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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(5alpha)-cholestan-3beta-ol
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Accession:CHEBI:86570 term browser browse the term
Definition:A cholestanoid that is (5alpha)-cholestane substituted by a beta-hydroxy group at position 3.
Synonyms:related_synonym: (3beta,5alpha)-cholestan-3-ol;   5alpha-cholestanol;   Formula=C27H48O;   InChI=1S/C27H48O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h18-25,28H,6-17H2,1-5H3/t19-,20+,21+,22+,23-,24+,25+,26+,27-/m1/s1;   InChIKey=QYIXCDOBOSTCEI-QCYZZNICSA-N;   SMILES=CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C;   cholestanol;   dihydrocholesterol;   zymostanol
 xref: CAS:80-97-7
 xref_mesh: MESH:D004083
 xref: Reaxys:2418594


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(5alpha)-cholestan-3beta-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases secretion ISO CYP27A1 protein results in increased secretion of Cholestanol CTD PMID:12117727 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 increases hydroxylation ISO CYP46A1 protein results in increased hydroxylation of Cholestanol CTD PMID:14640697 NCBI chr 6:127,247,543...127,274,765
Ensembl chr 6:127,243,315...127,274,760 		JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 multiple interactions ISO [Cholestanol co-treated with NAD] binds to HSD17B10 protein CTD PMID:25526675 NCBI chr  X:21,089,142...21,091,603
Ensembl chr  X:21,089,122...21,109,488 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases sulfation ISO SULT2A1 protein results in increased sulfation of Cholestanol CTD PMID:21839837 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    chemical entity 19836
      atom 19836
        nonmetal atom 19774
          carbon atom 19731
            organic molecular entity 19731
              lipid 17978
                steroid 14691
                  cholestanoid 362
                    (5alpha)-cholestan-3beta-ol 4
                      (24S)-hydroxycholestanol 0
                      (25R)-26-hydroxycholestanol 0
                      (5alpha,22S)-22-hydroxycholestan-3beta-ol 0
                      7-oxo-5alpha-cholestan-3beta-ol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    p-block element atom 19786
                      carbon group element atom 19734
                        carbon atom 19731
                          organic molecular entity 19731
                            organic molecule 19684
                              organic cyclic compound 19496
                                organic polycyclic compound 17245
                                  steroid 14691
                                    steroid fundamental parent 14488
                                      cholestane 368
                                        5alpha-cholestane 22
                                          (5alpha)-cholestan-3beta-ol 4
                                            (24S)-hydroxycholestanol 0
                                            (25R)-26-hydroxycholestanol 0
                                            (5alpha,22S)-22-hydroxycholestan-3beta-ol 0
                                            7-oxo-5alpha-cholestan-3beta-ol 0
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