CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: perflubron
Accession: CHEBI:38803
browse the term
Definition: A haloalkane that is perfluorooctane in which a fluorine attached to one of the terminal carbons has been replaced by a bromine.
Synonyms: exact_synonym: 1-bromo-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctane
related_synonym: 1-bromoheptadecafluorooctane; 1-bromoperfluorooctane; CF3-(CF2)6-CF2-Br; Formula=C8BrF17; Imagent GI; InChI=1S/C8BrF17/c9-7(22,23)5(18,19)3(14,15)1(10,11)2(12,13)4(16,17)6(20,21)8(24,25)26; InChIKey=WTWWXOGTJWMJHI-UHFFFAOYSA-N; LiquiVent; PFOB; SMILES=FC(C(C(C(C(C(C(C(Br)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F; bromure de n-perfluorooctyle; perfluoro-octylbromide; perfluorooctyl bromide
xref: Beilstein:2016022; CAS:423-55-2; Drug_Central:2102; Gmelin:613053
xref_mesh: MESH:C003072
xref: Patent:CA2156922; Patent:EP0549387; Patent:GB1381879; Patent:RU2162692; Patent:US3975512; Patent:US5928663; Patent:WO0234297; Patent:WO2006059063; Patent:WO2007105978; Patent:WO2007139827; Patent:WO9103267
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Cyp11a1
cytochrome P450, family 11, subfamily a, polypeptide 1
increases expression
ISO
perflubron results in increased expression of CYP11A1 mRNA
CTD
PMID:25871633
NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:58,404,669...58,434,338
G
Cyp11b2
cytochrome P450, family 11, subfamily b, polypeptide 2
increases expression
ISO
perflubron results in increased expression of CYP11B1 mRNA
CTD
PMID:25871633
NCBI chr 7:108,719,349...108,726,024
Ensembl chr 7:106,838,590...106,845,004
G
Cyp11b3
cytochrome P450, family 11, subfamily b, polypeptide 3
increases expression
ISO
perflubron results in increased expression of CYP11B2 mRNA
CTD
PMID:25871633
NCBI chr 7:108,689,319...108,694,808
Ensembl chr 7:106,808,559...106,814,048
G
Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
increases expression
ISO
perflubron results in increased expression of CYP17A1 mRNA
CTD
PMID:25871633
NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:245,535,462...245,541,573
G
Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
increases expression
ISO
perflubron results in increased expression of CYP19A1 mRNA
CTD
PMID:25871633
NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:54,553,165...54,580,758
G
Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
increases expression
ISO
perflubron results in increased expression of HMGCR mRNA
CTD
PMID:25871633
NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:27,997,525...28,019,703
G
Hsd17b1
hydroxysteroid (17-beta) dehydrogenase 1
increases expression
ISO
perflubron results in increased expression of HSD17B1 mRNA
CTD
PMID:25871633
NCBI chr10:86,510,011...86,512,211
Ensembl chr10:86,009,728...86,011,927
G
Hsd3b2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
increases expression
ISO
perflubron results in increased expression of HSD3B2 mRNA
CTD
PMID:25871633
NCBI chr 2:188,784,614...188,812,535
Ensembl chr 2:186,095,897...186,101,852
G
Star
steroidogenic acute regulatory protein
increases expression
ISO
perflubron results in increased expression of STAR mRNA
CTD
PMID:25871633
NCBI chr16:72,969,824...72,974,447
Ensembl chr16:66,264,807...66,271,672
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all