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G |
Abca1 |
ATP binding cassette subfamily A member 1 |
multiple interactions decreases expression |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ABCA1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ABCA1 mRNA Palmitic Acid results in decreased expression of ABCA1 mRNA; Palmitic Acid results in decreased expression of ABCA1 protein morroniside inhibits the reaction [Palmitic Acid results in decreased expression of ABCA1 mRNA]; morroniside inhibits the reaction [Palmitic Acid results in decreased expression of ABCA1 protein] |
CTD |
PMID:30547786 PMID:34485530 |
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NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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G |
Abca2 |
ATP binding cassette subfamily A member 2 |
affects expression |
ISO |
Palmitic Acid affects the expression of ABCA2 mRNA |
CTD |
PMID:33736254 |
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NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
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G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] affects the expression of ABCC1 mRNA |
CTD |
PMID:33736254 |
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NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] results in increased expression of ABCC2 mRNA |
CTD |
PMID:33736254 |
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NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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G |
Abcc5 |
ATP binding cassette subfamily C member 5 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of ABCC5 protein |
CTD |
PMID:28073184 |
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NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
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G |
Abce1 |
ATP binding cassette subfamily E member 1 |
increases expression |
ISO |
Palmitic Acid results in increased expression of ABCE1 protein |
CTD |
PMID:24651439 |
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NCBI chr19:28,205,566...28,230,489
Ensembl chr19:28,205,555...28,230,489
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G |
Abcf1 |
ATP binding cassette subfamily F member 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of ABCF1 protein |
CTD |
PMID:28073184 |
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NCBI chr20:2,802,519...2,815,433
Ensembl chr20:2,802,488...2,815,433
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
increases expression multiple interactions decreases expression |
ISO |
Palmitic Acid results in increased expression of ABCG1 mRNA morroniside inhibits the reaction [Palmitic Acid results in decreased expression of ABCG1 mRNA]; morroniside inhibits the reaction [Palmitic Acid results in decreased expression of ABCG1 protein] Palmitic Acid results in decreased expression of ABCG1 mRNA; Palmitic Acid results in decreased expression of ABCG1 protein |
CTD |
PMID:16730733 PMID:34485530 |
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NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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G |
Acaca |
acetyl-CoA carboxylase alpha |
decreases phosphorylation increases expression multiple interactions |
ISO |
Palmitic Acid results in decreased phosphorylation of ACACA protein Palmitic Acid results in increased expression of ACACA mRNA amlexanox inhibits the reaction [Palmitic Acid results in increased expression of ACACA mRNA] [Fructose co-treated with Palmitic Acid] results in decreased expression of ACACA protein modified form; [Fructose co-treated with Palmitic Acid] results in increased expression of ACACA protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of ACACA protein modified form]; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of ACACA protein]; Ivermectin inhibits the reaction [Palmitic Acid results in decreased phosphorylation of ACACA protein] |
CTD |
PMID:30738135 PMID:32730863 PMID:32905826 |
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NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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G |
Acadm |
acyl-CoA dehydrogenase medium chain |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA] |
CTD |
PMID:26190035 |
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NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
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G |
Acadsb |
acyl-CoA dehydrogenase, short/branched chain |
multiple interactions |
ISO |
2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA]; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA] |
CTD |
PMID:32613381 |
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NCBI chr 1:186,188,939...186,227,796
Ensembl chr 1:186,188,987...186,230,379
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G |
Acin1 |
apoptotic chromatin condensation inducer 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of ACIN1 protein |
CTD |
PMID:28073184 |
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NCBI chr15:28,102,112...28,147,001
Ensembl chr15:28,102,112...28,147,001
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G |
Ackr3 |
atypical chemokine receptor 3 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] affects the expression of ACKR3 mRNA |
CTD |
PMID:33736254 |
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NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237
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G |
Acly |
ATP citrate lyase |
multiple interactions increases expression |
ISO |
acanthoic acid inhibits the reaction [Palmitic Acid results in increased expression of ACLY mRNA]; GW 3965 inhibits the reaction [Palmitic Acid results in increased expression of ACLY mRNA]; pregna-4,17-diene-3,16-dione inhibits the reaction [Palmitic Acid results in increased expression of ACLY mRNA] |
CTD |
PMID:31421115 |
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NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
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G |
Acsl1 |
acyl-CoA synthetase long-chain family member 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ACSL1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ACSL1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
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G |
Acsl4 |
acyl-CoA synthetase long-chain family member 4 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ACSL4 mRNA |
CTD |
PMID:30547786 |
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NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427
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G |
Acsl5 |
acyl-CoA synthetase long-chain family member 5 |
multiple interactions increases expression affects response to substance |
ISO |
[ACSL5 protein affects the susceptibility to Palmitic Acid] which affects the abundance of Adenosine Triphosphate Palmitic Acid results in increased expression of ACSL5 mRNA |
CTD |
PMID:32347412 |
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NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
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G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of ACTA2 mRNA |
CTD |
PMID:26187275 |
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Add1 |
adducin 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of ADD1 protein |
CTD |
PMID:28073184 |
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NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182
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G |
Adgre1 |
adhesion G protein-coupled receptor E1 |
increases expression multiple interactions |
ISO |
Palmitic Acid results in increased expression of ADGRE1 mRNA amlexanox inhibits the reaction [Palmitic Acid results in increased expression of ADGRE1 mRNA] |
CTD |
PMID:32905826 |
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NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
decreases expression increases expression multiple interactions |
EXP ISO |
Palmitic Acid results in decreased expression of ADIPOQ mRNA Palmitic Acid results in increased expression of ADIPOQ protein [Palmitic Acid co-treated with sodium arsenite] results in decreased expression of ADIPOQ mRNA; [Palmitic Acid co-treated with sodium arsenite] results in decreased expression of and results in decreased secretion of ADIPOQ protein; [sodium arsenite co-treated with Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of ADIPOQ mRNA; [sodium arsenite co-treated with Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of ADIPOQ protein; Palmitic Acid inhibits the reaction [[sodium arsenite co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased secretion of ADIPOQ protein]; sodium arsenite inhibits the reaction [Palmitic Acid results in increased expression of ADIPOQ protein] [osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOQ mRNA; [osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOQ protein; MRI-1867 inhibits the reaction [[osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOQ mRNA]; MRI-1867 inhibits the reaction [[osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOQ protein] AICA ribonucleotide inhibits the reaction [Palmitic Acid results in decreased expression of ADIPOQ mRNA]; Metformin inhibits the reaction [Palmitic Acid results in decreased expression of ADIPOQ mRNA]; Resveratrol inhibits the reaction [Palmitic Acid results in decreased expression of ADIPOQ mRNA]; Salicylic Acid inhibits the reaction [Palmitic Acid results in decreased expression of ADIPOQ mRNA] |
CTD |
PMID:25108154 PMID:31454063 PMID:34968464 |
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Adipor1 |
adiponectin receptor 1 |
multiple interactions |
ISO |
[osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOR1 protein; MRI-1867 inhibits the reaction [[osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOR1 protein] |
CTD |
PMID:31454063 |
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NCBI chr13:45,859,461...45,879,248
Ensembl chr13:45,859,533...45,879,241
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G |
Adipor2 |
adiponectin receptor 2 |
decreases expression multiple interactions increases expression |
ISO EXP |
palmitic acid decreases expression of ADIPOR2 mRNA and protein in hepatocellular carcinoma cells [osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOR2 protein; MRI-1867 inhibits the reaction [[osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOR2 protein] palmitic acid cotreated with ethanol increases expression of adipor2 mRNA in rat primary hepatocytes |
CTD RGD |
PMID:31454063 PMID:29569260 PMID:21194380 |
RGD:24922201, RGD:24922202 |
NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
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G |
Adnp |
activity-dependent neuroprotector homeobox |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of ADNP protein |
CTD |
PMID:28073184 |
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NCBI chr 3:156,886,921...156,921,500
Ensembl chr 3:156,891,381...156,917,312
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G |
Aebp2 |
AE binding protein 2 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of AEBP2 protein |
CTD |
PMID:28073184 |
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NCBI chr 4:173,527,881...173,566,033
Ensembl chr 4:173,528,344...173,593,100
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G |
Agfg1 |
ArfGAP with FG repeats 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of AGFG1 protein |
CTD |
PMID:28073184 |
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NCBI chr 9:84,124,845...84,182,615
Ensembl chr 9:84,125,120...84,178,128
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G |
Agpat2 |
1-acylglycerol-3-phosphate O-acyltransferase 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT2 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of AGPAT2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 3:9,416,837...9,428,567
Ensembl chr 3:9,416,843...9,428,371
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G |
Agpat5 |
1-acylglycerol-3-phosphate O-acyltransferase 5 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT5 mRNA |
CTD |
PMID:30547786 |
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NCBI chr16:70,939,480...70,985,745
Ensembl chr16:70,943,135...70,985,560
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G |
Ahdc1 |
AT hook, DNA binding motif, containing 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of AHDC1 protein |
CTD |
PMID:28073184 |
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NCBI chr 5:145,228,228...145,294,170
Ensembl chr 5:145,228,227...145,294,145
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G |
Ahnak |
AHNAK nucleoprotein |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of AHNAK protein |
CTD |
PMID:28073184 |
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NCBI chr 1:205,882,225...205,970,934
Ensembl chr 1:205,882,273...205,970,926
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G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] affects the expression of AHR mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AHR mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of AHR mRNA |
CTD |
PMID:30547786 PMID:33736254 |
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Aifm1 |
apoptosis inducing factor, mitochondria associated 1 |
multiple interactions affects localization |
EXP |
SQSTM1 protein affects the reaction [Palmitic Acid affects the localization of AIFM1 protein] |
CTD |
PMID:34774660 |
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NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
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G |
Akap1 |
A-kinase anchoring protein 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of AKAP1 protein |
CTD |
PMID:28073184 |
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NCBI chr10:73,621,021...73,654,123
Ensembl chr10:73,621,883...73,653,896
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G |
Akap13 |
A-kinase anchoring protein 13 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of AKAP13 protein |
CTD |
PMID:28073184 |
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NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646
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G |
Akt1 |
AKT serine/threonine kinase 1 |
decreases phosphorylation multiple interactions increases phosphorylation |
EXP ISO |
Palmitic Acid results in decreased phosphorylation of AKT1 protein [Oleic Acid co-treated with Palmitic Acid] results in decreased phosphorylation of AKT1 protein Palmitic Acid results in increased phosphorylation of AKT1 protein 4-phenylbutyric acid inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; [Palmitic Acid co-treated with Arsenic] affects the expression of AKT1 mRNA; Agmatine inhibits the reaction [Palmitic Acid results in decreased phosphorylation of AKT1 protein]; dorsomorphin inhibits the reaction [Agmatine inhibits the reaction [Palmitic Acid results in decreased phosphorylation of AKT1 protein]]; ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; Palmitic Acid inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]; Palmitic Acid inhibits the reaction [TNF protein results in increased phosphorylation of AKT1 protein]; STF 083010 inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]] 4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; geniposide inhibits the reaction [Palmitic Acid results in decreased phosphorylation of AKT1 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]; Palmitic Acid inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:22683933 PMID:22713545 PMID:22819839 PMID:25109277 PMID:26847930 PMID:30362509 PMID:32283200 PMID:33736254 PMID:35747990 More...
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Akt1s1 |
AKT1 substrate 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of AKT1S1 protein |
CTD |
PMID:28073184 |
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NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677
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G |
Alb |
albumin |
multiple interactions affects binding |
ISO |
[ALB protein binds to Palmitic Acid] promotes the reaction [ALB protein results in increased reduction of Dithionitrobenzoic Acid]; [ALB protein binds to Palmitic Acid] promotes the reaction [Pyruvaldehyde results in increased oxidation of ALB protein]; [ALB protein modified form binds to Palmitic Acid] which results in decreased reduction of Dithionitrobenzoic Acid; Palmitic Acid inhibits the reaction [Fenoprofen binds to ALB protein] ALB protein binds to Palmitic Acid; Palmitic Acid binds to ALB protein |
CTD |
PMID:9470966 PMID:12044178 PMID:25451573 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Alpl |
alkaline phosphatase, biomineralization associated |
multiple interactions increases expression |
EXP |
acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of ALPL mRNA]; CYBA mutant form inhibits the reaction [Palmitic Acid results in increased expression of ALPL mRNA]; U 0126 inhibits the reaction [Palmitic Acid results in increased expression of ALPL mRNA] |
CTD |
PMID:24080574 |
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NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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G |
Ampd2 |
adenosine monophosphate deaminase 2 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of AMPD2 protein |
CTD |
PMID:28073184 |
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NCBI chr 2:195,707,609...195,720,454
Ensembl chr 2:195,707,610...195,720,271
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G |
Angptl4 |
angiopoietin-like 4 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANGPTL4 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ANGPTL4 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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G |
Anln |
anillin, actin binding protein |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of ANLN protein |
CTD |
PMID:28073184 |
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NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538
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G |
Anxa2 |
annexin A2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANXA2 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ANXA2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
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G |
Apex2 |
apurinic/apyrimidinic endodeoxyribonuclease 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] affects the expression of APEX2 mRNA |
CTD |
PMID:33736254 |
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NCBI chr X:19,425,684...19,508,459
Ensembl chr X:19,487,419...19,508,439
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G |
Apob |
apolipoprotein B |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of APOB mRNA; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of APOB mRNA] |
CTD |
PMID:26854922 |
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NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
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G |
Apoe |
apolipoprotein E |
multiple interactions decreases expression |
ISO |
morroniside inhibits the reaction [Palmitic Acid results in decreased expression of APOE mRNA]; morroniside inhibits the reaction [Palmitic Acid results in decreased expression of APOE protein] Palmitic Acid results in decreased expression of APOE mRNA; Palmitic Acid results in decreased expression of APOE protein |
CTD |
PMID:34485530 |
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NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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G |
App |
amyloid beta precursor protein |
multiple interactions affects expression |
ISO |
[Palmitic Acid co-treated with Arsenic] affects the expression of APP mRNA Palmitic Acid affects the expression of APP mRNA |
CTD |
PMID:33736254 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Arg1 |
arginase 1 |
multiple interactions decreases expression affects expression |
EXP ISO |
AICA ribonucleotide inhibits the reaction [Palmitic Acid results in decreased expression of ARG1 mRNA]; Metformin inhibits the reaction [Palmitic Acid results in decreased expression of ARG1 mRNA]; resveratrol inhibits the reaction [Palmitic Acid results in decreased expression of ARG1 mRNA]; Salicylic Acid inhibits the reaction [Palmitic Acid results in decreased expression of ARG1 mRNA] Palmitic Acid results in decreased expression of ARG1 protein amlexanox affects the reaction [Palmitic Acid affects the expression of ARG1 mRNA]; amlexanox inhibits the reaction [Palmitic Acid results in decreased expression of ARG1 protein]; mifobate affects the reaction [Palmitic Acid affects the expression of ARG1 mRNA] [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ARG1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ARG1 mRNA |
CTD |
PMID:25108154 PMID:30547786 PMID:32905826 |
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NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
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G |
Arhgef12 |
Rho guanine nucleotide exchange factor 12 |
affects phosphorylation |
ISO |
Palmitic Acid affects the phosphorylation of ARHGEF12 protein |
CTD |
PMID:28073184 |
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NCBI chr 8:43,350,070...43,475,404
Ensembl chr 8:43,353,799...43,476,366
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G |
Arid1a |
AT-rich interaction domain 1A |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of ARID1A protein |
CTD |
PMID:28073184 |
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NCBI chr 5:145,908,173...145,981,552
Ensembl chr 5:145,908,181...145,985,564
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G |
Arl6ip4 |
ADP-ribosylation factor like GTPase 6 interacting protein 4 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of ARL6IP4 protein |
CTD |
PMID:28073184 |
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NCBI chr12:32,479,623...32,481,768
Ensembl chr12:32,479,625...32,481,799
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G |
Arvcf |
ARVCF, delta catenin family member |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of ARVCF protein |
CTD |
PMID:28073184 |
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NCBI chr11:82,588,137...82,645,832
Ensembl chr11:82,587,881...82,645,805
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G |
Asb2 |
ankyrin repeat and SOCS box-containing 2 |
increases expression |
ISO |
Palmitic Acid results in increased expression of ASB2 mRNA |
CTD |
PMID:32347412 |
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NCBI chr 6:122,474,754...122,511,014
Ensembl chr 6:122,474,756...122,510,854
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G |
Asxl2 |
ASXL transcriptional regulator 2 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of ASXL2 protein |
CTD |
PMID:28073184 |
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NCBI chr 6:26,425,017...26,514,899
Ensembl chr 6:26,425,954...26,507,477
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G |
Atf2 |
activating transcription factor 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] affects the expression of ATF2 mRNA |
CTD |
PMID:33736254 |
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NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
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G |
Atf4 |
activating transcription factor 4 |
increases expression multiple interactions |
ISO EXP |
Palmitic Acid results in increased expression of ATF4 mRNA; Palmitic Acid results in increased expression of ATF4 protein 4-phenylbutyric acid inhibits the reaction [Palmitic Acid results in increased expression of ATF4 mRNA]; GSK2656157 inhibits the reaction [Palmitic Acid results in increased expression of ATF4 mRNA]; GSK2656157 inhibits the reaction [Palmitic Acid results in increased expression of ATF4 protein] |
CTD |
PMID:30208301 PMID:34979142 PMID:36030031 |
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NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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G |
Atf6 |
activating transcription factor 6 |
multiple interactions increases expression |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of ATF6 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ATF6 mRNA Palmitic Acid results in increased expression of ATF6 mRNA [4-phenylbutyric acid co-treated with Palmitic Acid] results in decreased expression of ATF6 protein |
CTD |
PMID:32369900 PMID:36030031 |
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NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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G |
Atf7 |
activating transcription factor 7 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of ATF7 protein |
CTD |
PMID:28073184 |
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NCBI chr 7:133,660,491...133,750,902
Ensembl chr 7:133,663,294...133,750,848
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G |
Atf7ip |
activating transcription factor 7 interacting protein |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of ATF7IP protein |
CTD |
PMID:28073184 |
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NCBI chr 4:169,385,872...169,471,652
Ensembl chr 4:169,385,872...169,471,650
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G |
Atg10 |
autophagy related 10 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] affects the expression of ATG10 mRNA |
CTD |
PMID:33736254 |
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NCBI chr 2:22,109,304...22,398,313
Ensembl chr 2:22,108,426...22,398,233
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G |
Atg5 |
autophagy related 5 |
multiple interactions |
ISO EXP |
ATG5 protein promotes the reaction [resveratrol inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]] ATG5 protein promotes the reaction [C1QTNF9 protein inhibits the reaction [Palmitic Acid results in increased expression of CASP3 protein modified form]] |
CTD |
PMID:25943029 PMID:32278738 |
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NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
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G |
Atg7 |
autophagy related 7 |
decreases expression multiple interactions |
ISO |
Palmitic Acid results in decreased expression of ATG7 protein trigonelline inhibits the reaction [Palmitic Acid results in decreased expression of ATG7 protein] ATG7 protein affects the reaction [trigonelline inhibits the reaction [Palmitic Acid results in increased expression of PPARG protein]]; ATG7 protein affects the reaction [trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]]; trigonelline inhibits the reaction [Palmitic Acid results in decreased expression of ATG7 protein] |
CTD |
PMID:30208301 |
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NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
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G |
Atp11b |
ATPase phospholipid transporting 11B (putative) |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of ATP11B protein |
CTD |
PMID:28073184 |
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NCBI chr 2:118,585,348...118,691,076
Ensembl chr 2:118,585,342...118,690,232
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G |
Atp2a2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
multiple interactions |
ISO |
ATP2A2 protein promotes the reaction [7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased expression of XBP1 mRNA alternative form]] |
CTD |
PMID:29414781 |
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NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
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G |
Atp6v0c |
ATPase H+ transporting V0 subunit C |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] affects the expression of ATP6V0C mRNA |
CTD |
PMID:33736254 |
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NCBI chr10:13,196,204...13,202,580
Ensembl chr10:13,196,204...13,201,500
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G |
Atp7a |
ATPase copper transporting alpha |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of ATP7A protein |
CTD |
PMID:28073184 |
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NCBI chr X:71,094,144...71,201,550
Ensembl chr X:71,094,202...71,198,354
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G |
B4galt5 |
beta-1,4-galactosyltransferase 5 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of B4GALT5 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of B4GALT5 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 3:156,018,056...156,033,983
Ensembl chr 3:156,018,053...156,070,074
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G |
Bad |
BCL2-associated agonist of cell death |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of BAD protein |
CTD |
PMID:28073184 |
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NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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G |
Basp1 |
brain abundant, membrane attached signal protein 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of BASP1 protein |
CTD |
PMID:28073184 |
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NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043
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G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression multiple interactions affects expression |
ISO EXP |
Palmitic Acid results in increased expression of BAX 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in increased expression of BAX protein]]; [Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in increased expression of BAX protein]; MIR141 mRNA promotes the reaction [Palmitic Acid results in increased expression of BAX protein]; N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [[Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in increased expression of BAX protein]] Palmitic Acid affects the expression of BAX mRNA amlexanox inhibits the reaction [Palmitic Acid results in increased expression of BAX protein]; carnosol inhibits the reaction [Palmitic Acid results in increased expression of BAX protein]; PRDX3 protein inhibits the reaction [Palmitic Acid results in increased expression of BAX protein]; PRDX3 protein promotes the reaction [carnosol inhibits the reaction [Palmitic Acid results in increased expression of BAX protein]] 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of BAX mRNA]; [Palmitic Acid co-treated with Arsenic] affects the expression of BAX mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of BAX mRNA Palmitic Acid results in increased expression of BAX; Palmitic Acid results in increased expression of BAX protein |
CTD |
PMID:15945276 PMID:32369900 PMID:32905826 PMID:33736254 PMID:34678374 PMID:34897970 More...
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bbc3 |
Bcl-2 binding component 3 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Glucose] results in increased expression of BBC3 mRNA; SIRT1 protein mutant form inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased expression of BBC3 mRNA] |
CTD |
PMID:24451382 |
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NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression multiple interactions |
ISO EXP |
Palmitic Acid results in decreased expression of BCL2 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in decreased expression of BCL2 protein]]; [Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in decreased expression of BCL2 protein]; MIR141 mRNA promotes the reaction [Palmitic Acid results in decreased expression of BCL2 protein]; N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [[Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in decreased expression of BCL2 protein]] amlexanox inhibits the reaction [Palmitic Acid results in decreased expression of BCL2 protein]; carnosol inhibits the reaction [Palmitic Acid results in decreased expression of BCL2 protein]; PRDX3 protein promotes the reaction [carnosol inhibits the reaction [Palmitic Acid results in decreased expression of BCL2 protein]] 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of BCL2 mRNA]; [Palmitic Acid co-treated with Arsenic] results in increased expression of BCL2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of BCL2 mRNA Palmitic Acid results in decreased expression of BCL2; Palmitic Acid results in decreased expression of BCL2 protein |
CTD |
PMID:15945276 PMID:32369900 PMID:32905826 PMID:33736254 PMID:34678374 PMID:34897970 More...
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l13 |
Bcl2-like 13 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of BCL2L13 protein |
CTD |
PMID:28073184 |
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NCBI chr 4:154,056,116...154,112,890
Ensembl chr 4:154,056,127...154,108,985
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G |
Bcl3 |
BCL3, transcription coactivator |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of BCL3 protein |
CTD |
PMID:28073184 |
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NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
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G |
Bcl9l |
BCL9 like |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of BCL9L protein |
CTD |
PMID:28073184 |
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NCBI chr 8:44,811,977...44,840,611
Ensembl chr 8:44,811,977...44,840,611
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G |
Bclaf1 |
BCL2-associated transcription factor 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of BCLAF1 protein |
CTD |
PMID:28073184 |
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NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832
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G |
Becn1 |
beclin 1 |
multiple interactions increases expression decreases expression |
ISO EXP |
[Palmitic Acid co-treated with Arsenic] affects the expression of BECN1 mRNA; BECN1 protein promotes the reaction [Resveratrol inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]]; trigonelline inhibits the reaction [Palmitic Acid results in decreased expression of BECN1 protein] Palmitic Acid results in increased expression of BECN1 protein |
CTD |
PMID:25943029 PMID:30208301 PMID:33736254 PMID:34774660 |
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NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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G |
Bet1l |
Bet1 golgi vesicular membrane trafficking protein-like |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of BET1L protein |
CTD |
PMID:28073184 |
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NCBI chr 1:195,931,407...195,935,072
Ensembl chr 1:195,931,411...195,935,040
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G |
Bex2 |
brain expressed X-linked 2 |
increases expression |
ISO |
Palmitic Acid results in increased expression of BEX2 mRNA |
CTD |
PMID:32347412 |
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NCBI chr X:99,219,014...99,220,518
Ensembl chr X:99,219,014...99,220,958
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G |
Bex4 |
brain expressed, X-linked 4 |
increases expression |
ISO |
Palmitic Acid results in increased expression of BEX4 mRNA |
CTD |
PMID:32347412 |
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NCBI chr X:99,131,985...99,133,417
Ensembl chr X:99,131,942...99,133,531
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G |
Bfar |
bifunctional apoptosis regulator |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] affects the expression of BFAR mRNA |
CTD |
PMID:33736254 |
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NCBI chr10:1,552,019...1,585,040
Ensembl chr10:1,552,072...1,585,038
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G |
Bglap |
bone gamma-carboxyglutamate protein |
multiple interactions increases expression |
EXP |
acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of BGLAP mRNA]; CYBA mutant form inhibits the reaction [Palmitic Acid results in increased expression of BGLAP mRNA]; U 0126 inhibits the reaction [Palmitic Acid results in increased expression of BGLAP mRNA] |
CTD |
PMID:24080574 |
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NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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G |
Bid |
BH3 interacting domain death agonist |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] affects the expression of BID mRNA |
CTD |
PMID:33736254 |
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NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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G |
Bmal1 |
basic helix-loop-helix ARNT like 1 |
decreases expression |
ISO |
Palmitic Acid results in decreased expression of BMAL1 mRNA; Palmitic Acid results in decreased expression of BMAL1 protein |
CTD |
PMID:24442997 |
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NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
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G |
Bod1l1 |
biorientation of chromosomes in cell division 1-like 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of BOD1L1 protein |
CTD |
PMID:28073184 |
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NCBI chr14:69,108,483...69,163,255
Ensembl chr14:69,108,491...69,162,490
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G |
Braf |
B-Raf proto-oncogene, serine/threonine kinase |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of BRAF protein |
CTD |
PMID:28073184 |
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NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
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G |
Btg2 |
BTG anti-proliferation factor 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] affects the expression of BTG2 mRNA |
CTD |
PMID:33736254 |
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NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
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G |
Bysl |
bystin-like |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of BYSL protein |
CTD |
PMID:28073184 |
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NCBI chr 9:13,382,806...13,392,557
Ensembl chr 9:13,382,557...13,394,339
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G |
C9h2orf49 |
similar to human chromosome 2 open reading frame 49 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of C2ORF49 protein |
CTD |
PMID:28073184 |
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NCBI chr 9:45,371,396...45,382,123
Ensembl chr 9:45,371,430...45,382,120
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G |
Camsap2 |
calmodulin regulated spectrin-associated protein family, member 2 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of CAMSAP2 protein |
CTD |
PMID:28073184 |
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NCBI chr13:47,723,251...47,802,606
Ensembl chr13:47,723,121...47,802,597
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G |
Casp1 |
caspase 1 |
multiple interactions increases activity increases expression |
ISO EXP |
CA 074 methyl ester inhibits the reaction [Palmitic Acid results in increased cleavage of CASP1 protein]; NLRP3 inhibits the reaction [Palmitic Acid results in increased cleavage of CASP1 protein]; Palmitic Acid results in increased cleavage of and affects the localization of CASP1 protein Palmitic Acid results in increased activity of CASP1 protein imoxin inhibits the reaction [Palmitic Acid results in increased expression of CASP1 protein]; Lead promotes the reaction [Palmitic Acid results in increased activity of CASP1 protein]; Palmitic Acid promotes the reaction [Lead results in increased activity of CASP1 protein]; SRT1720 inhibits the reaction [Lead promotes the reaction [Palmitic Acid results in increased activity of CASP1 protein]]; SRT1720 inhibits the reaction [Palmitic Acid promotes the reaction [Lead results in increased activity of CASP1 protein]] |
CTD |
PMID:27689324 PMID:30259999 PMID:37244597 |
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NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp3 |
caspase 3 |
increases activity increases cleavage affects expression increases expression multiple interactions |
EXP ISO |
Palmitic Acid results in increased activity of CASP3 protein Palmitic Acid results in increased cleavage of CASP3 protein Palmitic Acid affects the expression of CASP3 mRNA Palmitic Acid results in increased expression of CASP3 mRNA; Palmitic Acid results in increased expression of CASP3 protein; Palmitic Acid results in increased expression of CASP3 protein modified form 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP3 mRNA]; 7-hydroxycoumarin inhibits the reaction [Palmitic Acid results in increased activity of CASP3 protein]; [Fructose co-treated with Palmitic Acid] results in increased activity of CASP3 protein; [Palmitic Acid co-treated with Arsenic] affects the expression of CASP3 mRNA; [Palmitic Acid co-treated with Glucose] results in increased cleavage of CASP3 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP3 mRNA; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [alpidem results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Clomipramine results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Clozapine results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Cyclosporine results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Dipyridamole results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Estrone results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [fipexide results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Flecainide results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Fluoxetine results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Fluvoxamine results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Imipramine results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Loratadine results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Mitoxantrone results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [nefazodone results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Nimodipine results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Nortriptyline results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Phentolamine results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Propranolol results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Pyrimethamine results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Riluzole results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Risperidone results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Spironolactone results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Ticlopidine results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [Troglitazone results in increased activity of CASP3 protein]; Palmitic Acid promotes the reaction [zileuton results in increased activity of CASP3 protein]; Scopoletin inhibits the reaction [Palmitic Acid results in increased activity of CASP3 protein]; SIRT1 protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased cleavage of CASP3 protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in increased expression of CASP3 protein modified form]]; [Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in increased expression of CASP3 protein modified form]; [T0901317 co-treated with Alitretinoin] promotes the reaction [Palmitic Acid results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of CASP3 mRNA]; ATG5 protein promotes the reaction [C1QTNF9 protein inhibits the reaction [Palmitic Acid results in increased expression of CASP3 protein modified form]]; geniposide inhibits the reaction [Palmitic Acid results in increased expression of and results in increased activity of CASP3 protein]; imoxin inhibits the reaction [Palmitic Acid results in increased expression of CASP3 mRNA]; imoxin inhibits the reaction [Palmitic Acid results in increased expression of CASP3 protein]; MIR141 mRNA promotes the reaction [Palmitic Acid results in increased expression of CASP3 protein modified form]; N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [[Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in increased expression of CASP3 protein modified form]]; Palmitic Acid results in increased cleavage of and results in increased activity of CASP3 protein; Palmitic Acid results in increased expression of and results in increased activity of CASP3 protein; parthenolide inhibits the reaction [Palmitic Acid results in increased expression of CASP3 mRNA]; pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased expression of CASP3 mRNA]; pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased expression of CASP3 protein]; SCD1 protein inhibits the reaction [Palmitic Acid results in increased activity of CASP3 protein]; SQSTM1 protein affects the reaction [Palmitic Acid results in increased cleavage of CASP3 protein]; T0901317 promotes the reaction [Palmitic Acid results in increased activity of CASP3 protein] amlexanox inhibits the reaction [Palmitic Acid results in increased cleavage of CASP3 protein]; Palmitic Acid results in decreased expression of and results in increased cleavage of CASP3 protein; PRDX3 protein inhibits the reaction [Palmitic Acid results in increased cleavage of CASP3 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Palmitic Acid results in decreased expression of and results in increased cleavage of CASP3 protein] |
CTD |
PMID:17194744 PMID:21687928 PMID:22413010 PMID:22700542 PMID:22819839 PMID:24451382 PMID:30259999 PMID:32278738 PMID:32369900 PMID:32730863 PMID:32905826 PMID:33604948 PMID:33736254 PMID:34678374 PMID:34774660 PMID:34897970 PMID:34979142 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp7 |
caspase 7 |
multiple interactions increases activity |
EXP ISO |
[T0901317 co-treated with Alitretinoin] promotes the reaction [Palmitic Acid results in increased activity of CASP7 protein]; T0901317 promotes the reaction [Palmitic Acid results in increased activity of CASP7 protein] Palmitic Acid promotes the reaction [alpidem results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Clomipramine results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Clozapine results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Cyclosporine results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Dipyridamole results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Estrone results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [fipexide results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Flecainide results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Fluoxetine results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Fluvoxamine results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Imipramine results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Loratadine results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Mitoxantrone results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [nefazodone results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Nimodipine results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Nortriptyline results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Phentolamine results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Pyrimethamine results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Riluzole results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Risperidone results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Spironolactone results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Ticlopidine results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [Troglitazone results in increased activity of CASP7 protein]; Palmitic Acid promotes the reaction [zileuton results in increased activity of CASP7 protein] |
CTD |
PMID:17194744 PMID:22413010 PMID:22700542 |
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NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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G |
Casp9 |
caspase 9 |
multiple interactions increases expression |
ISO EXP |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP9 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP9 mRNA Palmitic Acid results in increased expression of CASP9 protein modified form 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in increased expression of CASP9 protein modified form]]; [Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in increased expression of CASP9 protein modified form]; MIR141 mRNA promotes the reaction [Palmitic Acid results in increased expression of CASP9 protein modified form]; N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [[Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in increased expression of CASP9 protein modified form]] |
CTD |
PMID:32369900 PMID:34897970 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
multiple interactions |
EXP ISO |
[Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased activity of CAT protein; [Oleic Acid co-treated with Palmitic Acid] results in increased activity of CAT protein [Palmitic Acid co-treated with Arsenic] affects the expression of CAT mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CAT mRNA |
CTD |
PMID:26854922 PMID:30547786 PMID:33736254 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cav1 |
caveolin 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of CAV1 protein |
CTD |
PMID:28073184 |
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NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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G |
Cav2 |
caveolin 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of CAV2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244
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G |
Cbx3 |
chromobox 3 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of CBX3 protein |
CTD |
PMID:28073184 |
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NCBI chr 4:80,545,450...80,559,284
Ensembl chr 4:80,546,010...80,559,283
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G |
Ccdc6 |
coiled-coil domain containing 6 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of CCDC6 protein |
CTD |
PMID:28073184 |
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NCBI chr20:18,432,177...18,528,186
Ensembl chr20:18,433,695...18,528,658
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G |
Ccdc9 |
coiled-coil domain containing 9 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of CCDC9 protein |
CTD |
PMID:28073184 |
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NCBI chr 1:76,978,312...76,991,673
Ensembl chr 1:76,974,091...76,991,607
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions increases expression |
EXP ISO |
AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of CCL2 mRNA]; Metformin inhibits the reaction [Palmitic Acid results in increased expression of CCL2 mRNA]; resveratrol inhibits the reaction [Palmitic Acid results in increased expression of CCL2 mRNA]; Salicylic Acid inhibits the reaction [Palmitic Acid results in increased expression of CCL2 mRNA] (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CCL2 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein; Bezafibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein] Palmitic Acid results in increased expression of CCL2 mRNA; Palmitic Acid results in increased expression of CCL2 protein Quercetin inhibits the reaction [Palmitic Acid results in increased expression of CCL2 mRNA]; Quercetin inhibits the reaction [Palmitic Acid results in increased expression of CCL2 protein] |
CTD |
PMID:25108154 PMID:25614714 PMID:32613381 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions increases expression |
ISO |
AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of CCL3 mRNA]; Bezafibrate inhibits the reaction [Palmitic Acid results in increased expression of CCL3 mRNA]; Capsaicin inhibits the reaction [Palmitic Acid results in increased expression of CCL3 mRNA]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [Capsaicin inhibits the reaction [Palmitic Acid results in increased expression of CCL3 mRNA]] |
CTD |
PMID:21745629 |
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NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO |
[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CCL5 mRNA |
CTD |
PMID:32613381 |
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NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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G |
Ccn2 |
cellular communication network factor 2 |
increases expression multiple interactions |
EXP |
Palmitic Acid results in increased expression of CCN2 protein CXCL12 protein inhibits the reaction [Palmitic Acid results in increased expression of CCN2 protein]; CXCR7 protein promotes the reaction [CXCL12 protein inhibits the reaction [Palmitic Acid results in increased expression of CCN2 protein]]; KLF15 protein promotes the reaction [CXCL12 protein inhibits the reaction [Palmitic Acid results in increased expression of CCN2 protein]]; MAPK11 protein promotes the reaction [CXCL12 protein inhibits the reaction [Palmitic Acid results in increased expression of CCN2 protein]] |
CTD |
PMID:34310909 |
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NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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G |
Ccnd1 |
cyclin D1 |
decreases expression multiple interactions |
EXP |
Palmitic Acid results in decreased expression of CCND1 protein CYLD protein affects the reaction [Palmitic Acid results in decreased expression of CCND1 protein]; PKF115-584 inhibits the reaction [CYLD protein affects the reaction [Palmitic Acid results in decreased expression of CCND1 protein]] |
CTD |
PMID:34774660 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Cd14 |
CD14 molecule |
increases expression multiple interactions |
ISO |
Palmitic Acid results in increased expression of CD14 mRNA amlexanox inhibits the reaction [Palmitic Acid results in increased expression of CD14 mRNA] |
CTD |
PMID:32905826 |
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NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
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G |
Cd36 |
CD36 molecule |
increases expression multiple interactions |
ISO |
Palmitic Acid results in increased expression of CD36 protein (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CD36 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CD36 mRNA]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA] trigonelline inhibits the reaction [Palmitic Acid results in increased expression of CD36 protein] |
CTD |
PMID:30208301 PMID:32613381 PMID:36347319 |
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NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cd68 |
Cd68 molecule |
increases expression multiple interactions |
ISO |
Palmitic Acid results in increased expression of CD68 mRNA amlexanox inhibits the reaction [Palmitic Acid results in increased expression of CD68 mRNA] |
CTD |
PMID:32905826 |
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NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
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G |
Cdc42ep4 |
CDC42 effector protein 4 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of CDC42EP4 protein |
CTD |
PMID:28073184 |
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NCBI chr10:98,772,613...98,797,924
Ensembl chr10:98,772,495...98,797,695
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G |
Cdh15 |
cadherin 15 |
increases expression |
ISO |
Palmitic Acid results in increased expression of CDH15 mRNA |
CTD |
PMID:32347412 |
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NCBI chr19:50,903,757...50,927,151
Ensembl chr19:50,903,638...50,927,105
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G |
Cdh3 |
cadherin 3 |
increases expression |
ISO |
Palmitic Acid results in increased expression of CDH3 mRNA |
CTD |
PMID:32347412 |
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NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CDKN1A mRNA]; [Palmitic Acid co-treated with Glucose] results in increased expression of CDKN1A mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CDKN1A mRNA; SIRT1 protein mutant form inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased expression of CDKN1A mRNA] |
CTD |
PMID:24451382 PMID:32369900 |
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of CDKN1B protein |
CTD |
PMID:28073184 |
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NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
multiple interactions |
EXP ISO |
[Palmitic Acid co-treated with Sincalide] results in increased expression of CEBPA mRNA; [Palmitic Acid co-treated with Sincalide] results in increased expression of CEBPA protein; Quercetin inhibits the reaction [[Sincalide co-treated with Palmitic Acid] results in increased expression of CEBPA protein] [Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CEBPA mRNA; Palmitic Acid promotes the reaction [[sodium arsenite co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CEBPA mRNA]; Palmitic Acid promotes the reaction [sodium arsenite results in decreased expression of CEBPA mRNA]; sodium arsenite promotes the reaction [[Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CEBPA mRNA] |
CTD |
PMID:26873426 PMID:34968464 |
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NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Sincalide] results in increased expression of CEBPB mRNA; [Palmitic Acid co-treated with Sincalide] results in increased expression of CEBPB protein; Quercetin inhibits the reaction [[Sincalide co-treated with Palmitic Acid] results in increased expression of CEBPB protein] |
CTD |
PMID:26873426 |
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NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Cep170b |
centrosomal protein 170B |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of CEP170B protein |
CTD |
PMID:28073184 |
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NCBI chr 6:131,780,935...131,806,658
Ensembl chr 6:131,778,957...131,806,658
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G |
Cgas |
cyclic GMP-AMP synthase |
increases expression |
EXP |
Palmitic Acid results in increased expression of CGAS mRNA; Palmitic Acid results in increased expression of CGAS protein |
CTD |
PMID:35235096 |
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NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496
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G |
Chaf1a |
chromatin assembly factor 1 subunit A |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of CHAF1A protein |
CTD |
PMID:28073184 |
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NCBI chr 9:873,953...900,701
Ensembl chr 9:874,051...900,654
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G |
Chchd3 |
coiled-coil-helix-coiled-coil-helix domain containing 3 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of CHCHD3 protein |
CTD |
PMID:28073184 |
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NCBI chr 4:61,360,352...61,616,850
Ensembl chr 4:61,360,353...61,616,847
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G |
Chd3 |
chromodomain helicase DNA binding protein 3 |
affects phosphorylation |
ISO |
Palmitic Acid affects the phosphorylation of CHD3 protein |
CTD |
PMID:28073184 |
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NCBI chr10:54,063,629...54,090,030
Ensembl chr10:54,063,629...54,090,047
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G |
chromosome 11 open reading frame 96 |
similar to human |
increases expression |
ISO |
Palmitic Acid results in increased expression of C11ORF96 mRNA |
CTD |
PMID:32347412 |
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NCBI chr 3:79,920,125...79,921,368
Ensembl chr 3:79,920,129...79,921,523
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G |
Cidec |
cell death-inducing DFFA-like effector c |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CIDEC protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CIDEC mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
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G |
Clip1 |
CAP-GLY domain containing linker protein 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of CLIP1 protein |
CTD |
PMID:28073184 |
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NCBI chr12:32,910,932...33,017,891
Ensembl chr12:32,910,977...33,017,884
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G |
Clock |
clock circadian regulator |
decreases expression |
ISO |
Palmitic Acid results in decreased expression of CLOCK mRNA; Palmitic Acid results in decreased expression of CLOCK protein |
CTD |
PMID:24442997 |
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NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400
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G |
Cnot2 |
CCR4-NOT transcription complex, subunit 2 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of CNOT2 protein |
CTD |
PMID:28073184 |
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NCBI chr 7:52,130,445...52,222,338
Ensembl chr 7:52,130,441...52,223,575
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G |
Cobll1 |
cordon-bleu WH2 repeat protein-like 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of COBLL1 protein |
CTD |
PMID:28073184 |
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NCBI chr 3:49,753,260...49,915,168
Ensembl chr 3:49,753,262...49,915,194
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions increases expression |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of COL1A1 mRNA Palmitic Acid results in increased expression of COL1A1 mRNA [Palmitic Acid co-treated with Ethanol] results in increased expression of COL1A1 mRNA |
CTD |
PMID:26187275 PMID:37271273 |
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NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Coro2b |
coronin 2B |
increases expression |
ISO |
Palmitic Acid results in increased expression of CORO2B mRNA |
CTD |
PMID:32347412 |
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NCBI chr 8:62,906,861...63,017,295
Ensembl chr 8:62,906,867...63,017,302
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G |
Cox5a |
cytochrome c oxidase subunit 5A |
decreases expression increases methylation multiple interactions |
EXP |
Palmitic Acid results in decreased expression of COX5A mRNA Palmitic Acid results in increased methylation of COX5A promoter decitabine inhibits the reaction [Palmitic Acid results in decreased expression of COX5A mRNA]; decitabine inhibits the reaction [Palmitic Acid results in increased methylation of COX5A promoter] |
CTD |
PMID:25436770 |
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NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
multiple interactions decreases expression increases expression |
ISO EXP |
(R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of CPT1A protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CPT1A mRNA; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of CPT1A protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CPT1A mRNA; Bezafibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Capsaicin promotes the reaction [Palmitic Acid results in increased expression of CPT1A mRNA]; Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; isosilybin promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA]; Ivermectin inhibits the reaction [Palmitic Acid results in increased expression of CPT1A mRNA]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Permethrin inhibits the reaction [Palmitic Acid results in increased expression of CPT1A mRNA]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA] Palmitic Acid results in decreased expression of CPT1A mRNA [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of CPT1A mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A protein; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of CPT1A mRNA]; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A protein]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of CPT1A mRNA]; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA]; Triiodothyronine promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA] amlexanox inhibits the reaction [Palmitic Acid results in decreased expression of CPT1A mRNA]; obeticholic acid promotes the reaction [Palmitic Acid results in increased expression of CPT1A mRNA] |
CTD |
PMID:21745629 PMID:25048947 PMID:26190035 PMID:26655953 PMID:26854922 PMID:30547786 PMID:30738135 PMID:32613381 PMID:32905826 PMID:36347319 More...
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NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions |
ISO |
Palmitic Acid inhibits the reaction [SMIM20 protein results in increased phosphorylation of CREB1 protein] |
CTD |
PMID:30716364 |
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NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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G |
Crip2 |
cysteine-rich protein 2 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of CRIP2 protein |
CTD |
PMID:28073184 |
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NCBI chr 6:132,221,120...132,226,066
Ensembl chr 6:132,221,082...132,226,065
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G |
Crybg1 |
crystallin beta-gamma domain containing 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of CRYBG1 protein |
CTD |
PMID:28073184 |
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NCBI chr20:47,425,030...47,496,918
Ensembl chr20:47,426,183...47,621,392
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G |
Cspp1 |
centrosome and spindle pole associated protein 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of CSPP1 protein |
CTD |
PMID:28073184 |
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NCBI chr 5:9,077,161...9,192,402
Ensembl chr 5:9,077,161...9,193,377
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G |
Ctnnb1 |
catenin beta 1 |
decreases expression multiple interactions |
EXP |
Palmitic Acid results in decreased expression of CTNNB1 protein CYLD protein affects the reaction [Palmitic Acid results in decreased expression of CTNNB1 protein] |
CTD |
PMID:34774660 |
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NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Ctnnd1 |
catenin delta 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of CTNND1 protein |
CTD |
PMID:28073184 |
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NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516
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G |
Ctr9 |
CTR9 homolog, Paf1/RNA polymerase II complex component |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of CTR9 protein |
CTD |
PMID:28073184 |
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NCBI chr 1:165,137,277...165,167,303
Ensembl chr 1:165,137,215...165,167,303
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G |
Cttn |
cortactin |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of CTTN protein |
CTD |
PMID:28073184 |
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NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of CXCL10 mRNA |
CTD |
PMID:30547786 |
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NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
multiple interactions |
EXP |
CXCL12 protein inhibits the reaction [Palmitic Acid results in decreased expression of KLF15 protein]; CXCL12 protein inhibits the reaction [Palmitic Acid results in increased expression of CCN2 protein]; CXCR7 protein promotes the reaction [CXCL12 protein inhibits the reaction [Palmitic Acid results in decreased expression of KLF15 protein]]; CXCR7 protein promotes the reaction [CXCL12 protein inhibits the reaction [Palmitic Acid results in increased expression of CCN2 protein]]; KLF15 protein promotes the reaction [CXCL12 protein inhibits the reaction [Palmitic Acid results in increased expression of CCN2 protein]]; MAPK11 protein promotes the reaction [CXCL12 protein inhibits the reaction [Palmitic Acid results in decreased expression of KLF15 protein]]; MAPK11 protein promotes the reaction [CXCL12 protein inhibits the reaction [Palmitic Acid results in increased expression of CCN2 protein]] |
CTD |
PMID:34310909 |
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NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CXCL2 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of CXCL2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cyba |
cytochrome b-245 alpha chain |
multiple interactions |
EXP |
CYBA mutant form inhibits the reaction [Palmitic Acid results in increased expression of ALPL mRNA]; CYBA mutant form inhibits the reaction [Palmitic Acid results in increased expression of BGLAP mRNA]; CYBA mutant form inhibits the reaction [Palmitic Acid results in increased expression of RUNX2 mRNA]; CYBA mutant form inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK1 protein]; CYBA mutant form inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:24080574 |
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NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
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G |
Cybb |
cytochrome b-245 beta chain |
increases expression multiple interactions |
EXP ISO |
Palmitic Acid results in increased expression of CYBB mRNA geraniol inhibits the reaction [Palmitic Acid results in increased expression of CYBB protein] acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of CYBB mRNA]; U 0126 inhibits the reaction [Palmitic Acid results in increased expression of CYBB mRNA] |
CTD |
PMID:24080574 PMID:27107694 |
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NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
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G |
Cycs |
cytochrome c, somatic |
multiple interactions |
ISO |
[Fructose co-treated with Palmitic Acid] results in increased expression of CYCS protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of CYCS protein] |
CTD |
PMID:32730863 |
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyld |
CYLD lysine 63 deubiquitinase |
multiple interactions increases expression |
EXP |
CYLD protein affects the reaction [Palmitic Acid results in decreased expression of CCND1 protein]; CYLD protein affects the reaction [Palmitic Acid results in decreased expression of CTNNB1 protein]; CYLD protein affects the reaction [Palmitic Acid results in increased expression of SQSTM1 protein]; CYLD protein affects the reaction [Palmitic Acid results in increased phosphorylation of GSK3B protein]; PKF115-584 inhibits the reaction [CYLD protein affects the reaction [Palmitic Acid results in decreased expression of CCND1 protein]]; PKF115-584 inhibits the reaction [CYLD protein affects the reaction [Palmitic Acid results in increased expression of SQSTM1 protein]]; PKF115-584 inhibits the reaction [CYLD protein affects the reaction [Palmitic Acid results in increased phosphorylation of GSK3B protein]] Palmitic Acid results in increased expression of CYLD mRNA; Palmitic Acid results in increased expression of CYLD protein |
CTD |
PMID:34774660 |
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NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658
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G |
Cyp24a1 |
cytochrome P450, family 24, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP24A1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CYP24A1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
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G |
Cyp26a1 |
cytochrome P450, family 26, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP26A1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CYP26A1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
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G |
Cyp26b1 |
cytochrome P450, family 26, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CYP26B1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions increases expression |
EXP ISO |
[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP2E1 mRNA; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP2E1 mRNA] Palmitic Acid results in increased expression of CYP2E1 mRNA; Palmitic Acid results in increased expression of CYP2E1 protein amlexanox inhibits the reaction [Palmitic Acid results in increased expression of CYP2E1 mRNA]; amlexanox inhibits the reaction [Palmitic Acid results in increased expression of CYP2E1 protein] |
CTD |
PMID:26854922 PMID:32905826 |
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp4a1 |
cytochrome P450, family 4, subfamily a, polypeptide 1 |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in decreased expression of CYP4A1 mRNA |
CTD |
PMID:26854922 |
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NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
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G |
Dab2 |
DAB adaptor protein 2 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of DAB2 protein |
CTD |
PMID:28073184 |
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NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
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G |
Dab2ip |
DAB2 interacting protein |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of DAB2IP protein |
CTD |
PMID:28073184 |
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NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280
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G |
Dapk1 |
death associated protein kinase 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] affects the expression of DAPK1 mRNA |
CTD |
PMID:33736254 |
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NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
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G |
Dbn1 |
drebrin 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of DBN1 protein |
CTD |
PMID:28073184 |
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NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984
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G |
Dbnl |
drebrin-like |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of DBNL protein |
CTD |
PMID:28073184 |
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NCBI chr14:80,666,115...80,681,155
Ensembl chr14:80,666,124...80,681,155
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression multiple interactions |
ISO EXP |
Palmitic Acid results in increased expression of DDIT3 mRNA; Palmitic Acid results in increased expression of DDIT3 protein Scopoletin inhibits the reaction [Palmitic Acid results in increased expression of DDIT3 mRNA] 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of DDIT3 mRNA]; [Palmitic Acid co-treated with Arsenic] results in increased expression of DDIT3 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of DDIT3 mRNA; Ivermectin promotes the reaction [Palmitic Acid results in increased expression of DDIT3 protein]; Permethrin inhibits the reaction [Palmitic Acid results in increased expression of DDIT3 mRNA] 4-phenylbutyric acid promotes the reaction [Palmitic Acid results in increased expression of DDIT3 mRNA]; 7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased expression of DDIT3 protein]; GSK2656157 inhibits the reaction [Palmitic Acid results in increased expression of DDIT3 mRNA]; GSK2656157 inhibits the reaction [Palmitic Acid results in increased expression of DDIT3 protein]; Thapsigargin inhibits the reaction [7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased expression of DDIT3 protein]] |
CTD |
PMID:29414781 PMID:30208301 PMID:30738135 PMID:32369900 PMID:33736254 PMID:34979142 PMID:36030031 More...
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddx17 |
DEAD-box helicase 17 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of DDX17 protein |
CTD |
PMID:28073184 |
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NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193
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G |
Ddx20 |
DEAD-box helicase 20 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of DDX20 protein |
CTD |
PMID:28073184 |
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NCBI chr 2:193,158,761...193,168,484
Ensembl chr 2:193,158,823...193,166,774
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G |
Ddx24 |
DEAD-box helicase 24 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of DDX24 protein |
CTD |
PMID:28073184 |
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NCBI chr 6:122,564,767...122,582,032
Ensembl chr 6:122,564,767...122,581,927
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G |
Derl1 |
derlin 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of DERL1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 7:89,404,413...89,427,095
Ensembl chr 7:89,404,417...89,427,145
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G |
Dgat1 |
diacylglycerol O-acyltransferase 1 |
increases expression multiple interactions |
ISO |
Palmitic Acid results in increased expression of DGAT1 mRNA 7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased expression of DGAT1 mRNA]; amlexanox inhibits the reaction [Palmitic Acid results in increased expression of DGAT1 mRNA] |
CTD |
PMID:29414781 PMID:32905826 |
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NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
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G |
Dhx29 |
DExH-box helicase 29 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of DHX29 protein |
CTD |
PMID:28073184 |
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NCBI chr 2:44,560,653...44,611,450
Ensembl chr 2:44,560,714...44,611,445
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G |
Dip2b |
disco-interacting protein 2 homolog B |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of DIP2B protein |
CTD |
PMID:28073184 |
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NCBI chr 7:131,174,575...131,350,417
Ensembl chr 7:131,174,567...131,349,092
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G |
Dkc1 |
dyskerin pseudouridine synthase 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of DKC1 protein |
CTD |
PMID:28073184 |
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G |
Dmxl1 |
Dmx-like 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of DMXL1 protein |
CTD |
PMID:28073184 |
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NCBI chr18:42,993,292...43,163,457
Ensembl chr18:42,993,340...43,163,456
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G |
Dnajc15 |
DnaJ heat shock protein family (Hsp40) member C15 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of DNAJC15 protein |
CTD |
PMID:28073184 |
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NCBI chr15:53,182,060...53,249,675
Ensembl chr15:53,184,855...53,249,675
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G |
Dnajc6 |
DnaJ heat shock protein family (Hsp40) member C6 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of DNAJC6 protein |
CTD |
PMID:28073184 |
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NCBI chr 5:116,120,069...116,283,448
Ensembl chr 5:116,119,676...116,283,448
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G |
Dnm1l |
dynamin 1-like |
multiple interactions increases expression |
ISO |
[Fructose co-treated with Palmitic Acid] results in increased expression of DNM1L protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of DNM1L protein] Palmitic Acid results in increased expression of DNM1L protein carnosol inhibits the reaction [Palmitic Acid results in increased expression of DNM1L protein]; PRDX3 protein inhibits the reaction [Palmitic Acid results in increased expression of DNM1L protein]; PRDX3 protein promotes the reaction [carnosol inhibits the reaction [Palmitic Acid results in increased expression of DNM1L protein]] |
CTD |
PMID:32730863 PMID:34678374 |
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NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
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G |
Dnmt1 |
DNA methyltransferase 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of DNMT1 protein |
CTD |
PMID:28073184 |
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NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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G |
Dock7 |
dedicator of cytokinesis 7 |
affects phosphorylation |
ISO |
Palmitic Acid affects the phosphorylation of DOCK7 protein |
CTD |
PMID:28073184 |
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NCBI chr 5:113,599,371...113,782,871
Ensembl chr 5:113,600,198...113,782,813
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G |
Dot1l |
DOT1 like histone lysine methyltransferase |
affects phosphorylation |
ISO |
Palmitic Acid affects the phosphorylation of DOT1L protein |
CTD |
PMID:28073184 |
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NCBI chr 7:8,918,764...8,959,474
Ensembl chr 7:8,917,786...8,956,475
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G |
Dpf2 |
double PHD fingers 2 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of DPF2 protein |
CTD |
PMID:28073184 |
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NCBI chr 1:203,183,674...203,199,037
Ensembl chr 1:203,183,686...203,198,983
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G |
Dst |
dystonin |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of DST mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of DST mRNA |
CTD |
PMID:30547786 |
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NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615
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G |
Dtl |
denticleless E3 ubiquitin protein ligase homolog |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of DTL protein |
CTD |
PMID:28073184 |
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NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890
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G |
Dync1h1 |
dynein cytoplasmic 1 heavy chain 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1H1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of DYNC1H1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:129,615,208...129,680,888
Ensembl chr 6:129,609,397...129,680,883
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G |
Dync1i1 |
dynein cytoplasmic 1 intermediate chain 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1I1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of DYNC1I1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:33,852,597...34,166,159
Ensembl chr 4:33,852,927...34,166,149
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G |
Dync1li1 |
dynein cytoplasmic 1 light intermediate chain 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of DYNC1LI1 protein |
CTD |
PMID:28073184 |
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NCBI chr 8:114,376,649...114,410,297
Ensembl chr 8:114,376,662...114,410,934
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G |
Dync1li2 |
dynein, cytoplasmic 1 light intermediate chain 2 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of DYNC1LI2 protein |
CTD |
PMID:28073184 |
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NCBI chr19:531,783...554,670
Ensembl chr19:531,812...554,670
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G |
Edc3 |
enhancer of mRNA decapping 3 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of EDC3 protein |
CTD |
PMID:28073184 |
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NCBI chr 8:58,106,147...58,151,685
Ensembl chr 8:58,106,175...58,151,671
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G |
Edn1 |
endothelin 1 |
increases expression decreases expression multiple interactions |
ISO |
Palmitic Acid results in increased expression of EDN1 mRNA; Palmitic Acid results in increased expression of EDN1 protein Palmitic Acid results in decreased expression of EDN1 protein Agmatine inhibits the reaction [Palmitic Acid results in decreased expression of EDN1 protein] |
CTD |
PMID:16895544 PMID:35747990 |
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NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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G |
Ednra |
endothelin receptor type A |
multiple interactions decreases expression |
ISO |
Agmatine inhibits the reaction [Palmitic Acid results in decreased expression of EDNRA protein] |
CTD |
PMID:35747990 |
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NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
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G |
Efhd2 |
EF-hand domain family, member D2 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of EFHD2 protein |
CTD |
PMID:28073184 |
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NCBI chr 5:154,160,945...154,176,980
Ensembl chr 5:154,160,946...154,176,980
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of EGFR mRNA |
CTD |
PMID:30547786 |
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NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Egr1 |
early growth response 1 |
increases expression |
ISO |
Palmitic Acid results in increased expression of EGR1 mRNA |
CTD |
PMID:32347412 |
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NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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G |
Eif2ak2 |
eukaryotic translation initiation factor 2-alpha kinase 2 |
multiple interactions increases phosphorylation increases expression |
EXP ISO |
imoxin inhibits the reaction [Palmitic Acid results in increased expression of EIF2AK2 mRNA]; imoxin inhibits the reaction [Palmitic Acid results in increased expression of EIF2AK2 protein] Palmitic Acid results in increased phosphorylation of EIF2AK2 protein Palmitic Acid results in increased expression of EIF2AK2 mRNA; Palmitic Acid results in increased expression of EIF2AK2 protein |
CTD |
PMID:30259999 PMID:30794626 |
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NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
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G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions increases expression |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of EIF2AK3 mRNA]; [Palmitic Acid co-treated with Oleic Acid] affects the expression of EIF2AK3 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of EIF2AK3 mRNA Palmitic Acid results in increased expression of EIF2AK3 mRNA; Palmitic Acid results in increased expression of EIF2AK3 protein |
CTD |
PMID:30547786 PMID:32369900 PMID:36030031 |
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NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
multiple interactions increases phosphorylation |
ISO |
7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased phosphorylation of EIF2S1 protein]; GSK2656157 inhibits the reaction [Palmitic Acid results in increased phosphorylation of EIF2S1 protein]; Thapsigargin inhibits the reaction [7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased phosphorylation of EIF2S1 protein]]; trigonelline inhibits the reaction [Palmitic Acid results in increased phosphorylation of EIF2S1 protein] |
CTD |
PMID:29414781 PMID:30208301 PMID:36030031 |
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NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
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G |
Eif4b |
eukaryotic translation initiation factor 4B |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of EIF4B protein |
CTD |
PMID:28073184 |
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NCBI chr 7:133,206,637...133,228,436
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G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of EIF4EBP1 protein |
CTD |
PMID:28073184 |
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NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
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G |
Eif5b |
eukaryotic translation initiation factor 5B |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of EIF5B protein |
CTD |
PMID:28073184 |
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NCBI chr 9:40,222,769...40,277,482
Ensembl chr 9:40,222,898...40,277,482
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G |
Elovl6 |
ELOVL fatty acid elongase 6 |
multiple interactions |
ISO |
(R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ELOVL6 mRNA; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA] |
CTD |
PMID:30547786 PMID:32613381 |
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NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
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G |
Eno3 |
enolase 3 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ENO3 mRNA |
CTD |
PMID:30547786 |
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NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921
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G |
Ercc1 |
ERCC excision repair 1, endonuclease non-catalytic subunit |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] affects the expression of ERCC1 mRNA |
CTD |
PMID:33736254 |
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NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
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G |
Erlin1 |
ER lipid raft associated 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ERLIN1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394
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G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions increases expression increases phosphorylation |
EXP ISO |
[Palmitic Acid co-treated with Sincalide] results in increased expression of ERN1 mRNA; [Palmitic Acid co-treated with Sincalide] results in increased expression of ERN1 protein; Quercetin inhibits the reaction [[Sincalide co-treated with Palmitic Acid] results in increased expression of ERN1 protein] Palmitic Acid results in increased expression of ERN1 mRNA; Palmitic Acid results in increased expression of ERN1 protein 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of ERN1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ERN1 mRNA; Deferoxamine promotes the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein]; ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein]; Sirolimus inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] 4-phenylbutyric acid promotes the reaction [Palmitic Acid results in increased expression of ERN1 mRNA]; 7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein]; baicalin inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein]; Thapsigargin inhibits the reaction [7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein]]; ursodoxicoltaurine inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] |
CTD |
PMID:26873426 PMID:29031535 PMID:29414781 PMID:32283200 PMID:32369900 PMID:36030031 More...
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NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
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G |
Esf1 |
ESF1 nucleolar pre-rRNA processing protein homolog |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of ESF1 protein |
CTD |
PMID:28073184 |
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NCBI chr 3:127,454,744...127,507,941
Ensembl chr 3:127,454,811...127,507,817
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G |
Exosc9 |
exosome component 9 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of EXOSC9 protein |
CTD |
PMID:28073184 |
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NCBI chr 2:119,416,028...119,426,981
Ensembl chr 2:119,388,715...119,427,051
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G |
Fabp1 |
fatty acid binding protein 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of FABP1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
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G |
Fam117b |
family with sequence similarity 117, member B |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of FAM117B protein |
CTD |
PMID:28073184 |
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NCBI chr 9:61,340,284...61,418,531
Ensembl chr 9:61,340,249...61,408,483
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G |
Fam120a |
family with sequence similarity 120 member A |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of FAM120A protein |
CTD |
PMID:28073184 |
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NCBI chr17:15,684,233...15,774,964
Ensembl chr17:15,684,233...15,774,964
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G |
Fam83b |
family with sequence similarity 83, member B |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of FAM83B protein |
CTD |
PMID:28073184 |
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NCBI chr 8:77,287,351...77,363,795
Ensembl chr 8:77,287,351...77,363,795
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G |
Fas |
Fas cell surface death receptor |
increases expression multiple interactions |
ISO EXP |
Palmitic Acid results in increased expression of FAS protein [Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS protein; [Palmitic Acid co-treated with Arsenic] affects the expression of FAS mRNA; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS protein]; Palmitic Acid inhibits the reaction [Permethrin results in decreased expression of FAS mRNA] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS mRNA; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS mRNA] |
CTD |
PMID:21687928 PMID:26190035 PMID:30738135 PMID:33736254 PMID:36347319 |
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NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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G |
Fasn |
fatty acid synthase |
multiple interactions increases phosphorylation increases expression |
ISO EXP |
[osteum co-treated with Palmitic Acid] promotes the reaction [decabromobiphenyl ether results in increased expression of FASN protein]; [osteum co-treated with Palmitic Acid] results in increased expression of FASN protein; acanthoic acid inhibits the reaction [Palmitic Acid results in increased expression of FASN mRNA]; amlexanox inhibits the reaction [Palmitic Acid results in increased expression of FASN mRNA]; decabromobiphenyl ether promotes the reaction [[osteum co-treated with Palmitic Acid] results in increased expression of FASN protein]; GW 3965 inhibits the reaction [Palmitic Acid results in increased expression of FASN mRNA]; obeticholic acid inhibits the reaction [Palmitic Acid results in increased expression of FASN mRNA]; Orlistat inhibits the reaction [FASN protein results in increased chemical synthesis of Palmitic Acid] [Fructose co-treated with Palmitic Acid] results in increased expression of FASN protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of FASN protein] Palmitic Acid results in increased phosphorylation of FASN protein [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of FASN mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of FASN mRNA Palmitic Acid results in increased expression of FASN mRNA; Palmitic Acid results in increased expression of FASN protein |
CTD |
PMID:21213365 PMID:26655953 PMID:26854922 PMID:28073184 PMID:29414781 PMID:31421115 PMID:32730863 PMID:32905826 PMID:34757160 More...
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NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Fbxo32 |
F-box protein 32 |
increases expression multiple interactions |
ISO |
Palmitic Acid results in increased expression of FBXO32 mRNA Quercetin inhibits the reaction [Palmitic Acid results in increased expression of FBXO32 mRNA] |
CTD |
PMID:25614714 |
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NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436
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G |
Fbxw9 |
F-box and WD repeat domain containing 9 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of FBXW9 protein |
CTD |
PMID:28073184 |
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NCBI chr19:23,090,534...23,097,439
Ensembl chr19:23,090,534...23,097,439
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G |
Fgf2 |
fibroblast growth factor 2 |
multiple interactions |
ISO |
[osteum co-treated with Palmitic Acid] results in increased expression of FGF2 mRNA; MRI-1867 inhibits the reaction [[osteum co-treated with Palmitic Acid] results in increased expression of FGF2 mRNA] |
CTD |
PMID:31454063 |
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NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
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G |
Fgf21 |
fibroblast growth factor 21 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FGF21 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of FGF21 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
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G |
Fis1 |
fission, mitochondrial 1 |
multiple interactions increases expression |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of FIS1 mRNA]; [Fructose co-treated with Palmitic Acid] results in increased expression of FIS1 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of FIS1 mRNA; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of FIS1 protein] Palmitic Acid results in increased expression of FIS1 protein carnosol inhibits the reaction [Palmitic Acid results in increased expression of FIS1 protein]; PRDX3 protein inhibits the reaction [Palmitic Acid results in increased expression of FIS1 protein]; PRDX3 protein promotes the reaction [carnosol inhibits the reaction [Palmitic Acid results in increased expression of FIS1 protein]] |
CTD |
PMID:32369900 PMID:32730863 PMID:34678374 |
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NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377
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G |
Fkbp15 |
FKBP prolyl isomerase family member 15 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of FKBP15 protein |
CTD |
PMID:28073184 |
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NCBI chr 5:75,750,786...75,815,038
Ensembl chr 5:75,750,787...75,814,990
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G |
Fkbp5 |
FKBP prolyl isomerase 5 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of FKBP5 protein |
CTD |
PMID:28073184 |
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NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
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G |
Flot1 |
flotillin 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FLOT1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978
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G |
Fosl2 |
FOS like 2, AP-1 transcription factor subunit |
increases expression multiple interactions |
ISO |
Palmitic Acid results in increased expression of FOSL2 mRNA Palmitic Acid inhibits the reaction [sodium arsenite results in increased expression of FOSL2 mRNA]; sodium arsenite inhibits the reaction [Palmitic Acid results in increased expression of FOSL2 mRNA] |
CTD |
PMID:34968464 |
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NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
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G |
Foxa1 |
forkhead box A1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of FOXA1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of FOXA1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
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G |
Foxl2 |
forkhead box L2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of FOXL2 mRNA; Palmitic Acid promotes the reaction [[sodium arsenite co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of FOXL2 mRNA]; sodium arsenite promotes the reaction [[Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of FOXL2 mRNA] |
CTD |
PMID:34968464 |
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NCBI chr 8:99,512,971...99,514,500
Ensembl chr 8:99,513,303...99,514,427
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G |
Foxo1 |
forkhead box O1 |
multiple interactions decreases expression decreases phosphorylation increases localization |
ISO EXP |
4-methylumbelliferone 8-carbaldehyde inhibits the reaction [Palmitic Acid results in decreased expression of FOXO1 mRNA]; 4-methylumbelliferone 8-carbaldehyde inhibits the reaction [Palmitic Acid results in decreased expression of FOXO1 protein]; 4-phenylbutyric acid inhibits the reaction [Palmitic Acid results in decreased expression of FOXO1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Palmitic Acid results in decreased expression of FOXO1 protein]; [GCG protein co-treated with candesartan] inhibits the reaction [Palmitic Acid results in decreased phosphorylation of FOXO1 protein]; [Oleic Acid co-treated with Palmitic Acid] results in decreased phosphorylation of FOXO1 protein; [Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of FOXO1 mRNA; [sodium arsenite co-treated with Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of FOXO1 mRNA; candesartan inhibits the reaction [Palmitic Acid results in decreased phosphorylation of FOXO1 protein]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NFE2L2 mRNA]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of TFAM mRNA]; GCG protein inhibits the reaction [Palmitic Acid results in decreased phosphorylation of FOXO1 protein]; GSK2656157 inhibits the reaction [Palmitic Acid results in decreased expression of FOXO1 mRNA]; Palmitic Acid inhibits the reaction [sodium arsenite results in increased expression of FOXO1 mRNA] Palmitic Acid results in decreased expression of FOXO1 mRNA; Palmitic Acid results in decreased expression of FOXO1 protein geniposide inhibits the reaction [Palmitic Acid results in decreased phosphorylation of FOXO1 protein]; resveratrol inhibits the reaction [Palmitic Acid results in increased localization of FOXO1 protein] |
CTD |
PMID:21255808 PMID:22819839 PMID:22968147 PMID:26847930 PMID:34968464 PMID:36030031 More...
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NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
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G |
Frs2 |
fibroblast growth factor receptor substrate 2 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of FRS2 protein |
CTD |
PMID:28073184 |
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NCBI chr 7:52,711,255...52,792,738
Ensembl chr 7:52,711,257...52,792,743
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G |
Fth1 |
ferritin heavy chain 1 |
increases expression multiple interactions |
ISO |
Palmitic Acid results in increased expression of FTH1 protein [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of FTH1 protein; ferric ammonium citrate promotes the reaction [Palmitic Acid results in increased expression of FTH1 protein]; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of FTH1 protein] |
CTD |
PMID:32283200 PMID:32976958 |
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NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
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G |
Fubp1 |
far upstream element binding protein 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of FUBP1 protein |
CTD |
PMID:28073184 |
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NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
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G |
Fxr2 |
FMR1 autosomal homolog 2 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of FXR2 protein |
CTD |
PMID:28073184 |
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NCBI chr10:54,350,577...54,370,964
Ensembl chr10:54,350,131...54,370,964
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G |
G3bp1 |
G3BP stress granule assembly factor 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of G3BP1 protein |
CTD |
PMID:28073184 |
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NCBI chr10:39,586,864...39,620,268
Ensembl chr10:39,586,864...39,620,268
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G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]] |
CTD |
PMID:26847930 |
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NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
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G |
Gcg |
glucagon |
multiple interactions |
ISO |
[GCG protein co-treated with candesartan] inhibits the reaction [Palmitic Acid results in decreased phosphorylation of FOXO1 protein]; [GCG protein co-treated with candesartan] inhibits the reaction [Palmitic Acid results in decreased phosphorylation of IRS2 protein]; GCG protein inhibits the reaction [Palmitic Acid results in decreased phosphorylation of FOXO1 protein]; GCG protein inhibits the reaction [Palmitic Acid results in decreased phosphorylation of IRS2 protein]; isosteviol inhibits the reaction [Palmitic Acid promotes the reaction [Glucose results in increased secretion of GCG protein]]; Palmitic Acid promotes the reaction [Glucose results in increased secretion of GCG protein] |
CTD |
PMID:21255808 PMID:22479612 |
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NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
increases expression |
EXP |
Palmitic Acid results in increased expression of GCLC mRNA |
CTD |
PMID:28027979 |
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NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Ggt1 |
gamma-glutamyltransferase 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of GGT1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
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G |
Gigyf1 |
GRB10 interacting GYF protein 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of GIGYF1 protein |
CTD |
PMID:28073184 |
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NCBI chr12:19,166,070...19,181,570
Ensembl chr12:19,166,088...19,175,023
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G |
Glcci1 |
glucocorticoid induced 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of GLCCI1 protein |
CTD |
PMID:28073184 |
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NCBI chr 4:36,307,956...36,635,614
Ensembl chr 4:36,307,903...36,635,612
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G |
Glrx |
glutaredoxin |
multiple interactions |
ISO |
GLRX protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] promotes the reaction [Glutathione binds to SIRT1 protein]]; GLRX protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased oxidation of and results in decreased activity of SIRT1 protein] |
CTD |
PMID:24451382 |
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NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
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G |
Gls |
glutaminase |
decreases oxidation |
ISO |
GLS protein results in decreased oxidation of Palmitic Acid |
CTD |
PMID:31040181 |
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NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
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G |
Glud1 |
glutamate dehydrogenase 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of GLUD1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
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G |
Golga4 |
golgin A4 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of GOLGA4 protein |
CTD |
PMID:28073184 |
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NCBI chr 8:118,208,200...118,285,003
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G |
Gosr1 |
golgi SNAP receptor complex member 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of GOSR1 protein |
CTD |
PMID:28073184 |
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NCBI chr10:61,570,499...61,607,287
Ensembl chr10:61,450,494...61,607,177 Ensembl chr10:61,450,494...61,607,177
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G |
Gpam |
glycerol-3-phosphate acyltransferase, mitochondrial |
increases expression |
ISO |
Palmitic Acid results in increased expression of GPAM mRNA |
CTD |
PMID:29414781 |
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NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
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G |
Gpatch8 |
G patch domain containing 8 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of GPATCH8 protein |
CTD |
PMID:28073184 |
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NCBI chr10:87,432,020...87,512,594
Ensembl chr10:87,433,266...87,512,419
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G |
Gpr173 |
G-protein coupled receptor 173 |
multiple interactions decreases expression |
ISO |
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Palmitic Acid results in decreased expression of GPR173 mRNA] |
CTD |
PMID:30716364 |
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NCBI chr X:21,446,261...21,471,119
Ensembl chr X:21,447,361...21,471,498
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
ISO |
[Cisplatin co-treated with Palmitic Acid] results in increased expression of GPT protein; [Palmitic Acid co-treated with Oleic Acid] results in increased activity of GPT protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased activity of GPT protein] |
CTD |
PMID:28073184 PMID:32976958 |
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NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Gpx1 |
glutathione peroxidase 1 |
decreases expression multiple interactions |
ISO |
Palmitic Acid results in decreased expression of GPX1 mRNA [Palmitic Acid co-treated with Arsenic] affects the expression of GPX1 mRNA; Rosiglitazone inhibits the reaction [Palmitic Acid results in decreased expression of GPX1 mRNA] |
CTD |
PMID:18155663 PMID:33736254 |
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NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Gpx2 |
glutathione peroxidase 2 |
increases expression |
EXP |
Palmitic Acid results in increased expression of GPX2 mRNA |
CTD |
PMID:28027979 |
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NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
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G |
Gpx4 |
glutathione peroxidase 4 |
increases expression multiple interactions |
EXP ISO |
Palmitic Acid results in increased expression of GPX4 mRNA [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein] |
CTD |
PMID:28027979 PMID:32976958 |
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NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
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G |
Gsk3a |
glycogen synthase kinase 3 alpha |
affects phosphorylation |
ISO |
Palmitic Acid affects the phosphorylation of GSK3A protein |
CTD |
PMID:28073184 |
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NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions increases phosphorylation |
ISO EXP |
Palmitic Acid inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of GSK3B protein] Palmitic Acid results in increased phosphorylation of GSK3B protein 4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; CYLD protein affects the reaction [Palmitic Acid results in increased phosphorylation of GSK3B protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]; PKF115-584 inhibits the reaction [CYLD protein affects the reaction [Palmitic Acid results in increased phosphorylation of GSK3B protein]] |
CTD |
PMID:25109277 PMID:30362509 PMID:34774660 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gsr |
glutathione-disulfide reductase |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] results in increased expression of GSR mRNA |
CTD |
PMID:33736254 |
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NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Gsta1 |
glutathione S-transferase alpha 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of GSTA1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
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G |
Gtf2i |
general transcription factor II I |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of GTF2I protein |
CTD |
PMID:28073184 |
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NCBI chr12:22,400,933...22,476,243
Ensembl chr12:22,401,431...22,476,243
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G |
Gtf3c1 |
general transcription factor IIIC subunit 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of GTF3C1 protein |
CTD |
PMID:28073184 |
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NCBI chr 1:180,203,995...180,270,201
Ensembl chr 1:180,203,995...180,270,201
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G |
Gtse1 |
G-2 and S-phase expressed 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of GTSE1 protein |
CTD |
PMID:28073184 |
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NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806
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G |
Gys1 |
glycogen synthase 1 |
multiple interactions |
ISO |
Palmitic Acid inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of GYS1 protein] |
CTD |
PMID:30362509 |
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NCBI chr 1:95,915,443...95,935,292
Ensembl chr 1:95,915,443...95,935,292
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G |
Hacd3 |
3-hydroxyacyl-CoA dehydratase 3 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of HACD3 protein |
CTD |
PMID:28073184 |
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NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507
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G |
Hal |
histidine ammonia lyase |
increases expression |
ISO |
Palmitic Acid results in increased expression of HAL mRNA |
CTD |
PMID:17658692 |
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NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
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G |
Hamp |
hepcidin antimicrobial peptide |
increases expression |
ISO |
Palmitic Acid results in increased expression of HAMP mRNA |
CTD |
PMID:17658692 |
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NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
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G |
Hbp1 |
HMG-box transcription factor 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of HBP1 protein |
CTD |
PMID:28073184 |
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NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787
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G |
Hdgf |
heparin binding growth factor |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of HDGF protein |
CTD |
PMID:28073184 |
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NCBI chr 2:173,370,147...173,379,756
Ensembl chr 2:173,370,465...173,379,747
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G |
Herc2 |
HECT and RLD domain containing E3 ubiquitin protein ligase 2 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of HERC2 protein |
CTD |
PMID:28073184 |
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NCBI chr 1:106,904,789...107,110,997
Ensembl chr 1:106,880,084...107,108,134
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HIF1A protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of HIF1A protein |
CTD |
PMID:30547786 |
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hilpda |
hypoxia inducible lipid droplet-associated |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HILPDA protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of HILPDA protein |
CTD |
PMID:30547786 |
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NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557
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G |
Hivep1 |
HIVEP zinc finger 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of HIVEP1 protein |
CTD |
PMID:28073184 |
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NCBI chr17:22,585,016...22,714,517
Ensembl chr17:22,585,016...22,711,956
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G |
Hmgb1 |
high mobility group box 1 |
increases secretion |
ISO |
Palmitic Acid results in increased secretion of HMGB1 protein |
CTD |
PMID:27689324 |
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NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
multiple interactions |
ISO |
[[Palmitic Acid co-treated with Oleic Acid] co-treated with IFNA2 protein alternative form] results in decreased expression of HMGCR protein |
CTD |
PMID:31299271 |
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NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
EXP ISO |
Palmitic Acid results in increased expression of HMOX1 mRNA Palmitic Acid results in increased expression of HMOX1 protein [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein] [amlexanox co-treated with Palmitic Acid] results in increased expression of HMOX1 mRNA |
CTD |
PMID:28027979 PMID:32905826 PMID:32976958 PMID:37117602 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hnf4a |
hepatocyte nuclear factor 4, alpha |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of HNF4A mRNA |
CTD |
PMID:30547786 |
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NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
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G |
Hnrnpk |
heterogeneous nuclear ribonucleoprotein K |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of HNRNPK protein |
CTD |
PMID:28073184 |
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NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997
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G |
Hnrnpul2 |
heterogeneous nuclear ribonucleoprotein U-like 2 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of HNRNPUL2 protein |
CTD |
PMID:28073184 |
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NCBI chr 1:205,713,431...205,725,553
Ensembl chr 1:205,711,886...205,725,553
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G |
Hsdl2 |
hydroxysteroid dehydrogenase like 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of HSDL2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of HSDL2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839
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G |
Hspa12a |
heat shock protein family A (Hsp70) member 12A |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] affects the expression of HSPA12A mRNA |
CTD |
PMID:33736254 |
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NCBI chr 1:257,935,642...258,096,602
Ensembl chr 1:257,935,644...258,096,846
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
increases expression multiple interactions |
EXP ISO |
Palmitic Acid results in increased expression of HSPA5 mRNA [7-hydroxycoumarin co-treated with Palmitic Acid] results in increased expression of HSPA5 mRNA; [Scopoletin co-treated with Palmitic Acid] results in increased expression of HSPA5 mRNA Palmitic Acid results in increased expression of HSPA5 protein [Palmitic Acid co-treated with Oleic Acid] affects the expression of HSPA5 mRNA 4-phenylbutyric acid inhibits the reaction [Palmitic Acid results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Palmitic Acid results in increased expression of HSPA5 protein]; obeticholic acid inhibits the reaction [Palmitic Acid results in increased expression of HSPA5 protein]; trigonelline inhibits the reaction [Palmitic Acid results in increased expression of HSPA5 protein] Palmitic Acid results in increased expression of HSPA5 mRNA; Palmitic Acid results in increased expression of HSPA5 protein |
CTD |
PMID:24349266 PMID:26655953 PMID:30208301 PMID:30547786 PMID:30738135 PMID:34979142 PMID:36030031 More...
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Htr2a |
5-hydroxytryptamine receptor 2A |
increases expression |
ISO |
Palmitic Acid results in increased expression of HTR2A protein |
CTD |
PMID:27133527 |
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NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
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G |
Htr2b |
5-hydroxytryptamine receptor 2B |
increases expression |
ISO |
Palmitic Acid results in increased expression of HTR2B protein |
CTD |
PMID:27133527 |
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NCBI chr 9:86,735,793...86,756,638
Ensembl chr 9:86,742,102...86,755,108
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G |
Huwe1 |
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of HUWE1 protein |
CTD |
PMID:28073184 |
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NCBI chr X:20,873,795...21,001,378
Ensembl chr X:20,873,795...21,001,262
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G |
Icam1 |
intercellular adhesion molecule 1 |
increases expression multiple interactions |
ISO |
Palmitic Acid results in increased expression of ICAM1 protein geraniol inhibits the reaction [Palmitic Acid results in increased expression of ICAM1 protein] |
CTD |
PMID:27107694 |
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Id3 |
inhibitor of DNA binding 3 |
decreases expression multiple interactions |
ISO |
Palmitic Acid results in decreased expression of ID3 mRNA [Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of ID3 mRNA; [sodium arsenite co-treated with Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of ID3 mRNA; Palmitic Acid inhibits the reaction [sodium arsenite results in increased expression of ID3 mRNA]; sodium arsenite inhibits the reaction [Palmitic Acid results in decreased expression of ID3 mRNA]; sodium arsenite promotes the reaction [[Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of ID3 mRNA] |
CTD |
PMID:34968464 |
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NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
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G |
Ifnb1 |
interferon beta 1 |
increases expression multiple interactions |
ISO |
Palmitic Acid results in increased expression of IFNB1 mRNA amlexanox inhibits the reaction [Palmitic Acid results in increased expression of IFNB1 mRNA]; pitavastatin inhibits the reaction [Palmitic Acid results in increased expression of IFNB1 mRNA]; Pravastatin inhibits the reaction [Palmitic Acid results in increased expression of IFNB1 mRNA] |
CTD |
PMID:18323514 PMID:32905826 |
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NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523
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G |
Igf2 |
insulin-like growth factor 2 |
increases expression |
ISO |
Palmitic Acid results in increased expression of IGF2 mRNA |
CTD |
PMID:17658692 |
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NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
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G |
Ikbke |
inhibitor of nuclear factor kappa B kinase subunit epsilon |
increases phosphorylation multiple interactions |
ISO |
Palmitic Acid results in increased phosphorylation of IKBKE protein amlexanox inhibits the reaction [Palmitic Acid results in increased phosphorylation of IKBKE protein] |
CTD |
PMID:32905826 |
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NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143
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G |
Il10 |
interleukin 10 |
affects expression decreases expression multiple interactions |
ISO |
Palmitic Acid affects the expression of IL10 mRNA Palmitic Acid results in decreased expression of IL10 protein amlexanox affects the reaction [Palmitic Acid affects the expression of IL10 mRNA]; amlexanox inhibits the reaction [Palmitic Acid results in decreased expression of IL10 protein]; mifobate affects the reaction [Palmitic Acid affects the expression of IL10 mRNA] |
CTD |
PMID:32905826 |
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NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il18 |
interleukin 18 |
multiple interactions increases cleavage increases expression |
EXP |
Lead promotes the reaction [Palmitic Acid results in increased cleavage of IL18 protein]; Lead promotes the reaction [Palmitic Acid results in increased expression of IL18 protein]; Palmitic Acid promotes the reaction [Lead results in increased cleavage of IL18 protein]; Palmitic Acid results in increased expression of and results in increased secretion of IL18 protein; SRT1720 inhibits the reaction [Lead promotes the reaction [Palmitic Acid results in increased expression of IL18 protein]]; STING1 protein promotes the reaction [Palmitic Acid results in increased secretion of IL18 protein] Palmitic Acid results in increased expression of IL18 mRNA; Palmitic Acid results in increased expression of IL18 protein |
CTD |
PMID:35235096 PMID:37244597 |
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NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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G |
Il1a |
interleukin 1 alpha |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] results in increased expression of IL1A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of IL1A mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of IL1A mRNA |
CTD |
PMID:30547786 PMID:33736254 |
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NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression increases secretion |
EXP ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein; [Palmitic Acid co-treated with Sincalide] results in increased expression of IL1B mRNA; [Palmitic Acid co-treated with Sincalide] results in increased expression of IL1B protein; Palmitic Acid results in increased expression of and results in increased secretion of IL1B protein; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein]; Quercetin inhibits the reaction [[Sincalide co-treated with Palmitic Acid] results in increased expression of IL1B protein]; STING1 protein promotes the reaction [Palmitic Acid results in increased expression of and results in increased secretion of IL1B protein] Palmitic Acid results in increased expression of IL1B mRNA (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of PPARG mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of PPARA mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CCL2 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CCL5 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CXCL5 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NFKB1 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of PPARD mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of RELA mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein; Bezafibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Bezafibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Bezafibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Bezafibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; GW 506033X inhibits the reaction [Palmitic Acid results in increased expression of IL1B mRNA]; GW 506033X inhibits the reaction [Palmitic Acid results in increased expression of IL1B protein]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein] Palmitic Acid results in increased expression of IL1B mRNA; Palmitic Acid results in increased expression of IL1B protein Palmitic Acid results in increased secretion of IL1B protein 4-(4-fluorophenyl)sulfonyl-5-methylthio-2-phenyloxazole analog inhibits the reaction [[Palmitic Acid co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein]; 4-(4-fluorophenyl)sulfonyl-5-methylthio-2-phenyloxazole inhibits the reaction [[Palmitic Acid co-treated with Lipopolysaccharides] results in increased expression of and results in increased cleavage of IL1B protein]; 4-(4-fluorophenyl)sulfonyl-5-methylthio-2-phenyloxazole inhibits the reaction [[Palmitic Acid co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein]; [Palmitic Acid co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL1B protein; [Palmitic Acid co-treated with Lipopolysaccharides] results in increased expression of and results in increased cleavage of IL1B protein; [Palmitic Acid co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein; amlexanox inhibits the reaction [Palmitic Acid results in increased expression of IL1B mRNA]; amlexanox inhibits the reaction [Palmitic Acid results in increased secretion of IL1B protein]; baicalin inhibits the reaction [Palmitic Acid results in increased secretion of IL1B protein]; CA 074 methyl ester inhibits the reaction [Palmitic Acid results in increased expression of IL1B protein]; NLRP3 inhibits the reaction [Palmitic Acid results in increased expression of IL1B protein]; Silymarin inhibits the reaction [[Palmitic Acid co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL1B protein]; ursodoxicoltaurine inhibits the reaction [Palmitic Acid results in increased secretion of IL1B protein] |
CTD |
PMID:26190035 PMID:26873426 PMID:27689324 PMID:29031535 PMID:29650965 PMID:29753610 PMID:30794626 PMID:32613381 PMID:32905826 PMID:35235096 More...
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
increases expression affects expression increases secretion multiple interactions |
ISO EXP |
Palmitic Acid results in increased expression of IL6 mRNA Palmitic Acid affects the expression of IL6 mRNA Palmitic Acid results in increased secretion of IL6 protein 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]; [Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein; [Palmitic Acid co-treated with Sincalide] results in increased expression of IL6 mRNA; [Palmitic Acid co-treated with Sincalide] results in increased expression of IL6 protein; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]; AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; coomassie Brilliant Blue inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; coomassie Brilliant Blue inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; imoxin inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; Metformin inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; parthenolide inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [[Sincalide co-treated with Palmitic Acid] results in increased expression of IL6 protein]; Resveratrol inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; Resveratrol inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; Resveratrol inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; Salicylic Acid inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; SB 203580 inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; SB 203580 inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]] 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid results in increased secretion of IL6 protein]; [Palmitic Acid co-treated with Arsenic] affects the expression of IL6 mRNA; [Palmitic Acid co-treated with Thioacetamide] results in increased secretion of IL6 protein; tin protoporphyrin IX inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid results in increased secretion of IL6 protein]] [Palmitic Acid co-treated with Ethanol] results in increased expression of IL6 mRNA; [Palmitic Acid co-treated with Ethanol] results in increased secretion of IL6 protein; amlexanox inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; amlexanox inhibits the reaction [Palmitic Acid results in increased secretion of IL6 protein]; baicalin inhibits the reaction [Palmitic Acid results in increased secretion of IL6 protein]; pitavastatin inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; Pravastatin inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; ursodoxicoltaurine inhibits the reaction [Palmitic Acid results in increased secretion of IL6 protein] |
CTD |
PMID:18323514 PMID:25108154 PMID:25348860 PMID:25815690 PMID:26873426 PMID:29031535 PMID:30259999 PMID:30625377 PMID:32905826 PMID:33736254 PMID:37271273 More...
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Ins1 |
insulin 1 |
multiple interactions decreases expression increases secretion |
ISO EXP |
[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]; [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; [Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CEBPA mRNA; [Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of FOXL2 mRNA; [Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of FOXO1 mRNA; [Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of LEP mRNA; [Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of NFYC mRNA; [Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of SIRT1 mRNA; [Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of TFAP2B mRNA; [Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased secretion of LEP protein; [Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of ID3 mRNA; [sodium arsenite co-treated with Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of ADIPOQ mRNA; [sodium arsenite co-treated with Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of ADIPOQ protein; [sodium arsenite co-treated with Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of and results in decreased secretion of LEP protein; [sodium arsenite co-treated with Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of FOXO1 mRNA; [sodium arsenite co-treated with Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of LEP mRNA; [sodium arsenite co-treated with Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of NFYC mRNA; [sodium arsenite co-treated with Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of PPARG mRNA; [sodium arsenite co-treated with Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of ID3 mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]]; isosteviol inhibits the reaction [Palmitic Acid inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; Palmitic Acid inhibits the reaction [[sodium arsenite co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of TFAP2B mRNA]; Palmitic Acid inhibits the reaction [[sodium arsenite co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased secretion of ADIPOQ protein]; Palmitic Acid inhibits the reaction [Glucose results in increased secretion of INS1 protein]; Palmitic Acid promotes the reaction [[sodium arsenite co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CEBPA mRNA]; Palmitic Acid promotes the reaction [[sodium arsenite co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of FOXL2 mRNA]; Palmitic Acid promotes the reaction [[sodium arsenite co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of SIRT1 mRNA]; sodium arsenite promotes the reaction [[Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CEBPA mRNA]; sodium arsenite promotes the reaction [[Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of FOXL2 mRNA]; sodium arsenite promotes the reaction [[Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of LEP mRNA]; sodium arsenite promotes the reaction [[Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of SIRT1 mRNA]; sodium arsenite promotes the reaction [[Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of ID3 mRNA] Palmitic Acid results in decreased expression of INS1 protein 4-phenylbutyric acid inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; bafilomycin A1 promotes the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; NCOA4 protein affects the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; NCOA4 protein inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]; Sirolimus inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; STF 083010 inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; Thapsigargin inhibits the reaction [ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]]; Thapsigargin inhibits the reaction [NCOA4 protein inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]] Exenatide inhibits the reaction [Palmitic Acid inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; Palmitic Acid inhibits the reaction [Glucose results in increased secretion of INS1 protein]; Palmitic Acid inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]; Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Palmitic Acid promotes the reaction [Glucose results in increased secretion of INS1 protein]; Quercetin inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]] Palmitic Acid results in increased secretion of INS1 protein |
CTD |
PMID:22479612 PMID:22713545 PMID:24349266 PMID:26847930 PMID:27939242 PMID:28027979 PMID:32283200 PMID:34968464 More...
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Ins2 |
insulin 2 |
multiple interactions decreases expression |
ISO EXP |
(R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Rosiglitazone inhibits the reaction [Palmitic Acid results in decreased expression of INS protein]]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of NOS3 protein]]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]]; 4-phenylbutyric acid inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of PPARG mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of PPARA mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CCL2 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CCL5 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CXCL5 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NFKB1 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of PPARD mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of RELA mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein; Bezafibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Bezafibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Bezafibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Bezafibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of NOS3 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Rosiglitazone inhibits the reaction [Palmitic Acid results in decreased expression of INS protein]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; STF 083010 inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; tin protoporphyrin IX inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]]]; tin protoporphyrin IX inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of NOS3 protein]]]; tin protoporphyrin IX inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]]] 4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein affects the localization of SLC2A4 protein]]; 4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; 4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; 4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; 4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of MAPK8 protein]]; 4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of MAPK9 protein]]; 4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; 4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]]; 4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of TBC1D4 protein]]; [Palmitic Acid co-treated with sodium bisulfide] inhibits the reaction [INS protein results in increased phosphorylation of RPS6KB1 protein]; Palmitic Acid inhibits the reaction [INS protein affects the localization of SLC2A4 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of MAPK8 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of MAPK9 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of TBC1D4 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased uptake of Glucose] [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of Palmitic Acid analog; [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased abundance of Palmitic Acid analog; Palmitic Acid inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form] |
CTD |
PMID:18155663 PMID:22558381 PMID:25109277 PMID:25815690 PMID:26820058 PMID:32283200 PMID:32613381 PMID:35577173 More...
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NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Insr |
insulin receptor |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] results in increased expression of INSR mRNA |
CTD |
PMID:33736254 |
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NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
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G |
Irf3 |
interferon regulatory factor 3 |
increases phosphorylation multiple interactions |
ISO EXP |
Palmitic Acid results in increased phosphorylation of IRF3 protein amlexanox inhibits the reaction [Palmitic Acid results in increased phosphorylation of IRF3 protein]; pitavastatin inhibits the reaction [Palmitic Acid results in increased phosphorylation of IRF3 protein]; Pravastatin inhibits the reaction [Palmitic Acid results in increased phosphorylation of IRF3 protein] |
CTD |
PMID:18323514 PMID:32905826 PMID:35235096 |
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NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
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G |
Irf4 |
interferon regulatory factor 4 |
increases expression |
ISO |
Palmitic Acid results in increased expression of IRF4 mRNA |
CTD |
PMID:32347412 |
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NCBI chr17:33,721,800...33,742,570
Ensembl chr17:33,721,811...33,740,070
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G |
Irs1 |
insulin receptor substrate 1 |
multiple interactions |
ISO EXP |
3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]]; Palmitic Acid inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of IRS1 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]; tin protoporphyrin IX inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]]] 4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein] |
CTD |
PMID:25109277 PMID:25815690 PMID:30362509 |
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NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
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G |
Irs2 |
insulin receptor substrate 2 |
multiple interactions decreases phosphorylation |
ISO |
[GCG protein co-treated with candesartan] inhibits the reaction [Palmitic Acid results in decreased phosphorylation of IRS2 protein]; candesartan inhibits the reaction [Palmitic Acid results in decreased phosphorylation of IRS2 protein]; GCG protein inhibits the reaction [Palmitic Acid results in decreased phosphorylation of IRS2 protein] [Palmitic Acid co-treated with Arsenic] results in increased expression of IRS2 mRNA |
CTD |
PMID:21255808 PMID:33736254 |
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NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
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G |
Itgam |
integrin subunit alpha M |
increases expression |
ISO |
Palmitate increases expression of ITGAM protein on monocytes |
RGD |
PMID:22640955 |
RGD:329853771 |
NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
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G |
Itprid2 |
ITPR interacting domain containing 2 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of ITPRID2 protein |
CTD |
PMID:28073184 |
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NCBI chr 3:64,536,707...64,573,978
Ensembl chr 3:64,536,707...64,573,978
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G |
Itsn1 |
intersectin 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of ITSN1 protein |
CTD |
PMID:28073184 |
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NCBI chr11:30,978,590...31,160,645
Ensembl chr11:30,978,590...31,160,645
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G |
Iyd |
iodotyrosine deiodinase |
multiple interactions |
ISO |
Palmitic Acid inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] |
CTD |
PMID:33352258 |
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NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
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G |
Jak1 |
Janus kinase 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of JAK1 protein; [Palmitic Acid co-treated with Oleic Acid] affects the expression of JAK1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of JAK1 protein |
CTD |
PMID:30547786 |
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NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
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G |
Jak2 |
Janus kinase 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of JAK2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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G |
Jmjd1c |
jumonji domain containing 1C |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of JMJD1C protein |
CTD |
PMID:28073184 |
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NCBI chr20:21,332,147...21,494,220
Ensembl chr20:21,332,147...21,463,122
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G |
Jmjd6 |
jumonji domain containing 6, arginine demethylase and lysine hydroxylase |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of JMJD6 protein |
CTD |
PMID:28073184 |
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NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] results in increased expression of JUN mRNA |
CTD |
PMID:33736254 |
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Kat7 |
lysine acetyltransferase 7 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of KAT7 protein |
CTD |
PMID:28073184 |
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NCBI chr10:80,221,519...80,255,590
Ensembl chr10:80,221,524...80,255,567
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G |
Kctd12 |
potassium channel tetramerization domain containing 12 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of KCTD12 protein |
CTD |
PMID:28073184 |
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NCBI chr15:79,800,078...79,806,017
Ensembl chr15:79,801,191...79,806,282
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G |
Klf15 |
KLF transcription factor 15 |
decreases expression multiple interactions |
EXP |
Palmitic Acid results in decreased expression of KLF15 protein CXCL12 protein inhibits the reaction [Palmitic Acid results in decreased expression of KLF15 protein]; CXCR7 protein promotes the reaction [CXCL12 protein inhibits the reaction [Palmitic Acid results in decreased expression of KLF15 protein]]; KLF15 protein promotes the reaction [CXCL12 protein inhibits the reaction [Palmitic Acid results in increased expression of CCN2 protein]]; MAPK11 protein promotes the reaction [CXCL12 protein inhibits the reaction [Palmitic Acid results in decreased expression of KLF15 protein]] |
CTD |
PMID:34310909 |
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NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374
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G |
Krt8 |
keratin 8 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of KRT8 protein |
CTD |
PMID:28073184 |
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NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
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G |
Krt80 |
keratin 80 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of KRT80 protein |
CTD |
PMID:28073184 |
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NCBI chr 7:132,463,216...132,485,134
Ensembl chr 7:132,463,218...132,485,508
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G |
Lamb1 |
laminin subunit beta 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of LAMB1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of LAMB1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585
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G |
Lamtor1 |
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of LAMTOR1 protein |
CTD |
PMID:28073184 |
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NCBI chr 1:156,272,116...156,277,687
Ensembl chr 1:156,272,064...156,291,179
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G |
Larp1 |
La ribonucleoprotein 1, translational regulator |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of LARP1 protein |
CTD |
PMID:28073184 |
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NCBI chr10:42,191,378...42,246,361
Ensembl chr10:42,191,325...42,243,371
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G |
Lcat |
lecithin cholesterol acyltransferase |
decreases response to substance multiple interactions |
EXP |
C1QTNF9 protein results in decreased susceptibility to Palmitic Acid ATG5 protein promotes the reaction [C1QTNF9 protein inhibits the reaction [Palmitic Acid results in increased expression of CASP3 protein modified form]]; C1QTNF9 protein promotes the reaction [Palmitic Acid results in increased expression of MAP1LC3B protein modified form] |
CTD |
PMID:32278738 |
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NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
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G |
Ldlr |
low density lipoprotein receptor |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of LDLR mRNA |
CTD |
PMID:30547786 |
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NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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G |
Leo1 |
LEO1 homolog, Paf1/RNA polymerase II complex component |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of LEO1 protein |
CTD |
PMID:28073184 |
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NCBI chr 8:76,199,547...76,223,983
Ensembl chr 8:76,199,099...76,223,983
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G |
Lep |
leptin |
multiple interactions decreases expression |
ISO |
[Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of LEP mRNA; [Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased secretion of LEP protein; [Palmitic Acid co-treated with sodium arsenite] results in decreased expression of LEP mRNA; [Palmitic Acid co-treated with sodium arsenite] results in decreased expression of LEP protein; [sodium arsenite co-treated with Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of and results in decreased secretion of LEP protein; [sodium arsenite co-treated with Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of LEP mRNA; Palmitic Acid inhibits the reaction [sodium arsenite results in decreased secretion of LEP protein]; sodium arsenite promotes the reaction [[Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of LEP mRNA] Palmitic Acid results in decreased expression of LEP mRNA; Palmitic Acid results in decreased expression of LEP protein |
CTD |
PMID:34968464 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Lig1 |
DNA ligase 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of LIG1 protein |
CTD |
PMID:28073184 |
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NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413
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G |
Lima1 |
LIM domain and actin binding 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of LIMA1 protein |
CTD |
PMID:28073184 |
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NCBI chr 7:130,901,717...131,001,512
Ensembl chr 7:130,901,717...131,001,473
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G |
Limch1 |
LIM and calponin homology domains 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of LIMCH1 protein |
CTD |
PMID:28073184 |
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NCBI chr14:41,112,579...41,425,001
Ensembl chr14:41,114,803...41,425,191
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G |
Lipc |
lipase C, hepatic type |
multiple interactions decreases abundance |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of Palmitic Acid LIPC gene mutant form results in decreased abundance of Palmitic Acid |
CTD |
PMID:24777581 |
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NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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G |
Lipg |
lipase G, endothelial type |
multiple interactions |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of Palmitic Acid |
CTD |
PMID:24777581 |
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NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
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G |
Lmo7 |
LIM domain 7 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of LMO7 protein |
CTD |
PMID:28073184 |
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NCBI chr15:78,566,999...78,769,833
Ensembl chr15:78,567,023...78,769,783
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G |
Mafa |
MAF bZIP transcription factor A |
multiple interactions |
ISO |
Palmitic Acid inhibits the reaction [Glucose results in increased expression of MAFA mRNA] |
CTD |
PMID:22558381 |
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NCBI chr 7:107,432,292...107,435,084
Ensembl chr 7:107,433,605...107,434,690
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
affects localization increases lipidation increases expression multiple interactions |
ISO EXP |
Palmitic Acid affects the localization of MAP1LC3B protein Palmitic Acid results in increased lipidation of MAP1LC3B protein Palmitic Acid results in increased expression of MAP1LC3B protein modified form C1QTNF9 protein promotes the reaction [Palmitic Acid results in increased expression of MAP1LC3B protein modified form] [Palmitic Acid co-treated with Oleic Acid] affects the expression of MAP1LC3B mRNA |
CTD |
PMID:30208301 PMID:30547786 PMID:32278738 PMID:34774660 |
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NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
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G |
Map3k5 |
mitogen-activated protein kinase kinase kinase 5 |
multiple interactions increases expression |
ISO |
carnosol inhibits the reaction [Palmitic Acid results in increased expression of MAP3K5 protein]; PRDX3 protein inhibits the reaction [Palmitic Acid results in increased expression of MAP3K5 protein]; PRDX3 protein promotes the reaction [carnosol inhibits the reaction [Palmitic Acid results in increased expression of MAP3K5 protein]] |
CTD |
PMID:34678374 |
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NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
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G |
Map3k7 |
mitogen activated protein kinase kinase kinase 7 |
increases phosphorylation |
EXP |
Palmitate increases phosphorylation of Map3k7 protein in neonatal ventricular cardiomyocytes |
RGD |
PMID:29143862 |
RGD:155804300 |
NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
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G |
Map3k8 |
mitogen-activated protein kinase kinase kinase 8 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP3K8 mRNA |
CTD |
PMID:30547786 |
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NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216
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G |
Map4k4 |
mitogen-activated protein kinase kinase kinase kinase 4 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP4K4 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation |
EXP ISO |
4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; 7-hydroxycoumarin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK1 protein]; acetovanillone inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK1 protein]; CYBA mutant form inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK1 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Scopoletin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK1 protein] Quercetin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK1 protein] Docosahexaenoic Acids inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:24080574 PMID:24986865 PMID:25109277 PMID:25614714 PMID:34979142 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk11 |
mitogen-activated protein kinase 11 |
multiple interactions |
EXP |
MAPK11 protein promotes the reaction [CXCL12 protein inhibits the reaction [Palmitic Acid results in decreased expression of KLF15 protein]]; MAPK11 protein promotes the reaction [CXCL12 protein inhibits the reaction [Palmitic Acid results in increased expression of CCN2 protein]] |
CTD |
PMID:34310909 |
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NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395
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G |
Mapk14 |
mitogen activated protein kinase 14 |
multiple interactions increases phosphorylation |
ISO |
[Palmitic Acid co-treated with Arsenic] results in increased expression of MAPK14 mRNA; Capsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK14 protein] |
CTD |
PMID:21745629 PMID:33736254 |
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NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
EXP ISO |
4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; 7-hydroxycoumarin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK3 protein]; acetovanillone inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK3 protein]; CYBA mutant form inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK3 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Scopoletin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK3 protein] Quercetin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK3 protein] Docosahexaenoic Acids inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:24080574 PMID:24986865 PMID:25109277 PMID:25614714 PMID:34979142 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions increases phosphorylation increases expression |
ISO EXP |
Capsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein] Palmitic Acid results in increased expression of MAPK8 mRNA 4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of MAPK8 protein]]; 7-hydroxycoumarin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of MAPK8 mRNA]; imoxin inhibits the reaction [Palmitic Acid results in increased expression of and results in increased phosphorylation of MAPK8 protein]; imoxin inhibits the reaction [Palmitic Acid results in increased expression of MAPK8 mRNA]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of MAPK8 protein]; Palmitic Acid results in increased expression of and results in increased phosphorylation of MAPK8 protein; parthenolide inhibits the reaction [Palmitic Acid results in increased expression of MAPK8 mRNA]; pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased expression of MAPK8 mRNA]; pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]; Scopoletin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein] carnosol inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]; Chromium inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]; PRDX3 protein inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]; PRDX3 protein promotes the reaction [carnosol inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]] |
CTD |
PMID:21134603 PMID:21745629 PMID:25109277 PMID:30259999 PMID:34678374 PMID:34979142 More...
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NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Mapk9 |
mitogen-activated protein kinase 9 |
multiple interactions increases phosphorylation |
ISO EXP |
Capsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK9 protein] 4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of MAPK9 protein]]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of MAPK9 protein] carnosol inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK9 protein]; Chromium inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK9 protein]; PRDX3 protein inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK9 protein]; PRDX3 protein promotes the reaction [carnosol inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK9 protein]] |
CTD |
PMID:21134603 PMID:21745629 PMID:25109277 PMID:34678374 |
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NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
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G |
Marcks |
myristoylated alanine rich protein kinase C substrate |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of MARCKS protein |
CTD |
PMID:28073184 |
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NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
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G |
Mdc1 |
mediator of DNA damage checkpoint 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of MDC1 protein |
CTD |
PMID:28073184 |
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NCBI chr20:2,893,693...2,912,394
Ensembl chr20:2,895,505...2,910,240
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G |
Mdn1 |
midasin AAA ATPase 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of MDN1 protein |
CTD |
PMID:28073184 |
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NCBI chr 5:47,055,435...47,190,426
Ensembl chr 5:47,055,447...47,186,332
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G |
Me1 |
malic enzyme 1 |
increases expression |
ISO |
Palmitic Acid results in increased expression of ME1 mRNA |
CTD |
PMID:29414781 |
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NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
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G |
Med24 |
mediator complex subunit 24 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of MED24 protein |
CTD |
PMID:28073184 |
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NCBI chr10:83,664,609...83,702,315
Ensembl chr10:83,664,609...83,690,123
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G |
Met |
MET proto-oncogene, receptor tyrosine kinase |
multiple interactions |
ISO |
Palmitic Acid inhibits the reaction [Quercetin results in decreased expression of MET protein] |
CTD |
PMID:25971889 |
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NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
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G |
Mfap1a |
microfibrillar-associated protein 1A |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of MFAP1 protein |
CTD |
PMID:28073184 |
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NCBI chr 3:108,440,163...108,456,744
Ensembl chr 3:108,438,845...108,456,750
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G |
Mff |
mitochondrial fission factor |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of MFF mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of MFF mRNA |
CTD |
PMID:32369900 |
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NCBI chr 9:84,007,798...84,036,039
Ensembl chr 9:84,007,798...84,036,039
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G |
Mfn1 |
mitofusin 1 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of MFN1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of MFN1 mRNA |
CTD |
PMID:32369900 |
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NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
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G |
Mfn2 |
mitofusin 2 |
multiple interactions decreases expression |
ISO |
[Fructose co-treated with Palmitic Acid] results in decreased expression of MFN2 protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of MFN2 protein] carnosol inhibits the reaction [Palmitic Acid results in decreased expression of MFN2 protein]; PRDX3 protein inhibits the reaction [Palmitic Acid results in decreased expression of MFN2 protein]; PRDX3 protein promotes the reaction [carnosol inhibits the reaction [Palmitic Acid results in decreased expression of MFN2 protein]] |
CTD |
PMID:32730863 PMID:34678374 |
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NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
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G |
Mgat1 |
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
multiple interactions increases expression |
ISO |
7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased expression of MGAT1 mRNA] |
CTD |
PMID:29414781 |
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NCBI chr10:33,563,642...33,582,718
Ensembl chr10:33,561,388...33,591,503
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G |
Mgll |
monoglyceride lipase |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid] affects the reaction [Chlorpyrifos results in decreased activity of MGLL protein] |
CTD |
PMID:35151815 |
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NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179
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G |
Mief1 |
mitochondrial elongation factor 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of MIEF1 protein |
CTD |
PMID:28073184 |
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NCBI chr 7:111,786,630...111,802,220
Ensembl chr 7:111,786,709...111,802,220
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G |
Mir141 |
microRNA 141 |
increases expression multiple interactions |
EXP |
Palmitic Acid results in increased expression of MIR141 mRNA 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in decreased expression of BCL2 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in increased expression of BAX protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in increased expression of CASP3 protein modified form]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in increased expression of CASP9 protein modified form]]; [Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in decreased expression of BCL2 protein]; [Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in increased expression of BAX protein]; [Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in increased expression of CASP3 protein modified form]; [Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in increased expression of CASP9 protein modified form]; MIR141 mRNA promotes the reaction [Palmitic Acid results in decreased expression of BCL2 protein]; MIR141 mRNA promotes the reaction [Palmitic Acid results in decreased expression of NOTCH1 protein modified form]; MIR141 mRNA promotes the reaction [Palmitic Acid results in decreased expression of NOTCH1 protein]; MIR141 mRNA promotes the reaction [Palmitic Acid results in decreased expression of PSEN1 mRNA]; MIR141 mRNA promotes the reaction [Palmitic Acid results in decreased expression of PSEN1 protein]; MIR141 mRNA promotes the reaction [Palmitic Acid results in increased expression of BAX protein]; MIR141 mRNA promotes the reaction [Palmitic Acid results in increased expression of CASP3 protein modified form]; MIR141 mRNA promotes the reaction [Palmitic Acid results in increased expression of CASP9 protein modified form]; MIR141 mRNA promotes the reaction [Palmitic Acid results in increased expression of PTEN protein]; N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [[Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in decreased expression of BCL2 protein]]; N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [[Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in increased expression of BAX protein]]; N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [[Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in increased expression of CASP3 protein modified form]]; N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [[Polyribonucleotides results in decreased expression of MIR141 mRNA] inhibits the reaction [Palmitic Acid results in increased expression of CASP9 protein modified form]] |
CTD |
PMID:34897970 |
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NCBI chr 4:157,523,239...157,523,332
Ensembl chr 4:157,523,239...157,523,332
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G |
Misp |
mitotic spindle positioning |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of MISP protein |
CTD |
PMID:28073184 |
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NCBI chr 7:9,870,390...9,886,541
Ensembl chr 7:9,870,444...9,886,541
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G |
Mki67 |
marker of proliferation Ki-67 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of MKI67 protein |
CTD |
PMID:28073184 |
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NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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G |
Mmp1 |
matrix metallopeptidase 1 |
increases expression multiple interactions |
ISO |
Palmitic Acid results in increased expression of MMP1B mRNA [Palmitic Acid co-treated with Ethanol] results in increased expression of MMP1B mRNA |
CTD |
PMID:37271273 |
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NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MMP2 mRNA |
CTD |
PMID:26187275 |
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NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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G |
Mpdz |
multiple PDZ domain crumbs cell polarity complex component |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of MPDZ protein |
CTD |
PMID:28073184 |
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NCBI chr 5:95,766,112...95,920,531
Ensembl chr 5:95,766,118...95,920,499
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G |
Mrtfa |
myocardin related transcription factor A |
affects localization multiple interactions |
ISO |
Palmitic Acid affects the localization of MRTFA protein CCG 1423 inhibits the reaction [Palmitic Acid affects the localization of MRTFA protein] |
CTD |
PMID:21393865 |
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NCBI chr 7:112,544,305...112,714,418
Ensembl chr 7:112,544,312...112,714,418
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G |
Msl3 |
MSL complex subunit 3 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of MSL3 protein |
CTD |
PMID:28073184 |
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NCBI chr X:25,638,029...25,655,698
Ensembl chr X:25,637,804...25,655,697
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G |
Mt1-ps3 |
metallothionein 1, pseudogene 3 |
decreases expression |
ISO |
Palmitic Acid results in decreased expression of MT1E mRNA |
CTD |
PMID:17658692 |
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NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135
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G |
Mt2A |
metallothionein 2A |
decreases expression multiple interactions |
ISO EXP |
Palmitic Acid results in decreased expression of MT2A mRNA [Palmitic Acid co-treated with Arsenic] results in increased expression of MT2A mRNA [Oleic Acid co-treated with Palmitic Acid] results in increased expression of MT2A mRNA |
CTD |
PMID:17658692 PMID:26854922 PMID:33736254 |
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NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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G |
Mta3 |
metastasis associated 1 family, member 3 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of MTA3 protein |
CTD |
PMID:28073184 |
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NCBI chr 6:10,867,028...10,987,221
Ensembl chr 6:10,867,011...10,986,883
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G |
Mtbp |
MDM2 binding protein |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of MTBP protein |
CTD |
PMID:28073184 |
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NCBI chr 7:86,973,215...87,055,775
Ensembl chr 7:86,973,069...87,050,827
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G |
Mtdh |
metadherin |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of MTDH protein |
CTD |
PMID:28073184 |
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NCBI chr 7:65,306,464...65,365,647
Ensembl chr 7:65,306,400...65,364,413
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G |
Mtor |
mechanistic target of rapamycin kinase |
multiple interactions increases phosphorylation increases activity |
ISO |
sarpogrelate inhibits the reaction [Palmitic Acid results in increased activity of MTOR protein]; Sirolimus inhibits the reaction [Palmitic Acid results in increased activity of MTOR protein] trigonelline inhibits the reaction [Palmitic Acid results in increased phosphorylation of MTOR protein] |
CTD |
PMID:27133527 PMID:30208301 |
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NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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G |
Mttp |
microsomal triglyceride transfer protein |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MTTP mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MTTP mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of MTTP mRNA; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MTTP mRNA] |
CTD |
PMID:30547786 PMID:36347319 |
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NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
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G |
Naip6 |
NLR family, apoptosis inhibitory protein 6 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] affects the expression of NAIP mRNA |
CTD |
PMID:33736254 |
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NCBI chr 2:31,507,423...31,559,098
Ensembl chr 2:31,507,424...31,570,542
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G |
Nbn |
nibrin |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of NBN protein |
CTD |
PMID:28073184 |
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NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150
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G |
Ncapd2 |
non-SMC condensin I complex, subunit D2 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of NCAPD2 protein |
CTD |
PMID:28073184 |
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NCBI chr 4:157,968,814...157,992,314
Ensembl chr 4:157,968,815...157,992,020
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G |
Ncf1 |
neutrophil cytosolic factor 1 |
multiple interactions increases expression |
EXP |
acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of NCF1 mRNA]; U 0126 inhibits the reaction [Palmitic Acid results in increased expression of NCF1 mRNA] |
CTD |
PMID:24080574 |
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NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
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G |
Ncf2 |
neutrophil cytosolic factor 2 |
increases expression multiple interactions |
EXP |
Palmitic Acid results in increased expression of NCF2 mRNA acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of NCF2 mRNA]; U 0126 inhibits the reaction [Palmitic Acid results in increased expression of NCF2 mRNA] |
CTD |
PMID:24080574 |
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NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277
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G |
Ncoa2 |
nuclear receptor coactivator 2 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of NCOA2 protein |
CTD |
PMID:28073184 |
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NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
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G |
Ncoa4 |
nuclear receptor coactivator 4 |
multiple interactions increases expression |
ISO |
Deferoxamine promotes the reaction [Palmitic Acid results in increased expression of NCOA4 protein]; ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased expression of NCOA4 protein]; NCOA4 protein affects the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; NCOA4 protein inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; Thapsigargin inhibits the reaction [NCOA4 protein inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]]; Wortmannin inhibits the reaction [Palmitic Acid results in increased expression of NCOA4 protein] |
CTD |
PMID:32283200 |
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NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,366,542...7,409,641 Ensembl chr16:7,366,542...7,409,641
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G |
Ncor1 |
nuclear receptor co-repressor 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of NCOR1 protein |
CTD |
PMID:28073184 |
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NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
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G |
Ndrg2 |
NDRG family member 2 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of NDRG2 protein |
CTD |
PMID:28073184 |
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NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626
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G |
Nelfe |
negative elongation factor complex member E |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of NELFE protein |
CTD |
PMID:28073184 |
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NCBI chr20:3,976,512...3,982,389
Ensembl chr20:3,976,518...3,982,355
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G |
Nexn |
nexilin (F actin binding protein) |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of NEXN protein |
CTD |
PMID:28073184 |
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NCBI chr 2:241,186,783...241,218,315
Ensembl chr 2:241,186,790...241,218,342
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G |
Nf1 |
neurofibromin 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of NF1 protein |
CTD |
PMID:28073184 |
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NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NFE2L2 mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NFE2L2 mRNA] [Fructose co-treated with Palmitic Acid] results in decreased expression of NFE2L2 protein; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of and affects the localization of NFE2L2 protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of NFE2L2 protein]; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of and affects the localization of NFE2L2 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein] |
CTD |
PMID:26847930 PMID:32730863 PMID:32976958 |
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NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfil3 |
nuclear factor, interleukin 3 regulated |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of NFIL3 protein |
CTD |
PMID:28073184 |
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NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions increases expression |
EXP ISO |
Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of NFKB1 mRNA]; imoxin inhibits the reaction [Palmitic Acid results in increased expression of NFKB1 mRNA]; parthenolide inhibits the reaction [Palmitic Acid results in increased expression of NFKB1 mRNA]; pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased expression of NFKB1 mRNA] [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NFKB1 mRNA |
CTD |
PMID:30259999 PMID:32613381 |
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NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkbia |
NFKB inhibitor alpha |
increases degradation multiple interactions decreases phosphorylation |
ISO EXP |
Palmitic Acid results in increased degradation of NFKBIA protein Quercetin inhibits the reaction [Palmitic Acid results in decreased phosphorylation of NFKBIA protein] [Palmitic Acid co-treated with Sincalide] results in increased degradation of NFKBIA protein; Quercetin inhibits the reaction [[Sincalide co-treated with Palmitic Acid] results in increased degradation of NFKBIA protein] |
CTD |
PMID:21687928 PMID:25614714 PMID:26873426 |
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NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nfkbib |
NFKB inhibitor beta |
multiple interactions |
EXP |
[Palmitic Acid co-treated with Sincalide] results in increased degradation of NFKBIB protein; Quercetin inhibits the reaction [[Sincalide co-treated with Palmitic Acid] results in increased degradation of NFKBIB protein] |
CTD |
PMID:26873426 |
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NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
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G |
Nfyc |
nuclear transcription factor Y subunit gamma |
multiple interactions |
ISO |
[Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of NFYC mRNA; [sodium arsenite co-treated with Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of NFYC mRNA |
CTD |
PMID:34968464 |
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NCBI chr 5:134,336,802...134,405,372
Ensembl chr 5:134,336,808...134,405,377
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions increases expression |
ISO EXP |
baicalin inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 protein]; NLRP3 inhibits the reaction [Palmitic Acid results in increased cleavage of CASP1 protein]; NLRP3 inhibits the reaction [Palmitic Acid results in increased expression of IL1B protein]; ursodoxicoltaurine inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 protein] Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 mRNA]; imoxin inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 mRNA]; Lead promotes the reaction [Palmitic Acid results in increased expression of NLRP3 protein]; Palmitic Acid promotes the reaction [Lead results in increased expression of NLRP3 protein]; parthenolide inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 mRNA]; pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 mRNA]; SRT1720 inhibits the reaction [Lead promotes the reaction [Palmitic Acid results in increased expression of NLRP3 protein]]; SRT1720 inhibits the reaction [Palmitic Acid promotes the reaction [Lead results in increased expression of NLRP3 protein]]; SRT1720 inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 protein] Palmitic Acid results in increased expression of NLRP3 mRNA; Palmitic Acid results in increased expression of NLRP3 protein |
CTD |
PMID:27689324 PMID:29031535 PMID:30259999 PMID:37244597 |
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NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
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G |
Nol8 |
nucleolar protein 8 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of NOL8 protein |
CTD |
PMID:28073184 |
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NCBI chr17:14,990,394...15,013,784
Ensembl chr17:14,990,417...15,013,848
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G |
Nolc1 |
nucleolar and coiled-body phosphoprotein 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of NOLC1 protein |
CTD |
PMID:28073184 |
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NCBI chr 1:244,921,275...244,932,089
Ensembl chr 1:244,921,377...244,932,088
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G |
Nop56 |
NOP56 ribonucleoprotein |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of NOP56 protein |
CTD |
PMID:28073184 |
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NCBI chr 3:117,476,963...117,481,847
Ensembl chr 3:117,477,053...117,481,841
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G |
Nos2 |
nitric oxide synthase 2 |
increases expression multiple interactions |
ISO EXP |
Palmitic Acid results in increased expression of NOS2 mRNA Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; imoxin inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; Metformin inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; parthenolide inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; Quercetin inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; Resveratrol inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; Salicylic Acid inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA] amlexanox inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; amlexanox inhibits the reaction [Palmitic Acid results in increased expression of NOS2 protein]; mifobate inhibits the reaction [amlexanox inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]]; pitavastatin inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; Pravastatin inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA] Palmitic Acid results in increased expression of NOS2 mRNA; Palmitic Acid results in increased expression of NOS2 protein rosiglitazone inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA] |
CTD |
PMID:18155663 PMID:18323514 PMID:22713545 PMID:25108154 PMID:30259999 PMID:32905826 More...
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nos3 |
nitric oxide synthase 3 |
multiple interactions |
EXP ISO |
AICA ribonucleotide inhibits the reaction [Palmitic Acid inhibits the reaction [Acetylcholine results in increased phosphorylation of NOS3 protein]]; Metformin inhibits the reaction [Palmitic Acid inhibits the reaction [Acetylcholine results in increased phosphorylation of NOS3 protein]]; Palmitic Acid inhibits the reaction [Acetylcholine results in increased phosphorylation of NOS3 protein]; Resveratrol inhibits the reaction [Palmitic Acid inhibits the reaction [Acetylcholine results in increased phosphorylation of NOS3 protein]]; Salicylic Acid inhibits the reaction [Palmitic Acid inhibits the reaction [Acetylcholine results in increased phosphorylation of NOS3 protein]] 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of NOS3 protein]]; Agmatine inhibits the reaction [Palmitic Acid results in increased activity of and results in decreased phosphorylation of NOS3 protein]; dorsomorphin inhibits the reaction [Agmatine inhibits the reaction [Palmitic Acid results in increased activity of and results in decreased phosphorylation of NOS3 protein]]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of NOS3 protein]; Palmitic Acid results in increased activity of and results in decreased phosphorylation of NOS3 protein; tin protoporphyrin IX inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of NOS3 protein]]] |
CTD |
PMID:25108154 PMID:25815690 PMID:35747990 |
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NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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G |
Notch1 |
notch receptor 1 |
decreases expression multiple interactions |
EXP |
Palmitic Acid results in decreased expression of NOTCH1 protein; Palmitic Acid results in decreased expression of NOTCH1 protein modified form MIR141 mRNA promotes the reaction [Palmitic Acid results in decreased expression of NOTCH1 protein modified form]; MIR141 mRNA promotes the reaction [Palmitic Acid results in decreased expression of NOTCH1 protein] |
CTD |
PMID:34897970 |
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NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
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G |
Nox1 |
NADPH oxidase 1 |
increases expression multiple interactions |
EXP ISO |
Palmitic Acid results in increased expression of NOX1 mRNA geraniol inhibits the reaction [Palmitic Acid results in increased expression of NOX1 protein] |
CTD |
PMID:24080574 PMID:27107694 |
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NCBI chr X:97,279,058...97,332,291
Ensembl chr X:97,279,056...97,302,236
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G |
Noxa1 |
NADPH oxidase activator 1 |
multiple interactions increases expression |
EXP |
acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of NOXA1 mRNA]; U 0126 inhibits the reaction [Palmitic Acid results in increased expression of NOXA1 mRNA] |
CTD |
PMID:24080574 |
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NCBI chr 3:7,895,488...7,907,011
Ensembl chr 3:7,895,488...7,905,967
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G |
Noxo1 |
NADPH oxidase organizer 1 |
multiple interactions increases expression |
EXP |
acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of NOXO1 mRNA]; U 0126 inhibits the reaction [Palmitic Acid results in increased expression of NOXO1 mRNA] |
CTD |
PMID:24080574 |
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NCBI chr10:13,723,253...13,726,008
Ensembl chr10:13,721,473...13,726,061
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] results in increased expression of NQO1 mRNA |
CTD |
PMID:33736254 |
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NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Nr1h2 |
nuclear receptor subfamily 1, group H, member 2 |
decreases expression multiple interactions |
ISO |
Palmitic Acid results in decreased expression of NR1H2 mRNA; Palmitic Acid results in decreased expression of NR1H2 protein acanthoic acid inhibits the reaction [Palmitic Acid results in decreased expression of NR1H2 mRNA]; acanthoic acid inhibits the reaction [Palmitic Acid results in decreased expression of NR1H2 protein]; GW 3965 inhibits the reaction [Palmitic Acid results in decreased expression of NR1H2 mRNA]; GW 3965 inhibits the reaction [Palmitic Acid results in decreased expression of NR1H2 protein]; morroniside inhibits the reaction [Palmitic Acid results in decreased expression of NR1H2 mRNA]; morroniside inhibits the reaction [Palmitic Acid results in decreased expression of NR1H2 protein]; pregna-4,17-diene-3,16-dione promotes the reaction [Palmitic Acid results in decreased expression of NR1H2 mRNA] |
CTD |
PMID:31421115 PMID:34485530 |
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NCBI chr 1:95,041,967...95,047,358
Ensembl chr 1:95,041,967...95,047,377
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G |
Nr1h3 |
nuclear receptor subfamily 1, group H, member 3 |
multiple interactions decreases expression |
EXP ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of NR1H3 mRNA acanthoic acid inhibits the reaction [Palmitic Acid results in decreased expression of NR1H3 mRNA]; acanthoic acid inhibits the reaction [Palmitic Acid results in decreased expression of NR1H3 protein]; GW 3965 inhibits the reaction [Palmitic Acid results in decreased expression of NR1H3 mRNA]; GW 3965 inhibits the reaction [Palmitic Acid results in decreased expression of NR1H3 protein] Palmitic Acid results in decreased expression of NR1H3 mRNA; Palmitic Acid results in decreased expression of NR1H3 protein |
CTD |
PMID:26190035 PMID:31421115 |
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NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
multiple interactions decreases expression increases expression |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of NR1H4 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of NR1H4 mRNA; Permethrin inhibits the reaction [Palmitic Acid results in increased expression of NR1H4 mRNA] Palmitic Acid results in decreased expression of NR1H4 mRNA; Palmitic Acid results in decreased expression of NR1H4 protein acanthoic acid inhibits the reaction [Palmitic Acid results in decreased expression of NR1H4 mRNA]; acanthoic acid inhibits the reaction [Palmitic Acid results in decreased expression of NR1H4 protein]; GW 3965 inhibits the reaction [Palmitic Acid results in decreased expression of NR1H4 mRNA]; GW 3965 inhibits the reaction [Palmitic Acid results in decreased expression of NR1H4 protein]; pregna-4,17-diene-3,16-dione promotes the reaction [Palmitic Acid results in decreased expression of NR1H4 mRNA] |
CTD |
PMID:30547786 PMID:30738135 PMID:31421115 |
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NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of NR3C1 protein |
CTD |
PMID:28073184 |
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NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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G |
Nrf1 |
nuclear respiratory factor 1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA] |
CTD |
PMID:26847930 |
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NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
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G |
Ntsr1 |
neurotensin receptor 1 |
increases expression |
ISO |
Palmitic Acid results in increased expression of NTSR1 mRNA |
CTD |
PMID:32347412 |
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NCBI chr 3:167,606,215...167,656,371
Ensembl chr 3:167,606,215...167,656,377
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G |
Nucks1 |
nuclear casein kinase and cyclin-dependent kinase substrate 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of NUCKS1 protein |
CTD |
PMID:28073184 |
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NCBI chr13:43,345,091...43,374,316
Ensembl chr13:43,345,115...43,370,229
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G |
Nup153 |
nucleoporin 153 |
affects phosphorylation |
ISO |
Palmitic Acid affects the phosphorylation of NUP153 protein |
CTD |
PMID:28073184 |
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NCBI chr17:17,972,217...18,024,876
Ensembl chr17:17,972,217...18,024,876
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G |
Nup50 |
nucleoporin 50 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of NUP50 protein |
CTD |
PMID:28073184 |
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NCBI chr 7:116,047,960...116,065,231
Ensembl chr 7:116,048,021...116,066,905
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G |
Obi1 |
ORC ubiquitin ligase 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of OBI1 protein |
CTD |
PMID:28073184 |
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NCBI chr15:81,269,413...81,308,734
Ensembl chr15:81,269,416...81,308,734
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G |
Opa1 |
OPA1, mitochondrial dynamin like GTPase |
multiple interactions |
ISO |
[Fructose co-treated with Palmitic Acid] results in decreased expression of OPA1 protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of OPA1 protein] |
CTD |
PMID:32730863 |
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NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
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G |
Osbp |
oxysterol binding protein |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of OSBP protein |
CTD |
PMID:28073184 |
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NCBI chr 1:208,888,697...208,918,511
Ensembl chr 1:208,887,895...208,918,506
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G |
Oxr1 |
oxidation resistance 1 |
decreases phosphorylation multiple interactions |
ISO |
Palmitic Acid results in decreased phosphorylation of OXR1 protein [Palmitic Acid co-treated with Arsenic] results in increased expression of OXR1 mRNA |
CTD |
PMID:28073184 PMID:33736254 |
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NCBI chr 7:72,528,750...72,965,666
Ensembl chr 7:72,528,786...72,965,666
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G |
Oxsr1 |
oxidative stress responsive kinase 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] results in increased expression of OXSR1 mRNA |
CTD |
PMID:33736254 |
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NCBI chr 8:118,972,754...119,062,102
Ensembl chr 8:118,972,754...119,062,027
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G |
P2rx7 |
purinergic receptor P2X 7 |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 protein; Resveratrol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 mRNA]; Resveratrol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 protein] |
CTD |
PMID:25348860 |
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NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
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G |
Paics |
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of PAICS protein |
CTD |
PMID:28073184 |
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NCBI chr14:31,199,086...31,232,731
Ensembl chr14:31,173,541...31,232,635
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G |
Pak2 |
p21 (RAC1) activated kinase 2 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of PAK2 protein |
CTD |
PMID:28073184 |
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NCBI chr11:68,707,940...68,768,816
Ensembl chr11:68,707,969...68,768,816
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions increases expression increases cleavage |
ISO EXP |
carnosol inhibits the reaction [Palmitic Acid results in increased expression of PARP1 protein modified form]; PRDX3 protein inhibits the reaction [Palmitic Acid results in increased expression of PARP1 protein modified form]; PRDX3 protein promotes the reaction [carnosol inhibits the reaction [Palmitic Acid results in increased expression of PARP1 protein modified form]]; trigonelline inhibits the reaction [Palmitic Acid results in increased cleavage of PARP1 protein] Palmitic Acid results in increased expression of PARP1 mRNA; Palmitic Acid results in increased expression of PARP1 protein |
CTD |
PMID:19513971 PMID:30208301 PMID:34678374 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pck1 |
phosphoenolpyruvate carboxykinase 1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]] |
CTD |
PMID:26847930 |
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NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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G |
Pcnp |
PEST proteolytic signal containing nuclear protein |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of PCNP protein |
CTD |
PMID:28073184 |
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NCBI chr11:44,592,766...44,607,372
Ensembl chr11:44,592,742...44,607,348
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G |
Pcnt |
pericentrin |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of PCNT protein |
CTD |
PMID:28073184 |
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NCBI chr20:12,190,597...12,278,723
Ensembl chr20:12,191,648...12,278,710
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G |
Pdgfa |
platelet derived growth factor subunit A |
multiple interactions |
ISO |
[osteum co-treated with Palmitic Acid] results in increased expression of PDGFA mRNA; MRI-1867 inhibits the reaction [[osteum co-treated with Palmitic Acid] results in increased expression of PDGFA mRNA] |
CTD |
PMID:31454063 |
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NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
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G |
Pdk4 |
pyruvate dehydrogenase kinase 4 |
multiple interactions increases expression |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PDK4 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PDK4 protein Palmitic Acid results in increased expression of PDK4 mRNA |
CTD |
PMID:30547786 PMID:32347412 |
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NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
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G |
Pdx1 |
pancreatic and duodenal homeobox 1 |
decreases expression multiple interactions |
ISO EXP |
Palmitic Acid results in decreased expression of PDX1 mRNA 3-aminobenzamide inhibits the reaction [Palmitic Acid results in decreased expression of PDX1 protein]; geniposide inhibits the reaction [Palmitic Acid results in decreased expression of PDX1 protein] Palmitic Acid inhibits the reaction [Glucose affects the localization of PDX1 protein] Palmitic Acid inhibits the reaction [Glucose results in increased expression of PDX1 mRNA] |
CTD |
PMID:18155663 PMID:19513971 PMID:22558381 PMID:22819839 |
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NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064
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G |
Pebp1 |
phosphatidylethanolamine binding protein 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PEBP1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PEBP1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
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G |
Pex1 |
peroxisomal biogenesis factor 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of PEX1 protein |
CTD |
PMID:28073184 |
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NCBI chr 4:30,519,950...30,558,953
Ensembl chr 4:30,519,955...30,558,921
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G |
Pex11a |
peroxisomal biogenesis factor 11 alpha |
increases abundance |
ISO |
PEX11A gene mutant form results in increased abundance of Palmitic Acid |
CTD |
PMID:30585412 |
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NCBI chr 1:133,680,091...133,687,172
Ensembl chr 1:133,680,091...133,687,172
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G |
Pfkfb3 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of PFKFB3 protein |
CTD |
PMID:28073184 |
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NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125
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G |
Phldb2 |
pleckstrin homology-like domain, family B, member 2 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of PHLDB2 protein |
CTD |
PMID:28073184 |
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NCBI chr11:54,859,173...55,078,212
Ensembl chr11:54,859,135...55,078,467
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G |
Piezo1 |
piezo-type mechanosensitive ion channel component 1 |
increases phosphorylation increases expression |
ISO |
Palmitic Acid results in increased phosphorylation of PIEZO1 protein Palmitic Acid results in increased expression of PIEZO1 protein |
CTD |
PMID:28073184 PMID:37117602 |
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NCBI chr19:50,544,580...50,606,812
Ensembl chr19:50,544,582...50,606,501
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G |
Pik3c2a |
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of PIK3C2A mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 1:170,577,942...170,684,353
Ensembl chr 1:170,577,942...170,683,472
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G |
Pikfyve |
phosphoinositide kinase, FYVE-type zinc finger containing |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of PIKFYVE protein |
CTD |
PMID:28073184 |
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NCBI chr 9:66,563,747...66,657,873
Ensembl chr 9:66,563,727...66,657,868
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G |
Pink1 |
PTEN induced kinase 1 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of PINK1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of PINK1 mRNA |
CTD |
PMID:32369900 |
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NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
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G |
Pklr |
pyruvate kinase L/R |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PKLR mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PKLR mRNA |
CTD |
PMID:30547786 |
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NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
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G |
Pld1 |
phospholipase D1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PLD1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692
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G |
Plec |
plectin |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of PLEC protein |
CTD |
PMID:28073184 |
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NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467
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G |
Plin1 |
perilipin 1 |
multiple interactions increases expression |
ISO |
trigonelline inhibits the reaction [Palmitic Acid results in increased expression of PLIN1 protein] |
CTD |
PMID:30208301 |
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NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
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G |
Plin2 |
perilipin 2 |
multiple interactions |
ISO EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PLIN2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PLIN2 protein [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN2 mRNA |
CTD |
PMID:25048947 PMID:30547786 |
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NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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G |
Plin3 |
perilipin 3 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in increased expression of PLIN3 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 9:1,111,178...1,123,057
Ensembl chr 9:1,102,366...1,123,147
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G |
Plin5 |
perilipin 5 |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN5 mRNA; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN5 mRNA] |
CTD |
PMID:25048947 |
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NCBI chr 9:939,745...946,188
Ensembl chr 9:939,747...946,120
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G |
Pnkp |
polynucleotide kinase 3'-phosphatase |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of PNKP protein |
CTD |
PMID:28073184 |
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NCBI chr 1:95,341,465...95,346,921
Ensembl chr 1:95,341,620...95,346,920
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G |
Pnpla3 |
patatin-like phospholipase domain containing 3 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PNPLA3 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PNPLA3 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077
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G |
Pof1b |
POF1B, actin binding protein |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of POF1B protein |
CTD |
PMID:28073184 |
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NCBI chr X:77,683,128...77,749,827
Ensembl chr X:77,683,128...77,749,688
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions decreases expression increases expression affects abundance increases activity |
ISO EXP |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of PPARA mRNA; [Palmitic Acid co-treated with Arsenic] results in increased expression of PPARA mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PPARA mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PPARA mRNA; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein]; Ivermectin inhibits the reaction [Palmitic Acid results in increased expression of PPARA mRNA]; Palmitic Acid binds to and results in increased activity of PPARA protein; Permethrin inhibits the reaction [Palmitic Acid results in increased expression of PPARA mRNA] Palmitic Acid results in decreased expression of PPARA mRNA; Palmitic Acid results in decreased expression of PPARA protein [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARA mRNA; [tetrabromobisphenol A co-treated with Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; [Triiodothyronine co-treated with Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein] PPARA protein affects the abundance of Palmitic Acid [decabromobiphenyl ether co-treated with osteum co-treated with Palmitic Acid] results in increased expression of PPARA protein; [osteum co-treated with Palmitic Acid] results in increased expression of PPARA protein; amlexanox inhibits the reaction [Palmitic Acid results in decreased expression of PPARA mRNA]; amlexanox inhibits the reaction [Palmitic Acid results in decreased expression of PPARA protein]; amlexanox promotes the reaction [Palmitic Acid results in increased expression of PPARA protein]; Diethylhexyl Phthalate inhibits the reaction [PPARA protein affects the abundance of Palmitic Acid]; Palmitic Acid inhibits the reaction [obeticholic acid results in increased expression of PPARA mRNA]; PPARA protein promotes the reaction [[GW 7647 results in increased oxidation of Palmitic Acid] which results in increased abundance of Carbon Dioxide]; PPARA protein promotes the reaction [[GW 7647 results in increased oxidation of Palmitic Acid] which results in increased abundance of Fatty Acids metabolite] Palmitic Acid results in increased activity of PPARA protein Palmitic Acid results in increased expression of PPARA mRNA; Palmitic Acid results in increased expression of PPARA protein |
CTD |
PMID:10403814 PMID:18154422 PMID:21324916 PMID:23619606 PMID:25048947 PMID:26190035 PMID:26655953 PMID:26854922 PMID:30547786 PMID:30738135 PMID:32613381 PMID:32905826 PMID:33736254 PMID:34757160 PMID:36347319 More...
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Ppard |
peroxisome proliferator-activated receptor delta |
multiple interactions |
EXP ISO |
[Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased expression of PPARD mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARB mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARD mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARB mRNA]; tetrabromobisphenol A inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARD mRNA] [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of PPARD mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PPARD mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PPARD mRNA |
CTD |
PMID:25048947 PMID:26190035 PMID:26854922 PMID:30547786 PMID:32613381 |
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NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
increases expression multiple interactions decreases expression |
ISO EXP |
Palmitic Acid results in increased expression of PPARG mRNA; Palmitic Acid results in increased expression of PPARG protein [Palmitic Acid co-treated with Ethanol] results in increased expression of PPARG mRNA; [Palmitic Acid co-treated with sodium arsenite] results in decreased expression of PPARG mRNA; [sodium arsenite co-treated with Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of PPARG mRNA; trigonelline inhibits the reaction [Palmitic Acid results in increased expression of PPARG protein] [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of PPARG mRNA; ATG7 protein affects the reaction [trigonelline inhibits the reaction [Palmitic Acid results in increased expression of PPARG protein]]; trigonelline inhibits the reaction [Palmitic Acid results in increased expression of PPARG protein] [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of PPARG mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA; AICA ribonucleotide inhibits the reaction [Palmitic Acid results in decreased expression of PPARG mRNA]; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA]; Metformin inhibits the reaction [Palmitic Acid results in decreased expression of PPARG mRNA]; Resveratrol inhibits the reaction [Palmitic Acid results in decreased expression of PPARG mRNA]; Salicylic Acid inhibits the reaction [Palmitic Acid results in decreased expression of PPARG mRNA]; tetrabromobisphenol A inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA]; Triiodothyronine inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA] |
CTD |
PMID:18154422 PMID:25048947 PMID:25108154 PMID:26190035 PMID:26854922 PMID:30208301 PMID:32613381 PMID:34968464 PMID:37271273 More...
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
increases expression decreases expression multiple interactions |
EXP ISO |
Palmitic Acid results in increased expression of PPARGC1A mRNA Palmitic Acid results in decreased expression of PPARGC1A mRNA; Palmitic Acid results in decreased expression of PPARGC1A protein [Fructose co-treated with Palmitic Acid] results in decreased expression of PPARGC1A protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of PPARGC1A protein] [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA]; morroniside inhibits the reaction [Palmitic Acid results in decreased expression of PPARGC1A mRNA]; morroniside inhibits the reaction [Palmitic Acid results in decreased expression of PPARGC1A protein] |
CTD |
PMID:23056435 PMID:26847930 PMID:32730863 PMID:34485530 |
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NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Ppp1r12a |
protein phosphatase 1, regulatory subunit 12A |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of PPP1R12A protein |
CTD |
PMID:28073184 |
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NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425
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G |
Ppp1r2 |
protein phosphatase 1, regulatory (inhibitor) subunit 2 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of PPP1R2 protein |
CTD |
PMID:28073184 |
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NCBI chr11:69,472,676...69,494,468
Ensembl chr11:69,472,555...69,494,463
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G |
Prdx1 |
peroxiredoxin 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] results in increased expression of PRDX1 mRNA |
CTD |
PMID:33736254 |
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NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856
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G |
Prdx3 |
peroxiredoxin 3 |
multiple interactions decreases expression |
ISO |
carnosol inhibits the reaction [Palmitic Acid results in decreased expression of PRDX3 protein]; PRDX3 protein inhibits the reaction [Palmitic Acid results in decreased expression of MFN2 protein]; PRDX3 protein inhibits the reaction [Palmitic Acid results in increased cleavage of CASP3 protein]; PRDX3 protein inhibits the reaction [Palmitic Acid results in increased expression of BAX protein]; PRDX3 protein inhibits the reaction [Palmitic Acid results in increased expression of DNM1L protein]; PRDX3 protein inhibits the reaction [Palmitic Acid results in increased expression of FIS1 protein]; PRDX3 protein inhibits the reaction [Palmitic Acid results in increased expression of MAP3K5 protein]; PRDX3 protein inhibits the reaction [Palmitic Acid results in increased expression of PARP1 protein modified form]; PRDX3 protein inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]; PRDX3 protein inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK9 protein]; PRDX3 protein promotes the reaction [carnosol inhibits the reaction [Palmitic Acid results in decreased expression of BCL2 protein]]; PRDX3 protein promotes the reaction [carnosol inhibits the reaction [Palmitic Acid results in decreased expression of MFN2 protein]]; PRDX3 protein promotes the reaction [carnosol inhibits the reaction [Palmitic Acid results in increased expression of BAX protein]]; PRDX3 protein promotes the reaction [carnosol inhibits the reaction [Palmitic Acid results in increased expression of DNM1L protein]]; PRDX3 protein promotes the reaction [carnosol inhibits the reaction [Palmitic Acid results in increased expression of FIS1 protein]]; PRDX3 protein promotes the reaction [carnosol inhibits the reaction [Palmitic Acid results in increased expression of MAP3K5 protein]]; PRDX3 protein promotes the reaction [carnosol inhibits the reaction [Palmitic Acid results in increased expression of PARP1 protein modified form]]; PRDX3 protein promotes the reaction [carnosol inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]]; PRDX3 protein promotes the reaction [carnosol inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK9 protein]] |
CTD |
PMID:34678374 |
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NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
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G |
Prkaa1 |
protein kinase AMP-activated catalytic subunit alpha 1 |
multiple interactions increases oxidation |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PRKAA1 mRNA PRKAA1 protein results in increased oxidation of Palmitic Acid |
CTD |
PMID:30547786 PMID:31040181 |
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NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
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G |
Prkaa2 |
protein kinase AMP-activated catalytic subunit alpha 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of PRKAA2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
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G |
Prkcd |
protein kinase C, delta |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of PRKCD protein |
CTD |
PMID:28073184 |
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NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
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G |
Prkce |
protein kinase C, epsilon |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of PRKCE protein |
CTD |
PMID:28073184 |
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NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
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G |
Prkd3 |
protein kinase D3 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of PRKD3 protein |
CTD |
PMID:28073184 |
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NCBI chr 6:16,032,507...16,108,444
Ensembl chr 6:16,032,585...16,108,443
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G |
Proser2 |
proline and serine rich 2 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of PROSER2 protein |
CTD |
PMID:28073184 |
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NCBI chr17:72,151,961...72,187,524
Ensembl chr17:72,151,872...72,185,825
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G |
Prpf40a |
pre-mRNA processing factor 40 homolog A |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of PRPF40A protein |
CTD |
PMID:28073184 |
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NCBI chr 3:37,625,585...37,689,859
Ensembl chr 3:37,627,690...37,690,886
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G |
Prrc2b |
proline-rich coiled-coil 2B |
affects phosphorylation |
ISO |
Palmitic Acid affects the phosphorylation of PRRC2B protein |
CTD |
PMID:28073184 |
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NCBI chr 3:15,433,357...15,519,105
Ensembl chr 3:15,465,294...15,519,104
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G |
Psen1 |
presenilin 1 |
decreases expression multiple interactions |
EXP |
Palmitic Acid results in decreased expression of PSEN1 mRNA; Palmitic Acid results in decreased expression of PSEN1 protein MIR141 mRNA promotes the reaction [Palmitic Acid results in decreased expression of PSEN1 mRNA]; MIR141 mRNA promotes the reaction [Palmitic Acid results in decreased expression of PSEN1 protein] |
CTD |
PMID:34897970 |
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NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650
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G |
Psmc3ip |
PSMC3 interacting protein |
increases expression |
ISO |
Palmitic Acid results in increased expression of PSMC3IP mRNA |
CTD |
PMID:17658692 |
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NCBI chr10:86,024,281...86,027,928
Ensembl chr10:86,023,950...86,027,423
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G |
Pten |
phosphatase and tensin homolog |
increases expression multiple interactions |
EXP |
Palmitic Acid results in increased expression of PTEN protein MIR141 mRNA promotes the reaction [Palmitic Acid results in increased expression of PTEN protein] |
CTD |
PMID:34897970 |
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NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
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G |
Ptges3 |
prostaglandin E synthase 3 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of PTGES3 protein |
CTD |
PMID:28073184 |
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NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
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G |
Ptpn1 |
protein tyrosine phosphatase, non-receptor type 1 |
increases expression |
ISO |
Palmitic Acid results in increased expression of PTPN1 protein |
CTD |
PMID:22509299 |
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NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
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G |
Ptx3 |
pentraxin 3 |
increases expression |
ISO |
Palmitic Acid results in increased expression of PTX3 mRNA |
CTD |
PMID:32347412 |
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NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323
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G |
Pycard |
PYD and CARD domain containing |
affects localization |
ISO |
Palmitic Acid affects the localization of PYCARD protein |
CTD |
PMID:27689324 |
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NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
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G |
Rab18 |
RAB18, member RAS oncogene family |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RAB18 mRNA |
CTD |
PMID:30547786 |
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NCBI chr17:54,944,099...54,976,093
Ensembl chr17:54,943,955...54,976,043
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G |
Racgap1 |
Rac GTPase-activating protein 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of RACGAP1 protein |
CTD |
PMID:28073184 |
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NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
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G |
Rad18 |
RAD18 E3 ubiquitin protein ligase |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of RAD18 protein |
CTD |
PMID:28073184 |
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NCBI chr 4:145,735,654...145,821,102
Ensembl chr 4:145,735,654...145,821,069
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G |
Ralbp1 |
ralA binding protein 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of RALBP1 protein |
CTD |
PMID:28073184 |
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NCBI chr 9:105,456,425...105,493,235
Ensembl chr 9:105,456,425...105,492,707
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G |
Ralgapa2 |
Ral GTPase activating protein catalytic subunit alpha 2 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of RALGAPA2 protein |
CTD |
PMID:28073184 |
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NCBI chr 3:133,658,725...133,938,821
Ensembl chr 3:133,659,761...133,938,916
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G |
Rapgef2 |
Rap guanine nucleotide exchange factor 2 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of RAPGEF2 protein |
CTD |
PMID:28073184 |
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NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247
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G |
Rb1cc1 |
RB1-inducible coiled-coil 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of RB1CC1 protein |
CTD |
PMID:28073184 |
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NCBI chr 5:13,161,648...13,225,560
Ensembl chr 5:13,161,648...13,225,560
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G |
Rbm15 |
RNA binding motif protein 15 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of RBM15 protein |
CTD |
PMID:28073184 |
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NCBI chr 2:194,945,974...194,954,498
Ensembl chr 2:194,945,974...194,954,703
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G |
Rbm34 |
RNA binding motif protein 34 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of RBM34 protein |
CTD |
PMID:28073184 |
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NCBI chr19:54,936,516...54,956,810
Ensembl chr19:54,936,531...54,956,715
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G |
Rcc1 |
regulator of chromosome condensation 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of RCC1 protein |
CTD |
PMID:28073184 |
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NCBI chr 5:144,526,025...144,544,445
Ensembl chr 5:144,526,025...144,544,577
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G |
Rcc1l |
RCC1 like |
increases expression |
ISO |
Palmitic Acid results in increased expression of RCC1L protein |
CTD |
PMID:37117602 |
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NCBI chr12:22,543,125...22,574,042
Ensembl chr12:22,543,734...22,574,036
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
increases phosphorylation multiple interactions |
ISO EXP |
Palmitic Acid results in increased phosphorylation of RELA protein 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid results in increased phosphorylation of and results in increased activity of RELA protein]; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of RELA mRNA; cyanidin-3-O-beta-glucopyranoside inhibits the reaction [Palmitic Acid affects the localization of and results in increased activity of RELA protein]; Palmitic Acid affects the localization of and results in increased activity of RELA protein; Palmitic Acid results in increased phosphorylation of and results in increased activity of RELA protein; tin protoporphyrin IX inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid results in increased phosphorylation of and results in increased activity of RELA protein]]; wedelolactone inhibits the reaction [Palmitic Acid affects the localization of and results in increased activity of RELA protein] AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]; dorsomorphin inhibits the reaction [AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]]; dorsomorphin inhibits the reaction [Metformin inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]]; dorsomorphin inhibits the reaction [Resveratrol inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]]; dorsomorphin inhibits the reaction [Salicylic Acid inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]]; Metformin inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]; Niacinamide inhibits the reaction [AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]]; Niacinamide inhibits the reaction [Metformin inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]]; Niacinamide inhibits the reaction [Resveratrol inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]]; Niacinamide inhibits the reaction [Salicylic Acid inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]]; Resveratrol inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]; Salicylic Acid inhibits the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]; STING1 protein promotes the reaction [Palmitic Acid results in increased phosphorylation of RELA protein] |
CTD |
PMID:21745629 PMID:25108154 PMID:25815690 PMID:26422990 PMID:32613381 PMID:35235096 More...
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Repin1 |
replication initiator 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of REPIN1 protein |
CTD |
PMID:28073184 |
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NCBI chr 4:77,548,724...77,554,242
Ensembl chr 4:77,548,849...77,554,257
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G |
Rheb |
Ras homolog, mTORC1 binding |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHEB mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160
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G |
Rhob |
ras homolog family member B |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHOB mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of RHOB mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
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G |
Rnasel |
ribonuclease L |
increases expression |
ISO |
Palmitic Acid results in increased expression of RNASEL protein |
CTD |
PMID:24651439 |
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NCBI chr13:65,894,990...65,910,354
Ensembl chr13:65,901,459...65,908,704
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G |
Rock2 |
Rho-associated coiled-coil containing protein kinase 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ROCK2 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ROCK2 protein |
CTD |
PMID:30547786 |
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NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031
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G |
Rprd2 |
regulation of nuclear pre-mRNA domain containing 2 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of RPRD2 protein |
CTD |
PMID:28073184 |
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NCBI chr 2:183,311,132...183,367,959
Ensembl chr 2:183,293,114...183,367,407
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G |
Rps6 |
ribosomal protein S6 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of RPS6 protein |
CTD |
PMID:28073184 |
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NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602 Ensembl chr 5:101,371,136...101,374,602
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G |
Rps6kb1 |
ribosomal protein S6 kinase B1 |
decreases phosphorylation multiple interactions |
ISO EXP |
Palmitic Acid results in decreased phosphorylation of RPS6KB1 protein [Palmitic Acid co-treated with sodium bisulfide] inhibits the reaction [INS protein results in increased phosphorylation of RPS6KB1 protein] |
CTD |
PMID:28073184 PMID:35577173 |
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NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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G |
Rrbp1 |
ribosome binding protein 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of RRBP1 protein |
CTD |
PMID:28073184 |
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NCBI chr 3:131,314,996...131,376,930
Ensembl chr 3:131,314,998...131,376,981
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G |
Rrp1b |
ribosomal RNA processing 1B |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of RRP1B protein |
CTD |
PMID:28073184 |
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NCBI chr20:10,123,111...10,148,704
Ensembl chr20:10,123,125...10,147,928
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G |
Rrp9 |
ribosomal RNA processing 9, U3 small nucleolar RNA binding protein |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of RRP9 protein |
CTD |
PMID:28073184 |
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NCBI chr 8:107,116,411...107,126,123
Ensembl chr 8:107,117,471...107,126,123
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G |
Runx2 |
RUNX family transcription factor 2 |
increases expression multiple interactions |
EXP |
Palmitic Acid results in increased expression of RUNX2 mRNA acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of RUNX2 mRNA]; CYBA mutant form inhibits the reaction [Palmitic Acid results in increased expression of RUNX2 mRNA]; U 0126 inhibits the reaction [Palmitic Acid results in increased expression of RUNX2 mRNA] |
CTD |
PMID:24080574 |
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NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
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G |
Sbsn |
suprabasin |
increases expression |
ISO |
Palmitic Acid results in increased expression of SBSN mRNA |
CTD |
PMID:32347412 |
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NCBI chr 1:85,978,970...86,006,034
Ensembl chr 1:86,001,567...86,006,034
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G |
Scaf1 |
SR-related CTD-associated factor 1 |
affects phosphorylation |
ISO |
Palmitic Acid affects the phosphorylation of SCAF1 protein |
CTD |
PMID:28073184 |
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NCBI chr 1:95,485,448...95,499,389
Ensembl chr 1:95,485,448...95,496,029
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G |
Scd |
stearoyl-CoA desaturase |
increases expression multiple interactions decreases response to substance |
EXP ISO |
Palmitic Acid results in increased expression of SCD1 mRNA [osteum co-treated with Palmitic Acid] results in increased expression of SCD1 protein; acanthoic acid inhibits the reaction [Palmitic Acid results in increased expression of SCD1 mRNA]; decabromobiphenyl ether promotes the reaction [[osteum co-treated with Palmitic Acid] results in increased expression of SCD1 protein]; GW 3965 inhibits the reaction [Palmitic Acid results in increased expression of SCD1 mRNA]; pregna-4,17-diene-3,16-dione inhibits the reaction [Palmitic Acid results in increased expression of SCD1 mRNA] (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SCD mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SCD mRNA; Bezafibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA] Palmitic Acid results in increased expression of SCD1 mRNA; Palmitic Acid results in increased expression of SCD1 protein SCD1 protein results in decreased susceptibility to Palmitic Acid SCD1 protein inhibits the reaction [Palmitic Acid results in increased abundance of Ceramides]; SCD1 protein inhibits the reaction [Palmitic Acid results in increased abundance of Reactive Oxygen Species]; SCD1 protein inhibits the reaction [Palmitic Acid results in increased activity of CASP3 protein] |
CTD |
PMID:22413010 PMID:29414781 PMID:30547786 PMID:31421115 PMID:32613381 PMID:34757160 More...
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NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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G |
Sec22b |
SEC22 homolog B, vesicle trafficking protein |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of SEC22B protein |
CTD |
PMID:28073184 |
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NCBI chr 2:185,500,029...185,520,811
Ensembl chr 2:185,500,004...185,522,026
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G |
Sele |
selectin E |
increases expression multiple interactions |
ISO |
Palmitic Acid results in increased expression of SELE mRNA cyanidin-3-O-beta-glucopyranoside inhibits the reaction [Palmitic Acid results in increased expression of SELE mRNA]; wedelolactone inhibits the reaction [Palmitic Acid results in increased expression of SELE mRNA] |
CTD |
PMID:26422990 |
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NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
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G |
Septin9 |
septin 9 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of SEPTIN9 protein |
CTD |
PMID:28073184 |
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NCBI chr10:102,409,798...102,579,056
Ensembl chr10:102,409,711...102,579,055
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G |
Serpine1 |
serpin family E member 1 |
increases expression multiple interactions |
ISO |
Palmitic Acid results in increased expression of SERPINE1 mRNA [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SERPINE1 mRNA |
CTD |
PMID:17658692 PMID:30547786 |
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NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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G |
Sf3b2 |
splicing factor 3b, subunit 2 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of SF3B2 protein |
CTD |
PMID:28073184 |
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NCBI chr 1:202,570,423...202,590,774
Ensembl chr 1:202,570,423...202,590,759
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G |
Shroom3 |
shroom family member 3 |
affects phosphorylation |
ISO |
Palmitic Acid affects the phosphorylation of SHROOM3 protein |
CTD |
PMID:28073184 |
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NCBI chr14:15,099,415...15,396,832
Ensembl chr14:15,099,423...15,396,915
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G |
Sirt1 |
sirtuin 1 |
decreases expression increases expression multiple interactions decreases activity |
EXP ISO |
Palmitic Acid results in decreased expression of SIRT1 mRNA; Palmitic Acid results in decreased expression of SIRT1 protein Palmitic Acid results in increased expression of SIRT1 mRNA [Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of SIRT1 mRNA; Palmitic Acid inhibits the reaction [sodium arsenite results in increased expression of SIRT1 mRNA]; Palmitic Acid promotes the reaction [[sodium arsenite co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of SIRT1 mRNA]; sodium arsenite inhibits the reaction [Palmitic Acid results in increased expression of SIRT1 mRNA]; sodium arsenite promotes the reaction [[Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of SIRT1 mRNA] Palmitic Acid results in decreased activity of SIRT1 protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [Palmitic Acid results in decreased activity of SIRT1 protein]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide promotes the reaction [Palmitic Acid results in decreased activity of SIRT1 protein]; [Fructose co-treated with Palmitic Acid] results in decreased expression of SIRT1 protein; [Palmitic Acid co-treated with Glucose] promotes the reaction [Glutathione binds to SIRT1 protein]; [Palmitic Acid co-treated with Glucose] results in increased oxidation of and results in decreased activity of SIRT1 protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of SIRT1 protein]; GLRX protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] promotes the reaction [Glutathione binds to SIRT1 protein]]; GLRX protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased oxidation of and results in decreased activity of SIRT1 protein]; Resveratrol inhibits the reaction [Palmitic Acid results in decreased activity of SIRT1 protein]; SIRT1 protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased acetylation of TP53 protein]; SIRT1 protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased cleavage of CASP3 protein]; SIRT1 protein inhibits the reaction [Palmitic Acid results in decreased activity of SIRT1 protein]; SIRT1 protein mutant form inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased expression of BBC3 mRNA]; SIRT1 protein mutant form inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased expression of CDKN1A mRNA]; SIRT1 protein promotes the reaction [Resveratrol inhibits the reaction [Palmitic Acid results in decreased activity of SIRT1 protein]] [Ethanol co-treated with Oleic Acid co-treated with Palmitic Acid] results in decreased expression of SIRT1 protein; Lead promotes the reaction [Palmitic Acid results in decreased expression of SIRT1 protein]; Palmitic Acid promotes the reaction [Lead results in decreased expression of SIRT1 protein]; Resveratrol inhibits the reaction [Palmitic Acid results in decreased expression of SIRT1 mRNA]; SRT1720 inhibits the reaction [Lead promotes the reaction [Palmitic Acid results in decreased expression of SIRT1 protein]]; SRT1720 inhibits the reaction [Palmitic Acid promotes the reaction [Lead results in decreased expression of SIRT1 protein]] |
CTD |
PMID:22968147 PMID:24451382 PMID:25108154 PMID:25943029 PMID:26854922 PMID:32730863 PMID:34968464 PMID:37244597 More...
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NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
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G |
Sirt3 |
sirtuin 3 |
decreases expression |
ISO |
Palmitic Acid results in decreased expression of SIRT3 protein |
CTD |
PMID:30958623 |
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NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808
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G |
Slc1a3 |
solute carrier family 1 member 3 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of SLC1A3 protein |
CTD |
PMID:28073184 |
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NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605
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G |
Slc23a2 |
solute carrier family 23 member 2 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of SLC23A2 protein |
CTD |
PMID:28073184 |
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NCBI chr 3:119,302,651...119,395,289
Ensembl chr 3:119,302,666...119,460,343
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G |
Slc25a20 |
solute carrier family 25 member 20 |
increases expression |
EXP |
Palmitic Acid results in increased expression of SLC25A20 mRNA; Palmitic Acid results in increased expression of SLC25A20 protein |
CTD |
PMID:24349266 |
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NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
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G |
Slc2a1 |
solute carrier family 2 member 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SLC2A1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
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G |
Slc2a2 |
solute carrier family 2 member 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of SLC2A2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
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G |
Slc2a4 |
solute carrier family 2 member 4 |
decreases expression multiple interactions |
EXP ISO |
Palmitic Acid results in decreased expression of SLC2A4 protein [Palmitic Acid co-treated with Arsenic] affects the expression of SLC2A4 mRNA 4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein affects the localization of SLC2A4 protein]]; Palmitic Acid inhibits the reaction [INS protein affects the localization of SLC2A4 protein]; Quercetin inhibits the reaction [Palmitic Acid results in decreased expression of SLC2A4 protein] |
CTD |
PMID:22713545 PMID:25109277 PMID:28073184 PMID:33736254 |
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NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
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G |
Slc38a2 |
solute carrier family 38, member 2 |
multiple interactions affects expression |
ISO |
[Palmitic Acid co-treated with Arsenic] affects the expression of SLC38A2 mRNA Palmitic Acid affects the expression of SLC38A2 mRNA |
CTD |
PMID:33736254 |
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NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436
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G |
Slc4a1ap |
solute carrier family 4 member 1 adaptor protein |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of SLC4A1AP protein |
CTD |
PMID:28073184 |
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NCBI chr 6:24,905,941...24,933,651
Ensembl chr 6:24,905,941...24,933,815
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G |
Smarca4 |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of SMARCA4 protein |
CTD |
PMID:28073184 |
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NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975
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G |
Smg1 |
SMG1, nonsense mediated mRNA decay associated PI3K related kinase |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of SMG1 protein |
CTD |
PMID:28073184 |
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NCBI chr 1:172,441,892...172,543,667
Ensembl chr 1:172,444,936...172,543,698
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G |
Smim20 |
small integral membrane protein 20 |
multiple interactions |
ISO |
Palmitic Acid inhibits the reaction [SMIM20 protein results in increased phosphorylation of CREB1 protein] |
CTD |
PMID:30716364 |
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NCBI chr14:57,711,304...57,722,681
Ensembl chr14:57,711,307...57,722,681
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G |
Snap23 |
synaptosome associated protein 23 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SNAP23 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SNAP23 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 3:107,514,088...107,546,177
Ensembl chr 3:107,514,131...107,544,320
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G |
Snapin |
SNAP-associated protein |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of SNAPIN protein |
CTD |
PMID:28073184 |
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NCBI chr 2:175,971,575...175,974,164
Ensembl chr 2:175,971,257...175,974,231
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G |
Socs1 |
suppressor of cytokine signaling 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOCS1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
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G |
Socs2 |
suppressor of cytokine signaling 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SOCS2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548
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G |
Socs3 |
suppressor of cytokine signaling 3 |
multiple interactions affects expression |
ISO |
[Palmitic Acid co-treated with Arsenic] affects the expression of SOCS3 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS3 mRNA Palmitic Acid affects the expression of SOCS3 mRNA |
CTD |
PMID:30547786 PMID:33736254 |
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NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
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G |
Sod1 |
superoxide dismutase 1 |
decreases expression multiple interactions |
ISO EXP |
Palmitic Acid results in decreased expression of SOD1 mRNA [Glucose co-treated with Palmitic Acid] results in decreased expression of SOD1 protein rosiglitazone inhibits the reaction [Palmitic Acid results in decreased expression of SOD1 mRNA] |
CTD |
PMID:18155663 PMID:28027979 |
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
increases expression multiple interactions decreases expression |
EXP ISO |
Palmitic Acid results in increased expression of SOD2 mRNA [osteum co-treated with Palmitic Acid] results in decreased expression of SOD2 protein [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOD2 mRNA Palmitic Acid results in decreased expression of SOD2 mRNA; Palmitic Acid results in decreased expression of SOD2 protein |
CTD |
PMID:24349266 PMID:28027979 PMID:30547786 PMID:35798905 |
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Son |
SON DNA and RNA binding protein |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of SON protein |
CTD |
PMID:28073184 |
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NCBI chr11:30,850,890...30,923,167
Ensembl chr11:30,892,005...30,923,167
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G |
Sort1 |
sortilin 1 |
multiple interactions increases degradation increases phosphorylation |
ISO |
Cycloheximide promotes the reaction [Palmitic Acid results in increased degradation of SORT1 protein]; Docosahexaenoic Acids inhibits the reaction [Cycloheximide promotes the reaction [Palmitic Acid results in increased degradation of SORT1 protein]]; Docosahexaenoic Acids inhibits the reaction [Palmitic Acid results in decreased expression of SORT1 protein]; Eicosapentaenoic Acid inhibits the reaction [Palmitic Acid results in decreased expression of SORT1 protein] Palmitic Acid results in increased phosphorylation of SORT1 protein |
CTD |
PMID:24986865 |
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NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354
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G |
Sowahc |
sosondowah ankyrin repeat domain family member C |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of SOWAHC protein |
CTD |
PMID:28073184 |
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NCBI chr20:27,195,198...27,199,664
Ensembl chr20:27,193,743...27,265,018 Ensembl chr20:27,193,743...27,265,018
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G |
Spag1 |
sperm associated antigen 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of SPAG1 protein |
CTD |
PMID:28073184 |
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NCBI chr 7:67,361,474...67,421,369
Ensembl chr 7:67,361,477...67,421,368
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G |
Spag7 |
sperm associated antigen 7 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of SPAG7 protein |
CTD |
PMID:28073184 |
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NCBI chr10:55,377,249...55,383,404
Ensembl chr10:55,377,249...55,383,404
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G |
Spast |
spastin |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of SPAST protein |
CTD |
PMID:28073184 |
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NCBI chr 6:21,055,349...21,106,586
Ensembl chr 6:21,055,349...21,107,954
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G |
Specc1 |
sperm antigen with calponin homology and coiled-coil domains 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of SPECC1 protein |
CTD |
PMID:28073184 |
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NCBI chr10:46,638,947...46,912,989
Ensembl chr10:46,638,809...46,912,802
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G |
Sqstm1 |
sequestosome 1 |
increases expression multiple interactions |
ISO EXP |
Palmitic Acid results in increased expression of SQSTM1 protein CYLD protein affects the reaction [Palmitic Acid results in increased expression of SQSTM1 protein]; PKF115-584 inhibits the reaction [CYLD protein affects the reaction [Palmitic Acid results in increased expression of SQSTM1 protein]]; SQSTM1 protein affects the reaction [Palmitic Acid affects the localization of AIFM1 protein]; SQSTM1 protein affects the reaction [Palmitic Acid results in increased cleavage of CASP3 protein] Deferoxamine promotes the reaction [Palmitic Acid results in increased expression of SQSTM1 protein]; Palmitic Acid inhibits the reaction [Arsenic Trioxide results in decreased expression of SQSTM1 protein]; trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SQSTM1 protein] |
CTD |
PMID:30208301 PMID:30362509 PMID:32278738 PMID:32283200 PMID:34774660 |
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NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
multiple interactions decreases expression increases expression |
ISO EXP |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 protein; ATG5 protein promotes the reaction [Resveratrol inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]]; ATG7 protein affects the reaction [trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]]; BECN1 protein promotes the reaction [Resveratrol inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]]; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 protein]; Resveratrol inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]; trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein] Palmitic Acid results in decreased expression of SREBF1 mRNA [osteum co-treated with Palmitic Acid] results in increased expression of SREBF1 protein; [Palmitic Acid co-treated with Ethanol] results in increased expression of SREBF1 mRNA; [Palmitic Acid co-treated with sodium arsenite] results in decreased expression of SREBF1 mRNA; acanthoic acid inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 mRNA]; acanthoic acid inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]; amlexanox inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 mRNA]; decabromobiphenyl ether promotes the reaction [[osteum co-treated with Palmitic Acid] results in increased expression of SREBF1 protein]; GW 3965 inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 mRNA]; GW 3965 inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]; trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein] Palmitic Acid results in increased expression of SREBF1 mRNA; Palmitic Acid results in increased expression of SREBF1 protein; Palmitic Acid results in increased expression of SREBF1 protein modified form [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased expression of SREBF1 protein; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA] |
CTD |
PMID:25943029 PMID:26190035 PMID:26854922 PMID:29414781 PMID:30208301 PMID:31421115 PMID:32905826 PMID:34757160 PMID:34968464 PMID:36347319 PMID:37271273 More...
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NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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G |
Srrm1 |
serine and arginine repetitive matrix 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of SRRM1 protein |
CTD |
PMID:28073184 |
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NCBI chr 5:147,559,515...147,591,895
Ensembl chr 5:147,559,514...147,591,849
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G |
Srrm2 |
serine/arginine repetitive matrix 2 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of SRRM2 protein |
CTD |
PMID:28073184 |
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NCBI chr10:12,815,471...12,848,750
Ensembl chr10:12,815,471...12,848,751
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G |
Stat3 |
signal transducer and activator of transcription 3 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of STAT3 protein |
CTD |
PMID:28073184 |
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NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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G |
Sting1 |
stimulator of interferon response cGAMP interactor 1 |
multiple interactions increases expression |
EXP |
STING1 protein promotes the reaction [Palmitic Acid results in increased expression of and results in increased secretion of IL1B protein]; STING1 protein promotes the reaction [Palmitic Acid results in increased phosphorylation of RELA protein]; STING1 protein promotes the reaction [Palmitic Acid results in increased secretion of IL18 protein] Palmitic Acid results in increased expression of STING1 mRNA; Palmitic Acid results in increased expression of STING1 protein |
CTD |
PMID:35235096 |
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NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335
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G |
Stk11 |
serine/threonine kinase 11 |
multiple interactions decreases phosphorylation |
ISO |
5-methyltetrahydrofolate inhibits the reaction [Palmitic Acid results in decreased phosphorylation of STK11 protein]; dorsomorphin inhibits the reaction [5-methyltetrahydrofolate inhibits the reaction [Palmitic Acid results in decreased phosphorylation of STK11 protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [5-methyltetrahydrofolate inhibits the reaction [Palmitic Acid results in decreased phosphorylation of STK11 protein]] |
CTD |
PMID:26400185 |
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NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
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G |
Sugt1 |
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of SUGT1 protein |
CTD |
PMID:28073184 |
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NCBI chr15:54,991,419...55,032,244
Ensembl chr15:54,990,672...55,069,150
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G |
Syn1 |
synapsin I |
decreases expression multiple interactions |
EXP |
Palmitic Acid results in decreased expression of SYN1 protein Lead promotes the reaction [Palmitic Acid results in decreased expression of SYN1 protein]; Palmitic Acid promotes the reaction [Lead results in decreased expression of SYN1 protein]; SRT1720 inhibits the reaction [Lead promotes the reaction [Palmitic Acid results in decreased expression of SYN1 protein]]; SRT1720 inhibits the reaction [Palmitic Acid promotes the reaction [Lead results in decreased expression of SYN1 protein]] |
CTD |
PMID:37244597 |
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NCBI chr X:1,172,208...1,227,400
Ensembl chr X:1,172,208...1,227,396
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G |
Synrg |
synergin, gamma |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of SYNRG protein |
CTD |
PMID:28073184 |
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NCBI chr10:68,848,828...68,931,252
Ensembl chr10:68,849,642...68,931,250
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G |
Tap1 |
transporter 1, ATP binding cassette subfamily B member |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Arsenic] affects the expression of TAP1 mRNA |
CTD |
PMID:33736254 |
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NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901
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G |
Tbc1d1 |
TBC1 domain family member 1 |
multiple interactions |
ISO |
TBC1D1 protein results in decreased uptake of and results in decreased oxidation of Palmitic Acid |
CTD |
PMID:18931681 |
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NCBI chr14:43,936,820...44,135,133
Ensembl chr14:43,935,636...44,136,499
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G |
Tbc1d4 |
TBC1 domain family, member 4 |
increases phosphorylation multiple interactions |
ISO EXP |
Palmitic Acid results in increased phosphorylation of TBC1D4 protein 4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of TBC1D4 protein]]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of TBC1D4 protein] |
CTD |
PMID:25109277 PMID:28073184 |
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NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265
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G |
Tbc1d5 |
TBC1 domain family, member 5 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of TBC1D5 protein |
CTD |
PMID:28073184 |
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NCBI chr 9:3,503,328...4,017,131
Ensembl chr 9:3,513,623...4,016,913
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G |
Tbk1 |
TANK-binding kinase 1 |
multiple interactions increases phosphorylation |
ISO |
amlexanox inhibits the reaction [Palmitic Acid results in increased phosphorylation of TBK1 protein] |
CTD |
PMID:32905826 |
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NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892
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G |
Tcof1 |
treacle ribosome biogenesis factor 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of TCOF1 protein |
CTD |
PMID:28073184 |
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NCBI chr18:54,267,015...54,300,324
Ensembl chr18:54,267,026...54,300,324
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G |
Tfam |
transcription factor A, mitochondrial |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of TFAM mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of TFAM mRNA] |
CTD |
PMID:26847930 |
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NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
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G |
Tfap2b |
transcription factor AP-2 beta |
multiple interactions increases expression |
ISO |
[Palmitic Acid co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of TFAP2B mRNA; Palmitic Acid inhibits the reaction [[sodium arsenite co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of TFAP2B mRNA]; Palmitic Acid promotes the reaction [sodium arsenite results in increased expression of TFAP2B mRNA]; sodium arsenite promotes the reaction [Palmitic Acid results in increased expression of TFAP2B mRNA] |
CTD |
PMID:34968464 |
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NCBI chr 9:21,786,251...21,816,054
Ensembl chr 9:21,786,258...21,814,520
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G |
Tfap2c |
transcription factor AP-2 gamma |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of TFAP2C protein |
CTD |
PMID:28073184 |
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NCBI chr 3:161,315,114...161,322,998
Ensembl chr 3:161,315,031...161,322,995
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G |
Tfpt |
TCF3 fusion partner |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of TFPT protein |
CTD |
PMID:28073184 |
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NCBI chr 1:65,587,633...65,597,407
Ensembl chr 1:65,582,359...65,611,689
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G |
Tfrc |
transferrin receptor |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in increased expression of TFRC protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of TFRC protein] |
CTD |
PMID:32976958 |
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NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
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G |
Tgfb1 |
transforming growth factor, beta 1 |
increases secretion multiple interactions |
ISO |
Palmitic Acid results in increased secretion of TGFB1 protein [Palmitic Acid co-treated with Ethanol] results in increased secretion of TGFB1 protein [Palmitic Acid co-treated with Thioacetamide] results in increased secretion of TGFB1 protein |
CTD |
PMID:30625377 PMID:37271273 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Tgfb2 |
transforming growth factor, beta 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TGFB2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TIMP1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of TIMP1 mRNA |
CTD |
PMID:26187275 PMID:30547786 |
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NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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G |
Tjp1 |
tight junction protein 1 |
decreases expression multiple interactions |
ISO |
Palmitic Acid results in decreased expression of TJP1 protein [Palmitic Acid co-treated with Arsenic] affects the expression of TJP1 mRNA CA 074 methyl ester inhibits the reaction [Palmitic Acid results in decreased expression of TJP1 protein]; Glycyrrhizic Acid inhibits the reaction [Palmitic Acid results in decreased expression of TJP1 protein]; L 709049 analog inhibits the reaction [Palmitic Acid results in decreased expression of TJP1 protein] |
CTD |
PMID:27689324 PMID:33736254 |
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NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
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G |
Tjp2 |
tight junction protein 2 |
multiple interactions decreases expression |
ISO |
CA 074 methyl ester inhibits the reaction [Palmitic Acid results in decreased expression of TJP2 protein]; Glycyrrhizic Acid inhibits the reaction [Palmitic Acid results in decreased expression of TJP2 protein]; L 709049 analog inhibits the reaction [Palmitic Acid results in decreased expression of TJP2 protein] |
CTD |
PMID:27689324 |
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NCBI chr 1:221,709,745...221,838,291
Ensembl chr 1:221,709,745...221,838,295
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G |
Tlr4 |
toll-like receptor 4 |
multiple interactions increases expression |
ISO |
Quercetin inhibits the reaction [Palmitic Acid results in increased expression of TLR4 mRNA] |
CTD |
PMID:25614714 |
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NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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G |
Tnf |
tumor necrosis factor |
multiple interactions increases secretion increases expression increases response to substance |
ISO EXP |
(R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid results in increased secretion of TNF protein]; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of PPARG mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of PPARA mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CCL2 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CCL5 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CXCL5 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NFKB1 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of PPARD mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of RELA mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ABCA1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ACSL1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT5 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AHR mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ARG1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of B4GALT5 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CAT mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CXCL2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CXCL3 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1H1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1I1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ENO3 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ERLIN1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of FOXA1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of GLUD1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of GLUD2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of HSDL2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of IL1A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of LAMB1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of NR1H4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PEBP1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PKLR mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PLD1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PNPLA3 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PPARD mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PRKAA1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RAB18 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHEB mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHOB mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SCD mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SERPINE1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SLC2A1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOCS1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOD2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TGFB2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TNFAIP2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TUBB2A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of UGCG mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of VAMP4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of VCAN mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of CPT1A protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of DST mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ACSL4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANGPTL4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANXA2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CIDEC protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CPT1A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CXCL8 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP24A1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP26A1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FGF21 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FLOT1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HIF1A protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HILPDA protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of JAK1 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of LDLR mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP3K8 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP4K4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MTTP mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PPARA mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ROCK2 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SNAP23 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS3 mRNA; [Palmitic Acid co-treated with Thioacetamide] results in increased secretion of TNF protein; Bezafibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Bezafibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Bezafibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Bezafibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Palmitic Acid inhibits the reaction [TNF protein results in increased phosphorylation of AKT1 protein]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; tin protoporphyrin IX inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid results in increased secretion of TNF protein]] Palmitic Acid results in increased expression of TNF protein Palmitic Acid results in increased expression of TNF mRNA; Palmitic Acid results in increased expression of TNF protein [Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein; [Palmitic Acid co-treated with Sincalide] results in increased expression of TNF mRNA; [Palmitic Acid co-treated with Sincalide] results in increased expression of TNF protein; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]; AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]; imoxin inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]; Metformin inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]; parthenolide inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]; pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]; Quercetin inhibits the reaction [[Sincalide co-treated with Palmitic Acid] results in increased expression of TNF protein]; Quercetin inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]; Resveratrol inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]; Salicylic Acid inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA] [Palmitic Acid co-treated with Ethanol] results in increased expression of TNF mRNA; [Palmitic Acid co-treated with Ethanol] results in increased secretion of TNF protein; amlexanox inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]; amlexanox inhibits the reaction [Palmitic Acid results in increased secretion of TNF protein]; Quercetin inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]; Quercetin inhibits the reaction [Palmitic Acid results in increased expression of TNF protein] Palmitic Acid results in increased susceptibility to TNF protein |
CTD |
PMID:18323514 PMID:22683933 PMID:22713545 PMID:25108154 PMID:25614714 PMID:25815690 PMID:26190035 PMID:26873426 PMID:30259999 PMID:30547786 PMID:30625377 PMID:30958623 PMID:32613381 PMID:32905826 PMID:33604948 PMID:37271273 More...
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfaip2 |
TNF alpha induced protein 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TNFAIP2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914
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G |
Tnfrsf9 |
TNF receptor superfamily member 9 |
increases expression multiple interactions |
ISO |
Palmitic Acid results in increased expression of TNFRSF9 mRNA Quercetin inhibits the reaction [Palmitic Acid results in increased expression of TNFRSF9 mRNA] |
CTD |
PMID:25614714 |
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NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000
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G |
Tnks1bp1 |
tankyrase 1 binding protein 1 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of TNKS1BP1 protein |
CTD |
PMID:28073184 |
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NCBI chr 3:70,135,335...70,160,071
Ensembl chr 3:70,137,837...70,160,038
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G |
Tns1 |
tensin 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of TNS1 protein |
CTD |
PMID:28073184 |
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NCBI chr 9:75,491,886...75,702,853
Ensembl chr 9:75,495,814...75,703,225
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G |
Top2a |
DNA topoisomerase II alpha |
affects phosphorylation |
ISO |
Palmitic Acid affects the phosphorylation of TOP2A protein |
CTD |
PMID:28073184 |
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NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
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G |
Tor1aip2 |
torsin 1A interacting protein 2 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of TOR1AIP2 protein |
CTD |
PMID:28073184 |
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NCBI chr13:68,225,226...68,256,536
Ensembl chr13:68,230,009...68,256,536 Ensembl chr13:68,230,009...68,256,536
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G |
Tp53 |
tumor protein p53 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of TP53 mRNA]; [Palmitic Acid co-treated with Glucose] results in increased acetylation of TP53 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of TP53 mRNA; SIRT1 protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased acetylation of TP53 protein] |
CTD |
PMID:24451382 PMID:32369900 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Tp53bp1 |
tumor protein p53 binding protein 1 |
affects phosphorylation |
ISO |
Palmitic Acid affects the phosphorylation of TP53BP1 protein |
CTD |
PMID:28073184 |
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NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822
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G |
Tp53bp2 |
tumor protein p53 binding protein, 2 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of TP53BP2 protein |
CTD |
PMID:28073184 |
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NCBI chr13:94,088,769...94,145,436
Ensembl chr13:94,088,709...94,145,432
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G |
Tpd52l2 |
TPD52 like 2 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of TPD52L2 protein |
CTD |
PMID:28073184 |
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NCBI chr 3:168,598,449...168,618,201
Ensembl chr 3:168,594,609...168,619,762
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G |
Trim63 |
tripartite motif containing 63 |
increases expression multiple interactions |
ISO |
Palmitic Acid results in increased expression of TRIM63 mRNA; Palmitic Acid results in increased expression of TRIM63 protein Quercetin inhibits the reaction [Palmitic Acid results in increased expression of TRIM63 mRNA]; Quercetin inhibits the reaction [Palmitic Acid results in increased expression of TRIM63 protein] |
CTD |
PMID:25614714 |
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NCBI chr 5:146,533,492...146,547,332
Ensembl chr 5:146,533,507...146,547,322
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G |
Tubb2a |
tubulin, beta 2A class IIa |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TUBB2A mRNA |
CTD |
PMID:30547786 |
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NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
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G |
Tufm |
Tu translation elongation factor, mitochondrial |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of TUFM mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:181,073,788...181,077,395
Ensembl chr 1:181,073,788...181,077,395
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G |
Txnip |
thioredoxin interacting protein |
increases expression multiple interactions |
ISO |
Palmitic Acid results in increased expression of TXNIP protein AICA ribonucleotide inhibits the reaction [Palmitic Acid results in increased expression of TXNIP protein]; baicalin inhibits the reaction [Palmitic Acid results in increased expression of TXNIP protein]; dorsomorphin inhibits the reaction [baicalin inhibits the reaction [Palmitic Acid results in increased expression of TXNIP protein]] |
CTD |
PMID:29031535 |
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NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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G |
Ubr4 |
ubiquitin protein ligase E3 component n-recognin 4 |
decreases phosphorylation |
ISO |
Palmitic Acid results in decreased phosphorylation of UBR4 protein |
CTD |
PMID:28073184 |
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NCBI chr 5:151,635,825...151,743,931
Ensembl chr 5:151,635,868...151,743,784
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G |
Ucp1 |
uncoupling protein 1 |
increases expression |
EXP |
Palmitic Acid results in increased expression of UCP1 mRNA |
CTD |
PMID:28027979 |
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NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852
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G |
Ucp2 |
uncoupling protein 2 |
increases activity multiple interactions increases expression |
ISO EXP |
Palmitic Acid results in increased activity of UCP2 protein [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in decreased expression of UCP2 protein; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of UCP2 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 protein; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 mRNA]; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 protein]; Triiodothyronine promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 mRNA]; Triiodothyronine promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 protein] Palmitic Acid results in increased expression of UCP2 mRNA candesartan inhibits the reaction [Palmitic Acid results in increased expression of UCP2 mRNA] |
CTD |
PMID:12858170 PMID:20667613 PMID:25048947 PMID:26854922 |
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NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
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G |
Ugcg |
UDP-glucose ceramide glucosyltransferase |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of UGCG mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of UGCG mRNA |
CTD |
PMID:30547786 |
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NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
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G |
Uri1 |
URI1, prefoldin-like chaperone |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of URI1 protein |
CTD |
PMID:28073184 |
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NCBI chr 1:90,646,392...90,704,811
Ensembl chr 1:90,646,393...90,709,026
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G |
Usp1 |
ubiquitin specific peptidase 1 |
increases phosphorylation |
ISO |
Palmitic Acid results in increased phosphorylation of USP1 protein |
CTD |
PMID:28073184 |
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NCBI chr 5:113,587,564...113,598,934
Ensembl chr 5:113,587,564...113,598,932
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G |
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