Foxo4 (forkhead box O4) - Rat Genome Database

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Gene: Foxo4 (forkhead box O4) Rattus norvegicus
Analyze
Symbol: Foxo4
Name: forkhead box O4
RGD ID: 1561201
Description: Enables promoter-specific chromatin binding activity. Involved in positive regulation of smooth muscle cell migration; response to nutrient levels; and response to water-immersion restraint stress. Predicted to be located in cytosol. Predicted to be active in nucleus. Biomarker of alcohol-induced mental disorder; gastric ulcer; and paraplegia. Orthologous to human FOXO4 (forkhead box O4); PARTICIPATES IN phosphatidylinositol 3-kinase-Akt signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: forkhead box protein O4; LOC302415; RGD1561201; similar to forkhead protein AFXH
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Foxo4em1Soar
Genetic Models: SD-Foxo4em1Soar
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X70,425,218 - 70,432,120 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX70,425,563 - 70,432,120 (+)EnsemblGRCr8
mRatBN7.2X66,385,241 - 66,392,115 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX66,385,558 - 66,392,115 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX67,868,914 - 67,875,471 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X71,369,302 - 71,375,859 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X68,930,209 - 68,936,766 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X71,155,284 - 71,162,158 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX71,155,601 - 71,162,158 (+)Ensemblrn6Rnor6.0
Rnor_5.0X72,007,762 - 72,014,636 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X89,332,278 - 89,338,835 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX66,741,475 - 66,748,019 (+)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-palmitoylglycerol  (ISO)
3-Nitrobenzanthrone  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-nitrophenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acrylamide  (EXP,ISO)
aflatoxin B1  (EXP)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (EXP,ISO)
antimycin A  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
Azoxymethane  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
choline  (ISO)
cisplatin  (ISO)
clothianidin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cordycepin  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
deguelin  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (ISO)
disulfiram  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
fipronil  (EXP)
folic acid  (ISO)
fonofos  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
Gaillardin  (ISO)
gentamycin  (EXP)
geraniol  (ISO)
L-methionine  (ISO)
LY294002  (ISO)
malathion  (ISO)
naled  (ISO)
nickel atom  (ISO)
niclosamide  (ISO)
NMN zwitterion  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
propiconazole  (ISO)
resveratrol  (EXP,ISO)
rotenone  (ISO)
silicon dioxide  (ISO)
sodium dodecyl sulfate  (ISO)
sunitinib  (ISO)
tamibarotene  (ISO)
terbufos  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
titanium dioxide  (ISO)
toluene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
tungsten  (ISO)
urethane  (ISO)
wortmannin  (ISO)
zinc atom  (ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA,ISO)
cytosol  (IEA,ISO)
nuclear speck  (IEA,ISO)
nucleoplasm  (IEA)
nucleus  (IBA,IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. The role of FoxO4 in the relationship between alcohol-induced intestinal barrier dysfunction and liver injury. Chang B, etal., Int J Mol Med. 2013 Mar;31(3):569-76. doi: 10.3892/ijmm.2013.1229. Epub 2013 Jan 4.
2. Gene and protein expression associated with protein synthesis and breakdown in paraplegic skeletal muscle. Drummond MJ, etal., Muscle Nerve. 2008 Apr;37(4):505-13.
3. Atrogin-1/MAFbx and MuRF1 are downregulated in aging-related loss of skeletal muscle. Edstrom E, etal., J Gerontol A Biol Sci Med Sci. 2006 Jul;61(7):663-74.
4. Effects of aging and caloric restriction on the gene expression of Foxo1, 3, and 4 (FKHR, FKHRL1, and AFX) in the rat skeletal muscles. Furuyama T, etal., Microsc Res Tech. 2002 Nov 15;59(4):331-4.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Effect of the IGF-1/PTEN/Akt/FoxO signaling pathway in the duodenal mucosa of rats subjected to water immersion and restraint stress. Huang P, etal., Genet Mol Res. 2012 Sep 19;11(4):4775-88. doi: 10.4238/2012.September.19.2.
7. Effect of the IGF-1/PTEN/Akt/FoxO signaling pathway on the development and healing of water immersion and restraint stress-induced gastric ulcers in rats. Huang P, etal., Int J Mol Med. 2012 Sep;30(3):650-8. doi: 10.3892/ijmm.2012.1041. Epub 2012 Jun 20.
8. Age-dependent expression of forkhead box O proteins in the duodenum of rats. Huang P, etal., J Zhejiang Univ Sci B. 2011 Sep;12(9):730-5. doi: 10.1631/jzus.B1000298.
9. The AKT1-FOXO4 axis reciprocally regulates hemochorial placentation. Kozai K, etal., Development. 2023 Jan 15;150(2):dev201095. doi: 10.1242/dev.201095. Epub 2023 Jan 17.
10. FoxO4 regulates tumor necrosis factor alpha-directed smooth muscle cell migration by activating matrix metalloproteinase 9 gene transcription. Li H, etal., Mol Cell Biol. 2007 Apr;27(7):2676-86. Epub 2007 Jan 22.
11. Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin. Liu ZP, etal., Dev Cell. 2005 Aug;9(2):261-70.
12. Smad transcription factors. Massagué J, etal., Genes Dev. 2005 Dec 1;19(23):2783-810.
13. Antioxidant administration attenuates mechanical ventilation-induced rat diaphragm muscle atrophy independent of protein kinase B (PKB Akt) signalling. McClung JM, etal., J Physiol. 2007 Nov 15;585(Pt 1):203-15. Epub 2007 Oct 4.
14. FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. Paik JH, etal., Cell. 2007 Jan 26;128(2):309-23. doi: 10.1016/j.cell.2006.12.029.
15. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. How the Smads regulate transcription. Ross S and Hill CS, Int J Biochem Cell Biol. 2008;40(3):383-408. Epub 2007 Oct 7.
Additional References at PubMed
PMID:10217147   PMID:10783894   PMID:11353388   PMID:11689711   PMID:12048180   PMID:12761217   PMID:14966295   PMID:15126506   PMID:15905404   PMID:16272144   PMID:16964248   PMID:19932102  
PMID:22972301   PMID:23332764   PMID:24663349   PMID:25609649   PMID:29409329   PMID:31044535   PMID:33390770   PMID:34251583   PMID:34549304   PMID:35089807  


Genomics

Comparative Map Data
Foxo4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X70,425,218 - 70,432,120 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX70,425,563 - 70,432,120 (+)EnsemblGRCr8
mRatBN7.2X66,385,241 - 66,392,115 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX66,385,558 - 66,392,115 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX67,868,914 - 67,875,471 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X71,369,302 - 71,375,859 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X68,930,209 - 68,936,766 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X71,155,284 - 71,162,158 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX71,155,601 - 71,162,158 (+)Ensemblrn6Rnor6.0
Rnor_5.0X72,007,762 - 72,014,636 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X89,332,278 - 89,338,835 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX66,741,475 - 66,748,019 (+)NCBICelera
Cytogenetic MapXq22NCBI
FOXO4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X71,095,851 - 71,103,532 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX71,095,851 - 71,103,535 (+)Ensemblhg38GRCh38
GRCh37X70,315,701 - 70,323,382 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X70,232,751 - 70,240,109 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34X70,099,230 - 70,106,405NCBI
CeleraX70,670,001 - 70,677,287 (+)NCBICelera
Cytogenetic MapXq13.1NCBI
HuRefX64,135,718 - 64,143,103 (+)NCBIHuRef
CHM1_1X70,208,338 - 70,215,723 (+)NCBICHM1_1
T2T-CHM13v2.0X69,529,947 - 69,537,628 (+)NCBIT2T-CHM13v2.0
Foxo4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X100,297,855 - 100,304,479 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX100,298,134 - 100,304,479 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38X101,254,261 - 101,260,873 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX101,254,528 - 101,260,873 (+)Ensemblmm10GRCm38
MGSCv37X98,449,867 - 98,456,212 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X97,457,247 - 97,462,413 (+)NCBIMGSCv36mm8
CeleraX88,170,853 - 88,177,001 (+)NCBICelera
Cytogenetic MapXDNCBI
cM MapX43.89NCBI
Foxo4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547510,665,987 - 10,674,110 (+)Ensembl
ChiLan1.0NW_00495547510,666,024 - 10,673,717 (+)NCBIChiLan1.0ChiLan1.0
FOXO4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X70,773,607 - 70,781,292 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X70,777,210 - 70,784,897 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X60,364,466 - 60,372,147 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X70,422,504 - 70,429,971 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX70,422,504 - 70,429,971 (+)EnsemblpanPan2panpan1.1
FOXO4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X55,469,738 - 55,477,699 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX55,469,382 - 55,477,699 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX46,296,815 - 46,304,773 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X56,438,647 - 56,446,613 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX56,438,272 - 56,446,607 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X54,406,889 - 54,414,846 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X55,738,314 - 55,746,276 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X55,665,450 - 55,673,416 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Foxo4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X46,731,760 - 46,739,080 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936762493,910 - 501,531 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936762495,271 - 501,278 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FOXO4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX57,132,548 - 57,140,356 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X57,132,549 - 57,140,377 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X64,662,694 - 64,670,530 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FOXO4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X60,893,711 - 60,901,134 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX60,893,526 - 60,902,844 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660652,753,315 - 2,760,992 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Foxo4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249031,391,910 - 1,399,949 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249031,390,899 - 1,399,745 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Foxo4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X59,282,133 - 59,288,854 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Foxo4
5 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:689
Count of miRNA genes:282
Interacting mature miRNAs:369
Transcripts:ENSRNOT00000048521
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX45182909117740458Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X4493088389930883Rat


Genetic Models
This gene Foxo4 is modified in the following models/strains:
SD-Foxo4em1Soar    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 159 91 90 59 92 59 6 356 192 11 138 81 92 31 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000048521   ⟹   ENSRNOP00000042383
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX70,425,563 - 70,432,120 (+)Ensembl
mRatBN7.2 EnsemblX66,385,558 - 66,392,115 (+)Ensembl
Rnor_6.0 EnsemblX71,155,601 - 71,162,158 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076453   ⟹   ENSRNOP00000068509
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX71,155,601 - 71,160,837 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076479   ⟹   ENSRNOP00000068105
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX66,385,851 - 66,392,115 (+)Ensembl
Rnor_6.0 EnsemblX71,155,894 - 71,160,371 (+)Ensembl
RefSeq Acc Id: NM_001106943   ⟹   NP_001100413
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X70,425,563 - 70,432,120 (+)NCBI
mRatBN7.2X66,385,558 - 66,392,115 (+)NCBI
Rnor_6.0X71,155,601 - 71,162,158 (+)NCBI
Rnor_5.0X72,007,762 - 72,014,636 (+)NCBI
RGSC_v3.4X89,332,278 - 89,338,835 (+)RGD
CeleraX66,741,475 - 66,748,019 (+)RGD
Sequence:
RefSeq Acc Id: XM_017601967   ⟹   XP_017457456
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X70,425,218 - 70,432,032 (+)NCBI
mRatBN7.2X66,385,241 - 66,392,027 (+)NCBI
Rnor_6.0X71,155,284 - 71,162,070 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001100413 (Get FASTA)   NCBI Sequence Viewer  
  XP_017457456 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL95908 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000042383
  ENSRNOP00000042383.3
RefSeq Acc Id: NP_001100413   ⟸   NM_001106943
- UniProtKB: D4A433 (UniProtKB/TrEMBL),   A6IQA5 (UniProtKB/TrEMBL),   A0A096MJF0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017457456   ⟸   XM_017601967
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000042383   ⟸   ENSRNOT00000048521
Ensembl Acc Id: ENSRNOP00000068105   ⟸   ENSRNOT00000076479
Ensembl Acc Id: ENSRNOP00000068509   ⟸   ENSRNOT00000076453
Protein Domains
Fork-head

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A433-F1-model_v2 AlphaFold D4A433 1-505 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701871
Promoter ID:EPDNEW_R12395
Type:single initiation site
Name:Foxo4_1
Description:forkhead box O4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X71,155,640 - 71,155,700EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561201 AgrOrtholog
BioCyc Gene G2FUF-2106 BioCyc
Ensembl Genes ENSRNOG00000033316 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000048521 ENTREZGENE
  ENSRNOT00000048521.5 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
InterPro FH_FOXO4 UniProtKB/TrEMBL
  FOXO-TAD UniProtKB/TrEMBL
  TF_fork_head UniProtKB/TrEMBL
  TF_fork_head_CS_2 UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report rno:302415 UniProtKB/TrEMBL
NCBI Gene 302415 ENTREZGENE
PANTHER FORKHEAD BOX PROTEIN O UniProtKB/TrEMBL
  FORKHEAD BOX PROTEIN O4 UniProtKB/TrEMBL
Pfam Fork_head UniProtKB/TrEMBL
  FOXO-TAD UniProtKB/TrEMBL
PhenoGen Foxo4 PhenoGen
PRINTS FORKHEAD UniProtKB/TrEMBL
PROSITE FORK_HEAD_2 UniProtKB/TrEMBL
  FORK_HEAD_3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000033316 RatGTEx
SMART SM00339 UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
UniProt A0A096MJF0 ENTREZGENE
  A6IQA5 ENTREZGENE, UniProtKB/TrEMBL
  D4A433 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-28 Foxo4  forkhead box O4  RGD1561201_predicted  similar to forkhead protein AFXH (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1561201_predicted  similar to forkhead protein AFXH (predicted)  LOC302415  similar to forkhead protein AFXH  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC302415  similar to forkhead protein AFXH      Symbol and Name status set to provisional 70820 PROVISIONAL