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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Pseudomonas Infections
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Accession:DOID:9007417 term browser browse the term
Definition:Infections with bacteria of the genus PSEUDOMONAS.
Synonyms:exact_synonym: Pseudomonas Infection
 narrow_synonym: Pseudomonas aeruginosa CF5 infection
 primary_id: MESH:D011552;   RDO:0002824
 xref: EFO:0001076;   EFO:0001077


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Pseudomonas Infections term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase susceptibility ISO DNA:polymorphism:cds:allele B (human) RGD PMID:22464692 RGD:38455983 NCBI chr 3:10,162,087...10,182,835
Ensembl chr 3:10,162,096...10,191,423 		JBrowse link
G Anxa2 annexin A2 severity ISO RGD PMID:26371245 RGD:38676497 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Ccl17 C-C motif chemokine ligand 17 ISO associated with Cystic Fibrosis RGD PMID:16387607 RGD:4145500 NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 treatment ISO protein:increased expression:lung, secretion (mouse) RGD PMID:20720199 PMID:27175332 RGD:4891951, RGD:32733623 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Cftr CF transmembrane conductance regulator ISO RGD PMID:15039325 PMID:11390493 RGD:36049749, RGD:36049752 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Crp C-reactive protein IEP
ISO		 protein:increased expression:blood
associated with Diabetes Mellitus, Type 1;		 RGD PMID:19561148 PMID:22864910 RGD:5131464, RGD:6906966 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Csf2 colony stimulating factor 2 treatment ISO associated with Neutropenia; RGD PMID:1966550 RGD:10449524 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Dctn4 dynactin subunit 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22772370 NCBI chr18:53,982,355...54,009,409
Ensembl chr18:53,982,358...54,009,399 		JBrowse link
G Defb1 defensin beta 1 no_association
susceptibility		 ISO associated with Cystic Fibrosis;DNA:SNPs:5' utr, intron, 3' utr:multiple (human)
associated with Cystic Fibrosis;DNA:SNPs:5' utr:g.-52G>A, g.-44C>G, g.-20G>A (human)		 RGD PMID:15820309 PMID:20193032 PMID:17960157 RGD:4892256, RGD:4892248, RGD:4892250 NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604 		JBrowse link
G Fcgr2a Fc gamma receptor 2A ISO associated with Cystic Fibrosis; DNA:polymorphism: :p.H131R (human) RGD PMID:15367919 RGD:4144121 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967 		JBrowse link
G Fgf2 fibroblast growth factor 2 treatment ISO human protein in mouse model RGD PMID:26617350 RGD:126928152 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgf7 fibroblast growth factor 7 treatment ISO human protein in rat model RGD PMID:11076810 RGD:126928130 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 susceptibility ISO RGD PMID:22038048 RGD:5687774 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 susceptibility ISO associated with Cystic Fibrosis RGD PMID:18976645 RGD:4142522 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Il13 interleukin 13 ISO associated with Cystic Fibrosis RGD PMID:16387607 RGD:4145500 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il1b interleukin 1 beta treatment ISO associated with Agranulocytosis RGD PMID:7486912 PMID:7923933 RGD:7401204, RGD:10450534 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO associated with Cystic Fibrosis RGD PMID:8327288 RGD:4143202 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il24 interleukin 24 ISO associated with Cystic Fibrosis RGD PMID:19399182 RGD:5147421 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Il27 interleukin 27 ameliorates ISO associated with Sepsis RGD PMID:25074706 RGD:126790541 NCBI chr 1:181,173,108...181,178,720
Ensembl chr 1:181,173,372...181,178,582 		JBrowse link
G Il33 interleukin 33 ISO mRNA:increased expression:lung: RGD PMID:28401938 RGD:40400699 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Il6 interleukin 6 treatment ISO RGD PMID:27175332 RGD:32733623 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 severity ISO associated with Sepsis RGD PMID:16917541 RGD:36049803 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G Klrk1 killer cell lectin like receptor K1 ISO RGD PMID:18832705 RGD:38676496 NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ameliorates ISO associated with Pneumonia, Ventilator-Associated RGD PMID:27506464 RGD:150340682 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mbl2 mannose binding lectin 2 onset ISO associated with Cystic Fibrosis; DNA:polymorphisms:5' utr, exon:multiple (human) RGD PMID:20068595 RGD:4889579 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Pten phosphatase and tensin homolog exacerbates ISO RGD PMID:29246444 RGD:127285608 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptx3 pentraxin 3 susceptibility ISO associated with cystic fibrosis; DNA:SNPs, haplotypes:cds:rs35948036,rs2305619,rs1840680,rs3816527(human) RGD PMID:20927127 RGD:35673347 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323 		JBrowse link
G RT1-Ba RT1 class II, locus Ba ISO associated with Cystic Fibrosis;DNA:polymorphisms, haplotype:cds:HLA-DQA1*0201 (human) RGD PMID:10228112 RGD:5147865 NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744 		JBrowse link
G Sftpb surfactant protein B ameliorates ISO RGD PMID:20007532 RGD:151667448 NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436 		JBrowse link
G Tlr5 toll-like receptor 5 ISO RGD PMID:20566829 RGD:5129679 NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738 		JBrowse link
G Tnf tumor necrosis factor treatment ISO associated with Agranulocytosis RGD PMID:7923933 PMID:8168971 PMID:27175332 RGD:10450534, RGD:10450561, RGD:32733623 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO RGD PMID:20448050 RGD:5131427 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18969
    disease by infectious agent 2216
      Bacterial Infections and Mycoses 1072
        bacterial infectious disease 823
          Gram-Negative Bacterial Infections 200
            Pseudomonas Infections 32
              Flavimonas Oryzihabitans Bacteremia 0
paths to the root