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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1561201
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Foxo4
Name: forkhead box O4
Acc ID: CHEBI:52289
Term: wortmannin
Definition: A delta-lactone that has formula C23H24O8.
Chemical ID: MESH:C009687
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Foxo4multiple interactionsISOFOXO4 (Homo sapiens)6480464CTDwortmannin inhibits the reaction [Copper results in increased phosphorylation of FOXO4 protein]; wortmannin inhibits the reaction [Copper Sulfate results in increased phosphorylation of FOXO4 protein]; wortmannin inhibits the reaction [Zinc results in increased phosphorylation of FOXO4 protein]; wortmannin inhibits the reaction [Zinc Sulfate results in increased phosphorylation of FOXO4 protein]PMID:16973122
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