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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Penile Neoplasms
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Accession:DOID:9003196 term browser browse the term
Definition:Cancers or tumors of the PENIS or of its component tissues.
Synonyms:exact_synonym: neoplasm of penis;   penile neoplasm;   penile tumor;   penis neoplasm;   penis neoplasms
 primary_id: MESH:D010412
 xref: EFO:1001094;   NCI:C3317


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Penile Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hras HRas proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18355852 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18355852 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:18355852 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9626339 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
penile benign neoplasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd1 cyclin D1 ISO protein:increased expression:nucleus RGD PMID:17695500 RGD:2289129 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ptges prostaglandin E synthase ISO protein:increased expression:penis, skin RGD PMID:14871981 RGD:2300087 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Top2a DNA topoisomerase II alpha severity ISO RGD PMID:18489530 RGD:2315128 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19100
    disease of anatomical entity 18440
      reproductive system disease 3178
        male reproductive system disease 2035
          penile disease 131
            Penile Neoplasms 7
              penile benign neoplasm 3
              penile cancer + 0
Path 2
Term Annotations click to browse term
  disease 19100
    disease of anatomical entity 18440
      Urogenital Diseases 5376
        Male Urogenital Diseases 2035
          male reproductive system disease 2035
            penile disease 131
              Penile Neoplasms 7
                penile benign neoplasm 3
                penile cancer + 0
paths to the root