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ONTOLOGY REPORT - ANNOTATIONS

Term:transmembrane receptor protein tyrosine kinase activator activity
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Accession:GO:0030297 term browser browse the term
Definition:Binds to and increases the activity of a transmembrane receptor protein tyrosine kinase.


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transmembrane receptor protein tyrosine kinase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkal1 ALK and LTK ligand 1 enables ISO (PMID:34646012), (PMID:34819673) RGD PMID:34646012 PMID:34819673 NCBI chr 5:13,019,729...13,049,913
Ensembl chr 5:13,019,429...13,049,948 		JBrowse link
G Alkal2 ALK and LTK ligand 2 enables ISO (PMID:30061385), (PMID:34646012), (PMID:34819673) RGD PMID:30061385 PMID:34646012 PMID:34819673 NCBI chr 6:47,495,645...47,505,235
Ensembl chr 6:47,495,782...47,505,234 		JBrowse link
G Angpt4 angiopoietin 4 enables ISO (PMID:10051567), (PMID:15851516) RGD PMID:10051567 PMID:15851516 NCBI chr 3:140,420,389...140,454,213
Ensembl chr 3:140,420,389...140,453,583 		JBrowse link
G Areg amphiregulin enables ISO (PMID:8702723)
MGI:95294 (PMID:23086930), (PMID:23333074), (PMID:26243875), (PMID:30770250)		 RGD PMID:8702723 PMID:23086930 PMID:23333074 PMID:26243875 PMID:30770250 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Btc betacellulin enables ISO (PMID:12399441), (PMID:9168114)
MGI:95294 (PMID:18656477), (PMID:21897861), (PMID:8456283)		 RGD PMID:8456283 PMID:9168114 PMID:12399441 PMID:18656477 PMID:21897861 NCBI chr14:16,708,447...16,746,961
Ensembl chr14:16,707,982...16,747,049 		JBrowse link
G Dgkq diacylglycerol kinase, theta enables ISO UniProtKB:P01133 (PMID:22732145) RGD PMID:22732145 NCBI chr14:1,059,125...1,073,131
Ensembl chr14:1,059,170...1,073,131 		JBrowse link
G Egf epidermal growth factor enables ISO
IEA		 (PMID:11336639)
GO_REF:0000107
(PMID:11823423), (PMID:12761849), (PMID:14627991), (PMID:22822073), (PMID:6248866), (PMID:7752576), (PMID:9529375)		 RGD
Ensembl		 PMID:6248866 PMID:7752576 PMID:9529375 PMID:11336639 PMID:11823423 More... GO_REF:0000107 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor enables ISO (PMID:7678348) RGD PMID:7678348 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Epgn epithelial mitogen enables ISO MGI:95294 (PMID:11278323), (PMID:23899604), (PMID:24891618) RGD PMID:11278323 PMID:23899604 PMID:24891618 NCBI chr14:17,076,774...17,084,806
Ensembl chr14:17,076,774...17,084,806 		JBrowse link
G Ereg epiregulin enables ISO (PMID:28783046), (PMID:9556621)
MGI:95294 (PMID:28783046), (PMID:7706296)		 RGD PMID:7706296 PMID:9556621 PMID:28783046 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist enables ISO (MGI:4845816|PMID:20660291) RGD PMID:20660291 MGI:4845816 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor enables ISO (PMID:8702723)
MGI:2655703|MGI:2665039 (PMID:12621152), (PMID:16357442), (PMID:21946538)		 RGD PMID:8702723 PMID:12621152 PMID:16357442 PMID:21946538 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Igf1 insulin-like growth factor 1 enables ISO MGI:96433 (PMID:32697974), (PMID:35647546) RGD PMID:32697974 PMID:35647546 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf2 insulin-like growth factor 2 enables ISO MGI:96433 (PMID:29348399), (PMID:9281335) RGD PMID:9281335 PMID:29348399 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Ngf nerve growth factor enables ISO (MGI:5426777|PMID:19036963), (PMID:27655914) RGD PMID:19036963 PMID:27655914 MGI:5426777 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Tgfa transforming growth factor alpha enables IEA
ISO		 GO_REF:0000107
(PMID:7752576)		 Ensembl
RGD		 PMID:7752576 GO_REF:0000107 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894 		JBrowse link
G Vegfa vascular endothelial growth factor A enables ISO
IEA		 (PMID:20497126)
GO_REF:0000107		 RGD
Ensembl		 PMID:20497126 GO_REF:0000107 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21010
    molecular function regulator activity 2143
      signaling receptor regulator activity 544
        signaling receptor activator activity 503
          transmembrane receptor protein tyrosine kinase activator activity 17
Path 2
Term Annotations click to browse term
  molecular_function 21010
    molecular function regulator activity 2143
      enzyme regulator activity 1355
        enzyme activator activity 580
          kinase activator activity 152
            protein kinase activator activity 144
              protein tyrosine kinase activator activity 33
                transmembrane receptor protein tyrosine kinase activator activity 17
paths to the root