Zfp619 (zinc finger protein 619) - Rat Genome Database

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Gene: Zfp619 (zinc finger protein 619) Rattus norvegicus
Analyze
Symbol: Zfp619
Name: zinc finger protein 619
RGD ID: 7710512
Description: Predicted to enable metal ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine (ortholog); aflatoxin B1 (ortholog); all-trans-retinoic acid (ortholog).
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: LOC102548231; zinc finger protein 709; zinc finger protein 850-like; zinc finger protein 91
RGD Orthologs
Human
Mouse
Bonobo
Dog
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81100,284,802 - 100,304,443 (+)NCBIGRCr8
mRatBN7.2191,148,016 - 91,167,764 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl191,148,121 - 91,166,403 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0194,847,224 - 94,867,345 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0195,947,732 - 95,967,358 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera185,478,342 - 85,497,990 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Zfp619
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81100,284,802 - 100,304,443 (+)NCBIGRCr8
mRatBN7.2191,148,016 - 91,167,764 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl191,148,121 - 91,166,403 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0194,847,224 - 94,867,345 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0195,947,732 - 95,967,358 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera185,478,342 - 85,497,990 (+)NCBICelera
Cytogenetic Map1q21NCBI
ZNF850
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381936,743,480 - 36,772,807 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1936,714,383 - 36,772,825 (-)EnsemblGRCh38hg38GRCh38
GRCh371937,234,382 - 37,263,709 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361941,926,220 - 41,955,556 (-)NCBINCBI36Build 36hg18NCBI36
Celera1934,018,978 - 34,048,283 (-)NCBICelera
Cytogenetic Map19q13.12NCBI
HuRef1933,702,538 - 33,731,814 (-)NCBIHuRef
CHM1_11937,234,817 - 37,264,152 (-)NCBICHM1_1
T2T-CHM13v2.01939,418,764 - 39,448,090 (-)NCBIT2T-CHM13v2.0
Zfp619
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39739,165,143 - 39,189,844 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl739,167,190 - 39,189,844 (+)EnsemblGRCm39 Ensembl
GRCm38739,517,766 - 39,540,415 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl739,517,766 - 39,540,420 (+)EnsemblGRCm38mm10GRCm38
MGSCv37746,773,136 - 46,795,785 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36739,291,970 - 39,314,619 (+)NCBIMGSCv36mm8
Celera734,472,753 - 34,510,037 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map725.48NCBI
ZNF850
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22042,880,024 - 42,915,034 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11944,771,743 - 44,799,298 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01933,704,185 - 33,733,659 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11943,034,645 - 43,063,711 (+)NCBIpanpan1.1PanPan1.1panPan2
LOC102156679
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11115,085,529 - 115,111,448 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1114,489,735 - 114,512,292 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01115,688,520 - 115,711,169 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11115,260,932 - 115,283,498 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01114,867,431 - 114,901,994 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01115,928,786 - 115,954,791 (-)NCBIUU_Cfam_GSD_1.0
ZNF850
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_0236660739,403,829 - 9,439,786 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Zfp619
164 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)17843075491209302Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
4889494Scort2Serum corticosterone level QTL 24.2blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)180592172125592172Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)182174743118944897Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)183547917128547917Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)185424647100358001Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)187580395150700247Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)190532338123479925Rat
1300153Bp171Blood pressure QTL 1713.37arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)190664883143200202Rat


Expression


Sequence


RefSeq Acc Id: ENSRNOT00000094980   ⟹   ENSRNOP00000082543
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl191,148,121 - 91,166,403 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000106390   ⟹   ENSRNOP00000094965
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl191,153,238 - 91,166,403 (+)Ensembl
RefSeq Acc Id: NM_001419774   ⟹   NP_001406703
RefSeq Status: INFERRED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81100,284,810 - 100,304,443 (+)NCBI
mRatBN7.2191,148,128 - 91,167,764 (+)NCBI
RefSeq Acc Id: XM_039100876   ⟹   XP_038956804
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81100,284,802 - 100,304,443 (+)NCBI
mRatBN7.2191,148,016 - 91,167,628 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001406703 (Get FASTA)   NCBI Sequence Viewer  
  XP_038956804 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000082543
  ENSRNOP00000082543.1
  ENSRNOP00000094965.1
RefSeq Acc Id: XP_038956804   ⟸   XM_039100876
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZY46 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000082543   ⟸   ENSRNOT00000094980
RefSeq Acc Id: ENSRNOP00000094965   ⟸   ENSRNOT00000106390
RefSeq Acc Id: NP_001406703   ⟸   NM_001419774
- UniProtKB: A0A8I5ZY46 (UniProtKB/TrEMBL)
Protein Domains
C2H2-type   KRAB

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-59916 BioCyc
Ensembl Genes ENSRNOG00000066986 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000094980 ENTREZGENE
  ENSRNOT00000094980.1 UniProtKB/TrEMBL
  ENSRNOT00000106390.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro KRAB UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene LOC102548231 ENTREZGENE
PANTHER GENE 10130-RELATED UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 619-RELATED UniProtKB/TrEMBL
  ZNF44 PROTEIN UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PhenoGen Zfp619 PhenoGen
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000066986 RatGTEx
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF109640 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A8I5ZY46 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AIR6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-11-29 Zfp619  zinc finger protein 619  LOC102548231  zinc finger protein 850-like  Name and Symbol changed 629549 APPROVED
2013-12-18 LOC102548231  zinc finger protein 850-like      Symbol and Name status set to provisional 70820 PROVISIONAL