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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:indisulam
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Accession:CHEBI:145431 term browser browse the term
Definition:A chloroindole that is 3-chloro-1H-indole substituted by a [(4-sulfamoylphenyl)sulfonyl]nitrilo group at position 7. It is a carbonic anhydrase inhibitor and a potential anti-cancer agent currently in clinical development.
Synonyms:exact_synonym: N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide
 related_synonym: E-7070;   E7070;   Formula=C14H12ClN3O4S2;   InChI=1S/C14H12ClN3O4S2/c15-12-8-17-14-11(12)2-1-3-13(14)18-24(21,22)10-6-4-9(5-7-10)23(16,19)20/h1-8,17-18H,(H2,16,19,20);   InChIKey=SETFNECMODOHTO-UHFFFAOYSA-N;   N(1)-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide;   N-(3-chloro-1H-indol-7-yl)-4-sulfamoylbenzenesulfonamide;   SMILES=C=1C=CC(=C2NC=C(C12)Cl)NS(C3=CC=C(C=C3)S(N)(=O)=O)(=O)=O;   indisulamum
 xref: CAS:165668-41-7;   DrugBank:DB06370;   KEGG:D04522;   PDBeChem:EF6;   PMID:11677118;   PMID:12351604;   PMID:12439332;   PMID:12445024;   PMID:12556221;   PMID:14684331;   PMID:17285128;   PMID:18637887;   PMID:22349812;   PMID:28302793;   PMID:29660836


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  CHEBI ontology 19932
    role 19904
      application 19741
        pharmaceutical 19579
          drug 19579
            antineoplastic agent 17820
              indisulam 0
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Term Annotations click to browse term
  CHEBI ontology 19932
    subatomic particle 19930
      composite particle 19930
        hadron 19930
          baryon 19930
            nucleon 19930
              atomic nucleus 19930
                atom 19930
                  main group element atom 19876
                    p-block element atom 19876
                      carbon group element atom 19816
                        carbon atom 19812
                          organic molecular entity 19812
                            organic molecule 19764
                              organic cyclic compound 19553
                                organic heterocyclic compound 18905
                                  organic heteropolycyclic compound 18317
                                    organic heterobicyclic compound 17256
                                      benzopyrrole 9736
                                        indoles 9424
                                          haloindole 4
                                            chloroindole 0
                                              indisulam 0
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