CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: naphthodithiin
Accession: CHEBI:82826
browse the term
Definition: An organic heterotricyclic compound whose skeleton contains a naphthalene fused with a dithiin.
Synonyms: related_synonym: naphthodithiins
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Cat
catalase
increases expression
ISO
dithianone results in increased expression of CAT mRNA
CTD
PMID:35395341
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
G
Hmox1
heme oxygenase 1
increases expression
ISO
dithianone results in increased expression of HMOX1 mRNA
CTD
PMID:35395341
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Il1b
interleukin 1 beta
increases secretion
ISO
dithianone results in increased secretion of IL1B protein
CTD
PMID:35395341
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
ISO
dithianone results in increased expression of NQO1 mRNA
CTD
PMID:35395341
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557
G
Park7
Parkinsonism associated deglycase
multiple interactions
ISO
dithianone results in decreased activity of and results in increased oxidation of PARK7 protein
CTD
PMID:36842454
NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
G
Sod2
superoxide dismutase 2
increases expression
ISO
dithianone results in increased expression of SOD2 mRNA
CTD
PMID:35395341
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189
G
Tnf
tumor necrosis factor
increases secretion
ISO
dithianone results in increased secretion of TNF protein
CTD
PMID:35395341
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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