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natamycin - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:natamycin
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Accession:CHEBI:7488 term browser browse the term
Definition:A macrolide antibiotic that has formula C33H47NO13, produced by several Streptomyces species including Streptomyces natalensis. It exhibits broad spectrum antifungal activity and used in eye drops, and as a food preservative, and also as a postharvest biofungicide for citrus and other fruit crops.
Synonyms:exact_synonym: (1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)-22-[(3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.0(5,7)]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
 related_synonym: CL 12,625;   CL 12625;   Delvocid;   Delvolan;   Delvopos;   E 235;   Formula=C33H47NO13;   InChI=1S/C33H47NO13/c1-18-10-8-6-4-3-5-7-9-11-21(45-32-30(39)28(34)29(38)19(2)44-32)15-25-27(31(40)41)22(36)17-33(42,47-25)16-20(35)14-24-23(46-24)12-13-26(37)43-18/h3-9,11-13,18-25,27-30,32,35-36,38-39,42H,10,14-17,34H2,1-2H3,(H,40,41)/b4-3+,7-5+,8-6+,11-9+,13-12+/t18-,19-,20+,21+,22+,23-,24-,25+,27-,28+,29-,30+,32?,33-/m1/s1;   InChIKey=NCXMLFZGDNKEPB-FFPOYIOWSA-N;   Mycophyt;   Myprozine;   Natacyn;   Natajen;   Natamatrix;   Natamax;   Pimaricin;   Pimarizin;   SMILES=[H][C@@]12C[C@H](O)C[C@]3(O)C[C@H](O)[C@@H](C(O)=O)[C@]([H])(C[C@@H](O[C@@H]4O[C@H](C)[C@@H](O)[C@H](N)[C@@H]4O)\\C=C\\C=C\\C=C\\C=C\\C[C@@H](C)OC(=O)\\C=C\\[C@H]1O2)O3;   Synogil;   antibiotic A-5283;   myuprozine;   natamicina;   natamycine;   natamycinum;   pimafucin;   pimaricine;   tennecetin
 xref: AGR:IND607246306;   AGR:IND607253996;   BPDB:2062;   CAS:7681-93-8;   Chemspider:10468784;   DrugBank:DB00826;   Drug_Central:1885;   FooDB:FDB002337;   HMDB:HMDB0014964;   KEGG:C08073;   KEGG:D00884
 xref_mesh: MESH:D010866
 xref: MetaCyc:CPD-17213;   PMID:18165687;   PMID:30562337;   PMID:31311527;   PMID:32382679;   PMID:32650062;   PMID:32891143;   PMID:33306429;   PMID:33320038;   PMID:33653522;   PMID:33737097;   PMID:33748084;   PMID:33822660;   PMID:33882328;   PMID:33973428;   PMID:34085850;   PMID:34311233;   PMID:34428517;   PMID:34515597;   PMID:34571612;   PMID:34574183;   Pesticides:natamycin;   Wikipedia:Natamycin

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natamycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clu clusterin increases expression ISO Natamycin results in increased expression of CLU mRNA CTD PMID:22863853 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cp ceruloplasmin increases expression ISO Natamycin results in increased expression of CP mRNA CTD PMID:22863853 NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Fga fibrinogen alpha chain increases expression ISO Natamycin results in increased expression of FGA mRNA CTD PMID:22863853 NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fgg fibrinogen gamma chain increases expression ISO Natamycin results in increased expression of FGG mRNA CTD PMID:22863853 NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:168,355,013...168,362,322 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression ISO Natamycin results in increased expression of HAVCR1 mRNA CTD PMID:22863853 NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,119,088...31,151,698 		JBrowse link
G Krt19 keratin 19 increases expression ISO Natamycin results in increased expression of KRT19 mRNA CTD PMID:22863853 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Lcn2 lipocalin 2 increases expression ISO Natamycin results in increased expression of LCN2 mRNA CTD PMID:22863853 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO Natamycin results in increased expression of SPP1 mRNA CTD PMID:22863853 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO Natamycin results in increased expression of TIMP1 mRNA CTD PMID:22863853 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20856
    role 20816
      biological role 20814
        antimicrobial agent 18575
          macrolide antibiotic 740
            natamycin 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 20856
    subatomic particle 20854
      composite particle 20854
        hadron 20854
          baryon 20854
            nucleon 20854
              atomic nucleus 20854
                atom 20854
                  main group element atom 20777
                    p-block element atom 20777
                      carbon group element atom 20710
                        carbon atom 20704
                          organic molecular entity 20704
                            heteroorganic entity 20215
                              organochalcogen compound 19902
                                organooxygen compound 19804
                                  ester 17797
                                    carboxylic ester 17253
                                      lactone 13369
                                        macrocyclic lactone 7622
                                          macrolide 7570
                                            macrolide antibiotic 740
                                              natamycin 9
paths to the root