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ONTOLOGY REPORT - ANNOTATIONS

Term:protein tyrosine kinase activator activity
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Accession:GO:0030296 term browser browse the term
Definition:Increases the activity of a protein tyrosine kinase, an enzyme which phosphorylates a tyrosyl phenolic group on a protein.


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protein tyrosine kinase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi1 abl-interactor 1 enables IEA
ISO		 GO_REF:0000107
(PMID:12672821)		 Ensembl
RGD		 PMID:12672821 GO_REF:0000107 NCBI chr17:85,098,837...85,179,829
Ensembl chr17:85,098,550...85,179,792 		JBrowse link
G Afap1l2 actin filament associated protein 1-like 2 enables ISO (PMID:17412687) RGD PMID:17412687 NCBI chr 1:255,964,238...256,060,828
Ensembl chr 1:255,964,238...256,060,820 		JBrowse link
G Cd24 CD24 molecule enables ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000118
PMID:11313396
(PMID:11313396)		 UniProt
GO_Central
TreeGrafter
RGD		 PMID:11313396 PMID:11313396 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118, RGD:8554536 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Egfr epidermal growth factor receptor enables ISO (PMID:11336639), (PMID:2176151) RGD PMID:2176151 PMID:11336639 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 enables ISO
IEA		 (PMID:7556068)
GO_REF:0000107		 RGD
Ensembl		 PMID:7556068 GO_REF:0000107 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor enables ISO (PMID:17626041) RGD PMID:17626041 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide enables ISS
ISO		 GO_REF:0000024
(PMID:15350694)		 UniProt
RGD		 PMID:15350694 GO_REF:0000024 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Grm5 glutamate metabotropic receptor 5 enables ISO
IGI		 (PMID:24012003) RGD PMID:24012003 PMID:24012003 RGD:8553716 NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A enables ISO (PMID:17720578) RGD PMID:17720578 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer enables IEA
ISO		 GO_REF:0000107
(PMID:12829785)
(PMID:19915009)		 Ensembl
RGD		 PMID:12829785 PMID:19915009 GO_REF:0000107 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Nrg1 neuregulin 1 enables ISO
IBA
IEA		 (PMID:7556068)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
(PMID:19632177), (PMID:8702723)		 RGD
GO_Central
TreeGrafter
Ensembl		 PMID:7556068 PMID:8702723 PMID:19632177 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 enables ISO (PMID:11121037) RGD PMID:11121037 NCBI chr11:68,707,940...68,768,816
Ensembl chr11:68,707,969...68,768,816 		JBrowse link
G Stap1 signal transducing adaptor family member 1 enables ISO (PMID:10518561) RGD PMID:10518561 NCBI chr14:21,950,466...21,981,395
Ensembl chr14:21,952,496...21,981,245 		JBrowse link
G Vldlr very low density lipoprotein receptor TAS RGD PMID:11854295 RGD:1342463 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920 		JBrowse link
receptor signaling protein tyrosine kinase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alk ALK receptor tyrosine kinase enables ISO (PMID:30061385), (PMID:34646012) RGD PMID:30061385 PMID:34646012 NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034 		JBrowse link
G Alkal1 ALK and LTK ligand 1 enables ISO
IBA		 (PMID:26418745), (PMID:34646012), (PMID:34819673)
GO_REF:0000033		 RGD
GO_Central		 PMID:26418745 PMID:34646012 PMID:34819673 GO_REF:0000033 NCBI chr 5:13,019,729...13,049,913
Ensembl chr 5:13,019,429...13,049,948 		JBrowse link
G Alkal2 ALK and LTK ligand 2 enables ISS
ISO
IBA		 GO_REF:0000024
(PMID:26418745), (PMID:30061385), (PMID:34646012), (PMID:34819673)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:26418745 PMID:30061385 PMID:34646012 PMID:34819673 GO_REF:0000024 GO_REF:0000033 NCBI chr 6:47,495,645...47,505,235
Ensembl chr 6:47,495,782...47,505,234 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 enables ISO (PMID:10488085) RGD PMID:10488085 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ltk leukocyte receptor tyrosine kinase enables ISO (PMID:30061385) RGD PMID:30061385 NCBI chr 3:106,734,675...106,741,552
Ensembl chr 3:106,734,676...106,743,369 		JBrowse link
transmembrane receptor protein tyrosine kinase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkal1 ALK and LTK ligand 1 enables ISO (PMID:34646012), (PMID:34819673) RGD PMID:34646012 PMID:34819673 NCBI chr 5:13,019,729...13,049,913
Ensembl chr 5:13,019,429...13,049,948 		JBrowse link
G Alkal2 ALK and LTK ligand 2 enables ISO (PMID:30061385), (PMID:34646012), (PMID:34819673) RGD PMID:30061385 PMID:34646012 PMID:34819673 NCBI chr 6:47,495,645...47,505,235
Ensembl chr 6:47,495,782...47,505,234 		JBrowse link
G Angpt4 angiopoietin 4 enables ISO (PMID:10051567), (PMID:15851516) RGD PMID:10051567 PMID:15851516 NCBI chr 3:140,420,389...140,454,213
Ensembl chr 3:140,420,389...140,453,583 		JBrowse link
G Areg amphiregulin enables ISO (PMID:8702723)
MGI:95294 (PMID:23086930), (PMID:23333074), (PMID:26243875), (PMID:30770250)		 RGD PMID:8702723 PMID:23086930 PMID:23333074 PMID:26243875 PMID:30770250 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Btc betacellulin enables ISO (PMID:12399441), (PMID:9168114)
MGI:95294 (PMID:18656477), (PMID:21897861), (PMID:8456283)		 RGD PMID:8456283 PMID:9168114 PMID:12399441 PMID:18656477 PMID:21897861 NCBI chr14:16,708,447...16,746,961
Ensembl chr14:16,707,982...16,747,049 		JBrowse link
G Dgkq diacylglycerol kinase, theta enables ISO UniProtKB:P01133 (PMID:22732145) RGD PMID:22732145 NCBI chr14:1,059,125...1,073,131
Ensembl chr14:1,059,170...1,073,131 		JBrowse link
G Egf epidermal growth factor enables ISO
IEA		 (PMID:11336639)
GO_REF:0000107
(PMID:11823423), (PMID:12761849), (PMID:14627991), (PMID:22822073), (PMID:6248866), (PMID:7752576), (PMID:9529375)		 RGD
Ensembl		 PMID:6248866 PMID:7752576 PMID:9529375 PMID:11336639 PMID:11823423 More... GO_REF:0000107 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor enables ISO (PMID:7678348) RGD PMID:7678348 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Epgn epithelial mitogen enables ISO MGI:95294 (PMID:11278323), (PMID:23899604), (PMID:24891618) RGD PMID:11278323 PMID:23899604 PMID:24891618 NCBI chr14:17,076,774...17,084,806
Ensembl chr14:17,076,774...17,084,806 		JBrowse link
G Ereg epiregulin enables ISO (PMID:28783046), (PMID:9556621)
MGI:95294 (PMID:28783046), (PMID:7706296)		 RGD PMID:7706296 PMID:9556621 PMID:28783046 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist enables ISO (MGI:4845816|PMID:20660291) RGD PMID:20660291 MGI:4845816 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor enables ISO (PMID:8702723)
MGI:2655703|MGI:2665039 (PMID:12621152), (PMID:16357442), (PMID:21946538)		 RGD PMID:8702723 PMID:12621152 PMID:16357442 PMID:21946538 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Igf1 insulin-like growth factor 1 enables ISO MGI:96433 (PMID:32697974), (PMID:35647546) RGD PMID:32697974 PMID:35647546 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf2 insulin-like growth factor 2 enables ISO MGI:96433 (PMID:29348399), (PMID:9281335) RGD PMID:9281335 PMID:29348399 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Ngf nerve growth factor enables ISO (MGI:5426777|PMID:19036963), (PMID:27655914) RGD PMID:19036963 PMID:27655914 MGI:5426777 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Tgfa transforming growth factor alpha enables IEA
ISO		 GO_REF:0000107
(PMID:7752576)		 Ensembl
RGD		 PMID:7752576 GO_REF:0000107 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894 		JBrowse link
G Vegfa vascular endothelial growth factor A enables ISO
IEA		 (PMID:20497126)
GO_REF:0000107		 RGD
Ensembl		 PMID:20497126 GO_REF:0000107 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21010
    molecular function regulator activity 2143
      enzyme regulator activity 1355
        enzyme activator activity 580
          kinase activator activity 152
            protein kinase activator activity 144
              protein tyrosine kinase activator activity 33
                receptor signaling protein tyrosine kinase activator activity 5
                transmembrane receptor protein tyrosine kinase activator activity 17
paths to the root