The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
CYP2B6 protein results in increased metabolism of notopterol [CYP2B6 protein results in increased metabolism of notopterol] promotes the reaction [Glutathione binds to notopterol]; notopterol inhibits the reaction [[CYP2B6 protein results in increased metabolism of Bupropion] which results in increased chemical synthesis of hydroxybupropion]; notopterol inhibits the reaction [CYP2B6 protein results in increased metabolism of Bupropion] notopterol results in decreased activity of CYP2B6 protein
notopterol results in decreased activity of CYP2D6 protein CYP2D6 protein results in increased metabolism of notopterol [CYP2D6 protein results in increased metabolism of notopterol] promotes the reaction [Glutathione binds to notopterol]; Antioxidants inhibits the reaction [notopterol results in decreased activity of CYP2D6 protein]; Glutathione inhibits the reaction [notopterol results in decreased activity of CYP2D6 protein]; NADP deficiency inhibits the reaction [notopterol results in decreased activity of CYP2D6 protein]; notopterol inhibits the reaction [[CYP2D6 protein results in increased metabolism of Dextromethorphan] which results in increased chemical synthesis of Dextrorphan]; notopterol inhibits the reaction [CYP2D6 protein results in increased metabolism of Dextromethorphan]; Quinidine inhibits the reaction [notopterol results in decreased activity of CYP2D6 protein]
CYP2E1 protein results in increased metabolism of notopterol notopterol results in decreased activity of CYP2E1 protein [CYP2E1 protein results in increased metabolism of notopterol] promotes the reaction [Glutathione binds to notopterol]; notopterol inhibits the reaction [[CYP2E1 protein results in increased metabolism of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol]; notopterol inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]
notopterol results in decreased activity of CYP3A4 protein [CYP3A4 protein results in increased metabolism of notopterol] promotes the reaction [Glutathione binds to notopterol]; notopterol inhibits the reaction [[CYP3A4 protein results in increased metabolism of Testosterone] which results in increased chemical synthesis of 6 beta-hydroxytestosterone]; notopterol inhibits the reaction [CYP3A4 protein results in increased metabolism of Testosterone]