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ONTOLOGY REPORT - ANNOTATIONS

Term:chondrocyte development
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Accession:GO:0002063 term browser browse the term
Definition:The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.


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chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856465 (PMID:9664687)		 Ensembl
RGD		 PMID:9664687 GO_REF:0000107 NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (PMID:9442116) RGD PMID:9442116 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Bpnt2 3'(2'), 5'-bisphosphate nucleotidase 2 acts_upstream_of_or_within ISO MGI:3806990 (PMID:18539921) RGD PMID:18539921 NCBI chr 5:17,775,684...17,802,570
Ensembl chr 5:17,772,608...17,802,570 		JBrowse link
G Chst11 carbohydrate sulfotransferase 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3768254 (PMID:16079159)		 Ensembl
RGD		 PMID:16079159 GO_REF:0000107 NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111 		JBrowse link
G Chsy1 chondroitin sulfate synthase 1 acts_upstream_of_or_within ISO MGI:5007063 (PMID:22280990) RGD PMID:22280990 NCBI chr 1:119,689,626...119,750,711
Ensembl chr 1:119,686,350...119,750,601 		JBrowse link
G Col11a1 collagen type XI alpha 1 chain acts_upstream_of_or_within ISO MGI:1856399 (PMID:4100752) RGD PMID:4100752 NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853 		JBrowse link
G Comp cartilage oligomeric matrix protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3758741|MGI:5550566 (PMID:17588960), (PMID:22006726)		 Ensembl
RGD		 PMID:17588960 PMID:22006726 GO_REF:0000107 NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845 		JBrowse link
G Ecm1 extracellular matrix protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:20138147)		 Ensembl
RGD		 PMID:20138147 GO_REF:0000107 NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:2183829 (PMID:12865332) RGD PMID:12865332 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Fgf18 fibroblast growth factor 18 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2178751 (PMID:17014841)		 Ensembl
RGD		 PMID:17014841 GO_REF:0000107 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818 		JBrowse link
G Hoxa11 homeobox A11 acts_upstream_of ISO MGI:96203 (PMID:14668414) RGD PMID:14668414 NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:81,342,528...81,346,232 		JBrowse link
G Hoxd11 homeobox D11 acts_upstream_of ISO MGI:96172 (PMID:14668414) RGD PMID:14668414 NCBI chr 3:59,584,840...59,587,257
Ensembl chr 3:59,585,039...59,586,783 		JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 acts_upstream_of_or_within ISO MGI:5007248 (PMID:21606205) RGD PMID:21606205 NCBI chr13:94,970,421...95,012,071
Ensembl chr13:94,970,424...95,011,972 		JBrowse link
G Msx2 msh homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1926381 (PMID:10742104)		 Ensembl
RGD		 PMID:10742104 GO_REF:0000107 NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879 		JBrowse link
G Rarg retinoic acid receptor, gamma involved_in ISO (MGI:3848572|PMID:19389355) RGD PMID:19389355 MGI:3848572 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177 		JBrowse link
G Runx2 RUNX family transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2176466 (PMID:10213384)		 Ensembl
RGD		 PMID:10213384 GO_REF:0000107 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 acts_upstream_of_or_within ISO MGI:3810257 (PMID:18729207) RGD PMID:18729207 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
G Shox2 SHOX homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3605739 (PMID:17481601)		 Ensembl
RGD		 PMID:17481601 GO_REF:0000107 NCBI chr 2:151,217,049...151,227,180
Ensembl chr 2:151,217,552...151,227,143 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 acts_upstream_of_or_within ISO MGI:3575405 (PMID:17591962), (PMID:24505141) RGD PMID:17591962 PMID:24505141 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (PMID:18415932) RGD PMID:18415932 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Sulf1 sulfatase 1 involved_in IEA
ISO
ISS		 GO_REF:0000104
(MGI:5306560|PMID:20479257)
GO_REF:0000024		 UniProt
RGD		 PMID:20479257 GO_REF:0000024 GO_REF:0000104 MGI:5306560 NCBI chr 5:6,362,894...6,526,174
Ensembl chr 5:6,362,911...6,525,584 		JBrowse link
G Sulf2 sulfatase 2 involved_in ISO (MGI:5306560|PMID:20479257) RGD PMID:20479257 MGI:5306560 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415 		JBrowse link
chondrocyte development involved in endochondral bone morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serpinh1 serpin family H member 1 acts_upstream_of_or_within ISO MGI:2176070|MGI:5505265 (PMID:22492985) RGD PMID:22492985 NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856877 (PMID:21788370)		 Ensembl
RGD		 PMID:21788370 GO_REF:0000107 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
chondrocyte hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (PMID:23958822) RGD PMID:23958822 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357 		JBrowse link
G Mex3c mex-3 RNA binding family member C acts_upstream_of_or_within ISO MGI:3764947 (PMID:22357625) RGD PMID:22357625 NCBI chr18:67,167,600...67,188,595
Ensembl chr18:67,166,718...67,188,595 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4950303|PMID:21367821)		 UniProt
RGD		 PMID:21367821 GO_REF:0000024 MGI:4950303 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
growth plate cartilage chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col27a1 collagen type XXVII alpha 1 chain involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:5315593 (PMID:22206015)		 Ensembl
RGD		 PMID:22206015 GO_REF:0000107 NCBI chr 5:76,647,302...76,765,989
Ensembl chr 5:76,647,429...76,765,174 		JBrowse link
G Poc1a POC1 centriolar protein A acts_upstream_of_or_within ISO MGI:2135614 (PMID:26496357) RGD PMID:26496357 NCBI chr 8:106,922,058...106,991,678
Ensembl chr 8:106,922,978...106,991,089 		JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:152,660,259...152,671,682
Ensembl chr 1:152,656,693...152,672,588 		JBrowse link
growth plate cartilage chondrocyte growth term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst5 cystatin D involved_in ISO MGI:3629665 (PMID:16680148) RGD PMID:16680148 NCBI chr 3:137,573,194...137,577,754
Ensembl chr 3:137,573,194...137,577,754 		JBrowse link
G Rarg retinoic acid receptor, gamma involved_in ISO (MGI:3848572|PMID:19389355) RGD PMID:19389355 MGI:3848572 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5317468|PMID:22421045)		 UniProt
RGD		 PMID:22421045 GO_REF:0000024 MGI:5317468 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2384513 (PMID:21420963)		 Ensembl
RGD		 PMID:21420963 GO_REF:0000107 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
growth plate cartilage chondrocyte morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Matn1 matrilin 1 acts_upstream_of_or_within ISO MGI:2153042|MGI:3663272 (PMID:16877353) RGD PMID:16877353 NCBI chr 5:143,117,198...143,127,140
Ensembl chr 5:143,117,504...143,127,059 		JBrowse link
negative regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pthlh parathyroid hormone-like hormone acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:90087)
GO_REF:0000107		 RGD
Ensembl		 PMID:90087 GO_REF:0000107 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847 		JBrowse link
G Rflna refilin A involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1923816 (PMID:24436304)		 GO_Central
RGD		 PMID:24436304 GO_REF:0000033 NCBI chr12:31,633,360...31,642,313
Ensembl chr12:31,633,361...31,642,317 		JBrowse link
G Rflnb refilin B involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1920371 (PMID:24436304)		 GO_Central
RGD		 PMID:24436304 GO_REF:0000033 NCBI chr10:60,893,693...60,899,970
Ensembl chr10:60,893,713...60,899,976 		JBrowse link
positive regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoxa11 homeobox A11 acts_upstream_of_or_within ISO MGI:96203 (PMID:14668414) RGD PMID:14668414 NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:81,342,528...81,346,232 		JBrowse link
G Hoxd11 homeobox D11 acts_upstream_of_or_within ISO MGI:96172 (PMID:14668414) RGD PMID:14668414 NCBI chr 3:59,584,840...59,587,257
Ensembl chr 3:59,585,039...59,586,783 		JBrowse link
positive regulation of chondrocyte hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad7 SMAD family member 7 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6377914|PMID:29503843)		 Ensembl
RGD		 PMID:29503843 GO_REF:0000107 MGI:6377914 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin2 axin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3579503 (PMID:19623616)		 Ensembl
RGD		 PMID:19623616 GO_REF:0000107 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19694
    cellular process 18196
      cellular developmental process 4695
        cell development 3269
          chondrocyte development 36
            chondrocyte development involved in endochondral bone morphogenesis + 10
            chondrocyte hypertrophy + 7
            chondrocyte morphogenesis + 1
            negative regulation of chondrocyte development + 3
            positive regulation of chondrocyte development + 3
            regulation of chondrocyte development + 7
Path 2
Term Annotations click to browse term
  biological_process 19694
    developmental process 6963
      anatomical structure development 6486
        multicellular organism development 5239
          system development 4526
            skeletal system development 575
              cartilage development 236
                chondrocyte differentiation 130
                  chondrocyte development 36
                    chondrocyte development involved in endochondral bone morphogenesis + 10
                    chondrocyte hypertrophy + 7
                    chondrocyte morphogenesis + 1
                    negative regulation of chondrocyte development + 3
                    positive regulation of chondrocyte development + 3
                    regulation of chondrocyte development + 7
paths to the root