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ONTOLOGY REPORT - ANNOTATIONS

Term:S-adenosylhomocysteine metabolic process
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Accession:GO:0046498 term browser browse the term
Definition:The chemical reactions and pathways involving S-adenosylhomocysteine; the L-enantiomer is formed from S-adenosylmethionine and is a strong inhibitor of S-adenosylmethionine-mediated methylation reactions. It can be cleaved to form adenosine and homocysteine.
Synonyms:exact_synonym: S-adenosylhomocysteine metabolism

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S-adenosylhomocysteine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G R Comt catechol-O-methyltransferase TAS RGD PMID:12584150 RGD:1359089 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G N Gamt guanidinoacetate N-methyltransferase ISO RGD PMID:15533043 RGD:1359081 NCBI chrNW_004624828:7,294,380...7,297,787
Ensembl chrNW_004624828:7,294,327...7,297,303 		JBrowse link
G G GAMT guanidinoacetate N-methyltransferase ISO RGD PMID:15533043 RGD:1359081 NCBI chr 6:1,165,016...1,178,458
Ensembl chr 6:1,164,259...1,178,354 		JBrowse link
G P GAMT guanidinoacetate N-methyltransferase ISO RGD PMID:15533043 RGD:1359081 NCBI chr 2:77,076,566...77,079,751
Ensembl chr 2:77,076,566...77,079,759 		JBrowse link
G S Gamt guanidinoacetate N-methyltransferase ISO RGD PMID:15533043 RGD:1359081 NCBI chrNW_004936588:721,436...724,475
Ensembl chrNW_004936588:721,313...724,524 		JBrowse link
G D GAMT guanidinoacetate N-methyltransferase ISO RGD PMID:15533043 RGD:1359081 NCBI chr20:57,440,698...57,442,588 JBrowse link
G B GAMT guanidinoacetate N-methyltransferase ISO RGD PMID:15533043 RGD:1359081 Ensembl chr19:1,371,312...1,375,461 JBrowse link
G C Gamt guanidinoacetate N-methyltransferase ISO RGD PMID:15533043 RGD:1359081 NCBI chrNW_004955495:6,536,541...6,539,424
Ensembl chrNW_004955495:6,536,544...6,539,424 		JBrowse link
G R Gamt guanidinoacetate N-methyltransferase IDA RGD PMID:15533043 RGD:1359081 NCBI chr 7:9,448,590...9,451,413
Ensembl chr 7:9,448,628...9,451,778 		JBrowse link
G M Gamt guanidinoacetate methyltransferase involved_in ISO RGD
MGI		 PMID:15533043 GO_REF:0000096 MGI:4417868 RGD:1359081 NCBI chr10:80,093,985...80,096,846
Ensembl chr10:80,093,985...80,096,846 		JBrowse link
G H GAMT guanidinoacetate N-methyltransferase ISO RGD PMID:15533043 RGD:1359081 NCBI chr19:1,397,026...1,401,542
Ensembl chr19:1,397,026...1,401,570 		JBrowse link
G G GNMT glycine N-methyltransferase involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:15347642 GO_REF:0000118 RGD:1359070 NCBI chr17:29,196,142...29,199,728
Ensembl chr17:29,196,321...29,198,947 		JBrowse link
G P GNMT glycine N-methyltransferase involved_in ISO
IEA
IBA		 RGD
TreeGrafter
GO_Central		 PMID:15347642 GO_REF:0000033 GO_REF:0000118 RGD:1359070 NCBI chr 7:38,038,359...38,041,218
Ensembl chr 7:38,038,358...38,041,217 		JBrowse link
G S Gnmt glycine N-methyltransferase involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:15347642 GO_REF:0000118 RGD:1359070 NCBI chrNW_004936476:16,961,734...16,965,487
Ensembl chrNW_004936476:16,957,270...16,965,346 		JBrowse link
G D GNMT glycine N-methyltransferase involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:15347642 GO_REF:0000118 RGD:1359070 NCBI chr12:11,500,363...11,503,075
Ensembl chr12:11,500,392...11,503,481 		JBrowse link
G B GNMT glycine N-methyltransferase involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:15347642 GO_REF:0000118 RGD:1359070 NCBI chr 6:42,550,631...42,554,385
Ensembl chr 6:43,846,560...43,849,679 		JBrowse link
G C Gnmt glycine N-methyltransferase involved_in ISO PMID:10756111 RGD
CAFA		 PMID:10756111 PMID:15347642 RGD:12793006 RGD:1359070 NCBI chrNW_004955437:8,944,288...8,946,642
Ensembl chrNW_004955437:8,944,047...8,946,642 		JBrowse link
G R Gnmt glycine N-methyltransferase involved_in IDA
IBA
IMP		 GO_REF:0000033
PMID:10756111		 GO_Central
RGD		 PMID:15347642 PMID:10756111 GO_REF:0000033, RGD:1359070, RGD:12793006 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434 		JBrowse link
G M Gnmt glycine N-methyltransferase involved_in ISO
IBA		 RGD
GO_Central
MGI		 PMID:15347642 GO_REF:0000033 GO_REF:0000096 MGI:4417868 RGD:1359070 NCBI chr17:47,036,590...47,040,091
Ensembl chr17:47,036,590...47,040,094 		JBrowse link
G H GNMT glycine N-methyltransferase involved_in ISO
IEA
IBA		 RGD
TreeGrafter
GO_Central		 PMID:15347642 GO_REF:0000033 GO_REF:0000118 RGD:1359070 NCBI chr 6:42,960,754...42,963,880
Ensembl chr 6:42,960,754...42,963,880 		JBrowse link
G D GPR153 G protein-coupled receptor 153 ISO RGD PMID:9192075 RGD:2289655 NCBI chr 5:60,119,793...60,128,531
Ensembl chr 5:60,123,054...60,149,027 		JBrowse link
G N Icmt isoprenylcysteine carboxyl methyltransferase ISO RGD PMID:9192075 RGD:2289655 NCBI chrNW_004624818:5,165,923...5,174,761
Ensembl chrNW_004624818:5,165,876...5,174,828 		JBrowse link
G G ICMT isoprenylcysteine carboxyl methyltransferase ISO RGD PMID:9192075 RGD:2289655 NCBI chr20:125,504,240...125,516,749
Ensembl chr20:125,504,325...125,515,160 		JBrowse link
G P ICMT isoprenylcysteine carboxyl methyltransferase ISO RGD PMID:9192075 RGD:2289655 NCBI chr 6:67,116,943...67,125,908
Ensembl chr 6:67,116,946...67,123,810 		JBrowse link
G B ICMT isoprenylcysteine carboxyl methyltransferase ISO RGD PMID:9192075 RGD:2289655 NCBI chr 1:4,987,384...5,002,213
Ensembl chr 1:6,246,570...6,258,746 		JBrowse link
G C Icmt isoprenylcysteine carboxyl methyltransferase ISO RGD PMID:9192075 RGD:2289655 NCBI chrNW_004955486:6,280,838...6,289,584
Ensembl chrNW_004955486:6,280,125...6,289,584 		JBrowse link
G R Icmt isoprenylcysteine carboxyl methyltransferase IMP RGD PMID:9192075 RGD:2289655 NCBI chr 5:162,804,368...162,811,129
Ensembl chr 5:162,804,368...162,811,128 		JBrowse link
G M Icmt isoprenylcysteine carboxyl methyltransferase involved_in ISO RGD
MGI		 PMID:9192075 GO_REF:0000096 MGI:4417868 RGD:2289655 NCBI chr 4:152,381,671...152,391,583
Ensembl chr 4:152,381,684...152,391,578 		JBrowse link
G H ICMT isoprenylcysteine carboxyl methyltransferase involved_in ISO
IEA		 RGD
Ensembl		 PMID:9192075 GO_REF:0000107 RGD:2289655 NCBI chr 1:6,221,193...6,235,964
Ensembl chr 1:6,221,193...6,235,972 		JBrowse link
G N LOC101697457 glycine N-methyltransferase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624754:16,522,771...16,525,292
Ensembl chrNW_004624754:16,520,823...16,525,512 		JBrowse link
G N Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase ISO RGD PMID:8263531 RGD:729481 NCBI chrNW_004624785:8,267,328...8,326,550
Ensembl chrNW_004624785:8,263,113...8,326,549 		JBrowse link
G G PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase ISO RGD PMID:8263531 RGD:729481 NCBI chr13:21,808,583...21,867,309
Ensembl chr13:21,807,710...21,866,768 		JBrowse link
G P PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase ISO RGD PMID:8263531 RGD:729481 NCBI chr 1:16,202,859...16,249,879
Ensembl chr 1:16,198,223...16,249,531 		JBrowse link
G S Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase ISO RGD PMID:8263531 RGD:729481 NCBI chrNW_004936489:2,677,740...2,720,387
Ensembl chrNW_004936489:2,677,484...2,722,263 		JBrowse link
G D PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase ISO RGD PMID:8263531 RGD:729481 NCBI chr 1:40,494,441...40,539,453
Ensembl chr 1:40,494,461...40,538,937 		JBrowse link
G B PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase ISO RGD PMID:8263531 RGD:729481 NCBI chr 6:147,564,783...147,623,402 JBrowse link
G C Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase ISO RGD PMID:8263531 RGD:729481 NCBI chrNW_004955439:11,480,094...11,531,842
Ensembl chrNW_004955439:11,480,101...11,531,839 		JBrowse link
G R Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 IDA RGD PMID:8263531 RGD:729481 NCBI chr 1:2,111,756...2,160,354
Ensembl chr 1:2,111,763...2,159,201 		JBrowse link
G M Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 involved_in ISO RGD
MGI		 PMID:8263531 GO_REF:0000096 MGI:4417868 RGD:729481 NCBI chr10:7,503,608...7,556,922
Ensembl chr10:7,505,137...7,556,900 		JBrowse link
G H PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase ISO RGD PMID:8263531 RGD:729481 NCBI chr 6:149,749,695...149,811,421
Ensembl chr 6:149,749,444...149,811,420 		JBrowse link
G N Pemt phosphatidylethanolamine N-methyltransferase ISO RGD PMID:8344945 RGD:729486 NCBI chrNW_004624849:3,818,115...3,907,250
Ensembl chrNW_004624849:3,817,915...3,908,888 		JBrowse link
G G PEMT phosphatidylethanolamine N-methyltransferase ISO RGD PMID:8344945 RGD:729486 NCBI chr16:16,540,096...16,626,251
Ensembl chr16:16,539,985...16,611,279 		JBrowse link
G P PEMT phosphatidylethanolamine N-methyltransferase ISO RGD PMID:8344945 RGD:729486 NCBI chr12:60,880,367...60,919,279 JBrowse link
G S Pemt phosphatidylethanolamine N-methyltransferase ISO RGD PMID:8344945 RGD:729486 NCBI chrNW_004936741:1,131,792...1,207,460
Ensembl chrNW_004936741:1,128,616...1,207,499 		JBrowse link
G D PEMT phosphatidylethanolamine N-methyltransferase ISO RGD PMID:8344945 RGD:729486 NCBI chr 5:41,871,685...41,960,831
Ensembl chr 5:41,872,108...41,960,828 		JBrowse link
G B PEMT phosphatidylethanolamine N-methyltransferase ISO RGD PMID:8344945 RGD:729486 NCBI chr17:33,703,800...33,790,470
Ensembl chr17:38,651,024...38,737,202 		JBrowse link
G C Pemt phosphatidylethanolamine N-methyltransferase ISO RGD PMID:8344945 RGD:729486 NCBI chrNW_004955577:365,031...443,138
Ensembl chrNW_004955577:367,288...443,138 		JBrowse link
G R Pemt phosphatidylethanolamine N-methyltransferase IDA RGD PMID:8344945 RGD:729486 NCBI chr10:44,775,910...44,849,990
Ensembl chr10:44,775,911...44,850,013 		JBrowse link
G M Pemt phosphatidylethanolamine N-methyltransferase involved_in ISO RGD
MGI		 PMID:8344945 GO_REF:0000096 MGI:4417868 RGD:729486 NCBI chr11:59,861,440...59,937,394
Ensembl chr11:59,861,440...59,937,315 		JBrowse link
G H PEMT phosphatidylethanolamine N-methyltransferase ISO RGD PMID:8344945 RGD:729486 NCBI chr17:17,505,563...17,592,142
Ensembl chr17:17,505,563...17,591,708 		JBrowse link
G R Pnmt phenylethanolamine-N-methyltransferase TAS RGD PMID:12438084 RGD:1359087 NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556 		JBrowse link
S-adenosylhomocysteine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G N Ahcy adenosylhomocysteinase acts_upstream_of_or_within ISO (PMID:12023972) RGD
MGI		 PMID:11741948 PMID:12023972 RGD:730275 NCBI chrNW_004624842:5,053,336...5,071,902
Ensembl chrNW_004624842:5,053,280...5,072,679 		JBrowse link
G G AHCY adenosylhomocysteinase acts_upstream_of_or_within ISO (PMID:12023972) RGD
MGI		 PMID:11741948 PMID:12023972 RGD:730275 NCBI chr 2:38,579,254...38,601,218
Ensembl chr 2:38,579,024...38,601,208 		JBrowse link
G P AHCY adenosylhomocysteinase acts_upstream_of_or_within ISO (PMID:12023972) RGD
MGI		 PMID:11741948 PMID:12023972 RGD:730275 NCBI chr17:37,726,084...37,744,378
Ensembl chr17:37,726,084...37,744,461 		JBrowse link
G S Ahcy adenosylhomocysteinase acts_upstream_of_or_within ISO (PMID:12023972) RGD
MGI		 PMID:11741948 PMID:12023972 RGD:730275 NCBI chrNW_004936561:6,314,797...6,333,961
Ensembl chrNW_004936561:6,314,705...6,334,439 		JBrowse link
G D AHCY adenosylhomocysteinase acts_upstream_of_or_within ISO (PMID:12023972) RGD
MGI		 PMID:11741948 PMID:12023972 RGD:730275 NCBI chr24:23,410,553...23,423,494
Ensembl chr24:23,411,140...23,419,767 		JBrowse link
G B AHCY adenosylhomocysteinase acts_upstream_of_or_within ISO (PMID:12023972) RGD
MGI		 PMID:11741948 PMID:12023972 RGD:730275 NCBI chr20:30,603,701...30,626,835
Ensembl chr20:31,738,007...31,760,803 		JBrowse link
G C Ahcy adenosylhomocysteinase acts_upstream_of_or_within ISO (PMID:12023972) RGD
MGI		 PMID:11741948 PMID:12023972 RGD:730275 NCBI chrNW_004955422:26,992,295...27,013,100
Ensembl chrNW_004955422:26,992,295...27,013,100 		JBrowse link
G R Ahcy adenosylhomocysteinase acts_upstream_of_or_within IDA
ISO		 (PMID:12023972) RGD PMID:12023972 PMID:11741948 RGD:730275 NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393 		JBrowse link
G M Ahcy S-adenosylhomocysteine hydrolase acts_upstream_of_or_within
involved_in		 ISO
IDA		 (PMID:12023972) RGD
MGI		 PMID:11741948 PMID:12023972 GO_REF:0000096 MGI:4417868 RGD:730275 NCBI chr 2:154,901,230...154,916,417
Ensembl chr 2:154,901,230...154,916,417 		JBrowse link
G H AHCY adenosylhomocysteinase acts_upstream_of_or_within ISO (PMID:12023972) RGD
MGI		 PMID:11741948 PMID:12023972 RGD:730275 NCBI chr20:34,231,981...34,311,836
Ensembl chr20:34,280,268...34,311,802 		JBrowse link
G M Ahcyl adenosylhomocysteinase like involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr16:45,973,348...45,975,440
Ensembl chr16:45,973,348...45,975,440 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 180412
    metabolic process 103348
      cellular metabolic process 86444
        sulfur compound metabolic process 3081
          S-adenosylhomocysteine metabolic process 62
            S-adenosylhomocysteine catabolic process 11
Path 2
Term Annotations click to browse term
  biological_process 180412
    metabolic process 103348
      organic substance metabolic process 99029
        organic cyclic compound metabolic process 55897
          nucleobase-containing compound metabolic process 51248
            nucleobase-containing small molecule metabolic process 6206
              nucleoside metabolic process 569
                ribonucleoside metabolic process 384
                  purine ribonucleoside metabolic process 289
                    S-adenosylhomocysteine metabolic process 62
                      S-adenosylhomocysteine catabolic process 11
paths to the root