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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:hexadecanoic acid
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Accession:CHEBI:15756 term browser browse the term
Definition:A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
Synonyms:related_synonym: 1-Pentadecanecarboxylic acid;   1-hexyldecanoic acid;   16:00;   C16;   C16 fatty acid;   C16:0;   CH3-[CH2]14-COOH;   FA 16:0;   Formula=C16H32O2;   Hexadecanoate;   Hexadecylic acid;   Hexaectylic acid;   InChI=1S/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H,17,18);   InChIKey=IPCSVZSSVZVIGE-UHFFFAOYSA-N;   Palmitate;   Palmitic acid;   Palmitinic acid;   Palmitinsaeure;   Pentadecanecarboxylic acid;   SMILES=CCCCCCCCCCCCCCCC(O)=O;   cetylic acid;   hexadecoic acid;   n-hexadecanoic acid;   n-hexadecoic acid
 alt_id: CHEBI:14730;   CHEBI:233028;   CHEBI:24540;   CHEBI:24541;   CHEBI:24542;   CHEBI:24550;   CHEBI:29889;   CHEBI:35978;   CHEBI:44952
 xref: Beilstein:607489;   CAS:57-10-3;   DrugBank:DB03796;   Gmelin:190200;   HMDB:HMDB0000220;   KEGG:C00249;   KEGG:D05341;   KNApSAcK:C00001233;   KNApSAcK:C00030479;   LIPID_MAPS_instance:LMFA01010001
 xref_mesh: MESH:D019308
 xref: MetaCyc:PALMITATE;   PDBeChem:PLM;   PMID:12492626;   PMID:15357969;   PMID:1589452;   PMID:16509590;   PMID:16884313;   PMID:17439666;   PMID:17502136;   PMID:20001317;   PMID:22735334;   PMID:25584012;   PMID:28600633;   PPDB:1336;   Reaxys:607489;   Wikipedia:Palmitic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:7896


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hexadecanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ABCA1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ABCA1 mRNA CTD PMID:30547786 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abca2 ATP binding cassette subfamily A member 2 affects expression ISO Palmitic Acid affects the expression of ABCA2 mRNA CTD PMID:33736254 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO [Palmitic Acid co-treated with Arsenic] affects the expression of ABCC1 mRNA CTD PMID:33736254 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [Palmitic Acid co-treated with Arsenic] results in increased expression of ABCC2 mRNA CTD PMID:33736254 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of ABCC5 protein CTD PMID:28073184 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
JBrowse link
G Abce1 ATP binding cassette subfamily E member 1 increases expression ISO Palmitic Acid results in increased expression of ABCE1 protein CTD PMID:24651439 NCBI chr19:28,205,566...28,230,489
Ensembl chr19:28,205,555...28,230,489
JBrowse link
G Abcf1 ATP binding cassette subfamily F member 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of ABCF1 protein CTD PMID:28073184 NCBI chr20:2,802,519...2,815,433
Ensembl chr20:2,802,488...2,815,433
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 increases expression ISO Palmitic Acid results in increased expression of ABCG1 mRNA CTD PMID:16730733 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Acaca acetyl-CoA carboxylase alpha decreases phosphorylation
increases expression
multiple interactions
ISO Palmitic Acid results in decreased phosphorylation of ACACA protein
Palmitic Acid results in increased expression of ACACA mRNA
amlexanox inhibits the reaction [Palmitic Acid results in increased expression of ACACA mRNA]
[Fructose co-treated with Palmitic Acid] results in decreased expression of ACACA protein modified form; [Fructose co-treated with Palmitic Acid] results in increased expression of ACACA protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of ACACA protein modified form]; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of ACACA protein]; Ivermectin inhibits the reaction [Palmitic Acid results in decreased phosphorylation of ACACA protein]
CTD PMID:30738135 PMID:32730863 PMID:32905826 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain multiple interactions EXP [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA] CTD PMID:26190035 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Acadsb acyl-CoA dehydrogenase, short/branched chain multiple interactions ISO 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA]; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA] CTD PMID:32613381 NCBI chr 1:186,188,939...186,227,796
Ensembl chr 1:186,188,987...186,230,379
JBrowse link
G Acin1 apoptotic chromatin condensation inducer 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of ACIN1 protein CTD PMID:28073184 NCBI chr15:28,102,112...28,147,001
Ensembl chr15:28,102,112...28,147,001
JBrowse link
G Ackr3 atypical chemokine receptor 3 multiple interactions ISO [Palmitic Acid co-treated with Arsenic] affects the expression of ACKR3 mRNA CTD PMID:33736254 NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237
JBrowse link
G Acly ATP citrate lyase multiple interactions
increases expression
ISO acanthoic acid inhibits the reaction [Palmitic Acid results in increased expression of ACLY mRNA]; GW 3965 inhibits the reaction [Palmitic Acid results in increased expression of ACLY mRNA]; pregna-4,17-diene-3,16-dione inhibits the reaction [Palmitic Acid results in increased expression of ACLY mRNA] CTD PMID:31421115 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ACSL1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ACSL1 mRNA CTD PMID:30547786 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ACSL4 mRNA CTD PMID:30547786 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 multiple interactions
increases expression
affects response to substance
ISO [ACSL5 protein affects the susceptibility to Palmitic Acid] which affects the abundance of Adenosine Triphosphate
Palmitic Acid results in increased expression of ACSL5 mRNA
CTD PMID:32347412 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO [Oleic Acid co-treated with Palmitic Acid] results in increased expression of ACTA2 mRNA CTD PMID:26187275 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Add1 adducin 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of ADD1 protein CTD PMID:28073184 NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182
JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 increases expression
multiple interactions
ISO Palmitic Acid results in increased expression of ADGRE1 mRNA
amlexanox inhibits the reaction [Palmitic Acid results in increased expression of ADGRE1 mRNA]
CTD PMID:32905826 NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression
multiple interactions
EXP
ISO
Palmitic Acid results in decreased expression of ADIPOQ mRNA
3-(4-chlorophenyl)-N-methyl-N'-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboxamidine analog inhibits the reaction [[osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOQ mRNA]; 3-(4-chlorophenyl)-N-methyl-N'-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboxamidine analog inhibits the reaction [[osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOQ protein]; [osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOQ mRNA; [osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOQ protein
AICA ribonucleotide inhibits the reaction [Palmitic Acid results in decreased expression of ADIPOQ mRNA]; Metformin inhibits the reaction [Palmitic Acid results in decreased expression of ADIPOQ mRNA]; Resveratrol inhibits the reaction [Palmitic Acid results in decreased expression of ADIPOQ mRNA]; Salicylic Acid inhibits the reaction [Palmitic Acid results in decreased expression of ADIPOQ mRNA]
CTD PMID:25108154 PMID:31454063 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adipor1 adiponectin receptor 1 multiple interactions ISO 3-(4-chlorophenyl)-N-methyl-N'-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboxamidine analog inhibits the reaction [[osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOR1 protein]; [osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOR1 protein CTD PMID:31454063 NCBI chr13:45,859,461...45,879,248
Ensembl chr13:45,859,533...45,879,241
JBrowse link
G Adipor2 adiponectin receptor 2 decreases expression
multiple interactions
increases expression
ISO
EXP
palmitic acid decreases expression of ADIPOR2 mRNA and protein in hepatocellular carcinoma cells
3-(4-chlorophenyl)-N-methyl-N'-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboxamidine analog inhibits the reaction [[osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOR2 protein]; [osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOR2 protein
palmitic acid cotreated with ethanol increases expression of adipor2 mRNA in rat primary hepatocytes
CTD PMID:31454063 PMID:29569260 PMID:21194380 RGD:24922201, RGD:24922202 NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
JBrowse link
G Adnp activity-dependent neuroprotector homeobox decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of ADNP protein CTD PMID:28073184 NCBI chr 3:156,886,921...156,921,500
Ensembl chr 3:156,891,381...156,917,312
JBrowse link
G Aebp2 AE binding protein 2 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of AEBP2 protein CTD PMID:28073184 NCBI chr 4:173,527,881...173,593,100
Ensembl chr 4:173,528,344...173,593,100
JBrowse link
G Agfg1 ArfGAP with FG repeats 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of AGFG1 protein CTD PMID:28073184 NCBI chr 9:84,124,878...84,178,149
Ensembl chr 9:84,125,120...84,178,128
JBrowse link
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT2 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of AGPAT2 mRNA CTD PMID:30547786 NCBI chr 3:9,416,842...9,428,567
Ensembl chr 3:9,416,843...9,428,371
JBrowse link
G Agpat5 1-acylglycerol-3-phosphate O-acyltransferase 5 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT5 mRNA CTD PMID:30547786 NCBI chr16:70,939,480...70,985,761
Ensembl chr16:70,943,135...70,985,560
JBrowse link
G Ahdc1 AT hook, DNA binding motif, containing 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of AHDC1 protein CTD PMID:28073184 NCBI chr 5:145,228,228...145,294,170
Ensembl chr 5:145,228,227...145,294,145
JBrowse link
G Ahnak AHNAK nucleoprotein decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of AHNAK protein CTD PMID:28073184 NCBI chr 1:205,882,223...205,970,934
Ensembl chr 1:205,882,273...205,970,926
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO [Palmitic Acid co-treated with Arsenic] affects the expression of AHR mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AHR mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of AHR mRNA CTD PMID:30547786 PMID:33736254 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akap1 A-kinase anchoring protein 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of AKAP1 protein CTD PMID:28073184 NCBI chr10:73,621,021...73,654,123
Ensembl chr10:73,621,883...73,653,896
JBrowse link
G Akap13 A-kinase anchoring protein 13 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of AKAP13 protein CTD PMID:28073184 NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions
increases phosphorylation
EXP
ISO
Palmitic Acid results in decreased phosphorylation of AKT1 protein
[Oleic Acid co-treated with Palmitic Acid] results in decreased phosphorylation of AKT1 protein
Palmitic Acid results in increased phosphorylation of AKT1 protein
4-phenylbutyric acid inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; [Palmitic Acid co-treated with Arsenic] affects the expression of AKT1 mRNA; ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; Palmitic Acid inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]; Palmitic Acid inhibits the reaction [TNF protein results in increased phosphorylation of AKT1 protein]; STF 083010 inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]
geniposide inhibits the reaction [Palmitic Acid results in decreased phosphorylation of AKT1 protein]; Palmitic Acid inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]
CTD PMID:22683933 PMID:22713545 PMID:22819839 PMID:26847930 PMID:30362509 More... NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt1s1 AKT1 substrate 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of AKT1S1 protein CTD PMID:28073184 NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677
JBrowse link
G Alb albumin multiple interactions
affects binding
ISO [ALB protein binds to Palmitic Acid] promotes the reaction [ALB protein results in increased reduction of Dithionitrobenzoic Acid]; [ALB protein binds to Palmitic Acid] promotes the reaction [Pyruvaldehyde results in increased oxidation of ALB protein]; [ALB protein modified form binds to Palmitic Acid] which results in decreased reduction of Dithionitrobenzoic Acid; Palmitic Acid inhibits the reaction [Fenoprofen binds to ALB protein]
ALB protein binds to Palmitic Acid; Palmitic Acid binds to ALB protein
CTD PMID:9470966 PMID:12044178 PMID:25451573 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions
increases expression
EXP acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of ALPL mRNA]; CYBA mutant form inhibits the reaction [Palmitic Acid results in increased expression of ALPL mRNA]; U 0126 inhibits the reaction [Palmitic Acid results in increased expression of ALPL mRNA] CTD PMID:24080574 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Ampd2 adenosine monophosphate deaminase 2 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of AMPD2 protein CTD PMID:28073184 NCBI chr 2:195,707,609...195,720,454
Ensembl chr 2:195,707,610...195,720,271
JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANGPTL4 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ANGPTL4 mRNA CTD PMID:30547786 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Anln anillin, actin binding protein decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of ANLN protein CTD PMID:28073184 NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538
JBrowse link
G Anxa2 annexin A2 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANXA2 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ANXA2 mRNA CTD PMID:30547786 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Apex2 apurinic/apyrimidinic endodeoxyribonuclease 2 multiple interactions ISO [Palmitic Acid co-treated with Arsenic] affects the expression of APEX2 mRNA CTD PMID:33736254 NCBI chr  X:19,425,684...19,508,459
Ensembl chr  X:19,487,419...19,508,439
JBrowse link
G Apob apolipoprotein B multiple interactions EXP [Oleic Acid co-treated with Palmitic Acid] results in increased expression of APOB mRNA; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of APOB mRNA] CTD PMID:26854922 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G App amyloid beta precursor protein multiple interactions
affects expression
ISO [Palmitic Acid co-treated with Arsenic] affects the expression of APP mRNA
Palmitic Acid affects the expression of APP mRNA
CTD PMID:33736254 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Arg1 arginase 1 multiple interactions
decreases expression
affects expression
EXP
ISO
AICA ribonucleotide inhibits the reaction [Palmitic Acid results in decreased expression of ARG1 mRNA]; Metformin inhibits the reaction [Palmitic Acid results in decreased expression of ARG1 mRNA]; resveratrol inhibits the reaction [Palmitic Acid results in decreased expression of ARG1 mRNA]; Salicylic Acid inhibits the reaction [Palmitic Acid results in decreased expression of ARG1 mRNA]
Palmitic Acid results in decreased expression of ARG1 protein
amlexanox affects the reaction [Palmitic Acid affects the expression of ARG1 mRNA]; amlexanox inhibits the reaction [Palmitic Acid results in decreased expression of ARG1 protein]; mifobate affects the reaction [Palmitic Acid affects the expression of ARG1 mRNA]
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ARG1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ARG1 mRNA
CTD PMID:25108154 PMID:30547786 PMID:32905826 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arhgef12 Rho guanine nucleotide exchange factor 12 affects phosphorylation ISO Palmitic Acid affects the phosphorylation of ARHGEF12 protein CTD PMID:28073184 NCBI chr 8:43,350,070...43,475,404
Ensembl chr 8:43,353,799...43,476,366
JBrowse link
G Arid1a AT-rich interaction domain 1A decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of ARID1A protein CTD PMID:28073184 NCBI chr 5:145,908,181...145,981,609
Ensembl chr 5:145,908,181...145,985,564
JBrowse link
G Arl6ip4 ADP-ribosylation factor like GTPase 6 interacting protein 4 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of ARL6IP4 protein CTD PMID:28073184 NCBI chr12:32,479,623...32,481,768
Ensembl chr12:32,479,625...32,481,799
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like decreases expression ISO Palmitic Acid results in decreased expression of ARNTL mRNA; Palmitic Acid results in decreased expression of ARNTL protein CTD PMID:24442997 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Arvcf ARVCF, delta catenin family member decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of ARVCF protein CTD PMID:28073184 NCBI chr11:82,588,137...82,645,805
Ensembl chr11:82,587,881...82,645,805
JBrowse link
G Asb2 ankyrin repeat and SOCS box-containing 2 increases expression ISO Palmitic Acid results in increased expression of ASB2 mRNA CTD PMID:32347412 NCBI chr 6:122,474,754...122,511,014
Ensembl chr 6:122,474,756...122,510,854
JBrowse link
G Asxl2 ASXL transcriptional regulator 2 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of ASXL2 protein CTD PMID:28073184 NCBI chr 6:26,425,017...26,514,899
Ensembl chr 6:26,425,954...26,507,477
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions ISO [Palmitic Acid co-treated with Arsenic] affects the expression of ATF2 mRNA CTD PMID:33736254 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Palmitic Acid results in increased expression of ATF4 protein CTD PMID:30208301 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions ISO 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of ATF6 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ATF6 mRNA CTD PMID:32369900 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atf7 activating transcription factor 7 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of ATF7 protein CTD PMID:28073184 NCBI chr 7:133,660,491...133,750,902
Ensembl chr 7:133,663,294...133,750,848
JBrowse link
G Atf7ip activating transcription factor 7 interacting protein decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of ATF7IP protein CTD PMID:28073184 NCBI chr 4:169,385,872...169,471,652
Ensembl chr 4:169,385,872...169,471,650
JBrowse link
G Atg10 autophagy related 10 multiple interactions ISO [Palmitic Acid co-treated with Arsenic] affects the expression of ATG10 mRNA CTD PMID:33736254 NCBI chr 2:22,109,304...22,398,313
Ensembl chr 2:22,108,426...22,398,233
JBrowse link
G Atg5 autophagy related 5 multiple interactions ISO
EXP
ATG5 protein promotes the reaction [resveratrol inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]]
ATG5 protein promotes the reaction [C1QTNF9 protein inhibits the reaction [Palmitic Acid results in increased expression of CASP3 protein modified form]]
CTD PMID:25943029 PMID:32278738 NCBI chr20:47,798,222...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atg7 autophagy related 7 decreases expression
multiple interactions
ISO Palmitic Acid results in decreased expression of ATG7 protein
trigonelline inhibits the reaction [Palmitic Acid results in decreased expression of ATG7 protein]
ATG7 protein affects the reaction [trigonelline inhibits the reaction [Palmitic Acid results in increased expression of PPARG protein]]; ATG7 protein affects the reaction [trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]]; trigonelline inhibits the reaction [Palmitic Acid results in decreased expression of ATG7 protein]
CTD PMID:30208301 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Atp11b ATPase phospholipid transporting 11B (putative) decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of ATP11B protein CTD PMID:28073184 NCBI chr 2:118,585,348...118,691,076
Ensembl chr 2:118,585,342...118,690,232
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions ISO ATP2A2 protein promotes the reaction [7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased expression of XBP1 mRNA alternative form]] CTD PMID:29414781 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C multiple interactions ISO [Palmitic Acid co-treated with Arsenic] affects the expression of ATP6V0C mRNA CTD PMID:33736254 NCBI chr10:13,196,204...13,202,580
Ensembl chr10:13,196,204...13,201,500
JBrowse link
G Atp7a ATPase copper transporting alpha increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of ATP7A protein CTD PMID:28073184 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G B4galt5 beta-1,4-galactosyltransferase 5 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of B4GALT5 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of B4GALT5 mRNA CTD PMID:30547786 NCBI chr 3:156,018,056...156,033,983
Ensembl chr 3:156,018,053...156,070,074
JBrowse link
G Bad BCL2-associated agonist of cell death increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of BAD protein CTD PMID:28073184 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of BASP1 protein CTD PMID:28073184 NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
affects expression
multiple interactions
ISO
EXP
Palmitic Acid results in increased expression of BAX
Palmitic Acid affects the expression of BAX mRNA
amlexanox inhibits the reaction [Palmitic Acid results in increased expression of BAX protein]
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of BAX mRNA]; [Palmitic Acid co-treated with Arsenic] affects the expression of BAX mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of BAX mRNA
CTD PMID:15945276 PMID:32369900 PMID:32905826 PMID:33736254 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions ISO [Palmitic Acid co-treated with Glucose] results in increased expression of BBC3 mRNA; SIRT1 protein mutant form inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased expression of BBC3 mRNA] CTD PMID:24451382 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO
EXP
Palmitic Acid results in decreased expression of BCL2
Palmitic Acid results in decreased expression of BCL2 protein
amlexanox inhibits the reaction [Palmitic Acid results in decreased expression of BCL2 protein]
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of BCL2 mRNA]; [Palmitic Acid co-treated with Arsenic] results in increased expression of BCL2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of BCL2 mRNA
CTD PMID:15945276 PMID:32369900 PMID:32905826 PMID:33736254 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l13 BCL2 like 13 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of BCL2L13 protein CTD PMID:28073184 NCBI chr 4:154,056,116...154,112,890
Ensembl chr 4:154,056,127...154,108,985
JBrowse link
G Bcl3 BCL3, transcription coactivator decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of BCL3 protein CTD PMID:28073184 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
JBrowse link
G Bcl9l BCL9 like increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of BCL9L protein CTD PMID:28073184 NCBI chr 8:44,811,977...44,840,611
Ensembl chr 8:44,811,977...44,840,611
JBrowse link
G Becn1 beclin 1 multiple interactions
decreases expression
ISO [Palmitic Acid co-treated with Arsenic] affects the expression of BECN1 mRNA; BECN1 protein promotes the reaction [Resveratrol inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]]; trigonelline inhibits the reaction [Palmitic Acid results in decreased expression of BECN1 protein] CTD PMID:25943029 PMID:30208301 PMID:33736254 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bet1l Bet1 golgi vesicular membrane trafficking protein-like decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of BET1L protein CTD PMID:28073184 NCBI chr 1:195,930,165...195,935,072
Ensembl chr 1:195,931,411...195,935,040
JBrowse link
G Bex2 brain expressed X-linked 2 increases expression ISO Palmitic Acid results in increased expression of BEX2 mRNA CTD PMID:32347412 NCBI chr  X:99,019,847...99,021,375
Ensembl chr  X:99,019,000...99,021,503
JBrowse link
G Bex4 brain expressed, X-linked 4 increases expression ISO Palmitic Acid results in increased expression of BEX4 mRNA CTD PMID:32347412 NCBI chr  X:99,132,076...99,133,413
Ensembl chr  X:99,131,942...99,133,531
JBrowse link
G Bfar bifunctional apoptosis regulator multiple interactions ISO [Palmitic Acid co-treated with Arsenic] affects the expression of BFAR mRNA CTD PMID:33736254 NCBI chr10:1,552,019...1,585,040
Ensembl chr10:1,552,072...1,585,038
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions
increases expression
EXP acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of BGLAP mRNA]; CYBA mutant form inhibits the reaction [Palmitic Acid results in increased expression of BGLAP mRNA]; U 0126 inhibits the reaction [Palmitic Acid results in increased expression of BGLAP mRNA] CTD PMID:24080574 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO [Palmitic Acid co-treated with Arsenic] affects the expression of BID mRNA CTD PMID:33736254 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bod1l1 biorientation of chromosomes in cell division 1-like 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of BOD1L1 protein CTD PMID:28073184 NCBI chr14:69,108,483...69,163,255
Ensembl chr14:69,108,491...69,162,490
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of BRAF protein CTD PMID:28073184 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Btg2 BTG anti-proliferation factor 2 multiple interactions ISO [Palmitic Acid co-treated with Arsenic] affects the expression of BTG2 mRNA CTD PMID:33736254 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Bysl bystin-like increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of BYSL protein CTD PMID:28073184 NCBI chr 9:13,382,806...13,392,557
Ensembl chr 9:13,382,557...13,394,339
JBrowse link
G C1qtnf9 C1q and TNF related 9 multiple interactions
decreases response to substance
EXP ATG5 protein promotes the reaction [C1QTNF9 protein inhibits the reaction [Palmitic Acid results in increased expression of CASP3 protein modified form]]; C1QTNF9 protein promotes the reaction [Palmitic Acid results in increased expression of MAP1LC3B protein modified form]
C1QTNF9 protein results in decreased susceptibility to Palmitic Acid
CTD PMID:32278738 NCBI chr15:34,907,791...34,922,985
Ensembl chr15:34,911,286...34,922,980
JBrowse link
G Camsap2 calmodulin regulated spectrin-associated protein family, member 2 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of CAMSAP2 protein CTD PMID:28073184 NCBI chr13:47,723,121...47,802,597
Ensembl chr13:47,723,121...47,802,597
JBrowse link
G Casp1 caspase 1 multiple interactions
increases expression
ISO
EXP
CA 074 methyl ester inhibits the reaction [Palmitic Acid results in increased cleavage of CASP1 protein]; NLRP3 inhibits the reaction [Palmitic Acid results in increased cleavage of CASP1 protein]; Palmitic Acid results in increased cleavage of and affects the localization of CASP1 protein
imoxin inhibits the reaction [Palmitic Acid results in increased expression of CASP1 protein]
CTD PMID:27689324 PMID:30259999 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 increases activity
affects expression
increases cleavage
increases expression
multiple interactions
EXP
ISO
Palmitic Acid results in increased activity of CASP3 protein
Palmitic Acid affects the expression of CASP3 mRNA
Palmitic Acid results in increased cleavage of CASP3 protein
Palmitic Acid results in increased expression of CASP3 mRNA; Palmitic Acid results in increased expression of CASP3 protein; Palmitic Acid results in increased expression of CASP3 protein modified form
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP3 mRNA]; [Fructose co-treated with Palmitic Acid] results in increased activity of CASP3 protein; [Palmitic Acid co-treated with Arsenic] affects the expression of CASP3 mRNA; [Palmitic Acid co-treated with Glucose] results in increased cleavage of CASP3 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP3 mRNA; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [alpidem results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Clomipramine results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Clozapine results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Cyclosporine results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Dipyridamole results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Estrone results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [fipexide results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Flecainide results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Fluoxetine results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Fluvoxamine results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Imipramine results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Loratadine results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Mitoxantrone results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [nefazodone results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Nimodipine results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Nortriptyline results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Phentolamine results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Propranolol results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Pyrimethamine results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Riluzole results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Risperidone results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Spironolactone results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Ticlopidine results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Troglitazone results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [zileuton results in increased activity of CASP3 protein]; SIRT1 protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased cleavage of CASP3 protein]
[TO-901317 co-treated with Alitretinoin] promotes the reaction [Palmitic Acid results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of CASP3 mRNA]; ATG5 protein promotes the reaction [C1QTNF9 protein inhibits the reaction [Palmitic Acid results in increased expression of CASP3 protein modified form]]; geniposide inhibits the reaction [Palmitic Acid results in increased expression of and results in increased activity of CASP3 protein]; imoxin inhibits the reaction [Palmitic Acid results in increased expression of CASP3 mRNA]; imoxin inhibits the reaction [Palmitic Acid results in increased expression of CASP3 protein]; Palmitic Acid results in increased cleavage of and results in increased activity of CASP3 protein; Palmitic Acid results in increased expression of and results in increased activity of CASP3 protein; parthenolide inhibits the reaction [Palmitic Acid results in increased expression of CASP3 mRNA]; pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased expression of CASP3 mRNA]; pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased expression of CASP3 protein]; SCD1 protein inhibits the reaction [Palmitic Acid results in increased activity of CASP3 protein]; TO-901317 promotes the reaction [Palmitic Acid results in increased activity of CASP3 protein]
amlexanox inhibits the reaction [Palmitic Acid results in increased cleavage of CASP3 protein]; Palmitic Acid results in decreased expression of and results in increased cleavage of CASP3 protein; pyrrolidine dithiocarbamic acid inhibits the reaction [Palmitic Acid results in decreased expression of and results in increased cleavage of CASP3 protein]
CTD PMID:17194744 PMID:21687928 PMID:22413010 PMID:22700542 PMID:22819839 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 multiple interactions
increases activity
EXP
ISO
[TO-901317 co-treated with alitretinoin] promotes the reaction [Palmitic Acid results in increased activity of CASP7 protein]; TO-901317 promotes the reaction [Palmitic Acid results in increased activity of CASP7 protein]
Palmitic Acid promotes the reaction [alpidem results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Clomipramine results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Clozapine results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Cyclosporine results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Dipyridamole results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Estrone results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [fipexide results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Flecainide results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Fluoxetine results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Fluvoxamine results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Imipramine results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Loratadine results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Mitoxantrone results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [nefazodone results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Nimodipine results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Nortriptyline results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Phentolamine results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Pyrimethamine results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Riluzole results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Risperidone results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Spironolactone results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Ticlopidine results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Troglitazone results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [zileuton results in increased activity of CASP7 protein]
CTD PMID:17194744 PMID:22413010 PMID:22700542 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp9 caspase 9 multiple interactions ISO 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP9 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP9 mRNA CTD PMID:32369900 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions EXP
ISO
[Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased activity of CAT protein; [Oleic Acid co-treated with Palmitic Acid] results in increased activity of CAT protein
[Palmitic Acid co-treated with Arsenic] affects the expression of CAT mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CAT mRNA
CTD PMID:26854922 PMID:30547786 PMID:33736254 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav1 caveolin 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of CAV1 protein CTD PMID:28073184 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cav2 caveolin 2 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid] affects the expression of CAV2 mRNA CTD PMID:30547786 NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244
JBrowse link
G Cbx3 chromobox 3 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of CBX3 protein CTD PMID:28073184 NCBI chr 4:80,545,450...80,559,284
Ensembl chr 4:80,546,010...80,559,283
JBrowse link
G Ccdc6 coiled-coil domain containing 6 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of CCDC6 protein CTD PMID:28073184 NCBI chr20:18,432,177...18,528,186
Ensembl chr20:18,433,695...18,528,658
JBrowse link
G Ccdc9 coiled-coil domain containing 9 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of CCDC9 protein CTD PMID:28073184 NCBI chr 1:76,978,312...76,991,673
Ensembl chr 1:76,974,091...76,991,607
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
EXP
ISO
AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of CCL2 mRNA]; Metformin inhibits the reaction [Palmitic Acid results in increased expression of CCL2 mRNA]; resveratrol inhibits the reaction [Palmitic Acid results in increased expression of CCL2 mRNA]; Salicylic Acid inhibits the reaction [Palmitic Acid results in increased expression of CCL2 mRNA]
(R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CCL2 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein; Bezafibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]
Palmitic Acid results in increased expression of CCL2 mRNA; Palmitic Acid results in increased expression of CCL2 protein
Quercetin inhibits the reaction [Palmitic Acid results in increased expression of CCL2 mRNA]; Quercetin inhibits the reaction [Palmitic Acid results in increased expression of CCL2 protein]
CTD PMID:25108154 PMID:25614714 PMID:32613381 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
increases expression
ISO AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of CCL3 mRNA]; Bezafibrate inhibits the reaction [Palmitic Acid results in increased expression of CCL3 mRNA]; Capsaicin inhibits the reaction [Palmitic Acid results in increased expression of CCL3 mRNA]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [Capsaicin inhibits the reaction [Palmitic Acid results in increased expression of CCL3 mRNA]] CTD PMID:21745629 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CCL5 mRNA CTD PMID:32613381 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Cd14 CD14 molecule increases expression
multiple interactions
ISO Palmitic Acid results in increased expression of CD14 mRNA
amlexanox inhibits the reaction [Palmitic Acid results in increased expression of CD14 mRNA]
CTD PMID:32905826 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd36 CD36 molecule increases expression
multiple interactions
ISO Palmitic Acid results in increased expression of CD36 protein
(R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]
trigonelline inhibits the reaction [Palmitic Acid results in increased expression of CD36 protein]
CTD PMID:30208301 PMID:32613381 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cd68 Cd68 molecule increases expression
multiple interactions
ISO Palmitic Acid results in increased expression of CD68 mRNA
amlexanox inhibits the reaction [Palmitic Acid results in increased expression of CD68 mRNA]
CTD PMID:32905826 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
JBrowse link
G Cdc42ep4 CDC42 effector protein 4 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of CDC42EP4 protein CTD PMID:28073184 NCBI chr10:98,772,613...98,797,924
Ensembl chr10:98,772,495...98,797,695
JBrowse link
G Cdh15 cadherin 15 increases expression ISO Palmitic Acid results in increased expression of CDH15 mRNA CTD PMID:32347412 NCBI chr19:50,903,757...50,927,151
Ensembl chr19:50,903,638...50,927,105
JBrowse link
G Cdh3 cadherin 3 increases expression ISO Palmitic Acid results in increased expression of CDH3 mRNA CTD PMID:32347412 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CDKN1A mRNA]; [Palmitic Acid co-treated with Glucose] results in increased expression of CDKN1A mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CDKN1A mRNA; SIRT1 protein mutant form inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased expression of CDKN1A mRNA] CTD PMID:24451382 PMID:32369900 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of CDKN1B protein CTD PMID:28073184 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions EXP [Palmitic Acid co-treated with Sincalide] results in increased expression of CEBPA mRNA; [Palmitic Acid co-treated with Sincalide] results in increased expression of CEBPA protein; Quercetin inhibits the reaction [[Sincalide co-treated with Palmitic Acid] results in increased expression of CEBPA protein] CTD PMID:26873426 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions EXP [Palmitic Acid co-treated with Sincalide] results in increased expression of CEBPB mRNA; [Palmitic Acid co-treated with Sincalide] results in increased expression of CEBPB protein; Quercetin inhibits the reaction [[Sincalide co-treated with Palmitic Acid] results in increased expression of CEBPB protein] CTD PMID:26873426 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cep170b centrosomal protein 170B decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of CEP170B protein CTD PMID:28073184 NCBI chr 6:131,780,935...131,806,658
Ensembl chr 6:131,778,957...131,806,658
JBrowse link
G Chaf1a chromatin assembly factor 1 subunit A decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of CHAF1A protein CTD PMID:28073184 NCBI chr 9:873,953...900,701
Ensembl chr 9:874,051...900,654
JBrowse link
G Chchd3 coiled-coil-helix-coiled-coil-helix domain containing 3 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of CHCHD3 protein CTD PMID:28073184 NCBI chr 4:61,360,352...61,616,850
Ensembl chr 4:61,360,353...61,616,847
JBrowse link
G Chd3 chromodomain helicase DNA binding protein 3 affects phosphorylation ISO Palmitic Acid affects the phosphorylation of CHD3 protein CTD PMID:28073184 NCBI chr10:54,063,629...54,090,030
Ensembl chr10:54,063,629...54,090,047
JBrowse link
G Cidec cell death-inducing DFFA-like effector c multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CIDEC protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CIDEC mRNA CTD PMID:30547786 NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of CLIP1 protein CTD PMID:28073184 NCBI chr12:32,910,932...33,017,891
Ensembl chr12:32,910,977...33,017,884
JBrowse link
G Clock clock circadian regulator decreases expression ISO Palmitic Acid results in decreased expression of CLOCK mRNA; Palmitic Acid results in decreased expression of CLOCK protein CTD PMID:24442997 NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400
JBrowse link
G Cnot2 CCR4-NOT transcription complex, subunit 2 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of CNOT2 protein CTD PMID:28073184 NCBI chr 7:52,130,444...52,222,338
Ensembl chr 7:52,130,441...52,223,575
JBrowse link
G Cobll1 cordon-bleu WH2 repeat protein-like 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of COBLL1 protein CTD PMID:28073184 NCBI chr 3:49,753,260...49,915,168
Ensembl chr 3:49,753,262...49,915,194
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of COL1A1 mRNA CTD PMID:26187275 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Coro2b coronin 2B increases expression ISO Palmitic Acid results in increased expression of CORO2B mRNA CTD PMID:32347412 NCBI chr 8:62,906,861...63,017,295
Ensembl chr 8:62,906,867...63,017,302
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A decreases expression
increases methylation
multiple interactions
EXP Palmitic Acid results in decreased expression of COX5A mRNA
Palmitic Acid results in increased methylation of COX5A promoter
decitabine inhibits the reaction [Palmitic Acid results in decreased expression of COX5A mRNA]; decitabine inhibits the reaction [Palmitic Acid results in increased methylation of COX5A promoter]
CTD PMID:25436770 NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions
decreases expression
increases expression
ISO
EXP
(R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of CPT1A protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CPT1A mRNA; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of CPT1A protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CPT1A mRNA; Bezafibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Capsaicin promotes the reaction [Palmitic Acid results in increased expression of CPT1A mRNA]; Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Ivermectin inhibits the reaction [Palmitic Acid results in increased expression of CPT1A mRNA]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Permethrin inhibits the reaction [Palmitic Acid results in increased expression of CPT1A mRNA]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]
Palmitic Acid results in decreased expression of CPT1A mRNA
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of CPT1A mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A protein; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of CPT1A mRNA]; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A protein]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of CPT1A mRNA]; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA]; Triiodothyronine promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA]
amlexanox inhibits the reaction [Palmitic Acid results in decreased expression of CPT1A mRNA]; obeticholic acid promotes the reaction [Palmitic Acid results in increased expression of CPT1A mRNA]
CTD PMID:21745629 PMID:25048947 PMID:26190035 PMID:26655953 PMID:26854922 More... NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO Palmitic Acid inhibits the reaction [SMIM20 protein results in increased phosphorylation of CREB1 protein] CTD PMID:30716364 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crip2 cysteine-rich protein 2 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of CRIP2 protein CTD PMID:28073184 NCBI chr 6:132,221,120...132,226,066
Ensembl chr 6:132,221,082...132,226,065
JBrowse link
G Crybg1 crystallin beta-gamma domain containing 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of CRYBG1 protein CTD PMID:28073184 NCBI chr20:47,425,030...47,496,918
Ensembl chr20:47,426,183...47,621,392
JBrowse link
G Cspp1 centrosome and spindle pole associated protein 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of CSPP1 protein CTD PMID:28073184 NCBI chr 5:9,077,161...9,192,402
Ensembl chr 5:9,077,161...9,193,377
JBrowse link
G Ctnnd1 catenin delta 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of CTNND1 protein CTD PMID:28073184 NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516
JBrowse link
G Ctr9 CTR9 homolog, Paf1/RNA polymerase II complex component decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of CTR9 protein CTD PMID:28073184 NCBI chr 1:165,137,277...165,167,303
Ensembl chr 1:165,137,215...165,167,303
JBrowse link
G Cttn cortactin decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of CTTN protein CTD PMID:28073184 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid] affects the expression of CXCL10 mRNA CTD PMID:30547786 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CXCL2 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of CXCL2 mRNA CTD PMID:30547786 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions EXP CYBA mutant form inhibits the reaction [Palmitic Acid results in increased expression of ALPL mRNA]; CYBA mutant form inhibits the reaction [Palmitic Acid results in increased expression of BGLAP mRNA]; CYBA mutant form inhibits the reaction [Palmitic Acid results in increased expression of RUNX2 mRNA]; CYBA mutant form inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK1 protein]; CYBA mutant form inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK3 protein] CTD PMID:24080574 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cybb cytochrome b-245 beta chain increases expression
multiple interactions
EXP
ISO
Palmitic Acid results in increased expression of CYBB mRNA
geraniol inhibits the reaction [Palmitic Acid results in increased expression of CYBB protein]
acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of CYBB mRNA]; U 0126 inhibits the reaction [Palmitic Acid results in increased expression of CYBB mRNA]
CTD PMID:24080574 PMID:27107694 NCBI chr  X:13,360,583...13,392,517
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO [Fructose co-treated with Palmitic Acid] results in increased expression of CYCS protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of CYCS protein] CTD PMID:32730863 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP24A1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CYP24A1 mRNA CTD PMID:30547786 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP26A1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CYP26A1 mRNA CTD PMID:30547786 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CYP26B1 mRNA CTD PMID:30547786 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases expression
EXP
ISO
[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP2E1 mRNA; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP2E1 mRNA]
Palmitic Acid results in increased expression of CYP2E1 mRNA; Palmitic Acid results in increased expression of CYP2E1 protein
amlexanox inhibits the reaction [Palmitic Acid results in increased expression of CYP2E1 mRNA]; amlexanox inhibits the reaction [Palmitic Acid results in increased expression of CYP2E1 protein]
CTD PMID:26854922 PMID:32905826 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 multiple interactions EXP [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in decreased expression of CYP4A1 mRNA CTD PMID:26854922 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
G Dab2ip DAB2 interacting protein decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of DAB2IP protein CTD PMID:28073184 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280
JBrowse link
G Dapk1 death associated protein kinase 1 multiple interactions ISO [Palmitic Acid co-treated with Arsenic] affects the expression of DAPK1 mRNA CTD PMID:33736254 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
JBrowse link
G Dbn1 drebrin 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of DBN1 protein CTD PMID:28073184 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984
JBrowse link
G Dbnl drebrin-like decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of DBNL protein CTD PMID:28073184 NCBI chr14:80,666,115...80,681,155
Ensembl chr14:80,666,124...80,681,155
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO Palmitic Acid results in increased expression of DDIT3 protein
Palmitic Acid results in increased expression of DDIT3 mRNA
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of DDIT3 mRNA]; [Palmitic Acid co-treated with Arsenic] results in increased expression of DDIT3 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of DDIT3 mRNA; Ivermectin promotes the reaction [Palmitic Acid results in increased expression of DDIT3 protein]; Permethrin inhibits the reaction [Palmitic Acid results in increased expression of DDIT3 mRNA]
7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased expression of DDIT3 protein]; Thapsigargin inhibits the reaction [7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased expression of DDIT3 protein]]
CTD PMID:29414781 PMID:30208301 PMID:30738135 PMID:32369900 PMID:33736254 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddx17 DEAD-box helicase 17 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of DDX17 protein CTD PMID:28073184 NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193
JBrowse link
G Ddx20 DEAD-box helicase 20 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of DDX20 protein CTD PMID:28073184 NCBI chr 2:193,158,761...193,168,484
Ensembl chr 2:193,158,823...193,166,774
JBrowse link
G Ddx24 DEAD-box helicase 24 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of DDX24 protein CTD PMID:28073184 NCBI chr 6:122,564,767...122,582,032
Ensembl chr 6:122,564,767...122,581,927
JBrowse link
G Derl1 derlin 1 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid] affects the expression of DERL1 mRNA CTD PMID:30547786 NCBI chr 7:89,404,413...89,427,095
Ensembl chr 7:89,404,417...89,427,145
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 increases expression
multiple interactions
ISO Palmitic Acid results in increased expression of DGAT1 mRNA
7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased expression of DGAT1 mRNA]; amlexanox inhibits the reaction [Palmitic Acid results in increased expression of DGAT1 mRNA]
CTD PMID:29414781 PMID:32905826 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dhx29 DExH-box helicase 29 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of DHX29 protein CTD PMID:28073184 NCBI chr 2:44,560,653...44,611,450
Ensembl chr 2:44,560,714...44,611,445
JBrowse link
G Dip2b disco-interacting protein 2 homolog B increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of DIP2B protein CTD PMID:28073184 NCBI chr 7:131,174,575...131,350,417
Ensembl chr 7:131,174,567...131,349,092
JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of DKC1 protein CTD PMID:28073184
G Dmxl1 Dmx-like 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of DMXL1 protein CTD PMID:28073184 NCBI chr18:42,993,292...43,163,457
Ensembl chr18:42,993,340...43,163,456
JBrowse link
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of DNAJC15 protein CTD PMID:28073184 NCBI chr15:53,182,060...53,249,675
Ensembl chr15:53,184,855...53,249,675
JBrowse link
G Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of DNAJC6 protein CTD PMID:28073184 NCBI chr 5:116,120,069...116,283,448
Ensembl chr 5:116,119,676...116,283,448
JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO [Fructose co-treated with Palmitic Acid] results in increased expression of DNM1L protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of DNM1L protein] CTD PMID:32730863 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Dnmt1 DNA methyltransferase 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of DNMT1 protein CTD PMID:28073184 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dock7 dedicator of cytokinesis 7 affects phosphorylation ISO Palmitic Acid affects the phosphorylation of DOCK7 protein CTD PMID:28073184 NCBI chr 5:113,599,371...113,782,871
Ensembl chr 5:113,600,198...113,782,813
JBrowse link
G Dot1l DOT1 like histone lysine methyltransferase affects phosphorylation ISO Palmitic Acid affects the phosphorylation of DOT1L protein CTD PMID:28073184 NCBI chr 7:8,917,786...8,959,474
Ensembl chr 7:8,917,786...8,956,475
JBrowse link
G Dpf2 double PHD fingers 2 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of DPF2 protein CTD PMID:28073184 NCBI chr 1:203,183,674...203,199,037
Ensembl chr 1:203,183,686...203,198,983
JBrowse link
G Dst dystonin multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of DST mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of DST mRNA CTD PMID:30547786 NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615
JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of DTL protein CTD PMID:28073184 NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890
JBrowse link
G Dync1h1 dynein cytoplasmic 1 heavy chain 1 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1H1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of DYNC1H1 mRNA CTD PMID:30547786 NCBI chr 6:129,615,208...129,680,888
Ensembl chr 6:129,609,397...129,680,883
JBrowse link
G Dync1i1 dynein cytoplasmic 1 intermediate chain 1 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1I1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of DYNC1I1 mRNA CTD PMID:30547786 NCBI chr 4:33,852,597...34,166,159
Ensembl chr 4:33,852,927...34,166,149
JBrowse link
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of DYNC1LI1 protein CTD PMID:28073184 NCBI chr 8:114,376,649...114,410,297
Ensembl chr 8:114,376,662...114,410,934
JBrowse link
G Dync1li2 dynein, cytoplasmic 1 light intermediate chain 2 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of DYNC1LI2 protein CTD PMID:28073184 NCBI chr19:531,783...554,670
Ensembl chr19:531,812...554,670
JBrowse link
G Edc3 enhancer of mRNA decapping 3 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of EDC3 protein CTD PMID:28073184 NCBI chr 8:58,106,129...58,151,685
Ensembl chr 8:58,106,175...58,151,671
JBrowse link
G Edn1 endothelin 1 increases expression ISO Palmitic Acid results in increased expression of EDN1 mRNA; Palmitic Acid results in increased expression of EDN1 protein CTD PMID:16895544 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Efhd2 EF-hand domain family, member D2 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of EFHD2 protein CTD PMID:28073184 NCBI chr 5:154,160,945...154,176,980
Ensembl chr 5:154,160,946...154,176,980
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid] affects the expression of EGFR mRNA CTD PMID:30547786 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 increases expression ISO Palmitic Acid results in increased expression of EGR1 mRNA CTD PMID:32347412 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 multiple interactions
increases phosphorylation
increases expression
EXP
ISO
imoxin inhibits the reaction [Palmitic Acid results in increased expression of EIF2AK2 mRNA]; imoxin inhibits the reaction [Palmitic Acid results in increased expression of EIF2AK2 protein]
Palmitic Acid results in increased phosphorylation of EIF2AK2 protein
Palmitic Acid results in increased expression of EIF2AK2 mRNA; Palmitic Acid results in increased expression of EIF2AK2 protein
CTD PMID:30259999 PMID:30794626 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions ISO 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of EIF2AK3 mRNA]; [Palmitic Acid co-treated with Oleic Acid] affects the expression of EIF2AK3 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of EIF2AK3 mRNA CTD PMID:30547786 PMID:32369900 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions
increases phosphorylation
ISO 7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased phosphorylation of EIF2S1 protein]; Thapsigargin inhibits the reaction [7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased phosphorylation of EIF2S1 protein]]; trigonelline inhibits the reaction [Palmitic Acid results in increased phosphorylation of EIF2S1 protein] CTD PMID:29414781 PMID:30208301 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Eif4b eukaryotic translation initiation factor 4B decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of EIF4B protein CTD PMID:28073184 NCBI chr 7:133,206,637...133,228,436 JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of EIF4EBP1 protein CTD PMID:28073184 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Eif5b eukaryotic translation initiation factor 5B increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of EIF5B protein CTD PMID:28073184 NCBI chr 9:40,222,769...40,277,482
Ensembl chr 9:40,222,898...40,277,482
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 multiple interactions ISO (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ELOVL6 mRNA; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA] CTD PMID:30547786 PMID:32613381 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
JBrowse link
G Eno3 enolase 3 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ENO3 mRNA CTD PMID:30547786 NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit multiple interactions ISO [Palmitic Acid co-treated with Arsenic] affects the expression of ERCC1 mRNA CTD PMID:33736254 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
JBrowse link
G Erlin1 ER lipid raft associated 1 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ERLIN1 mRNA CTD PMID:30547786 NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases phosphorylation
EXP
ISO
[Palmitic Acid co-treated with Sincalide] results in increased expression of ERN1 mRNA; [Palmitic Acid co-treated with Sincalide] results in increased expression of ERN1 protein; Quercetin inhibits the reaction [[Sincalide co-treated with Palmitic Acid] results in increased expression of ERN1 protein]
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of ERN1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ERN1 mRNA; Deferoxamine promotes the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein]; ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein]; Sirolimus inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein]
7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein]; baicalin inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein]; Thapsigargin inhibits the reaction [7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein]]; ursodoxicoltaurine inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein]
CTD PMID:26873426 PMID:29031535 PMID:29414781 PMID:32283200 PMID:32369900 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Esf1 ESF1 nucleolar pre-rRNA processing protein homolog increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of ESF1 protein CTD PMID:28073184 NCBI chr 3:127,454,744...127,507,941
Ensembl chr 3:127,454,811...127,507,817
JBrowse link
G Exosc9 exosome component 9 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of EXOSC9 protein CTD PMID:28073184 NCBI chr 2:119,416,028...119,426,981
Ensembl chr 2:119,388,715...119,427,051
JBrowse link
G Fabp1 fatty acid binding protein 1 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid] affects the expression of FABP1 mRNA CTD PMID:30547786 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fam117b family with sequence similarity 117, member B decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of FAM117B protein CTD PMID:28073184 NCBI chr 9:61,340,291...61,418,531
Ensembl chr 9:61,340,249...61,408,483
JBrowse link
G Fam120a family with sequence similarity 120A decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of FAM120A protein CTD PMID:28073184 NCBI chr17:15,684,233...15,774,964
Ensembl chr17:15,684,233...15,774,964
JBrowse link
G Fam83b family with sequence similarity 83, member B decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of FAM83B protein CTD PMID:28073184 NCBI chr 8:77,287,351...77,363,795
Ensembl chr 8:77,287,351...77,363,795
JBrowse link
G Fas Fas cell surface death receptor increases expression
multiple interactions
ISO
EXP
Palmitic Acid results in increased expression of FAS protein
[Palmitic Acid co-treated with Arsenic] affects the expression of FAS mRNA; Palmitic Acid inhibits the reaction [Permethrin results in decreased expression of FAS mRNA]
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS mRNA; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS mRNA]
CTD PMID:21687928 PMID:26190035 PMID:30738135 PMID:33736254 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fasn fatty acid synthase multiple interactions
increases phosphorylation
increases expression
ISO
EXP
acanthoic acid inhibits the reaction [Palmitic Acid results in increased expression of FASN mRNA]; amlexanox inhibits the reaction [Palmitic Acid results in increased expression of FASN mRNA]; GW 3965 inhibits the reaction [Palmitic Acid results in increased expression of FASN mRNA]; obeticholic acid inhibits the reaction [Palmitic Acid results in increased expression of FASN mRNA]; Orlistat inhibits the reaction [FASN protein results in increased chemical synthesis of Palmitic Acid]
[Fructose co-treated with Palmitic Acid] results in increased expression of FASN protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of FASN protein]
Palmitic Acid results in increased phosphorylation of FASN protein
[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of FASN mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of FASN mRNA
Palmitic Acid results in increased expression of FASN mRNA; Palmitic Acid results in increased expression of FASN protein
CTD PMID:21213365 PMID:26655953 PMID:26854922 PMID:28073184 PMID:29414781 More... NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbxo32 F-box protein 32 increases expression
multiple interactions
ISO Palmitic Acid results in increased expression of FBXO32 mRNA
Quercetin inhibits the reaction [Palmitic Acid results in increased expression of FBXO32 mRNA]
CTD PMID:25614714 NCBI chr 7:89,731,626...89,764,761
Ensembl chr 7:89,730,232...89,765,436
JBrowse link
G Fbxw9 F-box and WD repeat domain containing 9 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of FBXW9 protein CTD PMID:28073184 NCBI chr19:23,090,534...23,097,439
Ensembl chr19:23,090,534...23,097,439
JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions ISO 3-(4-chlorophenyl)-N-methyl-N'-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboxamidine analog inhibits the reaction [[osteum co-treated with Palmitic Acid] results in increased expression of FGF2 mRNA]; [osteum co-treated with Palmitic Acid] results in increased expression of FGF2 mRNA CTD PMID:31454063 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgf21 fibroblast growth factor 21 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FGF21 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of FGF21 mRNA CTD PMID:30547786 NCBI chr 1:96,083,495...96,084,738
Ensembl chr 1:96,083,441...96,090,454
JBrowse link
G Fis1 fission, mitochondrial 1 multiple interactions ISO 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of FIS1 mRNA]; [Fructose co-treated with Palmitic Acid] results in increased expression of FIS1 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of FIS1 mRNA; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of FIS1 protein] CTD PMID:32369900 PMID:32730863 NCBI chr12:19,708,558...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Fkbp15 FKBP prolyl isomerase family member 15 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of FKBP15 protein CTD PMID:28073184 NCBI chr 5:75,750,786...75,815,038
Ensembl chr 5:75,750,787...75,814,990
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of FKBP5 protein CTD PMID:28073184 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
JBrowse link
G Flot1 flotillin 1 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FLOT1 mRNA CTD PMID:30547786 NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978
JBrowse link
G Foxa1 forkhead box A1 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of FOXA1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of FOXA1 mRNA CTD PMID:30547786 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
JBrowse link
G Foxo1 forkhead box O1 multiple interactions
decreases phosphorylation
increases localization
ISO
EXP
[GCG protein co-treated with candesartan] inhibits the reaction [Palmitic Acid results in decreased phosphorylation of FOXO1 protein]; [Oleic Acid co-treated with Palmitic Acid] results in decreased phosphorylation of FOXO1 protein; candesartan inhibits the reaction [Palmitic Acid results in decreased phosphorylation of FOXO1 protein]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC protein]]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NFE2L2 mRNA]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of TFAM mRNA]; GCG protein inhibits the reaction [Palmitic Acid results in decreased phosphorylation of FOXO1 protein]
geniposide inhibits the reaction [Palmitic Acid results in decreased phosphorylation of FOXO1 protein]; resveratrol inhibits the reaction [Palmitic Acid results in increased localization of FOXO1 protein]
CTD PMID:21255808 PMID:22819839 PMID:22968147 PMID:26847930 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of FRS2 protein CTD PMID:28073184 NCBI chr 7:52,711,255...52,792,758
Ensembl chr 7:52,711,257...52,792,743
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression
multiple interactions
ISO Palmitic Acid results in increased expression of FTH1 protein
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of FTH1 protein; ferric ammonium citrate promotes the reaction [Palmitic Acid results in increased expression of FTH1 protein]; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of FTH1 protein]
CTD PMID:32283200 PMID:32976958 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Fubp1 far upstream element binding protein 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of FUBP1 protein CTD PMID:28073184 NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
JBrowse link
G Fxr2 FMR1 autosomal homolog 2 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of FXR2 protein CTD PMID:28073184 NCBI chr10:54,350,577...54,370,964
Ensembl chr10:54,350,131...54,370,964
JBrowse link
G G3bp1 G3BP stress granule assembly factor 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of G3BP1 protein CTD PMID:28073184 NCBI chr10:39,586,864...39,620,268
Ensembl chr10:39,586,864...39,620,268
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC protein]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC protein]]] CTD PMID:26847930 NCBI chr10:86,307,400...86,318,766 JBrowse link
G Gcg glucagon multiple interactions ISO [GCG protein co-treated with candesartan] inhibits the reaction [Palmitic Acid results in decreased phosphorylation of FOXO1 protein]; [GCG protein co-treated with candesartan] inhibits the reaction [Palmitic Acid results in decreased phosphorylation of IRS2 protein]; GCG protein inhibits the reaction [Palmitic Acid results in decreased phosphorylation of FOXO1 protein]; GCG protein inhibits the reaction [Palmitic Acid results in decreased phosphorylation of IRS2 protein]; isosteviol inhibits the reaction [Palmitic Acid promotes the reaction [Glucose results in increased secretion of GCG protein]]; Palmitic Acid promotes the reaction [Glucose results in increased secretion of GCG protein] CTD PMID:21255808 PMID:22479612 NCBI chr 3:47,113,914...47,122,929
Ensembl chr 3:47,113,914...47,122,929
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression EXP Palmitic Acid results in increased expression of GCLC mRNA CTD PMID:28027979 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid] affects the expression of GGT1 mRNA CTD PMID:30547786 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Gigyf1 GRB10 interacting GYF protein 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of GIGYF1 protein CTD PMID:28073184 NCBI chr12:19,166,070...19,181,570
Ensembl chr12:19,166,088...19,175,023
JBrowse link
G Glcci1 glucocorticoid induced 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of GLCCI1 protein CTD PMID:28073184 NCBI chr 4:36,307,956...36,635,614
Ensembl chr 4:36,307,903...36,635,612
JBrowse link
G Glrx glutaredoxin multiple interactions ISO GLRX protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] promotes the reaction [Glutathione binds to SIRT1 protein]]; GLRX protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased oxidation of and results in decreased activity of SIRT1 protein] CTD PMID:24451382 NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
JBrowse link
G Gls glutaminase decreases oxidation ISO GLS protein results in decreased oxidation of Palmitic Acid CTD PMID:31040181 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
JBrowse link
G Glud1 glutamate dehydrogenase 1 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of GLUD1 mRNA CTD PMID:30547786 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
JBrowse link
G Golga4 golgin A4 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of GOLGA4 protein CTD PMID:28073184 NCBI chr 8:118,208,200...118,285,003 JBrowse link
G Gosr1 golgi SNAP receptor complex member 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of GOSR1 protein CTD PMID:28073184 NCBI chr10:61,570,499...61,607,287
Ensembl chr10:61,450,494...61,607,177
Ensembl chr10:61,450,494...61,607,177
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial increases expression ISO Palmitic Acid results in increased expression of GPAM mRNA CTD PMID:29414781 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Gpatch8 G patch domain containing 8 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of GPATCH8 protein CTD PMID:28073184 NCBI chr10:87,432,020...87,512,595
Ensembl chr10:87,433,266...87,512,419
JBrowse link
G Gpr173 G-protein coupled receptor 173 multiple interactions
decreases expression
ISO 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Palmitic Acid results in decreased expression of GPR173 mRNA] CTD PMID:30716364 NCBI chr  X:21,446,261...21,471,497 JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO [Cisplatin co-treated with Palmitic Acid] results in increased expression of GPT protein; [Palmitic Acid co-treated with Oleic Acid] results in increased activity of GPT protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased activity of GPT protein] CTD PMID:28073184 PMID:32976958 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression
multiple interactions
ISO Palmitic Acid results in decreased expression of GPX1 mRNA
[Palmitic Acid co-treated with Arsenic] affects the expression of GPX1 mRNA; Rosiglitazone inhibits the reaction [Palmitic Acid results in decreased expression of GPX1 mRNA]
CTD PMID:18155663 PMID:33736254 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression EXP Palmitic Acid results in increased expression of GPX2 mRNA CTD PMID:28027979 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression
multiple interactions
EXP
ISO
Palmitic Acid results in increased expression of GPX4 mRNA
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein]
CTD PMID:28027979 PMID:32976958 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha affects phosphorylation ISO Palmitic Acid affects the phosphorylation of GSK3A protein CTD PMID:28073184 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO Palmitic Acid inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of GSK3B protein] CTD PMID:30362509 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO [Palmitic Acid co-treated with Arsenic] results in increased expression of GSR mRNA CTD PMID:33736254 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid] affects the expression of GSTA1 mRNA CTD PMID:30547786 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gtf2i general transcription factor II I decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of GTF2I protein CTD PMID:28073184 NCBI chr12:22,400,933...22,476,243
Ensembl chr12:22,401,431...22,476,243
JBrowse link
G Gtf3c1 general transcription factor IIIC subunit 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of GTF3C1 protein CTD PMID:28073184 NCBI chr 1:180,203,995...180,270,201
Ensembl chr 1:180,203,995...180,270,201
JBrowse link
G Gtse1 G-2 and S-phase expressed 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of GTSE1 protein CTD PMID:28073184 NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806
JBrowse link
G Gys1 glycogen synthase 1 multiple interactions ISO Palmitic Acid inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of GYS1 protein] CTD PMID:30362509 NCBI chr 1:95,915,443...95,935,292
Ensembl chr 1:95,915,443...95,935,292
JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of HACD3 protein CTD PMID:28073184 NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507
JBrowse link
G Hal histidine ammonia lyase increases expression ISO Palmitic Acid results in increased expression of HAL mRNA CTD PMID:17658692 NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
JBrowse link
G Hamp hepcidin antimicrobial peptide increases expression ISO Palmitic Acid results in increased expression of HAMP mRNA CTD PMID:17658692 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Hbp1 HMG-box transcription factor 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of HBP1 protein CTD PMID:28073184 NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787
JBrowse link
G Hdgf heparin binding growth factor decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of HDGF protein CTD PMID:28073184 NCBI chr 2:173,370,147...173,379,756
Ensembl chr 2:173,370,465...173,379,747
JBrowse link
G Herc2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of HERC2 protein CTD PMID:28073184 NCBI chr 1:106,904,789...107,110,997
Ensembl chr 1:106,880,084...107,108,134
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HIF1A protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of HIF1A protein CTD PMID:30547786 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HILPDA protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of HILPDA protein CTD PMID:30547786 NCBI chr 4:57,871,076...57,875,206 JBrowse link
G Hivep1 HIVEP zinc finger 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of HIVEP1 protein CTD PMID:28073184 NCBI chr17:22,585,016...22,714,517
Ensembl chr17:22,585,016...22,711,956
JBrowse link
G Hmgb1 high mobility group box 1 increases secretion ISO Palmitic Acid results in increased secretion of HMGB1 protein CTD PMID:27689324 NCBI chr12:5,973,062...5,978,565 JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO [[Palmitic Acid co-treated with Oleic Acid] co-treated with IFNA2 protein alternative form] results in decreased expression of HMGCR protein CTD PMID:31299271 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
EXP
ISO
Palmitic Acid results in increased expression of HMOX1 mRNA
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein]
[amlexanox co-treated with Palmitic Acid] results in increased expression of HMOX1 mRNA
CTD PMID:28027979 PMID:32905826 PMID:32976958 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid] affects the expression of HNF4A mRNA CTD PMID:30547786 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of HNRNPK protein CTD PMID:28073184 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997
JBrowse link
G Hnrnpul2 heterogeneous nuclear ribonucleoprotein U-like 2 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of HNRNPUL2 protein CTD PMID:28073184 NCBI chr 1:205,713,431...205,725,553
Ensembl chr 1:205,711,886...205,725,553
JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of HSDL2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of HSDL2 mRNA CTD PMID:30547786 NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839
JBrowse link
G Hspa12a heat shock protein family A (Hsp70) member 12A multiple interactions ISO [Palmitic Acid co-treated with Arsenic] affects the expression of HSPA12A mRNA CTD PMID:33736254 NCBI chr 1:257,935,642...258,096,602
Ensembl chr 1:257,935,644...258,096,846
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions
EXP
ISO
Palmitic Acid results in increased expression of HSPA5 mRNA
Palmitic Acid results in increased expression of HSPA5 protein
[Palmitic Acid co-treated with Oleic Acid] affects the expression of HSPA5 mRNA
obeticholic acid inhibits the reaction [Palmitic Acid results in increased expression of HSPA5 protein]; trigonelline inhibits the reaction [Palmitic Acid results in increased expression of HSPA5 protein]
CTD PMID:24349266 PMID:26655953 PMID:30208301 PMID:30547786 PMID:30738135 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A increases expression ISO Palmitic Acid results in increased expression of HTR2A protein CTD PMID:27133527 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B increases expression ISO Palmitic Acid results in increased expression of HTR2B protein CTD PMID:27133527 NCBI chr 9:86,735,793...86,756,640
Ensembl chr 9:86,742,102...86,755,108
JBrowse link
G Huwe1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of HUWE1 protein CTD PMID:28073184 NCBI chr  X:20,871,278...21,001,378
Ensembl chr  X:20,873,795...21,001,262
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression
multiple interactions
ISO Palmitic Acid results in increased expression of ICAM1 protein
geraniol inhibits the reaction [Palmitic Acid results in increased expression of ICAM1 protein]
CTD PMID:27107694 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifnb1 interferon beta 1 increases expression
multiple interactions
ISO Palmitic Acid results in increased expression of IFNB1 mRNA
amlexanox inhibits the reaction [Palmitic Acid results in increased expression of IFNB1 mRNA]; pitavastatin inhibits the reaction [Palmitic Acid results in increased expression of IFNB1 mRNA]; Pravastatin inhibits the reaction [Palmitic Acid results in increased expression of IFNB1 mRNA]
CTD PMID:18323514 PMID:32905826 NCBI chr 5:103,020,969...103,021,523
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Igf2 insulin-like growth factor 2 increases expression ISO Palmitic Acid results in increased expression of IGF2 mRNA CTD PMID:17658692 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon increases phosphorylation
multiple interactions
ISO Palmitic Acid results in increased phosphorylation of IKBKE protein
amlexanox inhibits the reaction [Palmitic Acid results in increased phosphorylation of IKBKE protein]
CTD PMID:32905826 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143
JBrowse link
G Il10 interleukin 10 affects expression
decreases expression
multiple interactions
ISO Palmitic Acid affects the expression of IL10 mRNA
Palmitic Acid results in decreased expression of IL10 protein
amlexanox affects the reaction [Palmitic Acid affects the expression of IL10 mRNA]; amlexanox inhibits the reaction [Palmitic Acid results in decreased expression of IL10 protein]; mifobate affects the reaction [Palmitic Acid affects the expression of IL10 mRNA]
CTD PMID:32905826 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [Palmitic Acid co-treated with Arsenic] results in increased expression of IL1A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of IL1A mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of IL1A mRNA CTD PMID:30547786 PMID:33736254 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
increases secretion
EXP
ISO
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein; [Palmitic Acid co-treated with Sincalide] results in increased expression of IL1B mRNA; [Palmitic Acid co-treated with Sincalide] results in increased expression of IL1B protein; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein]; Quercetin inhibits the reaction [[Sincalide co-treated with Palmitic Acid] results in increased expression of IL1B protein]
(R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of PPARG mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of PPARA mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CCL2 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CCL5 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CXCL5 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NFKB1 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of PPARD mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of RELA mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein; Bezafibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Bezafibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Bezafibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Bezafibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; GW 506033X inhibits the reaction [Palmitic Acid results in increased expression of IL1B mRNA]; GW 506033X inhibits the reaction [Palmitic Acid results in increased expression of IL1B protein]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]
Palmitic Acid results in increased expression of IL1B mRNA; Palmitic Acid results in increased expression of IL1B protein
Palmitic Acid results in increased secretion of IL1B protein
[Palmitic Acid co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL1B protein; amlexanox inhibits the reaction [Palmitic Acid results in increased expression of IL1B mRNA]; amlexanox inhibits the reaction [Palmitic Acid results in increased secretion of IL1B protein]; baicalin inhibits the reaction [Palmitic Acid results in increased secretion of IL1B protein]; CA 074 methyl ester inhibits the reaction [Palmitic Acid results in increased expression of IL1B protein]; NLRP3 inhibits the reaction [Palmitic Acid results in increased expression of IL1B protein]; Silymarin inhibits the reaction [[Palmitic Acid co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL1B protein]; ursodoxicoltaurine inhibits the reaction [Palmitic Acid results in increased secretion of IL1B protein]
CTD PMID:26190035 PMID:26873426 PMID:27689324 PMID:29031535 PMID:29753610 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 increases expression
affects expression
increases secretion
multiple interactions
ISO
EXP
Palmitic Acid results in increased expression of IL6 mRNA
Palmitic Acid affects the expression of IL6 mRNA
Palmitic Acid results in increased secretion of IL6 protein
3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]; [Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein; [Palmitic Acid co-treated with Sincalide] results in increased expression of IL6 mRNA; [Palmitic Acid co-treated with Sincalide] results in increased expression of IL6 protein; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]; AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; coomassie Brilliant Blue inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; coomassie Brilliant Blue inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; imoxin inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; Metformin inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; parthenolide inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [[Sincalide co-treated with Palmitic Acid] results in increased expression of IL6 protein]; Resveratrol inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; Resveratrol inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; Resveratrol inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; Salicylic Acid inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; SB 203580 inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; SB 203580 inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]
3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid results in increased secretion of IL6 protein]; [Palmitic Acid co-treated with Arsenic] affects the expression of IL6 mRNA; [Palmitic Acid co-treated with Thioacetamide] results in increased secretion of IL6 protein; tin protoporphyrin IX inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid results in increased secretion of IL6 protein]]
amlexanox inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; amlexanox inhibits the reaction [Palmitic Acid results in increased secretion of IL6 protein]; baicalin inhibits the reaction [Palmitic Acid results in increased secretion of IL6 protein]; pitavastatin inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; Pravastatin inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; ursodoxicoltaurine inhibits the reaction [Palmitic Acid results in increased secretion of IL6 protein]
CTD PMID:18323514 PMID:25108154 PMID:25348860 PMID:25815690 PMID:26873426 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins2 insulin 2 multiple interactions
decreases expression
ISO (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Rosiglitazone inhibits the reaction [Palmitic Acid results in decreased expression of INS protein]]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of NOS3 protein]]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]]; 4-phenylbutyric acid inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; 4-phenylbutyric acid inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of PPARG mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of PPARA mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CCL2 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CCL5 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CXCL5 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NFKB1 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of PPARD mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of RELA mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein; bafilomycin A1 promotes the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; Bezafibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Bezafibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Bezafibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Bezafibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; NCOA4 protein affects the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; NCOA4 protein inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of NOS3 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Rosiglitazone inhibits the reaction [Palmitic Acid results in decreased expression of INS protein]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Sirolimus inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; STF 083010 inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; STF 083010 inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; Thapsigargin inhibits the reaction [ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]]; Thapsigargin inhibits the reaction [NCOA4 protein inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]]; tin protoporphyrin IX inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]]]; tin protoporphyrin IX inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of NOS3 protein]]]; tin protoporphyrin IX inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]]]
[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of Palmitic Acid analog; [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased abundance of Palmitic Acid analog; Palmitic Acid inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]
CTD PMID:18155663 PMID:22558381 PMID:25815690 PMID:26820058 PMID:32283200 More... NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Insr insulin receptor multiple interactions ISO [Palmitic Acid co-treated with Arsenic] results in increased expression of INSR mRNA CTD PMID:33736254 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Irf3 interferon regulatory factor 3 increases phosphorylation
multiple interactions
ISO Palmitic Acid results in increased phosphorylation of IRF3 protein
amlexanox inhibits the reaction [Palmitic Acid results in increased phosphorylation of IRF3 protein]; pitavastatin inhibits the reaction [Palmitic Acid results in increased phosphorylation of IRF3 protein]; Pravastatin inhibits the reaction [Palmitic Acid results in increased phosphorylation of IRF3 protein]
CTD PMID:18323514 PMID:32905826 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
JBrowse link
G Irf4 interferon regulatory factor 4 increases expression ISO Palmitic Acid results in increased expression of IRF4 mRNA CTD PMID:32347412 NCBI chr17:33,721,800...33,742,570
Ensembl chr17:33,721,811...33,740,070
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]]; Palmitic Acid inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of IRS1 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]; tin protoporphyrin IX inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]]] CTD PMID:25815690 PMID:30362509 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions
decreases phosphorylation
ISO [GCG protein co-treated with candesartan] inhibits the reaction [Palmitic Acid results in decreased phosphorylation of IRS2 protein]; candesartan inhibits the reaction [Palmitic Acid results in decreased phosphorylation of IRS2 protein]; GCG protein inhibits the reaction [Palmitic Acid results in decreased phosphorylation of IRS2 protein]
[Palmitic Acid co-treated with Arsenic] results in increased expression of IRS2 mRNA
CTD PMID:21255808 PMID:33736254 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
JBrowse link
G Itprid2 ITPR interacting domain containing 2 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of ITPRID2 protein CTD PMID:28073184 NCBI chr 3:64,536,707...64,573,978
Ensembl chr 3:64,536,707...64,573,978
JBrowse link
G Itsn1 intersectin 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of ITSN1 protein CTD PMID:28073184 NCBI chr11:30,978,590...31,160,645
Ensembl chr11:30,978,590...31,160,645
JBrowse link
G Iyd iodotyrosine deiodinase multiple interactions ISO Palmitic Acid inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
JBrowse link
G Jak1 Janus kinase 1 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of JAK1 protein; [Palmitic Acid co-treated with Oleic Acid] affects the expression of JAK1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of JAK1 protein CTD PMID:30547786 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid] affects the expression of JAK2 mRNA CTD PMID:30547786 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Jmjd1c jumonji domain containing 1C increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of JMJD1C protein CTD PMID:28073184 NCBI chr20:21,332,147...21,494,220
Ensembl chr20:21,332,147...21,463,122
JBrowse link
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of JMJD6 protein CTD PMID:28073184 NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Palmitic Acid co-treated with Arsenic] results in increased expression of JUN mRNA CTD PMID:33736254 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kat7 lysine acetyltransferase 7 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of KAT7 protein CTD PMID:28073184 NCBI chr10:80,221,519...80,255,590
Ensembl chr10:80,221,524...80,255,567
JBrowse link
G Kctd12 potassium channel tetramerization domain containing 12 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of KCTD12 protein CTD PMID:28073184 NCBI chr15:79,800,077...79,806,064 JBrowse link
G Krt8 keratin 8 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of KRT8 protein CTD PMID:28073184 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Krt80 keratin 80 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of KRT80 protein CTD PMID:28073184 NCBI chr 7:132,464,807...132,485,026
Ensembl chr 7:132,463,218...132,485,508
JBrowse link
G Lamb1 laminin subunit beta 1 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of LAMB1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of LAMB1 mRNA CTD PMID:30547786 NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585
JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of LAMTOR1 protein CTD PMID:28073184 NCBI chr 1:156,272,116...156,277,687
Ensembl chr 1:156,272,064...156,291,179
JBrowse link
G Larp1 La ribonucleoprotein 1, translational regulator decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of LARP1 protein CTD PMID:28073184 NCBI chr10:42,191,378...42,246,361
Ensembl chr10:42,191,325...42,243,371
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of LDLR mRNA CTD PMID:30547786 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Leo1 LEO1 homolog, Paf1/RNA polymerase II complex component increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of LEO1 protein CTD PMID:28073184 NCBI chr 8:76,199,547...76,223,983
Ensembl chr 8:76,199,099...76,223,983
JBrowse link
G Lig1 DNA ligase 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of LIG1 protein CTD PMID:28073184 NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413
JBrowse link
G Lima1 LIM domain and actin binding 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of LIMA1 protein CTD PMID:28073184 NCBI chr 7:130,901,717...131,001,573
Ensembl chr 7:130,901,717...131,001,473
JBrowse link
G Limch1 LIM and calponin homology domains 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of LIMCH1 protein CTD PMID:28073184 NCBI chr14:41,112,579...41,425,185
Ensembl chr14:41,114,803...41,425,191
JBrowse link
G Lipc lipase C, hepatic type multiple interactions
decreases abundance
ISO [LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of Palmitic Acid
LIPC gene mutant form results in decreased abundance of Palmitic Acid
CTD PMID:24777581 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Lipg lipase G, endothelial type multiple interactions ISO [LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of Palmitic Acid CTD PMID:24777581 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
JBrowse link
G Lmo7 LIM domain 7 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of LMO7 protein CTD PMID:28073184 NCBI chr15:78,567,029...78,769,833
Ensembl chr15:78,567,023...78,769,783
JBrowse link
G Mafa MAF bZIP transcription factor A multiple interactions ISO Palmitic Acid inhibits the reaction [Glucose results in increased expression of MAFA mRNA] CTD PMID:22558381 NCBI chr 7:107,432,292...107,435,061
Ensembl chr 7:107,433,605...107,434,690
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta affects localization
increases expression
multiple interactions
ISO
EXP
Palmitic Acid affects the localization of MAP1LC3B protein
Palmitic Acid results in increased expression of MAP1LC3B protein modified form
C1QTNF9 protein promotes the reaction [Palmitic Acid results in increased expression of MAP1LC3B protein modified form]
[Palmitic Acid co-treated with Oleic Acid] affects the expression of MAP1LC3B mRNA
CTD PMID:30208301 PMID:30547786 PMID:32278738 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP3K8 mRNA CTD PMID:30547786 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216
JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP4K4 mRNA CTD PMID:30547786 NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
EXP
ISO
acetovanillone inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK1 protein]; CYBA mutant form inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK1 protein]
Quercetin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK1 protein]
Docosahexaenoic Acids inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK1 protein]
CTD PMID:24080574 PMID:24986865 PMID:25614714 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions
increases phosphorylation
ISO [Palmitic Acid co-treated with Arsenic] results in increased expression of MAPK14 mRNA; Capsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK14 protein] CTD PMID:21745629 PMID:33736254 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
EXP
ISO
acetovanillone inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK3 protein]; CYBA mutant form inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK3 protein]
Quercetin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK3 protein]
Docosahexaenoic Acids inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK3 protein]
CTD PMID:24080574 PMID:24986865 PMID:25614714 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases expression
increases phosphorylation
ISO
EXP
Capsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]
Palmitic Acid results in increased expression of MAPK8 mRNA
Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of MAPK8 mRNA]; imoxin inhibits the reaction [Palmitic Acid results in increased expression of and results in increased phosphorylation of MAPK8 protein]; imoxin inhibits the reaction [Palmitic Acid results in increased expression of MAPK8 mRNA]; Palmitic Acid results in increased expression of and results in increased phosphorylation of MAPK8 protein; parthenolide inhibits the reaction [Palmitic Acid results in increased expression of MAPK8 mRNA]; pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased expression of MAPK8 mRNA]; pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]
Chromium inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]
CTD PMID:21134603 PMID:21745629 PMID:30259999 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases phosphorylation
ISO Capsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK9 protein]
Chromium inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK9 protein]
CTD PMID:21134603 PMID:21745629 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of MARCKS protein CTD PMID:28073184 NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
JBrowse link
G Mdc1 mediator of DNA damage checkpoint 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of MDC1 protein CTD PMID:28073184 NCBI chr20:2,893,693...2,912,394
Ensembl chr20:2,895,505...2,910,240
JBrowse link
G Mdn1 midasin AAA ATPase 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of MDN1 protein CTD PMID:28073184 NCBI chr 5:47,055,435...47,190,426
Ensembl chr 5:47,055,447...47,186,332
JBrowse link
G Me1 malic enzyme 1 increases expression ISO Palmitic Acid results in increased expression of ME1 mRNA CTD PMID:29414781 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Med24 mediator complex subunit 24 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of MED24 protein CTD PMID:28073184 NCBI chr10:83,664,609...83,702,315
Ensembl chr10:83,664,609...83,690,123
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase multiple interactions ISO Palmitic Acid inhibits the reaction [Quercetin results in decreased expression of MET protein] CTD PMID:25971889 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link
G Mfap1a microfibrillar-associated protein 1A increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of MFAP1 protein CTD PMID:28073184 NCBI chr 3:108,440,163...108,456,744
Ensembl chr 3:108,438,845...108,456,750
JBrowse link
G Mff mitochondrial fission factor multiple interactions ISO 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of MFF mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of MFF mRNA CTD PMID:32369900 NCBI chr 9:84,007,798...84,036,039
Ensembl chr 9:84,007,798...84,036,039
JBrowse link
G Mfn1 mitofusin 1 multiple interactions ISO 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of MFN1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of MFN1 mRNA CTD PMID:32369900 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
JBrowse link
G Mfn2 mitofusin 2 multiple interactions ISO [Fructose co-treated with Palmitic Acid] results in decreased expression of MFN2 protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of MFN2 protein] CTD PMID:32730863 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mgat1 alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase multiple interactions
increases expression
ISO 7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased expression of MGAT1 mRNA] CTD PMID:29414781 NCBI chr10:33,563,642...33,582,718
Ensembl chr10:33,561,388...33,591,503
JBrowse link
G Mief1 mitochondrial elongation factor 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of MIEF1 protein CTD PMID:28073184 NCBI chr 7:111,786,630...111,802,220
Ensembl chr 7:111,786,709...111,802,220
JBrowse link
G Misp mitotic spindle positioning decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of MISP protein CTD PMID:28073184 NCBI chr 7:9,870,390...9,886,541
Ensembl chr 7:9,870,444...9,886,541
JBrowse link
G Mki67 marker of proliferation Ki-67 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of MKI67 protein CTD PMID:28073184 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MMP2 mRNA CTD PMID:26187275 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mpdz multiple PDZ domain crumbs cell polarity complex component increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of MPDZ protein CTD PMID:28073184 NCBI chr 5:95,766,112...95,920,531
Ensembl chr 5:95,766,118...95,920,499
JBrowse link
G Mrtfa myocardin related transcription factor A affects localization
multiple interactions
ISO Palmitic Acid affects the localization of MRTFA protein
CCG 1423 inhibits the reaction [Palmitic Acid affects the localization of MRTFA protein]
CTD PMID:21393865 NCBI chr 7:112,544,312...112,714,431
Ensembl chr 7:112,544,312...112,714,418
JBrowse link
G Msl3 MSL complex subunit 3 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of MSL3 protein CTD PMID:28073184 NCBI chr  X:25,638,029...25,655,698
Ensembl chr  X:25,637,804...25,655,697
JBrowse link
G Mt1 metallothionein 1 multiple interactions EXP [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of MT1 mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of MT1 mRNA; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of MT1 mRNA] CTD PMID:26854922 NCBI chr19:10,826,032...10,827,048 JBrowse link
G Mt2A metallothionein 2A decreases expression
multiple interactions
ISO
EXP
Palmitic Acid results in decreased expression of MT2A mRNA
[Palmitic Acid co-treated with Arsenic] results in increased expression of MT2A mRNA
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of MT2A mRNA
CTD PMID:17658692 PMID:26854922 PMID:33736254 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mta3 metastasis associated 1 family, member 3 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of MTA3 protein CTD PMID:28073184 NCBI chr 6:10,867,028...10,987,221
Ensembl chr 6:10,867,011...10,986,883
JBrowse link
G Mtbp MDM2 binding protein increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of MTBP protein CTD PMID:28073184 NCBI chr 7:86,973,069...87,055,775
Ensembl chr 7:86,973,069...87,050,827
JBrowse link
G Mtdh metadherin decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of MTDH protein CTD PMID:28073184 NCBI chr 7:65,306,464...65,365,647
Ensembl chr 7:65,306,400...65,364,413
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
increases phosphorylation
increases activity
ISO sarpogrelate inhibits the reaction [Palmitic Acid results in increased activity of MTOR protein]; Sirolimus inhibits the reaction [Palmitic Acid results in increased activity of MTOR protein]
trigonelline inhibits the reaction [Palmitic Acid results in increased phosphorylation of MTOR protein]
CTD PMID:27133527 PMID:30208301 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Mttp microsomal triglyceride transfer protein multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MTTP mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of MTTP mRNA CTD PMID:30547786 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 multiple interactions ISO [Palmitic Acid co-treated with Arsenic] affects the expression of NAIP mRNA CTD PMID:33736254 NCBI chr 2:31,507,423...31,559,098 JBrowse link
G Nbn nibrin decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of NBN protein CTD PMID:28073184 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150
JBrowse link
G Ncapd2 non-SMC condensin I complex, subunit D2 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of NCAPD2 protein CTD PMID:28073184 NCBI chr 4:157,968,814...157,992,314
Ensembl chr 4:157,968,815...157,992,020
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions
increases expression
EXP acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of NCF1 mRNA]; U 0126 inhibits the reaction [Palmitic Acid results in increased expression of NCF1 mRNA] CTD PMID:24080574 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 increases expression
multiple interactions
EXP Palmitic Acid results in increased expression of NCF2 mRNA
acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of NCF2 mRNA]; U 0126 inhibits the reaction [Palmitic Acid results in increased expression of NCF2 mRNA]
CTD PMID:24080574 NCBI chr13:64,955,502...64,986,289
Ensembl chr13:64,955,503...64,986,277
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of NCOA2 protein CTD PMID:28073184 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
JBrowse link
G Ncoa4 nuclear receptor coactivator 4 multiple interactions
increases expression
ISO Deferoxamine promotes the reaction [Palmitic Acid results in increased expression of NCOA4 protein]; ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased expression of NCOA4 protein]; NCOA4 protein affects the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; NCOA4 protein inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; Thapsigargin inhibits the reaction [NCOA4 protein inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]]; Wortmannin inhibits the reaction [Palmitic Acid results in increased expression of NCOA4 protein] CTD PMID:32283200 NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,366,542...7,409,641
Ensembl chr16:7,366,542...7,409,641
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of NCOR1 protein CTD PMID:28073184 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
JBrowse link
G Ndrg2 NDRG family member 2 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of NDRG2 protein CTD PMID:28073184 NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626
JBrowse link
G Nelfe negative elongation factor complex member E decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of NELFE protein CTD PMID:28073184 NCBI chr20:3,976,512...3,982,389
Ensembl chr20:3,976,518...3,982,355
JBrowse link
G Nexn nexilin (F actin binding protein) decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of NEXN protein CTD PMID:28073184 NCBI chr 2:241,186,783...241,218,315
Ensembl chr 2:241,186,790...241,218,342
JBrowse link
G Nf1 neurofibromin 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of NF1 protein CTD PMID:28073184 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NFE2L2 mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NFE2L2 mRNA]
[Fructose co-treated with Palmitic Acid] results in decreased expression of NFE2L2 protein; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of and affects the localization of NFE2L2 protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of NFE2L2 protein]; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of and affects the localization of NFE2L2 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein]
CTD PMID:26847930 PMID:32730863 PMID:32976958 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of NFIL3 protein CTD PMID:28073184 NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases expression
EXP
ISO
Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of NFKB1 mRNA]; imoxin inhibits the reaction [Palmitic Acid results in increased expression of NFKB1 mRNA]; parthenolide inhibits the reaction [Palmitic Acid results in increased expression of NFKB1 mRNA]; pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased expression of NFKB1 mRNA]
[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NFKB1 mRNA
CTD PMID:30259999 PMID:32613381 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha increases degradation
multiple interactions
decreases phosphorylation
ISO
EXP
Palmitic Acid results in increased degradation of NFKBIA protein
Quercetin inhibits the reaction [Palmitic Acid results in decreased phosphorylation of NFKBIA protein]
[Palmitic Acid co-treated with Sincalide] results in increased degradation of NFKBIA protein; Quercetin inhibits the reaction [[Sincalide co-treated with Palmitic Acid] results in increased degradation of NFKBIA protein]
CTD PMID:21687928 PMID:25614714 PMID:26873426 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions EXP [Palmitic Acid co-treated with Sincalide] results in increased degradation of NFKBIB protein; Quercetin inhibits the reaction [[Sincalide co-treated with Palmitic Acid] results in increased degradation of NFKBIB protein] CTD PMID:26873426 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions
increases expression
ISO
EXP
baicalin inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 protein]; NLRP3 inhibits the reaction [Palmitic Acid results in increased cleavage of CASP1 protein]; NLRP3 inhibits the reaction [Palmitic Acid results in increased expression of IL1B protein]; ursodoxicoltaurine inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 protein]
Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 mRNA]; imoxin inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 mRNA]; parthenolide inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 mRNA]; pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 mRNA]
CTD PMID:27689324 PMID:29031535 PMID:30259999 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nol8 nucleolar protein 8 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of NOL8 protein CTD PMID:28073184 NCBI chr17:14,990,394...15,013,784
Ensembl chr17:14,990,417...15,013,848
JBrowse link
G Nolc1 nucleolar and coiled-body phosphoprotein 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of NOLC1 protein CTD PMID:28073184 NCBI chr 1:244,921,275...244,932,089
Ensembl chr 1:244,921,377...244,932,088
JBrowse link
G Nop56 NOP56 ribonucleoprotein increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of NOP56 protein CTD PMID:28073184 NCBI chr 3:117,476,963...117,481,847
Ensembl chr 3:117,477,053...117,481,841
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions
ISO
EXP
Palmitic Acid results in increased expression of NOS2 mRNA
Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; imoxin inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; Metformin inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; parthenolide inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; Quercetin inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; Resveratrol inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; Salicylic Acid inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]
amlexanox inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; amlexanox inhibits the reaction [Palmitic Acid results in increased expression of NOS2 protein]; mifobate inhibits the reaction [amlexanox inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]]; pitavastatin inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; Pravastatin inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]
Palmitic Acid results in increased expression of NOS2 mRNA; Palmitic Acid results in increased expression of NOS2 protein
rosiglitazone inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]
CTD PMID:18155663 PMID:18323514 PMID:22713545 PMID:25108154 PMID:30259999 More... NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions EXP
ISO
AICA ribonucleotide inhibits the reaction [Palmitic Acid inhibits the reaction [Acetylcholine results in increased phosphorylation of NOS3 protein]]; Metformin inhibits the reaction [Palmitic Acid inhibits the reaction [Acetylcholine results in increased phosphorylation of NOS3 protein]]; Palmitic Acid inhibits the reaction [Acetylcholine results in increased phosphorylation of NOS3 protein]; Resveratrol inhibits the reaction [Palmitic Acid inhibits the reaction [Acetylcholine results in increased phosphorylation of NOS3 protein]]; Salicylic Acid inhibits the reaction [Palmitic Acid inhibits the reaction [Acetylcholine results in increased phosphorylation of NOS3 protein]]
3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of NOS3 protein]]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of NOS3 protein]; tin protoporphyrin IX inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of NOS3 protein]]]
CTD PMID:25108154 PMID:25815690 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nox1 NADPH oxidase 1 increases expression
multiple interactions
EXP
ISO
Palmitic Acid results in increased expression of NOX1 mRNA
geraniol inhibits the reaction [Palmitic Acid results in increased expression of NOX1 protein]
CTD PMID:24080574 PMID:27107694 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236
JBrowse link
G Noxa1 NADPH oxidase activator 1 multiple interactions
increases expression
EXP acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of NOXA1 mRNA]; U 0126 inhibits the reaction [Palmitic Acid results in increased expression of NOXA1 mRNA] CTD PMID:24080574 NCBI chr 3:7,895,488...7,907,011
Ensembl chr 3:7,895,488...7,905,967
JBrowse link
G Noxo1 NADPH oxidase organizer 1 multiple interactions
increases expression
EXP acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of NOXO1 mRNA]; U 0126 inhibits the reaction [Palmitic Acid results in increased expression of NOXO1 mRNA] CTD PMID:24080574 NCBI chr10:13,721,473...13,726,061
Ensembl chr10:13,721,473...13,726,061
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [Palmitic Acid co-treated with Arsenic] results in increased expression of NQO1 mRNA CTD PMID:33736254 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 decreases expression
multiple interactions
ISO Palmitic Acid results in decreased expression of NR1H2 mRNA; Palmitic Acid results in decreased expression of NR1H2 protein
acanthoic acid inhibits the reaction [Palmitic Acid results in decreased expression of NR1H2 mRNA]; acanthoic acid inhibits the reaction [Palmitic Acid results in decreased expression of NR1H2 protein]; GW 3965 inhibits the reaction [Palmitic Acid results in decreased expression of NR1H2 mRNA]; GW 3965 inhibits the reaction [Palmitic Acid results in decreased expression of NR1H2 protein]; pregna-4,17-diene-3,16-dione promotes the reaction [Palmitic Acid results in decreased expression of NR1H2 mRNA]
CTD PMID:31421115 NCBI chr 1:95,041,967...95,047,377
Ensembl chr 1:95,041,967...95,047,377
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions
decreases expression
EXP
ISO
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of NR1H3 mRNA
acanthoic acid inhibits the reaction [Palmitic Acid results in decreased expression of NR1H3 mRNA]; acanthoic acid inhibits the reaction [Palmitic Acid results in decreased expression of NR1H3 protein]; GW 3965 inhibits the reaction [Palmitic Acid results in decreased expression of NR1H3 mRNA]; GW 3965 inhibits the reaction [Palmitic Acid results in decreased expression of NR1H3 protein]
Palmitic Acid results in decreased expression of NR1H3 mRNA; Palmitic Acid results in decreased expression of NR1H3 protein
CTD PMID:26190035 PMID:31421115 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions
decreases expression
increases expression
ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of NR1H4 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of NR1H4 mRNA; Permethrin inhibits the reaction [Palmitic Acid results in increased expression of NR1H4 mRNA]
Palmitic Acid results in decreased expression of NR1H4 mRNA; Palmitic Acid results in decreased expression of NR1H4 protein
acanthoic acid inhibits the reaction [Palmitic Acid results in decreased expression of NR1H4 mRNA]; acanthoic acid inhibits the reaction [Palmitic Acid results in decreased expression of NR1H4 protein]; GW 3965 inhibits the reaction [Palmitic Acid results in decreased expression of NR1H4 mRNA]; GW 3965 inhibits the reaction [Palmitic Acid results in decreased expression of NR1H4 protein]; pregna-4,17-diene-3,16-dione promotes the reaction [Palmitic Acid results in decreased expression of NR1H4 mRNA]
CTD PMID:30547786 PMID:30738135 PMID:31421115 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of NR3C1 protein CTD PMID:28073184 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nrf1 nuclear respiratory factor 1 multiple interactions ISO [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA] CTD PMID:26847930 NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
JBrowse link
G Ntsr1 neurotensin receptor 1 increases expression ISO Palmitic Acid results in increased expression of NTSR1 mRNA CTD PMID:32347412 NCBI chr 3:167,606,215...167,656,377
Ensembl chr 3:167,606,215...167,656,377
JBrowse link
G Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of NUCKS1 protein CTD PMID:28073184 NCBI chr13:43,345,091...43,374,316
Ensembl chr13:43,345,115...43,370,229
JBrowse link
G Nup153 nucleoporin 153 affects phosphorylation ISO Palmitic Acid affects the phosphorylation of NUP153 protein CTD PMID:28073184 NCBI chr17:17,972,217...18,024,876
Ensembl chr17:17,972,217...18,024,876
JBrowse link
G Nup50 nucleoporin 50 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of NUP50 protein CTD PMID:28073184 NCBI chr 7:116,047,960...116,065,231
Ensembl chr 7:116,048,021...116,066,905
JBrowse link
G Obi1 ORC ubiquitin ligase 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of OBI1 protein CTD PMID:28073184 NCBI chr15:81,269,413...81,308,734
Ensembl chr15:81,269,416...81,308,734
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions ISO [Fructose co-treated with Palmitic Acid] results in decreased expression of OPA1 protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of OPA1 protein] CTD PMID:32730863 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Osbp oxysterol binding protein decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of OSBP protein CTD PMID:28073184 NCBI chr 1:208,888,697...208,918,511
Ensembl chr 1:208,887,895...208,918,506
JBrowse link
G Oxr1 oxidation resistance 1 decreases phosphorylation
multiple interactions
ISO Palmitic Acid results in decreased phosphorylation of OXR1 protein
[Palmitic Acid co-treated with Arsenic] results in increased expression of OXR1 mRNA
CTD PMID:28073184 PMID:33736254 NCBI chr 7:72,528,782...72,965,666
Ensembl chr 7:72,528,786...72,965,666
JBrowse link
G Oxsr1 oxidative stress responsive kinase 1 multiple interactions ISO [Palmitic Acid co-treated with Arsenic] results in increased expression of OXSR1 mRNA CTD PMID:33736254 NCBI chr 8:118,972,754...119,062,102
Ensembl chr 8:118,972,754...119,062,027
JBrowse link
G P2rx7 purinergic receptor P2X 7 multiple interactions EXP [Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 protein; Resveratrol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 mRNA]; Resveratrol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 protein] CTD PMID:25348860 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of PAICS protein CTD PMID:28073184 NCBI chr14:31,199,086...31,232,731
Ensembl chr14:31,173,541...31,232,635
JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of PAK2 protein CTD PMID:28073184 NCBI chr11:68,708,070...68,766,622
Ensembl chr11:68,707,969...68,768,816
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases expression
increases cleavage
ISO
EXP
trigonelline inhibits the reaction [Palmitic Acid results in increased cleavage of PARP1 protein]
Palmitic Acid results in increased expression of PARP1 mRNA; Palmitic Acid results in increased expression of PARP1 protein
CTD PMID:19513971 PMID:30208301 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]] CTD PMID:26847930 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pcnp PEST proteolytic signal containing nuclear protein decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of PCNP protein CTD PMID:28073184 NCBI chr11:44,592,766...44,607,372
Ensembl chr11:44,592,742...44,607,348
JBrowse link
G Pcnt pericentrin decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of PCNT protein CTD PMID:28073184 NCBI chr20:12,190,597...12,278,723
Ensembl chr20:12,191,648...12,278,710
JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions ISO 3-(4-chlorophenyl)-N-methyl-N'-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboxamidine analog inhibits the reaction [[osteum co-treated with Palmitic Acid] results in increased expression of PDGFA mRNA]; [osteum co-treated with Palmitic Acid] results in increased expression of PDGFA mRNA CTD PMID:31454063 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 multiple interactions
increases expression
ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PDK4 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PDK4 protein
Palmitic Acid results in increased expression of PDK4 mRNA
CTD PMID:30547786 PMID:32347412 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 decreases expression
multiple interactions
ISO
EXP
Palmitic Acid results in decreased expression of PDX1 mRNA
3-aminobenzamide inhibits the reaction [Palmitic Acid results in decreased expression of PDX1 protein]; geniposide inhibits the reaction [Palmitic Acid results in decreased expression of PDX1 protein]
Palmitic Acid inhibits the reaction [Glucose affects the localization of PDX1 protein]
Palmitic Acid inhibits the reaction [Glucose results in increased expression of PDX1 mRNA]
CTD PMID:18155663 PMID:19513971 PMID:22558381 PMID:22819839 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PEBP1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PEBP1 mRNA CTD PMID:30547786 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
JBrowse link
G Pex1 peroxisomal biogenesis factor 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of PEX1 protein CTD PMID:28073184 NCBI chr 4:30,519,950...30,558,953
Ensembl chr 4:30,519,955...30,558,921
JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha increases abundance ISO PEX11A gene mutant form results in increased abundance of Palmitic Acid CTD PMID:30585412 NCBI chr 1:133,680,091...133,687,172
Ensembl chr 1:133,680,091...133,687,172
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of PFKFB3 protein CTD PMID:28073184 NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125
JBrowse link
G Phldb2 pleckstrin homology-like domain, family B, member 2 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of PHLDB2 protein CTD PMID:28073184 NCBI chr11:54,859,173...55,078,212
Ensembl chr11:54,859,135...55,078,467
JBrowse link
G Piezo1 piezo-type mechanosensitive ion channel component 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of PIEZO1 protein CTD PMID:28073184 NCBI chr19:50,544,580...50,606,812
Ensembl chr19:50,544,582...50,606,501
JBrowse link
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid] affects the expression of PIK3C2A mRNA CTD PMID:30547786 NCBI chr 1:170,577,942...170,684,353
Ensembl chr 1:170,577,942...170,683,472
JBrowse link
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of PIKFYVE protein CTD PMID:28073184 NCBI chr 9:66,563,747...66,657,873
Ensembl chr 9:66,563,727...66,657,868
JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions ISO 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of PINK1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of PINK1 mRNA CTD PMID:32369900 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Pklr pyruvate kinase L/R multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PKLR mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PKLR mRNA CTD PMID:30547786 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
JBrowse link
G Pld1 phospholipase D1 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PLD1 mRNA CTD PMID:30547786 NCBI chr 2:110,849,205...111,047,692
Ensembl chr 2:110,893,608...111,047,692
JBrowse link
G Plec plectin decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of PLEC protein CTD PMID:28073184 NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467
JBrowse link
G Plin1 perilipin 1 multiple interactions
increases expression
ISO trigonelline inhibits the reaction [Palmitic Acid results in increased expression of PLIN1 protein] CTD PMID:30208301 NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
JBrowse link
G Plin2 perilipin 2 multiple interactions ISO
EXP
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PLIN2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PLIN2 protein
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN2 mRNA
CTD PMID:25048947 PMID:30547786 NCBI chr 5:101,156,643...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Plin3 perilipin 3 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PLIN3 mRNA CTD PMID:30547786 NCBI chr 9:1,111,178...1,123,117 JBrowse link
G Plin5 perilipin 5 multiple interactions EXP [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN5 mRNA; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN5 mRNA] CTD PMID:25048947 NCBI chr 9:939,745...946,188
Ensembl chr 9:939,747...946,120
JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of PNKP protein CTD PMID:28073184 NCBI chr 1:95,341,465...95,346,921
Ensembl chr 1:95,341,620...95,346,920
JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PNPLA3 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PNPLA3 mRNA CTD PMID:30547786 NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077
JBrowse link
G Pof1b POF1B, actin binding protein decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of POF1B protein CTD PMID:28073184 NCBI chr  X:77,683,128...77,749,827
Ensembl chr  X:77,683,128...77,749,688
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
decreases expression
increases expression
affects abundance
increases activity
ISO
EXP
[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of PPARA mRNA; [Palmitic Acid co-treated with Arsenic] results in increased expression of PPARA mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PPARA mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PPARA mRNA; Ivermectin inhibits the reaction [Palmitic Acid results in increased expression of PPARA mRNA]; Palmitic Acid binds to and results in increased activity of PPARA protein; Permethrin inhibits the reaction [Palmitic Acid results in increased expression of PPARA mRNA]
Palmitic Acid results in decreased expression of PPARA mRNA; Palmitic Acid results in decreased expression of PPARA protein
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARA mRNA; [tetrabromobisphenol A co-treated with Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; [Triiodothyronine co-treated with Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein]
PPARA protein affects the abundance of Palmitic Acid
amlexanox inhibits the reaction [Palmitic Acid results in decreased expression of PPARA mRNA]; amlexanox inhibits the reaction [Palmitic Acid results in decreased expression of PPARA protein]; amlexanox promotes the reaction [Palmitic Acid results in increased expression of PPARA protein]; Diethylhexyl Phthalate inhibits the reaction [PPARA protein affects the abundance of Palmitic Acid]; Palmitic Acid inhibits the reaction [obeticholic acid results in increased expression of PPARA mRNA]; PPARA protein promotes the reaction [[GW 7647 results in increased oxidation of Palmitic Acid] which results in increased abundance of Carbon Dioxide]; PPARA protein promotes the reaction [[GW 7647 results in increased oxidation of Palmitic Acid] which results in increased abundance of Fatty Acids metabolite]
Palmitic Acid results in increased activity of PPARA protein
Palmitic Acid results in increased expression of PPARA mRNA; Palmitic Acid results in increased expression of PPARA protein
CTD PMID:10403814 PMID:18154422 PMID:21324916 PMID:23619606 PMID:25048947 More... NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta multiple interactions EXP
ISO
[Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased expression of PPARD mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARB mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARD mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARB mRNA]; tetrabromobisphenol A inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARD mRNA]
[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of PPARD mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PPARD mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PPARD mRNA
CTD PMID:25048947 PMID:26190035 PMID:26854922 PMID:30547786 PMID:32613381 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
multiple interactions
decreases expression
ISO
EXP
Palmitic Acid results in increased expression of PPARG mRNA; Palmitic Acid results in increased expression of PPARG protein
trigonelline inhibits the reaction [Palmitic Acid results in increased expression of PPARG protein]
[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of PPARG mRNA; ATG7 protein affects the reaction [trigonelline inhibits the reaction [Palmitic Acid results in increased expression of PPARG protein]]; trigonelline inhibits the reaction [Palmitic Acid results in increased expression of PPARG protein]
[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of PPARG mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA; AICA ribonucleotide inhibits the reaction [Palmitic Acid results in decreased expression of PPARG mRNA]; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA]; Metformin inhibits the reaction [Palmitic Acid results in decreased expression of PPARG mRNA]; Resveratrol inhibits the reaction [Palmitic Acid results in decreased expression of PPARG mRNA]; Salicylic Acid inhibits the reaction [Palmitic Acid results in decreased expression of PPARG mRNA]; tetrabromobisphenol A inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA]; Triiodothyronine inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA]
CTD PMID:18154422 PMID:25048947 PMID:25108154 PMID:26190035 PMID:26854922 More... NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression
multiple interactions
EXP
ISO
Palmitic Acid results in increased expression of PPARGC1A mRNA
[Fructose co-treated with Palmitic Acid] results in decreased expression of PPARGC1A protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of PPARGC1A protein]
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA]
CTD PMID:23056435 PMID:26847930 PMID:32730863 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of PPP1R12A protein CTD PMID:28073184 NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425
JBrowse link
G Ppp1r2 protein phosphatase 1, regulatory (inhibitor) subunit 2 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of PPP1R2 protein CTD PMID:28073184 NCBI chr11:69,472,676...69,494,468
Ensembl chr11:69,472,555...69,494,463
JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions ISO [Palmitic Acid co-treated with Arsenic] results in increased expression of PRDX1 mRNA CTD PMID:33736254 NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions
increases oxidation
ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PRKAA1 mRNA
PRKAA1 protein results in increased oxidation of Palmitic Acid
CTD PMID:30547786 PMID:31040181 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid] affects the expression of PRKAA2 mRNA CTD PMID:30547786 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
JBrowse link
G Prkcd protein kinase C, delta decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of PRKCD protein CTD PMID:28073184 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Prkce protein kinase C, epsilon increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of PRKCE protein CTD PMID:28073184 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Prkd3 protein kinase D3 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of PRKD3 protein CTD PMID:28073184 NCBI chr 6:16,032,507...16,108,444
Ensembl chr 6:16,032,585...16,108,443
JBrowse link
G Proser2 proline and serine rich 2 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of PROSER2 protein CTD PMID:28073184 NCBI chr17:72,151,961...72,187,524
Ensembl chr17:72,151,872...72,185,825
JBrowse link
G Prpf40a pre-mRNA processing factor 40 homolog A increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of PRPF40A protein CTD PMID:28073184 NCBI chr 3:37,625,585...37,689,859
Ensembl chr 3:37,627,690...37,690,886
JBrowse link
G Prrc2b proline-rich coiled-coil 2B affects phosphorylation ISO Palmitic Acid affects the phosphorylation of PRRC2B protein CTD PMID:28073184 NCBI chr 3:15,433,357...15,519,105
Ensembl chr 3:15,465,294...15,519,104
JBrowse link
G Psmc3ip PSMC3 interacting protein increases expression ISO Palmitic Acid results in increased expression of PSMC3IP mRNA CTD PMID:17658692 NCBI chr10:86,024,281...86,027,928
Ensembl chr10:86,023,950...86,027,423
JBrowse link
G Ptges3 prostaglandin E synthase 3 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of PTGES3 protein CTD PMID:28073184 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 increases expression ISO Palmitic Acid results in increased expression of PTPN1 protein CTD PMID:22509299 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
JBrowse link
G Ptx3 pentraxin 3 increases expression ISO Palmitic Acid results in increased expression of PTX3 mRNA CTD PMID:32347412 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323
JBrowse link
G Pycard PYD and CARD domain containing affects localization ISO Palmitic Acid affects the localization of PYCARD protein CTD PMID:27689324 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Rab18 RAB18, member RAS oncogene family multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RAB18 mRNA CTD PMID:30547786 NCBI chr17:54,944,099...54,976,093
Ensembl chr17:54,943,955...54,976,043
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of RACGAP1 protein CTD PMID:28073184 NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
JBrowse link
G Rad18 RAD18 E3 ubiquitin protein ligase increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of RAD18 protein CTD PMID:28073184 NCBI chr 4:145,735,654...145,821,102
Ensembl chr 4:145,735,654...145,821,069
JBrowse link
G Ralbp1 ralA binding protein 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of RALBP1 protein CTD PMID:28073184 NCBI chr 9:105,456,425...105,492,711
Ensembl chr 9:105,456,425...105,492,707
JBrowse link
G Ralgapa2 Ral GTPase activating protein catalytic subunit alpha 2 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of RALGAPA2 protein CTD PMID:28073184 NCBI chr 3:133,661,955...133,938,821
Ensembl chr 3:133,659,761...133,938,916
JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of RAPGEF2 protein CTD PMID:28073184 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247
JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of RB1CC1 protein CTD PMID:28073184 NCBI chr 5:13,161,648...13,225,560
Ensembl chr 5:13,161,648...13,225,560
JBrowse link
G Rbm15 RNA binding motif protein 15 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of RBM15 protein CTD PMID:28073184 NCBI chr 2:194,945,717...194,954,523
Ensembl chr 2:194,945,974...194,954,703
JBrowse link
G Rbm34 RNA binding motif protein 34 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of RBM34 protein CTD PMID:28073184 NCBI chr19:54,936,516...54,956,810
Ensembl chr19:54,936,531...54,956,715
JBrowse link
G Rcc1 regulator of chromosome condensation 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of RCC1 protein CTD PMID:28073184 NCBI chr 5:144,526,025...144,544,445
Ensembl chr 5:144,526,025...144,544,577
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases phosphorylation
multiple interactions
ISO
EXP
Palmitic Acid results in increased phosphorylation of RELA protein
3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid results in increased phosphorylation of and results in increased activity of RELA protein]; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of RELA mRNA; cyanidin-3-O-beta-glucopyranoside inhibits the reaction [Palmitic Acid affects the localization of and results in increased activity of RELA protein]; Palmitic Acid affects the localization of and results in increased activity of RELA protein; Palmitic Acid results in increased phosphorylation of and results in increased activity of RELA protein; tin protoporphyrin IX inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid results in increased phosphorylation of and results in increased activity of RELA protein]]; wedelolactone inhibits the reaction [Palmitic Acid affects the localization of and results in increased activity of RELA protein]
AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]; dorsomorphin inhibits the reaction [AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]]; dorsomorphin inhibits the reaction [Metformin inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]]; dorsomorphin inhibits the reaction [Resveratrol inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]]; dorsomorphin inhibits the reaction [Salicylic Acid inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]]; Metformin inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]; Niacinamide inhibits the reaction [AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]]; Niacinamide inhibits the reaction [Metformin inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]]; Niacinamide inhibits the reaction [Resveratrol inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]]; Niacinamide inhibits the reaction [Salicylic Acid inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]]; Resveratrol inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]; Salicylic Acid inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]
CTD PMID:21745629 PMID:25108154 PMID:25815690 PMID:26422990 PMID:32613381 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Repin1 replication initiator 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of REPIN1 protein CTD PMID:28073184 NCBI chr 4:77,548,722...77,554,242
Ensembl chr 4:77,548,849...77,554,257
JBrowse link
G RGD1310553 similar to expressed sequence AI597479 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of C2ORF49 protein CTD PMID:28073184 NCBI chr 9:45,371,396...45,382,123
Ensembl chr 9:45,371,430...45,382,120
JBrowse link
G RGD1564664 similar to LOC387763 protein increases expression ISO Palmitic Acid results in increased expression of C11ORF96 mRNA CTD PMID:32347412 NCBI chr 3:79,920,131...79,921,523
Ensembl chr 3:79,920,129...79,921,523
JBrowse link
G Rheb Ras homolog, mTORC1 binding multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHEB mRNA CTD PMID:30547786 NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160
JBrowse link
G Rhob ras homolog family member B multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHOB mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of RHOB mRNA CTD PMID:30547786 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
JBrowse link
G Rnasel ribonuclease L increases expression ISO Palmitic Acid results in increased expression of RNASEL protein CTD PMID:24651439 NCBI chr13:65,894,990...65,910,354
Ensembl chr13:65,901,459...65,908,704
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ROCK2 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ROCK2 protein CTD PMID:30547786 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031
JBrowse link
G Rprd2 regulation of nuclear pre-mRNA domain containing 2 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of RPRD2 protein CTD PMID:28073184 NCBI chr 2:183,311,132...183,367,959
Ensembl chr 2:183,293,114...183,367,407
JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of RPS6 protein CTD PMID:28073184 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of RPS6KB1 protein CTD PMID:28073184 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Rrbp1 ribosome binding protein 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of RRBP1 protein CTD PMID:28073184 NCBI chr 3:131,314,996...131,376,930
Ensembl chr 3:131,314,998...131,376,981
JBrowse link
G Rrp1b ribosomal RNA processing 1B increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of RRP1B protein CTD PMID:28073184 NCBI chr20:10,123,111...10,148,704
Ensembl chr20:10,123,125...10,147,928
JBrowse link
G Rrp9 ribosomal RNA processing 9, U3 small nucleolar RNA binding protein increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of RRP9 protein CTD PMID:28073184 NCBI chr 8:107,116,411...107,126,123
Ensembl chr 8:107,117,471...107,126,123
JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression
multiple interactions
EXP Palmitic Acid results in increased expression of RUNX2 mRNA
acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of RUNX2 mRNA]; CYBA mutant form inhibits the reaction [Palmitic Acid results in increased expression of RUNX2 mRNA]; U 0126 inhibits the reaction [Palmitic Acid results in increased expression of RUNX2 mRNA]
CTD PMID:24080574 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Sbsn suprabasin increases expression ISO Palmitic Acid results in increased expression of SBSN mRNA CTD PMID:32347412 NCBI chr 1:85,979,477...86,006,034
Ensembl chr 1:86,001,567...86,006,034
JBrowse link
G Scaf1 SR-related CTD-associated factor 1 affects phosphorylation ISO Palmitic Acid affects the phosphorylation of SCAF1 protein CTD PMID:28073184 NCBI chr 1:95,485,448...95,499,389
Ensembl chr 1:95,485,448...95,496,029
JBrowse link
G Scd stearoyl-CoA desaturase increases expression
multiple interactions
decreases response to substance
EXP
ISO
Palmitic Acid results in increased expression of SCD1 mRNA
acanthoic acid inhibits the reaction [Palmitic Acid results in increased expression of SCD1 mRNA]; GW 3965 inhibits the reaction [Palmitic Acid results in increased expression of SCD1 mRNA]; pregna-4,17-diene-3,16-dione inhibits the reaction [Palmitic Acid results in increased expression of SCD1 mRNA]
(R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SCD mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SCD mRNA; Bezafibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]
Palmitic Acid results in increased expression of SCD1 mRNA; Palmitic Acid results in increased expression of SCD1 protein
SCD1 protein results in decreased susceptibility to Palmitic Acid
SCD1 protein inhibits the reaction [Palmitic Acid results in increased abundance of Ceramides]; SCD1 protein inhibits the reaction [Palmitic Acid results in increased abundance of Reactive Oxygen Species]; SCD1 protein inhibits the reaction [Palmitic Acid results in increased activity of CASP3 protein]
CTD PMID:22413010 PMID:29414781 PMID:30547786 PMID:31421115 PMID:32613381 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Sec22b SEC22 homolog B, vesicle trafficking protein decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of SEC22B protein CTD PMID:28073184 NCBI chr 2:185,500,029...185,520,811
Ensembl chr 2:185,500,004...185,522,026
JBrowse link
G Sele selectin E increases expression
multiple interactions
ISO Palmitic Acid results in increased expression of SELE mRNA
cyanidin-3-O-beta-glucopyranoside inhibits the reaction [Palmitic Acid results in increased expression of SELE mRNA]; wedelolactone inhibits the reaction [Palmitic Acid results in increased expression of SELE mRNA]
CTD PMID:26422990 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Septin9 septin 9 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of SEPTIN9 protein CTD PMID:28073184 NCBI chr10:102,409,798...102,579,056
Ensembl chr10:102,409,711...102,579,055
JBrowse link
G Serpine1 serpin family E member 1 increases expression
multiple interactions
ISO Palmitic Acid results in increased expression of SERPINE1 mRNA
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SERPINE1 mRNA
CTD PMID:17658692 PMID:30547786 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sf3b2 splicing factor 3b, subunit 2 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of SF3B2 protein CTD PMID:28073184 NCBI chr 1:202,570,423...202,590,774
Ensembl chr 1:202,570,423...202,590,759
JBrowse link
G Shroom3 shroom family member 3 affects phosphorylation ISO Palmitic Acid affects the phosphorylation of SHROOM3 protein CTD PMID:28073184 NCBI chr14:15,099,415...15,396,832
Ensembl chr14:15,099,423...15,396,915
JBrowse link
G Sirt1 sirtuin 1 decreases expression
decreases activity
multiple interactions
EXP
ISO
Palmitic Acid results in decreased expression of SIRT1 mRNA; Palmitic Acid results in decreased expression of SIRT1 protein
Palmitic Acid results in decreased activity of SIRT1 protein
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [Palmitic Acid results in decreased activity of SIRT1 protein]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide promotes the reaction [Palmitic Acid results in decreased activity of SIRT1 protein]; [Fructose co-treated with Palmitic Acid] results in decreased expression of SIRT1 protein; [Palmitic Acid co-treated with Glucose] promotes the reaction [Glutathione binds to SIRT1 protein]; [Palmitic Acid co-treated with Glucose] results in increased oxidation of and results in decreased activity of SIRT1 protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of SIRT1 protein]; GLRX protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] promotes the reaction [Glutathione binds to SIRT1 protein]]; GLRX protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased oxidation of and results in decreased activity of SIRT1 protein]; Resveratrol inhibits the reaction [Palmitic Acid results in decreased activity of SIRT1 protein]; SIRT1 protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased acetylation of TP53 protein]; SIRT1 protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased cleavage of CASP3 protein]; SIRT1 protein inhibits the reaction [Palmitic Acid results in decreased activity of SIRT1 protein]; SIRT1 protein mutant form inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased expression of BBC3 mRNA]; SIRT1 protein mutant form inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased expression of CDKN1A mRNA]; SIRT1 protein promotes the reaction [Resveratrol inhibits the reaction [Palmitic Acid results in decreased activity of SIRT1 protein]]
[Ethanol co-treated with Oleic Acid co-treated with Palmitic Acid] results in decreased expression of SIRT1 protein; resveratrol inhibits the reaction [Palmitic Acid results in decreased expression of SIRT1 mRNA]
CTD PMID:22968147 PMID:24451382 PMID:25108154 PMID:25943029 PMID:26854922 More... NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Sirt3 sirtuin 3 decreases expression ISO Palmitic Acid results in decreased expression of SIRT3 protein CTD PMID:30958623 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808
JBrowse link
G Slc1a3 solute carrier family 1 member 3 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of SLC1A3 protein CTD PMID:28073184 NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605
JBrowse link
G Slc23a2 solute carrier family 23 member 2 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of SLC23A2 protein CTD PMID:28073184 NCBI chr 3:119,302,651...119,395,289
Ensembl chr 3:119,302,666...119,460,343
JBrowse link
G Slc25a20 solute carrier family 25 member 20 increases expression EXP Palmitic Acid results in increased expression of SLC25A20 mRNA; Palmitic Acid results in increased expression of SLC25A20 protein CTD PMID:24349266 NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SLC2A1 mRNA CTD PMID:30547786 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Slc2a2 solute carrier family 2 member 2 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of SLC2A2 mRNA CTD PMID:30547786 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Slc2a4 solute carrier family 2 member 4 decreases expression
multiple interactions
EXP
ISO
Palmitic Acid results in decreased expression of SLC2A4 protein
[Palmitic Acid co-treated with Arsenic] affects the expression of SLC2A4 mRNA
Quercetin inhibits the reaction [Palmitic Acid results in decreased expression of SLC2A4 protein]
CTD PMID:22713545 PMID:28073184 PMID:33736254 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc38a2 solute carrier family 38, member 2 multiple interactions
affects expression
ISO [Palmitic Acid co-treated with Arsenic] affects the expression of SLC38A2 mRNA
Palmitic Acid affects the expression of SLC38A2 mRNA
CTD PMID:33736254 NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436
JBrowse link
G Slc4a1ap solute carrier family 4 member 1 adaptor protein decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of SLC4A1AP protein CTD PMID:28073184 NCBI chr 6:24,905,941...24,933,651
Ensembl chr 6:24,905,941...24,933,815
JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of SMARCA4 protein CTD PMID:28073184 NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975
JBrowse link
G Smg1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of SMG1 protein CTD PMID:28073184 NCBI chr 1:172,441,892...172,543,667
Ensembl chr 1:172,444,936...172,543,698
JBrowse link
G Smim20 small integral membrane protein 20 multiple interactions ISO Palmitic Acid inhibits the reaction [SMIM20 protein results in increased phosphorylation of CREB1 protein] CTD PMID:30716364 NCBI chr14:57,711,304...57,722,681 JBrowse link
G Snap23 synaptosome associated protein 23 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SNAP23 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SNAP23 mRNA CTD PMID:30547786 NCBI chr 3:107,514,088...107,546,177 JBrowse link
G Snapin SNAP-associated protein increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of SNAPIN protein CTD PMID:28073184 NCBI chr 2:175,971,575...175,974,164
Ensembl chr 2:175,971,257...175,974,231
JBrowse link
G Socs1 suppressor of cytokine signaling 1 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOCS1 mRNA CTD PMID:30547786 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link
G Socs2 suppressor of cytokine signaling 2 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SOCS2 mRNA CTD PMID:30547786 NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions
affects expression
ISO [Palmitic Acid co-treated with Arsenic] affects the expression of SOCS3 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS3 mRNA
Palmitic Acid affects the expression of SOCS3 mRNA
CTD PMID:30547786 PMID:33736254 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Sod1 superoxide dismutase 1 decreases expression
multiple interactions
ISO
EXP
Palmitic Acid results in decreased expression of SOD1 mRNA
[Glucose co-treated with Palmitic Acid] results in decreased expression of SOD1 protein
rosiglitazone inhibits the reaction [Palmitic Acid results in decreased expression of SOD1 mRNA]
CTD PMID:18155663 PMID:28027979 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 increases expression
multiple interactions
decreases expression
EXP
ISO
Palmitic Acid results in increased expression of SOD2 mRNA
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOD2 mRNA
Palmitic Acid results in decreased expression of SOD2 mRNA; Palmitic Acid results in decreased expression of SOD2 protein
CTD PMID:24349266 PMID:28027979 PMID:30547786 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Son SON DNA and RNA binding protein decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of SON protein CTD PMID:28073184 NCBI chr11:30,850,890...30,923,167
Ensembl chr11:30,892,005...30,923,167
JBrowse link
G Sort1 sortilin 1 multiple interactions
increases degradation
increases phosphorylation
ISO Cycloheximide promotes the reaction [Palmitic Acid results in increased degradation of SORT1 protein]; Docosahexaenoic Acids inhibits the reaction [Cycloheximide promotes the reaction [Palmitic Acid results in increased degradation of SORT1 protein]]; Docosahexaenoic Acids inhibits the reaction [Palmitic Acid results in decreased expression of SORT1 protein]; Eicosapentaenoic Acid inhibits the reaction [Palmitic Acid results in decreased expression of SORT1 protein]
Palmitic Acid results in increased phosphorylation of SORT1 protein
CTD PMID:24986865 NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354
JBrowse link
G Sowahc sosondowah ankyrin repeat domain family member C increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of SOWAHC protein CTD PMID:28073184 NCBI chr20:27,195,198...27,199,664 JBrowse link
G Spag1 sperm associated antigen 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of SPAG1 protein CTD PMID:28073184 NCBI chr 7:67,361,474...67,421,369
Ensembl chr 7:67,361,477...67,421,368
JBrowse link
G Spag7 sperm associated antigen 7 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of SPAG7 protein CTD PMID:28073184 NCBI chr10:55,377,249...55,383,404
Ensembl chr10:55,377,249...55,383,404
JBrowse link
G Spast spastin decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of SPAST protein CTD PMID:28073184 NCBI chr 6:21,055,349...21,106,586
Ensembl chr 6:21,055,349...21,107,954
JBrowse link
G Specc1 sperm antigen with calponin homology and coiled-coil domains 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of SPECC1 protein CTD PMID:28073184 NCBI chr10:46,638,947...46,912,989
Ensembl chr10:46,638,809...46,912,802
JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions
ISO
EXP
Palmitic Acid results in increased expression of SQSTM1 protein
Deferoxamine promotes the reaction [Palmitic Acid results in increased expression of SQSTM1 protein]; Palmitic Acid inhibits the reaction [Arsenic Trioxide results in decreased expression of SQSTM1 protein]; trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SQSTM1 protein]
CTD PMID:30208301 PMID:30362509 PMID:32278738 PMID:32283200 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions
increases expression
ISO
EXP
ATG5 protein promotes the reaction [Resveratrol inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]]; ATG7 protein affects the reaction [trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]]; BECN1 protein promotes the reaction [Resveratrol inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]]; Resveratrol inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]; trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]
acanthoic acid inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 mRNA]; acanthoic acid inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]; amlexanox inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 mRNA]; GW 3965 inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 mRNA]; GW 3965 inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]; trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]
Palmitic Acid results in increased expression of SREBF1 mRNA; Palmitic Acid results in increased expression of SREBF1 protein; Palmitic Acid results in increased expression of SREBF1 protein modified form
[Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased expression of SREBF1 protein; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA]
CTD PMID:25943029 PMID:26190035 PMID:26854922 PMID:29414781 PMID:30208301 More... NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srrm1 serine and arginine repetitive matrix 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of SRRM1 protein CTD PMID:28073184 NCBI chr 5:147,559,515...147,591,895
Ensembl chr 5:147,559,514...147,591,849
JBrowse link
G Srrm2 serine/arginine repetitive matrix 2 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of SRRM2 protein CTD PMID:28073184 NCBI chr10:12,815,471...12,848,750
Ensembl chr10:12,815,471...12,848,751
JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of STAT3 protein CTD PMID:28073184 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stk11 serine/threonine kinase 11 multiple interactions
decreases phosphorylation
ISO 5-methyltetrahydrofolate inhibits the reaction [Palmitic Acid results in decreased phosphorylation of STK11 protein]; dorsomorphin inhibits the reaction [5-methyltetrahydrofolate inhibits the reaction [Palmitic Acid results in decreased phosphorylation of STK11 protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [5-methyltetrahydrofolate inhibits the reaction [Palmitic Acid results in decreased phosphorylation of STK11 protein]] CTD PMID:26400185 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
JBrowse link
G Sugt1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of SUGT1 protein CTD PMID:28073184 NCBI chr15:54,991,419...55,032,244
Ensembl chr15:54,990,672...55,069,150
JBrowse link
G Synrg synergin, gamma increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of SYNRG protein CTD PMID:28073184 NCBI chr10:68,848,828...68,931,252 JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member multiple interactions ISO [Palmitic Acid co-treated with Arsenic] affects the expression of TAP1 mRNA CTD PMID:33736254 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901
JBrowse link
G Tbc1d1 TBC1 domain family member 1 multiple interactions ISO TBC1D1 protein results in decreased uptake of and results in decreased oxidation of Palmitic Acid CTD PMID:18931681 NCBI chr14:43,936,820...44,135,133
Ensembl chr14:43,935,636...44,136,499
JBrowse link
G Tbc1d4 TBC1 domain family, member 4 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of TBC1D4 protein CTD PMID:28073184 NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265
JBrowse link
G Tbc1d5 TBC1 domain family, member 5 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of TBC1D5 protein CTD PMID:28073184 NCBI chr 9:3,503,328...4,017,131
Ensembl chr 9:3,513,623...4,016,913
JBrowse link
G Tbk1 TANK-binding kinase 1 multiple interactions
increases phosphorylation
ISO amlexanox inhibits the reaction [Palmitic Acid results in increased phosphorylation of TBK1 protein] CTD PMID:32905826 NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892
JBrowse link
G Tcof1 treacle ribosome biogenesis factor 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of TCOF1 protein CTD PMID:28073184 NCBI chr18:54,267,015...54,300,324
Ensembl chr18:54,267,026...54,300,324
JBrowse link
G Tfam transcription factor A, mitochondrial multiple interactions ISO [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of TFAM mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of TFAM mRNA] CTD PMID:26847930 NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
JBrowse link
G Tfap2c transcription factor AP-2 gamma increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of TFAP2C protein CTD PMID:28073184 NCBI chr 3:161,315,114...161,322,998
Ensembl chr 3:161,315,031...161,322,995
JBrowse link
G Tfpt TCF3 fusion partner decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of TFPT protein CTD PMID:28073184 NCBI chr 1:65,587,855...65,597,407
Ensembl chr 1:65,582,359...65,611,689
JBrowse link
G Tfrc transferrin receptor multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid] results in increased expression of TFRC protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of TFRC protein] CTD PMID:32976958 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases secretion
multiple interactions
ISO Palmitic Acid results in increased secretion of TGFB1 protein
[Palmitic Acid co-treated with Thioacetamide] results in increased secretion of TGFB1 protein
CTD PMID:30625377 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TGFB2 mRNA CTD PMID:30547786 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO [Oleic Acid co-treated with Palmitic Acid] results in increased expression of TIMP1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of TIMP1 mRNA CTD PMID:26187275 PMID:30547786 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tjp1 tight junction protein 1 decreases expression
multiple interactions
ISO Palmitic Acid results in decreased expression of TJP1 protein
[Palmitic Acid co-treated with Arsenic] affects the expression of TJP1 mRNA
CA 074 methyl ester inhibits the reaction [Palmitic Acid results in decreased expression of TJP1 protein]; Glycyrrhizic Acid inhibits the reaction [Palmitic Acid results in decreased expression of TJP1 protein]; L 709049 analog inhibits the reaction [Palmitic Acid results in decreased expression of TJP1 protein]
CTD PMID:27689324 PMID:33736254 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tjp2 tight junction protein 2 multiple interactions
decreases expression
ISO CA 074 methyl ester inhibits the reaction [Palmitic Acid results in decreased expression of TJP2 protein]; Glycyrrhizic Acid inhibits the reaction [Palmitic Acid results in decreased expression of TJP2 protein]; L 709049 analog inhibits the reaction [Palmitic Acid results in decreased expression of TJP2 protein] CTD PMID:27689324 NCBI chr 1:221,709,745...221,838,383
Ensembl chr 1:221,709,745...221,838,295
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions
increases expression
ISO Quercetin inhibits the reaction [Palmitic Acid results in increased expression of TLR4 mRNA] CTD PMID:25614714 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases secretion
increases expression
increases response to substance
ISO
EXP
(R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid results in increased secretion of TNF protein]; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of PPARG mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of PPARA mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CCL2 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CCL5 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CXCL5 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NFKB1 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of PPARD mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of RELA mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ABCA1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ACSL1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT5 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AHR mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ARG1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of B4GALT5 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CAT mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CXCL2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CXCL3 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1H1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1I1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ENO3 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ERLIN1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of FOXA1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of GLUD1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of GLUD2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of HSDL2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of IL1A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of LAMB1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of NR1H4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PEBP1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PKLR mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PLD1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PNPLA3 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PPARD mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PRKAA1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RAB18 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHEB mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHOB mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SCD mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SERPINE1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SLC2A1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOCS1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOD2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TGFB2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TNFAIP2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TUBB2A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of UGCG mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of VAMP4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of VCAN mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of CPT1A protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of DST mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ACSL4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANGPTL4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANXA2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CIDEC protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CPT1A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CXCL8 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP24A1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP26A1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FGF21 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FLOT1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HIF1A protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HILPDA protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of JAK1 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of LDLR mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP3K8 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP4K4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MTTP mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PPARA mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ROCK2 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SNAP23 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS3 mRNA; [Palmitic Acid co-treated with Thioacetamide] results in increased secretion of TNF protein; Bezafibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Bezafibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Bezafibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Bezafibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Palmitic Acid inhibits the reaction [TNF protein results in increased phosphorylation of AKT1 protein]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; tin protoporphyrin IX inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid results in increased secretion of TNF protein]]
Palmitic Acid results in increased expression of TNF protein
Palmitic Acid results in increased expression of TNF mRNA
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein; [Palmitic Acid co-treated with Sincalide] results in increased expression of TNF mRNA; [Palmitic Acid co-treated with Sincalide] results in increased expression of TNF protein; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]; AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]; imoxin inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]; Metformin inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]; parthenolide inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]; pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]; Quercetin inhibits the reaction [[Sincalide co-treated with Palmitic Acid] results in increased expression of TNF protein]; Quercetin inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]; Resveratrol inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]; Salicylic Acid inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]
amlexanox inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]; amlexanox inhibits the reaction [Palmitic Acid results in increased secretion of TNF protein]; Quercetin inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]; Quercetin inhibits the reaction [Palmitic Acid results in increased expression of TNF protein]
Palmitic Acid results in increased expression of TNF mRNA; Palmitic Acid results in increased expression of TNF protein
Palmitic Acid results in increased susceptibility to TNF protein
CTD PMID:18323514 PMID:22683933 PMID:22713545 PMID:25108154 PMID:25614714 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip2 TNF alpha induced protein 2 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TNFAIP2 mRNA CTD PMID:30547786 NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914
JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression
multiple interactions
ISO Palmitic Acid results in increased expression of TNFRSF9 mRNA
Quercetin inhibits the reaction [Palmitic Acid results in increased expression of TNFRSF9 mRNA]
CTD PMID:25614714 NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000
JBrowse link
G Tnks1bp1 tankyrase 1 binding protein 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of TNKS1BP1 protein CTD PMID:28073184 NCBI chr 3:70,135,335...70,160,071
Ensembl chr 3:70,137,837...70,160,038
JBrowse link
G Tns1 tensin 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of TNS1 protein CTD PMID:28073184 NCBI chr 9:75,491,886...75,702,853
Ensembl chr 9:75,495,814...75,703,225
JBrowse link
G Top2a DNA topoisomerase II alpha affects phosphorylation ISO Palmitic Acid affects the phosphorylation of TOP2A protein CTD PMID:28073184 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Tor1aip2 torsin 1A interacting protein 2 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of TOR1AIP2 protein CTD PMID:28073184 NCBI chr13:68,225,226...68,256,536
Ensembl chr13:68,230,009...68,256,536
Ensembl chr13:68,230,009...68,256,536
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of TP53 mRNA]; [Palmitic Acid co-treated with Glucose] results in increased acetylation of TP53 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of TP53 mRNA; SIRT1 protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased acetylation of TP53 protein] CTD PMID:24451382 PMID:32369900 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 affects phosphorylation ISO Palmitic Acid affects the phosphorylation of TP53BP1 protein CTD PMID:28073184 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822
JBrowse link
G Tp53bp2 tumor protein p53 binding protein, 2 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of TP53BP2 protein CTD PMID:28073184 NCBI chr13:94,088,769...94,145,436
Ensembl chr13:94,088,709...94,145,432
JBrowse link
G Tpd52l2 TPD52 like 2 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of TPD52L2 protein CTD PMID:28073184 NCBI chr 3:168,598,449...168,618,201 JBrowse link
G Trim63 tripartite motif containing 63 increases expression
multiple interactions
ISO Palmitic Acid results in increased expression of TRIM63 mRNA; Palmitic Acid results in increased expression of TRIM63 protein
Quercetin inhibits the reaction [Palmitic Acid results in increased expression of TRIM63 mRNA]; Quercetin inhibits the reaction [Palmitic Acid results in increased expression of TRIM63 protein]
CTD PMID:25614714 NCBI chr 5:146,533,492...146,547,332
Ensembl chr 5:146,533,507...146,547,322
JBrowse link
G Tubb2a tubulin, beta 2A class IIa multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TUBB2A mRNA CTD PMID:30547786 NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
JBrowse link
G Tufm Tu translation elongation factor, mitochondrial multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid] affects the expression of TUFM mRNA CTD PMID:30547786 NCBI chr 1:181,073,788...181,077,395
Ensembl chr 1:181,073,788...181,077,395
JBrowse link
G Txnip thioredoxin interacting protein increases expression
multiple interactions
ISO Palmitic Acid results in increased expression of TXNIP protein
AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of TXNIP protein]; baicalin inhibits the reaction [Palmitic Acid results in increased expression of TXNIP protein]; dorsomorphin inhibits the reaction [baicalin inhibits the reaction [Palmitic Acid results in increased expression of TXNIP protein]]
CTD PMID:29031535 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Ubr4 ubiquitin protein ligase E3 component n-recognin 4 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of UBR4 protein CTD PMID:28073184 NCBI chr 5:151,635,825...151,743,931
Ensembl chr 5:151,635,868...151,743,784
JBrowse link
G Ucp1 uncoupling protein 1 increases expression EXP Palmitic Acid results in increased expression of UCP1 mRNA CTD PMID:28027979 NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852
JBrowse link
G Ucp2 uncoupling protein 2 increases activity
multiple interactions
increases expression
ISO
EXP
Palmitic Acid results in increased activity of UCP2 protein
[Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in decreased expression of UCP2 protein; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of UCP2 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 protein; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 mRNA]; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 protein]; Triiodothyronine promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 mRNA]; Triiodothyronine promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 protein]
Palmitic Acid results in increased expression of UCP2 mRNA
candesartan inhibits the reaction [Palmitic Acid results in increased expression of UCP2 mRNA]
CTD PMID:12858170 PMID:20667613 PMID:25048947 PMID:26854922 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of UGCG mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of UGCG mRNA CTD PMID:30547786 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
JBrowse link
G Uri1 URI1, prefoldin-like chaperone increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of URI1 protein CTD PMID:28073184 NCBI chr 1:90,646,392...90,704,811
Ensembl chr 1:90,646,393...90,709,026
JBrowse link
G Usp1 ubiquitin specific peptidase 1 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of USP1 protein CTD PMID:28073184 NCBI chr 5:113,587,564...113,598,934
Ensembl chr 5:113,587,564...113,598,932
JBrowse link
G Utp14a UTP14A small subunit processome component decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of UTP14A protein CTD PMID:28073184 NCBI chr  X:127,439,282...127,464,634
Ensembl chr  X:127,439,268...127,464,633
JBrowse link
G Vamp4 vesicle-associated membrane protein 4 multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of VAMP4 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of VAMP4 mRNA CTD PMID:30547786 NCBI chr13:74,919,872...74,942,791
Ensembl chr13:74,919,880...74,933,686
JBrowse link
G Vapa VAMP associated protein A multiple interactions ISO [Palmitic Acid co-treated with Arsenic] affects the expression of VAPA mRNA CTD PMID:33736254 NCBI chr 9:105,177,904...105,208,400
Ensembl chr 9:105,177,907...105,207,847
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression
multiple interactions
ISO Palmitic Acid results in increased expression of VCAM1 mRNA; Palmitic Acid results in increased expression of VCAM1 protein
cyanidin-3-O-beta-glucopyranoside inhibits the reaction [Palmitic Acid results in increased expression of VCAM1 mRNA]; geraniol inhibits the reaction [Palmitic Acid results in increased expression of VCAM1 protein]; wedelolactone inhibits the reaction [Palmitic Acid results in increased expression of VCAM1 mRNA]
CTD PMID:26422990 PMID:27107694 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vcan versican multiple interactions ISO [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of VCAN mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of VCAN mRNA CTD PMID:30547786 NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637
JBrowse link
G Wrnip1 WRN helicase interacting protein 1 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of WRNIP1 protein CTD PMID:28073184 NCBI chr17:31,621,410...31,641,659
Ensembl chr17:31,621,411...31,641,659
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions
increases expression
EXP
ISO
[Palmitic Acid co-treated with Sincalide] results in increased expression of XBP1 mRNA alternative form; [Palmitic Acid co-treated with Sincalide] results in increased expression of XBP1 protein alternative form; Quercetin inhibits the reaction [[Sincalide co-treated with Palmitic Acid] results in increased expression of XBP1 protein alternative form]
Palmitic Acid results in increased expression of XBP1 protein
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased splicing of XBP1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased splicing of XBP1 mRNA; Deferoxamine promotes the reaction [Palmitic Acid results in increased expression of XBP1 protein]; ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased expression of XBP1 protein]
Palmitic Acid results in increased expression of XBP1 mRNA alternative form
7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased expression of XBP1 mRNA alternative form]; ATP2A2 protein promotes the reaction [7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased expression of XBP1 mRNA alternative form]]; Thapsigargin inhibits the reaction [7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased expression of XBP1 mRNA alternative form]]
CTD PMID:26873426 PMID:29414781 PMID:32283200 PMID:32369900 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Zfp609 zinc finger protein 609 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of ZNF609 protein CTD PMID:28073184 NCBI chr 8:66,214,553...66,349,319
Ensembl chr 8:66,214,555...66,317,977
JBrowse link
G Zfp687 zinc finger protein 687 increases phosphorylation ISO Palmitic Acid results in increased phosphorylation of ZNF687 protein CTD PMID:28073184 NCBI chr 2:182,572,893...182,581,641
Ensembl chr 2:182,572,662...182,583,647
JBrowse link
G Zfyve16 zinc finger FYVE-type containing 16 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of ZFYVE16 protein CTD PMID:28073184 NCBI chr 2:23,713,018...23,757,576
Ensembl chr 2:23,713,766...23,756,990
JBrowse link
G Zfyve19 zinc finger FYVE-type containing 19 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of ZFYVE19 protein CTD PMID:28073184 NCBI chr 3:106,195,779...106,203,969
Ensembl chr 3:106,195,899...106,203,969
JBrowse link
G Zranb2 zinc finger RANBP2-type containing 2 decreases phosphorylation ISO Palmitic Acid results in decreased phosphorylation of ZRANB2 protein CTD PMID:28073184 NCBI chr 2:246,573,110...246,586,942
Ensembl chr 2:246,573,166...246,586,942
JBrowse link
1,2-dihexadecanoyl-sn-glycero-3-phosphocholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 multiple interactions ISO 1,2-Dipalmitoylphosphatidylcholine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein] CTD PMID:19041333 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Prnp prion protein multiple interactions
affects folding
ISO Copper affects the reaction [1,2-Dipalmitoylphosphatidylcholine affects the folding of PRNP protein modified form] CTD PMID:20936829 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
JBrowse link
1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fech ferrochelatase affects abundance ISO FECH protein affects the abundance of 1-palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine CTD PMID:29906468 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
JBrowse link
1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lipg lipase G, endothelial type increases hydrolysis ISO LIPG protein results in increased hydrolysis of 1-O-hexadecyl-2-arachidonyl-sn-glycero-3-phosphocholine CTD PMID:15953354 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
JBrowse link
1-palmitoyl-2-oleoyl-sn-glycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lipc lipase C, hepatic type decreases abundance ISO LIPC gene mutant form results in decreased abundance of 1-palmitoyl-2-oleoyl-sn-glycerol CTD PMID:24777581 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Lipg lipase G, endothelial type decreases abundance ISO LIPG gene mutant form results in decreased abundance of 1-palmitoyl-2-oleoyl-sn-glycerol CTD PMID:24777581 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
JBrowse link
2-bromohexadecanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 decreases expression EXP 2-bromopalmitate results in decreased expression of APOA1 mRNA CTD PMID:7556148 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of CEBPB mRNA] CTD PMID:30076181 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO 2-bromopalmitate results in decreased expression of FAS mRNA CTD PMID:16712844 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases activity EXP 2-bromopalmitate results in increased activity of GAPDH protein CTD PMID:10650946 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of IFIT3 mRNA] CTD PMID:30076181 NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of IRF1 mRNA] CTD PMID:30076181 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Lat2 linker for activation of T cells family, member 2 decreases expression ISO 2-bromopalmitate results in decreased expression of LAT2 protein CTD PMID:23001822 NCBI chr12:22,104,163...22,118,294
Ensembl chr12:22,104,219...22,118,288
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO 2-bromopalmitate results in increased expression of LDLR mRNA CTD PMID:23150725 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lrat lecithin retinol acyltransferase increases expression EXP 2-bromopalmitate results in increased expression of LRAT mRNA CTD PMID:12576510 NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619
JBrowse link
G Ly6e lymphocyte antigen 6 family member E multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of LY6E mRNA] CTD PMID:30076181 NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in decreased expression of MPO mRNA] CTD PMID:30076181 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases activity
multiple interactions
ISO 2-bromopalmitate results in increased activity of PPARD protein
2-bromopalmitate results in increased activity of [RXRA protein binds to PPARD protein]
CTD PMID:15997096 PMID:21543282 PMID:23150725 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression EXP 2-bromopalmitate results in increased expression of PPARG protein CTD PMID:10650946 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions ISO 2-bromopalmitate binds to and results in increased expression of RARA protein; 2-bromopalmitate inhibits the reaction [Am 580 results in decreased expression of RARA protein]; 2-bromopalmitate inhibits the reaction [Tretinoin results in decreased expression of RARA protein]; [2-bromopalmitate results in increased susceptibility to Tretinoin] which results in increased expression of RARA protein CTD PMID:30076181 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rarb retinoic acid receptor, beta multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of RARB mRNA] CTD PMID:30076181 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
JBrowse link
G Rbp1 retinol binding protein 1 increases expression EXP 2-bromopalmitate results in increased expression of RBP1 mRNA CTD PMID:12576510 NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO 2-bromopalmitate results in increased activity of [RXRA protein binds to PPARD protein] CTD PMID:15997096 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Spi1 Spi-1 proto-oncogene multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of SPI1 mRNA] CTD PMID:30076181 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393
JBrowse link
G Tgm2 transglutaminase 2 multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of TGM2 mRNA] CTD PMID:30076181 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
JBrowse link
G Ucp2 uncoupling protein 2 increases expression EXP 2-bromopalmitate results in increased expression of UCP2 mRNA CTD PMID:11341955 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
2-hydroxyphytanic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rxra retinoid X receptor alpha affects binding ISO 2-hydroxyphytanic acid binds to RXRA protein CTD PMID:23843199 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Rxrb retinoid X receptor beta affects binding ISO 2-hydroxyphytanic acid binds to RXRB protein CTD PMID:23843199 NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773
JBrowse link
G Rxrg retinoid X receptor gamma affects binding ISO 2-hydroxyphytanic acid binds to RXRG protein CTD PMID:23843199 NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167
JBrowse link
all-trans-retinyl palmitate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase increases activity EXP retinol palmitate results in increased activity of CAT protein CTD PMID:20679000 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions EXP retinol palmitate promotes the reaction [EP300 protein binds to MMP9 protein] CTD PMID:17164434 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Il10 interleukin 10 multiple interactions ISO retinol palmitate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL10 protein] CTD PMID:17377406 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions ISO retinol palmitate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1RN protein] CTD PMID:17377406 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Lipe lipase E, hormone sensitive type increases hydrolysis
multiple interactions
ISO LIPE protein results in increased hydrolysis of retinol palmitate
PLIN3 protein inhibits the reaction [LIPE protein results in increased hydrolysis of retinol palmitate]
CTD PMID:16741517 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
EXP retinol palmitate promotes the reaction [EP300 protein binds to MMP9 protein]; retinol palmitate promotes the reaction [RARA protein binds to MMP9 protein]
retinol palmitate results in increased expression of MMP9 mRNA
CTD PMID:17164434 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Plin3 perilipin 3 multiple interactions ISO PLIN3 protein inhibits the reaction [LIPE protein results in increased hydrolysis of retinol palmitate]; PLIN3 protein inhibits the reaction [PNPLA4 protein results in increased hydrolysis of retinol palmitate] CTD PMID:16741517 NCBI chr 9:1,111,178...1,123,117 JBrowse link
G Pnpla4 patatin like phospholipase domain containing 4 increases hydrolysis
multiple interactions
ISO PNPLA4 protein results in increased hydrolysis of retinol palmitate
PLIN3 protein inhibits the reaction [PNPLA4 protein results in increased hydrolysis of retinol palmitate]
CTD PMID:16741517 NCBI chr  X:42,313,554...42,318,451
Ensembl chr  X:42,305,373...42,318,552
JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions EXP retinol palmitate promotes the reaction [RARA protein binds to MMP9 protein] CTD PMID:17164434 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression EXP retinol palmitate results in increased expression of SCARB1 mRNA CTD PMID:17299104 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
chloramphenicol palmitate term browser
Symbol Object Name Qualifiers Evidence Notes