 NCBI chr10:37,534,449...37,554,861
Ensembl chr10:37,535,871...37,554,664 		JBrowse link
G Prf1 perforin 1 ISO
IDA		 RGD PMID:22250087, PMID:21426642 RGD:6482815, RGD:6482818 NCBI chr20:30,915,294...30,920,804
Ensembl chr20:30,915,213...30,921,382 		JBrowse link
G Prg2 proteoglycan 2 severity
disease_progression
no_association		 ISO mRNA:increased expression:eosinophil:
associated with cough;protein:increased expression:sputum:
associated with viral infection;mRNA:increased expression:sputum:		 RGD PMID:16982448, PMID:22022864, PMID:24450586, PMID:11067904 RGD:13506941, RGD:13506944, RGD:13506943, RGD:13506942 NCBI chr 3:72,385,678...72,389,245
Ensembl chr 3:72,385,666...72,389,276 		JBrowse link
G Prmt1 protein arginine methyltransferase 1 IEP mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr 1:100,971,132...100,980,411
Ensembl chr 1:100,971,273...100,980,340 		JBrowse link
G Prmt2 protein arginine methyltransferase 2 IEP mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chr20:13,154,513...13,212,613
Ensembl chr20:13,156,241...13,212,606 		JBrowse link
G Prmt3 protein arginine methyltransferase 3 IEP mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr 1:105,113,595...105,200,253
Ensembl chr 1:105,113,595...105,200,470 		JBrowse link
G Prmt5 protein arginine methyltransferase 5 IEP mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chr15:33,156,508...33,165,893
Ensembl chr15:33,156,492...33,165,895 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:26381519 RGD:11099992 NCBI chr18:24,918,402...24,928,822
Ensembl chr18:24,918,398...24,929,091 		JBrowse link
G Pten phosphatase and tensin homolog ISO CTD Direct Evidence: therapeutic CTD PMID:17982072 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832 		JBrowse link
G Ptgdr prostaglandin D2 receptor susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD		 NCBI chr15:19,195,606...19,196,508 JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 ISO Aspirin exacerbated asthma
CTD Direct Evidence: therapeutic		 CTD PMID:27103662, PMID:19796209, PMID:19392992, PMID:18757520 RGD:5135020, RGD:5135019, RGD:5135018 NCBI chr 1:226,976,455...226,995,641
Ensembl chr 1:226,993,250...226,994,849 		JBrowse link
G Ptger3 prostaglandin E receptor 3 treatment IMP RGD PMID:23221044 RGD:10043366 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 susceptibility
severity		 ISO
IEP		 mRNA:increased expression:lung
DNA:SNP: :8473T>C (human)
mRNA, protein:increased expression:lung:
DNA:SNP: :rs689465 (human)		 RGD PMID:19878559, PMID:15316498, PMID:17573729, PMID:18097056, PMID:18489027, PMID:19342146, PMID:19862936 RGD:5135514, RGD:5143931, RGD:5143923, RGD:5135534, RGD:5135526, RGD:5135522, RGD:5135515 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Rad50 RAD50 double strand break repair protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr10:39,002,130...39,054,042
Ensembl chr10:39,001,498...39,054,142 		JBrowse link
G Rhoa ras homolog family member A IEP RGD PMID:18391481 RGD:2298885 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167 		JBrowse link
G Rnase3 ribonuclease A family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8874658 PMID:12153692 PMID:12587966 NCBI chr15:28,216,744...28,217,614
Ensembl chr15:28,216,744...28,217,614 		JBrowse link
G RT1-B RT1 class II, locus B susceptibility ISO DNA:polymorphisms: : RGD PMID:21814517 RGD:13506911
G RT1-Ba RT1 class II, locus Ba ISO DNA:polymorphisms (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism (human) 		CTD PMID:10792356, PMID:12890388, PMID:10051703, PMID:11802952, PMID:19052351 RGD:5147799, RGD:1331670, RGD:5147831, RGD:5147617 NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721 		JBrowse link
G RT1-Bb RT1 class II, locus Bb susceptibility
disease_progression
no_association		 ISO Alternaria sensitive asthma
DNA:polymorphisms: :
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms (human)		 CTD PMID:10792356, PMID:20298583, PMID:20159242, PMID:20214848, PMID:23331206, PMID:11802952, PMID:12890388, PMID:19052351 RGD:4144113, RGD:13506913, RGD:4144181, RGD:13506906, RGD:5147831, RGD:5147799, RGD:5147617 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711 		JBrowse link
G RT1-Da RT1 class II, locus Da susceptibility ISO DNA:polymorphisms: : RGD PMID:20159242 RGD:13506913 NCBI chr20:4,127,644...4,132,616
Ensembl chr20:4,127,644...4,132,616 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 susceptibility
no_association
severity		 ISO DNA:polymorphisms: :
CTD Direct Evidence: marker/mechanism
DNA:polymorphism (human) 		CTD PMID:16792590, PMID:19528258, PMID:20159242, PMID:23331206, PMID:10051703, PMID:19439981, PMID:20486920, PMID:20214848 RGD:4144196, RGD:13506913, RGD:13506906, RGD:1331670, RGD:5147663, RGD:5147607, RGD:4144181 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190 		JBrowse link
G RT1-Ha RT1 class II, locus Ha susceptibility ISO DNA:polymorphism: : RGD PMID:21814517 RGD:13506911 NCBI chr20:3,875,478...3,885,140
Ensembl chr20:3,875,706...3,881,461 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 ISO RGD PMID:15611928 RGD:5144118 NCBI chr20:1,814,661...1,833,033
Ensembl chr20:1,814,661...1,818,800 		JBrowse link
G Runx1 RUNX family transcription factor 1 ISO DNA:SNPs: :multiple RGD PMID:21803869 RGD:6482835 NCBI chr11:32,765,147...33,003,061
Ensembl chr11:32,769,165...33,003,021 		JBrowse link
G Runx3 RUNX family transcription factor 3 ISS OMIM:600807 MouseDO NCBI chr 5:153,507,093...153,531,137
Ensembl chr 5:153,507,093...153,531,137 		JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 susceptibility IEP
ISO		 mRNA,protein:decreased expression:bronchial alveolar lavage fluid, lung:
ClinVar Annotator: match by term: Asthma, susceptibility to
associated with allergic rhinitis; DNA:SNP:exon:38G>A (human)
protein:decreased expression:serum		 ClinVar PMID:9550363, PMID:12921604, PMID:21255142, PMID:15467329 RGD:5144052, RGD:5144226, RGD:5144148 NCBI chr 1:225,279,698...225,283,246
Ensembl chr 1:225,279,676...225,283,326 		JBrowse link
G Scgb3a2 secretoglobin, family 3A, member 2 susceptibility
severity
no_association		 ISO DNA:SNP:promoter:-112G>A (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by OMIM:600807
mRNA,protein:decreased expression:;lung
protein:increased expression:sputum		 CTD
OMIM
ClinVar		 PMID:11813133, PMID:11813133, PMID:15531759, PMID:16456148, PMID:17218572, PMID:18089940, PMID:18201431 RGD:5144229, RGD:5128690, RGD:5144233, RGD:5144232, RGD:5144231, RGD:5144230 NCBI chr18:38,292,822...38,295,744
Ensembl chr18:38,292,701...38,295,831 		JBrowse link
G Sell selectin L ISO RGD PMID:21437035, PMID:21515793 RGD:5685685, RGD:5685696 NCBI chr13:82,369,820...82,387,774
Ensembl chr13:82,369,493...82,387,631 		JBrowse link
G Serpina1 serpin family A member 1 IEP Fisher rats, shown to exhibit hyperactive airway responses at 14 days of age, had higher transcript and protein levels of Serpina1 than same age Brown Norway rats. RGD PMID:20118217 RGD:5131869 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265 		JBrowse link
G Serpine1 serpin family E member 1 susceptibility
no_association
severity		 IEP
ISO		 protein:increased activity, increased expression:plasma, lung
DNA:polymorphism:promoter:rs1799768 (human)
protein:increased expression:plasma		 RGD PMID:18594148, PMID:19063817, PMID:19604112, PMID:19703828 RGD:4144836, RGD:4144832, RGD:4144833, RGD:4144831 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482 		JBrowse link
G Sftpa1 surfactant protein A1 IEP
ISO		 protein:decreased expression:lung, Clara cell, pneumocyte
mRNA, protein:increased expression:lung		 RGD PMID:15816355, PMID:16629790, PMID:18802356, PMID:18926058 RGD:4143398, RGD:4143462, RGD:4143516, RGD:4143289 NCBI chr16:18,716,019...18,719,404
Ensembl chr16:18,716,019...18,719,403 		JBrowse link
G Sftpb surfactant protein B ISO
IEP		 protein:increased expression:lung
mRNA, protein:decreased expression:lung
protein:decreased expression:lung, Clara cell		 RGD PMID:16629790, PMID:11472974, PMID:18926058, PMID:15816355 RGD:4143462, RGD:4143465, RGD:4143289, RGD:4143398 NCBI chr 4:100,166,855...100,175,941
Ensembl chr 4:100,166,863...100,175,938 		JBrowse link
G Sftpc surfactant protein C susceptibility ISO mRNA, protein:decreased expression:lung
protein:increased expression:lung
DNA:polymorphism: :p.A53T (human)		 RGD PMID:11472974, PMID:16629790, PMID:19910179 RGD:4143465, RGD:4143462, RGD:4144063 NCBI chr15:52,211,538...52,214,480
Ensembl chr15:52,211,544...52,214,616 		JBrowse link
G Sftpd surfactant protein D ISO
IEP		 protein:increased expression:lung
associated with Bronchitis;protein:increased expression:lung
mRNA, protein:increased expression:lung		 RGD PMID:16629790, PMID:11472974, PMID:18266831, PMID:16839409, PMID:18802356 RGD:4143462, RGD:4143465, RGD:4143517, RGD:4143508, RGD:4143516 NCBI chr16:18,753,535...18,766,100
Ensembl chr16:18,745,458...18,766,174 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 ISO RGD PMID:12847242 RGD:5684966 NCBI chr 9:81,655,590...81,666,697
Ensembl chr 9:81,655,629...81,666,706 		JBrowse link
G Slc18a3 solute carrier family 18 member A3 IEP RGD PMID:17328924 RGD:5686690 NCBI chr16:8,682,668...8,685,529
Ensembl chr16:8,682,669...8,685,529 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 IEP RGD PMID:17328924 RGD:5686690 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655 		JBrowse link
G Slc5a7 solute carrier family 5 member 7 IEP mRNA:decreased expression:lung RGD PMID:17328924 RGD:5686690 NCBI chr 9:5,294,377...5,330,822
Ensembl chr 9:5,294,381...5,330,815 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 susceptibility ISO DNA:repeat:intron (human) RGD PMID:19806585 RGD:4889460 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463 		JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22867017 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862 		JBrowse link
G Sod2 superoxide dismutase 2 ISO RGD PMID:15743779 RGD:1581231 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 treatment IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:28807506, PMID:18211752 RGD:2317290 NCBI chr 9:54,340,649...54,457,753
Ensembl chr 9:54,287,541...54,484,533 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 treatment IEP
IDA		 RGD PMID:19087723, PMID:16083555 RGD:7244151, RGD:7244153 NCBI chr 7:70,946,228...70,963,542
Ensembl chr 7:70,946,228...70,964,484 		JBrowse link
G Tac1 tachykinin, precursor 1 ISO protein:increased expression:lung RGD PMID:11031342 RGD:5147836 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819 		JBrowse link
G Tacr1 tachykinin receptor 1 IEP
ISO		 protein:increased expression:lung
mRNA:increased expression:lung
mRNA,protein:increased expression:lung		 RGD PMID:17392578, PMID:8240667, PMID:16409782 RGD:2304339, RGD:5147645, RGD:5147475 NCBI chr 4:113,247,236...113,416,139
Ensembl chr 4:113,247,795...113,414,504 		JBrowse link
G Tacr2 tachykinin receptor 2 ISO DNA:SNP:cds:p.G231E (human) RGD PMID:20175803, PMID:19880429 RGD:5147640, RGD:5147641 NCBI chr20:31,892,515...31,905,153
Ensembl chr20:31,892,515...31,905,153 		JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member susceptibility ISO DNA:polymorphism: : RGD PMID:12640628 RGD:5147845 NCBI chr20:3,979,302...3,989,669
Ensembl chr20:3,979,035...3,989,669 		JBrowse link
G Tbx21 T-box transcription factor 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15806396 NCBI chr10:85,032,799...85,049,331
Ensembl chr10:85,032,799...85,049,331 		JBrowse link
G Tbxa2r thromboxane A2 receptor susceptibility
severity		 ISO DNA:polymorphism:cds:924T>C(human) GAD
RGD		 PMID:15118671, PMID:12000493, PMID:15805995 RGD:1331525, RGD:11059535, RGD:11059534 NCBI chr 7:11,253,153...11,259,233
Ensembl chr 7:11,253,180...11,257,977 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 onset
no_association		 ISO
IEP		 DNA:SNP: :-509C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs:promoter, exon:multiple (human)
DNA:SNP:cds:915G>C (human)
mRNA:increased expression:lung
protein:increased expression:serum
DNA:polymorphisms: :multiple (human)
DNA:polymorphism: :-509C>T (human)		 CTD PMID:16365456 PMID:19138248, PMID:17673695, PMID:18366906, PMID:19096005, PMID:19620629, PMID:19046298, PMID:20485865, PMID:19317336, PMID:19136038, PMID:18711258, PMID:19222424, PMID:19533439 RGD:4145295, RGD:4145280, RGD:4145143, RGD:4145132, RGD:4145142, RGD:4145113, RGD:4145139, RGD:4145144, RGD:4143443, RGD:4145299, RGD:4145297 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Thbd thrombomodulin ISO RGD PMID:20709825 RGD:5684984 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16926187 NCBI chr 7:23,543,125...23,594,170
Ensembl chr 7:23,544,215...23,594,133 		JBrowse link
G Tlr1 toll-like receptor 1 susceptibility ISO DNA:SNP (human) RGD PMID:18547625 RGD:4889528 NCBI chr14:45,062,662...45,065,014
Ensembl chr14:45,062,662...45,081,991 		JBrowse link
G Tlr10 toll-like receptor 10 susceptibility ISO DNA:SNP (human) RGD PMID:18547625 RGD:4889528 NCBI chr14:45,073,652...45,082,242 JBrowse link
G Tlr2 toll-like receptor 2 susceptibility
severity		 ISO DNA:SNP: :596T>C (human)
DNA:polymorphism:cds:p.R753Q(human)
DNA:SNP: :rs3804100 (human)
DNA:SNP: :rs7656411 (human)
DNA:SNP: :rs4696480 (human)		 RGD PMID:19096003, PMID:22402138, PMID:19148143, PMID:18202345, PMID:20815312, PMID:20685742, PMID:18787777 RGD:4144228, RGD:7800732, RGD:2312679, RGD:4145343, RGD:4145352, RGD:4144171, RGD:4145334 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061 		JBrowse link
G Tlr3 toll-like receptor 3 no_association ISO
IMP		 Asthma, Virus-Induced; mRNA:increased expression:sputum (human)
DNA:snp:cds:p.L412F (human)		 RGD PMID:21129050, PMID:17434873, PMID:14987294, PMID:17610940, PMID:21364926 RGD:5129226, RGD:5129478, RGD:5129493, RGD:5129475, RGD:5128500 NCBI chr16:50,016,466...50,031,011
Ensembl chr16:50,016,857...50,031,214 		JBrowse link
G Tlr4 toll-like receptor 4 susceptibility
no_association
severity		 ISO DNA:Polymorphism:cds:p.D299G (human)
DNA:SNPs::
protein:decreased expression:leukocytes, mononuclear
DNA:SNPs: :rs10983755, rs1927914 (human)
DNA:polymorphisms:cds:c.896A>G, 1196C>T (human)		 RGD PMID:15356557, PMID:20628601, PMID:20685742, PMID:19067129, PMID:19330007, PMID:19159017, PMID:16266379 RGD:4144817, RGD:4144176, RGD:4144171, RGD:4144190, RGD:4144141, RGD:4144188, RGD:4144198 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052 		JBrowse link
G Tlr6 toll-like receptor 6 susceptibility ISO DNA:SNP (human)
DNA:SNP: :p.S249P (human)		 RGD PMID:18547625, PMID:15266299 RGD:4889528, RGD:4889538 NCBI chr14:45,024,351...45,041,188
Ensembl chr14:45,024,351...45,046,446 		JBrowse link
G Tlr9 toll-like receptor 9 no_association
susceptibility
severity		 ISO DNA:SNP:promoter:g.-1237T>C rs5743836 (human)
DNA:snp:promoter:g.-1237T>C rs5743836 (human)
protein:increased expression:peripheral blood mononuclear cell (human)		 RGD PMID:21324137, PMID:18312481, PMID:20016192, PMID:20072849 RGD:5130712, RGD:4144208, RGD:5129104, RGD:4889523 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171 		JBrowse link
G Tnc tenascin C ISO CTD Direct Evidence: marker/mechanism
DNA:SNPs: :multiple (human)
protein:increased expression:bronchus basement membrane
DNA:SNP:exon:p.L1677I (human)		 CTD PMID:16115819, PMID:17125141, PMID:18305139, PMID:9310019, PMID:16115819 RGD:4889565, RGD:4889589, RGD:4889572, RGD:4889569 NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671 		JBrowse link
G Tnf tumor necrosis factor susceptibility
no_association		 ISO DNA:polymorphism:promoter: c. -308A>G (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by OMIM:600807
associated with obesity; DNA:polymorphism:promoter
DNA:polymorphisms:: rs1799964, rs1799724 (human)
DNA:polymorphisms: :
associated with nasal polys; protein:increased expression:nose
DNA:polymorphism:promoter:c.-863C > A (human)		 OMIM
CTD
ClinVar		 PMID:8056188 PMID:9818939 PMID:10450718 PMID:11261930 PMID:11506397 PMID:11826025 PMID:11896460 PMID:12356572 PMID:12485196 PMID:12746914 PMID:14681301 PMID:14718719 PMID:16418737 PMID:16456144 PMID:16865291 PMID:17450233 PMID:20049212,