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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Vitisin A
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Accession:CHEBI:189580 term browser browse the term
Synonyms:exact_synonym: (1S,8S,9R,16S)-9-[5-[(E)-2-[(2S,3S)-3-(3,5-dihydroxyphenyl)-6-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzouran-4-yl]ethenyl]-2-hydroxyphenyl]-8,16-bis(4-hydroxyphenyl)-15-oxatetracyclo[8.6.1.02,7.014,17]heptadeca-2(7),3,5,10(17),11,13-hexaene-4,6,12-triol
 related_synonym: Formula=C56H42O12;   InChI=1S/C56H42O12/c57-33-10-4-28(5-11-33)49-51(42-23-40(64)26-47-53(42)54(43-22-39(63)24-45(66)52(43)49)56(68-47)30-8-14-35(59)15-9-30)41-17-27(2-16-44(41)65)1-3-31-18-38(62)25-46-48(31)50(32-19-36(60)21-37(61)20-32)55(67-46)29-6-12-34(58)13-7-29/h1-26,49-51,54-66H/b3-1+/t49-,50+,51+,54+,55-,56-/m1/s1;   InChIKey=XAXVWWYPKOGXSY-DBHYGPPCSA-N;   SMILES=O1[C@@H]([C@@]2(C3=C([C@@]([C@H](C4=C2C=C(O)C=C4O)C5=CC=C(O)C=C5)(C=6C=C(C=CC6O)/C=C/C7=C8[C@@H]([C@H](OC8=CC(O)=C7)C9=CC=C(O)C=C9)C%10=CC(O)=CC(O)=C%10)[H])C=C(O)C=C13)[H])C%11=CC=C(O)C=C%11
 xref: CAS:142449-89-6;   Chemspider:17288137
 xref_mesh: MESH:C412469


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Vitisin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP
ISO		 vitisin A inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK1 protein]
vitisin A inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK1 protein modified form]		 CTD PMID:19135555 PMID:21871475 NCBI chr11:97,462,025...97,529,193 JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP
ISO		 vitisin A inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK3 protein]
vitisin A inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK3 protein modified form]		 CTD PMID:19135555 PMID:21871475 NCBI chr 1:190,797,189...190,803,411 JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO vitisin A inhibits the reaction [Lipopolysaccharides results in increased degradation of and results in increased phosphorylation of NFKBIA protein] CTD PMID:19135555 NCBI chr 6:78,593,844...78,597,307 JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO vitisin A inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:19135555 NCBI chr10:64,313,335...64,349,221 JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions EXP vitisin A inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK1 protein]; vitisin A inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK3 protein]; vitisin A inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PDGFRB protein]; vitisin A inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PLCG1 protein] CTD PMID:21871475 NCBI chr 7:113,419,882...113,438,343 JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions EXP vitisin A inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PDGFRB protein] CTD PMID:21871475 NCBI chr18:56,770,348...56,809,228 JBrowse link
G Plcg1 phospholipase C, gamma 1 multiple interactions EXP vitisin A inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PLCG1 protein] CTD PMID:21871475 NCBI chr 3:149,385,587...149,416,330 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19899
    chemical entity 19897
      atom 19897
        nonmetal atom 19820
          oxygen atom 19560
            oxygen molecular entity 19560
              organooxygen compound 19215
                oxacycle 17926
                  benzofurans 3334
                    Vitisin A 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19899
    subatomic particle 19897
      composite particle 19897
        hadron 19897
          baryon 19897
            nucleon 19897
              atomic nucleus 19897
                atom 19897
                  main group element atom 19836
                    main group molecular entity 19836
                      p-block molecular entity 19836
                        carbon group molecular entity 19776
                          organic molecular entity 19772
                            organic molecule 19725
                              organic cyclic compound 19517
                                organic heterocyclic compound 18894
                                  organic heteropolycyclic compound 18322
                                    benzofurans 3334
                                      Vitisin A 7
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