PIWIL2 (piwi like RNA-mediated gene silencing 2) - Rat Genome Database

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Gene: PIWIL2 (piwi like RNA-mediated gene silencing 2) Chlorocebus sabaeus
Analyze
Symbol: PIWIL2
Name: piwi like RNA-mediated gene silencing 2
RGD ID: 18642874
Description: ENCODES a protein that exhibits mRNA binding (ortholog); INVOLVED IN germ-line stem cell population maintenance (ortholog); negative regulation of circadian rhythm (ortholog); oogenesis (ortholog); ASSOCIATED WITH celiac disease (ortholog); Conotruncal Cardiac Defects (ortholog); FOUND IN chromatoid body (ortholog); dense body (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: piwi-like protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1820,347,998 - 20,436,016 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl820,352,771 - 20,433,947 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605221,799,635 - 21,889,513 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PIWIL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1820,347,998 - 20,436,016 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl820,352,771 - 20,433,947 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605221,799,635 - 21,889,513 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
PIWIL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38822,275,316 - 22,357,568 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl822,275,316 - 22,357,568 (+)EnsemblGRCh38hg38GRCh38
GRCh37822,132,829 - 22,215,081 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36822,188,796 - 22,269,545 (+)NCBINCBI36Build 36hg18NCBI36
Build 34822,188,800 - 22,269,529NCBI
Celera821,095,224 - 21,174,910 (+)NCBICelera
Cytogenetic Map8p21.3NCBI
HuRef820,675,010 - 20,755,706 (+)NCBIHuRef
CHM1_1822,334,485 - 22,415,561 (+)NCBICHM1_1
T2T-CHM13v2.0822,549,271 - 22,631,533 (+)NCBIT2T-CHM13v2.0
Piwil2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391470,609,926 - 70,674,338 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1470,609,926 - 70,666,832 (-)EnsemblGRCm39 Ensembl
GRCm381470,372,477 - 70,436,898 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1470,372,477 - 70,429,383 (-)EnsemblGRCm38mm10GRCm38
MGSCv371470,772,287 - 70,828,901 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361469,107,560 - 69,164,174 (-)NCBIMGSCv36mm8
Celera1467,913,743 - 67,970,583 (-)NCBICelera
Cytogenetic Map14D2NCBI
cM Map1436.32NCBI
Piwil2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81551,841,104 - 51,907,729 (-)NCBIGRCr8
mRatBN7.21545,431,402 - 45,498,034 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1545,431,703 - 45,497,702 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1549,549,570 - 49,615,564 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01550,661,059 - 50,727,061 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01547,520,373 - 47,586,368 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01552,037,693 - 52,116,277 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1552,037,693 - 52,116,001 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01555,760,496 - 55,839,763 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41550,757,820 - 50,823,943 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11550,775,399 - 50,839,987 (-)NCBI
Celera1545,111,291 - 45,176,770 (-)NCBICelera
Cytogenetic Map15p11NCBI
Piwil2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540345,737,674 - 45,819,873 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540345,737,674 - 45,819,478 (+)NCBIChiLan1.0ChiLan1.0
PIWIL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2740,777,023 - 40,865,972 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1816,502,223 - 16,591,180 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0821,520,166 - 21,608,374 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1818,459,052 - 18,546,688 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl818,463,173 - 18,544,186 (+)Ensemblpanpan1.1panPan2
PIWIL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12534,911,120 - 34,987,287 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2534,912,358 - 34,987,339 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2535,501,009 - 35,577,016 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02535,122,157 - 35,198,747 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2535,123,395 - 35,198,755 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12535,068,198 - 35,144,239 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02534,922,162 - 34,998,398 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02535,077,336 - 35,153,884 (-)NCBIUU_Cfam_GSD_1.0
Piwil2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494312,435,718 - 12,493,669 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365556,078,681 - 6,133,020 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365556,078,681 - 6,133,184 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIWIL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl146,560,565 - 6,632,523 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1146,560,402 - 6,632,524 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2146,994,765 - 7,064,683 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Piwil2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475817,834,191 - 17,902,575 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475817,834,268 - 17,911,886 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 2 2
Low 34 16 57
Below cutoff 4 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000014568   ⟹   ENSCSAP00000012537
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl820,352,771 - 20,433,947 (+)Ensembl
RefSeq Acc Id: XM_007961879   ⟹   XP_007960070
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1820,347,999 - 20,436,016 (+)NCBI
Vero_WHO_p1.0NW_02366605221,799,635 - 21,889,512 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007961880   ⟹   XP_007960071
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1820,348,755 - 20,436,016 (+)NCBI
Vero_WHO_p1.0NW_02366605221,800,691 - 21,887,517 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007961881   ⟹   XP_007960072
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1820,351,024 - 20,436,016 (+)NCBI
Vero_WHO_p1.0NW_02366605221,800,691 - 21,885,198 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007961883   ⟹   XP_007960074
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1820,347,999 - 20,436,016 (+)NCBI
Vero_WHO_p1.0NW_02366605221,801,138 - 21,889,513 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007961886   ⟹   XP_007960077
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1820,347,999 - 20,436,016 (+)NCBI
Vero_WHO_p1.0NW_02366605221,801,138 - 21,889,513 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007960070 (Get FASTA)   NCBI Sequence Viewer  
  XP_007960071 (Get FASTA)   NCBI Sequence Viewer  
  XP_007960072 (Get FASTA)   NCBI Sequence Viewer  
  XP_007960074 (Get FASTA)   NCBI Sequence Viewer  
  XP_007960077 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000012537.1
Reference Protein Sequences
RefSeq Acc Id: XP_007960070   ⟸   XM_007961879
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RV98 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007960077   ⟸   XM_007961886
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RV98 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007960074   ⟸   XM_007961883
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RV98 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007960071   ⟸   XM_007961880
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RV98 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007960072   ⟸   XM_007961881
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RV98 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000012537   ⟸   ENSCSAT00000014568


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000016512 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000014568.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.420.10 UniProtKB/TrEMBL
  3.40.50.2300 UniProtKB/TrEMBL
  paz domain UniProtKB/TrEMBL
InterPro ArgoL1 UniProtKB/TrEMBL
  PAZ_dom UniProtKB/TrEMBL
  PAZ_dom_sf UniProtKB/TrEMBL
  Piwi UniProtKB/TrEMBL
  RNaseH-like_sf UniProtKB/TrEMBL
  RNaseH_sf UniProtKB/TrEMBL
KEGG Report csab:103215451 UniProtKB/TrEMBL
NCBI Gene PIWIL2 ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 2C UniProtKB/TrEMBL
  PIWI-LIKE PROTEIN 2 UniProtKB/TrEMBL
Pfam ArgoL1 UniProtKB/TrEMBL
  PAZ UniProtKB/TrEMBL
  Piwi UniProtKB/TrEMBL
PROSITE PAZ UniProtKB/TrEMBL
  PIWI UniProtKB/TrEMBL
SMART DUF1785 UniProtKB/TrEMBL
  PAZ UniProtKB/TrEMBL
  Piwi UniProtKB/TrEMBL
Superfamily-SCOP SSF101690 UniProtKB/TrEMBL
  SSF53098 UniProtKB/TrEMBL
UniProt A0A0D9RV98 ENTREZGENE, UniProtKB/TrEMBL