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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Nilvadipine
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Accession:CHEBI:31911 term browser browse the term
Synonyms:related_synonym: FR-34235;   Formula=C19H19N3O6;   InChI=1S/C19H19N3O6/c1-10(2)28-19(24)15-11(3)21-14(9-20)17(18(23)27-4)16(15)12-6-5-7-13(8-12)22(25)26/h5-8,10,16,21H,1-4H3;   InChIKey=FAIIFDPAEUKBEP-UHFFFAOYSA-N;   SMILES=CC1=C(C(C(=C(N1)C#N)C(=O)OC)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC(C)C;   nivadil;   nivaldipine
 alt_id: CHEBI:95208
 xref: CAS:75530-68-6;   Drug_Central:1934;   HMDB:HMDB0015657;   KEGG:D01908;   LINCS:LSM-6501
 xref_mesh: MESH:C035100


show annotations for term's descendants           Sort by:
Nilvadipine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO nilvadipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin] CTD PMID:11895100 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 decreases activity ISO nilvadipine results in decreased activity of CYP2J2 protein CTD PMID:30965050 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 multiple interactions EXP nilvadipine inhibits the reaction [Cyclosporine results in increased expression of FLT1 mRNA] CTD PMID:12110003 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Nefl neurofilament light chain multiple interactions EXP nilvadipine inhibits the reaction [Rotenone results in decreased expression of NEFL mRNA] CTD PMID:31969611 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793 		JBrowse link
G Ren renin multiple interactions EXP nilvadipine inhibits the reaction [Tacrolimus results in increased expression of REN protein] CTD PMID:7533848 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    chemical entity 19839
      group 19798
        pseudohalo group 4573
          cyano group 4573
            nitrile 4573
              Nilvadipine 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      carbon group element atom 19737
                        carbon atom 19733
                          organic molecular entity 19733
                            heteroorganic entity 19492
                              organochalcogen compound 19255
                                organooxygen compound 19172
                                  carbon oxoacid 18641
                                    carboxylic acid 18638
                                      monocarboxylic acid 18008
                                        fatty acid 16809
                                          fatty acid derivative 8969
                                            fatty alcohol 6108
                                              secondary fatty alcohol 788
                                                propan-2-ol 788
                                                  isopropyl ester 773
                                                    Nilvadipine 5
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