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hydroxyindoles - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:hydroxyindoles
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Accession:CHEBI:84729 term browser browse the term
Definition:Any member of the class of indoles carrying at least one hydroxy group.

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Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions 		EXP Serotonin results in increased expression of FOS mRNA; Serotonin results in increased expression of FOS protein
sarpogrelate inhibits the reaction [Serotonin results in increased expression of FOS mRNA]; sarpogrelate inhibits the reaction [Serotonin results in increased expression of FOS protein] 		CTD PMID:11426759 NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression 		EXP sarpogrelate inhibits the reaction [Serotonin results in increased expression of JUN mRNA]; sarpogrelate inhibits the reaction [Serotonin results in increased expression of JUN protein]
Serotonin results in increased expression of JUN mRNA; Serotonin results in increased expression of JUN protein 		CTD PMID:11426759 NCBI chr 6:153,686,425...153,687,635
Ensembl chr 6:153,685,682...153,687,636 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 increases phosphorylation
multiple interactions 		EXP Serotonin results in increased phosphorylation of MAPK1 protein
sarpogrelate inhibits the reaction [Serotonin results in increased phosphorylation of MAPK1 protein] 		CTD PMID:11426759 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation 		EXP sarpogrelate inhibits the reaction [Serotonin results in increased phosphorylation of MAPK3 protein] CTD PMID:11426759 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5181
    chemical entity 5180
      molecular entity 5179
        polyatomic entity 5160
          heteroatomic molecular entity 5131
            hydroxides 4962
              organic hydroxy compound 4894
                hydroxyindoles 4
                  (2E)-N-\{2-[5,5'-dihydroxy-3'-(2-\{[(2E)-1-hydroxy-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-ylidene]amino\}ethyl)-1H,1'H-[4,4'-biindole]-3-yl]ethyl\}-3-(4-hydroxy-3-methoxyphenyl)prop-2-enimidic acid 0
                  (2E)-N-\{2-[5,5'-dihydroxy-3'-(2-\{[(2E)-1-hydroxy-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-ylidene]amino\}ethyl)-1H,1'H-[4,4'-biindole]-3-yl]ethyl\}-3-(4-hydroxyphenyl)prop-2-enimidic acid 0
                  (2R,3R,4R,5S)-6-\{[7-carbamoyl-5-hydroxy-1-(4-phenylbutan-2-yl)indol-6-yl]oxy\}-3,4,5-trihydroxyoxane-2-carboxylic acid 0
                  (2R,3R,4R,5S)-6-\{[7-carbamoyl-6-hydroxy-1-(4-phenylbutan-2-yl)indol-5-yl]oxy\}-3,4,5-trihydroxyoxane-2-carboxylic acid 0
                  (4R)-2-[(5-hydroxy-1H-indol-3-yl)methyl]-4-thiazolidinecarboxylic acid 0
                  (5-hydroxyindol-3-yl)acetaldehyde 0
                  (E,E)-4,4''-Bi(N-4-hydroxycinnamoylserotonin) 0
                  2,2,2-trideuterio-N-[1,1,2,2-tetradeuterio-2-(5-hydroxy-1H-indol-3-yl)ethyl]acetamide 0
                  2-(8-methoxy-4-methyl-1-oxo-[1,2,4]triazino[4,5-a]indol-2-yl)-N-(3-propan-2-yloxypropyl)acetamide 0
                  2-Octadecyl-1H-indol-3-ol 0
                  2-hydroxy-(indol-3-yl)acetic acid 0
                  2-hydroxyindole 0
                  2-hydroxymelatonin 0
                  3-(1-methyl-4-piperidinyl)-1H-indol-5-ol 0
                  3-(5-hydroxyindol-3-yl)pyruvic acid 0
                  3-Formyl-6-hydroxyindole 0
                  3-hydroxy-3-methyloxindole 0
                  3-hydroxyindolin-2-one 0
                  4-Hydroxy-1H-indole-3-acetonitrile 0
                  4-hydroxy-indole-3-carbonyl nitrile 0
                  4-hydroxyindole 0
                  4-hydroxyindole-3-carbaldehyde 0
                  4-hydroxytryptamine 0
                  5,5',6,6'-tetrahydroxy-3,3'-biindolyl 0
                  5,6-dihydroxy-1-(4-phenylbutan-2-yl)indole-7-carboxamide 0
                  5-bromo-3-hydroxyindole 0
                  5-bromo-4-chloro-3-hydroxyindole 0
                  5-bromometagenediindole B 0
                  5-bromometagenediindole C 0
                  5-hydroxyindole 0
                  5-hydroxyindoleacetylglycine 0
                  6-Hydroxy-1H-indole-3-acetamide 0
                  6-hydroxy-N-acetyl-beta-oxotryptamine 0
                  AZD1080 0
                  Birnbaumin A 0
                  C.I. Pigment Blue 63 0
                  Hydroxysattazolin 0
                  Indigo dye 0
                  LSM-17205 0
                  LSM-19897 0
                  LSM-32074 0
                  Me-YTM-T 0
                  N-(1,3-benzodioxol-5-yl)-2-[(8-methoxy-5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio]acetamide 0
                  N-(2-hydroxy-5-methoxy-1H-indol-3-yl)acetamide 0
                  N-[(6-hydroxyindol-3-yl)acetyl]phenylalanine 0
                  N-acetylindoxyl 0
                  N-acylserotonin + 0
                  N-arachidonoyl-2-oxoserotonin 0
                  N-feruloylserotonin 0
                  N6-cis-p-Coumaroylserotonin 0
                  YTM-T 0
                  bromotopsentin 0
                  deoxyviolaceinic acid 0
                  dihydroxyindole + 0
                  dopaminechrome (enol form) 0
                  indoxyl + 0
                  notoamide S + 0
                  protoviolaceinic acid 0
                  proviolacein + 0
                  psilocin + 0
                  serotonin + 4
                  torkinib 0
                  violacein 0
                  violaceinic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 5181
    subatomic particle 5171
      composite particle 5171
        hadron 5171
          baryon 5171
            nucleon 5171
              atomic nucleus 5171
                atom 5171
                  main group element atom 5144
                    p-block element atom 5141
                      carbon group element atom 5059
                        carbon atom 5058
                          organic molecular entity 5058
                            organic molecule 5008
                              organic cyclic compound 4949
                                organic heterocyclic compound 4740
                                  organic heteropolycyclic compound 4533
                                    organic heterobicyclic compound 158
                                      benzopyrrole 73
                                        indoles 73
                                          hydroxyindoles 4
                                            (2E)-N-\{2-[5,5'-dihydroxy-3'-(2-\{[(2E)-1-hydroxy-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-ylidene]amino\}ethyl)-1H,1'H-[4,4'-biindole]-3-yl]ethyl\}-3-(4-hydroxy-3-methoxyphenyl)prop-2-enimidic acid 0
                                            (2E)-N-\{2-[5,5'-dihydroxy-3'-(2-\{[(2E)-1-hydroxy-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-ylidene]amino\}ethyl)-1H,1'H-[4,4'-biindole]-3-yl]ethyl\}-3-(4-hydroxyphenyl)prop-2-enimidic acid 0
                                            (2R,3R,4R,5S)-6-\{[7-carbamoyl-5-hydroxy-1-(4-phenylbutan-2-yl)indol-6-yl]oxy\}-3,4,5-trihydroxyoxane-2-carboxylic acid 0
                                            (2R,3R,4R,5S)-6-\{[7-carbamoyl-6-hydroxy-1-(4-phenylbutan-2-yl)indol-5-yl]oxy\}-3,4,5-trihydroxyoxane-2-carboxylic acid 0
                                            (4R)-2-[(5-hydroxy-1H-indol-3-yl)methyl]-4-thiazolidinecarboxylic acid 0
                                            (5-hydroxyindol-3-yl)acetaldehyde 0
                                            (E,E)-4,4''-Bi(N-4-hydroxycinnamoylserotonin) 0
                                            2,2,2-trideuterio-N-[1,1,2,2-tetradeuterio-2-(5-hydroxy-1H-indol-3-yl)ethyl]acetamide 0
                                            2-(8-methoxy-4-methyl-1-oxo-[1,2,4]triazino[4,5-a]indol-2-yl)-N-(3-propan-2-yloxypropyl)acetamide 0
                                            2-Octadecyl-1H-indol-3-ol 0
                                            2-hydroxy-(indol-3-yl)acetic acid 0
                                            2-hydroxyindole 0
                                            2-hydroxymelatonin 0
                                            3-(1-methyl-4-piperidinyl)-1H-indol-5-ol 0
                                            3-(5-hydroxyindol-3-yl)pyruvic acid 0
                                            3-Formyl-6-hydroxyindole 0
                                            3-hydroxy-3-methyloxindole 0
                                            3-hydroxyindolin-2-one 0
                                            4-Hydroxy-1H-indole-3-acetonitrile 0
                                            4-hydroxy-indole-3-carbonyl nitrile 0
                                            4-hydroxyindole 0
                                            4-hydroxyindole-3-carbaldehyde 0
                                            4-hydroxytryptamine 0
                                            5,5',6,6'-tetrahydroxy-3,3'-biindolyl 0
                                            5,6-dihydroxy-1-(4-phenylbutan-2-yl)indole-7-carboxamide 0
                                            5-bromo-3-hydroxyindole 0
                                            5-bromo-4-chloro-3-hydroxyindole 0
                                            5-bromometagenediindole B 0
                                            5-bromometagenediindole C 0
                                            5-hydroxyindole 0
                                            5-hydroxyindoleacetylglycine 0
                                            6-Hydroxy-1H-indole-3-acetamide 0
                                            6-hydroxy-N-acetyl-beta-oxotryptamine 0
                                            AZD1080 0
                                            Birnbaumin A 0
                                            C.I. Pigment Blue 63 0
                                            Hydroxysattazolin 0
                                            Indigo dye 0
                                            LSM-17205 0
                                            LSM-19897 0
                                            LSM-32074 0
                                            Me-YTM-T 0
                                            N-(1,3-benzodioxol-5-yl)-2-[(8-methoxy-5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio]acetamide 0
                                            N-(2-hydroxy-5-methoxy-1H-indol-3-yl)acetamide 0
                                            N-[(6-hydroxyindol-3-yl)acetyl]phenylalanine 0
                                            N-acetylindoxyl 0
                                            N-acylserotonin + 0
                                            N-arachidonoyl-2-oxoserotonin 0
                                            N-feruloylserotonin 0
                                            N6-cis-p-Coumaroylserotonin 0
                                            YTM-T 0
                                            bromotopsentin 0
                                            deoxyviolaceinic acid 0
                                            dihydroxyindole + 0
                                            dopaminechrome (enol form) 0
                                            indoxyl + 0
                                            notoamide S + 0
                                            protoviolaceinic acid 0
                                            proviolacein + 0
                                            psilocin + 0
                                            serotonin + 4
                                            torkinib 0
                                            violacein 0
                                            violaceinic acid 0
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