Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:violacein
go back to main search page
Accession:CHEBI:131914 term browser browse the term
Definition:A member of the class of hydroxyindoles resulting from the formal oxidative coupling between the 3-position of 1,3-dihydro-2H-indol-2-one and the 3-position of 1,3-dihydro-2H-pyrrol-2-one, which is substituted at the 5 position by a 5-hydroxy-1H-indol-3-yl group, where the newly-formed double bond has E configuration. It is a purple chromobacterial pigment that has antibacterial, antifungal, antiprotozoan, and anticancer properties.
Synonyms:exact_synonym: (3E)-3-[5-(5-hydroxy-1H-indol-3-yl)-2-oxo-1,2-dihydro-3H-pyrrol-3-ylidene]-1,3-dihydro-2H-indol-2-one
 related_synonym: Formula=C20H13N3O3;   InChI=1S/C20H13N3O3/c24-10-5-6-15-12(7-10)14(9-21-15)17-8-13(19(25)23-17)18-11-3-1-2-4-16(11)22-20(18)26/h1-9,21,24H,(H,22,26)(H,23,25)/b18-13+;   InChIKey=XAPNKXIRQFHCHN-QGOAFFKASA-N;   SMILES=O=C/1NC=2C(\\C1=C/3\\C=C(NC3=O)C=4C=5C(NC4)=CC=C(O)C5)=CC=CC2
 xref: CAS:548-54-9 "ChemIDplus";   KEGG:C21136
 xref_mesh: MESH:C063155
 xref: MetaCyc:VIOLACEIN;   PMID:21779844 "SUBMITTER";   PMID:25592762 "Europe PMC";   PMID:25652759 "Europe PMC";   PMID:26339614 "Europe PMC";   PMID:26428920 "Europe PMC";   PMID:26521020 "Europe PMC";   PMID:26916415 "Europe PMC";   Reaxys:49923 "Reaxys"


show annotations for term's descendants       view all columns           Sort by:
 
violacein term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp2 caspase 2 JBrowse link 4 71,652,358 71,670,228 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19657
    role 19601
      biological role 19599
        antimicrobial agent 17148
          antibacterial agent 12900
            violacein 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19657
    subatomic particle 19653
      composite particle 19653
        hadron 19653
          baryon 19653
            nucleon 19653
              atomic nucleus 19653
                atom 19653
                  main group element atom 19534
                    p-block element atom 19534
                      carbon group element atom 19417
                        carbon atom 19409
                          organic molecular entity 19409
                            organic group 18338
                              organic divalent group 18329
                                organodiyl group 18329
                                  carbonyl group 18218
                                    carbonyl compound 18218
                                      carboxylic acid 17918
                                        carboacyl group 16941
                                          univalent carboacyl group 16941
                                            carbamoyl group 16621
                                              carboxamide 16621
                                                lactam 2855
                                                  gamma-lactam 346
                                                    oxindoles 158
                                                      violacein 3
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.