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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:phytanic acid
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Accession:CHEBI:16285 term browser browse the term
Definition:A branched-chain saturated fatty acid consisting of hexadecanoic acid carrying methyl substituents at positions 3, 7, 11 and 15.
Synonyms:exact_synonym: 3,7,11,15-tetramethylhexadecanoic acid
 related_synonym: 3,7,11,15-Tetramethyl-hexadecansaeure;   3,7,11,15-tetramethyl-hexadecanoic acid;   Formula=C20H40O2;   InChI=1S/C20H40O2/c1-16(2)9-6-10-17(3)11-7-12-18(4)13-8-14-19(5)15-20(21)22/h16-19H,6-15H2,1-5H3,(H,21,22);   InChIKey=RLCKHJSFHOZMDR-UHFFFAOYSA-N;   SMILES=CC(C)CCCC(C)CCCC(C)CCCC(C)CC(O)=O
 alt_id: CHEBI:26111;   CHEBI:8189
 xref: CAS:14721-66-5;   KEGG:C01607;   LIPID_MAPS_instance:LMFA01020251
 xref_mesh: MESH:D010831
 xref: PMID:12187408;   PMID:17956237;   PMID:9819701;   Reaxys:1789963
 cyclic_relationship: is_conjugate_acid_of CHEBI:37257


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phytanic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fabp1 fatty acid binding protein 1 affects binding
increases expression
multiple interactions		 ISO Phytanic Acid binds to FABP1 protein
Phytanic Acid results in increased expression of FABP1 mRNA; Phytanic Acid results in increased expression of FABP1 protein
PPARA protein affects the reaction [Phytanic Acid results in increased expression of FABP1 mRNA]		 CTD PMID:10191295 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
affects binding		 ISO PPARA protein affects the reaction [Phytanic Acid results in increased expression of FABP1 mRNA]
Phytanic Acid binds to PPARA protein		 CTD PMID:10191295 PMID:23843199 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta affects binding ISO Phytanic Acid binds to PPARB protein CTD PMID:23843199 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding ISO Phytanic Acid binds to PPARG protein CTD PMID:23843199 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Rxrb retinoid X receptor beta affects binding ISO Phytanic Acid binds to RXRB protein CTD PMID:11939783 NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773 		JBrowse link
G Scp2 sterol carrier protein 2 affects degradation ISO SCP2 protein affects the degradation of Phytanic Acid CTD PMID:10191295 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287 		JBrowse link
2-hydroxyphytanic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rxra retinoid X receptor alpha affects binding ISO 2-hydroxyphytanic acid binds to RXRA protein CTD PMID:23843199 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Rxrb retinoid X receptor beta affects binding ISO 2-hydroxyphytanic acid binds to RXRB protein CTD PMID:23843199 NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773 		JBrowse link
G Rxrg retinoid X receptor gamma affects binding ISO 2-hydroxyphytanic acid binds to RXRG protein CTD PMID:23843199 NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19898
    role 19868
      biological role 19866
        biochemical role 19571
          metabolite 19558
            eukaryotic metabolite 19383
              plant metabolite 17996
                hexadecanoic acid 2502
                  phytanic acid 8
                    2-hydroxyphytanic acid + 3
                    2-oxophytanic acid 0
                    omega-hydroxyphytanic acid 0
                    phytanoyl-CoA + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19898
    subatomic particle 19896
      composite particle 19896
        hadron 19896
          baryon 19896
            nucleon 19896
              atomic nucleus 19896
                atom 19896
                  main group element atom 19835
                    p-block element atom 19835
                      carbon group element atom 19774
                        carbon atom 19771
                          organic molecular entity 19771
                            heteroorganic entity 19528
                              organochalcogen compound 19290
                                organooxygen compound 19206
                                  carbon oxoacid 18675
                                    carboxylic acid 18672
                                      monocarboxylic acid 18017
                                        fatty acid 16843
                                          saturated fatty acid 16565
                                            straight-chain saturated fatty acid 16100
                                              hexadecanoic acid 2502
                                                phytanic acid 8
                                                  2-hydroxyphytanic acid + 3
                                                  2-oxophytanic acid 0
                                                  omega-hydroxyphytanic acid 0
                                                  phytanoyl-CoA + 0
paths to the root