Arl6ip1 (ARL6 interacting reticulophagy regulator 1) - Rat Genome Database

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Gene: Arl6ip1 (ARL6 interacting reticulophagy regulator 1) Rattus norvegicus
Analyze
Symbol: Arl6ip1
Name: ARL6 interacting reticulophagy regulator 1 (Ensembl:ADP-ribosylation factor like GTPase 6 interacting protein 1)
RGD ID: 735205
Description: Predicted to enable identical protein binding activity. Predicted to be involved in several processes, including endoplasmic reticulum tubular network organization; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; and positive regulation of L-glutamate import across plasma membrane. Predicted to be located in cytosol and endoplasmic reticulum membrane. Predicted to be part of Sec61 translocon complex. Predicted to be active in endoplasmic reticulum tubular network and membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 61. Orthologous to human ARL6IP1 (ADP ribosylation factor like GTPase 6 interacting protein 1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ADP-ribosylation factor like GTPase 6 interacting protein 1; ADP-ribosylation factor-like 6 interacting protein 1; ADP-ribosylation factor-like protein 6-interacting protein 1; ADP-ribosylation-like factor 6-interacting protein; LOC293551; MGC116042
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81181,864,717 - 181,874,232 (-)NCBIGRCr8
mRatBN7.21172,430,475 - 172,439,990 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1172,430,489 - 172,439,994 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1180,735,631 - 180,745,142 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01187,921,958 - 187,931,469 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01180,651,739 - 180,661,250 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01187,770,160 - 187,779,675 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1187,770,160 - 187,779,675 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01194,724,268 - 194,733,783 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41176,332,729 - 176,342,244 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11176,473,293 - 176,481,481 (-)NCBI
Celera1170,217,077 - 170,226,592 (-)NCBICelera
Cytogenetic Map1q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
aflatoxin B1  (EXP)
amiodarone  (EXP)
amitrole  (EXP)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
buspirone  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
clofibrate  (EXP)
clofibric acid  (EXP)
cobalt dichloride  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
finasteride  (EXP)
folic acid  (ISO)
glafenine  (EXP)
glyphosate  (EXP)
hydroquinone O-beta-D-glucopyranoside  (ISO)
inulin  (ISO)
iron dichloride  (ISO)
L-ethionine  (EXP)
leflunomide  (EXP,ISO)
methapyrilene  (EXP)
methimazole  (EXP)
miconazole  (ISO)
mifepristone  (ISO)
mitomycin C  (ISO)
nefazodone  (EXP)
nickel dichloride  (EXP)
omeprazole  (EXP)
paracetamol  (EXP,ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
senecionine  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sulfadimethoxine  (EXP)
sulindac sulfide  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP,ISO)
tremolite asbestos  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triptonide  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. Characterization, chromosomal localization, and expression during hematopoietic differentiation of the gene encoding Arl6ip, ADP-ribosylation-like factor-6 interacting protein (ARL6). Pettersson M, etal., Genomics 2000 Sep 15;68(3):351-4.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10508919   PMID:12477932   PMID:12754298   PMID:18684713   PMID:19946888   PMID:24262037   PMID:25416956  


Genomics

Comparative Map Data
Arl6ip1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81181,864,717 - 181,874,232 (-)NCBIGRCr8
mRatBN7.21172,430,475 - 172,439,990 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1172,430,489 - 172,439,994 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1180,735,631 - 180,745,142 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01187,921,958 - 187,931,469 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01180,651,739 - 180,661,250 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01187,770,160 - 187,779,675 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1187,770,160 - 187,779,675 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01194,724,268 - 194,733,783 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41176,332,729 - 176,342,244 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11176,473,293 - 176,481,481 (-)NCBI
Celera1170,217,077 - 170,226,592 (-)NCBICelera
Cytogenetic Map1q35NCBI
ARL6IP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381618,791,667 - 18,801,549 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1618,791,609 - 18,801,572 (-)EnsemblGRCh38hg38GRCh38
GRCh371618,802,989 - 18,812,871 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361618,710,492 - 18,720,358 (-)NCBINCBI36Build 36hg18NCBI36
Build 341618,710,491 - 18,720,358NCBI
Celera1617,956,727 - 17,966,592 (-)NCBICelera
Cytogenetic Map16p12.3NCBI
HuRef1617,345,174 - 17,355,038 (-)NCBIHuRef
CHM1_11618,890,472 - 18,900,338 (-)NCBICHM1_1
T2T-CHM13v2.01618,728,102 - 18,737,985 (-)NCBIT2T-CHM13v2.0
Arl6ip1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397117,718,113 - 117,728,848 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7117,718,114 - 117,728,885 (-)EnsemblGRCm39 Ensembl
GRCm387118,118,890 - 118,129,625 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7118,118,891 - 118,129,662 (-)EnsemblGRCm38mm10GRCm38
MGSCv377125,262,404 - 125,273,139 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367117,910,049 - 117,920,712 (-)NCBIMGSCv36mm8
Celera7118,069,686 - 118,079,624 (-)NCBICelera
Cytogenetic Map7F1NCBI
cM Map763.44NCBI
Arl6ip1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554422,540,676 - 2,550,531 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554422,540,676 - 2,550,531 (-)NCBIChiLan1.0ChiLan1.0
ARL6IP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21820,061,411 - 20,071,304 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11624,584,858 - 24,594,743 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01619,478,719 - 19,488,636 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
LOC100856583
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11110,744,146 - 10,744,856 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha11811,764 - 812,478 (+)NCBIDog10K_Boxer_Tasha
Arl6ip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344116,563,497 - 116,572,908 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365014,661,308 - 4,671,306 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365014,648,699 - 4,670,786 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARL6IP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl326,653,979 - 26,770,322 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1326,759,365 - 26,770,325 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ARL6IP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606812,834,783 - 12,845,078 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arl6ip1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247822,240,941 - 2,251,364 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247822,240,940 - 2,251,338 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Arl6ip1
15 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:247
Count of miRNA genes:164
Interacting mature miRNAs:194
Transcripts:ENSRNOT00000024648
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1167909849212909849Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1123350408182418476Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1171629477216629477Rat
2293677Bss41Bone structure and strength QTL 419.380.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1171629477216629477Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1144267353196383668Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
631199Cm23Cardiac mass QTL 234.60.0004heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1115585465172949803Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1151162512201278233Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
2293689Bss47Bone structure and strength QTL 477.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)1171629477216629477Rat
152025235Bw194Body weight QTL 1944.86body mass (VT:0001259)1123556856242907031Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1143506580212458660Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1169537671214537671Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1151162512201278233Rat
4889428Stresp24Stress response QTL 240.05heart pumping trait (VT:2000009)absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)1155866514200866514Rat
152025232Bw192Body weight QTL 1923.93body mass (VT:0001259)1117917486196963478Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
61343Bp28Blood pressure QTL 28arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1151646613196646613Rat
2293693Bss22Bone structure and strength QTL 2233.520.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1171629477216629477Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
2300161Bmd43Bone mineral density QTL 438.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
61347Bp197Blood pressure QTL 1974.2arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1158633083203633083Rat
61348Bp30Blood pressure QTL 302.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1144017057197814409Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1100357752183970443Rat
2303622Vencon6Ventilatory control QTL 60.001respiration trait (VT:0001943)respiration rate (CMO:0000289)1154561505199561505Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1149448574221264292Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118944897199050459Rat
1300158Bp173Blood pressure QTL 1733.48arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1115540693185145286Rat
2300174Bmd42Bone mineral density QTL 428.40.0001lumbar vertebra mineral mass (VT:0010511)bone mineral density (CMO:0001226)1171629477216629477Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1144267353222987745Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1151162766225824951Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
2293654Bss30Bone structure and strength QTL 3032.650.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1171629477216629477Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
2300187Bmd41Bone mineral density QTL 418.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
737974Bp161Blood pressure QTL 1610.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1164747558181133855Rat
1641895Bp298Blood pressure QTL 298arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1123350408182418476Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
634315Niddm45Non-insulin dependent diabetes mellitus QTL 457.16blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1144267916172949660Rat
1358294Bw37Body weight QTL 3750.000011body mass (VT:0001259)body weight (CMO:0000012)1171310381216310381Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
61379Bp44Blood pressure QTL 4419.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1144267916174133260Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1156677124218753816Rat
6893347Bw98Body weight QTL 980.20.53body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1102813953201278233Rat
724550Thym3Thymus enlargement QTL 37.820.001thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1136829932181829932Rat
2312558Glom17Glomerulus QTL 173.90.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1166532971191278129Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
71118Thym1Thymus enlargement QTL 110.170.001thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1136829932181829932Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1164747424209747424Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1136830018181830018Rat
619614Bp78Blood pressure QTL 780.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1169112897197261052Rat
6893361Bw104Body weight QTL 1040.590.27body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1169537671214537671Rat
2292222Bp307Blood pressure QTL 3073.060.0014arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393213533942Rat
738006Anxrr14Anxiety related response QTL 1440.00035locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1130636910175636910Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393243914901Rat
1558645Bw55Body weight QTL 553.20.004body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1102813953201278233Rat
1582204Livw1Liver weight QTL 13.60.0003liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)1155422851172949803Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
738028Anxrr12Anxiety related response QTL 124.90.00001locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1130636910175636910Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512201278233Rat
1354618Kidm15Kidney mass QTL 155kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)1156677124201278233Rat
631544Bp84Blood pressure QTL 845.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350408181759564Rat
152025212Bw190Body weight QTL 1905.7body mass (VT:0001259)1123556856196963478Rat
631549Bp89Blood pressure QTL 895.7arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350581201284552Rat
631548Bp88Blood pressure QTL 8850.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1156677124176484451Rat
1358189Cstrr1Cold stress response QTL 10.0001catecholamine amount (VT:0010543)urine norepinephrine level (CMO:0001629)1123350408182418476Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1151162512201278233Rat

Markers in Region
RH127140  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21172,431,141 - 172,431,350 (+)MAPPERmRatBN7.2
Rnor_6.01187,770,827 - 187,771,035NCBIRnor6.0
Rnor_5.01194,724,935 - 194,725,143UniSTSRnor5.0
RGSC_v3.41176,333,396 - 176,333,604UniSTSRGSC3.4
Celera1170,217,744 - 170,217,952UniSTS
Cytogenetic Map1q35UniSTS
RH128475  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21172,430,649 - 172,430,852 (+)MAPPERmRatBN7.2
Rnor_6.01187,770,335 - 187,770,537NCBIRnor6.0
Rnor_5.01194,724,443 - 194,724,645UniSTSRnor5.0
RGSC_v3.41176,332,904 - 176,333,106UniSTSRGSC3.4
Celera1170,217,252 - 170,217,454UniSTS
Cytogenetic Map1q35UniSTS
D18377  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21172,430,503 - 172,430,702 (+)MAPPERmRatBN7.2
Rnor_6.01187,770,189 - 187,770,387NCBIRnor6.0
Rnor_5.01194,724,297 - 194,724,495UniSTSRnor5.0
RGSC_v3.41176,332,758 - 176,332,956UniSTSRGSC3.4
Celera1170,217,106 - 170,217,304UniSTS
Cytogenetic Map1q35UniSTS
RH129277  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21640,696,990 - 40,697,168 (+)MAPPERmRatBN7.2
mRatBN7.21172,430,592 - 172,430,772 (+)MAPPERmRatBN7.2
Rnor_6.01187,770,278 - 187,770,457NCBIRnor6.0
Rnor_6.01643,481,807 - 43,481,984NCBIRnor6.0
Rnor_5.01643,242,816 - 43,242,993UniSTSRnor5.0
Rnor_5.01194,724,386 - 194,724,565UniSTSRnor5.0
RGSC_v3.41176,332,847 - 176,333,026UniSTSRGSC3.4
RGSC_v3.41643,745,846 - 43,746,023UniSTSRGSC3.4
Celera1638,760,811 - 38,760,988UniSTS
Celera1170,217,195 - 170,217,374UniSTS
Cytogenetic Map1q35UniSTS
AI236718  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21172,434,302 - 172,434,512 (+)MAPPERmRatBN7.2
Rnor_6.01187,773,988 - 187,774,197NCBIRnor6.0
Rnor_5.01194,728,096 - 194,728,305UniSTSRnor5.0
RGSC_v3.41176,336,557 - 176,336,766UniSTSRGSC3.4
Celera1170,220,905 - 170,221,114UniSTS
RH 3.4 Map11562.8UniSTS
Cytogenetic Map1q35UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000024648   ⟹   ENSRNOP00000024648
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1172,430,489 - 172,439,994 (-)Ensembl
Rnor_6.0 Ensembl1187,770,160 - 187,779,675 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000092274
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1187,772,243 - 187,772,767 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000092366
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1187,776,237 - 187,779,674 (-)Ensembl
RefSeq Acc Id: NM_198737   ⟹   NP_942032
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,864,717 - 181,874,232 (-)NCBI
mRatBN7.21172,430,475 - 172,439,990 (-)NCBI
Rnor_6.01187,770,160 - 187,779,675 (-)NCBI
Rnor_5.01194,724,268 - 194,733,783 (-)NCBI
RGSC_v3.41176,332,729 - 176,342,244 (-)RGD
Celera1170,217,077 - 170,226,592 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_942032 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH99071 (Get FASTA)   NCBI Sequence Viewer  
  AAP83442 (Get FASTA)   NCBI Sequence Viewer  
  EDM17717 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000024648.4
RefSeq Acc Id: NP_942032   ⟸   NM_198737
- UniProtKB: Q7TMZ5 (UniProtKB/TrEMBL),   F7EPD6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000024648   ⟸   ENSRNOT00000024648

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TMZ5-F1-model_v2 AlphaFold Q7TMZ5 1-203 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690338
Promoter ID:EPDNEW_R863
Type:single initiation site
Name:Arl6ip1_1
Description:ADP-ribosylation factor like GTPase 6 interacting protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01187,779,690 - 187,779,750EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735205 AgrOrtholog
BioCyc Gene G2FUF-57698 BioCyc
Ensembl Genes ENSRNOG00000017751 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000024648.9 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7381266 IMAGE-MGC_LOAD
InterPro ER_autophagy_membrane_reg UniProtKB/TrEMBL
KEGG Report rno:293551 UniProtKB/TrEMBL
MGC_CLONE MGC:116042 IMAGE-MGC_LOAD
NCBI Gene 293551 ENTREZGENE
PANTHER ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6-INTERACTING PROTEIN 1 UniProtKB/TrEMBL
  ADP-RIBOSYLATION-LIKE FACTOR 6-INTERACTING PROTEIN UniProtKB/TrEMBL
PhenoGen Arl6ip1 PhenoGen
RatGTEx ENSRNOG00000017751 RatGTEx
UniProt F7EPD6 ENTREZGENE, UniProtKB/TrEMBL
  Q7TMZ5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-11-07 Arl6ip1  ARL6 interacting reticulophagy regulator 1  Arl6ip1  ADP-ribosylation factor like GTPase 6 interacting protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-11-19 Arl6ip1  ADP-ribosylation factor like GTPase 6 interacting protein 1  Arl6ip1  ADP-ribosylation factor-like 6 interacting protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-02-25 Arl6ip1  ADP-ribosylation factor-like 6 interacting protein 1  LOC293551  ADP-ribosylation-like factor 6-interacting protein  Symbol and Name updated to reflect Human and Mouse nomenclature 1299863 APPROVED