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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:gibberellin A3
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Accession:CHEBI:28833 term browser browse the term
Definition:A C19-gibberellin that is a pentacyclic diterpenoid responsible for promoting growth and elongation of cells in plants. Initially identified in Gibberella fujikuroi,it differs from gibberellin A1 in the presence of a double bond between C-3 and C-4.
Synonyms:exact_synonym: (1R,2R,5S,8S,9S,10R,11S,12S)-5,12-dihydroxy-11-methyl-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.1(5,8).0(1,10).0(2,8)]heptadec-13-ene-9-carboxylic acid;   2beta,7alpha-dihydroxy-1beta-methyl-8-methylidene-13-oxo-4a,1alpha-epoxymethano-4aalpha,4bbeta-gibb-3-ene-10beta-carboxylic acid
 related_synonym: Formula=C19H22O6;   GA3;   Gibberellic acid;   Gibberellin;   Gibberellinsaeure;   InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10-,11+,12-,13-,16-,17+,18+,19-/m1/s1;   InChIKey=IXORZMNAPKEEDV-OBDJNFEBSA-N;   SMILES=[H][C@@]12CC[C@]3(O)C[C@]1(CC3=C)[C@@H](C(O)=O)[C@]1([H])[C@@]3(C)[C@@H](O)C=C[C@@]21OC3=O;   gibberellic acid GA3;   gibberellin 3
 alt_id: CHEBI:24243;   CHEBI:5340
 xref: AGR:IND44675921;   BPDB:371;   Beilstein:54346;   CAS:77-06-5;   DrugBank:DB07814;   HMDB:HMDB0003559;   KEGG:C01699;   KNApSAcK:C00000003;   LIPID_MAPS_instance:LMPR0104170002
 xref_mesh: MESH:C007842
 xref: MetaCyc:GIBBERELLIN;   PDBeChem:GA3;   PMID:18948165;   PMID:19815399;   PMID:21216576;   PMID:22044348;   PMID:22516192;   PMID:23076568;   PMID:23818834;   PMID:23857350;   PMID:24232845;   Reaxys:54346;   Wikipedia:Gibberellic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:58590


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gibberellin A3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions
increases expression		 EXP Decitabine promotes the reaction [gibberellic acid results in increased expression of CASP3 mRNA]; gibberellic acid promotes the reaction [Decitabine results in increased expression of CASP3 mRNA]
gibberellic acid results in increased expression of CASP3 mRNA; gibberellic acid results in increased expression of CASP3 protein		 CTD PMID:31733319 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 decreases methylation
increases expression		 EXP gibberellic acid results in decreased methylation of CASP8 gene; gibberellic acid results in decreased methylation of CASP8 promoter
gibberellic acid results in increased expression of CASP8 mRNA; gibberellic acid results in increased expression of CASP8 protein		 CTD PMID:31733319 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases expression EXP gibberellic acid results in increased expression of CASP9 mRNA; gibberellic acid results in increased expression of CASP9 protein CTD PMID:31733319 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression EXP gibberellic acid results in decreased expression of DNMT3A mRNA CTD PMID:31733319 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression EXP gibberellic acid results in decreased expression of DNMT3B mRNA CTD PMID:31733319 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Fas Fas cell surface death receptor increases expression EXP gibberellic acid results in increased expression of FAS mRNA; gibberellic acid results in increased expression of FAS protein CTD PMID:31733319 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      biological role 19782
        biochemical role 19496
          metabolite 19484
            eukaryotic metabolite 19307
              plant metabolite 17943
                gibberellin A3 6
                  gibberellin A3 O-beta-D-glucoside 0
                  gibberellin A3 methyl ester 0
                  gibberellin A3 norketone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    main group molecular entity 19756
                      s-block molecular entity 19595
                        hydrogen molecular entity 19582
                          hydrides 19095
                            organic hydride 18669
                              organic fundamental parent 18669
                                hydrocarbon 18415
                                  terpene 14057
                                    terpenoid 13755
                                      diterpenoid 13024
                                        gibberellin 6
                                          C19-gibberellin 6
                                            gibberellin A3 6
                                              gibberellin A3 O-beta-D-glucoside 0
                                              gibberellin A3 methyl ester 0
                                              gibberellin A3 norketone 0
paths to the root