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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:EC 4.2.1.1 (carbonic anhydrase) inhibitor
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Accession:CHEBI:23018 term browser browse the term
Definition:An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of carbonic anhydrase (EC 4.2.1.1). Such compounds reduce the secretion of H(+) ions by the proximal kidney tubule.
Synonyms:related_synonym: EC 4.2.1.1 (carbonic anhydrase) inhibitors;   EC 4.2.1.1 inhibitor;   EC 4.2.1.1 inhibitors;   anhydrase inhibitor;   anhydrase inhibitors;   carbonate anhydrase inhibitor;   carbonate anhydrase inhibitors;   carbonate dehydratase inhibitor;   carbonate dehydratase inhibitors;   carbonate hydro-lyase (carbon-dioxide-forming) inhibitor;   carbonate hydro-lyase (carbon-dioxide-forming) inhibitors;   carbonate hydro-lyase inhibitor;   carbonate hydro-lyase inhibitors;   carbonic acid anhydrase inhibitor;   carbonic acid anhydrase inhibitors;   carbonic anhydrase A inhibitor;   carbonic anhydrase A inhibitors;   carbonic anhydrase inhibitor;   carbonic anhydrase inhibitors;   carboxyanhydrase inhibitor;   carboxyanhydrase inhibitors
 xref: Wikipedia:Carbonic_anhydrase_inhibitor


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      CHEBI ontology 26503
        role 26325
          biological role 26304
            biochemical role 25517
              enzyme inhibitor 22390
                EC 4.* (lyase) inhibitor 8212
                  EC 4.2.* (C-O lyase) inhibitor 5158
                    EC 4.2.1.* (hydro-lyases) inhibitor 5158
                      EC 4.2.1.1 (carbonic anhydrase) inhibitor 2966
                        N-benzyl-4-sulfamoylbenzamide 0
                        SLC-0111 3
                        acetazolamide + 64
                        astragaloside IV 50
                        brinzolamide + 5
                        diclofenamide 3
                        dorzolamide + 2
                        dorzolamide hydrochloride 2
                        ethoxzolamide 3
                        indisulam 0
                        latanoprost 1
                        latanoprost free acid + 1
                        sulfanilamide + 2898
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