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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of circadian rhythm
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Accession:GO:0042752 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.

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regulation of circadian rhythm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY1 adenylate cyclase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:12,976,687...13,117,876
Ensembl chr21:12,979,033...13,117,730 		JBrowse link
G ATG7 autophagy related 7 involved_in ISO (MGI:6208175|PMID:29937374) UniProt PMID:29937374 MGI:6208175 NCBI chr22:47,187,305...47,571,309
Ensembl chr22:47,325,614...47,571,070 		JBrowse link
G BHLHE40 basic helix-loop-helix family member e40 involved_in ISO (MGI:6282958|PMID:30012868) UniProt PMID:30012868 MGI:6282958 NCBI chr22:41,049,673...41,055,365
Ensembl chr22:41,049,712...41,055,360 		JBrowse link
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase involved_in ISO (PMID:15917222) UniProt PMID:15917222 NCBI chr 9:94,333,046...94,581,327
Ensembl chr 9:94,376,055...94,574,678 		JBrowse link
G CCAR2 cell cycle and apoptosis regulator 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:20,685,482...20,700,424
Ensembl chr 8:20,686,504...20,699,707 		JBrowse link
G CDK1 cyclin dependent kinase 1 involved_in ISO (PMID:27238018) UniProt PMID:27238018 NCBI chr 9:70,475,736...70,492,947 JBrowse link
G CLOCK clock circadian regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:13,015,198...13,134,741
Ensembl chr 7:13,051,454...13,127,240 		JBrowse link
G CRY1 cryptochrome circadian regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:102,200,822...102,306,165
Ensembl chr11:102,204,224...102,306,182 		JBrowse link
G CRY2 cryptochrome circadian regulator 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:19,459,734...19,498,807
Ensembl chr 1:19,472,231...19,498,790 		JBrowse link
G CSNK1D casein kinase 1 delta involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:74,157,875...74,192,142
Ensembl chr16:74,160,648...74,192,108 		JBrowse link
G DDB1 damage specific DNA binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:12,508,712...12,543,127
Ensembl chr 1:12,508,443...12,544,913 		JBrowse link
G DRD4 dopamine receptor D4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:454,018...459,582 JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:117,380,518...117,515,224
Ensembl chr21:117,380,361...117,421,573 		JBrowse link
G FBXL3 F-box and leucine rich repeat protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:56,089,147...56,111,472
Ensembl chr 3:56,088,938...56,105,977 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:98,894,261...99,105,955
Ensembl chr 7:98,892,504...99,106,084 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta involved_in ISO (MGI:6294161|PMID:28556462) UniProt PMID:28556462 MGI:6294161 NCBI chr22:60,732,449...61,002,735
Ensembl chr22:60,733,465...60,997,239 		JBrowse link
G HDAC3 histone deacetylase 3 involved_in ISO (MGI:5882311|PMID:26776516) UniProt PMID:26776516 MGI:5882311 NCBI chr23:44,246,296...44,263,127 JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:19,390,870...19,466,300
Ensembl chr 2:19,388,891...19,421,664 		JBrowse link
G HNRNPD heterogeneous nuclear ribonucleoprotein D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:30,729,697...30,749,793
Ensembl chr 7:30,731,175...30,749,876 		JBrowse link
G ID2 inhibitor of DNA binding 2 involved_in ISO (MGI:3838062|PMID:19217292) UniProt PMID:19217292 MGI:3838062 NCBI chr14:98,962,001...98,964,486 JBrowse link
G KDM2A lysine demethylase 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:7,004,109...7,152,072
Ensembl chr 1:7,003,784...7,082,720 		JBrowse link
G KLF10 KLF transcription factor 10 involved_in ISO PMID:20070857 UniProt PMID:20070857 RGD:10047352 NCBI chr 8:97,496,695...97,503,818
Ensembl chr 8:97,496,678...97,503,620 		JBrowse link
G LOC103223312 casein kinase I involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:20,992,927...21,025,866
Ensembl chr19:20,998,009...21,022,576 		JBrowse link
G LOC103223491 peroxisome proliferator-activated receptor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:28,614,892...28,709,272
Ensembl chr19:28,615,413...28,708,763 		JBrowse link
G MAGED1 MAGE family member D1 involved_in ISO (MGI:5508569|PMID:20300063) UniProt PMID:20300063 MGI:5508569 NCBI chr  X:48,523,139...48,629,837
Ensembl chr  X:48,621,533...48,630,306 		JBrowse link
G MAGEL2 MAGE family member L2 involved_in ISO (MGI:5607219|PMID:22208286) UniProt PMID:22208286 MGI:5607219 NCBI chr26:57,975,936...57,980,492 JBrowse link
G MAPK10 mitogen-activated protein kinase 10 involved_in ISO (MGI:5431019|PMID:22441692) UniProt PMID:22441692 MGI:5431019 NCBI chr 7:34,394,600...34,725,658
Ensembl chr 7:34,399,544...34,564,212 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 involved_in ISO (MGI:5431019|PMID:22441692) UniProt PMID:22441692 MGI:5431019 NCBI chr 9:43,356,603...43,489,066
Ensembl chr 9:43,356,308...43,393,425 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 involved_in ISO (MGI:5431019|PMID:22441692) UniProt PMID:22441692 MGI:5431019 NCBI chr23:81,965,330...82,026,414
Ensembl chr23:81,963,899...82,013,659 		JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:120,522,667...120,678,988
Ensembl chr20:120,525,737...120,679,020 		JBrowse link
G NOCT nocturnin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:85,987,854...86,019,271
Ensembl chr 7:86,015,576...86,018,474 		JBrowse link
G NONO non-POU domain containing octamer binding involved_in ISO (MGI:5444785|PMID:22966205) UniProt PMID:22966205 MGI:5444785 NCBI chr  X:61,082,923...61,110,895 JBrowse link
G NPAS2 neuronal PAS domain protein 2 involved_in ISO (MGI:5518489|PMID:24048828) UniProt PMID:24048828 MGI:5518489 NCBI chr14:4,529,048...4,705,167
Ensembl chr14:4,612,225...4,705,419 		JBrowse link
G NR1D1 nuclear receptor subfamily 1 group D member 1 involved_in ISO (MGI:4360821|PMID:19721697), (MGI:4429726|PMID:20159955), (MGI:6162161|PMID:29533925)
PMID:22425774		 UniProt PMID:19721697 PMID:20159955 PMID:22425774 PMID:29533925 MGI:4360821 MGI:4429726 MGI:6162161 RGD:8553819 NCBI chr16:66,078,990...66,086,927
Ensembl chr16:66,079,089...66,090,685 		JBrowse link
G NR1D2 nuclear receptor subfamily 1 group D member 2 involved_in ISO (MGI:6162161|PMID:29533925)
(MGI:5526909|PMID:23221024)		 UniProt PMID:23221024 PMID:29533925 MGI:5526909 MGI:6162161 NCBI chr15:68,632,142...68,668,467
Ensembl chr15:68,632,197...68,665,258 		JBrowse link
G OPN4 opsin 4 involved_in ISO (MGI:2667269|PMID:12808468) UniProt PMID:12808468 MGI:2667269 NCBI chr 9:45,199,897...45,212,193
Ensembl chr 9:45,200,707...45,211,636 		JBrowse link
G PER1 period circadian regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:7,520,122...7,536,176
Ensembl chr16:7,520,006...7,531,940 		JBrowse link
G PER2 period circadian regulator 2 involved_in ISO (MGI:1935010|PMID:11395012), (MGI:4410390|PMID:19917250) UniProt PMID:11395012 PMID:19917250 MGI:1935010 MGI:4410390 NCBI chr10:124,270,917...124,316,031
Ensembl chr10:124,269,543...124,315,904 		JBrowse link
G PML PML nuclear body scaffold involved_in ISO (MGI:5314433|PMID:22274616) UniProt PMID:22274616 MGI:5314433 NCBI chr26:9,441,998...9,494,949
Ensembl chr26:9,451,112...9,494,931 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma involved_in ISO (MGI:3830801|PMID:19041764) UniProt PMID:19041764 MGI:3830801 NCBI chr22:48,262,743...48,407,415
Ensembl chr22:48,275,600...48,407,418 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:25,882,385...26,563,530
Ensembl chr27:26,465,499...26,564,582 		JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:6,862,536...6,866,212
Ensembl chr 1:6,862,540...6,865,855 		JBrowse link
G PPP1CB protein phosphatase 1 catalytic subunit beta involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr14:78,802,295...78,852,683
Ensembl chr14:78,804,548...78,852,682 		JBrowse link
G PPP1CC protein phosphatase 1 catalytic subunit gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:105,962,182...105,986,114 JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:39,516,307...39,553,627 JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:76,258,063...76,319,512
Ensembl chr20:76,259,763...76,319,430 		JBrowse link
G PRKCG protein kinase C gamma involved_in ISO (MGI:5467682|PMID:23185022) UniProt PMID:23185022 MGI:5467682 NCBI chr 6:46,574,560...46,600,329
Ensembl chr 6:46,575,439...46,600,364 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:43,915,226...44,119,547
Ensembl chr 8:43,914,636...44,119,541 		JBrowse link
G PROX1 prospero homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:15,533,546...15,592,834
Ensembl chr25:15,538,964...15,587,059 		JBrowse link
G PSPC1 paraspeckle component 1 involved_in ISO (MGI:5444785|PMID:22966205) UniProt PMID:22966205 MGI:5444785 NCBI chr 3:1,160,227...1,232,390 JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 involved_in ISO (PMID:23172836)
(MGI:5567901|PMID:23172836)		 UniProt PMID:23172836 MGI:5567901 NCBI chr14:96,275,889...96,443,048
Ensembl chr14:96,276,023...96,432,790 		JBrowse link
G RORA RAR related orphan receptor A involved_in ISO (MGI:5567901|PMID:23172836) UniProt PMID:23172836 MGI:5567901 NCBI chr26:22,263,889...23,002,224
Ensembl chr26:22,812,445...22,993,021 		JBrowse link
G RORB RAR related orphan receptor B involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:85,545,609...85,735,804
Ensembl chr12:85,545,608...85,732,780 		JBrowse link
G SFPQ splicing factor proline and glutamine rich involved_in ISO (MGI:5444785|PMID:22966205) UniProt PMID:22966205 MGI:5444785 NCBI chr20:97,698,953...97,715,762
Ensembl chr20:97,698,411...97,711,294 		JBrowse link
G SIAH2 siah E3 ubiquitin protein ligase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:39,939,209...39,960,750
Ensembl chr15:39,939,832...39,959,734 		JBrowse link
G SIRT6 sirtuin 6 involved_in ISO (MGI:6443593|PMID:30782483) UniProt PMID:30782483 MGI:6443593 NCBI chr 6:3,924,230...3,932,583
Ensembl chr 6:3,924,230...3,932,590 		JBrowse link
G SPSB4 splA/ryanodine receptor domain and SOCS box containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:49,442,817...49,529,654
Ensembl chr15:49,442,864...49,515,357 		JBrowse link
G SRRD SRR1 domain containing involved_in ISO (MGI:6282940|PMID:28802827) UniProt PMID:28802827 MGI:6282940 NCBI chr19:9,387,861...9,396,219
Ensembl chr19:9,387,648...9,395,955 		JBrowse link
G TARDBP TAR DNA binding protein involved_in ISO (MGI:6253084|PMID:27123980) UniProt PMID:27123980 MGI:6253084 NCBI chr20:120,753,764...120,765,259 JBrowse link
G TIMELESS timeless circadian regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:52,371,781...52,408,923
Ensembl chr11:52,372,375...52,389,284 		JBrowse link
G TOP2A DNA topoisomerase II alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:65,761,391...65,792,041
Ensembl chr16:65,761,416...65,792,701 		JBrowse link
G UBE3A ubiquitin protein ligase E3A involved_in ISO (MGI:5607382|PMID:24728990)
(PMID:24728990)		 UniProt PMID:24728990 MGI:5607382 NCBI chr26:56,638,936...56,738,555
Ensembl chr26:56,666,162...56,736,737 		JBrowse link
G USP7 ubiquitin specific peptidase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:8,470,137...8,540,736
Ensembl chr 5:8,469,230...8,540,770 		JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked involved_in ISO (PMID:29626158) UniProt PMID:29626158 NCBI chr  X:38,255,414...38,402,855
Ensembl chr  X:38,256,008...38,403,323
Ensembl chr  Y:38,256,008...38,403,323 		JBrowse link
entrainment of circadian clock term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATOH7 atonal bHLH transcription factor 7 acts_upstream_of_or_within ISO (PMID:12451142) MGI PMID:12451142 NCBI chr 9:63,155,182...63,158,935
Ensembl chr 9:63,157,638...63,158,096 		JBrowse link
G CHRM1 cholinergic receptor muscarinic 1 involved_in ISS AgBase GO_REF:0000024 NCBI chr 1:10,978,464...10,991,650
Ensembl chr 1:10,989,207...10,990,589 		JBrowse link
G CLOCK clock circadian regulator ISO RGD PMID:10095082 RGD:632379 NCBI chr 7:13,015,198...13,134,741
Ensembl chr 7:13,051,454...13,127,240 		JBrowse link
G ID2 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO (PMID:19217292) MGI PMID:19217292 NCBI chr14:98,962,001...98,964,486 JBrowse link
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 acts_upstream_of_or_within ISO (PMID:20080691) MGI PMID:20080691 NCBI chr18:16,786,128...17,051,250 JBrowse link
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr18:16,785,503...17,049,752 JBrowse link
G SOX14 SRY-box transcription factor 14 acts_upstream_of_or_within ISO (PMID:22920256) MGI PMID:22920256 NCBI chr15:52,749,639...52,766,770
Ensembl chr15:52,762,326...52,763,045 		JBrowse link
G TIMELESS timeless circadian regulator involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:52,371,781...52,408,923
Ensembl chr11:52,372,375...52,389,284 		JBrowse link
entrainment of circadian clock by photoperiod term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATOH7 atonal bHLH transcription factor 7 involved_in ISO (MGI:5699646|PMID:26392540) UniProt PMID:26392540 MGI:5699646 NCBI chr 9:63,155,182...63,158,935
Ensembl chr 9:63,157,638...63,158,096 		JBrowse link
G BHLHE40 basic helix-loop-helix family member e40 involved_in ISO (MGI:3798698|PMID:18411297) BHF-UCL PMID:18411297 MGI:3798698 NCBI chr22:41,049,673...41,055,365
Ensembl chr22:41,049,712...41,055,360 		JBrowse link
G CRTC1 CREB regulated transcription coactivator 1 involved_in ISO (MGI:5532783|PMID:23993098) UniProt PMID:23993098 MGI:5532783 NCBI chr 6:17,146,954...17,246,209 JBrowse link
G CRY1 cryptochrome circadian regulator 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:102,200,822...102,306,165
Ensembl chr11:102,204,224...102,306,182 		JBrowse link
G CRY2 cryptochrome circadian regulator 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:19,459,734...19,498,807
Ensembl chr 1:19,472,231...19,498,790 		JBrowse link
G FBXL21P F-box and leucine rich repeat protein 21 involved_in ISO (MGI:5470183|PMID:23452855), (MGI:5487698|PMID:23452856) UniProt PMID:23452855 PMID:23452856 MGI:5470183 MGI:5487698 NCBI chr23:38,680,722...38,692,592 JBrowse link
G FBXL3 F-box and leucine rich repeat protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:56,089,147...56,111,472
Ensembl chr 3:56,088,938...56,105,977 		JBrowse link
G ID2 inhibitor of DNA binding 2 involved_in ISO (MGI:3838062|PMID:19217292) UniProt PMID:19217292 MGI:3838062 NCBI chr14:98,962,001...98,964,486 JBrowse link
G LOC103219558 serine/threonine-protein kinase SIK1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:87,204,386...87,217,044
Ensembl chr 2:87,204,357...87,216,180 		JBrowse link
G LOC103221203 RNA-binding protein 4 involved_in ISO (MGI:3703208|PMID:17264215) UniProt PMID:17264215 MGI:3703208 NCBI chr 1:7,604,440...7,638,536 JBrowse link
G LOC103221444 RNA-binding protein 4B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:7,594,565...7,607,824
Ensembl chr 1:7,594,677...7,604,199 		JBrowse link
G MTA1 metastasis associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:83,315,917...83,368,746 JBrowse link
G NR2F6 nuclear receptor subfamily 2 group F member 6 acts_upstream_of_or_within ISO (PMID:15741322) MGI PMID:15741322 NCBI chr 6:15,728,489...15,753,019
Ensembl chr 6:15,725,021...15,753,171 		JBrowse link
G OPN5 opsin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:24,478,464...24,509,720
Ensembl chr17:24,478,672...24,508,814 		JBrowse link
G PDE6B phosphodiesterase 6B involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:48,117,495...48,168,727
Ensembl chr27:48,118,190...48,162,368 		JBrowse link
G PER1 period circadian regulator 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:7,520,122...7,536,176
Ensembl chr16:7,520,006...7,531,940 		JBrowse link
G PER2 period circadian regulator 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:124,270,917...124,316,031
Ensembl chr10:124,269,543...124,315,904 		JBrowse link
G PER3 period circadian regulator 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:123,912,773...123,970,440
Ensembl chr20:123,912,208...123,970,549 		JBrowse link
G PML PML nuclear body scaffold involved_in ISO (MGI:5314433|PMID:22274616) UniProt PMID:22274616 MGI:5314433 NCBI chr26:9,441,998...9,494,949
Ensembl chr26:9,451,112...9,494,931 		JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:6,862,536...6,866,212
Ensembl chr 1:6,862,540...6,865,855 		JBrowse link
G PPP1CB protein phosphatase 1 catalytic subunit beta involved_in ISO (MGI:5086036|PMID:21712997) UniProt PMID:21712997 MGI:5086036 NCBI chr14:78,802,295...78,852,683
Ensembl chr14:78,804,548...78,852,682 		JBrowse link
G PPP1CC protein phosphatase 1 catalytic subunit gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:105,962,182...105,986,114 JBrowse link
G TP53 tumor protein p53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223 		JBrowse link
G USP2 ubiquitin specific peptidase 2 involved_in ISO (MGI:5607210|PMID:23213472) UniProt PMID:23213472 MGI:5607210 NCBI chr 1:110,733,097...110,760,119
Ensembl chr 1:110,734,737...110,742,186 		JBrowse link
negative regulation of circadian rhythm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CIPC CLOCK interacting pacemaker involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr24:54,341,807...54,360,949
Ensembl chr24:54,349,341...54,357,937 		JBrowse link
G CRY1 cryptochrome circadian regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:102,200,822...102,306,165
Ensembl chr11:102,204,224...102,306,182 		JBrowse link
G CRY2 cryptochrome circadian regulator 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:19,459,734...19,498,807
Ensembl chr 1:19,472,231...19,498,790 		JBrowse link
G PASD1 PAS domain containing repressor 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:126,154,328...126,221,997
Ensembl chr  X:126,157,638...126,221,988 		JBrowse link
G PER2 period circadian regulator 2 involved_in ISO (MGI:4410413|PMID:19605937) UniProt PMID:19605937 MGI:4410413 NCBI chr10:124,270,917...124,316,031
Ensembl chr10:124,269,543...124,315,904 		JBrowse link
G PIWIL2 piwi like RNA-mediated gene silencing 2 involved_in ISO (MGI:6285118|PMID:28903391)
(PMID:28903391)		 UniProt PMID:28903391 MGI:6285118 NCBI chr 8:20,347,998...20,436,016
Ensembl chr 8:20,352,771...20,433,947 		JBrowse link
G SFPQ splicing factor proline and glutamine rich involved_in ISO (MGI:5014424|PMID:21680841) UniProt PMID:21680841 MGI:5014424 NCBI chr20:97,698,953...97,715,762
Ensembl chr20:97,698,411...97,711,294 		JBrowse link
G SIN3A SIN3 transcription regulator family member A involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:7,971,208...8,060,888
Ensembl chr26:7,975,484...8,058,278 		JBrowse link
negative regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase ISO RGD PMID:19066225 RGD:5128864 NCBI chr 2:19,167,209...19,200,233 JBrowse link
G ADORA1 adenosine A1 receptor ISO RGD PMID:19491711 RGD:2317916 NCBI chr25:26,180,898...26,221,424
Ensembl chr25:26,182,446...26,220,776 		JBrowse link
negative regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRL ghrelin and obestatin prepropeptide involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:46,326,458...46,332,906
Ensembl chr22:46,325,913...46,330,962 		JBrowse link
negative regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA1 adenosine A1 receptor ISO in the sleep-promoting area of the lateral preoptic area of the brain RGD PMID:16109808 RGD:1625234 NCBI chr25:26,180,898...26,221,424
Ensembl chr25:26,182,446...26,220,776 		JBrowse link
G DRD1 dopamine receptor D1 ISO RGD PMID:12944496 RGD:1581422 NCBI chr23:77,587,340...77,591,434 JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:12944496 RGD:1581422 NCBI chr 1:104,774,632...104,843,417
Ensembl chr 1:104,774,180...104,842,736 		JBrowse link
negative regulation of circadian sleep/wake cycle, wakefulness term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:10923657 RGD:10043386 NCBI chr20:62,093,830...62,293,360
Ensembl chr20:62,095,458...62,174,959 		JBrowse link
negative regulation of locomotor rhythm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LEPR leptin receptor ISO RGD PMID:16982424 RGD:10412019 NCBI chr20:67,454,205...67,567,524
Ensembl chr20:67,454,334...67,524,229 		JBrowse link
positive regulation of circadian rhythm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMAL1 basic helix-loop-helix ARNT like 1 involved_in ISO (PMID:23229515)
(MGI:4410413|PMID:19605937), (MGI:5442460|PMID:22653727)		 ComplexPortal PMID:19605937 PMID:22653727 PMID:23229515 MGI:4410413 MGI:5442460 NCBI chr 1:51,430,670...51,540,344
Ensembl chr 1:51,431,180...51,462,674 		JBrowse link
G BMAL2 basic helix-loop-helix ARNT like 2 involved_in ISO (PMID:12738229)
(MGI:4410413|PMID:19605937)		 ComplexPortal
UniProt		 PMID:12738229 PMID:19605937 MGI:4410413 NCBI chr11:27,067,523...27,141,740
Ensembl chr11:27,067,604...27,136,466 		JBrowse link
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase involved_in ISO (MGI:4844267|PMID:18782782) UniProt PMID:18782782 MGI:4844267 NCBI chr 9:94,333,046...94,581,327
Ensembl chr 9:94,376,055...94,574,678 		JBrowse link
G CLOCK clock circadian regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:13,015,198...13,134,741
Ensembl chr 7:13,051,454...13,127,240 		JBrowse link
G FBXW11 F-box and WD repeat domain containing 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:74,015,964...74,154,285
Ensembl chr23:74,015,964...74,154,062 		JBrowse link
G KAT5 lysine acetyltransferase 5 involved_in ISO (MGI:6331398|PMID:31294688) UniProt PMID:31294688 MGI:6331398 NCBI chr 1:8,528,097...8,544,512
Ensembl chr 1:8,526,788...8,544,972 		JBrowse link
G MTNR1B melatonin receptor 1B ISO RGD PMID:12643943 RGD:9588678 NCBI chr 1:84,222,150...84,238,850
Ensembl chr 1:84,223,147...84,235,463 		JBrowse link
G NKX2-1 NK2 homeobox 1 involved_in ISO (MGI:5574291|PMID:22356123) UniProt PMID:22356123 MGI:5574291 NCBI chr24:13,274,118...13,317,533
Ensembl chr24:13,310,846...13,317,056 		JBrowse link
G NR1D1 nuclear receptor subfamily 1 group D member 1 ISO RGD PMID:18946026 RGD:10448985 NCBI chr16:66,078,990...66,086,927
Ensembl chr16:66,079,089...66,090,685 		JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 ISO RGD PMID:12930792 RGD:7777105 NCBI chr 9:78,858,269...80,188,163 JBrowse link
G RORA RAR related orphan receptor A involved_in ISO (MGI:5504349|PMID:22753030) UniProt PMID:22753030 MGI:5504349 NCBI chr26:22,263,889...23,002,224
Ensembl chr26:22,812,445...22,993,021 		JBrowse link
G RORC RAR related orphan receptor C involved_in ISO (MGI:5504349|PMID:22753030) UniProt PMID:22753030 MGI:5504349 NCBI chr20:11,854,911...11,880,221
Ensembl chr20:11,855,005...11,879,717 		JBrowse link
G THRAP3 thyroid hormone receptor associated protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:96,552,233...96,631,220
Ensembl chr20:96,552,077...96,599,904 		JBrowse link
G TIMELESS timeless circadian regulator ISO RGD PMID:14564007 RGD:734503 NCBI chr11:52,371,781...52,408,923
Ensembl chr11:52,372,375...52,389,284 		JBrowse link
positive regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALB albumin ISO RGD PMID:9748091 RGD:1625449 NCBI chr 7:21,872,036...21,890,095
Ensembl chr 7:21,876,132...21,891,407 		JBrowse link
G CASP1 caspase 1 ISO RGD PMID:16455762 RGD:2315921 NCBI chr 1:96,389,697...96,400,610
Ensembl chr 1:96,389,657...96,400,849 		JBrowse link
G GHRH growth hormone releasing hormone ISO RGD PMID:19889861 PMID:20237285 RGD:10401262 RGD:2325188 NCBI chr 2:26,482,734...26,493,761
Ensembl chr 2:26,487,973...26,493,499 		JBrowse link
G GHRHR growth hormone releasing hormone receptor ISO RGD PMID:20237285 RGD:10401262 NCBI chr21:27,402,765...27,417,536
Ensembl chr21:27,404,886...27,417,521 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:46,326,458...46,332,906
Ensembl chr22:46,325,913...46,330,962 		JBrowse link
G MTNR1B melatonin receptor 1B ISO RGD PMID:19429170 PMID:22171046 RGD:9588660 RGD:9588665 NCBI chr 1:84,222,150...84,238,850
Ensembl chr 1:84,223,147...84,235,463 		JBrowse link
G NPY2R neuropeptide Y receptor Y2 ISO RGD PMID:16378653 RGD:1642507 NCBI chr 7:101,696,081...101,773,782
Ensembl chr 7:101,770,551...101,771,696 		JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:10923657 RGD:10043386 NCBI chr20:62,093,830...62,293,360
Ensembl chr20:62,095,458...62,174,959 		JBrowse link
G PTGER4 prostaglandin E receptor 4 ISO RGD PMID:10923657 RGD:10043386 NCBI chr 4:39,440,697...39,453,983
Ensembl chr 4:39,440,276...39,454,004 		JBrowse link
positive regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRH growth hormone releasing hormone NOT|involved_in ISO (PMID:15538933) BHF-UCL PMID:15538933 NCBI chr 2:26,482,734...26,493,761
Ensembl chr 2:26,487,973...26,493,499 		JBrowse link
G PMCH pro-melanin concentrating hormone ISO RGD PMID:12964948 RGD:1642489 NCBI chr11:97,436,682...97,438,345 JBrowse link
G UTS2 urotensin 2 ISO RGD PMID:15944374 RGD:2306844 NCBI chr20:123,903,137...123,910,180 JBrowse link
G UTS2R urotensin 2 receptor ISO RGD PMID:15944374 RGD:2306844 NCBI chr16:74,284,472...74,291,074
Ensembl chr16:74,288,333...74,289,502 		JBrowse link
positive regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2A adenosine A2a receptor ISO in the sleep-promoting area of the lateral preoptic area of the brain RGD PMID:16109808 RGD:1625234 NCBI chr19:7,691,678...7,706,781
Ensembl chr19:7,691,536...7,706,926 		JBrowse link
positive regulation of circadian sleep/wake cycle, wakefulness term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NLGN1 neuroligin 1 involved_in ISO (MGI:5492265|PMID:23716671) UniProt PMID:23716671 MGI:5492265 NCBI chr15:15,129,976...16,017,107 JBrowse link
G NLGN1 neuroligin 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr15:15,131,866...15,141,276 JBrowse link
G NPS neuropeptide S ISO RGD PMID:22300983 RGD:9831203 NCBI chr 9:120,168,749...120,176,288 JBrowse link
G UTS2 urotensin 2 ISO RGD PMID:15944374 RGD:2306844 NCBI chr20:123,903,137...123,910,180 JBrowse link
G UTS2R urotensin 2 receptor ISO RGD PMID:15944374 RGD:2306844 NCBI chr16:74,284,472...74,291,074
Ensembl chr16:74,288,333...74,289,502 		JBrowse link
regulation of circadian sleep/wake cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR1D1 nuclear receptor subfamily 1 group D member 1 involved_in ISO (MGI:6283959|PMID:30792350) UniProt PMID:30792350 MGI:6283959 NCBI chr16:66,078,990...66,086,927
Ensembl chr16:66,079,089...66,090,685 		JBrowse link
regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO (PMID:15215293) MGI PMID:15215293 NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795 		JBrowse link
G IL6 interleukin 6 ISO RGD PMID:12667648 RGD:1358315 NCBI chr21:35,577,513...35,582,385
Ensembl chr21:35,577,939...35,582,237 		JBrowse link
G KCNA2 potassium voltage-gated channel subfamily A member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:22,933,524...22,942,074
Ensembl chr20:22,940,154...22,941,650 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in ISO (MGI:6874638|PMID:34798058) UniProt PMID:34798058 MGI:6874638 NCBI chr25:3,350,798...3,405,040 JBrowse link
regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO (PMID:15215293) MGI PMID:15215293 NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795 		JBrowse link
regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase ISO RGD PMID:11038259 RGD:631747 NCBI chr 2:19,167,209...19,200,233 JBrowse link
G ADRB1 adrenoceptor beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:106,920,520...106,923,424
Ensembl chr 9:106,920,610...106,922,058 		JBrowse link
G CSF2 colony stimulating factor 2 ISO RGD PMID:12047622 RGD:10449529 NCBI chr23:34,906,987...34,911,252
Ensembl chr23:34,908,911...34,911,140 		JBrowse link
G DRD3 dopamine receptor D3 ISO RGD PMID:15913875 RGD:1625069 NCBI chr22:66,683,987...66,737,645
Ensembl chr22:66,691,177...66,736,690 		JBrowse link
G FXR1 FMR1 autosomal homolog 1 involved_in ISO (MGI:6706222|PMID:32893934) UniProt PMID:32893934 MGI:6706222 NCBI chr15:8,420,789...8,486,681
Ensembl chr15:8,421,654...8,486,384 		JBrowse link
G NMU neuromedin U involved_in ISO PMID:20233222 UniProt PMID:20233222 RGD:12911001 NCBI chr 7:12,931,176...12,967,294
Ensembl chr 7:12,932,226...12,962,741 		JBrowse link
G PER3 period circadian regulator 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:123,912,773...123,970,440
Ensembl chr20:123,912,208...123,970,549 		JBrowse link
G PGLYRP1 peptidoglycan recognition protein 1 ISO RGD PMID:11145837 RGD:724610 NCBI chr 6:39,474,077...39,478,635
Ensembl chr 6:39,474,170...39,477,914 		JBrowse link
G PTGDS prostaglandin D2 synthase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,210,567...1,214,631
Ensembl chr12:1,211,487...1,214,531 		JBrowse link
regulation of circadian sleep/wake cycle, wakefulness term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HCRTR2 hypocretin receptor 2 involved_in ISO (PMID:11282968) UniProt PMID:11282968 NCBI chr17:16,258,262...16,371,576
Ensembl chr17:16,258,439...16,294,204 		JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:10923657 RGD:10043386 NCBI chr20:62,093,830...62,293,360
Ensembl chr20:62,095,458...62,174,959 		JBrowse link
G PTGER4 prostaglandin E receptor 4 ISO RGD PMID:10923657 RGD:10043386 NCBI chr 4:39,440,697...39,453,983
Ensembl chr 4:39,440,276...39,454,004 		JBrowse link
regulation of locomotor rhythm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTOR mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:120,522,667...120,678,988
Ensembl chr20:120,525,737...120,679,020 		JBrowse link
G ZFHX3 zinc finger homeobox 3 involved_in ISO (MGI:5660827|PMID:26232227) UniProt PMID:26232227 MGI:5660827 NCBI chr 5:55,912,325...56,174,010
Ensembl chr 5:55,907,983...56,085,112 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16925
    regulation of biological process 11245
      regulation of circadian rhythm 127
        entrainment of circadian clock + 30
        negative regulation of circadian rhythm + 15
        positive regulation of circadian rhythm + 29
        regulation of circadian sleep/wake cycle + 34
        regulation of locomotor rhythm + 3
        temperature compensation of the circadian clock 0
Path 2
Term Annotations click to browse term
  biological_process 16925
    rhythmic process 399
      circadian rhythm 272
        regulation of circadian rhythm 127
          entrainment of circadian clock + 30
          negative regulation of circadian rhythm + 15
          positive regulation of circadian rhythm + 29
          regulation of circadian sleep/wake cycle + 34
          regulation of locomotor rhythm + 3
          temperature compensation of the circadian clock 0
paths to the root