Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dinitrogen oxide
go back to main search page
Accession:CHEBI:17045 term browser browse the term
Definition:A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.
Synonyms:exact_synonym: oxidodinitrogen(N--N)
 related_synonym: Dinitrogen monoxide;   Distickstoffmonoxid;   E942;   Formula=N2O;   InChI=1S/N2O/c1-2-3;   InChIKey=GQPLMRYTRLFLPF-UHFFFAOYSA-N;   Lachgas;   N2O;   NNO;   R-744A;   SMILES=[O-][N+]#N;   Stickstoff(I)-oxid;   diazyne 1-oxide;   factitious air;   gaz hilarant;   laughing gas;   nitrogen protoxide;   nitrogenium oxydulatum;   nitrous oxide;   oxyde nitreux;   protoxyde d'azote
 alt_id: CHEBI:14661;   CHEBI:25568;   CHEBI:44250;   CHEBI:7598
 xref: CAS:10024-97-2;   Drug_Central:4238;   Gmelin:2153410;   KEGG:C00887;   KEGG:D00102
 xref_mesh: MESH:D009609
 xref: PDBeChem:N2O;   PMID:11159233;   PMID:11811748;   PMID:15316643;   PMID:15644008;   PMID:16179535;   PMID:17093360;   PMID:18992971;   PMID:19910265;   PMID:21622873;   PMID:23643142;   PMID:7880215;   Reaxys:8137358;   UM-BBD_compID:c0650;   Wikipedia:Nitrous_oxide


show annotations for term's descendants           Sort by:
dinitrogen oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cntf ciliary neurotrophic factor multiple interactions
decreases activity		 ISO Nitrous Oxide inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT1 protein]; Nitrous Oxide inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein]
Nitrous Oxide results in decreased activity of CNTF protein
Nitrous Oxide inhibits the reaction [CNTF protein results in increased activity of STAT3 protein]		 CTD PMID:15748169 NCBI chr 1:209,887,854...209,889,877
Ensembl chr 1:209,887,854...209,889,877 		JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 multiple interactions ISO [Isoflurane co-treated with Nitrous Oxide] affects the expression of GABRA4 mRNA CTD PMID:16733821 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A multiple interactions ISO GRIN2A protein affects the susceptibility to [Nitrous Oxide co-treated with sevoflurane] CTD PMID:15731593 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase decreases activity ISO Nitrous Oxide results in decreased activity of MTR protein CTD PMID:18472229 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822 		JBrowse link
G Pla2g7 phospholipase A2 group VII affects expression ISO Nitrous Oxide affects the expression of PLA2G7 CTD PMID:21356620 NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476 		JBrowse link
G Pomc proopiomelanocortin increases secretion EXP Nitrous Oxide results in increased secretion of POMC protein CTD PMID:2846107 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO Nitrous Oxide inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT1 protein] CTD PMID:15748169 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO Nitrous Oxide inhibits the reaction [CNTF protein results in increased activity of STAT3 protein]
Nitrous Oxide inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein]		 CTD PMID:15748169 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    role 19839
      application 19703
        refrigerant 18295
          dinitrogen oxide 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19890
    subatomic particle 19867
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19867
              atomic nucleus 19888
                atom 19888
                  main group element atom 19806
                    p-block element atom 19806
                      chalcogen 19577
                        oxygen atom 19549
                          oxygen molecular entity 19529
                            oxide 12867
                              inorganic oxide 7797
                                nitrogen oxide 426
                                  dinitrogen oxide 8
paths to the root