.
1-(propan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)-2-propanol - Ontology Report - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:1-(propan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)-2-propanol
go back to main search page
Accession:CHEBI:91704 term browser browse the term
Definition:An aromatic ether that has formula C15H23NO3.
Synonyms:related_synonym: (+/-)-Oxprenolol;   Formula=C15H23NO3;   InChI=1S/C15H23NO3/c1-4-9-18-14-7-5-6-8-15(14)19-11-13(17)10-16-12(2)3/h4-8,12-13,16-17H,1,9-11H2,2-3H3;   InChIKey=CEMAWMOMDPGJMB-UHFFFAOYSA-N;   SMILES=CC(C)NCC(COC1=CC=CC=C1OCC=C)O;   dl-Oxprenolol;   oxprenolol HCl;   oxprenolol hydrochloride
 xref: CAS:6452-71-7;   Drug_Central:2027;   HMDB:HMDB0015520;   LINCS:LSM-1554
 xref_mesh: MESH:D010096

 Loading Annotations... 
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
X

show annotations for term's descendants           Sort by:
1-(propan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)-2-propanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 multiple interactions ISO Oxprenolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP] CTD PMID:15060759 NCBI chr 1:265,777,103...265,780,114
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions ISO [Oxprenolol binds to ADRB2 protein] which results in increased abundance of Cyclic AMP; [Oxprenolol binds to ADRB2 protein] which results in increased phosphorylation of MAPK1 protein; [Oxprenolol binds to ADRB2 protein] which results in increased phosphorylation of MAPK3 protein CTD PMID:17925438 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions ISO Oxprenolol binds to and results in increased activity of ADRB3 protein CTD PMID:1682311 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552 		JBrowse link
G Avp arginine vasopressin decreases expression ISO Oxprenolol results in decreased expression of AVP protein CTD PMID:6367368 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [Oxprenolol binds to ADRB2 protein] which results in increased phosphorylation of MAPK1 protein CTD PMID:17925438 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [Oxprenolol binds to ADRB2 protein] which results in increased phosphorylation of MAPK3 protein CTD PMID:17925438 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Ren renin multiple interactions
decreases activity 		ISO [Oxprenolol co-treated with Indomethacin] results in decreased activity of REN protein
Oxprenolol results in decreased activity of REN protein 		CTD PMID:6173514 PMID:6344036 PMID:7023672 PMID:7049707 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20845
    chemical entity 20843
      group 20786
        polyatomic entity 20786
          molecule 20657
            organic molecule 20637
              organic cyclic compound 20387
                organic aromatic compound 20222
                  aromatic ether 16781
                    1-(propan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)-2-propanol 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 20845
    subatomic particle 20843
      composite particle 20843
        hadron 20843
          baryon 20843
            nucleon 20843
              atomic nucleus 20843
                atom 20843
                  main group element atom 20766
                    main group molecular entity 20766
                      p-block molecular entity 20766
                        carbon group molecular entity 20699
                          organic molecular entity 20693
                            heteroorganic entity 20202
                              organochalcogen compound 19890
                                organooxygen compound 19792
                                  ether 17632
                                    aromatic ether 16781
                                      1-(propan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)-2-propanol 7
paths to the root