PIWIL2 (piwi like RNA-mediated gene silencing 2)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Gene: PIWIL2 (piwi like RNA-mediated gene silencing 2) Sus scrofa

Analyze

Symbol:

PIWIL2

Name:

piwi like RNA-mediated gene silencing 2 (Ensembl:piwi like RNA-mediated silencing 2)

RGD ID:

13893804

Description:

ENCODES a protein that exhibits mRNA binding (inferred); piRNA binding (inferred); RNA binding (inferred); INVOLVED IN piRNA-mediated retrotransposon silencing by heterochromatin formation (ortholog); positive regulation of cytoplasmic translation (ortholog); positive regulation of meiosis I (ortholog); ASSOCIATED WITH celiac disease (ortholog); Conotruncal Cardiac Defects (ortholog); FOUND IN chromatoid body (inferred); cytoplasm (inferred); dense body (inferred)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

piwi-like 2; piwi-like protein 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	6,560,565 - 6,632,523 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	6,560,402 - 6,632,524 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	6,994,765 - 7,064,683 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

celiac disease (ISO)

Conotruncal Cardiac Defects (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell differentiation (IEA)

germ-line stem cell population maintenance (IEA)

meiotic cell cycle (IEA)

negative regulation of circadian rhythm (IEA)

oogenesis (IEA)

piRNA processing (IEA)

piRNA-mediated retrotransposon silencing by heterochromatin formation (IEA,ISO)

positive regulation of cytoplasmic translation (ISO)

positive regulation of meiosis I (IEA,ISO)

positive regulation of translation (IEA)

regulation of translation (IEA)

regulatory ncRNA-mediated gene silencing (IEA)

retrotransposon silencing by heterochromatin formation (IEA,ISO)

retrotransposon silencing by mRNA destabilization (IEA)

secondary piRNA processing (IEA)

siRNA-mediated retrotransposon silencing by heterochromatin formation (IEA)

spermatogenesis (IEA)

Cellular Component

chromatoid body (IEA)

cytoplasm (IEA)

dense body (IEA)

nucleus (IBA,IEA)

P granule (IBA,IEA)

perinucleolar chromocenter (IEA)

PET complex (IEA)

pi-body (IEA)

Molecular Function

mRNA binding (IEA)

piRNA binding (IBA,IEA)

protein binding (ISO)

RNA binding (IEA)

RNA endonuclease activity (IBA,IEA)

References

Additional References at PubMed

PMID:20454920	PMID:22301074	PMID:22952772	PMID:30032202

Genomics

Comparative Map Data

PIWIL2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	6,560,565 - 6,632,523 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	6,560,402 - 6,632,524 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	6,994,765 - 7,064,683 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PIWIL2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	22,275,316 - 22,357,568 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	22,275,316 - 22,357,568 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	22,132,829 - 22,215,081 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	22,188,796 - 22,269,545 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	22,188,800 - 22,269,529	NCBI
Celera	8	21,095,224 - 21,174,910 (+)	NCBI		Celera
Cytogenetic Map	8	p21.3	NCBI
HuRef	8	20,675,010 - 20,755,706 (+)	NCBI		HuRef
CHM1_1	8	22,334,485 - 22,415,561 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	22,549,271 - 22,631,533 (+)	NCBI		T2T-CHM13v2.0

Piwil2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	70,609,926 - 70,674,338 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	70,609,926 - 70,666,832 (-)	Ensembl		GRCm39 Ensembl
GRCm38	14	70,372,477 - 70,436,898 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	70,372,477 - 70,429,383 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	70,772,287 - 70,828,901 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	69,107,560 - 69,164,174 (-)	NCBI		MGSCv36	mm8
Celera	14	67,913,743 - 67,970,583 (-)	NCBI		Celera
Cytogenetic Map	14	D2	NCBI
cM Map	14	36.32	NCBI

Piwil2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	51,841,104 - 51,907,729 (-)	NCBI		GRCr8
mRatBN7.2	15	45,431,402 - 45,498,034 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	45,431,703 - 45,497,702 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	49,549,570 - 49,615,564 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	50,661,059 - 50,727,061 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	47,520,373 - 47,586,368 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	52,037,693 - 52,116,277 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	52,037,693 - 52,116,001 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	55,760,496 - 55,839,763 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	50,757,820 - 50,823,943 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	50,775,399 - 50,839,987 (-)	NCBI
Celera	15	45,111,291 - 45,176,770 (-)	NCBI		Celera
Cytogenetic Map	15	p11	NCBI

Piwil2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	45,737,674 - 45,819,873 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	45,737,674 - 45,819,478 (+)	NCBI	ChiLan1.0	ChiLan1.0

PIWIL2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	40,777,023 - 40,865,972 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	16,502,223 - 16,591,180 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	21,520,166 - 21,608,374 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	18,459,052 - 18,546,688 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	18,463,173 - 18,544,186 (+)	Ensembl	panpan1.1		panPan2

PIWIL2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	34,911,120 - 34,987,287 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	34,912,358 - 34,987,339 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	35,501,009 - 35,577,016 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	35,122,157 - 35,198,747 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	35,123,395 - 35,198,755 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	35,068,198 - 35,144,239 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	34,922,162 - 34,998,398 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	35,077,336 - 35,153,884 (-)	NCBI		UU_Cfam_GSD_1.0

Piwil2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	12,435,718 - 12,493,669 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936555	6,078,681 - 6,133,020 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936555	6,078,681 - 6,133,184 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PIWIL2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	20,347,998 - 20,436,016 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	20,352,771 - 20,433,947 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	21,799,635 - 21,889,513 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Piwil2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624758	17,834,191 - 17,902,575 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624758	17,834,268 - 17,911,886 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in PIWIL2
1838 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001194971	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005657209	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000096	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CT827951	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU468634	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01024528	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GQ329719	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JX036537	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000027223 ⟹ ENSSSCP00000022355

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	14	6,560,565 - 6,632,523 (+)	Ensembl

RefSeq Acc Id:

NM_001194971 ⟹ NP_001181900

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	14	6,563,668 - 6,630,203 (+)	NCBI

Sequence:

show sequence

ATGGATCCTGTTCGACCACCCTCCAGGGTCCTGTCTCCTGTGCACCCATCTCGCTCTGTGCGGA
TGCCAGGCTCTCGGCCACAAGCTTCAAAACCTTTGGACTCAGCTCTGGGTAGGGCAGGACCTTC
AGGCAGAGGCCATGTATTTGGAATGGGAGAAGAGCCAAGCCCACAGAGTGGGCCAACACAAAGG
GAATCTGTGGGTTTGGTCCCCATGTTCCAAGGACTGGGCCTTGAAACAGCATCCCAGACCTCTC
TGAAACAGGAAATGCCTCCTTTAGGTAGAGGCATTTTAGGTCGAGGCTTGTCTACCAGGGTGGC
ACGCAAGGACAAAGAAGAACCCCATCCCACTCTTCTGGATCCTTCAGTGTTGGCAGCTGGGGAT
AGCAAGATGGCAGAGGCCTCTTTTGGTTGGAATAGAATGCTTGGAAGAGGGAATTTGGATGCAT
CTTTATTACCTGTGGGAAGAGCAGGTCGTGGTATTGGCAGAGGAGTATACAAGCCTCTGAGTGC
TCCCAGCCTGACAGGTGTTATTGGTAGAGGAGTGTACAAGGCTCCAGGCCTGACTTCTCCGGAT
CCCGCCCAGCTGTCATCTCCGTCACCCCTGCCTCCAGCACCACTGCACTCTCTGGATCACCCTC
CACTTGGGACTGCAGAACACAAGGAAAAAGAGATTCTTGTGAAGCAAGGATCAAAAGGAACACC
TCAATATTTGGGATTAAACCTTATCAAAATACAGTGTCAAAATGAAGCAGTTTATCAATATCAT
GTGACTTTCAGCCCCAATGTGGAGTGCAAAAGAATGAGGTTTGGCATGTTGAGGGACCATCAAG
CTGTCACCGGAAACACCACTGCTTTTGATGGATCCATTCTTTATCTGCCTGTTAAGCTTCAACA
AGTTCTTGAGTTAAAAAGTCAAAGGAAAACTGACAGTGCCGAGATCACCATTAAGATTCAGTTG
ACAAAGATCCTGGAGCCCTGTTCTGACTTGTGCATTCCCTTCTACAATGTTGTTTTCCGTCGGG
TAATGAAACTTCTAGATATGACACTTGTGGGGAGAAACTTCTATGACCCTATACGTGTTATGGT
ACTACAGCAACACAGATTGCAGATCTGGCCAGGCTATGCAGCTAGCATCCGAAGGACAGATGGA
GGCCTTTTCCTGCTAGCCGATGTCTCCCACAAGGTCATTCGGAATGATTCTGTGCTGGACATCA
TGCATGCCATGTACCAACAGAACAAAGAAAACTTCAAGGATGAGTGCACTAAGCTTCTGGTTGG
CAGTATTGTTATAACCCGATATAGTAATCGTACCTATCGTATTGATGATGTGGATTGGAACAAG
ACTCCAAAAGACAGCTTCACCATGTCTGATGGGAAGGAGATTACCTTCTTGGAATACTACAGCA
AAAACTATGGGATCACAGTAAGGGAAGAGGACCAGCCACTGCTCATCCACAGGCCCAGTGAGCG
ACAGAATAACCAGGGGATGCTGCTAAAAGGTGAAATCCTGCTGCTGCCTGAGCTTTCCTTCATG
ACTGGAATCCCTGAGAAGATGAAGAAGGACTTTAGAGCCATGAAGGATTTGACCCAGCAGATCA
ACCTGAGCCCCAAGCAGCACCATGATGCTCTGGAATGCTTGCTACAGAGAATTTCAAAAAATGA
GATAGCCAACAATGAACTGACACGTTGGGGACTCTGCCTGCAGAAGGATGTACATAAGGTTGAA
GGACGTGTTCTGCCAATGGAAAGAATTAACCTAAGAAGTACATCATTTATCCCATCTCAGGAGC
TAAACTGGATGAAGGAAATAACCAGAGATCTTTCCATCTTGACTGTCCCCATGCATTTCTGGGC
GCTCTTTTACCCAAAGAGAGCAGTGGATCAGGCCCGAGAACTGGTGAACATGTTAGAGAAGGTA
GCTGGTCCCATGGGCATGCGCATGAGCCCGCCGGCCTGTGTGGAGCTGAAGGATGATCGCATAG
AGACCTACGTCAGAACCATTCAGTCCATCCTGGGAGTTGAGGGGAAGATACAGATGGTTGTTTG
CATAATCATGGGCACACGTGATGATCTCTATGGGGCCATTAAAAAGCTGTGCTGTGTGCAGACT
CCTGTGCCCTCGCAGGTCATCAATGTCCGAACCATTAGTCAGCCCACCAAGCTTCGGAGTGTGG
CGCAGAAAATTTTACTTCAGATTAACTGTAAATTGGGTGGTGAACTCTGGGGAGTGGATATTCC
TCTGAAACAATTAATGGTGATTGGGATAGATGTTTACCATGACCCCAGCAGAGGCATGCGCTCA
GTGGTTGGCTTTGTTGCGAGCATCAATCTCACTCTCACAAAGTGGCATTCACAAGTGGTATTCC
AGATGCCTCATCAGGAGATTGTGGATAGCCTGAAGTTGTGCCTGGTGGGCTCCTTAAAAAAGTT
TTATCAGGTGAACCACTGTCTCCCAGAGAAGATTGTGGTGTACCGTGACGGAGTGTCTGATGGC
CAACTAAAGACAGTAGCCGGCTTTGAGATTCCTCAGCTCCAGCAGTGTTTTGAAGCTTTTCAGA
ATTATCAGCCCAAGATGGTGGTATTTGTAGTTCAGAAGAAGATCAGCACCAATCTGTACCTGGC
TGCTGCCCAGCACTTTGTGACTCCCTCCCCTGGGACTGTGGTAGATCATACAATAACAAGCTGT
GAGTGGGTGGACTTCTACCTTCTTGCCCATCATGTACGGCAGGGGTGTGGCATTCCTACCCATT
ATGTTTGCGTTCTCAACACTGCAAACCTGAGCCCTGATCATATGCAGAGGTTGACTTTCAAACT
GTGCCACATGTACTGGAATTGGCCTGGTACCATCAGAGTTCCAGCTCCTTGCAAGTACGCCCAC
AAACTGGCCTTCCTGTCAGGACAAATCTTGCATCGTGAACCAGCCATCCAGCTGTGTGAGAACC
TGTTCTTTCTGTGA

hide sequence

RefSeq Acc Id:

XM_005657209 ⟹ XP_005657266

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	14	6,560,402 - 6,632,524 (+)	NCBI

Sequence:

show sequence

TCCTGGTTGGTTTGGGCTCATTAGTACTGAGGCATGATGGGGAGTCCAGAATGTAACGGATTTT
AACGATTTTAACGCTTTTTACTTCCGGGCTCCAACTATCAGCACCCCTTTGTAGGGAACGTCGA
GGATGAATCCGCTAGAGAGGGAGAAGGAGGTGCTCTGTGCAGAAGAGCCAATGAGACGGCTGAC
TCTTGTGAGTGACATATCGTTTGGCCAATGGGTTTACTCCCTGAGGCCCCGCGAGAGGACCGGA
ACTTGGGAGTCTGAGTCTGTGGGCGCGTGGTGTGGTGCGACCCTTGAGCGCAGCGTTTTCTTGA
GCCCTCCGCGGAGCTGCGCGAGCTTTGGAGTGCTGCCTTTCAATGGATCCTGTTCGACCACCCT
CCAGGGTCCTGTCTCCTGTGCACCCATCTCGCTCTGTGCGGATGCCAGGCTCTCGGCCACAAGC
TTCAAAACCTTTGGACTCAGCTCTGGGTAGGGCAGGACCTTCAGGCAGAGGCCATGTATTTGGA
ATGGGAGAAGAGCCAAGCCCACAGAGTGGGCCAACACAAAGGGAATCTGTGGGTTTGGTCCCCA
TGTTCCAAGGACTGGGCCTTGAAACAGCATCCCAGACCTCTCTGAAACAGGAAATGCCTCCTTT
AGGTAGAGGCATTTTAGGTCGAGGCTTGTCTACCAGGGTGGCACGCAAGGACAAAGAAGAACCC
CATCCCACTCTTCTGGATCCTTCAGTGTTGGCAGCTGGGGATAGCAAGATGGCAGAGGCCTCTT
TTGGTTGGAATAGAATGCTTGGAAGAGGGAATTTGGATGCATCTTTATTACCTGTGGGAAGAGC
AGGTCGTGGTATTGGCAGAGGAGTATACAAGCCTCTGAGTGCTGCCAGCCTGACAGGTGTTATT
GGTAGAGGAGTGTACAAGGCTCCAGGCCTGACTTCTCCGGATCCCGCCCAGCTGTCATCTCCGT
CACCCCTGCCTCCAGCACCACTGCACTCTCTGGATCACCCTCCACTTGGGACTGCAGAACACAA
GGAAAAAGAGATTCTTGTGAAGCAAGGATCAAAAGGAACACCTCAATATTTGGGATTAAACCTT
ATCAAAATACAGTGTCAAAATGAAGCAGTTTATCAATATCATGTGACTTTCAGCCCCAATGTGG
AGTGCAAAAGAATGAGGTTTGGCATGTTGAGGGACCATCAAGCTGTCACCGGAAACACCACTGC
TTTTGATGGATCCATTCTTTATCTGCCTGTTAAGCTTCAACAAGTTCTTGAGTTAAAAAGTCAA
AGGAAAACTGACAGTGCCGAGATCACCATTAAGATTCAGTTGACAAAGATCCTGGAGCCCTGTT
CTGACTTGTGCATTCCCTTCTACAATGTTGTTTTCCGTCGGGTAATGAAACTTCTAGATATGAC
ACTTGTGGGGAGAAACTTCTATGACCCTATACGTGTTATGGTACTACAGCAACACAGATTGCAG
ATCTGGCCAGGCTATGCAGCTAGCATCCGAAGGACAGATGGAGGCCTTTTCCTGCTAGCCGATG
TCTCCCACAAGGTCATTCGGAATGATTCTGTGCTGGACATCATGCATGCCATGTACCAACAGAA
CAAAGAAAACTTCAAGGATGAGTGCACTAAGCTTCTGGTTGGCAGTATTGTTATAACCCGATAT
AATAATCGTACCTATCGTATTGATGATGTGGATTGGAACAAGACTCCAAAAGACAGCTTCACCA
TGTCTGATGGGAAGGAGATTACCTTCTTGGAATACTACAGCAAAAACTATGGGATCACAGTAAG
GGAAGAGGACCAGCCACTGCTCATCCACAGGCCCAGTGAGCGACAGAATAACCAGGGGATGCTG
CTAAAAGGTGAAATCCTGCTGCTGCCTGAGCTTTCCTTCATGACTGGAATCCCTGAGAAGATGA
AGAAGGACTTTAGAGCCATGAAGGATTTGACCCAGCAGATCAACCTGAGCCCCAAGCAGCACCA
TGATGCTCTGGAATGCTTGCTACAGAGAATTTCAAAAAATGAGATAGCCAACAATGAACTGACA
CGTTGGGGACTCTGCCTGCAGAAGGATGTACATAAGGTTGAAGGACGTGTTCTGCCAATGGAAA
GAATTAACCTAAGAAGTACATCATTTATCCCATCTCAGGAGCTAAACTGGATGAAGGAAATAAC
CAGAGATCTTTCCATCTTGACTGTCCCCATGCATTTCTGGGCGCTCTTTTACCCAAAGAGAGCA
GTGGATCAGGCCCGAGAACTGGTGAACATGTTAGAGAAGGTAGCTGGTCCCATGGGCATGCGCA
TGAGCCCGCCGGCCTGTGTGGAGCTGAAGGATGATCGCATAGAGACCTACGTCAGAACCATTCA
GTCCATCCTGGGAGTTGAGGGGAAGATACAGATGGTTGTTTGCATAATCATGGGCACACGTGAT
GATCTCTATGGGGCCATTAAAAAGCTGTGCTGTGTGCAGACTCCTGTGCCCTCGCAGGTCATCA
ATGTCCGAACCATTAGTCAGCCCACCAAGCTTCGGAGTGTGGCGCAGAAAATTTTACTTCAGAT
TAACTGTAAATTGGGTGGTGAACTCTGGGGAGTGGATATTCCTCTGAAACAATTAATGGTGATT
GGGATAGATGTTTACCATGACCCCAGCAGAGGCATGCGCTCAGTGGTTGGCTTTGTTGCGAGCA
TCAATCTCACTCTCACAAAGTGGCATTCACAAGTGGTATTCCAGATGCCTCATCAGGAGATTGT
GGATAGCCTGAAGTTGTGCCTGGTGGGCTCCTTAAAAAAGTTTTATCAGGTGAACCACTGTCTC
CCAGAGAAGATTGTGGTGTACCGTGACGGAGTGTCTGATGGCCAACTAAAGACAGTAGCCGGCT
TTGAGATTCCTCAGCTCCAGCAGTGTTTTGAAGCTTTTCAGAATTATCAGCCCAAGATGGTGGT
ATTTGTAGTTCAGAAGAAGATCAGCACCAATCTGTACCTGGCTGCTGCCCAGCACTTTGTGACT
CCCTCCCCTGGGACTGTGGTAGATCATACAATAACAAGCTGTGAGTGGGTGGACTTCTACCTTC
TTGCCCATCATGTACGGCAGGGGTGTGGCATTCCTACCCATTATGTTTGCGTTCTCAACACTGC
AAACCTGAGCCCTGATCATATGCAGAGGTTGACTTTCAAACTGTGCCACATGTACTGGAATTGG
CCTGGTACCATCAGAGTTCCAGCTCCTTGCAAGTACGCCCACAAACTGGCCTTCCTGTCAGGAC
AAATCTTGCATCGTGAACCAGCCATCCAGCTGTGTGAGAACCTGTTCTTTCTGTGACTGGACAG
TCAGTACATGGGCTGGTCAGAGCAGTCAGACTTCTGAACTCAGCTGTGTAGGATCAACAGCGAC
CGAAAGGGGTTTTGTATTGGTGATTTCCCTTTTACCAACACAGTAGAATAAGATACCTTTTTCT
TTTTCTTTCTCTTTTAAACCTGATATCACCAAGAAGCAAGTTCCATTCTAAGTATCAGCTAGAA
ATCTTCCTGTTACCTTTGTAGAGCAAATGGGGATAGTGCTCCAACTGCATAGATGGGGTGGGTG
AAGATGGGACCATTTAAGAGCCTCCAAAGCCAACATGAGCTATAGAAACCTGCAGAAGCAGCAA
TTACACCTATTAAACTCTGCTTACTAAGCCGTTCCCATTTCTGGTGCCAAAGGTGGTGATGAAT
GAAGTCACTGCAAGTATCTTAAAGTACAGAGCTACTTTATTTAGGCAACTGGGAAAGGTAATAA
AAAGGCAAAGTTTAAGATACAGCTCTCGCTGGCAAGTGTGTAAGGCATGTCGTAAAACCACCTG
GTGGGGAGTCAGTGCCTCACTGACTTCATCTTCTCTAGGGATAGAACTGATGATACCTATGACT
TGAGCTAGCTTTGAAAGAGGATGTTTAGCTATTCCTTGGCCTCTTGAGAGAGGCCAGATGCAGT
TTTTTCTGCATATTTCAGTTGCTTTATAGTATGTCTTGTTTTGTTCTGTTTTGGCTATGCCCAT
GGTATGTGCAAGTTCCCATAGCCATGGCAGTGGCAATGCTGGATCCTTAACCCACTGAGCCACC
AGGGAACTCCTATAGTATGCCATGTTGATTTTTTTCCTACCTCCACAGCCCCTATCCCTGCCAG
GCACATACACACACATAGCTTTGCTCCTTGTTACTGATCTTTAGTAAGTTTCATTTTTTTTAAA
TTAAGAATCAGAGGAGTTCCCGTCGTGGCTCAGTGGTTAATGAATCTGACTAGGAACCATGAGG
TTGCAGGTTCGATCCCTGGCCTTGCTCAGTGGGTCAAGGATCTGGCACTGCCATGAGTTGTGGT
GTAGGTCGCATTTGCGGCTCAGATCCCGCTTTGCTGCGTCTCTGGCGTAGGCTGGCGGCTGCAG
CTCCGATTCAACCCAAGCCTGGGAACCTCCATATGCTGCAGGAGCGGCCCTAGAAAAGGCAAAA
AGACACACACACACACACACACACACACACACACACACACACACAAATTAAGAATCAGAACATG
TGAAATTCAACAGCTAGGAAAGTTCATGATGGGGTGTGAGCTATTCCTGACCCCTTCTTCCCAG
TGTGTCACTTTTTCTGTTGATATGTTTCCAAATAGAATCACTCATTTCCCTTGCTCAATATTCT
CTTCCCAGCTGTTGGCTCTTTTTATTATAATTTTTCTGGGAGTTCTTGTGGTACAGCAGAAACG
AATCCGACTAGTAACCATGAGGGTGCGGGTTTGATCCTGGGCCTTGCTCAGTGGGTTAAGGATC
TGGTGTTGCTGTGAGCTGTAGTGTAGATCAAAAGACGAGGCTCAGATCCATCATTGCTGTGGCT
GTGGTGTAGGCCGGCAGCTGTAGCTCTGATTCAACCCCTAGCCTGGGAACTTCCGTATACCTCG
GGTGCGGCCCTGAAAAAAGAGAAAAAAAAAAAAAGAAAATTTTATGAATACACATTAAGGTTTC
CAGAAGTTGGCTTTGGAAAATATGACACACATGCTAAAGACCAGACATTTCAATTTAGAAAGTT
GTCACTATGCCTGTGGATTTCAGTACTTTGGGGAAGAACTATTTTTTTGTGTGTTTATTTTTCC
CCATTTTAAAATCTTCCAGTCCCTTCAGGGCTAATTCAGTCTTATCGTGCTTTACCCAAGTTTT
AAAAACCAGTTTTATTTAACCTTTTCAAATTTGTATTTATTTTTTGGTGTGATAGCAGGGAGGG
AATGAGGCAGAAATCCCCATTTTATATGACAGTATGTGAGAAGAGAAACTTTAGCTAAAAACTC
CTTTTAAGAAGGAAGCAGAGTTAGCATAGTGCACTCCCGAAGCCACTCACAGTGCGGGACGGGG
AAGGCTGAGACCTGGGATTTCAACACCGCATCAGATCACTGGGGTTTAGCTTAAGAGTTTTCTG
GTTTTCTTTGGAAGTGTTTTGAATTTCTCCTTTGAAGTTAGATTTCCTAATACTCGTTTTCTGT
TATATTAATTAGAAAAGACAAATACTTGAATATAATATAAACATTTCTTCTCTTTTATTCCTAG
TTTTCTTGGCTTGTTTTTTCAGTCTTAACGTGAAATGACTGGGTCATGGGGTAGGAAATAAAAC
AAATTTGTA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001181900	(Get FASTA)	NCBI Sequence Viewer
	XP_005657266	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ADH59740	(Get FASTA)	NCBI Sequence Viewer
	AFO70085	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000022355
	ENSSSCP00000022355.1
	ENSSSCP00015029918.1
	ENSSSCP00015029976.1
	ENSSSCP00030027122.1
	ENSSSCP00035046801.1
	ENSSSCP00040016999.1
	ENSSSCP00045017188.1
	ENSSSCP00050046077.1
	ENSSSCP00055035987.1
	ENSSSCP00060000159.1
	ENSSSCP00065003027.1
	ENSSSCP00070040696.1

RefSeq Acc Id:	XP_005657266 ⟸ XM_005657209
- Peptide Label:	isoform X1
- UniProtKB:	I3LE69 (UniProtKB/TrEMBL), A0A4X1VIP5 (UniProtKB/TrEMBL), I7DLY7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDPVRPPSRVLSPVHPSRSVRMPGSRPQASKPLDSALGRAGPSGRGHVFGMGEEPSPQSGPTQR ESVGLVPMFQGLGLETASQTSLKQEMPPLGRGILGRGLSTRVARKDKEEPHPTLLDPSVLAAGD SKMAEASFGWNRMLGRGNLDASLLPVGRAGRGIGRGVYKPLSAASLTGVIGRGVYKAPGLTSPD PAQLSSPSPLPPAPLHSLDHPPLGTAEHKEKEILVKQGSKGTPQYLGLNLIKIQCQNEAVYQYH VTFSPNVECKRMRFGMLRDHQAVTGNTTAFDGSILYLPVKLQQVLELKSQRKTDSAEITIKIQL TKILEPCSDLCIPFYNVVFRRVMKLLDMTLVGRNFYDPIRVMVLQQHRLQIWPGYAASIRRTDG GLFLLADVSHKVIRNDSVLDIMHAMYQQNKENFKDECTKLLVGSIVITRYNNRTYRIDDVDWNK TPKDSFTMSDGKEITFLEYYSKNYGITVREEDQPLLIHRPSERQNNQGMLLKGEILLLPELSFM TGIPEKMKKDFRAMKDLTQQINLSPKQHHDALECLLQRISKNEIANNELTRWGLCLQKDVHKVE GRVLPMERINLRSTSFIPSQELNWMKEITRDLSILTVPMHFWALFYPKRAVDQARELVNMLEKV AGPMGMRMSPPACVELKDDRIETYVRTIQSILGVEGKIQMVVCIIMGTRDDLYGAIKKLCCVQT PVPSQVINVRTISQPTKLRSVAQKILLQINCKLGGELWGVDIPLKQLMVIGIDVYHDPSRGMRS VVGFVASINLTLTKWHSQVVFQMPHQEIVDSLKLCLVGSLKKFYQVNHCLPEKIVVYRDGVSDG QLKTVAGFEIPQLQQCFEAFQNYQPKMVVFVVQKKISTNLYLAAAQHFVTPSPGTVVDHTITSC EWVDFYLLAHHVRQGCGIPTHYVCVLNTANLSPDHMQRLTFKLCHMYWNWPGTIRVPAPCKYAH KLAFLSGQILHREPAIQLCENLFFL hide sequence

RefSeq Acc Id:

NP_001181900 ⟸ NM_001194971

- UniProtKB:

D9YJ49 (UniProtKB/TrEMBL), A0A4X1VIP5 (UniProtKB/TrEMBL), I7DLY7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDPVRPPSRVLSPVHPSRSVRMPGSRPQASKPLDSALGRAGPSGRGHVFGMGEEPSPQSGPTQR
ESVGLVPMFQGLGLETASQTSLKQEMPPLGRGILGRGLSTRVARKDKEEPHPTLLDPSVLAAGD
SKMAEASFGWNRMLGRGNLDASLLPVGRAGRGIGRGVYKPLSAPSLTGVIGRGVYKAPGLTSPD
PAQLSSPSPLPPAPLHSLDHPPLGTAEHKEKEILVKQGSKGTPQYLGLNLIKIQCQNEAVYQYH
VTFSPNVECKRMRFGMLRDHQAVTGNTTAFDGSILYLPVKLQQVLELKSQRKTDSAEITIKIQL
TKILEPCSDLCIPFYNVVFRRVMKLLDMTLVGRNFYDPIRVMVLQQHRLQIWPGYAASIRRTDG
GLFLLADVSHKVIRNDSVLDIMHAMYQQNKENFKDECTKLLVGSIVITRYSNRTYRIDDVDWNK
TPKDSFTMSDGKEITFLEYYSKNYGITVREEDQPLLIHRPSERQNNQGMLLKGEILLLPELSFM
TGIPEKMKKDFRAMKDLTQQINLSPKQHHDALECLLQRISKNEIANNELTRWGLCLQKDVHKVE
GRVLPMERINLRSTSFIPSQELNWMKEITRDLSILTVPMHFWALFYPKRAVDQARELVNMLEKV
AGPMGMRMSPPACVELKDDRIETYVRTIQSILGVEGKIQMVVCIIMGTRDDLYGAIKKLCCVQT
PVPSQVINVRTISQPTKLRSVAQKILLQINCKLGGELWGVDIPLKQLMVIGIDVYHDPSRGMRS
VVGFVASINLTLTKWHSQVVFQMPHQEIVDSLKLCLVGSLKKFYQVNHCLPEKIVVYRDGVSDG
QLKTVAGFEIPQLQQCFEAFQNYQPKMVVFVVQKKISTNLYLAAAQHFVTPSPGTVVDHTITSC
EWVDFYLLAHHVRQGCGIPTHYVCVLNTANLSPDHMQRLTFKLCHMYWNWPGTIRVPAPCKYAH
KLAFLSGQILHREPAIQLCENLFFL

hide sequence

RefSeq Acc Id:

ENSSSCP00000022355 ⟸ ENSSSCT00000027223

Protein Domains

PAZ Piwi

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000030228	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00015052500	UniProtKB/TrEMBL
	ENSSSCG00030042431	UniProtKB/TrEMBL
	ENSSSCG00035078545	UniProtKB/TrEMBL
	ENSSSCG00040029700	UniProtKB/TrEMBL
	ENSSSCG00045014524	UniProtKB/TrEMBL
	ENSSSCG00050076311	UniProtKB/TrEMBL
	ENSSSCG00055022820	UniProtKB/TrEMBL
	ENSSSCG00060000606	UniProtKB/TrEMBL
	ENSSSCG00065004976	UniProtKB/TrEMBL
	ENSSSCG00070024117	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000027223	ENTREZGENE
	ENSSSCT00000027223.4	UniProtKB/TrEMBL
	ENSSSCT00015074584.1	UniProtKB/TrEMBL
	ENSSSCT00015074743.1	UniProtKB/TrEMBL
	ENSSSCT00030059303.1	UniProtKB/TrEMBL
	ENSSSCT00035108105.1	UniProtKB/TrEMBL
	ENSSSCT00040040553.1	UniProtKB/TrEMBL
	ENSSSCT00045024880.1	UniProtKB/TrEMBL
	ENSSSCT00050104908.1	UniProtKB/TrEMBL
	ENSSSCT00055045164.1	UniProtKB/TrEMBL
	ENSSSCT00060000737.1	UniProtKB/TrEMBL
	ENSSSCT00065006970.1	UniProtKB/TrEMBL
	ENSSSCT00070048204.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.420.10	UniProtKB/TrEMBL
	3.40.50.2300	UniProtKB/TrEMBL
	paz domain	UniProtKB/TrEMBL
InterPro	ArgoL1	UniProtKB/TrEMBL
	PAZ_dom	UniProtKB/TrEMBL
	PAZ_dom_sf	UniProtKB/TrEMBL
	Piwi	UniProtKB/TrEMBL
	RNaseH-like_sf	UniProtKB/TrEMBL
	RNaseH_sf	UniProtKB/TrEMBL
KEGG Report	ssc:100152834	UniProtKB/TrEMBL
NCBI Gene	PIWIL2	ENTREZGENE
PANTHER	EUKARYOTIC TRANSLATION INITIATION FACTOR 2C	UniProtKB/TrEMBL
	PIWI-LIKE PROTEIN 2	UniProtKB/TrEMBL
Pfam	ArgoL1	UniProtKB/TrEMBL
	PAZ	UniProtKB/TrEMBL
	Piwi	UniProtKB/TrEMBL
PROSITE	PAZ	UniProtKB/TrEMBL
	PIWI	UniProtKB/TrEMBL
SMART	DUF1785	UniProtKB/TrEMBL
	PAZ	UniProtKB/TrEMBL
	Piwi	UniProtKB/TrEMBL
Superfamily-SCOP	SSF101690	UniProtKB/TrEMBL
	SSF53098	UniProtKB/TrEMBL
UniProt	A0A4X1VIP5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1BC86_PIG	UniProtKB/TrEMBL
	A0A8D1U900_PIG	UniProtKB/TrEMBL
	D9YJ49	ENTREZGENE, UniProtKB/TrEMBL
	I3LE69	ENTREZGENE, UniProtKB/TrEMBL
	I7DLY7	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:98198	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

alimentary part of gastrointestinal system

circulatory system

endocrine system

hemolymphoid system

nervous system

reproductive system

Below cutoff