Vom2r77 (vomeronasal 2 receptor, 77) - Rat Genome Database

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Gene: Vom2r77 (vomeronasal 2 receptor, 77) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Vom2r77
Name: vomeronasal 2 receptor, 77
RGD ID: 1582883
Description: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane; INTERACTS WITH cadmium dichloride; valproic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC690227; similar to vomeronasal 2, receptor, 1; vomeronasal 2 receptor 77
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr899,900,049 - 9,966,052 (-)NCBIGRCr8
mRatBN7.299,572,874 - 9,638,896 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl99,572,073 - 9,639,044 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx912,602,845 - 12,668,854 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0916,841,351 - 16,907,362 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0915,603,324 - 15,669,329 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.097,749,090 - 7,815,144 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl97,749,090 - 7,815,144 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.096,788,535 - 6,854,589 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera95,348,088 - 5,414,088 (-)NCBICelera
Cytogenetic Map9q11-q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17382427  


Genomics

Variants

.
Variants in Vom2r77
538 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:106
Count of miRNA genes:83
Interacting mature miRNAs:84
Transcripts:ENSRNOT00000072966
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
10054141Gmadr4Adrenal mass QTL 42.450.0074adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)9114209783Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)9795472022071169Rat
1578675Bss17Bone structure and strength QTL 173.8femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)9336865213533896Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat


Expression

RNA-SEQ Expression

ectoderm
endocrine system
endoderm
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
18 2 2 2 3 1 15 2 14 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001099519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000072966   ⟹   ENSRNOP00000066193
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl99,572,073 - 9,639,044 (-)Ensembl
Rnor_6.0 Ensembl97,749,090 - 7,815,144 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095714   ⟹   ENSRNOP00000090732
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl99,572,073 - 9,577,191 (-)Ensembl
RefSeq Acc Id: NM_001099519   ⟹   NP_001092989
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr899,900,049 - 9,966,052 (-)NCBI
mRatBN7.299,572,874 - 9,638,896 (-)NCBI
Rnor_6.097,749,090 - 7,815,144 (-)NCBI
Rnor_5.096,788,535 - 6,854,589 (-)NCBI
Celera95,348,088 - 5,414,088 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001092989 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000066193.1
  ENSRNOP00000090732.1
RefSeq Acc Id: NP_001092989   ⟸   NM_001099519
- Peptide Label: precursor
- UniProtKB: M0R9L8 (UniProtKB/TrEMBL),   A6KQA7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000066193   ⟸   ENSRNOT00000072966
Ensembl Acc Id: ENSRNOP00000090732   ⟸   ENSRNOT00000095714
Protein Domains
G-protein coupled receptors family 3 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R9L8-F1-model_v2 AlphaFold M0R9L8 1-849 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1582883 AgrOrtholog
BioCyc Gene G2FUF-28370 BioCyc
Ensembl Genes ENSRNOG00000049443 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000072966.2 UniProtKB/TrEMBL
  ENSRNOT00000095714.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.50.30 UniProtKB/TrEMBL
  3.40.50.2300 UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/TrEMBL
  GPCR_3 UniProtKB/TrEMBL
  GPCR_3_9-Cys_dom UniProtKB/TrEMBL
  GPCR_3_9-Cys_sf UniProtKB/TrEMBL
  GPCR_3_C UniProtKB/TrEMBL
  GPCR_3_Ca_sens_rcpt-rel UniProtKB/TrEMBL
  GPCR_3_vmron_rcpt_2 UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/TrEMBL
KEGG Report rno:690227 UniProtKB/TrEMBL
NCBI Gene 690227 ENTREZGENE
PANTHER PTHR24061 UniProtKB/TrEMBL
  VOMERONASAL 2, RECEPTOR 118-RELATED UniProtKB/TrEMBL
Pfam 7tm_3 UniProtKB/TrEMBL
  ANF_receptor UniProtKB/TrEMBL
  NCD3G UniProtKB/TrEMBL
PhenoGen Vom2r77 PhenoGen
PRINTS GPCRMGR UniProtKB/TrEMBL
  VOMERONASL2R UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F3_4 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000049443 RatGTEx
Superfamily-SCOP SSF53822 UniProtKB/TrEMBL
UniProt A0A8I6AP23_RAT UniProtKB/TrEMBL
  A6KQA7 ENTREZGENE, UniProtKB/TrEMBL
  M0R9L8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Vom2r77  vomeronasal 2 receptor, 77  LOC681780  similar to vomeronasal 2, receptor, 1  Data merged from RGD:1591625 1643240 APPROVED
2008-07-23 Vom2r77  vomeronasal 2 receptor, 77  LOC690227  similar to vomeronasal 2, receptor, 1  Symbol and Name updated 1299863 APPROVED
2006-11-20 LOC681780  similar to vomeronasal 2, receptor, 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC690227  similar to vomeronasal 2, receptor, 1      Symbol and Name status set to provisional 70820 PROVISIONAL