Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


go back to main search page
Accession:CHEBI:101085 term browser browse the term
Definition:A sulfonamide that is benzene-1,3-disulfonamide in which the hydrogens at positions 4 and 5 are substituted by chlorine. An oral carbonic anhydrase inhibitor, it partially suppresses the secretion (inflow) of aqueous humor in the eye and so reduces intraocular pressure. It is used for the treatment of glaucoma.
Synonyms:related_synonym: 1,3-disulfamoyl-4,5-dichlorobenzene;   1,3-disulfamyl-4,5-dichlorobenzene;   3,4-dichloro-5-sulfamylbenzenesulfonamide;   4,5-DICHLOROBENZENE-1,3-DISULFONAMIDE;   4,5-dichloro-1,3-benzenedisulfonamide;   4,5-dichloro-1,3-disulfamoylbenzene;   4,5-dichloro-benzene-1,3-disulfonic acid diamide;   4,5-dichloro-m-benzenedisulfonamide;   DICHLORPHENAMIDE;   Dichlorophenamide;   Formula=C6H6Cl2N2O4S2;   InChI=1S/C6H6Cl2N2O4S2/c7-4-1-3(15(9,11)12)2-5(6(4)8)16(10,13)14/h1-2H,(H2,9,11,12)(H2,10,13,14);   InChIKey=GJQPMPFPNINLKP-UHFFFAOYSA-N;   SMILES=NS(=O)(=O)c1cc(Cl)c(Cl)c(c1)S(N)(=O)=O;   dichlofenamide;   diclofenamida;   diclofenamidum
 alt_id: CHEBI:4505;   CHEBI:47477
 xref: Beilstein:2703329 "Beilstein";   CAS:120-97-8 "ChemIDplus";   CAS:120-97-8 "KEGG COMPOUND";   CAS:120-97-8 "NIST Chemistry WebBook";   DrugBank:DB01144;   Drug_Central:864 "DrugCentral";   KEGG:C07459;   KEGG:D00518;   LINCS:LSM-3602
 xref_mesh: MESH:D004005
 xref: PDBeChem:I7A;   Patent:US2835702;   Wikipedia:Dichlorphenamide

show annotations for term's descendants       view all columns           Sort by:
diclofenamide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ca3 carbonic anhydrase 3 JBrowse link 2 88,126,519 88,136,063 RGD:6480464
G Car2 carbonic anhydrase 2 JBrowse link 2 88,097,740 88,112,868 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      application 19220
        pharmaceutical 19081
          drug 19081
            ophthalmology drug 391
              diclofenamide 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic molecule 19327
                              organic cyclic compound 19076
                                carbocyclic compound 17501
                                  benzenoid aromatic compound 17022
                                    benzenes 16737
                                      chlorobenzenes 12573
                                        dichlorobenzene 9677
                                          diclofenamide 2
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.